Data publication with the structural biology data grid supports live analysis
Identifieur interne : 000040 ( Main/Merge ); précédent : 000039; suivant : 000041Data publication with the structural biology data grid supports live analysis
Auteurs : Peter A. Meyer [États-Unis] ; Stephanie Socias [États-Unis] ; Jason Key [États-Unis] ; Elizabeth Ransey [États-Unis] ; Emily C. Tjon [États-Unis] ; Alejandro Buschiazzo [Uruguay, France] ; Ming Lei [République populaire de Chine] ; Chris Botka [États-Unis] ; James Withrow [États-Unis] ; David Neau [États-Unis] ; Kanagalaghatta Rajashankar [États-Unis] ; Karen S. Anderson [États-Unis] ; Richard H. Baxter [États-Unis] ; Stephen C. Blacklow [États-Unis] ; Titus J. Boggon [États-Unis] ; Alexandre M. J. J. Bonvin [Pays-Bas] ; Dominika Borek [États-Unis] ; Tom J. Brett [États-Unis] ; Amedeo Caflisch [Suisse] ; Chung-I Chang [Taïwan] ; Walter J. Chazin [États-Unis] ; Kevin D. Corbett [États-Unis] ; Michael S. Cosgrove [États-Unis] ; Sean Crosson [États-Unis] ; Sirano Dhe-Paganon [États-Unis] ; Enrico Di Cera [États-Unis] ; Catherine L. Drennan [États-Unis] ; Michael J. Eck [États-Unis] ; Brandt F. Eichman [États-Unis] ; Qing R. Fan [États-Unis] ; Adrian R. Ferré-D'Amaré [États-Unis] ; J. Christopher Fromme [États-Unis] ; K. Christopher Garcia [États-Unis] ; Rachelle Gaudet [États-Unis] ; Peng Gong [République populaire de Chine] ; Stephen C. Harrison [États-Unis] ; Ekaterina E. Heldwein [États-Unis] ; Zongchao Jia [Canada] ; Robert J. Keenan [États-Unis] ; Andrew C. Kruse [États-Unis] ; Marc Kvansakul [Australie] ; Jason S. Mclellan [États-Unis] ; Yorgo Modis [Royaume-Uni] ; Yunsun Nam [États-Unis] ; Zbyszek Otwinowski [États-Unis] ; Emil F. Pai [Canada] ; Pedro José Barbosa Pereira [Portugal] ; Carlo Petosa [France] ; C. S. Raman [États-Unis] ; Tom A. Rapoport [États-Unis] ; Antonina Roll-Mecak [États-Unis] ; Michael K. Rosen [États-Unis] ; Gabby Rudenko [États-Unis] ; Joseph Schlessinger [États-Unis] ; Thomas U. Schwartz [États-Unis] ; Yousif Shamoo [États-Unis] ; Holger Sondermann [États-Unis] ; Yizhi J. Tao [États-Unis] ; Niraj H. Tolia [États-Unis] ; Oleg V. Tsodikov [États-Unis] ; Kenneth D. Westover [États-Unis] ; Hao Wu [États-Unis] ; Ian Foster [États-Unis] ; James S. Fraser [États-Unis] ; Filipe R. N C. Maia [Suède, États-Unis] ; Tamir Gonen [États-Unis] ; Tom Kirchhausen [États-Unis] ; Kay Diederichs [Allemagne] ; Mercè Crosas [États-Unis] ; Piotr Sliz [États-Unis]Source :
- Nature Communications [ 2041-1723 ] ; 2016.
Abstract
Access to experimental X-ray diffraction image data is fundamental for validation and reproduction of macromolecular models and indispensable for development of structural biology processing methods. Here, we established a diffraction data publication and dissemination system, Structural Biology Data Grid (SBDG; data.sbgrid.org), to preserve primary experimental data sets that support scientific publications. Data sets are accessible to researchers through a community driven data grid, which facilitates global data access. Our analysis of a pilot collection of crystallographic data sets demonstrates that the information archived by SBDG is sufficient to reprocess data to statistics that meet or exceed the quality of the original published structures. SBDG has extended its services to the entire community and is used to develop support for other types of biomedical data sets. It is anticipated that access to the experimental data sets will enhance the paradigm shift in the community towards a much more dynamic body of continuously improving data analysis.
Url:
DOI: 10.1038/ncomms10882
PubMed: 26947396
PubMed Central: 4786681
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PMC:4786681Le document en format XML
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<author><name sortKey="Anderson, Karen S" sort="Anderson, Karen S" uniqKey="Anderson K" first="Karen S." last="Anderson">Karen S. Anderson</name>
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<author><name sortKey="Bonvin, Alexandre M J J" sort="Bonvin, Alexandre M J J" uniqKey="Bonvin A" first="Alexandre M. J. J." last="Bonvin">Alexandre M. J. J. Bonvin</name>
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<author><name sortKey="Chang, Chung I" sort="Chang, Chung I" uniqKey="Chang C" first="Chung-I" last="Chang">Chung-I Chang</name>
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, Nashville, Tennessee 37232,<country>USA</country>
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<country xml:lang="fr">États-Unis</country>
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<author><name sortKey="Corbett, Kevin D" sort="Corbett, Kevin D" uniqKey="Corbett K" first="Kevin D." last="Corbett">Kevin D. Corbett</name>
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</nlm:aff>
<country xml:lang="fr">États-Unis</country>
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<affiliation wicri:level="1"><nlm:aff id="a16"><institution>Department of Cellular and Molecular Medicine, University of California, San Diego</institution>
, La Jolla, California 92093,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
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<author><name sortKey="Cosgrove, Michael S" sort="Cosgrove, Michael S" uniqKey="Cosgrove M" first="Michael S." last="Cosgrove">Michael S. Cosgrove</name>
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, Syracuse, New York 13210,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
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<author><name sortKey="Crosson, Sean" sort="Crosson, Sean" uniqKey="Crosson S" first="Sean" last="Crosson">Sean Crosson</name>
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, Chicago, Illinois 60637,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
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<author><name sortKey="Dhe Paganon, Sirano" sort="Dhe Paganon, Sirano" uniqKey="Dhe Paganon S" first="Sirano" last="Dhe-Paganon">Sirano Dhe-Paganon</name>
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, Boston, Massachusetts 02115,<country>USA</country>
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<country xml:lang="fr">États-Unis</country>
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<author><name sortKey="Di Cera, Enrico" sort="Di Cera, Enrico" uniqKey="Di Cera E" first="Enrico" last="Di Cera">Enrico Di Cera</name>
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, St Louis, Missouri 63104,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
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<author><name sortKey="Drennan, Catherine L" sort="Drennan, Catherine L" uniqKey="Drennan C" first="Catherine L." last="Drennan">Catherine L. Drennan</name>
