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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Dietary Quality and 6-Year Anthropometric Changes in a Sample of French Middle-Aged Overweight and Obese Adults</title>
<author><name sortKey="Assmann, Karen E" sort="Assmann, Karen E" uniqKey="Assmann K" first="Karen E." last="Assmann">Karen E. Assmann</name>
<affiliation><nlm:aff id="aff1"><addr-line>Université Paris 13 Sorbonne Paris Cité, UREN (Nutritional Epidemiology Research Unit), Inserm (U557), Inra (U1125), Cnam, Bobigny, France</addr-line>
</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Lassale, Camille" sort="Lassale, Camille" uniqKey="Lassale C" first="Camille" last="Lassale">Camille Lassale</name>
<affiliation><nlm:aff id="aff1"><addr-line>Université Paris 13 Sorbonne Paris Cité, UREN (Nutritional Epidemiology Research Unit), Inserm (U557), Inra (U1125), Cnam, Bobigny, France</addr-line>
</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Galan, Pilar" sort="Galan, Pilar" uniqKey="Galan P" first="Pilar" last="Galan">Pilar Galan</name>
<affiliation><nlm:aff id="aff1"><addr-line>Université Paris 13 Sorbonne Paris Cité, UREN (Nutritional Epidemiology Research Unit), Inserm (U557), Inra (U1125), Cnam, Bobigny, France</addr-line>
</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Hercberg, Serge" sort="Hercberg, Serge" uniqKey="Hercberg S" first="Serge" last="Hercberg">Serge Hercberg</name>
<affiliation><nlm:aff id="aff1"><addr-line>Université Paris 13 Sorbonne Paris Cité, UREN (Nutritional Epidemiology Research Unit), Inserm (U557), Inra (U1125), Cnam, Bobigny, France</addr-line>
</nlm:aff>
</affiliation>
<affiliation><nlm:aff id="aff2"><addr-line>Département de Santé Publique, Hôpital Avicenne, Bobigny, France</addr-line>
</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Kesse Guyot, Emmanuelle" sort="Kesse Guyot, Emmanuelle" uniqKey="Kesse Guyot E" first="Emmanuelle" last="Kesse-Guyot">Emmanuelle Kesse-Guyot</name>
<affiliation><nlm:aff id="aff1"><addr-line>Université Paris 13 Sorbonne Paris Cité, UREN (Nutritional Epidemiology Research Unit), Inserm (U557), Inra (U1125), Cnam, Bobigny, France</addr-line>
</nlm:aff>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">24516542</idno>
<idno type="pmc">3916323</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916323</idno>
<idno type="RBID">PMC:3916323</idno>
<idno type="doi">10.1371/journal.pone.0087083</idno>
<date when="2014">2014</date>
<idno type="wicri:Area/Pmc/Corpus">000525</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000525</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Dietary Quality and 6-Year Anthropometric Changes in a Sample of French Middle-Aged Overweight and Obese Adults</title>
<author><name sortKey="Assmann, Karen E" sort="Assmann, Karen E" uniqKey="Assmann K" first="Karen E." last="Assmann">Karen E. Assmann</name>
<affiliation><nlm:aff id="aff1"><addr-line>Université Paris 13 Sorbonne Paris Cité, UREN (Nutritional Epidemiology Research Unit), Inserm (U557), Inra (U1125), Cnam, Bobigny, France</addr-line>
</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Lassale, Camille" sort="Lassale, Camille" uniqKey="Lassale C" first="Camille" last="Lassale">Camille Lassale</name>
<affiliation><nlm:aff id="aff1"><addr-line>Université Paris 13 Sorbonne Paris Cité, UREN (Nutritional Epidemiology Research Unit), Inserm (U557), Inra (U1125), Cnam, Bobigny, France</addr-line>
</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Galan, Pilar" sort="Galan, Pilar" uniqKey="Galan P" first="Pilar" last="Galan">Pilar Galan</name>
<affiliation><nlm:aff id="aff1"><addr-line>Université Paris 13 Sorbonne Paris Cité, UREN (Nutritional Epidemiology Research Unit), Inserm (U557), Inra (U1125), Cnam, Bobigny, France</addr-line>
</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Hercberg, Serge" sort="Hercberg, Serge" uniqKey="Hercberg S" first="Serge" last="Hercberg">Serge Hercberg</name>
<affiliation><nlm:aff id="aff1"><addr-line>Université Paris 13 Sorbonne Paris Cité, UREN (Nutritional Epidemiology Research Unit), Inserm (U557), Inra (U1125), Cnam, Bobigny, France</addr-line>
</nlm:aff>
</affiliation>
<affiliation><nlm:aff id="aff2"><addr-line>Département de Santé Publique, Hôpital Avicenne, Bobigny, France</addr-line>
</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Kesse Guyot, Emmanuelle" sort="Kesse Guyot, Emmanuelle" uniqKey="Kesse Guyot E" first="Emmanuelle" last="Kesse-Guyot">Emmanuelle Kesse-Guyot</name>
<affiliation><nlm:aff id="aff1"><addr-line>Université Paris 13 Sorbonne Paris Cité, UREN (Nutritional Epidemiology Research Unit), Inserm (U557), Inra (U1125), Cnam, Bobigny, France</addr-line>
</nlm:aff>
</affiliation>
</author>
</analytic>
<series><title level="j">PLoS ONE</title>
<idno type="eISSN">1932-6203</idno>
<imprint><date when="2014">2014</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><sec><title>Background</title>
<p>Understanding the role of dietary quality in the progression of adiposity in populations already affected by overweight or obesity is crucial for the guidance of secondary prevention strategies.</p>
</sec>
<sec><title>Objective</title>
<p>To examine the association of diet quality, as reflected by the French Nutrition and Health Programme (Programme National Nutrition Santé, PNNS) – Guideline Score (GS), with 6-year-changes in weight and waist circumference.</p>
</sec>
<sec><title>Design and Methods</title>
<p>Subjects were 1029 male and 450 female participants of the SUplémentation en VItamines et Minéraux AntioXydants (SU.VI.MAX) cohort (1994–2002) with anthropometric variables at baseline and follow-up and available data for estimating diet quality at baseline. We employed analysis of variance and covariance models to investigate anthropometric changes (% of the initial value) by categories of the PNNS-GS, which contains both dietary components and a physical activity component, and of a modified score (mPNNS-GS) containing dietary components only.</p>
</sec>
<sec><title>Results</title>
<p>In men, a low (<6 points) PNNS-GS was associated with greater 6-year weight gain (adjusted mean: 3.63% [95% confidence interval: 2.87%; 4.39%]) as compared to a high (≥9 points) PNNS-GS (2.10% [1.39%; 2.81%]); p = 0.01. Results for the mPNNS-GS were very similar. In women, no associations between diet scores and weight change were observed. No significant relation between dietary quality and change in waist circumference was present among either men or women.</p>
</sec>
<sec><title>Conclusions</title>
<p>These results support a beneficial role of high dietary quality – as characterized by good adherence to official French nutritional guidelines – in secondary obesity prevention, among men.</p>
</sec>
</div>
</front>
<back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Malik, Vs" uniqKey="Malik V">VS Malik</name>
</author>
<author><name sortKey="Willett, Wc" uniqKey="Willett W">WC Willett</name>
</author>
<author><name sortKey="Hu, Fb" uniqKey="Hu F">FB Hu</name>
</author>
</analytic>
</biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct><analytic><author><name sortKey="Painter, J" uniqKey="Painter J">J Painter</name>
</author>
<author><name sortKey="Rah, Jh" uniqKey="Rah J">JH Rah</name>
</author>
<author><name sortKey="Lee, Yk" uniqKey="Lee Y">YK Lee</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Bull, Fc" uniqKey="Bull F">FC Bull</name>
</author>
<author><name sortKey="Bellew, B" uniqKey="Bellew B">B Bellew</name>
</author>
<author><name sortKey="Schoppe, S" uniqKey="Schoppe S">S Schöppe</name>
</author>
<author><name sortKey="Bauman, Ae" uniqKey="Bauman A">AE Bauman</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Hercberg, S" uniqKey="Hercberg S">S Hercberg</name>
</author>
<author><name sortKey="Chat Yung, S" uniqKey="Chat Yung S">S Chat-Yung</name>
</author>
<author><name sortKey="Chauliac, M" uniqKey="Chauliac M">M Chauliac</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Hu, Fb" uniqKey="Hu F">FB Hu</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Waijers, Pmcm" uniqKey="Waijers P">PMCM Waijers</name>
</author>
<author><name sortKey="Feskens, Ejm" uniqKey="Feskens E">EJM Feskens</name>
</author>
<author><name sortKey="Ocke, Mc" uniqKey="Ocke M">MC Ocke</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Wirt, A" uniqKey="Wirt A">A Wirt</name>
</author>
<author><name sortKey="Collins, Ce" uniqKey="Collins C">CE Collins</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Beunza, Jj" uniqKey="Beunza J">JJ Beunza</name>
</author>
<author><name sortKey="Toledo, E" uniqKey="Toledo E">E Toledo</name>
</author>
<author><name sortKey="Hu, Fb" uniqKey="Hu F">FB Hu</name>
</author>
<author><name sortKey="Rastrollo, Mb" uniqKey="Rastrollo M">MB Rastrollo</name>
</author>
<author><name sortKey="Martinez, Ms" uniqKey="Martinez M">MS Martinez</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Gao, Sk" uniqKey="Gao S">SK Gao</name>
</author>
<author><name sortKey="Beresford, Saa" uniqKey="Beresford S">SAA Beresford</name>
</author>
<author><name sortKey="Frank, Ll" uniqKey="Frank L">LL Frank</name>
</author>
<author><name sortKey="Schreiner, Pj" uniqKey="Schreiner P">PJ Schreiner</name>
</author>
<author><name sortKey="Burke, Gl" uniqKey="Burke G">GL Burke</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Arabshahi, S" uniqKey="Arabshahi S">S Arabshahi</name>
</author>
<author><name sortKey="Van Der Pols, Jc" uniqKey="Van Der Pols J">JC van der Pols</name>
</author>
<author><name sortKey="Williams, Gm" uniqKey="Williams G">GM Williams</name>
</author>
<author><name sortKey="Marks, Gc" uniqKey="Marks G">GC Marks</name>
</author>
<author><name sortKey="Lahmann, Ph" uniqKey="Lahmann P">PH Lahmann</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Kimokoti, Rw" uniqKey="Kimokoti R">RW Kimokoti</name>
</author>
<author><name sortKey="Newby, Pk" uniqKey="Newby P">PK Newby</name>
</author>
<author><name sortKey="Gona, P" uniqKey="Gona P">P Gona</name>
</author>
<author><name sortKey="Zhu, L" uniqKey="Zhu L">L Zhu</name>
</author>
<author><name sortKey="Jasuja, Gk" uniqKey="Jasuja G">GK Jasuja</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Quatromoni, Pa" uniqKey="Quatromoni P">PA Quatromoni</name>
</author>
<author><name sortKey="Pencina, M" uniqKey="Pencina M">M Pencina</name>
</author>
<author><name sortKey="Cobain, Mr" uniqKey="Cobain M">MR Cobain</name>
</author>
<author><name sortKey="Jacques, Pf" uniqKey="Jacques P">PF Jacques</name>
</author>
<author><name sortKey="D Agostino, Rb" uniqKey="D Agostino R">RB D'Agostino</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Zamora, D" uniqKey="Zamora D">D Zamora</name>
</author>
<author><name sortKey="Gordon Larsen, P" uniqKey="Gordon Larsen P">P Gordon-Larsen</name>
</author>
<author><name sortKey="Jacobs, Dr" uniqKey="Jacobs D">DR Jacobs</name>
</author>
<author><name sortKey="Popkin, Bm" uniqKey="Popkin B">BM Popkin</name>
</author>
</analytic>
</biblStruct>
<biblStruct></biblStruct>
<biblStruct><analytic><author><name sortKey="Wolongevicz, Dm" uniqKey="Wolongevicz D">DM Wolongevicz</name>
</author>
<author><name sortKey="Zhu, L" uniqKey="Zhu L">L Zhu</name>
</author>
<author><name sortKey="Pencina, Mj" uniqKey="Pencina M">MJ Pencina</name>
</author>
<author><name sortKey="Kimokoti, Rw" uniqKey="Kimokoti R">RW Kimokoti</name>
</author>
<author><name sortKey="Newby, Pk" uniqKey="Newby P">PK Newby</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Lassale, C" uniqKey="Lassale C">C Lassale</name>
</author>
<author><name sortKey="Fezeu, L" uniqKey="Fezeu L">L Fezeu</name>
</author>
<author><name sortKey="Andreeva, Va" uniqKey="Andreeva V">VA Andreeva</name>
</author>
<author><name sortKey="Hercberg, S" uniqKey="Hercberg S">S Hercberg</name>
</author>
<author><name sortKey="Kengne, Ap" uniqKey="Kengne A">AP Kengne</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Kesse Guyot, E" uniqKey="Kesse Guyot E">E Kesse-Guyot</name>
</author>
<author><name sortKey="Castetbon, K" uniqKey="Castetbon K">K Castetbon</name>
</author>
<author><name sortKey="Estaquio, C" uniqKey="Estaquio C">C Estaquio</name>
</author>
<author><name sortKey="Czernichow, S" uniqKey="Czernichow S">S Czernichow</name>
</author>
<author><name sortKey="Galan, P" uniqKey="Galan P">P Galan</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Hercberg, S" uniqKey="Hercberg S">S Hercberg</name>
</author>
<author><name sortKey="Galan, P" uniqKey="Galan P">P Galan</name>
</author>
<author><name sortKey="Preziosi, P" uniqKey="Preziosi P">P Preziosi</name>
</author>
<author><name sortKey="Bertrais, S" uniqKey="Bertrais S">S Bertrais</name>
</author>
<author><name sortKey="Mennen, L" uniqKey="Mennen L">L Mennen</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Le Moullec, N" uniqKey="Le Moullec N">N Le Moullec</name>
</author>
<author><name sortKey="Deheeger, M" uniqKey="Deheeger M">M Deheeger</name>
</author>
<author><name sortKey="Preziosi, P" uniqKey="Preziosi P">P Preziosi</name>
</author>
<author><name sortKey="Monteiro, P" uniqKey="Monteiro P">P Monteiro</name>
</author>
<author><name sortKey="Valeix, P" uniqKey="Valeix P">P Valeix</name>
</author>
</analytic>
</biblStruct>
<biblStruct></biblStruct>
<biblStruct><analytic><author><name sortKey="Mennen, Li" uniqKey="Mennen L">LI Mennen</name>
</author>
<author><name sortKey="Bertrais, S" uniqKey="Bertrais S">S Bertrais</name>
</author>
<author><name sortKey="Galan, P" uniqKey="Galan P">P Galan</name>
</author>
<author><name sortKey="Arnault, N" uniqKey="Arnault N">N Arnault</name>
</author>
<author><name sortKey="De Couray, Gp" uniqKey="De Couray G">GP de Couray</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Lasfargues, G" uniqKey="Lasfargues G">G Lasfargues</name>
</author>
<author><name sortKey="Vol, S" uniqKey="Vol S">S Vol</name>
</author>
<author><name sortKey="Leclesiau, H" uniqKey="Leclesiau H">H Leclesiau</name>
</author>
<author><name sortKey="Bedouet, M" uniqKey="Bedouet M">M Bedouet</name>
</author>
<author><name sortKey="Hagel, L" uniqKey="Hagel L">L Hagel</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Vuillemin, A" uniqKey="Vuillemin A">A Vuillemin</name>
</author>
<author><name sortKey="Oppert, Jm" uniqKey="Oppert J">JM Oppert</name>
</author>
<author><name sortKey="Guillemin, F" uniqKey="Guillemin F">F Guillemin</name>
</author>
<author><name sortKey="Essermeant, L" uniqKey="Essermeant L">L Essermeant</name>
</author>
<author><name sortKey="Fontvieille, Am" uniqKey="Fontvieille A">AM Fontvieille</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Schulz, Lo" uniqKey="Schulz L">LO Schulz</name>
</author>
<author><name sortKey="Harper, It" uniqKey="Harper I">IT Harper</name>
</author>
<author><name sortKey="Smith, Cj" uniqKey="Smith C">CJ Smith</name>
</author>
<author><name sortKey="Kriska, Am" uniqKey="Kriska A">AM Kriska</name>
</author>
<author><name sortKey="Ravussin, E" uniqKey="Ravussin E">E Ravussin</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Kriska, Am" uniqKey="Kriska A">AM Kriska</name>
</author>
<author><name sortKey="Knowler, Wc" uniqKey="Knowler W">WC Knowler</name>
</author>
<author><name sortKey="Laporte, Re" uniqKey="Laporte R">RE LaPorte</name>
</author>
<author><name sortKey="Drash, Al" uniqKey="Drash A">AL Drash</name>
</author>
<author><name sortKey="Wing, Rr" uniqKey="Wing R">RR Wing</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Ainsworth, Be" uniqKey="Ainsworth B">BE Ainsworth</name>
</author>
<author><name sortKey="Haskell, Wl" uniqKey="Haskell W">WL Haskell</name>
</author>
<author><name sortKey="Whitt, Mc" uniqKey="Whitt M">MC Whitt</name>
</author>
<author><name sortKey="Irwin, Ml" uniqKey="Irwin M">ML Irwin</name>
</author>
<author><name sortKey="Swartz, Am" uniqKey="Swartz A">AM Swartz</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Ainsworth, Be" uniqKey="Ainsworth B">BE Ainsworth</name>
</author>
<author><name sortKey="Haskell, Wl" uniqKey="Haskell W">WL Haskell</name>
</author>
<author><name sortKey="Leon, As" uniqKey="Leon A">AS Leon</name>
</author>
<author><name sortKey="Jacobs, Dr" uniqKey="Jacobs D">DR Jacobs</name>
</author>
<author><name sortKey="Montoye, Hj" uniqKey="Montoye H">HJ Montoye</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Lairon, D" uniqKey="Lairon D">D Lairon</name>
</author>
<author><name sortKey="Arnault, N" uniqKey="Arnault N">N Arnault</name>
</author>
<author><name sortKey="Bertrais, S" uniqKey="Bertrais S">S Bertrais</name>
</author>
<author><name sortKey="Planells, R" uniqKey="Planells R">R Planells</name>
</author>
<author><name sortKey="Clero, E" uniqKey="Clero E">E Clero</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Estaquio, C" uniqKey="Estaquio C">C Estaquio</name>
</author>
<author><name sortKey="Kesse Guyot, E" uniqKey="Kesse Guyot E">E Kesse-Guyot</name>
</author>
<author><name sortKey="Deschamps, V" uniqKey="Deschamps V">V Deschamps</name>
</author>
<author><name sortKey="Bertrais, S" uniqKey="Bertrais S">S Bertrais</name>
</author>
<author><name sortKey="Dauchet, L" uniqKey="Dauchet L">L Dauchet</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Schofield, Wn" uniqKey="Schofield W">WN Schofield</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Dunnett, Cw" uniqKey="Dunnett C">CW Dunnett</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Newby, Pk" uniqKey="Newby P">PK Newby</name>
</author>
<author><name sortKey="Weismayer, C" uniqKey="Weismayer C">C Weismayer</name>
</author>
<author><name sortKey="Akesson, A" uniqKey="Akesson A">A Akesson</name>
</author>
<author><name sortKey="Tucker, Kl" uniqKey="Tucker K">KL Tucker</name>
</author>
<author><name sortKey="Wolk, A" uniqKey="Wolk A">A Wolk</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Nakade, M" uniqKey="Nakade M">M Nakade</name>
</author>
<author><name sortKey="Lee, Js" uniqKey="Lee J">JS Lee</name>
</author>
<author><name sortKey="Kawakubo, K" uniqKey="Kawakubo K">K Kawakubo</name>
</author>
<author><name sortKey="Kondo, K" uniqKey="Kondo K">K Kondo</name>
</author>
<author><name sortKey="Mori, K" uniqKey="Mori K">K Mori</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Newby, Pk" uniqKey="Newby P">PK Newby</name>
</author>
<author><name sortKey="Muller, D" uniqKey="Muller D">D Muller</name>
</author>
<author><name sortKey="Hallfrisch, J" uniqKey="Hallfrisch J">J Hallfrisch</name>
</author>
<author><name sortKey="Andres, R" uniqKey="Andres R">R Andres</name>
</author>
<author><name sortKey="Tucker, Kl" uniqKey="Tucker K">KL Tucker</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Schulze, Mb" uniqKey="Schulze M">MB Schulze</name>
</author>
<author><name sortKey="Fung, Tt" uniqKey="Fung T">TT Fung</name>
</author>
<author><name sortKey="Manson, Je" uniqKey="Manson J">JE Manson</name>
</author>
<author><name sortKey="Willett, Wc" uniqKey="Willett W">WC Willett</name>
</author>
<author><name sortKey="Hu, Fb" uniqKey="Hu F">FB Hu</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Newby, P" uniqKey="Newby P">P Newby</name>
</author>
<author><name sortKey="Muller, D" uniqKey="Muller D">D Muller</name>
</author>
<author><name sortKey="Hallfrisch, J" uniqKey="Hallfrisch J">J Hallfrisch</name>
</author>
<author><name sortKey="Qiao, N" uniqKey="Qiao N">N Qiao</name>
</author>
<author><name sortKey="Andres, R" uniqKey="Andres R">R Andres</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Black, Ae" uniqKey="Black A">AE Black</name>
</author>
</analytic>
</biblStruct>
<biblStruct></biblStruct>
<biblStruct><analytic><author><name sortKey="Timperio, A" uniqKey="Timperio A">A Timperio</name>
</author>
<author><name sortKey="Cameron Smith, D" uniqKey="Cameron Smith D">D Cameron-Smith</name>
</author>
<author><name sortKey="Burns, C" uniqKey="Burns C">C Burns</name>
</author>
<author><name sortKey="Crawford, D" uniqKey="Crawford D">D Crawford</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Ulijaszek, Sj" uniqKey="Ulijaszek S">SJ Ulijaszek</name>
</author>
<author><name sortKey="Kerr, Da" uniqKey="Kerr D">DA Kerr</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Nordhamn, K" uniqKey="Nordhamn K">K Nordhamn</name>
</author>
<author><name sortKey="Sodergren, E" uniqKey="Sodergren E">E Sodergren</name>
