DASMIweb: online integration, analysis and assessment of distributed protein interaction data
Identifieur interne : 000C16 ( Main/Merge ); précédent : 000C15; suivant : 000C17DASMIweb: online integration, analysis and assessment of distributed protein interaction data
Auteurs : Hagen Blankenburg ; Fidel Ramírez ; Joachim Büch ; Mario AlbrechtSource :
- Nucleic Acids Research [ 0305-1048 ] ; 2009.
Abstract
In recent years, we have witnessed a substantial increase of the amount of available protein interaction data. However, most data are currently not readily accessible to the biologist at a single site, but scattered over multiple online repositories. Therefore, we have developed the DASMIweb server that affords the integration, analysis and qualitative assessment of distributed sources of interaction data in a dynamic fashion. Since DASMIweb allows for querying many different resources of protein and domain interactions simultaneously, it serves as an important starting point for interactome studies and assists the user in finding publicly accessible interaction data with minimal effort. The pool of queried resources is fully configurable and supports the inclusion of own interaction data or confidence scores. In particular, DASMIweb integrates confidence measures like functional similarity scores to assess individual interactions. The retrieved results can be exported in different file formats like MITAB or SIF. DASMIweb is freely available at
Url:
DOI: 10.1093/nar/gkp438
PubMed: 19502495
PubMed Central: 2703953
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 000575
- to stream Pmc, to step Curation: 000575
- to stream Pmc, to step Checkpoint: 000644
- to stream Ncbi, to step Merge: 000087
- to stream Ncbi, to step Curation: 000087
- to stream Ncbi, to step Checkpoint: 000087
Links to Exploration step
PMC:2703953Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">DASMIweb: online integration, analysis and assessment of distributed protein interaction data</title><author><name sortKey="Blankenburg, Hagen" sort="Blankenburg, Hagen" uniqKey="Blankenburg H" first="Hagen" last="Blankenburg">Hagen Blankenburg</name></author><author><name sortKey="Ramirez, Fidel" sort="Ramirez, Fidel" uniqKey="Ramirez F" first="Fidel" last="Ramírez">Fidel Ramírez</name></author><author><name sortKey="Buch, Joachim" sort="Buch, Joachim" uniqKey="Buch J" first="Joachim" last="Büch">Joachim Büch</name></author><author><name sortKey="Albrecht, Mario" sort="Albrecht, Mario" uniqKey="Albrecht M" first="Mario" last="Albrecht">Mario Albrecht</name></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">19502495</idno><idno type="pmc">2703953</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2703953</idno><idno type="RBID">PMC:2703953</idno><idno type="doi">10.1093/nar/gkp438</idno><date when="2009">2009</date><idno type="wicri:Area/Pmc/Corpus">000575</idno><idno type="wicri:Area/Pmc/Curation">000575</idno><idno type="wicri:Area/Pmc/Checkpoint">000644</idno><idno type="wicri:Area/Ncbi/Merge">000087</idno><idno type="wicri:Area/Ncbi/Curation">000087</idno><idno type="wicri:Area/Ncbi/Checkpoint">000087</idno><idno type="wicri:doubleKey">0305-1048:2009:Blankenburg H:dasmiweb:online:integration</idno><idno type="wicri:Area/Main/Merge">000C16</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">DASMIweb: online integration, analysis and assessment of distributed protein interaction data</title><author><name sortKey="Blankenburg, Hagen" sort="Blankenburg, Hagen" uniqKey="Blankenburg H" first="Hagen" last="Blankenburg">Hagen Blankenburg</name></author><author><name sortKey="Ramirez, Fidel" sort="Ramirez, Fidel" uniqKey="Ramirez F" first="Fidel" last="Ramírez">Fidel Ramírez</name></author><author><name sortKey="Buch, Joachim" sort="Buch, Joachim" uniqKey="Buch J" first="Joachim" last="Büch">Joachim Büch</name></author><author><name sortKey="Albrecht, Mario" sort="Albrecht, Mario" uniqKey="Albrecht M" first="Mario" last="Albrecht">Mario Albrecht</name></author></analytic><series><title level="j">Nucleic Acids Research</title><idno type="ISSN">0305-1048</idno><idno type="eISSN">1362-4962</idno><imprint><date when="2009">2009</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>In recent years, we have witnessed a substantial increase of the amount of available protein interaction data. However, most data are currently not readily accessible to the biologist at a single site, but scattered over multiple online repositories. Therefore, we have developed the DASMIweb server that affords the integration, analysis and qualitative assessment of distributed sources of interaction data in a dynamic fashion. Since DASMIweb allows for querying many different resources of protein and domain interactions simultaneously, it serves as an important starting point for interactome studies and assists the user in finding publicly accessible interaction data with minimal effort. The pool of queried resources is fully configurable and supports the inclusion of own interaction data or confidence scores. In particular, DASMIweb integrates confidence measures like functional similarity scores to assess individual interactions. The retrieved results can be exported in different file formats like MITAB or SIF. DASMIweb is freely available at <ext-link ext-link-type="uri" xlink:href="http://www.dasmiweb.de">http://www.dasmiweb.de</ext-link>.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Frishman, D" uniqKey="Frishman D">D Frishman</name></author><author><name sortKey="Albrecht, M" uniqKey="Albrecht M">M Albrecht</name></author><author><name sortKey="Blankenburg, H" uniqKey="Blankenburg H">H Blankenburg</name></author><author><name sortKey="Bork, P" uniqKey="Bork P">P Bork</name></author><author><name sortKey="Harrington, Ed" uniqKey="Harrington E">ED Harrington</name></author><author><name sortKey="Hermjakob, H" uniqKey="Hermjakob H">H Hermjakob</name></author><author><name sortKey="Jensen, Lj" uniqKey="Jensen L">LJ Jensen</name></author><author><name sortKey="Juan, Da" uniqKey="Juan D">DA Juan</name></author><author><name sortKey="Lengauer, T" uniqKey="Lengauer T">T Lengauer</name></author><author><name sortKey="Pagel, P" 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