<affiliation wicri:level="1"><nlm:aff id="a21"><institution>Departments of Chemistry and Biology and the Howard Hughes Medical Institute, Massachusetts Institute of Technology</institution>
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</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
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<author><name sortKey="Eck, Michael J" sort="Eck, Michael J" uniqKey="Eck M" first="Michael J." last="Eck">Michael J. Eck</name>
<affiliation wicri:level="1"><nlm:aff id="a1"><institution>Department of Biological Chemistry and Molecular Pharmacology</institution>
, Boston, Massachusetts 02115,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="a19"><institution>Department of Cancer Biology, Dana-Farber Cancer Institute</institution>
, Boston, Massachusetts 02115,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
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<author><name sortKey="Eichman, Brandt F" sort="Eichman, Brandt F" uniqKey="Eichman B" first="Brandt F." last="Eichman">Brandt F. Eichman</name>
<affiliation wicri:level="1"><nlm:aff id="a22"><institution>Department of Biological Sciences and Center for Structural Biology, Vanderbilt University</institution>
, Nashville, Tennessee 37235,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
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<author><name sortKey="Fan, Qing R" sort="Fan, Qing R" uniqKey="Fan Q" first="Qing R." last="Fan">Qing R. Fan</name>
<affiliation wicri:level="1"><nlm:aff id="a23"><institution>Departments of Pharmacology and Pathology and Cell Biology, Columbia University</institution>
, New York, New York 10032,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
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<author><name sortKey="Ferre D Amare, Adrian R" sort="Ferre D Amare, Adrian R" uniqKey="Ferre D Amare A" first="Adrian R." last="Ferré-D'Amaré">Adrian R. Ferré-D'Amaré</name>
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<author><name sortKey="Christopher Fromme, J" sort="Christopher Fromme, J" uniqKey="Christopher Fromme J" first="J." last="Christopher Fromme">J. Christopher Fromme</name>
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, Ithaca, New York 14853,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
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<author><name sortKey="Garcia, K Christopher" sort="Garcia, K Christopher" uniqKey="Garcia K" first="K. Christopher" last="Garcia">K. Christopher Garcia</name>
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</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="a27"><institution>Department of Molecular and Cellular Physiology, Stanford University School of Medicine</institution>
, Stanford, California 94305,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="a28"><institution>Department of Structural Biology, Stanford University School of Medicine</institution>
, Stanford, California 94305,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
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<author><name sortKey="Gaudet, Rachelle" sort="Gaudet, Rachelle" uniqKey="Gaudet R" first="Rachelle" last="Gaudet">Rachelle Gaudet</name>
<affiliation wicri:level="1"><nlm:aff id="a29"><institution>Department of Molecular and Cellular Biology, Harvard University</institution>
, Cambridge, Massachusetts 02138,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
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<author><name sortKey="Gong, Peng" sort="Gong, Peng" uniqKey="Gong P" first="Peng" last="Gong">Peng Gong</name>
<affiliation wicri:level="1"><nlm:aff id="a30"><institution>Key Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virology, Chinese Academy of Sciences</institution>
, Wuhan 430071,<country>China</country>
</nlm:aff>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
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<author><name sortKey="Harrison, Stephen C" sort="Harrison, Stephen C" uniqKey="Harrison S" first="Stephen C." last="Harrison">Stephen C. Harrison</name>
<affiliation wicri:level="1"><nlm:aff id="a1"><institution>Department of Biological Chemistry and Molecular Pharmacology</institution>
, Boston, Massachusetts 02115,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="a31"><institution>Howard Hughes Medical Institute, Harvard Medical School</institution>
, Boston, Massachusetts 02115,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="a32"><institution>Laboratory of Molecular Medicine, Boston Children's Hospital, Harvard Medical School</institution>
, Boston, Massachusetts 02115,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Heldwein, Ekaterina E" sort="Heldwein, Ekaterina E" uniqKey="Heldwein E" first="Ekaterina E." last="Heldwein">Ekaterina E. Heldwein</name>
<affiliation wicri:level="1"><nlm:aff id="a33"><institution>Department of Molecular Biology and Microbiology, Tufts University School of Medicine</institution>
, Boston, Massachusetts 02111,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Jia, Zongchao" sort="Jia, Zongchao" uniqKey="Jia Z" first="Zongchao" last="Jia">Zongchao Jia</name>
<affiliation wicri:level="1"><nlm:aff id="a34"><institution>Department of Biomedical and Molecular Sciences, Queen's University</institution>
, Kingston, Ontario,<country>Canada</country>
K7M 3G5</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Keenan, Robert J" sort="Keenan, Robert J" uniqKey="Keenan R" first="Robert J." last="Keenan">Robert J. Keenan</name>
<affiliation wicri:level="1"><nlm:aff id="a18"><institution>Department of Biochemistry and Molecular Biology, University of Chicago</institution>
, Chicago, Illinois 60637,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Kruse, Andrew C" sort="Kruse, Andrew C" uniqKey="Kruse A" first="Andrew C." last="Kruse">Andrew C. Kruse</name>
<affiliation wicri:level="1"><nlm:aff id="a1"><institution>Department of Biological Chemistry and Molecular Pharmacology</institution>
, Boston, Massachusetts 02115,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Kvansakul, Marc" sort="Kvansakul, Marc" uniqKey="Kvansakul M" first="Marc" last="Kvansakul">Marc Kvansakul</name>
<affiliation wicri:level="1"><nlm:aff id="a35"><institution>Department of Biochemistry and Genetics, La Trobe University</institution>
, Melbourne, Victoria 3086,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Mclellan, Jason S" sort="Mclellan, Jason S" uniqKey="Mclellan J" first="Jason S." last="Mclellan">Jason S. Mclellan</name>
<affiliation wicri:level="1"><nlm:aff id="a36"><institution>Department of Biochemistry, Geisel School of Medicine at Dartmouth</institution>