</author>
<author><name sortKey="Olsson, E" uniqKey="Olsson E">E Olsson</name>
</author>
<author><name sortKey="Karlstrom, B" uniqKey="Karlstrom B">B Karlstrom</name>
</author>
<author><name sortKey="Vessby, B" uniqKey="Vessby B">B Vessby</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Resnick, He" uniqKey="Resnick H">HE Resnick</name>
</author>
<author><name sortKey="Valsania, P" uniqKey="Valsania P">P Valsania</name>
</author>
<author><name sortKey="Halter, Jb" uniqKey="Halter J">JB Halter</name>
</author>
<author><name sortKey="Lin, X" uniqKey="Lin X">X Lin</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Czernichow, S" uniqKey="Czernichow S">S Czernichow</name>
</author>
<author><name sortKey="Mennen, L" uniqKey="Mennen L">L Mennen</name>
</author>
<author><name sortKey="Bertrais, S" uniqKey="Bertrais S">S Bertrais</name>
</author>
<author><name sortKey="Preziosi, P" uniqKey="Preziosi P">P Preziosi</name>
</author>
<author><name sortKey="Hercberg, S" uniqKey="Hercberg S">S Hercberg</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Seaman, Sr" uniqKey="Seaman S">SR Seaman</name>
</author>
<author><name sortKey="White, Ir" uniqKey="White I">IR White</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Shen, C" uniqKey="Shen C">C Shen</name>
</author>
<author><name sortKey="Li, X" uniqKey="Li X">X Li</name>
</author>
<author><name sortKey="Li, L" uniqKey="Li L">L Li</name>
</author>
<author><name sortKey="Were, Mc" uniqKey="Were M">MC Were</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Hofler, M" uniqKey="Hofler M">M Hofler</name>
</author>
<author><name sortKey="Pfister, H" uniqKey="Pfister H">H Pfister</name>
</author>
<author><name sortKey="Lieb, R" uniqKey="Lieb R">R Lieb</name>
</author>
<author><name sortKey="Wittchen, Hu" uniqKey="Wittchen H">HU Wittchen</name>
</author>
</analytic>
</biblStruct>
<biblStruct></biblStruct>
<biblStruct><analytic><author><name sortKey="Connor Gorber, S" uniqKey="Connor Gorber S">S Connor Gorber</name>
</author>
<author><name sortKey="Tremblay, M" uniqKey="Tremblay M">M Tremblay</name>
</author>
<author><name sortKey="Moher, D" uniqKey="Moher D">D Moher</name>
</author>
<author><name sortKey="Gorber, B" uniqKey="Gorber B">B Gorber</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Ma, Y" uniqKey="Ma Y">Y Ma</name>
</author>
<author><name sortKey="Olendzki, Bc" uniqKey="Olendzki B">BC Olendzki</name>
</author>
<author><name sortKey="Pagoto, Sl" uniqKey="Pagoto S">SL Pagoto</name>
</author>
<author><name sortKey="Hurley, Tg" uniqKey="Hurley T">TG Hurley</name>
</author>
<author><name sortKey="Magner, Rp" uniqKey="Magner R">RP Magner</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Alberti, Kg" uniqKey="Alberti K">KG Alberti</name>
</author>
<author><name sortKey="Eckel, Rh" uniqKey="Eckel R">RH Eckel</name>
</author>
<author><name sortKey="Grundy, Sm" uniqKey="Grundy S">SM Grundy</name>
</author>
<author><name sortKey="Zimmet, Pz" uniqKey="Zimmet P">PZ Zimmet</name>
</author>
<author><name sortKey="Cleeman, Ji" uniqKey="Cleeman J">JI Cleeman</name>
</author>
</analytic>
</biblStruct>
</listBibl>
</div1>
</back>
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<pmc article-type="research-article"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">PLoS One</journal-id>
<journal-id journal-id-type="iso-abbrev">PLoS ONE</journal-id>
<journal-id journal-id-type="publisher-id">plos</journal-id>
<journal-id journal-id-type="pmc">plosone</journal-id>
<journal-title-group><journal-title>PLoS ONE</journal-title>
</journal-title-group>
<issn pub-type="epub">1932-6203</issn>
<publisher><publisher-name>Public Library of Science</publisher-name>
<publisher-loc>San Francisco, USA</publisher-loc>
</publisher>
</journal-meta>
<article-meta><article-id pub-id-type="pmid">24516542</article-id>
<article-id pub-id-type="pmc">3916323</article-id>
<article-id pub-id-type="publisher-id">PONE-D-13-26936</article-id>
<article-id pub-id-type="doi">10.1371/journal.pone.0087083</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject>
</subj-group>
<subj-group subj-group-type="Discipline-v2"><subject>Medicine</subject>
<subj-group><subject>Anatomy and Physiology</subject>
<subj-group><subject>Comparative Anatomy</subject>
</subj-group>
</subj-group>
<subj-group><subject>Clinical Research Design</subject>
<subj-group><subject>Cohort Studies</subject>
<subject>Epidemiology</subject>
<subject>Longitudinal Studies</subject>
</subj-group>
</subj-group>
<subj-group><subject>Epidemiology</subject>
<subj-group><subject>Lifecourse Epidemiology</subject>
</subj-group>
</subj-group>
<subj-group><subject>Nutrition</subject>
<subj-group><subject>Obesity</subject>
</subj-group>
</subj-group>
<subj-group><subject>Public Health</subject>
<subj-group><subject>Preventive Medicine</subject>
</subj-group>
</subj-group>
<subj-group><subject>Sports and Exercise Medicine</subject>
</subj-group>
</subj-group>
</article-categories>
<title-group><article-title>Dietary Quality and 6-Year Anthropometric Changes in a Sample of French Middle-Aged Overweight and Obese Adults</article-title>
<alt-title alt-title-type="running-head">Dietary Quality and Anthropometric Changes</alt-title>
</title-group>
<contrib-group><contrib contrib-type="author"><name><surname>Assmann</surname>
<given-names>Karen E.</given-names>
</name>
<xref ref-type="aff" rid="aff1"><sup>1</sup>
</xref>
<xref ref-type="corresp" rid="cor1"><sup>*</sup>
</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Lassale</surname>
<given-names>Camille</given-names>
</name>
<xref ref-type="aff" rid="aff1"><sup>1</sup>
</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Galan</surname>
<given-names>Pilar</given-names>
</name>
<xref ref-type="aff" rid="aff1"><sup>1</sup>
</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Hercberg</surname>
<given-names>Serge</given-names>
</name>
<xref ref-type="aff" rid="aff1"><sup>1</sup>
</xref>
<xref ref-type="aff" rid="aff2"><sup>2</sup>
</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Kesse-Guyot</surname>
<given-names>Emmanuelle</given-names>
</name>
<xref ref-type="aff" rid="aff1"><sup>1</sup>
</xref>
</contrib>
</contrib-group>
<aff id="aff1"><label>1</label>
<addr-line>Université Paris 13 Sorbonne Paris Cité, UREN (Nutritional Epidemiology Research Unit), Inserm (U557), Inra (U1125), Cnam, Bobigny, France</addr-line>
</aff>
<aff id="aff2"><label>2</label>
<addr-line>Département de Santé Publique, Hôpital Avicenne, Bobigny, France</addr-line>
</aff>
<contrib-group><contrib contrib-type="editor"><name><surname>Hribal</surname>
<given-names>Marta Letizia</given-names>
</name>
<role>Editor</role>
<xref ref-type="aff" rid="edit1"></xref>
</contrib>
</contrib-group>
<aff id="edit1"><addr-line>University of Catanzaro Magna Graecia, Italy</addr-line>
</aff>
<author-notes><corresp id="cor1">* E-mail: <email>k.assmann@uren.smbh.univ-paris13.fr</email>
</corresp>
<fn fn-type="conflict"><p><bold>Competing Interests: </bold>
The authors have declared that no competing interests exist.</p>
</fn>
<fn fn-type="con"><p>Analyzed the data: KEA. Wrote the paper: KEA. Made substantial contributions to the interpretation of the results and the revision of the manuscript: KEA CL PG SH EKG. Supervised the study: EKG. Conceived and designed the SU.VI.MAX study: SH PG.</p>
</fn>
</author-notes>
<pub-date pub-type="collection"><year>2014</year>
</pub-date>
<pub-date pub-type="epub"><day>6</day>
<month>2</month>
<year>2014</year>
</pub-date>
<volume>9</volume>
<issue>2</issue>
<elocation-id>e87083</elocation-id>
<history><date date-type="received"><day>29</day>
<month>6</month>
<year>2013</year>
</date>
<date date-type="accepted"><day>18</day>
<month>12</month>
<year>2013</year>
</date>
</history>
<permissions><copyright-year>2014</copyright-year>
<copyright-holder>Assmann et al</copyright-holder>
<license><license-p>This is an open-access article distributed under the terms of the <ext-link ext-link-type="uri" xlink:href="http://creativecommons.org/licenses/by/4.0/legalcode">Creative Commons Attribution License</ext-link>
, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.</license-p>
</license>
</permissions>
<abstract><sec><title>Background</title>
<p>Understanding the role of dietary quality in the progression of adiposity in populations already affected by overweight or obesity is crucial for the guidance of secondary prevention strategies.</p>
</sec>
<sec><title>Objective</title>
<p>To examine the association of diet quality, as reflected by the French Nutrition and Health Programme (Programme National Nutrition Santé, PNNS) – Guideline Score (GS), with 6-year-changes in weight and waist circumference.</p>
</sec>
<sec><title>Design and Methods</title>
<p>Subjects were 1029 male and 450 female participants of the SUplémentation en VItamines et Minéraux AntioXydants (SU.VI.MAX) cohort (1994–2002) with anthropometric variables at baseline and follow-up and available data for estimating diet quality at baseline. We employed analysis of variance and covariance models to investigate anthropometric changes (% of the initial value) by categories of the PNNS-GS, which contains both dietary components and a physical activity component, and of a modified score (mPNNS-GS) containing dietary components only.</p>
</sec>
<sec><title>Results</title>
<p>In men, a low (<6 points) PNNS-GS was associated with greater 6-year weight gain (adjusted mean: 3.63% [95% confidence interval: 2.87%; 4.39%]) as compared to a high (≥9 points) PNNS-GS (2.10% [1.39%; 2.81%]); p = 0.01. Results for the mPNNS-GS were very similar. In women, no associations between diet scores and weight change were observed. No significant relation between dietary quality and change in waist circumference was present among either men or women.</p>
</sec>
<sec><title>Conclusions</title>
<p>These results support a beneficial role of high dietary quality – as characterized by good adherence to official French nutritional guidelines – in secondary obesity prevention, among men.</p>
</sec>
</abstract>
<funding-group><funding-statement>Karen Assmann was supported by a scholarship of the German Academic Exchange Service (DAAD): a private, publicly funded, self-governing organization of higher education institutions in Germany. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.</funding-statement>
</funding-group>
<counts><page-count count="11"></page-count>
</counts>
</article-meta>
</front>
<body><sec id="s1"><title>Introduction</title>
<p>A rapidly growing part of the population worldwide is affected by overweight or obesity <xref rid="pone.0087083-Malik1" ref-type="bibr">[1]</xref>
, <xref rid="pone.0087083-Branca1" ref-type="bibr">[2]</xref>
. Primary and secondary obesity prevention (i.e. preventing an unfavourable progression of already existing overweight) are both crucial to prevent well-known comorbidities such as diabetes, cardiovascular disease and certain types of cancer <xref rid="pone.0087083-Malik1" ref-type="bibr">[1]</xref>
–<xref rid="pone.0087083-World2" ref-type="bibr">[4]</xref>
. The promotion of recommendations on diet and physical activity – two major modifiable factors related to body weight status – is a core element of public prevention strategies adopted by many countries <xref rid="pone.0087083-Painter1" ref-type="bibr">[5]</xref>
, <xref rid="pone.0087083-Bull1" ref-type="bibr">[6]</xref>
. In France, the National Nutrition and Health Program (Programme National Nutrition Santé, PNNS) was initiated in 2001 to elaborate official dietary and physical activity recommendations, to disseminate them to the general public, and finally to coordinate diverse measures aimed at facilitating adherence to these guidelines in everyday life <xref rid="pone.0087083-Hercberg1" ref-type="bibr">[7]</xref>
.</p>
<p>In epidemiological research, the development of indices to estimate dietary quality <xref rid="pone.0087083-Hu1" ref-type="bibr">[8]</xref>
has notably extended the possibilities to examine nutritional recommendations with respect to their potential impact on health determinants and disease outcomes. So-called “a priori methods” rely on the construction of scores reflecting adherence to recommendations or other dietary concepts, such as the Mediterranean diet <xref rid="pone.0087083-Waijers1" ref-type="bibr">[9]</xref>
, <xref rid="pone.0087083-Wirt1" ref-type="bibr">[10]</xref>
. Prospective studies investigating the relation between diet scores and anthropometric indicators tend to show that higher dietary quality is associated with favourable outcomes, despite some inconsistency <xref rid="pone.0087083-Beunza1" ref-type="bibr">[11]</xref>
–<xref rid="pone.0087083-Wolongevicz2" ref-type="bibr">[18]</xref>
. In particular, two studies have indicated a beneficial role of adherence to French recommendations on diet and physical activity concerning long-term changes in body weight and central adiposity <xref rid="pone.0087083-Lassale1" ref-type="bibr">[19]</xref>
, <xref rid="pone.0087083-KesseGuyot1" ref-type="bibr">[20]</xref>
.</p>
<p>So far, no prospective epidemiological study has specifically targeted a sample of overweight or obese subjects in order to gain further insight into the role of a priori- defined diet quality in secondary obesity prevention. Yet, a closer investigation of this population, especially at risk of experiencing health problems in the case of further weight gain, is highly warranted. Thus, the aim of this study was to examine the association of diet quality and physical activity levels, as reflected by a score measuring adherence to French recommendations (the PNNS – Guideline Score, PNNS-GS), with 6-year changes in weight and waist circumference (WC), in French overweight and obese adults.</p>
</sec>
<sec id="s2"><title>Methods and Procedures</title>
<sec id="s2a"><title>Study population</title>
<p>Subjects were overweight and obese participants of the Supplementation en VItamines et Minéraux AntioXydants (SU.VI.MAX) study, whose initial objective was to assess the effect of a daily supplementation with antioxidant vitamins and minerals at nutritional doses on the incidence of cardiovascular diseases, cancers and overall mortality, using a double-blind, placebo-controlled, randomized design with a follow-up of eight years (1994–2002). Details on this study have been reported elsewhere <xref rid="pone.0087083-Hercberg2" ref-type="bibr">[21]</xref>
. Briefly, after a national recruitment campaign with a call for volunteers living in France (women aged 35–60 years or men aged 45–60 years), 21 481 subjects were willing to participate and returned a completed baseline questionnaire and written informed consent. Of these, 13 017 met the study's eligibility criteria (lack of disease likely to hinder active participation or threatened 5-year survival; acceptance of the possibility to be given a placebo and acceptance of the constraints of participation; lack of previous regular supplementation with any of the vitamins or minerals in the supplement provided; absence of extreme beliefs or behaviour regarding diet) and were present at the inclusion visit. After exclusion of 6 subjects outside of the desired age range and of 270 subjects who had immediately withdrawn consent, 12 741 subjects (5028 men and 7713 women) were included in the final study sample.</p>
<p>The SU.VI.MAX study was approved by the Ethics Committee for Studies with Human Subjects at the Paris- Cochin Hospital (CCPPRB °706) and the ‘Commission Nationale de l'Informatique et des Libertés’ (CNIL °334641). Starting from inclusion, participants were invited to undergo either a biochemical or clinical examination on a yearly basis.</p>
</sec>
<sec id="s2b"><title>Dietary assessment</title>
<p>One 24-h dietary record was requested every 2 months, starting from baseline (1994). If the participants wished so, they also had the possibility to enter food records more frequently. The 24-h records consisted of self-reporting any food and beverage consumption occurring over a 24-h period, using the Minitel Telematic Network, small terminals (similar to personal computers) widely used in France at the beginning of the 1990s. In the case of incoherent reported caloric intake, dietitians inquired complementary information via telephone. Moreover, dietitians gave assistance to volunteers via telephone when they encountered problems with data entry. The days of the 24-h records were determined in advance so that weekly and seasonal variation could be taken into account. To facilitate the evaluation of food portion sizes, participants were provided with an instruction manual that included validated photographs of more than 250 typical French foods shown in three different portion sizes <xref rid="pone.0087083-LeMoullec1" ref-type="bibr">[22]</xref>
. Intermediate portion sizes could also be chosen, leading to a total of seven possible portion sizes. Nutrient intakes were calculated using the SU.VI.MAX food composition table, which included more than 900 different foods <xref rid="pone.0087083-Hercberg3" ref-type="bibr">[23]</xref>
.</p>
<p>For this prospective analysis, we averaged – for each subject – data on nutrient and food group consumption from all eligible 24-h records during the first 26 months of the study (1994–1996) as a measure for baseline diet. While single 24-h records may not accurately reflect usual dietary behaviour, averaged nutritional intakes from repeated 24-h records can be regarded as a proxy for habitual dietary intakes <xref rid="pone.0087083-Mennen1" ref-type="bibr">[24]</xref>
. Information on the consumption of alcohol and seafood was not obtained by 24-h records but by questionnaires, as certain particularities have to be considered (amongst other things, these food groups tend to be consumed less frequently than others). Alcohol intake (grams of ethanol per day) was estimated using a short, validated, semi-quantitative dietary questionnaire. In the validation study, there was a high concordance between the self-administered questionnaire and a dietetic interview using the dietary history method (correlation coefficients for alcohol: r = 0.80 in men and r = 0.75 in women) <xref rid="pone.0087083-Lasfargues1" ref-type="bibr">[25]</xref>
. Specific information on weekly consumption of seafood was collected by a self-administrated questionnaire at baseline.</p>
</sec>
<sec id="s2c"><title>Physical activity</title>
<p>Physical activity was assessed in 1998, using a French validated, self-administered version of the Modifiable Activity Questionnaire (MAQ). In the French validation study, a high level of concordance was shown for self-administration vs. interview (r = 0.90 for the leisure activity subscore that we considered in our analyses) <xref rid="pone.0087083-Vuillemin1" ref-type="bibr">[26]</xref>
. In validation studies of the original questionnaire, the leisure activity subscore had a correlation of r = 0.56 with total energy expenditure (measured by double-labelled water) divided by basic metabolic rate <xref rid="pone.0087083-Schulz1" ref-type="bibr">[27]</xref>
; and of r = 0.62 with counts from an electronic single-plane accelerometer <xref rid="pone.0087083-Kriska1" ref-type="bibr">[28]</xref>
.</p>
<p>In the SU.VI.MAX study, type, frequency, and duration of leisure time activities performed at least 10 times during the past 12 months (with a minimal duration of 10 minutes per session) were collected. Using published compendiums <xref rid="pone.0087083-Ainsworth1" ref-type="bibr">[29]</xref>
, <xref rid="pone.0087083-Ainsworth2" ref-type="bibr">[30]</xref>
, we assigned metabolic equivalent task-hours to each activity reported and computed average metabolic equivalent task-hours per week of physical activity.</p>
</sec>
<sec id="s2d"><title>Anthropometric data</title>
<p>Anthropometric measurements were performed by trained technicians, at the first (1995–1996) and last (2001–2002) clinical examinations during follow-up. Weight was measured with an electronic scale (Seca, Hamburg, Germany), with subjects wearing indoor clothing and no shoes. Height was measured under the same conditions with a wall-mounted stadiometer. Waist circumference was measured as the circumference midway between the lower ribs and iliac crests, in a standing position and with an inelastic tape.</p>
