Plasmacytoid Dendritic Cells Reduce HIV Production in Elite Controllers
Identifieur interne : 000556 ( Main/Exploration ); précédent : 000555; suivant : 000557Plasmacytoid Dendritic Cells Reduce HIV Production in Elite Controllers
Auteurs : K. Machmach [Espagne] ; M. Leal [Espagne] ; C. Gras [France] ; P. Viciana [Espagne] ; M. Genebat [Espagne] ; E. Franco [Espagne] ; F. Boufassa ; O. Lambotte [France] ; J. P. Herbeuval [France] ; E. Ruiz-Mateos [Espagne]Source :
- Journal of Virology [ 0022-538X ] ; 2012.
Abstract
HIV elite controllers (EC) are a rare group of HIV-infected patients who are able to maintain undetectable viral loads during a long period of time in the absence of antiretroviral treatment. Adaptive immunity and host genetic factors, although implicated, do not entirely explain this phenomenon. On the other hand, plasmacytoid dendritic cells (pDCs) are the principal type I interferon (IFN) producers in response to viral infection, and it is unknown whether pDCs are involved in the control of HIV infection in EC. In our study, we analyzed peripheral pDC levels and IFN-α production by peripheral blood mononuclear cells (PBMCs) in EC compared to other groups of HIV-infected patients, the ability of pDCs to reduce HIV production
Url:
DOI: 10.1128/JVI.07114-11
PubMed: 22318133
PubMed Central: 3318617
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 000392
- to stream Pmc, to step Curation: 000392
- to stream Pmc, to step Checkpoint: 000292
- to stream Ncbi, to step Merge: 000781
- to stream Ncbi, to step Curation: 000781
- to stream Ncbi, to step Checkpoint: 000781
- to stream Main, to step Merge: 000556
- to stream Main, to step Curation: 000556
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Plasmacytoid Dendritic Cells Reduce HIV Production in Elite Controllers</title>
<author><name sortKey="Machmach, K" sort="Machmach, K" uniqKey="Machmach K" first="K." last="Machmach">K. Machmach</name>
<affiliation wicri:level="1"><nlm:aff id="aff1">Laboratory of Immunovirology, Biomedicine Institute of Seville (IBIS), Infectious Diseases Service, Virgen del Rocío University Hospital, Seville, Spain</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Laboratory of Immunovirology, Biomedicine Institute of Seville (IBIS), Infectious Diseases Service, Virgen del Rocío University Hospital, Seville</wicri:regionArea>
<wicri:noRegion>Seville</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff2">Biochemistry Department, Virgen del Rocío University Hospital, Seville, Spain</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Biochemistry Department, Virgen del Rocío University Hospital, Seville</wicri:regionArea>
<wicri:noRegion>Seville</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Leal, M" sort="Leal, M" uniqKey="Leal M" first="M." last="Leal">M. Leal</name>
<affiliation wicri:level="1"><nlm:aff id="aff1">Laboratory of Immunovirology, Biomedicine Institute of Seville (IBIS), Infectious Diseases Service, Virgen del Rocío University Hospital, Seville, Spain</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Laboratory of Immunovirology, Biomedicine Institute of Seville (IBIS), Infectious Diseases Service, Virgen del Rocío University Hospital, Seville</wicri:regionArea>
<wicri:noRegion>Seville</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff2">Biochemistry Department, Virgen del Rocío University Hospital, Seville, Spain</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Biochemistry Department, Virgen del Rocío University Hospital, Seville</wicri:regionArea>
<wicri:noRegion>Seville</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Gras, C" sort="Gras, C" uniqKey="Gras C" first="C." last="Gras">C. Gras</name>
<affiliation wicri:level="4"><nlm:aff id="aff3">CNRS UMR 8147, Université Paris Descartes, Paris, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>CNRS UMR 8147, Université Paris Descartes, Paris</wicri:regionArea>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
<orgName type="university">Université Paris-Descartes</orgName>
</affiliation>
</author>
<author><name sortKey="Viciana, P" sort="Viciana, P" uniqKey="Viciana P" first="P." last="Viciana">P. Viciana</name>
<affiliation wicri:level="1"><nlm:aff id="aff1">Laboratory of Immunovirology, Biomedicine Institute of Seville (IBIS), Infectious Diseases Service, Virgen del Rocío University Hospital, Seville, Spain</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Laboratory of Immunovirology, Biomedicine Institute of Seville (IBIS), Infectious Diseases Service, Virgen del Rocío University Hospital, Seville</wicri:regionArea>
<wicri:noRegion>Seville</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Genebat, M" sort="Genebat, M" uniqKey="Genebat M" first="M." last="Genebat">M. Genebat</name>
<affiliation wicri:level="1"><nlm:aff id="aff1">Laboratory of Immunovirology, Biomedicine Institute of Seville (IBIS), Infectious Diseases Service, Virgen del Rocío University Hospital, Seville, Spain</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Laboratory of Immunovirology, Biomedicine Institute of Seville (IBIS), Infectious Diseases Service, Virgen del Rocío University Hospital, Seville</wicri:regionArea>
<wicri:noRegion>Seville</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Franco, E" sort="Franco, E" uniqKey="Franco E" first="E." last="Franco">E. Franco</name>
<affiliation wicri:level="1"><nlm:aff id="aff4">Centro Regional de Transfusiones Sanguíneas Sevilla/Huelva y Banco de Tejidos, Seville, Spain</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Centro Regional de Transfusiones Sanguíneas Sevilla/Huelva y Banco de Tejidos, Seville</wicri:regionArea>
<wicri:noRegion>Seville</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Boufassa, F" sort="Boufassa, F" uniqKey="Boufassa F" first="F." last="Boufassa">F. Boufassa</name>
<affiliation><nlm:aff id="aff5">INSERM U1012, Bicêtre</nlm:aff>