, Hanover, New Hampshire 03755,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Modis, Yorgo" sort="Modis, Yorgo" uniqKey="Modis Y" first="Yorgo" last="Modis">Yorgo Modis</name>
<affiliation wicri:level="1"><nlm:aff id="a37"><institution>Department of Medicine, University of Cambridge, MRC Laboratory of Molecular Biology</institution>
, Francis Crick Avenue, Cambridge CB2 0QH,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Nam, Yunsun" sort="Nam, Yunsun" uniqKey="Nam Y" first="Yunsun" last="Nam">Yunsun Nam</name>
<affiliation wicri:level="1"><nlm:aff id="a38"><institution>University of Texas, Southwestern Medical Center</institution>
, Dallas, Texas 75390,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Otwinowski, Zbyszek" sort="Otwinowski, Zbyszek" uniqKey="Otwinowski Z" first="Zbyszek" last="Otwinowski">Zbyszek Otwinowski</name>
<affiliation wicri:level="1"><nlm:aff id="a10"><institution>Departments of Biophysics and Biochemistry, University of Texas Southwestern Medical Center</institution>
, Dallas, Texas 75390,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Pai, Emil F" sort="Pai, Emil F" uniqKey="Pai E" first="Emil F." last="Pai">Emil F. Pai</name>
<affiliation wicri:level="1"><nlm:aff id="a39"><institution>Departments of Biochemistry, Medical Biophysics and Molecular Genetics, University of Toronto</institution>
, Toronto, Ontario,<country>Canada</country>
M5S 1A8</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="a40"><institution>Campbell Family Institute for Cancer Research, Ontario Cancer Institute/University Health Network</institution>
, Toronto, Ontario,<country>Canada</country>
M5G 2M9</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Pereira, Pedro Jose Barbosa" sort="Pereira, Pedro Jose Barbosa" uniqKey="Pereira P" first="Pedro José Barbosa" last="Pereira">Pedro José Barbosa Pereira</name>
<affiliation wicri:level="1"><nlm:aff id="a41"><institution>IBMC—Instituto de Biologia Molecular e Celular and Instituto de Investigação e Inovação em Saúde, Universidade do Porto</institution>
, 4150 Porto,<country>Portugal</country>
</nlm:aff>
<country xml:lang="fr">Portugal</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Petosa, Carlo" sort="Petosa, Carlo" uniqKey="Petosa C" first="Carlo" last="Petosa">Carlo Petosa</name>
<affiliation wicri:level="1"><nlm:aff id="a42"><institution>Université Grenoble Alpes/CNRS/CEA, Institut de Biologie Structurale</institution>
, 38027 Grenoble,<country>France</country>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Raman, C S" sort="Raman, C S" uniqKey="Raman C" first="C. S." last="Raman">C. S. Raman</name>
<affiliation wicri:level="1"><nlm:aff id="a43"><institution>Department of Pharmaceutical Sciences, University of Maryland</institution>
, Baltimore, Maryland 21201,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Rapoport, Tom A" sort="Rapoport, Tom A" uniqKey="Rapoport T" first="Tom A." last="Rapoport">Tom A. Rapoport</name>
<affiliation wicri:level="1"><nlm:aff id="a44"><institution>Howard Hughes Medical Institute and Harvard Medical School, Department of Cell Biology</institution>
, Boston, Massachusetts 02115,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Roll Mecak, Antonina" sort="Roll Mecak, Antonina" uniqKey="Roll Mecak A" first="Antonina" last="Roll-Mecak">Antonina Roll-Mecak</name>
<affiliation wicri:level="1"><nlm:aff id="a45"><institution>Cell Biology and Biophysics Unit, Porter Neuroscience Research Center, National Institute of Neurological Disorders and Stroke</institution>
, Bethesda, Maryland 20892,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="a46"><institution>National Heart, Lung and Blood Institute</institution>
, Bethesda, Maryland 20892,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Rosen, Michael K" sort="Rosen, Michael K" uniqKey="Rosen M" first="Michael K." last="Rosen">Michael K. Rosen</name>
<affiliation wicri:level="1"><nlm:aff id="a47"><institution>Department of Biophysics and Howard Hughes Medical Institute, University of Texas Southwestern Medical Center</institution>
, Dallas, Texas 75390,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Rudenko, Gabby" sort="Rudenko, Gabby" uniqKey="Rudenko G" first="Gabby" last="Rudenko">Gabby Rudenko</name>
<affiliation wicri:level="1"><nlm:aff id="a48"><institution>Department of Pharmacology and Toxicology, Sealy Center for Structural Biology and Molecular Biophysics, University of Texas Medical Branch</institution>
, Galveston, Texas 77555,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Schlessinger, Joseph" sort="Schlessinger, Joseph" uniqKey="Schlessinger J" first="Joseph" last="Schlessinger">Joseph Schlessinger</name>
<affiliation wicri:level="1"><nlm:aff id="a49"><institution>Department of Pharmacology, Yale University School of Medicine</institution>
, New Haven, Connecticut 06520,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Schwartz, Thomas U" sort="Schwartz, Thomas U" uniqKey="Schwartz T" first="Thomas U." last="Schwartz">Thomas U. Schwartz</name>
<affiliation wicri:level="1"><nlm:aff id="a50"><institution>Department of Biology, Massachusetts Institute of Technology</institution>
, Cambridge, Massachusetts 02139,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Shamoo, Yousif" sort="Shamoo, Yousif" uniqKey="Shamoo Y" first="Yousif" last="Shamoo">Yousif Shamoo</name>
<affiliation wicri:level="1"><nlm:aff id="a51"><institution>Department of BioSciences, Rice University</institution>
, Houston, Texas 77005,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Sondermann, Holger" sort="Sondermann, Holger" uniqKey="Sondermann H" first="Holger" last="Sondermann">Holger Sondermann</name>
<affiliation wicri:level="1"><nlm:aff id="a52"><institution>Department of Molecular Medicine, College of Veterinary Medicine, Cornell University</institution>
, Ithaca, New York 14853,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Tao, Yizhi J" sort="Tao, Yizhi J" uniqKey="Tao Y" first="Yizhi J." last="Tao">Yizhi J. Tao</name>
<affiliation wicri:level="1"><nlm:aff id="a51"><institution>Department of BioSciences, Rice University</institution>
, Houston, Texas 77005,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Tolia, Niraj H" sort="Tolia, Niraj H" uniqKey="Tolia N" first="Niraj H." last="Tolia">Niraj H. Tolia</name>
<affiliation wicri:level="1"><nlm:aff id="a53"><institution>Department of Molecular Microbiology, Washington University School of Medicine</institution>
, St Louis, Missouri 63110,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Tsodikov, Oleg V" sort="Tsodikov, Oleg V" uniqKey="Tsodikov O" first="Oleg V." last="Tsodikov">Oleg V. Tsodikov</name>