</sec>
<sec id="s2e"><title>Covariates</title>
<p>Data on gender, date of birth, tobacco use status and educational level were collected at study inclusion, using a self-administrated questionnaire. Information on menopausal status was obtained by questionnaires.</p>
</sec>
<sec id="s2f"><title>Selection of participants for the present analyses</title>
<p><xref ref-type="fig" rid="pone-0087083-g001"><bold>Figure 1</bold>
</xref>
shows the selection of participants for the present analyses. We chose to only include subjects aged 45–60 years at baseline in order to obtain a more homogenous sample; n = 9751 subjects of the original SU.VI.MAX study sample met this criterion. Measured body mass index (BMI) at baseline was available for 7104 of these subjects, and n = 2990 individuals were overweight or obese (measured BMI ≥25) at baseline. Of these, we included all subjects with at least three 24-h dietary records provided during the first two years of follow-up (1994–1996), who had no missing dietary, anthropometric or covariate data. Subjects with incident cases of cancer or ischemic disease during the first two years of follow-up were excluded as such incidents are likely to provoke changes in dietary habits and weight status. This resulted in a final study sample of 1479 participants (1029 men and 450 women).</p>
<fig id="pone-0087083-g001" orientation="portrait" position="float"><object-id pub-id-type="doi">10.1371/journal.pone.0087083.g001</object-id>
<label>Figure 1</label>
<caption><title>Selection of participants of the SU.VI.MAX study, France, 1994–2002, for the present analyses.</title>
</caption>
<graphic xlink:href="pone.0087083.g001"></graphic>
</fig>
<p>As is the general rule in the SU.VI.MAX cohort <xref rid="pone.0087083-Lairon1" ref-type="bibr">[31]</xref>
, dietary records that reported <100 or >6000 kcal per day were considered implausible and were thus excluded from analyses. Further, men reporting <800 kcal per day and women reporting <500 kcal per day across more than one third of their dietary records were also excluded. In the final study sample, there were, on average, 10 dietary records available for each participant (median and mode of the number of dietary records: 11 and 13, respectively; range: 3–20). The proportion of participants with only 3 records or with more than 14 records was very low (4.4% and 1.1%, respectively).</p>
</sec>
<sec id="s2g"><title>Data computation and statistical analysis</title>
<sec id="s2g1"><title>PNNS-GS computation</title>
<p>PNNS-GS computation, including food grouping, serving sizes, scoring, cut-off values and penalties, has previously been described in detail <xref rid="pone.0087083-Estaquio1" ref-type="bibr">[32]</xref>
. Briefly, the score includes 13 components and has a range of 0–15 points. Eight components refer to French food serving recommendations, four concern nutrients and food groups whose consumption is to be limited, and one component covers adherence to physical activity recommendations.</p>
<p>Scoring and cutoff values are presented in <xref ref-type="table" rid="pone-0087083-t001"><bold>Table 1</bold>
</xref>
. A penalty for overconsumption was assigned to individuals whose energy intakes were higher than estimated energy needs <xref rid="pone.0087083-Estaquio1" ref-type="bibr">[32]</xref>
.</p>
<table-wrap id="pone-0087083-t001" orientation="portrait" position="float"><object-id pub-id-type="doi">10.1371/journal.pone.0087083.t001</object-id>
<label>Table 1</label>
<caption><title>Construction of the Programme National Nutrition Santé – Guideline Score (PNNS-GS).</title>
</caption>
<alternatives><graphic id="pone-0087083-t001-1" xlink:href="pone.0087083.t001"></graphic>
<table frame="hsides" rules="groups"><colgroup span="1"><col align="left" span="1"></col>
<col align="center" span="1"></col>
<col align="center" span="1"></col>
<col align="center" span="1"></col>
<col align="center" span="1"></col>
</colgroup>
<thead><tr><td colspan="2" align="left" rowspan="1"></td>
<td align="left" rowspan="1" colspan="1">Recommendation<xref ref-type="table-fn" rid="nt101">1</xref>
</td>
<td align="left" rowspan="1" colspan="1">Scoring criteria<xref ref-type="table-fn" rid="nt102">2</xref>
</td>
<td align="left" rowspan="1" colspan="1">Score</td>
</tr>
</thead>
<tbody><tr><td align="left" rowspan="1" colspan="1"><bold>1. Fruits and vegetables</bold>
</td>
<td colspan="2" align="left" rowspan="1">At least 5/d</td>
<td align="left" rowspan="1" colspan="1">[0–3.5]</td>
<td align="left" rowspan="1" colspan="1">0</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"></td>
<td colspan="2" align="left" rowspan="1"></td>
<td align="left" rowspan="1" colspan="1">[3.5–5]</td>
<td align="left" rowspan="1" colspan="1">0.5</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"></td>
<td colspan="2" align="left" rowspan="1"></td>
<td align="left" rowspan="1" colspan="1">[5–7.5]</td>
<td align="left" rowspan="1" colspan="1">1</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"></td>
<td colspan="2" align="left" rowspan="1"></td>
<td align="left" rowspan="1" colspan="1">≥7.5</td>
<td align="left" rowspan="1" colspan="1">2</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"><bold>2. Bread, cereals, potatoes</bold>
</td>
<td colspan="2" align="left" rowspan="1">At each meal according to</td>
<td align="left" rowspan="1" colspan="1">[0–1]</td>
<td align="left" rowspan="1" colspan="1">0</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"><bold>and legumes</bold>
</td>
<td colspan="2" align="left" rowspan="1">appetite</td>
<td align="left" rowspan="1" colspan="1"><xref rid="pone.0087083-Malik1" ref-type="bibr">[1]</xref>
–<xref rid="pone.0087083-World1" ref-type="bibr">[3]</xref>
</td>
<td align="left" rowspan="1" colspan="1">0.5</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"></td>
<td colspan="2" align="left" rowspan="1"></td>
<td align="left" rowspan="1" colspan="1"><xref rid="pone.0087083-World1" ref-type="bibr">[3]</xref>
–<xref rid="pone.0087083-Bull1" ref-type="bibr">[6]</xref>
</td>
<td align="left" rowspan="1" colspan="1">1</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"></td>
<td colspan="2" align="left" rowspan="1"></td>
<td align="left" rowspan="1" colspan="1">≥6</td>
<td align="left" rowspan="1" colspan="1">0.5</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"><bold>3. Whole grain food</bold>
</td>
<td colspan="2" align="left" rowspan="1">Choose whole grains and</td>
<td align="left" rowspan="1" colspan="1">[0–1/3]</td>
<td align="left" rowspan="1" colspan="1">0</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"></td>
<td colspan="2" align="left" rowspan="1">whole-grain breads more</td>
<td align="left" rowspan="1" colspan="1">[1/3–2/3]</td>
<td align="left" rowspan="1" colspan="1">0.5</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"></td>
<td colspan="2" align="left" rowspan="1">often</td>
<td align="left" rowspan="1" colspan="1">≥2/3</td>
<td align="left" rowspan="1" colspan="1">1</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"><bold>4. Milk and dairy</bold>
</td>
<td colspan="2" align="left" rowspan="1">3/d (≥55-years-old: 3 to</td>
<td align="left" rowspan="1" colspan="1">[0–1]</td>
<td align="left" rowspan="1" colspan="1">0</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"><bold>products</bold>
</td>
<td colspan="2" align="left" rowspan="1">4/d)</td>
<td align="left" rowspan="1" colspan="1">[1–2.5]</td>
<td align="left" rowspan="1" colspan="1">0.5</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"></td>
<td colspan="2" align="left" rowspan="1"></td>
<td align="left" rowspan="1" colspan="1">[2.5–3.5] (55-years-old: [2.5–4.5])</td>
<td align="left" rowspan="1" colspan="1">1</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"></td>
<td colspan="2" align="left" rowspan="1"></td>
<td align="left" rowspan="1" colspan="1">>3.5 (55-years-old: >4.5)</td>
<td align="left" rowspan="1" colspan="1">0</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"><bold>5. Meat, poultry seafood</bold>
</td>
<td colspan="2" align="left" rowspan="1">1 to 2/d</td>
<td align="left" rowspan="1" colspan="1">0</td>
<td align="left" rowspan="1" colspan="1">0</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"><bold>and eggs</bold>
</td>
<td colspan="2" align="left" rowspan="1"></td>
<td align="left" rowspan="1" colspan="1">[0–1]</td>
<td align="left" rowspan="1" colspan="1">0.5</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"></td>
<td colspan="2" align="left" rowspan="1"></td>
<td align="left" rowspan="1" colspan="1"><xref rid="pone.0087083-Malik1" ref-type="bibr">[1]</xref>
–<xref rid="pone.0087083-Branca1" ref-type="bibr">[2]</xref>
</td>
<td align="left" rowspan="1" colspan="1">1</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"></td>
<td colspan="2" align="left" rowspan="1"></td>
<td align="left" rowspan="1" colspan="1">>2</td>
<td align="left" rowspan="1" colspan="1">0.5</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"><bold>6. Seafood</bold>
</td>
<td colspan="2" align="left" rowspan="1">At least 2/week</td>
<td align="left" rowspan="1" colspan="1"><2/week</td>
<td align="left" rowspan="1" colspan="1">0</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"></td>
<td colspan="2" align="left" rowspan="1"></td>
<td align="left" rowspan="1" colspan="1">≥2/week</td>
<td align="left" rowspan="1" colspan="1">1</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"><bold>7. Added fat</bold>
</td>
<td colspan="2" align="left" rowspan="1">Limit consumption</td>
<td align="left" rowspan="1" colspan="1">Lipids from added fat >16% EI<xref ref-type="table-fn" rid="nt103">3</xref>
/d</td>
<td align="left" rowspan="1" colspan="1">0</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"></td>
<td colspan="2" align="left" rowspan="1"></td>
<td align="left" rowspan="1" colspan="1">Lipids from added fat ≤16% EI/d</td>
<td align="left" rowspan="1" colspan="1">1</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"><bold>8. Vegetable added fat</bold>
</td>
<td colspan="2" align="left" rowspan="1">Favour fat of vegetable origin</td>
<td align="left" rowspan="1" colspan="1">No use of vegetable oil or ratio vegetable oil/total added fats≤0.5</td>
<td align="left" rowspan="1" colspan="1">0</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"></td>
<td colspan="2" align="left" rowspan="1"></td>
<td align="left" rowspan="1" colspan="1">No use of added fats or ratio vegetable oil/total added fats >0.5</td>
<td align="left" rowspan="1" colspan="1">1</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"><bold>9. Sweetened foods</bold>
</td>
<td colspan="2" align="left" rowspan="1">Limit consumption</td>
<td align="left" rowspan="1" colspan="1">Added sugar from sweetened foods ≥17.5% EI/d</td>
<td align="left" rowspan="1" colspan="1">−0.5</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"></td>
<td colspan="2" align="left" rowspan="1"></td>
<td align="left" rowspan="1" colspan="1">Added sugar from sweetened foods 17.5–12.5% EI/d</td>
<td align="left" rowspan="1" colspan="1">0</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"></td>
<td colspan="2" align="left" rowspan="1"></td>
<td align="left" rowspan="1" colspan="1">Added sugar from sweetened foods <12.5% EI/d</td>
<td align="left" rowspan="1" colspan="1">1</td>
</tr>
<tr><td colspan="2" align="left" rowspan="1"><bold>Beverages</bold>
</td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"></td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"><bold>10. non-alcoholic</bold>
</td>
<td colspan="2" align="left" rowspan="1">Drink water as desired</td>
<td align="left" rowspan="1" colspan="1"><1l water and >250 ml soda/d</td>
<td align="left" rowspan="1" colspan="1">0</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"></td>
<td colspan="2" align="left" rowspan="1">Limit sweetened</td>
<td align="left" rowspan="1" colspan="1">≥1l water and >250 ml soda/d</td>
<td align="left" rowspan="1" colspan="1">0.5</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"></td>
<td colspan="2" align="left" rowspan="1">beverages: no more than 1</td>
<td align="left" rowspan="1" colspan="1"><1l water and ≤250 ml soda/d</td>
<td align="left" rowspan="1" colspan="1">0.75</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"></td>
<td colspan="2" align="left" rowspan="1">glass/d</td>
<td align="left" rowspan="1" colspan="1">≥1l water and ≤250 ml soda/d</td>
<td align="left" rowspan="1" colspan="1">1</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"><bold>11. alcoholic</bold>
</td>
<td colspan="2" align="left" rowspan="1">Women advised to drink</td>
<td align="left" rowspan="1" colspan="1">Ethanol >20 g/d for women and >30g/d for men</td>
<td align="left" rowspan="1" colspan="1">0</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"></td>
<td colspan="2" align="left" rowspan="1">≤2 glasses of wine/d and</td>
<td align="left" rowspan="1" colspan="1">Ethanol ≤20 g/d for women and ≤30g/d for men</td>
<td align="left" rowspan="1" colspan="1">0.8</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"></td>
<td colspan="2" align="left" rowspan="1">≤3 glasses/d for men</td>
<td align="left" rowspan="1" colspan="1">Abstainers and irregular consumers (</td>
<td align="left" rowspan="1" colspan="1">1</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"><bold>12. Salt</bold>
<xref ref-type="table-fn" rid="nt104">4</xref>
</td>
<td colspan="2" align="left" rowspan="1">Limit consumption</td>
<td align="left" rowspan="1" colspan="1">>12g/d</td>
<td align="left" rowspan="1" colspan="1">−0.5</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"></td>
<td colspan="2" align="left" rowspan="1"></td>
<td align="left" rowspan="1" colspan="1"><xref rid="pone.0087083-Wirt1" ref-type="bibr">[10]</xref>
–<xref rid="pone.0087083-Gao1" ref-type="bibr">[12]</xref>
g/d</td>
<td align="left" rowspan="1" colspan="1">0</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"></td>
<td colspan="2" align="left" rowspan="1"></td>
<td align="left" rowspan="1" colspan="1"><xref rid="pone.0087083-Hu1" ref-type="bibr">[8]</xref>
–<xref rid="pone.0087083-Wirt1" ref-type="bibr">[10]</xref>
g/d</td>
<td align="left" rowspan="1" colspan="1">0.5</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"></td>
<td colspan="2" align="left" rowspan="1"></td>
<td align="left" rowspan="1" colspan="1"><xref rid="pone.0087083-Bull1" ref-type="bibr">[6]</xref>
–<xref rid="pone.0087083-Hu1" ref-type="bibr">[8]</xref>
g/d</td>
<td align="left" rowspan="1" colspan="1">1</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"></td>
<td colspan="2" align="left" rowspan="1"></td>
<td align="left" rowspan="1" colspan="1">≤6 g/d</td>
<td align="left" rowspan="1" colspan="1">1.5</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"><bold>13.Physical activity</bold>
</td>
<td colspan="2" align="left" rowspan="1">At least the equivalent of</td>
<td align="left" rowspan="1" colspan="1">[0–30] min/d</td>
<td align="left" rowspan="1" colspan="1">0</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"></td>
<td colspan="2" align="left" rowspan="1">30 min/d of brisk walking</td>
<td align="left" rowspan="1" colspan="1">[30–60] min/d</td>
<td align="left" rowspan="1" colspan="1">1</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"></td>
<td colspan="2" align="left" rowspan="1"></td>
<td align="left" rowspan="1" colspan="1">≥60 min/d</td>
<td align="left" rowspan="1" colspan="1">1.5</td>
</tr>
</tbody>
</table>
</alternatives>
<table-wrap-foot><fn id="nt101"><label>1</label>
<p>Recommendations of the Programme National Nutrition Santé.</p>
</fn>
<fn id="nt102"><label>2</label>
<p>Servings per day unless otherwise indicated.</p>
</fn>
<fn id="nt103"><label>3</label>
<p>EI: energy intake without alcohol.</p>
</fn>
<fn id="nt104"><label>4</label>
<p>Established according to French recommended dietary allowances.</p>
</fn>
</table-wrap-foot>
</table-wrap>
<p>Energy needs were estimated on the basis of basal metabolic rate (calculated according to Schofield <xref rid="pone.0087083-Schofield1" ref-type="bibr">[33]</xref>
) and physical activity levels. If energy intake exceeded estimated energy needs by more than 5%, an identical fraction was deducted from the PNNS-GS. For example, an energy over-consumption of 10% would result in reducing a PNNS-GS of 7 points to 6.3 points. The rationale for this approach is to account for the fact that subjects with high energy consumption will more easily meet recommendations on food groups for which consuming a certain minimal amount or more is considered as ‘healthy’ <xref rid="pone.0087083-Waijers1" ref-type="bibr">[9]</xref>
. High scores on the PNNS-GS should not reflect a high general food intake, but a balanced diet with adequate caloric intake. In order to give the reader the possibility to assess the impact of penalization on our results, we present analyses with an unpenalized PNNS-GS in a supplemental table (<bold><xref ref-type="supplementary-material" rid="pone.0087083.s001">Table S1</xref>
</bold>
).</p>
<p>Compliance with physical activity recommendations was determined through the MAQ when available, considering that half an hour of moderate activity on five days a week was equivalent to 16.25 metabolic equivalent task-hours per week. When the MAQ information was missing (this was the case for 14% of participants), data were obtained from two items of another baseline questionnaire. The respective items inquired whether the subject had a regular physical activity – and if yes, whether they estimated this activity to be equivalent to ≥ one hour of walking per day). Subjects who stated having no regular physical activity were classed into the low physical activity group (<30 min/day of equivalent walking) and those who indicated having a regular physical activity – and more specifically one equivalent to walking ≥ one hour per day – were classed into the high physical activity group. Regression imputation was applied to class the remaining subjects into the low or medium physical activity groups.</p>
</sec>
<sec id="s2g2"><title>Statistical analysis</title>
<p>Changes in weight and WC were computed as the difference between follow-up (2001–2002) and baseline (1995–1996) values, and stated as a percentage of the baseline value. In order to give information about the SU.VI.MAX participants who were not included in our analyses, we compared included and excluded participants at two stages of the selection process (shown in <xref ref-type="fig" rid="pone-0087083-g001"><bold>Figure 1</bold>
</xref>
), using the Kruskal-Wallis test and the Chi<sup>2</sup>
test. Firstly, we compared participants excluded due to missing measured baseline BMI (n = 2647) with participants not excluded at this stage (n = 7104). Secondly, we compared participants who were in the desired age range and overweight or obese at baseline, but excluded due to missing data and other criteria (n = 1511), with the participants finally included into our analysis (n = 1479).</p>
<p>Baseline characteristics of participants included in the analyses were presented according to categories of the PNNS-GS, and differences across categories were tested using the Kruskal-Wallis test and the Chi<sup>2</sup>
test. An exploration of the distribution of our main study outcome (6-year-weight-change) across quartiles and quintiles of the PNNS-GS indicated a non-linear relationship between the two variables. Accordingly, we decided to categorize the PNNS-GS and mPNNS-GS and to use analysis of variance and covariance (ANCOVA) models for our main analyses, providing adjusted means (least squares means) of our outcome variables by diet score categories. To account for multiple comparisons, the significance levels presented were corrected according to Dunnett <xref rid="pone.0087083-Dunnett1" ref-type="bibr">[34]</xref>
.</p>
<p>The choice of appropriate diet score cut-offs was based on the following elements: Cut-offs should 1) represent a sufficiently broad range in PNNS-GS; 2) lead to groups with a sufficient number of participants; 3) fit the context in which the PNNS-GS was originally created and validated (mean ± standard deviation of the score in the validation sample <xref rid="pone.0087083-Estaquio1" ref-type="bibr">[32]</xref>
