Heart rate variability and target organ damage in hypertensive patients
Identifieur interne : 000569 ( Main/Exploration ); précédent : 000568; suivant : 000570Heart rate variability and target organ damage in hypertensive patients
Auteurs : Paolo Melillo [Italie] ; Raffaele Izzo [Italie] ; Nicola De Luca [Italie] ; Leandro Pecchia [Royaume-Uni]Source :
- BMC Cardiovascular Disorders [ 1471-2261 ] ; 2012.
Abstract
We evaluated the association between linear standard Heart Rate Variability (HRV) measures and vascular, renal and cardiac target organ damage (TOD).
A retrospective analysis was performed including 200 patients registered in the Regione Campania network (aged 62.4 ± 12, male 64%). HRV analysis was performed by 24-h holter ECG. Renal damage was assessed by estimated glomerular filtration rate (eGFR), vascular damage by carotid intima-media thickness (IMT), and cardiac damage by left ventricular mass index.
Significantly lower values of the ratio of low to high frequency power (LF/HF) were found in the patients with moderate or severe eGFR (p-value < 0.001). Similarly, depressed values of indexes of the overall autonomic modulation on heart were found in patients with plaque compared to those with a normal IMT (p-value <0.05). These associations remained significant after adjustment for other factors known to contribute to the development of target organ damage, such as age. Moreover, depressed LF/HF was found also in patients with left ventricular hypertrophy but this association was not significant after adjustment for other factors.
Depressed HRV appeared to be associated with vascular and renal TOD, suggesting the involvement of autonomic imbalance in the TOD. However, as the mechanisms by which abnormal autonomic balance may lead to TOD, and, particularly, to renal organ damage are not clearly known, further prospective studies with longitudinal design are needed to determine the association between HRV and the development of TOD.
Url:
DOI: 10.1186/1471-2261-12-105
PubMed: 23153340
PubMed Central: 3536621
Affiliations:
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Heart rate variability and target organ damage in hypertensive patients</title><author><name sortKey="Melillo, Paolo" sort="Melillo, Paolo" uniqKey="Melillo P" first="Paolo" last="Melillo">Paolo Melillo</name><affiliation wicri:level="1"><nlm:aff id="I1">Multidisciplinary Department of Medical Sciences, Second University of Naples, Via Pansini, 5, Naples, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Multidisciplinary Department of Medical Sciences, Second University of Naples, Via Pansini, 5, Naples</wicri:regionArea><wicri:noRegion>Naples</wicri:noRegion></affiliation></author><author><name sortKey="Izzo, Raffaele" sort="Izzo, Raffaele" uniqKey="Izzo R" first="Raffaele" last="Izzo">Raffaele Izzo</name><affiliation wicri:level="1"><nlm:aff id="I2">Departments of Clinical Medicine, Cardiovascular and Immunological Sciences, Federico II University Hospital, Via Pansini, 5, Naples, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Departments of Clinical Medicine, Cardiovascular and Immunological Sciences, Federico II University Hospital, Via Pansini, 5, Naples</wicri:regionArea><wicri:noRegion>Naples</wicri:noRegion></affiliation></author><author><name sortKey="De Luca, Nicola" sort="De Luca, Nicola" uniqKey="De Luca N" first="Nicola" last="De Luca">Nicola De Luca</name><affiliation wicri:level="1"><nlm:aff id="I2">Departments of Clinical Medicine, Cardiovascular and Immunological Sciences, Federico II University Hospital, Via Pansini, 5, Naples, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Departments of Clinical Medicine, Cardiovascular and Immunological Sciences, Federico II University Hospital, Via Pansini, 5, Naples</wicri:regionArea><wicri:noRegion>Naples</wicri:noRegion></affiliation></author><author><name sortKey="Pecchia, Leandro" sort="Pecchia, Leandro" uniqKey="Pecchia L" first="Leandro" last="Pecchia">Leandro Pecchia</name><affiliation wicri:level="4"><nlm:aff id="I3">Electrical Systems and optics research division, Faculty of Engineering, University of Nottingham, University Park, Nottingham, NG7 2RD, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Electrical