<affiliation wicri:level="1"><nlm:aff id="a54"><institution>Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky</institution>
, Lexington, Kentucky 40536,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Westover, Kenneth D" sort="Westover, Kenneth D" uniqKey="Westover K" first="Kenneth D." last="Westover">Kenneth D. Westover</name>
<affiliation wicri:level="1"><nlm:aff id="a55"><institution>Departments of Biochemistry and Radiation Oncology, University of Texas, Southwestern Medical Center</institution>
, Dallas, Texas 75390,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Wu, Hao" sort="Wu, Hao" uniqKey="Wu H" first="Hao" last="Wu">Hao Wu</name>
<affiliation wicri:level="1"><nlm:aff id="a1"><institution>Department of Biological Chemistry and Molecular Pharmacology</institution>
, Boston, Massachusetts 02115,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="a56"><institution>Program in Cellular and Molecular Medicine, Boston Children's Hospital</institution>
, Boston, Massachusetts 02115,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Foster, Ian" sort="Foster, Ian" uniqKey="Foster I" first="Ian" last="Foster">Ian Foster</name>
<affiliation wicri:level="1"><nlm:aff id="a57"><institution>Mathematics and Computer Science Division, Argonne National Laboratory, Argonne, Illinois, and Department of Computer Science, University of Chicago</institution>
, Chicago, Illinois 60637,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Fraser, James S" sort="Fraser, James S" uniqKey="Fraser J" first="James S." last="Fraser">James S. Fraser</name>
<affiliation wicri:level="1"><nlm:aff id="a58"><institution>Department of Bioengineering and Therapeutic Sciences, University of California San Francisco</institution>
, San Francisco, California 94158,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Maia, Filipe R N C" sort="Maia, Filipe R N C" uniqKey="Maia F" first="Filipe R. N C." last="Maia">Filipe R. N C. Maia</name>
<affiliation wicri:level="1"><nlm:aff id="a59"><institution>Laboratory of Molecular Biophysics, Department of Cell and Molecular Biology, Uppsala University</institution>
, Husargatan 3 (Box 596), SE-751 24 Uppsala,<country>Sweden</country>
</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="a60"><institution>NERSC, Lawrence Berkeley National Laboratory</institution>
, Berkeley, California 94720,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Gonen, Tamir" sort="Gonen, Tamir" uniqKey="Gonen T" first="Tamir" last="Gonen">Tamir Gonen</name>
<affiliation wicri:level="1"><nlm:aff id="a61"><institution>Janelia Research Campus, Howard Hughes Medical Institute</institution>
, Ashburn, Virginia 20147<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Kirchhausen, Tom" sort="Kirchhausen, Tom" uniqKey="Kirchhausen T" first="Tom" last="Kirchhausen">Tom Kirchhausen</name>
<affiliation wicri:level="1"><nlm:aff id="a62"><institution>Program in Cellular and Molecular Medicine and Department of Pediatrics, Boston Children's Hospital</institution>
, Boston, Massachusetts 02115,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="a63"><institution>Departments of Cell Biology, Harvard Medical School</institution>
, Boston, Massachusetts 02115,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Diederichs, Kay" sort="Diederichs, Kay" uniqKey="Diederichs K" first="Kay" last="Diederichs">Kay Diederichs</name>
<affiliation wicri:level="1"><nlm:aff id="a64"><institution>Department of Biology, University of Konstanz</institution>
, D-78457 Konstanz,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Crosas, Merce" sort="Crosas, Merce" uniqKey="Crosas M" first="Mercè" last="Crosas">Mercè Crosas</name>
<affiliation wicri:level="1"><nlm:aff id="a65"><institution>Institute for Quantitative Social Science, Harvard University</institution>
, Cambridge, Massachusetts, 02138,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Sliz, Piotr" sort="Sliz, Piotr" uniqKey="Sliz P" first="Piotr" last="Sliz">Piotr Sliz</name>
<affiliation wicri:level="1"><nlm:aff id="a1"><institution>Department of Biological Chemistry and Molecular Pharmacology</institution>
, Boston, Massachusetts 02115,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">26947396</idno>
<idno type="pmc">4786681</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786681</idno>
<idno type="RBID">PMC:4786681</idno>
<idno type="doi">10.1038/ncomms10882</idno>
<date when="2016">2016</date>
<idno type="wicri:Area/Pmc/Corpus">000144</idno>
<idno type="wicri:Area/Pmc/Curation">000144</idno>
<idno type="wicri:Area/Pmc/Checkpoint">000038</idno>
<idno type="wicri:Area/Ncbi/Merge">000715</idno>
<idno type="wicri:Area/Ncbi/Curation">000715</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">000715</idno>
<idno type="wicri:Area/Main/Merge">000040</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Data publication with the structural biology data grid supports live analysis</title>
<author><name sortKey="Meyer, Peter A" sort="Meyer, Peter A" uniqKey="Meyer P" first="Peter A." last="Meyer">Peter A. Meyer</name>
<affiliation wicri:level="1"><nlm:aff id="a1"><institution>Department of Biological Chemistry and Molecular Pharmacology</institution>
, Boston, Massachusetts 02115,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Socias, Stephanie" sort="Socias, Stephanie" uniqKey="Socias S" first="Stephanie" last="Socias">Stephanie Socias</name>
<affiliation wicri:level="1"><nlm:aff id="a1"><institution>Department of Biological Chemistry and Molecular Pharmacology</institution>
, Boston, Massachusetts 02115,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Key, Jason" sort="Key, Jason" uniqKey="Key J" first="Jason" last="Key">Jason Key</name>
<affiliation wicri:level="1"><nlm:aff id="a1"><institution>Department of Biological Chemistry and Molecular Pharmacology</institution>
, Boston, Massachusetts 02115,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Ransey, Elizabeth" sort="Ransey, Elizabeth" uniqKey="Ransey E" first="Elizabeth" last="Ransey">Elizabeth Ransey</name>
<affiliation wicri:level="1"><nlm:aff id="a1"><institution>Department of Biological Chemistry and Molecular Pharmacology</institution>
, Boston, Massachusetts 02115,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Tjon, Emily C" sort="Tjon, Emily C" uniqKey="Tjon E" first="Emily C." last="Tjon">Emily C. Tjon</name>
<affiliation wicri:level="1"><nlm:aff id="a1"><institution>Department of Biological Chemistry and Molecular Pharmacology</institution>
, Boston, Massachusetts 02115,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Buschiazzo, Alejandro" sort="Buschiazzo, Alejandro" uniqKey="Buschiazzo A" first="Alejandro" last="Buschiazzo">Alejandro Buschiazzo</name>