: 7.54±1.91 in men; 7.87±1.86 in women). Finally, the following cut-offs were chosen: <6 points (low); ≥6 and <9 points (medium); ≥9 points (high); with the low and high cut-offs approximately corresponding to the mean PNNS-GS within the original validation sample ± its standard deviation (SD): 7.5±1.5 points. Cut-offs for the mPNNS-GS were defined as <5.5 points; 5.5 to <8.5 points; and ≥8.5 points.</p>
<p>Because there was a significant interaction between the categorized PNNS-GS and gender (p = 0.01), all analyses were stratified by gender. We created three ANCOVA models: a crude model (A), a model adjusted for age and energy intake (B) and a fully-adjusted model (C), further adjusted for supplementation group, number of dietary records, initial height, education level, smoking, and (in women) menopausal status. For analyses concerning the mPNNS-GS, models B and C were also adjusted for physical activity. Concerning women, model C is presented for illustrative purposes only and has to be interpreted with caution given the high number of adjustment variables in relation to the small number of women in the “low score” group. Identical adjustments were used when modeling weight change and change in WC.</p>
<p>All statistical analyses were performed using SAS software (Release 9.1, SAS Institute Inc., Cary, NC, USA). All tests performed were two-sided and p<0.05 was considered significant.</p>
</sec>
</sec>
</sec>
<sec sec-type="results" id="s3"><title>Results</title>
<sec id="s3a"><title>Comparison of included and excluded participants</title>
<p>The proportions of males and of non-smokers among subjects excluded due to missing measured baseline BMI (n = 2647) were slightly smaller as compared to subjects with baseline anthropometric data (n = 7104): 48.2% vs. 51.2% (p = 0.008) and 44.6% vs. 48.2% (p<.0001), respectively (data not shown). There were no significant differences concerning education level, baseline age and self-declared baseline BMI.</p>
<p><xref ref-type="table" rid="pone-0087083-t002"><bold>Table 2</bold>
</xref>
presents baseline characteristics of SU.VI.MAX participants included in our analyses (n = 1479), as compared to participants who were aged 45–60 years and overweight or obese at baseline, but excluded due to missing data and other criteria. The population of excluded participants had a slightly higher median (declared) baseline BMI and a lower proportion of males. Moreover, they were less frequent to have only primary education – but also less frequent to have university level (or equivalent) education. Concerning baseline age and tobacco use status, the two populations were comparable.</p>
<table-wrap id="pone-0087083-t002" orientation="portrait" position="float"><object-id pub-id-type="doi">10.1371/journal.pone.0087083.t002</object-id>
<label>Table 2</label>
<caption><title>Characteristics of participants included in the analyses (n = 1479), as compared to excluded participants (n = 1511)<xref ref-type="table-fn" rid="nt108">1</xref>
.</title>
</caption>
<alternatives><graphic id="pone-0087083-t002-2" xlink:href="pone.0087083.t002"></graphic>
<table frame="hsides" rules="groups"><colgroup span="1"><col align="left" span="1"></col>
<col align="center" span="1"></col>
<col align="center" span="1"></col>
<col align="center" span="1"></col>
<col align="center" span="1"></col>
<col align="center" span="1"></col>
</colgroup>
<thead><tr><td align="left" rowspan="1" colspan="1"></td>
<td colspan="2" align="left" rowspan="1">Included participants (n = 1479)</td>
<td colspan="2" align="left" rowspan="1">Excluded participants (n = 1511)</td>
<td align="left" rowspan="1" colspan="1"></td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"><italic>n</italic>
<xref ref-type="table-fn" rid="nt110">2</xref>
</td>
<td align="left" rowspan="1" colspan="1">Median (Q1, Q3) or n (%)<xref ref-type="table-fn" rid="nt111">3</xref>
</td>
<td align="left" rowspan="1" colspan="1"><italic>n</italic>
<xref ref-type="table-fn" rid="nt110">2</xref>
</td>
<td align="left" rowspan="1" colspan="1">Median (Q1, Q3) or n (%)</td>
<td align="left" rowspan="1" colspan="1">P<xref ref-type="table-fn" rid="nt112">4</xref>
</td>
</tr>
</thead>
<tbody><tr><td align="left" rowspan="1" colspan="1"><bold>Baseline age (years)</bold>
</td>
<td align="left" rowspan="1" colspan="1"><italic>1479</italic>
</td>
<td align="left" rowspan="1" colspan="1">51.5 (48.2; 56.0)</td>
<td align="left" rowspan="1" colspan="1"><italic>1511</italic>
</td>
<td align="left" rowspan="1" colspan="1">51.3 (48.0; 55.7)</td>
<td align="left" rowspan="1" colspan="1">0.5</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"><bold>Declared baseline BMI (kg/m<sup>2</sup>
)</bold>
</td>
<td align="left" rowspan="1" colspan="1"><italic>1451</italic>
</td>
<td align="left" rowspan="1" colspan="1">26.4 (25.2; 28.0)</td>
<td align="left" rowspan="1" colspan="1"><italic>1431</italic>
</td>
<td align="left" rowspan="1" colspan="1">26.7 (25.3; 28.7)</td>
<td align="left" rowspan="1" colspan="1">0.0002</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"><bold>Male sex (%)</bold>
</td>
<td align="left" rowspan="1" colspan="1"><italic>1479</italic>
</td>
<td align="left" rowspan="1" colspan="1">1029 (69.6)</td>
<td align="left" rowspan="1" colspan="1"><italic>1511</italic>
</td>
<td align="left" rowspan="1" colspan="1">921 (61.0)</td>
<td align="left" rowspan="1" colspan="1"><.0001</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"><bold>Education level (%)</bold>
</td>
<td align="left" rowspan="1" colspan="1"><italic>1479</italic>
</td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"><italic>1473</italic>
</td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1">0.04</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1">Primary education</td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1">407 (27.5)</td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1">374 (25.4)</td>
<td align="left" rowspan="1" colspan="1"></td>
</tr>
<tr><td align="left" rowspan="1" colspan="1">High school diploma</td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1">548 (37.1)</td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1">614 (41.7)</td>
<td align="left" rowspan="1" colspan="1"></td>
</tr>
<tr><td align="left" rowspan="1" colspan="1">University level or equivalent</td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1">524 (35.4)</td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1">485 (32.9)</td>
<td align="left" rowspan="1" colspan="1"></td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"><bold>Tobacco use status (%)</bold>
</td>
<td align="left" rowspan="1" colspan="1"><italic>1479</italic>
</td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"><italic>1389</italic>
</td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1">0.1</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1">Non-smoker</td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1">613 (41.4)</td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1">572 (41.2)</td>
<td align="left" rowspan="1" colspan="1"></td>
</tr>
<tr><td align="left" rowspan="1" colspan="1">Former smoker</td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1">705 (47.7)</td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1">626 (45.1)</td>
<td align="left" rowspan="1" colspan="1"></td>
</tr>
<tr><td align="left" rowspan="1" colspan="1">Smoker</td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1">161 (10.9)</td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1">191 (13.8)</td>
<td align="left" rowspan="1" colspan="1"></td>
</tr>
</tbody>
</table>
</alternatives>
<table-wrap-foot><fn id="nt105"><label></label>
<p>SU.VI.MAX Study, France, 1994–1996.</p>
</fn>
<fn id="nt106"><label></label>
<p>BMI: body mass index.</p>
</fn>
<fn id="nt107"><label></label>
<p>Q: quartile.</p>
</fn>
<fn id="nt108"><label>1</label>
<p>Parent population: participants of the SU.VI.MAX study with a baseline age of 45–60 years and a baseline body.</p>
</fn>
<fn id="nt109"><label></label>
<p>mass index of ≥25 kg/m<sup>2</sup>
(n = 2990).</p>
</fn>
<fn id="nt110"><label>2</label>
<p>Number of participants for which data were available.</p>
</fn>
<fn id="nt111"><label>3</label>
<p>Median (Q1, Q3) for continuous variables and n (%) for categorical variables.</p>
</fn>
<fn id="nt112"><label>4</label>
<p>Kruskal-Wallis-test for continuous variables and Chi<sup>2</sup>
-test for categorical variables.</p>
</fn>
</table-wrap-foot>
</table-wrap>
</sec>
<sec id="s3b"><title>Subject characteristics</title>
<p>Of 12,741 adults initially included in the SU.VI.MAX cohort, 1497 overweight and obese subjects (1029 men, 450 women) with a mean baseline age of 52.1 (SD: 4.6) and a mean baseline BMI of 27.8 (SD: 2.8) were finally included in the present analyses (<xref ref-type="fig" rid="pone-0087083-g001"><bold>Figure 1</bold>
</xref>
). The prevalence of obesity (BMI ≥30 kg/m<sup>2</sup>
) in our sample was 17.1% at baseline (13.7% in men and 24.9% in women). About half of the women in our sample (51.8%) were post-menopausal at baseline.</p>
<p>In <xref ref-type="table" rid="pone-0087083-t003"><bold>Table 3</bold>
</xref>
, we present baseline characteristics of participants according to gender and by categories of the PNNS-GS. Men and women in the highest category had the lowest energy intake, were oldest, least likely to report a low physical activity level and had the smallest baseline waist circumference. Moreover, women with the highest diet quality also had the smallest baseline BMI and were the least likely to be obese or abdominally obese. Non-smokers were more frequent in the highest PNNS-GS category only among men.</p>
<table-wrap id="pone-0087083-t003" orientation="portrait" position="float"><object-id pub-id-type="doi">10.1371/journal.pone.0087083.t003</object-id>
<label>Table 3</label>
<caption><title>Baseline characteristics of participants included into the analyses<xref ref-type="table-fn" rid="nt116">1</xref>
.</title>
</caption>
<alternatives><graphic id="pone-0087083-t003-3" xlink:href="pone.0087083.t003"></graphic>
<table frame="hsides" rules="groups"><colgroup span="1"><col align="left" span="1"></col>
<col align="center" span="1"></col>
<col align="center" span="1"></col>
<col align="center" span="1"></col>
<col align="center" span="1"></col>
<col align="center" span="1"></col>
<col align="center" span="1"></col>
<col align="center" span="1"></col>
<col align="center" span="1"></col>
</colgroup>
<thead><tr><td align="left" rowspan="1" colspan="1"></td>
<td colspan="4" align="left" rowspan="1">Men (n = 1029)</td>
<td colspan="4" align="left" rowspan="1">Women (n = 450)</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1">Low PNNS-GS</td>
<td align="left" rowspan="1" colspan="1">Medium PNNS-GS</td>
<td align="left" rowspan="1" colspan="1">High PNNS-GS</td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1">Low PNNS-GS</td>
<td align="left" rowspan="1" colspan="1">Medium PNNS-GS</td>
<td align="left" rowspan="1" colspan="1">High PNNS-GS</td>
<td align="left" rowspan="1" colspan="1"></td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1">(n = 195)</td>
<td align="left" rowspan="1" colspan="1">(n = 593)</td>
<td align="left" rowspan="1" colspan="1">(n = 241)</td>
<td align="left" rowspan="1" colspan="1">P<xref ref-type="table-fn" rid="nt117">2</xref>
</td>
<td align="left" rowspan="1" colspan="1">(n = 40)</td>
<td align="left" rowspan="1" colspan="1">(n = 255)</td>
<td align="left" rowspan="1" colspan="1">(n = 155)</td>
<td align="left" rowspan="1" colspan="1">P<xref ref-type="table-fn" rid="nt117">2</xref>
</td>
</tr>
</thead>
<tbody><tr><td align="left" rowspan="1" colspan="1"><bold>Diet</bold>
</td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"></td>
</tr>
<tr><td align="left" rowspan="1" colspan="1">Daily energy consumption (kcal)</td>
<td align="left" rowspan="1" colspan="1">2795 (2414; 3150)</td>
<td align="left" rowspan="1" colspan="1">2443 (2095; 2797)</td>
<td align="left" rowspan="1" colspan="1">2242 (1947; 2557)</td>
<td align="left" rowspan="1" colspan="1"><.0001</td>
<td align="left" rowspan="1" colspan="1">2198 (1685; 2554)</td>
<td align="left" rowspan="1" colspan="1">1724 (1416; 2088)</td>
<td align="left" rowspan="1" colspan="1">1667 (1376; 1924)</td>
<td align="left" rowspan="1" colspan="1"><.0001</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1">PNNS-GS (0–15 points)</td>
<td align="left" rowspan="1" colspan="1">5.05 (4.25; 5.47)</td>
<td align="left" rowspan="1" colspan="1">7.42 (6.75; 8.25)</td>
<td align="left" rowspan="1" colspan="1">9.80 (9.30; 10.50)</td>
<td align="left" rowspan="1" colspan="1"><.0001</td>
<td align="left" rowspan="1" colspan="1">5.18 (4.41; 5.75)</td>
<td align="left" rowspan="1" colspan="1">7.75 (7.00; 8.25)</td>
<td align="left" rowspan="1" colspan="1">9.80 (9.30; 10.50)</td>
<td align="left" rowspan="1" colspan="1"><.0001</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1">mPNNGS-GS (0–13.5 points)</td>
<td align="left" rowspan="1" colspan="1">4.75 (4.05; 5.30)</td>
<td align="left" rowspan="1" colspan="1">6.80 (6.25; 7.50)</td>
<td align="left" rowspan="1" colspan="1">9.00 (8.05; 9.50)</td>
<td align="left" rowspan="1" colspan="1"><.0001</td>
<td align="left" rowspan="1" colspan="1">5.03 (4.32; 5.75)</td>
<td align="left" rowspan="1" colspan="1">7.30 (6.55; 8.00)</td>
<td align="left" rowspan="1" colspan="1">9.30 (8.75; 9.80)</td>
<td align="left" rowspan="1" colspan="1"><.0001</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"><bold>Socioeconomic/-demographic data</bold>
</td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"></td>
</tr>
<tr><td align="left" rowspan="1" colspan="1">Age (years)</td>
<td align="left" rowspan="1" colspan="1">50.9 (47.7; 54.8)</td>
<td align="left" rowspan="1" colspan="1">51.7 (48.6; 55.8)</td>
<td align="left" rowspan="1" colspan="1">53.4 (48.9; 57.1)</td>
<td align="left" rowspan="1" colspan="1"><.0001</td>
<td align="left" rowspan="1" colspan="1">48.8 (46.8; 54.5)</td>
<td align="left" rowspan="1" colspan="1">49.9 (47.2; 55.0)</td>
<td align="left" rowspan="1" colspan="1">52.3 (48.4; 56.5)</td>
<td align="left" rowspan="1" colspan="1">0.006</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1">Education level (%)</td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1">0.1</td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1">0.1</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"><italic>Primary education</italic>
</td>
<td align="left" rowspan="1" colspan="1">34.9</td>
<td align="left" rowspan="1" colspan="1">25.8</td>
<td align="left" rowspan="1" colspan="1">25.3</td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1">42.5</td>
<td align="left" rowspan="1" colspan="1">27.8</td>
<td align="left" rowspan="1" colspan="1">23.9</td>
<td align="left" rowspan="1" colspan="1"></td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"><italic>High school diploma</italic>
</td>
<td align="left" rowspan="1" colspan="1">32.3</td>
<td align="left" rowspan="1" colspan="1">38.1</td>
<td align="left" rowspan="1" colspan="1">36.9</td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1">37.5</td>
<td align="left" rowspan="1" colspan="1">36.9</td>
<td align="left" rowspan="1" colspan="1">39.4</td>
<td align="left" rowspan="1" colspan="1"></td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"><italic>University level or equivalent</italic>
</td>
<td align="left" rowspan="1" colspan="1">32.8</td>
<td align="left" rowspan="1" colspan="1">36.1</td>
<td align="left" rowspan="1" colspan="1">37.8</td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1">20.0</td>
<td align="left" rowspan="1" colspan="1">35.3</td>
<td align="left" rowspan="1" colspan="1">36.8</td>
<td align="left" rowspan="1" colspan="1"></td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"><bold>Lifestyle factors</bold>
</td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"></td>
</tr>
<tr><td align="left" rowspan="1" colspan="1">Tobacco use status (%)</td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1">0.02</td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1">0.09</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"><italic>Non-smoker</italic>
</td>
<td align="left" rowspan="1" colspan="1">26.2</td>
<td align="left" rowspan="1" colspan="1">31.0</td>
<td align="left" rowspan="1" colspan="1">36.9</td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1">62.5</td>
<td align="left" rowspan="1" colspan="1">65.1</td>
<td align="left" rowspan="1" colspan="1">63.2</td>
<td align="left" rowspan="1" colspan="1"></td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"><italic>Former smoker</italic>
</td>
<td align="left" rowspan="1" colspan="1">57.4</td>
<td align="left" rowspan="1" colspan="1">56.0</td>
<td align="left" rowspan="1" colspan="1">55.6</td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1">20.0</td>
<td align="left" rowspan="1" colspan="1">27.5</td>
<td align="left" rowspan="1" colspan="1">31.6</td>
<td align="left" rowspan="1" colspan="1"></td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"><italic>Smoker</italic>
</td>
<td align="left" rowspan="1" colspan="1">16.4</td>
<td align="left" rowspan="1" colspan="1">13.0</td>
<td align="left" rowspan="1" colspan="1">7.5</td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1">17.5</td>
<td align="left" rowspan="1" colspan="1">7.5</td>
<td align="left" rowspan="1" colspan="1">5.2</td>
<td align="left" rowspan="1" colspan="1"></td>
</tr>
<tr><td align="left" rowspan="1" colspan="1">Physical activity level (%)</td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"><.0001</td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"><.0001</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"><italic>30 min walk per day</italic>
<xref ref-type="table-fn" rid="nt118">3</xref>
</td>
<td align="left" rowspan="1" colspan="1">88.7</td>
<td align="left" rowspan="1" colspan="1">51.3</td>
<td align="left" rowspan="1" colspan="1">19.1</td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1">90.0</td>
<td align="left" rowspan="1" colspan="1">72.9</td>
<td align="left" rowspan="1" colspan="1">46.5</td>
<td align="left" rowspan="1" colspan="1"></td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"><italic>30–60 min walk per day</italic>
<xref ref-type="table-fn" rid="nt118">3</xref>
</td>
<td align="left" rowspan="1" colspan="1">8.2</td>
<td align="left" rowspan="1" colspan="1">26.0</td>
<td align="left" rowspan="1" colspan="1">30.3</td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1">10.0</td>
<td align="left" rowspan="1" colspan="1">17.7</td>
<td align="left" rowspan="1" colspan="1">25.2</td>
<td align="left" rowspan="1" colspan="1"></td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"><italic>>60 min walk per day</italic>
<xref ref-type="table-fn" rid="nt118">3</xref>
</td>
<td align="left" rowspan="1" colspan="1">3.1</td>
<td align="left" rowspan="1" colspan="1">22.8</td>
<td align="left" rowspan="1" colspan="1">50.6</td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1">0.0</td>
<td align="left" rowspan="1" colspan="1">9.4</td>
<td align="left" rowspan="1" colspan="1">28.4</td>
<td align="left" rowspan="1" colspan="1"></td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"><bold>Anthropometric data</bold>
</td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"></td>
</tr>
<tr><td align="left" rowspan="1" colspan="1">BMI (kg/m<sup>2</sup>
)</td>
<td align="left" rowspan="1" colspan="1">26.9 (25.7; 29.0)</td>
<td align="left" rowspan="1" colspan="1">27.1 (25.9; 28.7)</td>
<td align="left" rowspan="1" colspan="1">26.8 (25.8; 28.4)</td>
<td align="left" rowspan="1" colspan="1">0.3</td>
<td align="left" rowspan="1" colspan="1">27.9 (26.6; 30.4)</td>
<td align="left" rowspan="1" colspan="1">27.6 (25.9; 30.9)</td>
<td align="left" rowspan="1" colspan="1">26.7 (25.8; 28.5)</td>
<td align="left" rowspan="1" colspan="1">0.006</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1">BMI ≥30 kg/m<sup>2</sup>
(%)</td>
<td align="left" rowspan="1" colspan="1">16.4</td>
<td align="left" rowspan="1" colspan="1">13.5</td>
<td align="left" rowspan="1" colspan="1">12.0</td>
<td align="left" rowspan="1" colspan="1">0.4</td>
<td align="left" rowspan="1" colspan="1">30.0</td>
<td align="left" rowspan="1" colspan="1">30.2</td>
<td align="left" rowspan="1" colspan="1">14.8</td>
<td align="left" rowspan="1" colspan="1">0.002</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1">WC (cm)<xref ref-type="table-fn" rid="nt119">4</xref>
</td>
<td align="left" rowspan="1" colspan="1">96.0 (92.0; 101.0)</td>
<td align="left" rowspan="1" colspan="1">96.0 (91.0; 101.0)</td>
<td align="left" rowspan="1" colspan="1">95.0 (90.0; 99.0)</td>
<td align="left" rowspan="1" colspan="1">0.03</td>
<td align="left" rowspan="1" colspan="1">88.0 (82.5; 96.5)</td>
<td align="left" rowspan="1" colspan="1">87.0 (82.0; 94.0)</td>
<td align="left" rowspan="1" colspan="1">84.0 (80.0; 90.0)</td>
<td align="left" rowspan="1" colspan="1">0.0005</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1">Abdominal adiposity (%)<xref ref-type="table-fn" rid="nt119">4,5</xref>
</td>
<td align="left" rowspan="1" colspan="1">20.0</td>
<td align="left" rowspan="1" colspan="1">17.9</td>
<td align="left" rowspan="1" colspan="1">13.7</td>
<td align="left" rowspan="1" colspan="1">0.2</td>
<td align="left" rowspan="1" colspan="1">45.0</td>
<td align="left" rowspan="1" colspan="1">43.9</td>
<td align="left" rowspan="1" colspan="1">30.3</td>
<td align="left" rowspan="1" colspan="1">0.02</td>
</tr>
</tbody>
</table>
</alternatives>
<table-wrap-foot><fn id="nt113"><label></label>
<p>SU.VI.MAX Study, France, 1994–1996.</p>
</fn>
<fn id="nt114"><label></label>
<p>PNNS-GS: Programme National Nutrition Santé Guideline Score. Categories of the PNNS-GS: Low: <6 points; medium: ≥6 and <9 points; high: ≥9 points.</p>
</fn>
<fn id="nt115"><label></label>
<p>BMI: body mass index. WC: waist circumference.</p>
</fn>
<fn id="nt116"><label>1</label>
<p>Values are medians (quartile 1; quartile 3) or frequencies.</p>
</fn>
<fn id="nt117"><label>2</label>
<p>Kruskal-Wallis-test for continuous variables and Chi<sup>2</sup>
-test for categorical variables.</p>
</fn>
<fn id="nt118"><label>3</label>
<p>On at least five days of the week.</p>
</fn>
<fn id="nt119"><label>4</label>
<p>Data on WC was only available for 878 men and 391 women.</p>
</fn>
<fn id="nt120"><label>5</label>
<p>Word Health Organization cut-off for a substantially increased risk of metabolic Complications (for Caucasians): >102 cm (men); >88 cm (women) <xref rid="pone.0087083-Alberti1" ref-type="bibr">[53]</xref>
.</p>
</fn>
</table-wrap-foot>
</table-wrap>
</sec>
<sec id="s3c"><title>PNNS-GS in relation to anthropometric changes</title>
<p><xref ref-type="table" rid="pone-0087083-t004"><bold>Table 4</bold>
</xref>
shows 6-year changes in weight and waist circumference in relation to categories of the PNNS-GS by gender. Men with a high PNNS-GS had a significantly lower 6-year-weight-gain as compared to men with a low PNNS-GS. Adjusted means in the fully-adjusted analysis were 3.63% [95% confidence interval: 2.87%; 4.39%] vs. 2.10% [1.39%; 2.81%]; p = 0.01. No association was observed in women. Moreover, there were no significant relations between the PNNS-GS and change in WC among either men or women.</p>
<table-wrap id="pone-0087083-t004" orientation="portrait" position="float"><object-id pub-id-type="doi">10.1371/journal.pone.0087083.t004</object-id>
<label>Table 4</label>
<caption><title>Six-year anthropometric changes according to categories of the Programme National Nutrition Santé Guideline Score (PNNS-GS), n = 1479.</title>
</caption>
<alternatives><graphic id="pone-0087083-t004-4" xlink:href="pone.0087083.t004"></graphic>
<table frame="hsides" rules="groups"><colgroup span="1"><col align="left" span="1"></col>
<col align="center" span="1"></col>
<col align="center" span="1"></col>
<col align="center" span="1"></col>
<col align="center" span="1"></col>
<col align="center" span="1"></col>
<col align="center" span="1"></col>
<col align="center" span="1"></col>
<col align="center" span="1"></col>
<col align="center" span="1"></col>
</colgroup>
<thead><tr><td align="left" rowspan="1" colspan="1"></td>
<td colspan="3" align="left" rowspan="1">Low PNNS-GS</td>
<td colspan="3" align="left" rowspan="1">Medium PNNS-GS</td>
<td colspan="2" align="left" rowspan="1">High PNNS-GS, ref.</td>
<td align="left" rowspan="1" colspan="1"></td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1">LSmean<xref ref-type="table-fn" rid="nt123">1</xref>
</td>
<td align="left" rowspan="1" colspan="1">95%-CI<xref ref-type="table-fn" rid="nt124">2</xref>
</td>
<td align="left" rowspan="1" colspan="1">p<xref ref-type="table-fn" rid="nt125">3</xref>
</td>
<td align="left" rowspan="1" colspan="1">LSmean<xref ref-type="table-fn" rid="nt123">1</xref>
</td>
<td align="left" rowspan="1" colspan="1">95%-CI<xref ref-type="table-fn" rid="nt124">2</xref>
</td>
<td align="left" rowspan="1" colspan="1">p<xref ref-type="table-fn" rid="nt125">3</xref>
</td>
<td align="left" rowspan="1" colspan="1">LSmean<xref ref-type="table-fn" rid="nt123">1</xref>
</td>
<td align="left" rowspan="1" colspan="1">95%-CI<xref ref-type="table-fn" rid="nt124">2</xref>
</td>
<td align="left" rowspan="1" colspan="1">overall p<xref ref-type="table-fn" rid="nt126">4</xref>
</td>
</tr>
</thead>
<tbody><tr><td colspan="10" align="left" rowspan="1"><bold>6-year-weight-change (%)</bold>
</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"><italic>Men (n = 1029)</italic>
</td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"><italic>(n = 195)</italic>
</td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"><italic>(n = 593)</italic>
</td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"><italic>(n = 241)</italic>
</td>
<td align="left" rowspan="1" colspan="1"></td>
</tr>
<tr><td align="left" rowspan="1" colspan="1">Model A<xref ref-type="table-fn" rid="nt127">5</xref>
</td>
<td align="left" rowspan="1" colspan="1">3.35</td>
<td align="left" rowspan="1" colspan="1">2.63; 4.06</td>
<td align="left" rowspan="1" colspan="1">0.002</td>
<td align="left" rowspan="1" colspan="1">2.23</td>
<td align="left" rowspan="1" colspan="1">1.82; 2.64</td>
<td align="left" rowspan="1" colspan="1">0.4</td>
<td align="left" rowspan="1" colspan="1">1.76</td>
<td align="left" rowspan="1" colspan="1">1.11; 2.40</td>
<td align="left" rowspan="1" colspan="1">0.004</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1">Model B<xref ref-type="table-fn" rid="nt128">6</xref>
</td>
<td align="left" rowspan="1" colspan="1">3.45</td>
<td align="left" rowspan="1" colspan="1">2.72; 4.19</td>
<td align="left" rowspan="1" colspan="1">0.002</td>
<td align="left" rowspan="1" colspan="1">2.21</td>
<td align="left" rowspan="1" colspan="1">1.80; 2.62</td>
<td align="left" rowspan="1" colspan="1">0.4</td>
<td align="left" rowspan="1" colspan="1">1.74</td>
<td align="left" rowspan="1" colspan="1">1.08; 2.39</td>
<td align="left" rowspan="1" colspan="1">0.003</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1">Model C<xref ref-type="table-fn" rid="nt129">7</xref>
</td>
<td align="left" rowspan="1" colspan="1">3.63</td>
<td align="left" rowspan="1" colspan="1">2.87; 4.39</td>
<td align="left" rowspan="1" colspan="1">0.007</td>
<td align="left" rowspan="1" colspan="1">2.51</td>
<td align="left" rowspan="1" colspan="1">2.05; 2.97</td>
<td align="left" rowspan="1" colspan="1">0.5</td>
<td align="left" rowspan="1" colspan="1">2.10</td>
<td align="left" rowspan="1" colspan="1">1.39; 2.81</td>
<td align="left" rowspan="1" colspan="1">0.01</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"><italic>Women (n = 450)</italic>
</td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"><italic>(n = 40)</italic>
</td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"><italic>(n = 255)</italic>
</td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"><italic>(n = 155)</italic>
</td>
<td align="left" rowspan="1" colspan="1"></td>
</tr>
<tr><td align="left" rowspan="1" colspan="1">Model A<xref ref-type="table-fn" rid="nt127">5</xref>
</td>
<td align="left" rowspan="1" colspan="1">1.70</td>
<td align="left" rowspan="1" colspan="1">−0.55; 3.96</td>
<td align="left" rowspan="1" colspan="1">0.3</td>
<td align="left" rowspan="1" colspan="1">2.63</td>
<td align="left" rowspan="1" colspan="1">1.73; 3.52</td>
<td align="left" rowspan="1" colspan="1">0.3</td>
<td align="left" rowspan="1" colspan="1">3.58</td>
<td align="left" rowspan="1" colspan="1">2.44; 4.73</td>
<td align="left" rowspan="1" colspan="1">0.2</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1">Model B<xref ref-type="table-fn" rid="nt128">6</xref>
</td>
<td align="left" rowspan="1" colspan="1">2.20</td>
<td align="left" rowspan="1" colspan="1">−0.08; 4.47</td>
<td align="left" rowspan="1" colspan="1">0.5</td>
<td align="left" rowspan="1" colspan="1">2.52</td>
<td align="left" rowspan="1" colspan="1">1.64; 3.40</td>
<td align="left" rowspan="1" colspan="1">0.2</td>
<td align="left" rowspan="1" colspan="1">3.63</td>
<td align="left" rowspan="1" colspan="1">2.49; 4.77</td>
<td align="left" rowspan="1" colspan="1">0.3</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1">Model C<xref ref-type="table-fn" rid="nt129">7, 8</xref>
</td>
<td align="left" rowspan="1" colspan="1">2.37</td>
<td align="left" rowspan="1" colspan="1">0.01; 4.73</td>
<td align="left" rowspan="1" colspan="1">0.5</td>
<td align="left" rowspan="1" colspan="1">2.79</td>
<td align="left" rowspan="1" colspan="1">1.64; 3.93</td>
<td align="left" rowspan="1" colspan="1">0.3</td>
<td align="left" rowspan="1" colspan="1">3.79</td>
<td align="left" rowspan="1" colspan="1">2.41; 5.17</td>
<td align="left" rowspan="1" colspan="1">0.3</td>
</tr>
<tr><td colspan="10" align="left" rowspan="1"><bold>6-year-change in WC (%)</bold>
<xref ref-type="table-fn" rid="nt131">9</xref>
</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"><italic>Men (n = 878)</italic>
</td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"><italic>(n = 157)</italic>
</td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"><italic>(n = 508)</italic>
</td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"><italic>(n = 213)</italic>
</td>
<td align="left" rowspan="1" colspan="1"></td>
</tr>
<tr><td align="left" rowspan="1" colspan="1">Model A<xref ref-type="table-fn" rid="nt127">5</xref>
</td>
<td align="left" rowspan="1" colspan="1">1.51</td>
<td align="left" rowspan="1" colspan="1">0.59; 2.43</td>
<td align="left" rowspan="1" colspan="1">0.3</td>
<td align="left" rowspan="1" colspan="1">1.09</td>
<td align="left" rowspan="1" colspan="1">0.57; 1.60</td>
<td align="left" rowspan="1" colspan="1">0.7</td>
<td align="left" rowspan="1" colspan="1">0.72</td>
<td align="left" rowspan="1" colspan="1">−0.08; 1.51</td>
<td align="left" rowspan="1" colspan="1">0.4</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1">Model B<xref ref-type="table-fn" rid="nt128">6</xref>
</td>
<td align="left" rowspan="1" colspan="1">1.67</td>
<td align="left" rowspan="1" colspan="1">0.72; 2.62</td>
<td align="left" rowspan="1" colspan="1">0.2</td>
<td align="left" rowspan="1" colspan="1">1.07</td>
<td align="left" rowspan="1" colspan="1">0.56; 1.58</td>
<td align="left" rowspan="1" colspan="1">0.6</td>
<td align="left" rowspan="1" colspan="1">0.64</td>
<td align="left" rowspan="1" colspan="1">−0.18; 1.45</td>
<td align="left" rowspan="1" colspan="1">0.3</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1">Model C<xref ref-type="table-fn" rid="nt129">7</xref>
</td>
<td align="left" rowspan="1" colspan="1">1.97</td>
<td align="left" rowspan="1" colspan="1">1.00; 2.94</td>
<td align="left" rowspan="1" colspan="1">0.3</td>
<td align="left" rowspan="1" colspan="1">1.49</td>
<td align="left" rowspan="1" colspan="1">0.92; 2.06</td>
<td align="left" rowspan="1" colspan="1">0.6</td>
<td align="left" rowspan="1" colspan="1">1.10</td>
<td align="left" rowspan="1" colspan="1">0.23; 1.97</td>
<td align="left" rowspan="1" colspan="1">0.4</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"><italic>Women (n = 391)</italic>
</td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"><italic>(n = 34)</italic>
</td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"><italic>(n = 221)</italic>
</td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"><italic>(n = 136)</italic>
</td>
<td align="left" rowspan="1" colspan="1"></td>
</tr>
<tr><td align="left" rowspan="1" colspan="1">Model A<xref ref-type="table-fn" rid="nt127">5</xref>
</td>
<td align="left" rowspan="1" colspan="1">1.30</td>
<td align="left" rowspan="1" colspan="1">−1.48; 4.08</td>
<td align="left" rowspan="1" colspan="1">0.4</td>
<td align="left" rowspan="1" colspan="1">1.85</td>
<td align="left" rowspan="1" colspan="1">0.76; 2.94</td>
<td align="left" rowspan="1" colspan="1">0.3</td>
<td align="left" rowspan="1" colspan="1">3.14</td>
<td align="left" rowspan="1" colspan="1">1.75; 4.53</td>
<td align="left" rowspan="1" colspan="1">0.3</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1">Model B<xref ref-type="table-fn" rid="nt128">6</xref>
</td>
<td align="left" rowspan="1" colspan="1">2.12</td>
<td align="left" rowspan="1" colspan="1">−0.73; 4.97</td>
<td align="left" rowspan="1" colspan="1">0.8</td>
<td align="left" rowspan="1" colspan="1">1.83</td>
<td align="left" rowspan="1" colspan="1">0.75; 2.92</td>
<td align="left" rowspan="1" colspan="1">0.4</td>
<td align="left" rowspan="1" colspan="1">2.97</td>
<td align="left" rowspan="1" colspan="1">1.57; 4.37</td>
<td align="left" rowspan="1" colspan="1">0.5</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1">Model C<xref ref-type="table-fn" rid="nt129">7, 8</xref>
</td>
<td align="left" rowspan="1" colspan="1">2.31</td>
<td align="left" rowspan="1" colspan="1">−0.68; 5.29</td>
<td align="left" rowspan="1" colspan="1">0.8</td>
<td align="left" rowspan="1" colspan="1">1.99</td>
<td align="left" rowspan="1" colspan="1">0.55; 3.43</td>
<td align="left" rowspan="1" colspan="1">0.4</td>
<td align="left" rowspan="1" colspan="1">3.15</td>
<td align="left" rowspan="1" colspan="1">1.44; 4.86</td>
<td align="left" rowspan="1" colspan="1">0.5</td>
</tr>
</tbody>
</table>
</alternatives>
<table-wrap-foot><fn id="nt121"><label></label>
<p>SU.VI.MAX study, France, 1994–2002.</p>
</fn>
<fn id="nt122"><label></label>
<p>Categories of the PNNS-GS: Low: <6 points; medium: ≥6 and <9 points; high: ≥9 points.</p>
</fn>
<fn id="nt123"><label>1</label>
<p>Least-squares mean.</p>
</fn>
<fn id="nt124"><label>2</label>
<p>95%- confidence interval (corrected according to Dunnett).</p>
</fn>
<fn id="nt125"><label>3</label>
<p>T-test with Dunnett correction.</p>
</fn>
<fn id="nt126"><label>4</label>
<p>Overall F-test (analysis of variance and covariance model).</p>
</fn>
<fn id="nt127"><label>5</label>
<p>Unadjusted.</p>
</fn>
<fn id="nt128"><label>6</label>
<p>Adjusted for age, energy intake.</p>
</fn>
<fn id="nt129"><label>7</label>
<p>Model B + adjustment for supplementation group, number of dietary records, initial height, education level, smoking, menopausal status (women).</p>
</fn>
<fn id="nt130"><label>8</label>
<p>Presented for illustrative purposes, but to be interpreted with caution (high number of adjustment variables/small number of women with a low PNNS-GS).</p>
</fn>
<fn id="nt131"><label>9</label>
<p>WC: waist circumference. Measures of WC at baseline and follow-up were only available for 878 male and 391 female participants.</p>
</fn>
</table-wrap-foot>
</table-wrap>
</sec>
<sec id="s3d"><title>mPNNS-GS in relation to anthropometric changes</title>
<p>Associations between 6-year anthropometric changes and the modified PNNS-GS are presented in <xref ref-type="table" rid="pone-0087083-t005"><bold>Table 5</bold>
</xref>
. Again, high dietary quality (mPNNS-GS ≥8.5 points) was related to lower gains in weight as compared to low dietary quality (mPNNS-GS <5 points) among men. The results obtained were very similar to those for the PNNS-GS, with adjusted means being 3.50% [2.72%; 4.28%] vs. 2.03% [1.24%; 2.82%]; p = 0.03. In women, mPNNS-GS and weight change were not related. Moreover, there was no significant association between the mPNNS-GS and changes in WC among either sex.</p>
<table-wrap id="pone-0087083-t005" orientation="portrait" position="float"><object-id pub-id-type="doi">10.1371/journal.pone.0087083.t005</object-id>
<label>Table 5</label>
<caption><title>Six-year anthropometric changes according to categories of the modified Programme National Nutrition Santé Guideline Score (mPNNS-GS), n = 1479.</title>
</caption>
<alternatives><graphic id="pone-0087083-t005-5" xlink:href="pone.0087083.t005"></graphic>
<table frame="hsides" rules="groups"><colgroup span="1"><col align="left" span="1"></col>
<col align="center" span="1"></col>
<col align="center" span="1"></col>
<col align="center" span="1"></col>
<col align="center" span="1"></col>
<col align="center" span="1"></col>
<col align="center" span="1"></col>
<col align="center" span="1"></col>
<col align="center" span="1"></col>
<col align="center" span="1"></col>
</colgroup>
<thead><tr><td align="left" rowspan="1" colspan="1"></td>
<td colspan="3" align="left" rowspan="1">Low mPNNS-GS</td>
<td colspan="3" align="left" rowspan="1">Medium mPNNS-GS</td>
<td colspan="2" align="left" rowspan="1">High mPNNS-GS, ref.</td>
<td align="left" rowspan="1" colspan="1"></td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1">LSmean<xref ref-type="table-fn" rid="nt134">1</xref>
</td>
<td align="left" rowspan="1" colspan="1">95%-CI<xref ref-type="table-fn" rid="nt135">2</xref>
</td>
<td align="left" rowspan="1" colspan="1">p<xref ref-type="table-fn" rid="nt136">3</xref>
</td>
<td align="left" rowspan="1" colspan="1">LSmean<xref ref-type="table-fn" rid="nt134">1</xref>
</td>
<td align="left" rowspan="1" colspan="1">95%-CI<xref ref-type="table-fn" rid="nt135">2</xref>
</td>
<td align="left" rowspan="1" colspan="1">p<xref ref-type="table-fn" rid="nt136">3</xref>
</td>
<td align="left" rowspan="1" colspan="1">LSmean<xref ref-type="table-fn" rid="nt134">1</xref>
</td>
<td align="left" rowspan="1" colspan="1">95%-CI<xref ref-type="table-fn" rid="nt135">2</xref>
</td>
<td align="left" rowspan="1" colspan="1">overall p<xref ref-type="table-fn" rid="nt137">4</xref>
</td>
</tr>
</thead>
<tbody><tr><td colspan="10" align="left" rowspan="1"><bold>6-year-weight-change (%)</bold>
</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"><italic>Men (n = 1029)</italic>
</td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"><italic>(n = 200)</italic>
</td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"><italic>(n = 636)</italic>
</td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"><italic>(n = 193)</italic>
</td>
<td align="left" rowspan="1" colspan="1"></td>
</tr>
<tr><td align="left" rowspan="1" colspan="1">Model A<xref ref-type="table-fn" rid="nt138">5</xref>
</td>
<td align="left" rowspan="1" colspan="1">3.04</td>
<td align="left" rowspan="1" colspan="1">2.33; 3.75</td>
<td align="left" rowspan="1" colspan="1">0.02</td>
<td align="left" rowspan="1" colspan="1">2.29</td>
<td align="left" rowspan="1" colspan="1">1.89; 2.69</td>
<td align="left" rowspan="1" colspan="1">0.3</td>
<td align="left" rowspan="1" colspan="1">1.75</td>
<td align="left" rowspan="1" colspan="1">1.02; 2.47</td>
<td align="left" rowspan="1" colspan="1">0.04</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1">Model B<xref ref-type="table-fn" rid="nt139">6</xref>
</td>
<td align="left" rowspan="1" colspan="1">3.27</td>
<td align="left" rowspan="1" colspan="1">2.52; 4.02</td>
<td align="left" rowspan="1" colspan="1">0.007</td>
<td align="left" rowspan="1" colspan="1">2.24</td>
<td align="left" rowspan="1" colspan="1">1.85; 2.64</td>
<td align="left" rowspan="1" colspan="1">0.3</td>
<td align="left" rowspan="1" colspan="1">1.67</td>
<td align="left" rowspan="1" colspan="1">0.93; 2.40</td>
<td align="left" rowspan="1" colspan="1">0.01</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1">Model C<xref ref-type="table-fn" rid="nt140">7</xref>
</td>
<td align="left" rowspan="1" colspan="1">3.50</td>