Systems and optics research division, Faculty of Engineering, University of Nottingham, University Park, Nottingham, NG7 2RD</wicri:regionArea><orgName type="university">Université de Nottingham</orgName><placeName><settlement type="city">Nottingham</settlement><region type="nation">Angleterre</region><region type="région" nuts="1">Nottinghamshire</region></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">23153340</idno><idno type="pmc">3536621</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3536621</idno><idno type="RBID">PMC:3536621</idno><idno type="doi">10.1186/1471-2261-12-105</idno><date when="2012">2012</date><idno type="wicri:Area/Pmc/Corpus">000329</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000329</idno><idno type="wicri:Area/Pmc/Curation">000329</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000329</idno><idno type="wicri:Area/Pmc/Checkpoint">000301</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000301</idno><idno type="wicri:Area/Ncbi/Merge">000852</idno><idno type="wicri:Area/Ncbi/Curation">000852</idno><idno type="wicri:Area/Ncbi/Checkpoint">000852</idno><idno type="wicri:Area/Main/Merge">000569</idno><idno type="wicri:Area/Main/Curation">000569</idno><idno type="wicri:Area/Main/Exploration">000569</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Heart rate variability and target organ damage in hypertensive patients</title><author><name sortKey="Melillo, Paolo" sort="Melillo, Paolo" uniqKey="Melillo P" first="Paolo" last="Melillo">Paolo Melillo</name><affiliation wicri:level="1"><nlm:aff id="I1">Multidisciplinary Department of Medical Sciences, Second University of Naples, Via Pansini, 5, Naples, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Multidisciplinary Department of Medical Sciences, Second University of Naples, Via Pansini, 5, Naples</wicri:regionArea><wicri:noRegion>Naples</wicri:noRegion></affiliation></author><author><name sortKey="Izzo, Raffaele" sort="Izzo, Raffaele" uniqKey="Izzo R" first="Raffaele" last="Izzo">Raffaele Izzo</name><affiliation wicri:level="1"><nlm:aff id="I2">Departments of Clinical Medicine, Cardiovascular and Immunological Sciences, Federico II University Hospital, Via Pansini, 5, Naples, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Departments of Clinical Medicine, Cardiovascular and Immunological Sciences, Federico II University Hospital, Via Pansini, 5, Naples</wicri:regionArea><wicri:noRegion>Naples</wicri:noRegion></affiliation></author><author><name sortKey="De Luca, Nicola" sort="De Luca, Nicola" uniqKey="De Luca N" first="Nicola" last="De Luca">Nicola De Luca</name><affiliation wicri:level="1"><nlm:aff id="I2">Departments of Clinical Medicine, Cardiovascular and Immunological Sciences, Federico II University Hospital, Via Pansini, 5, Naples, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Departments of Clinical Medicine, Cardiovascular and Immunological Sciences, Federico II University Hospital, Via Pansini, 5, Naples</wicri:regionArea><wicri:noRegion>Naples</wicri:noRegion></affiliation></author><author><name sortKey="Pecchia, Leandro" sort="Pecchia, Leandro" uniqKey="Pecchia L" first="Leandro" last="Pecchia">Leandro Pecchia</name><affiliation wicri:level="4"><nlm:aff id="I3">Electrical Systems and optics research division, Faculty of Engineering, University of Nottingham, University Park, Nottingham, NG7 2RD, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Electrical Systems and optics research division, Faculty of Engineering, University of Nottingham, University Park, Nottingham, NG7 2RD</wicri:regionArea><orgName type="university">Université de Nottingham</orgName><placeName><settlement type="city">Nottingham</settlement><region type="nation">Angleterre</region><region type="région" nuts="1">Nottinghamshire</region></placeName></affiliation></author></analytic><series><title level="j">BMC Cardiovascular Disorders</title><idno type="eISSN">1471-2261</idno><imprint><date when="2012">2012</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec><title>Background</title><p>We evaluated the association between linear standard Heart Rate Variability (HRV) measures and vascular, renal and cardiac target organ damage (TOD).