<affiliation wicri:level="1"><nlm:aff id="a2"><institution>Laboratory of Molecular & Structural Microbiology, Institut Pasteur de Montevideo</institution>
, Montevideo 11400,<country>Uruguay</country>
</nlm:aff>
<country xml:lang="fr">Uruguay</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="a3"><institution>Department of Structural Biology & Chemistry, Institut Pasteur</institution>
, 75015 Paris,<country>France</country>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Lei, Ming" sort="Lei, Ming" uniqKey="Lei M" first="Ming" last="Lei">Ming Lei</name>
<affiliation wicri:level="1"><nlm:aff id="a4"><institution>Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences</institution>
, Shanghai 200031,<country>China</country>
</nlm:aff>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Botka, Chris" sort="Botka, Chris" uniqKey="Botka C" first="Chris" last="Botka">Chris Botka</name>
<affiliation wicri:level="1"><nlm:aff id="a5"><institution>Harvard Medical School</institution>
, Boston, Massachusetts 02115,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Withrow, James" sort="Withrow, James" uniqKey="Withrow J" first="James" last="Withrow">James Withrow</name>
<affiliation wicri:level="1"><nlm:aff id="a6"><institution>NE-CAT and Department of Chemistry and Chemical Biology, Cornell University</institution>
, Building 436E, Argonne National Laboratory, 9700S. Cass Avenue, Argonne, Illinois 60439,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Neau, David" sort="Neau, David" uniqKey="Neau D" first="David" last="Neau">David Neau</name>
<affiliation wicri:level="1"><nlm:aff id="a6"><institution>NE-CAT and Department of Chemistry and Chemical Biology, Cornell University</institution>
, Building 436E, Argonne National Laboratory, 9700S. Cass Avenue, Argonne, Illinois 60439,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Rajashankar, Kanagalaghatta" sort="Rajashankar, Kanagalaghatta" uniqKey="Rajashankar K" first="Kanagalaghatta" last="Rajashankar">Kanagalaghatta Rajashankar</name>
<affiliation wicri:level="1"><nlm:aff id="a6"><institution>NE-CAT and Department of Chemistry and Chemical Biology, Cornell University</institution>
, Building 436E, Argonne National Laboratory, 9700S. Cass Avenue, Argonne, Illinois 60439,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Anderson, Karen S" sort="Anderson, Karen S" uniqKey="Anderson K" first="Karen S." last="Anderson">Karen S. Anderson</name>
<affiliation wicri:level="1"><nlm:aff id="a7"><institution>Departments of Pharmacology and Molecular Biophysics and Biochemistry, Yale University School of Medicine</institution>
, New Haven, Connecticut 06520,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Baxter, Richard H" sort="Baxter, Richard H" uniqKey="Baxter R" first="Richard H." last="Baxter">Richard H. Baxter</name>
<affiliation wicri:level="1"><nlm:aff id="a8"><institution>Department of Chemistry, Molecular Biophysics and Biochemistry, Yale University</institution>
, New Haven, Connecticut 06520,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Blacklow, Stephen C" sort="Blacklow, Stephen C" uniqKey="Blacklow S" first="Stephen C." last="Blacklow">Stephen C. Blacklow</name>
<affiliation wicri:level="1"><nlm:aff id="a1"><institution>Department of Biological Chemistry and Molecular Pharmacology</institution>
, Boston, Massachusetts 02115,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Boggon, Titus J" sort="Boggon, Titus J" uniqKey="Boggon T" first="Titus J." last="Boggon">Titus J. Boggon</name>
<affiliation wicri:level="1"><nlm:aff id="a7"><institution>Departments of Pharmacology and Molecular Biophysics and Biochemistry, Yale University School of Medicine</institution>
, New Haven, Connecticut 06520,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Bonvin, Alexandre M J J" sort="Bonvin, Alexandre M J J" uniqKey="Bonvin A" first="Alexandre M. J. J." last="Bonvin">Alexandre M. J. J. Bonvin</name>
<affiliation wicri:level="1"><nlm:aff id="a9"><institution>Bijvoet Center, Faculty of Science, Utrecht University</institution>
, 3584 CH Utrecht,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Borek, Dominika" sort="Borek, Dominika" uniqKey="Borek D" first="Dominika" last="Borek">Dominika Borek</name>
<affiliation wicri:level="1"><nlm:aff id="a10"><institution>Departments of Biophysics and Biochemistry, University of Texas Southwestern Medical Center</institution>
, Dallas, Texas 75390,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Brett, Tom J" sort="Brett, Tom J" uniqKey="Brett T" first="Tom J." last="Brett">Tom J. Brett</name>
<affiliation wicri:level="1"><nlm:aff id="a11"><institution>Department of Internal Medicine, Washington University School of Medicine</institution>
, St Louis, Missouri 63110,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Caflisch, Amedeo" sort="Caflisch, Amedeo" uniqKey="Caflisch A" first="Amedeo" last="Caflisch">Amedeo Caflisch</name>
<affiliation wicri:level="1"><nlm:aff id="a12"><institution>Department of Biochemistry, University of Zurich</institution>
, CH-8057 Zurich,<country>Switzerland</country>
</nlm:aff>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Chang, Chung I" sort="Chang, Chung I" uniqKey="Chang C" first="Chung-I" last="Chang">Chung-I Chang</name>
<affiliation wicri:level="1"><nlm:aff id="a13"><institution>Institute of Biological Chemistry, Academia Sinica</institution>
, Taipei 11529,<country>Taiwan</country>
</nlm:aff>
<country xml:lang="fr">Taïwan</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Chazin, Walter J" sort="Chazin, Walter J" uniqKey="Chazin W" first="Walter J." last="Chazin">Walter J. Chazin</name>
<affiliation wicri:level="1"><nlm:aff id="a14"><institution>Departments of Biochemistry and Chemistry, Center for Structural Biology, Vanderbilt University</institution>
, Nashville, Tennessee 37232,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Corbett, Kevin D" sort="Corbett, Kevin D" uniqKey="Corbett K" first="Kevin D." last="Corbett">Kevin D. Corbett</name>
<affiliation wicri:level="1"><nlm:aff id="a15"><institution>Ludwig Institute for Cancer Research, San Diego Branch</institution>
, La Jolla, California 92093,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="a16"><institution>Department of Cellular and Molecular Medicine, University of California, San Diego</institution>
, La Jolla, California 92093,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Cosgrove, Michael S" sort="Cosgrove, Michael S" uniqKey="Cosgrove M" first="Michael S." last="Cosgrove">Michael S. Cosgrove</name>