<td align="left" rowspan="1" colspan="1">2.72; 4.28</td>
<td align="left" rowspan="1" colspan="1">0.02</td>
<td align="left" rowspan="1" colspan="1">2.55</td>
<td align="left" rowspan="1" colspan="1">2.10; 3.00</td>
<td align="left" rowspan="1" colspan="1">0.3</td>
<td align="left" rowspan="1" colspan="1">2.03</td>
<td align="left" rowspan="1" colspan="1">1.24; 2.82</td>
<td align="left" rowspan="1" colspan="1">0.03</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"><italic>Women (n = 450)</italic>
</td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"><italic>(n = 29)</italic>
</td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"><italic>(n = 263)</italic>
</td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"><italic>(n = 158)</italic>
</td>
<td align="left" rowspan="1" colspan="1"></td>
</tr>
<tr><td align="left" rowspan="1" colspan="1">Model A<xref ref-type="table-fn" rid="nt138">5</xref>
</td>
<td align="left" rowspan="1" colspan="1">0.56</td>
<td align="left" rowspan="1" colspan="1">−2.08; 3.20</td>
<td align="left" rowspan="1" colspan="1">0.1</td>
<td align="left" rowspan="1" colspan="1">2.70</td>
<td align="left" rowspan="1" colspan="1">1.82; 3.57</td>
<td align="left" rowspan="1" colspan="1">0.4</td>
<td align="left" rowspan="1" colspan="1">3.60</td>
<td align="left" rowspan="1" colspan="1">2.46; 4.73</td>
<td align="left" rowspan="1" colspan="1">0.1</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1">Model B<xref ref-type="table-fn" rid="nt139">6</xref>
</td>
<td align="left" rowspan="1" colspan="1">0.59</td>
<td align="left" rowspan="1" colspan="1">−2.10; 3.29</td>
<td align="left" rowspan="1" colspan="1">0.1</td>
<td align="left" rowspan="1" colspan="1">2.52</td>
<td align="left" rowspan="1" colspan="1">1.63; 3.41</td>
<td align="left" rowspan="1" colspan="1">0.3</td>
<td align="left" rowspan="1" colspan="1">3.47</td>
<td align="left" rowspan="1" colspan="1">2.33; 4.61</td>
<td align="left" rowspan="1" colspan="1">0.1</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1">Model C<xref ref-type="table-fn" rid="nt140">7, 8</xref>
</td>
<td align="left" rowspan="1" colspan="1">0.46</td>
<td align="left" rowspan="1" colspan="1">−2.33; 3.25</td>
<td align="left" rowspan="1" colspan="1">0.1</td>
<td align="left" rowspan="1" colspan="1">2.79</td>
<td align="left" rowspan="1" colspan="1">1.63; 3.96</td>
<td align="left" rowspan="1" colspan="1">0.4</td>
<td align="left" rowspan="1" colspan="1">3.70</td>
<td align="left" rowspan="1" colspan="1">2.31; 5.08</td>
<td align="left" rowspan="1" colspan="1">0.1</td>
</tr>
<tr><td colspan="10" align="left" rowspan="1"><bold>6-year-change in WC (%)</bold>
<xref ref-type="table-fn" rid="nt142">9</xref>
</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"><italic>Men (n = 878)</italic>
</td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"><italic>(n = 160)</italic>
</td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"><italic>(n = 542)</italic>
</td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"><italic>(n = 176)</italic>
</td>
<td align="left" rowspan="1" colspan="1"></td>
</tr>
<tr><td align="left" rowspan="1" colspan="1">Model A<xref ref-type="table-fn" rid="nt138">5</xref>
</td>
<td align="left" rowspan="1" colspan="1">1.25</td>
<td align="left" rowspan="1" colspan="1">0.34; 2.16</td>
<td align="left" rowspan="1" colspan="1">0.5</td>
<td align="left" rowspan="1" colspan="1">1.17</td>
<td align="left" rowspan="1" colspan="1">0.67; 1.66</td>
<td align="left" rowspan="1" colspan="1">0.4</td>
<td align="left" rowspan="1" colspan="1">0.62</td>
<td align="left" rowspan="1" colspan="1">−0.25; 1.49</td>
<td align="left" rowspan="1" colspan="1">0.5</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1">Model B<xref ref-type="table-fn" rid="nt139">6</xref>
</td>
<td align="left" rowspan="1" colspan="1">1.49</td>
<td align="left" rowspan="1" colspan="1">0.53; 2.46</td>
<td align="left" rowspan="1" colspan="1">0.3</td>
<td align="left" rowspan="1" colspan="1">1.13</td>
<td align="left" rowspan="1" colspan="1">0.63; 1.63</td>
<td align="left" rowspan="1" colspan="1">0.4</td>
<td align="left" rowspan="1" colspan="1">0.51</td>
<td align="left" rowspan="1" colspan="1">−0.38; 1.41</td>
<td align="left" rowspan="1" colspan="1">0.3</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1">Model C<xref ref-type="table-fn" rid="nt140">7</xref>
</td>
<td align="left" rowspan="1" colspan="1">1.91</td>
<td align="left" rowspan="1" colspan="1">0.92; 2.90</td>
<td align="left" rowspan="1" colspan="1">0.3</td>
<td align="left" rowspan="1" colspan="1">1.54</td>
<td align="left" rowspan="1" colspan="1">0.98; 2.10</td>
<td align="left" rowspan="1" colspan="1">0.4</td>
<td align="left" rowspan="1" colspan="1">0.94</td>
<td align="left" rowspan="1" colspan="1">−0.02; 1.89</td>
<td align="left" rowspan="1" colspan="1">0.4</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1"><italic>Women (n = 391)</italic>
</td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"><italic>(n = 25)</italic>
</td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"><italic>(n = 225)</italic>
</td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"></td>
<td align="left" rowspan="1" colspan="1"><italic>(n = 141)</italic>
</td>
<td align="left" rowspan="1" colspan="1"></td>
</tr>
<tr><td align="left" rowspan="1" colspan="1">Model A<xref ref-type="table-fn" rid="nt138">5</xref>
</td>
<td align="left" rowspan="1" colspan="1">1.04</td>
<td align="left" rowspan="1" colspan="1">−2.20; 4.27</td>
<td align="left" rowspan="1" colspan="1">0.4</td>
<td align="left" rowspan="1" colspan="1">1.74</td>
<td align="left" rowspan="1" colspan="1">0.66; 2.82</td>
<td align="left" rowspan="1" colspan="1">0.2</td>
<td align="left" rowspan="1" colspan="1">3.29</td>
<td align="left" rowspan="1" colspan="1">1.92; 4.65</td>
<td align="left" rowspan="1" colspan="1">0.2</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1">Model B<xref ref-type="table-fn" rid="nt139">6</xref>
</td>
<td align="left" rowspan="1" colspan="1">1.93</td>
<td align="left" rowspan="1" colspan="1">−1.46; 5.33</td>
<td align="left" rowspan="1" colspan="1">0.8</td>
<td align="left" rowspan="1" colspan="1">1.75</td>
<td align="left" rowspan="1" colspan="1">0.65; 2.86</td>
<td align="left" rowspan="1" colspan="1">0.2</td>
<td align="left" rowspan="1" colspan="1">3.10</td>
<td align="left" rowspan="1" colspan="1">1.71; 4.49</td>
<td align="left" rowspan="1" colspan="1">0.3</td>
</tr>
<tr><td align="left" rowspan="1" colspan="1">Model C<xref ref-type="table-fn" rid="nt140">7, 8</xref>
</td>
<td align="left" rowspan="1" colspan="1">2.01</td>
<td align="left" rowspan="1" colspan="1">−1.52; 5.53</td>
<td align="left" rowspan="1" colspan="1">0.7</td>
<td align="left" rowspan="1" colspan="1">1.93</td>
<td align="left" rowspan="1" colspan="1">0.47; 3.40</td>
<td align="left" rowspan="1" colspan="1">0.2</td>
<td align="left" rowspan="1" colspan="1">3.30</td>
<td align="left" rowspan="1" colspan="1">1.60; 5.00</td>
<td align="left" rowspan="1" colspan="1">0.3</td>
</tr>
</tbody>
</table>
</alternatives>
<table-wrap-foot><fn id="nt132"><label></label>
<p>SU.VI.MAX study, France, 1994–2002.</p>
</fn>
<fn id="nt133"><label></label>
<p>Categories of the mPNNS-GS: Low: <5.5 points; medium: ≥5.5 and <8.5 points; high: ≥8.5 points.</p>
</fn>
<fn id="nt134"><label>1</label>
<p>Least-squares mean.</p>
</fn>
<fn id="nt135"><label>2</label>
<p>95%- confidence interval (corrected according to Dunnett).</p>
</fn>
<fn id="nt136"><label>3</label>
<p>T-test with Dunnett correction.</p>
</fn>
<fn id="nt137"><label>4</label>
<p>Overall F-test (analysis of variance and covariance model).</p>
</fn>
<fn id="nt138"><label>5</label>
<p>Unadjusted.</p>
</fn>
<fn id="nt139"><label>6</label>
<p>Adjusted for age, energy intake, and physical activity (<30 min of walk per day vs. ≥30 min of walk per day).</p>
</fn>
<fn id="nt140"><label>7</label>
<p>Model B + adjustment for supplementation group, number of dietary records, initial height, education level, smoking, menopausal status (women).</p>
</fn>
<fn id="nt141"><label>8</label>
<p>Presented for illustrative purposes, but to be interpreted with caution (high number of adjustment variables/small number of women with a low mPNNS-GS).</p>
</fn>
<fn id="nt142"><label>9</label>
<p>WC: waist circumference. Measures of WC at baseline and follow-up were only available for 878 male and 391 female participants.</p>
</fn>
</table-wrap-foot>
</table-wrap>
</sec>
</sec>
<sec sec-type="discussion" id="s4"><title>Discussion</title>
<p>In this sample of French middle-aged overweight and obese adults, participants generally gained weight (on average 2.50%) over a 6-year period. However, men with a low dietary quality (low mPNNS-GS) gained more weight over time than those with a high dietary quality. The same was true for men with a low level of diet quality and physical activity combined (low PNNS-GS).</p>
<p>To the best of our knowledge, our study is the first to specifically investigate the relation of a priori- defined diet quality with anthropometric changes among overweight or obese subjects. However, two studies do provide information on the role of changes in empirically defined dietary patterns in the larger context of secondary obesity prevention. In the Swedish Mammography Cohort, the beneficial role of a “healthy pattern” was stronger among obese women (mean age: 54.2 years) than among normal-weight or overweight women <xref rid="pone.0087083-Newby1" ref-type="bibr">[35]</xref>
. Moreover, Japanese participants of a health promotion program (mean age ≈60 years) aimed at weight reduction achieved especially high losses in weight when changing their eating habits from a “sweets, meats, dairy products and alcohol”-pattern to a “plant foods and seafoods”-pattern and when maintaining a “plant foods and seafoods”-pattern <xref rid="pone.0087083-Nakade1" ref-type="bibr">[36]</xref>
.</p>
<p>The other available longitudinal studies investigating diet quality in relation to anthropometric outcomes considered either anthropometric changes in mixed samples of participants (normal weight, overweight, and obese subjects considered together) <xref rid="pone.0087083-Beunza1" ref-type="bibr">[11]</xref>
–<xref rid="pone.0087083-Zamora1" ref-type="bibr">[16]</xref>
, <xref rid="pone.0087083-Lassale1" ref-type="bibr">[19]</xref>
, <xref rid="pone.0087083-KesseGuyot1" ref-type="bibr">[20]</xref>
, or the risk of becoming overweight or obese within samples of normal-weight participants <xref rid="pone.0087083-Beunza1" ref-type="bibr">[11]</xref>
, <xref rid="pone.0087083-Gao1" ref-type="bibr">[12]</xref>
, <xref rid="pone.0087083-Wolongevicz1" ref-type="bibr">[17]</xref>
–<xref rid="pone.0087083-KesseGuyot1" ref-type="bibr">[20]</xref>
. Overall, studies investigating the association of scores reflecting adherence to nutritional guidelines with anthropometric changes support a favorable role of high dietary quality, in line with our results concerning men (despite some inconsistency <xref rid="pone.0087083-Gao1" ref-type="bibr">[12]</xref>
, <xref rid="pone.0087083-Kimokoti1" ref-type="bibr">[14]</xref>
, <xref rid="pone.0087083-Zamora1" ref-type="bibr">[16]</xref>
). In particular, two previous investigations of the SU.VI.MAX study showed a favorable role of higher PNNS-GS scores in terms of changes in body weight over different periods of time (6 years <xref rid="pone.0087083-KesseGuyot1" ref-type="bibr">[20]</xref>
and 13 years <xref rid="pone.0087083-Lassale1" ref-type="bibr">[19]</xref>
, respectively). In an Australian cohort (age range: 25–75 years), higher adherence to national recommendations was related to lower weight gain among males <xref rid="pone.0087083-Arabshahi1" ref-type="bibr">[13]</xref>
, and in a US-study (mean age ≈52 years), better adherence to a subset of the Dietary Guidelines for Americans was inversely related to weight gain among males and females <xref rid="pone.0087083-Quatromoni1" ref-type="bibr">[15]</xref>
. Besides, studies investigating empirically derived food patterns in relation to anthropometric changes (without excluding participants with a BMI ≥25) consistently identified different types of ‘healthy patterns’ to predict smaller gains in weight, BMI or waist circumference <xref rid="pone.0087083-Newby1" ref-type="bibr">[35]</xref>
, <xref rid="pone.0087083-Newby2" ref-type="bibr">[37]</xref>
–<xref rid="pone.0087083-Newby3" ref-type="bibr">[39]</xref>
. The above-cited studies did not apply scores including a physical activity component, and correspond thus the most to our analyses concerning the mPNNS-GS. Of note, in our study, results for the mPNNS-GS and the PNNS-GS were very similar and physical activity was not significantly related to anthropometric changes (data not shown). This may be due to a potential bias caused by selective overreporting of physical activity by participants especially at risk of an unfavorable progression of overweight.</p>
<p>In our study, neither the mPNNS-GS nor the PNNS-GS were significantly related to anthropometric changes among women. In fact, women with a low diet quality even tended to gain less weight over time than women with a high diet quality. This unexpected relation was stronger for the mPNNS-GS than for the PNNS-GS as a higher physical activity tended to be associated with lower gains in weight among females (p for the crude association = 0.2; data not shown). Supplementary analyses conducted to understand the lack of an association among females revealed that 8 out of 9 (89%) women with a low mPNNS-GS had reduced their energy intake by ≥350 kcal (baseline energy intake compared to intake at the end of follow-up, within a subsample of 197 women with ≥3 dietary records at the end of follow-up). Among women with a high baseline mPNNS-GS, such drastic changes were only present in 15% (12/79). Concerning women with a low vs. a high PNNS-GS, the respective proportions were 56% (10/18) and 18% (14/80). Accordingly, our unexpected findings in women could, at least in part, be explained by an active reduction of caloric intake, particularly in those in the lowest diet quality group. Considering the age range of women in our sample, hormonal changes linked to menopause could have acted as a confounding factor. However, baseline menopausal status was not significantly related to weight change in our sample (p in an ANOVA model adjusted for baseline age = 0.5). Moreover, expressing weight change as an absolute value (follow-up weight – baseline weight) did not change the direction of our results for females, whether we adjusted for baseline weight or not (data not shown).</p>
<p>We conducted supplemental analyses in which we applied a more severe approach of excluding underreporters, using the Black/Goldberg method with physical activity level (PAL)- factors of 1.55, 1.70 and 1.85 (participants in the lowest, middle, and highest category of physical activity, respectively) <xref rid="pone.0087083-Black1" ref-type="bibr">[40]</xref>
. The choice of PAL-factors was oriented by a joint FAO/WHO/UNO- report <xref rid="pone.0087083-FAOWHOUNU1" ref-type="bibr">[41]</xref>
and the indications given by Black <xref rid="pone.0087083-Black1" ref-type="bibr">[40]</xref>
. In these analyses (with drastically reduced study samples of n = 301 women and n = 786 men), the unexpected results found for women were slightly less pronounced concerning weight change. Concerning change in WC, results were now in the ‘expected direction’ (women with a higher dietary quality gained slightly less WC over time than women with a lower dietary quality), but far from being statistically significant (n = 0.9). Our results concerning men were not substantially altered. In conclusion, underreporting by women especially at risk to gain weight may also partly explain our unexpected results for females.</p>
<p>Similar to our study, two previous studies have observed an association between dietary quality and anthropometric changes among men only <xref rid="pone.0087083-Arabshahi1" ref-type="bibr">[13]</xref>
, <xref rid="pone.0087083-Lassale1" ref-type="bibr">[19]</xref>
. Reverse causality in relation to dieting (a behavior much more frequent in women than in men <xref rid="pone.0087083-Timperio1" ref-type="bibr">[42]</xref>
) has been discussed as a probable explanation for this phenomenon <xref rid="pone.0087083-Arabshahi1" ref-type="bibr">[13]</xref>
. In prior investigations of data from SU.VI.MAX participants of all BMI categories, a beneficial role of the PNNS-GS among women was found concerning 6-year-anthropometric changes <xref rid="pone.0087083-KesseGuyot1" ref-type="bibr">[20]</xref>
, but not concerning 13-year-anthropometric changes <xref rid="pone.0087083-Lassale1" ref-type="bibr">[19]</xref>
. This underlines that identifying determinants of weight change among women may be especially problematic in populations of overweight or obese subjects and in studies with very long follow-up periods (leaving time for changes in dietary behavior). Concerning our data, the results regarding women should be considered with much caution.</p>
<p>Contrary to previous research <xref rid="pone.0087083-Gao1" ref-type="bibr">[12]</xref>
, <xref rid="pone.0087083-Arabshahi1" ref-type="bibr">[13]</xref>
, <xref rid="pone.0087083-Estaquio1" ref-type="bibr">[32]</xref>
, we did not observe any association between diet quality and WC, neither among men, nor among women. One possible reason is that measurement error is generally higher for WC than for weight <xref rid="pone.0087083-Ulijaszek1" ref-type="bibr">[43]</xref>
, especially among overweight and obese subjects <xref rid="pone.0087083-Nordhamn1" ref-type="bibr">[44]</xref>
. In addition, mean gain in WC was only 1.44% over the six years of follow-up, making it potentially difficult to detect differences between groups. Furthermore, baseline and follow-up measurements of WC were only available for 1269 of the 1497 subjects in our study sample. Thus, statistical power was greater in analyses on weight than in analyses on WC.</p>
<p>Concerning the public health relevance of our results, it has to be noted that the observed effect size of our main finding is rather small: men with a low PNNS-GS gained 3.63% of their initial weight over six years while men with a low PNNS-GS only gained 2.10% (data not shown), corresponding to a mean difference of 1.53%. Yet, on the population level, even minor shifts in adiposity indicators could have an impact on chronic disease incidence <xref rid="pone.0087083-Resnick1" ref-type="bibr">[45]</xref>
, <xref rid="pone.0087083-Czernichow1" ref-type="bibr">[46]</xref>
.</p>
<p>Several limitations of our study should be taken into consideration. First, the external validity of our results might be limited as the SU.VI.MAX cohort is a selected sample of compliant volunteers <xref rid="pone.0087083-Hercberg2" ref-type="bibr">[21]</xref>
. Notably, the study's participants may have had a lower the risk of weight gain as compared to the general population, and our sample may have been rather homogeneous in terms of diet quality.</p>
<p>Further selection bias could have occurred because of the high rates of exclusion of participants due to missing data (see <xref ref-type="fig" rid="pone-0087083-g001"><bold>Figure 1</bold>
</xref>
). While no sensitivity analysis could be conducted to assess potential bias due to exclusion of participants without measured baseline BMI, we did carry out supplemental analysis in order to account for possible bias due to the exclusion of subjects who had missing values on other variables (or incidents of chronic disease). Notably, these excluded subjects had a slightly higher self-declared BMI as compared to the subjects included into our analyses (see <xref ref-type="table" rid="pone-0087083-t002"><bold>Table 2</bold>
</xref>
). We applied the “inverse probability weighting” method <xref rid="pone.0087083-Seaman1" ref-type="bibr">[47]</xref>
–<xref rid="pone.0087083-Hofler1" ref-type="bibr">[49]</xref>