</p></sec><sec><title>Methods</title><p>A retrospective analysis was performed including 200 patients registered in the Regione Campania network (aged 62.4 ± 12, male 64%). HRV analysis was performed by 24-h holter ECG. Renal damage was assessed by estimated glomerular filtration rate (eGFR), vascular damage by carotid intima-media thickness (IMT), and cardiac damage by left ventricular mass index.</p></sec><sec><title>Results</title><p>Significantly lower values of the ratio of low to high frequency power (LF/HF) were found in the patients with moderate or severe eGFR (p-value < 0.001). Similarly, depressed values of indexes of the overall autonomic modulation on heart were found in patients with plaque compared to those with a normal IMT (p-value <0.05). These associations remained significant after adjustment for other factors known to contribute to the development of target organ damage, such as age. Moreover, depressed LF/HF was found also in patients with left ventricular hypertrophy but this association was not significant after adjustment for other factors.</p></sec><sec><title>Conclusions</title><p>Depressed HRV appeared to be associated with vascular and renal TOD, suggesting the involvement of autonomic imbalance in the TOD. However, as the mechanisms by which abnormal autonomic balance may lead to TOD, and, particularly, to renal organ damage are not clearly known, further prospective studies with longitudinal design are needed to determine the association between HRV and the development of TOD.</p></sec></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Yusuf, S" uniqKey="Yusuf S">S Yusuf</name></author><author><name sortKey="Reddy, S" uniqKey="Reddy S">S Reddy</name></author><author><name sortKey="Ounpuu, S" uniqKey="Ounpuu S">S Ounpuu</name></author><author><name sortKey="Anand, S" uniqKey="Anand S">S Anand</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chambless, Le" uniqKey="Chambless L">LE Chambless</name></author><author><name sortKey="Folsom, Ar" uniqKey="Folsom A">AR Folsom</name></author><author><name sortKey="Clegg, Lx" uniqKey="Clegg L">LX Clegg</name></author><author><name sortKey="Sharrett, Ar" uniqKey="Sharrett A">AR Sharrett</name></author><author><name sortKey="Shahar, E" uniqKey="Shahar E">E Shahar</name></author><author><name sortKey="Nieto, Fj" uniqKey="Nieto F">FJ Nieto</name></author><author><name sortKey="Rosamond, Wd" uniqKey="Rosamond W">WD Rosamond</name></author><author><name sortKey="Evans, G" uniqKey="Evans G">G Evans</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hollander, M" uniqKey="Hollander M">M Hollander</name></author><author><name sortKey="Bots, Ml" uniqKey="Bots M">ML Bots</name></author><author><name sortKey="Del Sol, Ai" uniqKey="Del Sol A">AI Del Sol</name></author><author><name sortKey="Koudstaal, Pj" uniqKey="Koudstaal P">PJ Koudstaal</name></author><author><name sortKey="Witteman, Jc" uniqKey="Witteman J">JC Witteman</name></author><author><name sortKey="Grobbee, De" uniqKey="Grobbee D">DE Grobbee</name></author><author><name sortKey="Hofman, A" uniqKey="Hofman A">A Hofman</name></author><author><name sortKey="Breteler, Mm" uniqKey="Breteler M">MM Breteler</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="O Leary, Dh" uniqKey="O Leary D">DH O'Leary</name></author><author><name sortKey="Polak, Jf" uniqKey="Polak J">JF Polak</name></author><author><name sortKey="Kronmal, Ra" uniqKey="Kronmal R">RA Kronmal</name></author><author><name sortKey="Manolio, Ta" uniqKey="Manolio T">TA Manolio</name></author><author><name sortKey="Burke, Gl" uniqKey="Burke G">GL Burke</name></author><author><name sortKey="Wolfson, Sk" uniqKey="Wolfson S">SK Wolfson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lorenz, Mw" uniqKey="Lorenz M">MW Lorenz</name></author><author><name sortKey="Von Kegler, S" uniqKey="Von Kegler S">S von Kegler</name></author><author><name sortKey="Steinmetz, H" uniqKey="Steinmetz H">H Steinmetz</name></author><author><name sortKey="Markus, Hs" uniqKey="Markus H">HS Markus</name></author><author><name sortKey="Sitzer, M" uniqKey="Sitzer M">M Sitzer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Devereux, Rb" uniqKey="Devereux R">RB Devereux</name></author><author><name sortKey="Alderman, Mh" uniqKey="Alderman