<affiliation wicri:level="1"><nlm:aff id="a17"><institution>Department of Biochemistry and Molecular Biology, SUNY Upstate Medical University</institution>
, Syracuse, New York 13210,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Crosson, Sean" sort="Crosson, Sean" uniqKey="Crosson S" first="Sean" last="Crosson">Sean Crosson</name>
<affiliation wicri:level="1"><nlm:aff id="a18"><institution>Department of Biochemistry and Molecular Biology, University of Chicago</institution>
, Chicago, Illinois 60637,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Dhe Paganon, Sirano" sort="Dhe Paganon, Sirano" uniqKey="Dhe Paganon S" first="Sirano" last="Dhe-Paganon">Sirano Dhe-Paganon</name>
<affiliation wicri:level="1"><nlm:aff id="a19"><institution>Department of Cancer Biology, Dana-Farber Cancer Institute</institution>
, Boston, Massachusetts 02115,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Di Cera, Enrico" sort="Di Cera, Enrico" uniqKey="Di Cera E" first="Enrico" last="Di Cera">Enrico Di Cera</name>
<affiliation wicri:level="1"><nlm:aff id="a20"><institution>Edward A. Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine</institution>
, St Louis, Missouri 63104,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Drennan, Catherine L" sort="Drennan, Catherine L" uniqKey="Drennan C" first="Catherine L." last="Drennan">Catherine L. Drennan</name>
<affiliation wicri:level="1"><nlm:aff id="a21"><institution>Departments of Chemistry and Biology and the Howard Hughes Medical Institute, Massachusetts Institute of Technology</institution>
, Cambridge, Massachusetts 02139,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Eck, Michael J" sort="Eck, Michael J" uniqKey="Eck M" first="Michael J." last="Eck">Michael J. Eck</name>
<affiliation wicri:level="1"><nlm:aff id="a1"><institution>Department of Biological Chemistry and Molecular Pharmacology</institution>
, Boston, Massachusetts 02115,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="a19"><institution>Department of Cancer Biology, Dana-Farber Cancer Institute</institution>
, Boston, Massachusetts 02115,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Eichman, Brandt F" sort="Eichman, Brandt F" uniqKey="Eichman B" first="Brandt F." last="Eichman">Brandt F. Eichman</name>
<affiliation wicri:level="1"><nlm:aff id="a22"><institution>Department of Biological Sciences and Center for Structural Biology, Vanderbilt University</institution>
, Nashville, Tennessee 37235,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Fan, Qing R" sort="Fan, Qing R" uniqKey="Fan Q" first="Qing R." last="Fan">Qing R. Fan</name>
<affiliation wicri:level="1"><nlm:aff id="a23"><institution>Departments of Pharmacology and Pathology and Cell Biology, Columbia University</institution>
, New York, New York 10032,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Ferre D Amare, Adrian R" sort="Ferre D Amare, Adrian R" uniqKey="Ferre D Amare A" first="Adrian R." last="Ferré-D'Amaré">Adrian R. Ferré-D'Amaré</name>
<affiliation wicri:level="1"><nlm:aff id="a24"><institution>Laboratory of RNA Biophysics, National Heart, Lung and Blood Institute, NIH</institution>
, Bethesda, Maryland 20892,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Christopher Fromme, J" sort="Christopher Fromme, J" uniqKey="Christopher Fromme J" first="J." last="Christopher Fromme">J. Christopher Fromme</name>
<affiliation wicri:level="1"><nlm:aff id="a25"><institution>Department of Molecular Biology and Genetics, Weill Institute for Cell and Molecular Biology, Cornell University</institution>
, Ithaca, New York 14853,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Garcia, K Christopher" sort="Garcia, K Christopher" uniqKey="Garcia K" first="K. Christopher" last="Garcia">K. Christopher Garcia</name>
<affiliation wicri:level="1"><nlm:aff id="a26"><institution>Howard Hughes Medical Institute, Stanford University School of Medicine</institution>
, Stanford, California 94305,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="a27"><institution>Department of Molecular and Cellular Physiology, Stanford University School of Medicine</institution>
, Stanford, California 94305,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="a28"><institution>Department of Structural Biology, Stanford University School of Medicine</institution>
, Stanford, California 94305,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Gaudet, Rachelle" sort="Gaudet, Rachelle" uniqKey="Gaudet R" first="Rachelle" last="Gaudet">Rachelle Gaudet</name>
<affiliation wicri:level="1"><nlm:aff id="a29"><institution>Department of Molecular and Cellular Biology, Harvard University</institution>
, Cambridge, Massachusetts 02138,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Gong, Peng" sort="Gong, Peng" uniqKey="Gong P" first="Peng" last="Gong">Peng Gong</name>
<affiliation wicri:level="1"><nlm:aff id="a30"><institution>Key Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virology, Chinese Academy of Sciences</institution>
, Wuhan 430071,<country>China</country>
</nlm:aff>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Harrison, Stephen C" sort="Harrison, Stephen C" uniqKey="Harrison S" first="Stephen C." last="Harrison">Stephen C. Harrison</name>
<affiliation wicri:level="1"><nlm:aff id="a1"><institution>Department of Biological Chemistry and Molecular Pharmacology</institution>
, Boston, Massachusetts 02115,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="a31"><institution>Howard Hughes Medical Institute, Harvard Medical School</institution>
, Boston, Massachusetts 02115,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="a32"><institution>Laboratory of Molecular Medicine, Boston Children's Hospital, Harvard Medical School</institution>
, Boston, Massachusetts 02115,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Heldwein, Ekaterina E" sort="Heldwein, Ekaterina E" uniqKey="Heldwein E" first="Ekaterina E." last="Heldwein">Ekaterina E. Heldwein</name>
<affiliation wicri:level="1"><nlm:aff id="a33"><institution>Department of Molecular Biology and Microbiology, Tufts University School of Medicine</institution>
, Boston, Massachusetts 02111,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Jia, Zongchao" sort="Jia, Zongchao" uniqKey="Jia Z" first="Zongchao" last="Jia">Zongchao Jia</name>
<affiliation wicri:level="1"><nlm:aff id="a34"><institution>Department of Biomedical and Molecular Sciences, Queen's University</institution>
, Kingston, Ontario,<country>Canada</country>
K7M 3G5</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Keenan, Robert J" sort="Keenan, Robert J" uniqKey="Keenan R" first="Robert J." last="Keenan">Robert J. Keenan</name>