, consisting of two steps: The probability to be included in the present analysis was determined for each of the 2990 SU.VI.MAX participants who were overweight or obese and aged 45–60 years at baseline, using a logistic regression model with baseline characteristics as independent variables (missing values were dealt with by regression imputation). Then, data were reanalyzed using the inverse of these probabilities as weights. Weighted models yielded essentially the same results as our main models.</p>
<p>Secondly, most of the participants not included into our analysis because they were not overweight/obese at baseline were women (in line with the fact that less women than men have a BMI ≥25 in the French general population <xref rid="pone.0087083-InsermTNS1" ref-type="bibr">[50]</xref>
). This drastically reduced the proportion of women in our study sample and resulted in limited statistical power concerning the analyses on female participants.</p>
<p>Thirdly, the construction of predefined diet scores is prone to subjectivity, notably concerning the selection of components, cutoff values, and their scoring system <xref rid="pone.0087083-Waijers1" ref-type="bibr">[9]</xref>
. However, the PNNS-GS was created with the objective to closely reflect the entirety of French national guidelines, leaving less room for arbitrary choices, and has been shown to be a good predictor of nutritional status <xref rid="pone.0087083-Estaquio1" ref-type="bibr">[32]</xref>
. Fourthly, due to the observational design of our study, it is possible that our results are affected by residual confounding. In particular, we were not able to account for episodes of dieting or weight loss medication.</p>
<p>Important strengths of the present study include its prospective design and the high quality of anthropometric and dietary data: Anthropometric measurements were not self-reported but conducted in a standardized manner by trained technicians, strengthening their accuracy <xref rid="pone.0087083-ConnorGorber1" ref-type="bibr">[51]</xref>
. Dietary exposure was measured by repeated 24-h records, known to provide good estimates of intake at the individual level <xref rid="pone.0087083-Ma1" ref-type="bibr">[52]</xref>
. The availability of, on average, 10 records par participant permitted accounting for seasonal and weekly variability and thus assured a particularly high validity of dietary information. Moreover, the diet score applied in this study has the advantage that it accounts, unlike many other scores <xref rid="pone.0087083-Waijers1" ref-type="bibr">[9]</xref>
, for excess energy intake – a feature that is especially relevant when analyzing determinants of weight change (even if <bold><xref ref-type="supplementary-material" rid="pone.0087083.s001">Table S1</xref>
</bold>
shows that penalization did not have a very large impact on our results).</p>
<sec id="s4a"><title>Conclusion</title>
<p>In this sample of overweight and obese French middle-aged adults, a low adequacy of the diet to French nutritional recommendations was related to a higher long-term weight gain among men. Thus, our findings suggest that, in men, diet quality has a role in the progression of overweight or obesity and confirm the importance of programs aimed at increasing adherence to national dietary recommendations, such as the PNNS.</p>
</sec>
</sec>
<sec sec-type="supplementary-material" id="s5"><title>Supporting Information</title>
<supplementary-material content-type="local-data" id="pone.0087083.s001"><label>Table S1</label>
<caption><p><bold>Anthropometric changes according to categories of the unpenalized Programme National Nutrition Santé Guideline Score (PNNS-GS), n = 1479.</bold>
SU.VI.MAX study, France, 1994–2002. Categories of the (unpenalized) PNNS-GS: Low: <6 points; medium: ≥6 and <9 points; high: ≥9 points. <sup>1</sup>
Least-squares mean. <sup>2</sup>
95%- confidence interval (corrected according to Dunnett). <sup>3</sup>
T-test with Dunnett correction. <sup>4</sup>
Overall F-test (analysis of variance and covariance model). <sup>5</sup>
Unadjusted. <sup>6</sup>
Adjusted for age, energy intake. <sup>7</sup>
Model B + adjustment for supplementation group, number of dietary records, initial height, education level, smoking, menopausal status (women). <sup>8</sup>
Presented for illustrative purposes, but to be interpreted with caution (high number of adjustment variables/small number of women with a low PNNS-GS). <sup>9</sup>
WC: waist circumference. Measures of WC at baseline and follow-up were only available for 878 male and 391 female participants.</p>
<p>(DOC)</p>
</caption>
<media xlink:href="pone.0087083.s001.doc"><caption><p>Click here for additional data file.</p>
</caption>
</media>
</supplementary-material>
</sec>
</body>
<back><ack><p>We thank all the scientists who helped to carry out the SU.VI.MAX study and the teams that assisted in fieldwork, as well as all participants of the SU.VI.MAX study.</p>
</ack>
<ref-list><title>References</title>
<ref id="pone.0087083-Malik1"><label>1</label>
<mixed-citation publication-type="journal"><name><surname>Malik</surname>
<given-names>VS</given-names>
</name>
, <name><surname>Willett</surname>
<given-names>WC</given-names>
</name>
, <name><surname>Hu</surname>
<given-names>FB</given-names>
</name>
(<year>2013</year>
) <article-title>Global obesity: trends, risk factors and policy implications</article-title>
. <source>Nature Reviews Endocrinology</source>
<volume>9</volume>
: <fpage>13</fpage>
–<lpage>27</lpage>
</mixed-citation>
</ref>
<ref id="pone.0087083-Branca1"><label>2</label>
<mixed-citation publication-type="other">Branca F, Nikogosian H, Lobstein T (2007) The challenge of obesity in the WHO European Region and the strategies for response. Copenhagen: World Health Organization Europe.</mixed-citation>
</ref>
<ref id="pone.0087083-World1"><label>3</label>
<mixed-citation publication-type="other">World Health Organization (2003) Diet, nutrition and the prevention of chronic diseases. World Health Organization technical report series 916. Geneva: World Health Organization.</mixed-citation>
</ref>
<ref id="pone.0087083-World2"><label>4</label>
<mixed-citation publication-type="other">World Health Organization (2009) Global health risks: Mortality and burden of disease attributable to selected major risks. Geneva: World Health Organization.</mixed-citation>
</ref>
<ref id="pone.0087083-Painter1"><label>5</label>
<mixed-citation publication-type="journal"><name><surname>Painter</surname>
<given-names>J</given-names>
</name>
, <name><surname>Rah</surname>
<given-names>JH</given-names>
</name>
, <name><surname>Lee</surname>
<given-names>YK</given-names>
</name>
(<year>2002</year>
) <article-title>Comparison of international food guide pictorial representations</article-title>
. <source>Journal of the American Dietetic Association</source>
<volume>102</volume>
: <fpage>483</fpage>
–<lpage>489</lpage>
<pub-id pub-id-type="pmid">11985405</pub-id>
</mixed-citation>
</ref>
<ref id="pone.0087083-Bull1"><label>6</label>
<mixed-citation publication-type="journal"><name><surname>Bull</surname>
<given-names>FC</given-names>
</name>
, <name><surname>Bellew</surname>
<given-names>B</given-names>
</name>
, <name><surname>Schöppe</surname>
<given-names>S</given-names>
</name>
, <name><surname>Bauman</surname>
<given-names>AE</given-names>
</name>
(<year>2004</year>
) <article-title>Developments in National Physical Activity Policy: an international review and recommendations towards better practice</article-title>
. <source>J Sci Med Sport</source>
<volume>7</volume>
: <fpage>93</fpage>
–<lpage>104</lpage>
<pub-id pub-id-type="pmid">15214607</pub-id>
</mixed-citation>
</ref>
<ref id="pone.0087083-Hercberg1"><label>7</label>
<mixed-citation publication-type="journal"><name><surname>Hercberg</surname>
<given-names>S</given-names>
</name>
, <name><surname>Chat-Yung</surname>
<given-names>S</given-names>
</name>
, <name><surname>Chauliac</surname>
<given-names>M</given-names>
</name>
(<year>2008</year>
) <article-title>The French National Nutrition and Health Program: 2001-2006-2010</article-title>
. <source>International Journal of Public Health</source>
<volume>53</volume>
: <fpage>68</fpage>
–<lpage>77</lpage>
<pub-id pub-id-type="pmid">18681335</pub-id>
</mixed-citation>
</ref>
<ref id="pone.0087083-Hu1"><label>8</label>
<mixed-citation publication-type="journal"><name><surname>Hu</surname>
<given-names>FB</given-names>
</name>
(<year>2002</year>
) <article-title>Dietary pattern analysis: a new direction in nutritional epidemiology</article-title>
. <source>Current Opinion in Lipidology</source>
<volume>13</volume>
: <fpage>3</fpage>
–<lpage>9</lpage>
<pub-id pub-id-type="pmid">11790957</pub-id>
</mixed-citation>
</ref>
<ref id="pone.0087083-Waijers1"><label>9</label>
<mixed-citation publication-type="journal"><name><surname>Waijers</surname>
<given-names>PMCM</given-names>
</name>
, <name><surname>Feskens</surname>
<given-names>EJM</given-names>
</name>
, <name><surname>Ocke</surname>
<given-names>MC</given-names>
</name>
(<year>2007</year>
) <article-title>A critical review of predefined diet quality scores</article-title>
. <source>British Journal of Nutrition</source>
<volume>97</volume>
: <fpage>219</fpage>
–<lpage>231</lpage>
<pub-id pub-id-type="pmid">17298689</pub-id>
</mixed-citation>
</ref>
<ref id="pone.0087083-Wirt1"><label>10</label>
<mixed-citation publication-type="journal"><name><surname>Wirt</surname>
<given-names>A</given-names>
</name>
, <name><surname>Collins</surname>
<given-names>CE</given-names>
</name>
(<year>2009</year>
) <article-title>Diet quality – what is it and does it matter?</article-title>
<source>Public Health Nutrition</source>
<volume>12</volume>
: <fpage>2473</fpage>
–<lpage>2492</lpage>
<pub-id pub-id-type="pmid">19335941</pub-id>
</mixed-citation>
</ref>
<ref id="pone.0087083-Beunza1"><label>11</label>
<mixed-citation publication-type="journal"><name><surname>Beunza</surname>
<given-names>JJ</given-names>
</name>
, <name><surname>Toledo</surname>
<given-names>E</given-names>
</name>
, <name><surname>Hu</surname>
<given-names>FB</given-names>
</name>
, <name><surname>Rastrollo</surname>
<given-names>MB</given-names>
</name>
, <name><surname>Martinez</surname>
<given-names>MS</given-names>
</name>
, <etal>et al</etal>
(<year>2010</year>
) <article-title>Adherence to the Mediterranean diet, long-term weight change, and incident overweight or obesity the Seguimiento Universidad de Navarra (SUN) cohort</article-title>
. <source>American Journal of Clinical Nutrition</source>
<volume>92</volume>
: <fpage>1484</fpage>
–<lpage>1493</lpage>
<pub-id pub-id-type="pmid">20962161</pub-id>
</mixed-citation>
</ref>
<ref id="pone.0087083-Gao1"><label>12</label>
<mixed-citation publication-type="journal"><name><surname>Gao</surname>
<given-names>SK</given-names>
</name>
, <name><surname>Beresford</surname>
<given-names>SAA</given-names>
</name>
, <name><surname>Frank</surname>
<given-names>LL</given-names>
</name>
, <name><surname>Schreiner</surname>
<given-names>PJ</given-names>
</name>
, <name><surname>Burke</surname>
<given-names>GL</given-names>
</name>
, <etal>et al</etal>
(<year>2008</year>
) <article-title>Modifications to the Healthy Eating Index and its ability to predict obesity: the Multi-Ethnic Study of Atherosclerosis</article-title>
. <source>American Journal of Clinical Nutrition</source>
<volume>88</volume>
: <fpage>64</fpage>
–<lpage>69</lpage>
<pub-id pub-id-type="pmid">18614725</pub-id>
</mixed-citation>
</ref>
<ref id="pone.0087083-Arabshahi1"><label>13</label>
<mixed-citation publication-type="journal"><name><surname>Arabshahi</surname>
<given-names>S</given-names>
</name>
, <name><surname>van der Pols</surname>
<given-names>JC</given-names>
</name>
, <name><surname>Williams</surname>
<given-names>GM</given-names>
</name>
, <name><surname>Marks</surname>
<given-names>GC</given-names>
</name>
, <name><surname>Lahmann</surname>
<given-names>PH</given-names>
</name>
(<year>2012</year>
) <article-title>Diet quality and change in anthropometric measures: 15-year longitudinal study in Australian adults</article-title>
. <source>Br J Nutr</source>
<volume>107</volume>
: <fpage>1376</fpage>
–<lpage>1385</lpage>
</mixed-citation>
</ref>
<ref id="pone.0087083-Kimokoti1"><label>14</label>
<mixed-citation publication-type="journal"><name><surname>Kimokoti</surname>
<given-names>RW</given-names>
</name>
, <name><surname>Newby</surname>
<given-names>PK</given-names>
</name>
, <name><surname>Gona</surname>
<given-names>P</given-names>
</name>
, <name><surname>Zhu</surname>
<given-names>L</given-names>
</name>
, <name><surname>Jasuja</surname>
<given-names>GK</given-names>
</name>
, <etal>et al</etal>
(<year>2010</year>
) <article-title>Diet Quality, Physical Activity, Smoking Status, and Weight Fluctuation Are Associated with Weight Change in Women and Men</article-title>
. <source>Journal of Nutrition</source>
<volume>140</volume>
: <fpage>1287</fpage>
–<lpage>1293</lpage>
<pub-id pub-id-type="pmid">20484553</pub-id>
</mixed-citation>
</ref>
<ref id="pone.0087083-Quatromoni1"><label>15</label>
<mixed-citation publication-type="journal"><name><surname>Quatromoni</surname>
<given-names>PA</given-names>
</name>
, <name><surname>Pencina</surname>
<given-names>M</given-names>
</name>
, <name><surname>Cobain</surname>
<given-names>MR</given-names>
</name>
, <name><surname>Jacques</surname>
<given-names>PF</given-names>
</name>
, <name><surname>D'Agostino</surname>
<given-names>RB</given-names>
</name>
(<year>2006</year>
) <article-title>Dietary quality predicts adult weight gain: Findings from the Framingham Offspring Study</article-title>
. <source>Obesity</source>
<volume>14</volume>
: <fpage>1383</fpage>
–<lpage>1391</lpage>
<pub-id pub-id-type="pmid">16988081</pub-id>
</mixed-citation>
</ref>
<ref id="pone.0087083-Zamora1"><label>16</label>
<mixed-citation publication-type="journal"><name><surname>Zamora</surname>
<given-names>D</given-names>
</name>
, <name><surname>Gordon-Larsen</surname>
<given-names>P</given-names>
</name>
, <name><surname>Jacobs</surname>
<given-names>DR</given-names>
</name>
, <name><surname>Popkin</surname>
<given-names>BM</given-names>
</name>
(<year>2010</year>
) <article-title>Diet quality and weight gain among black and white young adults: the Coronary Artery Risk Development in Young Adults (CARDIA) Study (1985–2005)</article-title>
. <source>American Journal of Clinical Nutrition</source>
<volume>92</volume>
: <fpage>784</fpage>
–<lpage>793</lpage>
<pub-id pub-id-type="pmid">20685947</pub-id>
</mixed-citation>
</ref>
<ref id="pone.0087083-Wolongevicz1"><label>17</label>
<mixed-citation publication-type="other">Wolongevicz DM, Zhu L, Pencina MJ, Kimokoti RW, Newby PK, <etal>et al</etal>
. (2010) An obesity dietary quality index predicts abdominal obesity in women: potential opportunity for new prevention and treatment paradigms. Journal of Obesity 2010: Article ID 945987, 9 pages.</mixed-citation>
</ref>
<ref id="pone.0087083-Wolongevicz2"><label>18</label>
<mixed-citation publication-type="journal"><name><surname>Wolongevicz</surname>
<given-names>DM</given-names>
</name>
, <name><surname>Zhu</surname>
<given-names>L</given-names>
</name>
, <name><surname>Pencina</surname>
<given-names>MJ</given-names>
</name>
, <name><surname>Kimokoti</surname>
<given-names>RW</given-names>
</name>
, <name><surname>Newby</surname>
<given-names>PK</given-names>
</name>
, <etal>et al</etal>
(<year>2010</year>
) <article-title>Diet quality and obesity in women: the Framingham Nutrition Studies</article-title>
. <source>British Journal of Nutrition</source>
<volume>103</volume>
: <fpage>1223</fpage>
–<lpage>1229</lpage>
<pub-id pub-id-type="pmid">19930766</pub-id>
</mixed-citation>
</ref>
<ref id="pone.0087083-Lassale1"><label>19</label>
<mixed-citation publication-type="journal"><name><surname>Lassale</surname>
<given-names>C</given-names>
</name>
, <name><surname>Fezeu</surname>
<given-names>L</given-names>
</name>
, <name><surname>Andreeva</surname>
<given-names>VA</given-names>
</name>
, <name><surname>Hercberg</surname>
<given-names>S</given-names>
</name>
, <name><surname>Kengne</surname>
<given-names>AP</given-names>
</name>
, <etal>et al</etal>
(<year>2012</year>
) <article-title>Association between dietary scores and 13-year weight change and obesity risk in a French prospective cohort</article-title>
. <source>Int J Obes (Lond)</source>
<volume>36</volume>
: <fpage>1455</fpage>
–<lpage>1462</lpage>
<pub-id pub-id-type="pmid">22249228</pub-id>
</mixed-citation>
</ref>
<ref id="pone.0087083-KesseGuyot1"><label>20</label>
<mixed-citation publication-type="journal"><name><surname>Kesse-Guyot</surname>
<given-names>E</given-names>
</name>
, <name><surname>Castetbon</surname>
<given-names>K</given-names>
</name>
, <name><surname>Estaquio</surname>
<given-names>C</given-names>
</name>
, <name><surname>Czernichow</surname>
<given-names>S</given-names>
</name>
, <name><surname>Galan</surname>
<given-names>P</given-names>
</name>
, <etal>et al</etal>
(<year>2009</year>
) <article-title>Association Between the French Nutritional Guideline-based Score and 6-Year Anthropometric Changes in a French Middle-aged Adult Cohort</article-title>
. <source>American Journal of Epidemiology</source>
<volume>170</volume>
: <fpage>757</fpage>
–<lpage>765</lpage>
<pub-id pub-id-type="pmid">19656810</pub-id>
</mixed-citation>
</ref>
<ref id="pone.0087083-Hercberg2"><label>21</label>
<mixed-citation publication-type="journal"><name><surname>Hercberg</surname>
<given-names>S</given-names>
</name>
, <name><surname>Galan</surname>
<given-names>P</given-names>
</name>
, <name><surname>Preziosi</surname>
<given-names>P</given-names>
</name>
, <name><surname>Bertrais</surname>
<given-names>S</given-names>
</name>
, <name><surname>Mennen</surname>
<given-names>L</given-names>
</name>
, <etal>et al</etal>
(<year>2004</year>
) <article-title>The SU.VI.MAX study – A randomized, placebo-controlled trial of the health effects of antioxidant vitamins and minerals</article-title>
. <source>Archives of Internal Medicine</source>
<volume>164</volume>
: <fpage>2335</fpage>
–<lpage>2342</lpage>
<pub-id pub-id-type="pmid">15557412</pub-id>
</mixed-citation>
</ref>
<ref id="pone.0087083-LeMoullec1"><label>22</label>
<mixed-citation publication-type="journal"><name><surname>Le Moullec</surname>
<given-names>N</given-names>
</name>
, <name><surname>Deheeger</surname>
<given-names>M</given-names>
</name>
, <name><surname>Preziosi</surname>
<given-names>P</given-names>
</name>
, <name><surname>Monteiro</surname>
<given-names>P</given-names>
</name>
, <name><surname>Valeix</surname>
<given-names>P</given-names>
</name>
, <etal>et al</etal>
(<year>1996</year>
) <article-title>Validation of the photo manual used for the collection of dietary data in the SU.VI.MAX study</article-title>
. <source>Cah Nutr Diét</source>
<volume>31</volume>
: <fpage>158</fpage>
–<lpage>164</lpage>
</mixed-citation>
</ref>
<ref id="pone.0087083-Hercberg3"><label>23</label>
<mixed-citation publication-type="other">Hercberg S (2005) Table de composition SU.VI.MAX des aliments. Les éditions INSERM/Economica, Paris: 182.</mixed-citation>
</ref>
<ref id="pone.0087083-Mennen1"><label>24</label>
<mixed-citation publication-type="journal"><name><surname>Mennen</surname>
<given-names>LI</given-names>
</name>
, <name><surname>Bertrais</surname>
<given-names>S</given-names>
</name>
, <name><surname>Galan</surname>
<given-names>P</given-names>
</name>
, <name><surname>Arnault</surname>
<given-names>N</given-names>
</name>
, <name><surname>de Couray</surname>
<given-names>GP</given-names>
</name>
, <etal>et al</etal>
(<year>2002</year>
) <article-title>The use of computerised 24 h dietary recalls in the French SU.VI.MAX Study: number of recalls required</article-title>
. <source>European Journal of Clinical Nutrition</source>
<volume>56</volume>
: <fpage>659</fpage>
–<lpage>665</lpage>
<pub-id pub-id-type="pmid">12080407</pub-id>
</mixed-citation>
</ref>
<ref id="pone.0087083-Lasfargues1"><label>25</label>
<mixed-citation publication-type="journal"><name><surname>Lasfargues</surname>
<given-names>G</given-names>
</name>
, <name><surname>Vol</surname>
<given-names>S</given-names>
</name>
, <name><surname>Leclesiau</surname>