M">MH Alderman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Thayer, Jf" uniqKey="Thayer J">JF Thayer</name></author><author><name sortKey="Yamamoto, Ss" uniqKey="Yamamoto S">SS Yamamoto</name></author><author><name sortKey="Brosschot, Jf" uniqKey="Brosschot J">JF Brosschot</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Malik, M" uniqKey="Malik M">M Malik</name></author><author><name sortKey="Bigger, Jt" uniqKey="Bigger J">JT Bigger</name></author><author><name sortKey="Camm, Aj" uniqKey="Camm A">AJ Camm</name></author><author><name sortKey="Kleiger, Re" uniqKey="Kleiger R">RE Kleiger</name></author><author><name sortKey="Malliani, A" uniqKey="Malliani A">A Malliani</name></author><author><name sortKey="Moss, Aj" uniqKey="Moss A">AJ Moss</name></author><author><name sortKey="Schwartz, Pj" uniqKey="Schwartz P">PJ Schwartz</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rajendra Acharya, U" uniqKey="Rajendra Acharya U">U Rajendra Acharya</name></author><author><name sortKey="Paul Joseph, K" uniqKey="Paul Joseph K">K Paul Joseph</name></author><author><name sortKey="Kannathal, N" uniqKey="Kannathal N">N Kannathal</name></author><author><name sortKey="Lim, Cm" uniqKey="Lim C">CM Lim</name></author><author><name sortKey="Suri, Js" uniqKey="Suri J">JS Suri</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Parati, G" uniqKey="Parati G">G Parati</name></author><author><name sortKey="Mancia, G" uniqKey="Mancia G">G Mancia</name></author><author><name sortKey="Di Rienzo, M" uniqKey="Di Rienzo M">M Di Rienzo</name></author><author><name sortKey="Castiglioni, P" uniqKey="Castiglioni P">P Castiglioni</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Arbolishvili, Gn" uniqKey="Arbolishvili G">GN Arbolishvili</name></author><author><name sortKey="Mareev, Vy" uniqKey="Mareev V">VY Mareev</name></author><author><name sortKey="Orlova, Ya" uniqKey="Orlova Y">YA Orlova</name></author><author><name sortKey="Belenkov, Yn" uniqKey="Belenkov Y">YN Belenkov</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Musialik Lydka, A" uniqKey="Musialik Lydka A">A Musialik-Lydka</name></author><author><name sortKey="Sredniawa, B" uniqKey="Sredniawa B">B Sredniawa</name></author><author><name sortKey="Pasyk, S" uniqKey="Pasyk S">S Pasyk</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Melillo, P" uniqKey="Melillo P">P Melillo</name></author><author><name sortKey="Fusco, R" uniqKey="Fusco R">R Fusco</name></author><author><name sortKey="Sansone, M" uniqKey="Sansone M">M Sansone</name></author><author><name sortKey="Bracale, M" uniqKey="Bracale M">M Bracale</name></author><author><name sortKey="Pecchia, L" uniqKey="Pecchia L">L Pecchia</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pecchia, L" uniqKey="Pecchia L">L Pecchia</name></author><author><name sortKey="Melillo, P" uniqKey="Melillo P">P Melillo</name></author><author><name sortKey="Sansone, M" uniqKey="Sansone M">M Sansone</name></author><author><name sortKey="Bracale, M" uniqKey="Bracale M">M Bracale</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ueno, Lm" uniqKey="Ueno L">LM Ueno</name></author><author><name sortKey="Drager, Lf" uniqKey="Drager L">LF Drager</name></author><author><name sortKey="Rodrigues, Ac" uniqKey="Rodrigues A">AC Rodrigues</name></author><author><name sortKey="Rondon, Mu" uniqKey="Rondon M">MU Rondon</name></author><author><name sortKey="Mathias, W" uniqKey="Mathias W">W Mathias</name></author><author><name sortKey="Krieger, Em" uniqKey="Krieger E">EM Krieger</name></author><author><name sortKey="Junior, Rf" uniqKey="Junior R">RF Junior</name></author><author><name sortKey="Negrao, Ce" uniqKey="Negrao C">CE Negrao</name></author><author><name sortKey="Lorenzi Filho, G" uniqKey="Lorenzi Filho G">G Lorenzi-Filho</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Alter, P" uniqKey="Alter P">P Alter</name></author><author><name sortKey="Rupp, H" uniqKey="Rupp H">H Rupp</name></author><author><name sortKey="Rominger, Mb" uniqKey="Rominger M">MB Rominger</name></author><author><name sortKey="Czerny, F" uniqKey="Czerny F">F Czerny</name></author><author><name sortKey="Vollrath, A" uniqKey="Vollrath A">A Vollrath</name></author><author><name sortKey="Klose, Kj" uniqKey="Klose K">KJ Klose</name></author><author><name sortKey="Maisch, B" uniqKey="Maisch B">B Maisch</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Vinik, Ai" uniqKey="Vinik A">AI Vinik</name></author><author><name sortKey="Ziegler, D" uniqKey="Ziegler D">D Ziegler</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Shehab, A" uniqKey="Shehab A">A Shehab</name></author><author><name sortKey="Abdulle, A" uniqKey="Abdulle A">A Abdulle</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Oikawa, K" uniqKey="Oikawa K">K Oikawa</name></author><author><name sortKey="Ishihara, R" uniqKey="Ishihara R">R Ishihara</name></author><author><name sortKey="Maeda, T" uniqKey="Maeda T">T Maeda</name></author><author><name sortKey="Yamaguchi, K" uniqKey="Yamaguchi K">K Yamaguchi</name></author><author><name sortKey="Koike, A" uniqKey="Koike A">A Koike</name></author><author><name sortKey="Kawaguchi, H" uniqKey="Kawaguchi H">H Kawaguchi</name></author><author><name sortKey="Tabata, Y" uniqKey="Tabata Y">Y Tabata</name></author><author><name sortKey="Murotani, N" uniqKey="Murotani N">N Murotani</name></author><author><name sortKey="Itoh, H" uniqKey="Itoh H">H Itoh</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chandra, P" uniqKey="Chandra P">P Chandra</name></author><author><name sortKey="Sands, Rl" uniqKey="Sands R">RL Sands</name></author><author><name sortKey="Gillespie, Bw" uniqKey="Gillespie B">BW Gillespie</name></author><author><name sortKey="Levin, Nw" uniqKey="Levin N">NW Levin</name></author><author><name sortKey="Kotanko, P" uniqKey="Kotanko P">P Kotanko</name></author><author><name sortKey="Kiser, M" uniqKey="Kiser M">M Kiser</name></author><author><name sortKey="Finkelstein, F" uniqKey="Finkelstein F">F Finkelstein</name></author><author><name sortKey="Hinderliter, A" uniqKey="Hinderliter A">A Hinderliter</name></author><author><name sortKey="Pop Busui, R" uniqKey="Pop Busui R">R Pop-Busui</name></author><author><name sortKey="Rajagopalan, S" uniqKey="Rajagopalan S">S Rajagopalan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Brotman, Dj" uniqKey="Brotman D">DJ Brotman</name></author><author><name sortKey="Bash, Ld" uniqKey="Bash L">LD Bash</name></author><author><name sortKey="Qayyum, R" uniqKey="Qayyum R">R Qayyum</name></author><author><name sortKey="Crews, D" uniqKey="Crews D">D Crews</name></author><author><name sortKey="Whitsel, Ea" uniqKey="Whitsel E">EA Whitsel</name></author><author><name sortKey="Astor, Bc" uniqKey="Astor B">BC Astor</name></author><author><name sortKey="Coresh, J" uniqKey="Coresh J">J Coresh</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Martini, G" uniqKey="Martini G">G Martini</name></author><author><name sortKey="Rabbia, F" uniqKey="Rabbia F">F Rabbia</name></author><author><name sortKey="Gastaldi, L" uniqKey="Gastaldi L">L Gastaldi</name></author><author><name sortKey="Riva, P" uniqKey="Riva P">P Riva</name></author><author><name sortKey="Sibona, Mp" uniqKey="Sibona M">MP Sibona</name></author><author><name sortKey="Morra Di Cella, S" uniqKey="Morra Di Cella S">S Morra Di Cella</name></author><author><name sortKey="Chiandussi, L" uniqKey="Chiandussi L">L Chiandussi</name></author><author><name sortKey="Veglio, F" uniqKey="Veglio F">F Veglio</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Garcia Garcia, A" uniqKey="Garcia Garcia A">A Garcia-Garcia</name></author><author><name sortKey="Gomez Marcos, Ma" uniqKey="Gomez Marcos M">MA Gomez-Marcos</name></author><author><name sortKey="Recio Rodriguez, Ji" uniqKey="Recio Rodriguez J">JI Recio-Rodriguez</name></author><author><name sortKey="Patino Alonso, Mc" uniqKey="Patino Alonso M">MC Patino-Alonso</name></author><author><name sortKey="Rodriguez Sanchez, E" uniqKey="Rodriguez Sanchez E">E Rodriguez-Sanchez</name></author><author><name sortKey="Agudo Conde, C" uniqKey="Agudo Conde C">C Agudo-Conde</name></author><author><name sortKey="Garcia Ortiz, L" uniqKey="Garcia Ortiz L">L Garcia-Ortiz</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="De Luca, N" uniqKey="De Luca N">N De Luca</name></author><author><name sortKey="Izzo, R" uniqKey="Izzo R">R Izzo</name></author><author><name sortKey="Iaccarino, G" uniqKey="Iaccarino G">G Iaccarino</name></author><author><name sortKey="Malini, Pl" uniqKey="Malini