<affiliation wicri:level="1"><nlm:aff id="a18"><institution>Department of Biochemistry and Molecular Biology, University of Chicago</institution>
, Chicago, Illinois 60637,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Kruse, Andrew C" sort="Kruse, Andrew C" uniqKey="Kruse A" first="Andrew C." last="Kruse">Andrew C. Kruse</name>
<affiliation wicri:level="1"><nlm:aff id="a1"><institution>Department of Biological Chemistry and Molecular Pharmacology</institution>
, Boston, Massachusetts 02115,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Kvansakul, Marc" sort="Kvansakul, Marc" uniqKey="Kvansakul M" first="Marc" last="Kvansakul">Marc Kvansakul</name>
<affiliation wicri:level="1"><nlm:aff id="a35"><institution>Department of Biochemistry and Genetics, La Trobe University</institution>
, Melbourne, Victoria 3086,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Mclellan, Jason S" sort="Mclellan, Jason S" uniqKey="Mclellan J" first="Jason S." last="Mclellan">Jason S. Mclellan</name>
<affiliation wicri:level="1"><nlm:aff id="a36"><institution>Department of Biochemistry, Geisel School of Medicine at Dartmouth</institution>
, Hanover, New Hampshire 03755,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Modis, Yorgo" sort="Modis, Yorgo" uniqKey="Modis Y" first="Yorgo" last="Modis">Yorgo Modis</name>
<affiliation wicri:level="1"><nlm:aff id="a37"><institution>Department of Medicine, University of Cambridge, MRC Laboratory of Molecular Biology</institution>
, Francis Crick Avenue, Cambridge CB2 0QH,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Nam, Yunsun" sort="Nam, Yunsun" uniqKey="Nam Y" first="Yunsun" last="Nam">Yunsun Nam</name>
<affiliation wicri:level="1"><nlm:aff id="a38"><institution>University of Texas, Southwestern Medical Center</institution>
, Dallas, Texas 75390,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Otwinowski, Zbyszek" sort="Otwinowski, Zbyszek" uniqKey="Otwinowski Z" first="Zbyszek" last="Otwinowski">Zbyszek Otwinowski</name>
<affiliation wicri:level="1"><nlm:aff id="a10"><institution>Departments of Biophysics and Biochemistry, University of Texas Southwestern Medical Center</institution>
, Dallas, Texas 75390,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Pai, Emil F" sort="Pai, Emil F" uniqKey="Pai E" first="Emil F." last="Pai">Emil F. Pai</name>
<affiliation wicri:level="1"><nlm:aff id="a39"><institution>Departments of Biochemistry, Medical Biophysics and Molecular Genetics, University of Toronto</institution>
, Toronto, Ontario,<country>Canada</country>
M5S 1A8</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="a40"><institution>Campbell Family Institute for Cancer Research, Ontario Cancer Institute/University Health Network</institution>
, Toronto, Ontario,<country>Canada</country>
M5G 2M9</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Pereira, Pedro Jose Barbosa" sort="Pereira, Pedro Jose Barbosa" uniqKey="Pereira P" first="Pedro José Barbosa" last="Pereira">Pedro José Barbosa Pereira</name>
<affiliation wicri:level="1"><nlm:aff id="a41"><institution>IBMC—Instituto de Biologia Molecular e Celular and Instituto de Investigação e Inovação em Saúde, Universidade do Porto</institution>
, 4150 Porto,<country>Portugal</country>
</nlm:aff>
<country xml:lang="fr">Portugal</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Petosa, Carlo" sort="Petosa, Carlo" uniqKey="Petosa C" first="Carlo" last="Petosa">Carlo Petosa</name>
<affiliation wicri:level="1"><nlm:aff id="a42"><institution>Université Grenoble Alpes/CNRS/CEA, Institut de Biologie Structurale</institution>
, 38027 Grenoble,<country>France</country>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Raman, C S" sort="Raman, C S" uniqKey="Raman C" first="C. S." last="Raman">C. S. Raman</name>
<affiliation wicri:level="1"><nlm:aff id="a43"><institution>Department of Pharmaceutical Sciences, University of Maryland</institution>
, Baltimore, Maryland 21201,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Rapoport, Tom A" sort="Rapoport, Tom A" uniqKey="Rapoport T" first="Tom A." last="Rapoport">Tom A. Rapoport</name>
<affiliation wicri:level="1"><nlm:aff id="a44"><institution>Howard Hughes Medical Institute and Harvard Medical School, Department of Cell Biology</institution>
, Boston, Massachusetts 02115,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Roll Mecak, Antonina" sort="Roll Mecak, Antonina" uniqKey="Roll Mecak A" first="Antonina" last="Roll-Mecak">Antonina Roll-Mecak</name>
<affiliation wicri:level="1"><nlm:aff id="a45"><institution>Cell Biology and Biophysics Unit, Porter Neuroscience Research Center, National Institute of Neurological Disorders and Stroke</institution>
, Bethesda, Maryland 20892,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="a46"><institution>National Heart, Lung and Blood Institute</institution>
, Bethesda, Maryland 20892,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Rosen, Michael K" sort="Rosen, Michael K" uniqKey="Rosen M" first="Michael K." last="Rosen">Michael K. Rosen</name>
<affiliation wicri:level="1"><nlm:aff id="a47"><institution>Department of Biophysics and Howard Hughes Medical Institute, University of Texas Southwestern Medical Center</institution>
, Dallas, Texas 75390,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Rudenko, Gabby" sort="Rudenko, Gabby" uniqKey="Rudenko G" first="Gabby" last="Rudenko">Gabby Rudenko</name>
<affiliation wicri:level="1"><nlm:aff id="a48"><institution>Department of Pharmacology and Toxicology, Sealy Center for Structural Biology and Molecular Biophysics, University of Texas Medical Branch</institution>
, Galveston, Texas 77555,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Schlessinger, Joseph" sort="Schlessinger, Joseph" uniqKey="Schlessinger J" first="Joseph" last="Schlessinger">Joseph Schlessinger</name>
<affiliation wicri:level="1"><nlm:aff id="a49"><institution>Department of Pharmacology, Yale University School of Medicine</institution>
, New Haven, Connecticut 06520,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Schwartz, Thomas U" sort="Schwartz, Thomas U" uniqKey="Schwartz T" first="Thomas U." last="Schwartz">Thomas U. Schwartz</name>
<affiliation wicri:level="1"><nlm:aff id="a50"><institution>Department of Biology, Massachusetts Institute of Technology</institution>
, Cambridge, Massachusetts 02139,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Shamoo, Yousif" sort="Shamoo, Yousif" uniqKey="Shamoo Y" first="Yousif" last="Shamoo">Yousif Shamoo</name>
<affiliation wicri:level="1"><nlm:aff id="a51"><institution>Department of BioSciences, Rice University</institution>
