Metagenomic analysis: the challenge of the data bonanza
Identifieur interne : 000484 ( Main/Merge ); précédent : 000483; suivant : 000485Metagenomic analysis: the challenge of the data bonanza
Auteurs : Chris I. Hunter ; Alex Mitchell ; Philip Jones ; Craig Mcanulla ; Sebastien Pesseat ; Maxim Scheremetjew ; Sarah HunterSource :
- Briefings in Bioinformatics [ 1467-5463 ] ; 2012.
Abstract
Several thousand metagenomes have already been sequenced, and this number is set to grow rapidly in the forthcoming years as the uptake of high-throughput sequencing technologies continues. Hand-in-hand with this data bonanza comes the computationally overwhelming task of analysis. Herein, we describe some of the bioinformatic approaches currently used by metagenomics researchers to analyze their data, the issues they face and the steps that could be taken to help overcome these challenges.
Url:
DOI: 10.1093/bib/bbs020
PubMed: 22962339
PubMed Central: 3504930
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Hunter</name></author><author><name sortKey="Mitchell, Alex" sort="Mitchell, Alex" uniqKey="Mitchell A" first="Alex" last="Mitchell">Alex Mitchell</name></author><author><name sortKey="Jones, Philip" sort="Jones, Philip" uniqKey="Jones P" first="Philip" last="Jones">Philip Jones</name></author><author><name sortKey="Mcanulla, Craig" sort="Mcanulla, Craig" uniqKey="Mcanulla C" first="Craig" last="Mcanulla">Craig Mcanulla</name></author><author><name sortKey="Pesseat, Sebastien" sort="Pesseat, Sebastien" uniqKey="Pesseat S" first="Sebastien" last="Pesseat">Sebastien Pesseat</name></author><author><name sortKey="Scheremetjew, Maxim" sort="Scheremetjew, Maxim" uniqKey="Scheremetjew M" first="Maxim" last="Scheremetjew">Maxim Scheremetjew</name></author><author><name sortKey="Hunter, Sarah" sort="Hunter, Sarah" uniqKey="Hunter S" first="Sarah" last="Hunter">Sarah Hunter</name></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">22962339</idno><idno type="pmc">3504930</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3504930</idno><idno type="RBID">PMC:3504930</idno><idno type="doi">10.1093/bib/bbs020</idno><date when="2012">2012</date><idno type="wicri:Area/Pmc/Corpus">000508</idno><idno type="wicri:Area/Pmc/Curation">000508</idno><idno type="wicri:Area/Pmc/Checkpoint">000394</idno><idno type="wicri:Area/Ncbi/Merge">000350</idno><idno type="wicri:Area/Ncbi/Curation">000350</idno><idno type="wicri:Area/Ncbi/Checkpoint">000350</idno><idno type="wicri:doubleKey">1467-5463:2012:Hunter C:metagenomic:analysis:the</idno><idno type="wicri:Area/Main/Merge">000484</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Metagenomic analysis: the challenge of the data bonanza</title><author><name sortKey="Hunter, Chris I" sort="Hunter, Chris I" uniqKey="Hunter C" first="Chris I." last="Hunter">Chris I. 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