P">PL Malini</name></author><author><name sortKey="Morisco, C" uniqKey="Morisco C">C Morisco</name></author><author><name sortKey="Rozza, F" uniqKey="Rozza F">F Rozza</name></author><author><name sortKey="Iovino, Gl" uniqKey="Iovino G">GL Iovino</name></author><author><name sortKey="Rao, Ma" uniqKey="Rao M">MA Rao</name></author><author><name sortKey="Bodenizza, C" uniqKey="Bodenizza C">C Bodenizza</name></author><author><name sortKey="Lanni, F" uniqKey="Lanni F">F Lanni</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Izzo, R" uniqKey="Izzo R">R Izzo</name></author><author><name sortKey="De Simone, G" uniqKey="De Simone G">G de Simone</name></author><author><name sortKey="Chinali, M" uniqKey="Chinali M">M Chinali</name></author><author><name sortKey="Iaccarino, G" uniqKey="Iaccarino G">G Iaccarino</name></author><author><name sortKey="Trimarco, V" uniqKey="Trimarco V">V Trimarco</name></author><author><name sortKey="Rozza, F" uniqKey="Rozza F">F Rozza</name></author><author><name sortKey="Giudice, R" uniqKey="Giudice R">R Giudice</name></author><author><name sortKey="Trimarco, B" uniqKey="Trimarco B">B Trimarco</name></author><author><name sortKey="De Luca, N" uniqKey="De Luca N">N De Luca</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mancia, G" uniqKey="Mancia G">G Mancia</name></author><author><name sortKey="De Backer, G" uniqKey="De Backer G">G De 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DeMaria</name></author><author><name sortKey="Kisslo, J" uniqKey="Kisslo J">J Kisslo</name></author><author><name sortKey="Weyman, A" uniqKey="Weyman A">A Weyman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Iaccarino, G" uniqKey="Iaccarino G">G Iaccarino</name></author><author><name sortKey="Izzo, R" uniqKey="Izzo R">R Izzo</name></author><author><name sortKey="Trimarco, V" uniqKey="Trimarco V">V Trimarco</name></author><author><name sortKey="Cipolletta, E" uniqKey="Cipolletta E">E Cipolletta</name></author><author><name sortKey="Lanni, F" uniqKey="Lanni F">F Lanni</name></author><author><name sortKey="Sorriento, D" uniqKey="Sorriento D">D Sorriento</name></author><author><name sortKey="Iovino, Gl" uniqKey="Iovino G">GL Iovino</name></author><author><name sortKey="Rozza, F" uniqKey="Rozza F">F Rozza</name></author><author><name sortKey="De Luca, N" uniqKey="De Luca N">N De Luca</name></author><author><name sortKey="Priante, O" uniqKey="Priante 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Devereux</name></author><author><name sortKey="Alonso, Dr" uniqKey="Alonso D">DR Alonso</name></author><author><name sortKey="Lutas, Em" uniqKey="Lutas E">EM Lutas</name></author><author><name sortKey="Gottlieb, Gj" uniqKey="Gottlieb G">GJ Gottlieb</name></author><author><name sortKey="Campo, E" uniqKey="Campo E">E Campo</name></author><author><name sortKey="Sachs, I" uniqKey="Sachs I">I Sachs</name></author><author><name sortKey="Reichek, N" uniqKey="Reichek N">N Reichek</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lang, Rm" uniqKey="Lang R">RM Lang</name></author><author><name sortKey="Bierig, M" uniqKey="Bierig M">M Bierig</name></author><author><name sortKey="Devereux, Rb" uniqKey="Devereux R">RB Devereux</name></author><author><name sortKey="Flachskampf, Fa" uniqKey="Flachskampf F">FA Flachskampf</name></author><author><name sortKey="Foster, E" uniqKey="Foster E">E Foster</name></author><author><name sortKey="Pellikka, Pa" uniqKey="Pellikka P">PA Pellikka</name></author><author><name sortKey="Picard, Mh" uniqKey="Picard M">MH Picard</name></author><author><name sortKey="Roman, Mj" uniqKey="Roman M">MJ Roman</name></author><author><name sortKey="Seward, J" uniqKey="Seward J">J Seward</name></author><author><name sortKey="Shanewise, Js" uniqKey="Shanewise J">JS Shanewise</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="De Luca, N" uniqKey="De Luca N">N de Luca</name></author><author><name sortKey="Asmar, Rg" uniqKey="Asmar R">RG Asmar</name></author><author><name sortKey="London, Gm" uniqKey="London G">GM London</name></author><author><name sortKey="O Rourke, Mf" uniqKey="O Rourke M">MF O'Rourke</name></author><author><name sortKey="Safar, Me" uniqKey="Safar M">ME Safar</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lembo, G" uniqKey="Lembo