<given-names>H</given-names>
</name>
, <name><surname>Bedouet</surname>
<given-names>M</given-names>
</name>
, <name><surname>Hagel</surname>
<given-names>L</given-names>
</name>
, <etal>et al</etal>
(<year>1990</year>
) <article-title>Validity of a short self-administered dietary questionnaire compared with a dietetic interview</article-title>
. <source>Presse Medicale</source>
<volume>19</volume>
: <fpage>953</fpage>
–<lpage>957</lpage>
</mixed-citation>
</ref>
<ref id="pone.0087083-Vuillemin1"><label>26</label>
<mixed-citation publication-type="journal"><name><surname>Vuillemin</surname>
<given-names>A</given-names>
</name>
, <name><surname>Oppert</surname>
<given-names>JM</given-names>
</name>
, <name><surname>Guillemin</surname>
<given-names>F</given-names>
</name>
, <name><surname>Essermeant</surname>
<given-names>L</given-names>
</name>
, <name><surname>Fontvieille</surname>
<given-names>AM</given-names>
</name>
, <etal>et al</etal>
(<year>2000</year>
) <article-title>Self-administered questionnaire compared with interview to assess past-year physical activity</article-title>
. <source>Medicine and Science in Sports and Exercise</source>
<volume>32</volume>
: <fpage>1119</fpage>
–<lpage>1124</lpage>
<pub-id pub-id-type="pmid">10862539</pub-id>
</mixed-citation>
</ref>
<ref id="pone.0087083-Schulz1"><label>27</label>
<mixed-citation publication-type="journal"><name><surname>Schulz</surname>
<given-names>LO</given-names>
</name>
, <name><surname>Harper</surname>
<given-names>IT</given-names>
</name>
, <name><surname>Smith</surname>
<given-names>CJ</given-names>
</name>
, <name><surname>Kriska</surname>
<given-names>AM</given-names>
</name>
, <name><surname>Ravussin</surname>
<given-names>E</given-names>
</name>
(<year>1994</year>
) <article-title>Energy intake and physical activity in Pima Indians: comparison with energy expenditure measured by doubly-labeled water</article-title>
. <source>Obes Res</source>
<volume>2</volume>
: <fpage>541</fpage>
–<lpage>548</lpage>
<pub-id pub-id-type="pmid">16355515</pub-id>
</mixed-citation>
</ref>
<ref id="pone.0087083-Kriska1"><label>28</label>
<mixed-citation publication-type="journal"><name><surname>Kriska</surname>
<given-names>AM</given-names>
</name>
, <name><surname>Knowler</surname>
<given-names>WC</given-names>
</name>
, <name><surname>LaPorte</surname>
<given-names>RE</given-names>
</name>
, <name><surname>Drash</surname>
<given-names>AL</given-names>
</name>
, <name><surname>Wing</surname>
<given-names>RR</given-names>
</name>
, <etal>et al</etal>
(<year>1990</year>
) <article-title>Development of questionnaire to examine relationship of physical activity and diabetes in Pima Indians</article-title>
. <source>Diabetes Care</source>
<volume>13</volume>
: <fpage>401</fpage>
–<lpage>411</lpage>
<pub-id pub-id-type="pmid">2318100</pub-id>
</mixed-citation>
</ref>
<ref id="pone.0087083-Ainsworth1"><label>29</label>
<mixed-citation publication-type="journal"><name><surname>Ainsworth</surname>
<given-names>BE</given-names>
</name>
, <name><surname>Haskell</surname>
<given-names>WL</given-names>
</name>
, <name><surname>Whitt</surname>
<given-names>MC</given-names>
</name>
, <name><surname>Irwin</surname>
<given-names>ML</given-names>
</name>
, <name><surname>Swartz</surname>
<given-names>AM</given-names>
</name>
, <etal>et al</etal>
(<year>2000</year>
) <article-title>Compendium of Physical Activities: an update of activity codes and MET intensities</article-title>
. <source>Medicine and Science in Sports and Exercise</source>
<volume>32</volume>
: <fpage>S498</fpage>
–<lpage>S516</lpage>
<pub-id pub-id-type="pmid">10993420</pub-id>
</mixed-citation>
</ref>
<ref id="pone.0087083-Ainsworth2"><label>30</label>
<mixed-citation publication-type="journal"><name><surname>Ainsworth</surname>
<given-names>BE</given-names>
</name>
, <name><surname>Haskell</surname>
<given-names>WL</given-names>
</name>
, <name><surname>Leon</surname>
<given-names>AS</given-names>
</name>
, <name><surname>Jacobs</surname>
<given-names>DR</given-names>
</name>
, <name><surname>Montoye</surname>
<given-names>HJ</given-names>
</name>
, <etal>et al</etal>
(<year>1993</year>
) <article-title>Compendium of physical activities – classification of energy costs of human physical activities</article-title>
. <source>Medicine and Science in Sports and Exercise</source>
<volume>25</volume>
: <fpage>71</fpage>
–<lpage>80</lpage>
<pub-id pub-id-type="pmid">8292105</pub-id>
</mixed-citation>
</ref>
<ref id="pone.0087083-Lairon1"><label>31</label>
<mixed-citation publication-type="journal"><name><surname>Lairon</surname>
<given-names>D</given-names>
</name>
, <name><surname>Arnault</surname>
<given-names>N</given-names>
</name>
, <name><surname>Bertrais</surname>
<given-names>S</given-names>
</name>
, <name><surname>Planells</surname>
<given-names>R</given-names>
</name>
, <name><surname>Clero</surname>
<given-names>E</given-names>
</name>
, <etal>et al</etal>
(<year>2005</year>
) <article-title>Dietary fiber intake and risk factors for cardiovascular disease in French adults</article-title>
. <source>American Journal of Clinical Nutrition</source>
<volume>82</volume>
: <fpage>1185</fpage>
–<lpage>1194</lpage>
<pub-id pub-id-type="pmid">16332650</pub-id>
</mixed-citation>
</ref>
<ref id="pone.0087083-Estaquio1"><label>32</label>
<mixed-citation publication-type="journal"><name><surname>Estaquio</surname>
<given-names>C</given-names>
</name>
, <name><surname>Kesse-Guyot</surname>
<given-names>E</given-names>
</name>
, <name><surname>Deschamps</surname>
<given-names>V</given-names>
</name>
, <name><surname>Bertrais</surname>
<given-names>S</given-names>
</name>
, <name><surname>Dauchet</surname>
<given-names>L</given-names>
</name>
, <etal>et al</etal>
(<year>2009</year>
) <article-title>Adherence to the French Programme National Nutrition Sante Guideline Score Is Associated with Better Nutrient Intake and Nutritional Status</article-title>
. <source>Journal of the American Dietetic Association</source>
<volume>109</volume>
: <fpage>1031</fpage>
–<lpage>1041</lpage>
<pub-id pub-id-type="pmid">19465185</pub-id>
</mixed-citation>
</ref>
<ref id="pone.0087083-Schofield1"><label>33</label>
<mixed-citation publication-type="journal"><name><surname>Schofield</surname>
<given-names>WN</given-names>
</name>
(<year>1985</year>
) <article-title>Predicting basal metabolic rate, new standards and review of previous work</article-title>
. <source>Hum Nutr Clin Nutr</source>
<volume>39</volume>
Suppl 1<fpage>5</fpage>
–<lpage>41</lpage>
<pub-id pub-id-type="pmid">4044297</pub-id>
</mixed-citation>
</ref>
<ref id="pone.0087083-Dunnett1"><label>34</label>
<mixed-citation publication-type="journal"><name><surname>Dunnett</surname>
<given-names>CW</given-names>
</name>
(<year>1955</year>
) <article-title>A Multiple Comparisons Procedure for Comparing Several Treatments with a Control</article-title>
. <source>Journal of the American Statistical Association</source>
<volume>272</volume>
: <fpage>1096</fpage>
–<lpage>1121</lpage>
</mixed-citation>
</ref>
<ref id="pone.0087083-Newby1"><label>35</label>
<mixed-citation publication-type="journal"><name><surname>Newby</surname>
<given-names>PK</given-names>
</name>
, <name><surname>Weismayer</surname>
<given-names>C</given-names>
</name>
, <name><surname>Akesson</surname>
<given-names>A</given-names>
</name>
, <name><surname>Tucker</surname>
<given-names>KL</given-names>
</name>
, <name><surname>Wolk</surname>
<given-names>A</given-names>
</name>
(<year>2006</year>
) <article-title>Longitudinal changes in food patterns predict changes in weight and body mass index and the effects are greatest in obese women</article-title>
. <source>Journal of Nutrition</source>
<volume>136</volume>
: <fpage>2580</fpage>
–<lpage>2587</lpage>
<pub-id pub-id-type="pmid">16988130</pub-id>
</mixed-citation>
</ref>
<ref id="pone.0087083-Nakade1"><label>36</label>
<mixed-citation publication-type="journal"><name><surname>Nakade</surname>
<given-names>M</given-names>
</name>
, <name><surname>Lee</surname>
<given-names>JS</given-names>
</name>
, <name><surname>Kawakubo</surname>
<given-names>K</given-names>
</name>
, <name><surname>Kondo</surname>
<given-names>K</given-names>
</name>
, <name><surname>Mori</surname>
<given-names>K</given-names>
</name>
, <etal>et al</etal>
(<year>2009</year>
) <article-title>Changes in food intake patterns associated with body weight loss during a 12-week health promotion program and a 9-month follow-up period in a Japanese population</article-title>
. <source>Obesity Research & Clinical Practice</source>
<volume>3</volume>
: <fpage>85</fpage>
–<lpage>98</lpage>
</mixed-citation>
</ref>
<ref id="pone.0087083-Newby2"><label>37</label>
<mixed-citation publication-type="journal"><name><surname>Newby</surname>
<given-names>PK</given-names>
</name>
, <name><surname>Muller</surname>
<given-names>D</given-names>
</name>
, <name><surname>Hallfrisch</surname>
<given-names>J</given-names>
</name>
, <name><surname>Andres</surname>
<given-names>R</given-names>
</name>
, <name><surname>Tucker</surname>
<given-names>KL</given-names>
</name>
(<year>2004</year>
) <article-title>Food patterns measured by factor analysis and anthropometric changes in adults</article-title>
. <source>American Journal of Clinical Nutrition</source>
<volume>80</volume>
: <fpage>504</fpage>
–<lpage>513</lpage>
<pub-id pub-id-type="pmid">15277177</pub-id>
</mixed-citation>
</ref>
<ref id="pone.0087083-Schulze1"><label>38</label>
<mixed-citation publication-type="journal"><name><surname>Schulze</surname>
<given-names>MB</given-names>
</name>
, <name><surname>Fung</surname>
<given-names>TT</given-names>
</name>
, <name><surname>Manson</surname>
<given-names>JE</given-names>
</name>
, <name><surname>Willett</surname>
<given-names>WC</given-names>
</name>
, <name><surname>Hu</surname>
<given-names>FB</given-names>
</name>
(<year>2006</year>
) <article-title>Dietary patterns and changes in body weight in women</article-title>
. <source>Obesity</source>
<volume>14</volume>
: <fpage>1444</fpage>
–<lpage>1453</lpage>
<pub-id pub-id-type="pmid">16988088</pub-id>
</mixed-citation>
</ref>
<ref id="pone.0087083-Newby3"><label>39</label>
<mixed-citation publication-type="journal"><name><surname>Newby</surname>
<given-names>P</given-names>
</name>
, <name><surname>Muller</surname>
<given-names>D</given-names>
</name>
, <name><surname>Hallfrisch</surname>
<given-names>J</given-names>
</name>
, <name><surname>Qiao</surname>
<given-names>N</given-names>
</name>
, <name><surname>Andres</surname>
<given-names>R</given-names>
</name>
, <etal>et al</etal>
(<year>2003</year>
) <article-title>Dietary patterns and changes in body mass index and waist circumference in adults</article-title>
. <source>American Journal of Clinical Nutrition</source>
<volume>77</volume>
: <fpage>1417</fpage>
–<lpage>1425</lpage>
<pub-id pub-id-type="pmid">12791618</pub-id>
</mixed-citation>
</ref>
<ref id="pone.0087083-Black1"><label>40</label>
<mixed-citation publication-type="journal"><name><surname>Black</surname>
<given-names>AE</given-names>
</name>
(<year>2000</year>
) <article-title>Critical evaluation of energy intake using the Goldberg cut-off for energy intake:basal metabolic rate. A practical guide to its calculation, use and limitations</article-title>
. <source>Int J Obes Relat Metab Disord</source>
<volume>24</volume>
: <fpage>1119</fpage>
–<lpage>1130</lpage>
<pub-id pub-id-type="pmid">11033980</pub-id>
</mixed-citation>
</ref>
<ref id="pone.0087083-FAOWHOUNU1"><label>41</label>
<mixed-citation publication-type="other">FAO/WHO/UNU (2004) Human energy requirements: Report of a Joint FAO/WHO/UNU Expert Consultation, 17–24 October 2001, Rome, Italy. FAO Food and Nutrition Technical Report Series 1. Rome 2004.</mixed-citation>
</ref>
<ref id="pone.0087083-Timperio1"><label>42</label>
<mixed-citation publication-type="journal"><name><surname>Timperio</surname>
<given-names>A</given-names>
</name>
, <name><surname>Cameron-Smith</surname>
<given-names>D</given-names>
</name>
, <name><surname>Burns</surname>
<given-names>C</given-names>
</name>
, <name><surname>Crawford</surname>
<given-names>D</given-names>
</name>
(<year>2000</year>
) <article-title>The public's response to the obesity epidemic in Australia: weight concerns and weight control practices of men and women</article-title>
. <source>Public Health Nutr</source>
<volume>3</volume>
: <fpage>417</fpage>
–<lpage>424</lpage>
<pub-id pub-id-type="pmid">11135796</pub-id>
</mixed-citation>
</ref>
<ref id="pone.0087083-Ulijaszek1"><label>43</label>
<mixed-citation publication-type="journal"><name><surname>Ulijaszek</surname>
<given-names>SJ</given-names>
</name>
, <name><surname>Kerr</surname>
<given-names>DA</given-names>
</name>
(<year>1999</year>
) <article-title>Anthropometric measurement error and the assessment of nutritional status</article-title>
. <source>British Journal of Nutrition</source>
<volume>82</volume>
: <fpage>165</fpage>
–<lpage>177</lpage>
<pub-id pub-id-type="pmid">10655963</pub-id>
</mixed-citation>
</ref>
<ref id="pone.0087083-Nordhamn1"><label>44</label>
<mixed-citation publication-type="journal"><name><surname>Nordhamn</surname>
<given-names>K</given-names>
</name>
, <name><surname>Sodergren</surname>
<given-names>E</given-names>
</name>
, <name><surname>Olsson</surname>
<given-names>E</given-names>
</name>
, <name><surname>Karlstrom</surname>
<given-names>B</given-names>
</name>
, <name><surname>Vessby</surname>
<given-names>B</given-names>
</name>
, <etal>et al</etal>
(<year>2000</year>
) <article-title>Reliability of anthropometric measurements in overweight and lean subjects: consequences for correlations between anthropometric and other variables</article-title>
. <source>International Journal of Obesity</source>
<volume>24</volume>
: <fpage>652</fpage>
–<lpage>657</lpage>
<pub-id pub-id-type="pmid">10849590</pub-id>
</mixed-citation>
</ref>
<ref id="pone.0087083-Resnick1"><label>45</label>
<mixed-citation publication-type="journal"><name><surname>Resnick</surname>
<given-names>HE</given-names>
</name>
, <name><surname>Valsania</surname>
<given-names>P</given-names>
</name>
, <name><surname>Halter</surname>
<given-names>JB</given-names>
</name>
, <name><surname>Lin</surname>
<given-names>X</given-names>
</name>
(<year>2000</year>
) <article-title>Relation of weight gain and weight loss on subsequent diabetes risk in overweight adults</article-title>
. <source>J Epidemiol Community Health</source>
<volume>54</volume>
: <fpage>596</fpage>
–<lpage>602</lpage>
<pub-id pub-id-type="pmid">10890871</pub-id>
</mixed-citation>
</ref>
<ref id="pone.0087083-Czernichow1"><label>46</label>
<mixed-citation publication-type="journal"><name><surname>Czernichow</surname>
<given-names>S</given-names>
</name>
, <name><surname>Mennen</surname>
<given-names>L</given-names>
</name>
, <name><surname>Bertrais</surname>
<given-names>S</given-names>
</name>
, <name><surname>Preziosi</surname>
<given-names>P</given-names>
</name>
, <name><surname>Hercberg</surname>
<given-names>S</given-names>
</name>
, <etal>et al</etal>
(<year>2002</year>
) <article-title>Relationships between changes in weight and changes in cardiovascular risk factors in middle-aged French subjects: effect of dieting</article-title>
. <source>Int J Obes Relat Metab Disord</source>
<volume>26</volume>
: <fpage>1138</fpage>
–<lpage>1143</lpage>
<pub-id pub-id-type="pmid">12119581</pub-id>
</mixed-citation>
</ref>
<ref id="pone.0087083-Seaman1"><label>47</label>
<mixed-citation publication-type="journal"><name><surname>Seaman</surname>
<given-names>SR</given-names>
</name>
, <name><surname>White</surname>
<given-names>IR</given-names>
</name>
(<year>2011</year>
) <article-title>Review of inverse probability weighting for dealing with missing data</article-title>
. <source>Stat Methods Med Res</source>
<volume>22</volume>
: <fpage>278</fpage>
–<lpage>295</lpage>
<pub-id pub-id-type="pmid">21220355</pub-id>
</mixed-citation>
</ref>
<ref id="pone.0087083-Shen1"><label>48</label>
<mixed-citation publication-type="journal"><name><surname>Shen</surname>
<given-names>C</given-names>
</name>
, <name><surname>Li</surname>
<given-names>X</given-names>
</name>
, <name><surname>Li</surname>
<given-names>L</given-names>
</name>
, <name><surname>Were</surname>
<given-names>MC</given-names>
</name>
(<year>2011</year>
) <article-title>Sensitivity analysis for causal inference using inverse probability weighting</article-title>
. <source>Biom J</source>
<volume>53</volume>
: <fpage>822</fpage>
–<lpage>837</lpage>
<pub-id pub-id-type="pmid">21770046</pub-id>
</mixed-citation>
</ref>
<ref id="pone.0087083-Hofler1"><label>49</label>
<mixed-citation publication-type="journal"><name><surname>Hofler</surname>
<given-names>M</given-names>
</name>
, <name><surname>Pfister</surname>
<given-names>H</given-names>
</name>
, <name><surname>Lieb</surname>
<given-names>R</given-names>
</name>
, <name><surname>Wittchen</surname>
<given-names>HU</given-names>
</name>
(<year>2005</year>
) <article-title>The use of weights to account for non-response and drop-out</article-title>
. <source>Social Psychiatry and Psychiatric Epidemiology</source>
<volume>40</volume>
: <fpage>291</fpage>
–<lpage>299</lpage>
<pub-id pub-id-type="pmid">15834780</pub-id>
</mixed-citation>
</ref>
<ref id="pone.0087083-InsermTNS1"><label>50</label>
<mixed-citation publication-type="other">Inserm-TNS Healthcare-Roche (2009) ObEpi Roche 2009– Enquête épidémiologique nationale sur le surpoids et l'obésité. Available at <ext-link ext-link-type="uri" xlink:href="http://www.roche.fr/content/dam/corporate/roche_fr/doc/AttachedFile_10160.pdf">http://www.roche.fr/content/dam/corporate/roche_fr/doc/AttachedFile_10160.pdf</ext-link>
</mixed-citation>
</ref>
<ref id="pone.0087083-ConnorGorber1"><label>51</label>
<mixed-citation publication-type="journal"><name><surname>Connor Gorber</surname>
<given-names>S</given-names>
</name>
, <name><surname>Tremblay</surname>
<given-names>M</given-names>
</name>
, <name><surname>Moher</surname>
<given-names>D</given-names>
</name>
, <name><surname>Gorber</surname>
<given-names>B</given-names>
</name>
(<year>2007</year>
) <article-title>A comparison of direct vs. self-report measures for assessing height, weight and body mass index: a systematic review</article-title>
. <source>Obesity reviews: an official journal of the International Association for the Study of Obesity</source>
<volume>8</volume>
: <fpage>307</fpage>
–<lpage>326</lpage>
<pub-id pub-id-type="pmid">17578381</pub-id>
</mixed-citation>
</ref>
<ref id="pone.0087083-Ma1"><label>52</label>
<mixed-citation publication-type="journal"><name><surname>Ma</surname>
<given-names>Y</given-names>
</name>
, <name><surname>Olendzki</surname>
<given-names>BC</given-names>
</name>
, <name><surname>Pagoto</surname>
<given-names>SL</given-names>
</name>
, <name><surname>Hurley</surname>
<given-names>TG</given-names>
</name>
, <name><surname>Magner</surname>
<given-names>RP</given-names>
</name>
, <etal>et al</etal>
(<year>2009</year>
) <article-title>Number of 24-Hour Diet Recalls Needed to Estimate Energy Intake</article-title>
. <source>Annals of Epidemiology</source>
<volume>19</volume>
: <fpage>553</fpage>
–<lpage>559</lpage>
<pub-id pub-id-type="pmid">19576535</pub-id>
</mixed-citation>
</ref>
<ref id="pone.0087083-Alberti1"><label>53</label>
<mixed-citation publication-type="journal"><name><surname>Alberti</surname>
<given-names>KG</given-names>
</name>
, <name><surname>Eckel</surname>
<given-names>RH</given-names>
</name>
, <name><surname>Grundy</surname>
<given-names>SM</given-names>
</name>
, <name><surname>Zimmet</surname>
<given-names>PZ</given-names>
</name>
, <name><surname>Cleeman</surname>
<given-names>JI</given-names>
</name>
, <etal>et al</etal>
(<year>2009</year>
) <article-title>Harmonizing the metabolic syndrome: a joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity</article-title>
. <source>Circulation</source>
<volume>120</volume>
: <fpage>1640</fpage>
–<lpage>1645</lpage>
<pub-id pub-id-type="pmid">19805654</pub-id>
</mixed-citation>
</ref>
</ref-list>
</back>
</pmc>
</record>
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