Toward an Integrated RNA Motif Database
Identifieur interne : 000218 ( Istex/Corpus ); précédent : 000217; suivant : 000219Toward an Integrated RNA Motif Database
Auteurs : L. Wang ; Dongrong Wen ; A. Shapiro ; G. Herbert ; Jing Li ; Kaushik GhoshSource :
- Lecture Notes in Computer Science [ 0302-9743 ] ; 2007.
Abstract
Abstract: In this paper we present the design and implementation of an RNA structural motif database, called RmotifDB. The structural motifs stored in RmotifDB come from three sources: (1) collected manually from biomedical literature; (2) submitted by scientists around the world; and (3) discovered by a wide variety of motif mining methods. We present here a motif mining method in detail. We also describe the interface and search mechanisms provided by RmotifDB as well as techniques used to integrate RmotifDB with the Gene Ontology. The RmotifDB system is fully operational and accessible on the Internet at http://datalab.njit.edu/bioinfo/
Url:
DOI: 10.1007/978-3-540-73255-6_5
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<Affiliation ID="Aff1"><OrgName>Bioinformatics Program and Department of Computer Science, New Jersey Institute of Technology, Newark, NJ 07102</OrgName>
<OrgAddress><Country> </Country>
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<Affiliation ID="Aff2"><OrgName>Center for Cancer Research Nanobiology Program, National Cancer Institute, Frederick, MD 21702</OrgName>
<OrgAddress><Country> </Country>
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<Affiliation ID="Aff3"><OrgName>Department of Computer Science, Montclair State University, Montclair, NJ 07043</OrgName>
<OrgAddress><Country> </Country>
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<Para>In this paper we present the design and implementation of an RNA structural motif database, called RmotifDB. The structural motifs stored in RmotifDB come from three sources: (1) collected manually from biomedical literature; (2) submitted by scientists around the world; and (3) discovered by a wide variety of motif mining methods. We present here a motif mining method in detail. We also describe the interface and search mechanisms provided by RmotifDB as well as techniques used to integrate RmotifDB with the Gene Ontology. The RmotifDB system is fully operational and accessible on the Internet at http://datalab.njit.edu/bioinfo/</Para>
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<abstract lang="en">Abstract: In this paper we present the design and implementation of an RNA structural motif database, called RmotifDB. The structural motifs stored in RmotifDB come from three sources: (1) collected manually from biomedical literature; (2) submitted by scientists around the world; and (3) discovered by a wide variety of motif mining methods. We present here a motif mining method in detail. We also describe the interface and search mechanisms provided by RmotifDB as well as techniques used to integrate RmotifDB with the Gene Ontology. The RmotifDB system is fully operational and accessible on the Internet at http://datalab.njit.edu/bioinfo/</abstract>
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