G">G Lembo</name></author><author><name sortKey="De Luca, N" uniqKey="De Luca N">N De Luca</name></author><author><name sortKey="Battagli, C" uniqKey="Battagli C">C Battagli</name></author><author><name sortKey="Iovino, G" uniqKey="Iovino G">G Iovino</name></author><author><name sortKey="Aretini, A" uniqKey="Aretini A">A Aretini</name></author><author><name sortKey="Musicco, M" uniqKey="Musicco M">M Musicco</name></author><author><name sortKey="Frati, G" uniqKey="Frati G">G Frati</name></author><author><name sortKey="Pompeo, F" uniqKey="Pompeo F">F Pompeo</name></author><author><name sortKey="Vecchione, C" uniqKey="Vecchione C">C Vecchione</name></author><author><name sortKey="Trimarco, B" uniqKey="Trimarco B">B Trimarco</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Levey, As" uniqKey="Levey A">AS Levey</name></author><author><name sortKey="Eckardt, K U" uniqKey="Eckardt K">K-U Eckardt</name></author><author><name sortKey="Tsukamoto, Y" uniqKey="Tsukamoto Y">Y TSukamoto</name></author><author><name sortKey="Levin, A" uniqKey="Levin A">A Levin</name></author><author><name sortKey="Coresh, J" uniqKey="Coresh J">J Coresh</name></author><author><name sortKey="Rossert, J" uniqKey="Rossert J">J Rossert</name></author><author><name sortKey="Zeeuw, D" uniqKey="Zeeuw D">D Zeeuw</name></author><author><name sortKey="Hostetter, Th" uniqKey="Hostetter T">TH Hostetter</name></author><author><name sortKey="Lameire, N" uniqKey="Lameire N">N Lameire</name></author><author><name sortKey="Eknoyan, G" uniqKey="Eknoyan G">G Eknoyan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hamilton, P" uniqKey="Hamilton P">P Hamilton</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Goldberger, Al" uniqKey="Goldberger A">AL Goldberger</name></author><author><name sortKey="Amaral, Lan" uniqKey="Amaral L">LAN Amaral</name></author><author><name sortKey="Glass, L" uniqKey="Glass L">L Glass</name></author><author><name sortKey="Hausdorff, Jm" uniqKey="Hausdorff J">JM Hausdorff</name></author><author><name sortKey="Ivanov, Pc" uniqKey="Ivanov P">PC Ivanov</name></author><author><name sortKey="Mark, Rg" uniqKey="Mark R">RG Mark</name></author><author><name sortKey="Mietus, Je" uniqKey="Mietus J">JE Mietus</name></author><author><name sortKey="Moody, Gb" uniqKey="Moody G">GB Moody</name></author><author><name sortKey="Peng, C K" uniqKey="Peng C">C-K Peng</name></author><author><name sortKey="Stanley, He" uniqKey="Stanley H">HE Stanley</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Schroeder, Eb" uniqKey="Schroeder E">EB Schroeder</name></author><author><name sortKey="Liao, D" uniqKey="Liao D">D Liao</name></author><author><name sortKey="Chambless, Le" uniqKey="Chambless L">LE Chambless</name></author><author><name sortKey="Prineas, Rj" uniqKey="Prineas R">RJ Prineas</name></author><author><name sortKey="Evans, Gw" uniqKey="Evans G">GW Evans</name></author><author><name sortKey="Heiss, G" uniqKey="Heiss G">G Heiss</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Berntsen, Rf" uniqKey="Berntsen R">RF Berntsen</name></author><author><name sortKey="Bonaa, Kh" uniqKey="Bonaa K">KH Bonaa</name></author><author><name sortKey="Huikuri, Hv" uniqKey="Huikuri H">HV Huikuri</name></author><author><name sortKey="Rasmussen, K" uniqKey="Rasmussen K">K Rasmussen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Melillo, P" uniqKey="Melillo P">P Melillo</name></author><author><name sortKey="Bracale, M" uniqKey="Bracale M">M Bracale</name></author><author><name sortKey="Pecchia, L" uniqKey="Pecchia L">L Pecchia</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kodituwakku, S" uniqKey="Kodituwakku S">S Kodituwakku</name></author><author><name sortKey="Lazar, S" uniqKey="Lazar S">S Lazar</name></author><author><name sortKey="Indic, P" 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Greiser</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pecchia, L" uniqKey="Pecchia L">L Pecchia</name></author><author><name sortKey="Melillo, P" uniqKey="Melillo P">P Melillo</name></author><author><name sortKey="Bracale, M" uniqKey="Bracale M">M Bracale</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Melillo, P" uniqKey="Melillo P">P Melillo</name></author><author><name