, Houston, Texas 77005,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Sondermann, Holger" sort="Sondermann, Holger" uniqKey="Sondermann H" first="Holger" last="Sondermann">Holger Sondermann</name>
<affiliation wicri:level="1"><nlm:aff id="a52"><institution>Department of Molecular Medicine, College of Veterinary Medicine, Cornell University</institution>
, Ithaca, New York 14853,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Tao, Yizhi J" sort="Tao, Yizhi J" uniqKey="Tao Y" first="Yizhi J." last="Tao">Yizhi J. Tao</name>
<affiliation wicri:level="1"><nlm:aff id="a51"><institution>Department of BioSciences, Rice University</institution>
, Houston, Texas 77005,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Tolia, Niraj H" sort="Tolia, Niraj H" uniqKey="Tolia N" first="Niraj H." last="Tolia">Niraj H. Tolia</name>
<affiliation wicri:level="1"><nlm:aff id="a53"><institution>Department of Molecular Microbiology, Washington University School of Medicine</institution>
, St Louis, Missouri 63110,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Tsodikov, Oleg V" sort="Tsodikov, Oleg V" uniqKey="Tsodikov O" first="Oleg V." last="Tsodikov">Oleg V. Tsodikov</name>
<affiliation wicri:level="1"><nlm:aff id="a54"><institution>Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky</institution>
, Lexington, Kentucky 40536,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Westover, Kenneth D" sort="Westover, Kenneth D" uniqKey="Westover K" first="Kenneth D." last="Westover">Kenneth D. Westover</name>
<affiliation wicri:level="1"><nlm:aff id="a55"><institution>Departments of Biochemistry and Radiation Oncology, University of Texas, Southwestern Medical Center</institution>
, Dallas, Texas 75390,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Wu, Hao" sort="Wu, Hao" uniqKey="Wu H" first="Hao" last="Wu">Hao Wu</name>
<affiliation wicri:level="1"><nlm:aff id="a1"><institution>Department of Biological Chemistry and Molecular Pharmacology</institution>
, Boston, Massachusetts 02115,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="a56"><institution>Program in Cellular and Molecular Medicine, Boston Children's Hospital</institution>
, Boston, Massachusetts 02115,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Foster, Ian" sort="Foster, Ian" uniqKey="Foster I" first="Ian" last="Foster">Ian Foster</name>
<affiliation wicri:level="1"><nlm:aff id="a57"><institution>Mathematics and Computer Science Division, Argonne National Laboratory, Argonne, Illinois, and Department of Computer Science, University of Chicago</institution>
, Chicago, Illinois 60637,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Fraser, James S" sort="Fraser, James S" uniqKey="Fraser J" first="James S." last="Fraser">James S. Fraser</name>
<affiliation wicri:level="1"><nlm:aff id="a58"><institution>Department of Bioengineering and Therapeutic Sciences, University of California San Francisco</institution>
, San Francisco, California 94158,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Maia, Filipe R N C" sort="Maia, Filipe R N C" uniqKey="Maia F" first="Filipe R. N C." last="Maia">Filipe R. N C. Maia</name>
<affiliation wicri:level="1"><nlm:aff id="a59"><institution>Laboratory of Molecular Biophysics, Department of Cell and Molecular Biology, Uppsala University</institution>
, Husargatan 3 (Box 596), SE-751 24 Uppsala,<country>Sweden</country>
</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="a60"><institution>NERSC, Lawrence Berkeley National Laboratory</institution>
, Berkeley, California 94720,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Gonen, Tamir" sort="Gonen, Tamir" uniqKey="Gonen T" first="Tamir" last="Gonen">Tamir Gonen</name>
<affiliation wicri:level="1"><nlm:aff id="a61"><institution>Janelia Research Campus, Howard Hughes Medical Institute</institution>
, Ashburn, Virginia 20147<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Kirchhausen, Tom" sort="Kirchhausen, Tom" uniqKey="Kirchhausen T" first="Tom" last="Kirchhausen">Tom Kirchhausen</name>
<affiliation wicri:level="1"><nlm:aff id="a62"><institution>Program in Cellular and Molecular Medicine and Department of Pediatrics, Boston Children's Hospital</institution>
, Boston, Massachusetts 02115,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="a63"><institution>Departments of Cell Biology, Harvard Medical School</institution>
, Boston, Massachusetts 02115,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Diederichs, Kay" sort="Diederichs, Kay" uniqKey="Diederichs K" first="Kay" last="Diederichs">Kay Diederichs</name>
<affiliation wicri:level="1"><nlm:aff id="a64"><institution>Department of Biology, University of Konstanz</institution>
, D-78457 Konstanz,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Crosas, Merce" sort="Crosas, Merce" uniqKey="Crosas M" first="Mercè" last="Crosas">Mercè Crosas</name>
<affiliation wicri:level="1"><nlm:aff id="a65"><institution>Institute for Quantitative Social Science, Harvard University</institution>
, Cambridge, Massachusetts, 02138,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Sliz, Piotr" sort="Sliz, Piotr" uniqKey="Sliz P" first="Piotr" last="Sliz">Piotr Sliz</name>
<affiliation wicri:level="1"><nlm:aff id="a1"><institution>Department of Biological Chemistry and Molecular Pharmacology</institution>
, Boston, Massachusetts 02115,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
</analytic>
<series><title level="j">Nature Communications</title>
<idno type="eISSN">2041-1723</idno>
<imprint><date when="2016">2016</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><p>Access to experimental X-ray diffraction image data is fundamental for validation and reproduction of macromolecular models and indispensable for development of structural biology processing methods. Here, we established a diffraction data publication and dissemination system, Structural Biology Data Grid (SBDG; data.sbgrid.org), to preserve primary experimental data sets that support scientific publications. Data sets are accessible to researchers through a community driven data grid, which facilitates global data access. Our analysis of a pilot collection of crystallographic data sets demonstrates that the information archived by SBDG is sufficient to reprocess data to statistics that meet or exceed the quality of the original published structures. SBDG has extended its services to the entire community and is used to develop support for other types of biomedical data sets. It is anticipated that access to the experimental data sets will enhance the paradigm shift in the community towards a much more dynamic body of continuously improving data analysis.</p>
</div>
</front>
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