sortKey="Pecchia, L" uniqKey="Pecchia L">L Pecchia</name></author><author><name sortKey="Testa, F" uniqKey="Testa F">F Testa</name></author><author><name sortKey="Rossi, S" uniqKey="Rossi S">S Rossi</name></author><author><name sortKey="Bennett, J" uniqKey="Bennett J">J Bennett</name></author><author><name sortKey="Simonelli, F" uniqKey="Simonelli F">F Simonelli</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ferrari, G" uniqKey="Ferrari G">G Ferrari</name></author><author><name sortKey="Marques, J" uniqKey="Marques J">J Marques</name></author><author><name sortKey="Gandhi, R" uniqKey="Gandhi R">R Gandhi</name></author><author><name sortKey="Heller, S" uniqKey="Heller S">S Heller</name></author><author><name sortKey="Schneider, F" uniqKey="Schneider F">F Schneider</name></author><author><name sortKey="Tesfaye, S" uniqKey="Tesfaye S">S Tesfaye</name></author><author><name sortKey="Gamba, H" uniqKey="Gamba H">H Gamba</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kitzman, Dw" uniqKey="Kitzman D">DW Kitzman</name></author><author><name sortKey="Edwards, Wd" uniqKey="Edwards W">WD Edwards</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zabalgoitia, M" uniqKey="Zabalgoitia M">M Zabalgoitia</name></author><author><name sortKey="Rahman, Sn" uniqKey="Rahman S">SN Rahman</name></author><author><name sortKey="Haley, We" uniqKey="Haley W">WE Haley</name></author><author><name sortKey="Mercado, R" uniqKey="Mercado R">R Mercado</name></author><author><name sortKey="Yunis, C" uniqKey="Yunis C">C Yunis</name></author><author><name sortKey="Lucas, C" uniqKey="Lucas C">C Lucas</name></author><author><name sortKey="Yarows, S" uniqKey="Yarows S">S Yarows</name></author><author><name sortKey="Krause, L" uniqKey="Krause L">L Krause</name></author><author><name sortKey="Amarena, J" uniqKey="Amarena J">J Amarena</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Dahlof, B" uniqKey="Dahlof B">B Dahlof</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jensen Urstad, K" uniqKey="Jensen Urstad K">K Jensen-Urstad</name></author><author><name sortKey="Storck, N" uniqKey="Storck N">N Storck</name></author><author><name sortKey="Bouvier, F" uniqKey="Bouvier F">F Bouvier</name></author><author><name sortKey="Ericson, M" uniqKey="Ericson M">M Ericson</name></author><author><name sortKey="Lindbland, Le" uniqKey="Lindbland L">LE Lindbland</name></author><author><name sortKey="Jensen Urstad, M" uniqKey="Jensen Urstad M">M Jensen-Urstad</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bajko, Z" uniqKey="Bajko Z">Z Bajko</name></author><author><name sortKey="Szekeres, Cc" uniqKey="Szekeres C">CC Szekeres</name></author><author><name sortKey="Kovacs, Kr" uniqKey="Kovacs K">KR Kovacs</name></author><author><name sortKey="Csapo, K" uniqKey="Csapo K">K Csapo</name></author><author><name sortKey="Molnar, S" uniqKey="Molnar S">S Molnar</name></author><author><name sortKey="Soltesz, P" uniqKey="Soltesz P">P Soltesz</name></author><author><name sortKey="Nyitrai, E" uniqKey="Nyitrai E">E Nyitrai</name></author><author><name sortKey="Magyar, Mt" uniqKey="Magyar M">MT Magyar</name></author><author><name sortKey="Olah, L" uniqKey="Olah L">L Olah</name></author><author><name sortKey="Bereczki, D" uniqKey="Bereczki D">D Bereczki</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Italie</li><li>Royaume-Uni</li></country><region><li>Angleterre</li><li>Nottinghamshire</li></region><settlement><li>Nottingham</li></settlement><orgName><li>Université de Nottingham</li></orgName></list><tree><country name="Italie"><noRegion><name sortKey="Melillo, Paolo" sort="Melillo, Paolo" uniqKey="Melillo P" first="Paolo" last="Melillo">Paolo Melillo</name></noRegion><name sortKey="De Luca, Nicola" sort="De Luca, Nicola" uniqKey="De Luca N" first="Nicola" last="De Luca">Nicola De Luca</name><name sortKey="Izzo, Raffaele" sort="Izzo, Raffaele" uniqKey="Izzo R" first="Raffaele" last="Izzo">Raffaele Izzo</name></country><country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Pecchia, Leandro" sort="Pecchia, Leandro" uniqKey="Pecchia L" first="Leandro" last="Pecchia">Leandro Pecchia</name></region></country></tree></affiliations></record>Pour manipuler ce 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