<wicri:noCountry code="subfield">Bicêtre</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Lambotte, O" sort="Lambotte, O" uniqKey="Lambotte O" first="O." last="Lambotte">O. Lambotte</name>
<affiliation><nlm:aff id="aff5">INSERM U1012, Bicêtre</nlm:aff>
<wicri:noCountry code="subfield">Bicêtre</wicri:noCountry>
</affiliation>
<affiliation><nlm:aff id="aff6">AP-HP, Department of Internal Medicine and Infectious Diseases, Bicêtre Hospital, Bicêtre</nlm:aff>
<wicri:noCountry code="subfield">Bicêtre</wicri:noCountry>
</affiliation>
<affiliation wicri:level="4"><nlm:aff id="aff7">Université Paris-Sud, U1012, Bicêtre, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Université Paris-Sud, U1012, Bicêtre</wicri:regionArea>
<wicri:noRegion>Bicêtre</wicri:noRegion>
<orgName type="university">Université Paris-Sud</orgName>
<placeName><settlement type="city">Orsay</settlement>
<region type="region" nuts="2">Île-de-France</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Herbeuval, J P" sort="Herbeuval, J P" uniqKey="Herbeuval J" first="J. P." last="Herbeuval">J. P. Herbeuval</name>
<affiliation wicri:level="4"><nlm:aff id="aff3">CNRS UMR 8147, Université Paris Descartes, Paris, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>CNRS UMR 8147, Université Paris Descartes, Paris</wicri:regionArea>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
<orgName type="university">Université Paris-Descartes</orgName>
</affiliation>
</author>
<author><name sortKey="Ruiz Mateos, E" sort="Ruiz Mateos, E" uniqKey="Ruiz Mateos E" first="E." last="Ruiz-Mateos">E. Ruiz-Mateos</name>
<affiliation wicri:level="1"><nlm:aff id="aff1">Laboratory of Immunovirology, Biomedicine Institute of Seville (IBIS), Infectious Diseases Service, Virgen del Rocío University Hospital, Seville, Spain</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Laboratory of Immunovirology, Biomedicine Institute of Seville (IBIS), Infectious Diseases Service, Virgen del Rocío University Hospital, Seville</wicri:regionArea>
<wicri:noRegion>Seville</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff2">Biochemistry Department, Virgen del Rocío University Hospital, Seville, Spain</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Biochemistry Department, Virgen del Rocío University Hospital, Seville</wicri:regionArea>
<wicri:noRegion>Seville</wicri:noRegion>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">22318133</idno>
<idno type="pmc">3318617</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3318617</idno>
<idno type="RBID">PMC:3318617</idno>
<idno type="doi">10.1128/JVI.07114-11</idno>
<date when="2012">2012</date>
<idno type="wicri:Area/Pmc/Corpus">000392</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000392</idno>
<idno type="wicri:Area/Pmc/Curation">000392</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000392</idno>
<idno type="wicri:Area/Pmc/Checkpoint">000292</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000292</idno>
<idno type="wicri:Area/Ncbi/Merge">000781</idno>
<idno type="wicri:Area/Ncbi/Curation">000781</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">000781</idno>
<idno type="wicri:doubleKey">0022-538X:2012:Machmach K:plasmacytoid:dendritic:cells</idno>
<idno type="wicri:Area/Main/Merge">000556</idno>
<idno type="wicri:Area/Main/Curation">000556</idno>
<idno type="wicri:Area/Main/Exploration">000556</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Plasmacytoid Dendritic Cells Reduce HIV Production in Elite Controllers</title>
<author><name sortKey="Machmach, K" sort="Machmach, K" uniqKey="Machmach K" first="K." last="Machmach">K. Machmach</name>
<affiliation wicri:level="1"><nlm:aff id="aff1">Laboratory of Immunovirology, Biomedicine Institute of Seville (IBIS), Infectious Diseases Service, Virgen del Rocío University Hospital, Seville, Spain</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Laboratory of Immunovirology, Biomedicine Institute of Seville (IBIS), Infectious Diseases Service, Virgen del Rocío University Hospital, Seville</wicri:regionArea>
<wicri:noRegion>Seville</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff2">Biochemistry Department, Virgen del Rocío University Hospital, Seville, Spain</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Biochemistry Department, Virgen del Rocío University Hospital, Seville</wicri:regionArea>
<wicri:noRegion>Seville</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Leal, M" sort="Leal, M" uniqKey="Leal M" first="M." last="Leal">M. Leal</name>
<affiliation wicri:level="1"><nlm:aff id="aff1">Laboratory of Immunovirology, Biomedicine Institute of Seville (IBIS), Infectious Diseases Service, Virgen del Rocío University Hospital, Seville, Spain</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Laboratory of Immunovirology, Biomedicine Institute of Seville (IBIS), Infectious Diseases Service, Virgen del Rocío University Hospital, Seville</wicri:regionArea>
<wicri:noRegion>Seville</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff2">Biochemistry Department, Virgen del Rocío University Hospital, Seville, Spain</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Biochemistry Department, Virgen del Rocío University Hospital, Seville</wicri:regionArea>
<wicri:noRegion>Seville</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Gras, C" sort="Gras, C" uniqKey="Gras C" first="C." last="Gras">C. Gras</name>
<affiliation wicri:level="4"><nlm:aff id="aff3">CNRS UMR 8147, Université Paris Descartes, Paris, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>CNRS UMR 8147, Université Paris Descartes, Paris</wicri:regionArea>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
<orgName type="university">Université Paris-Descartes</orgName>
</affiliation>
</author>
<author><name sortKey="Viciana, P" sort="Viciana, P" uniqKey="Viciana P" first="P." last="Viciana">P. Viciana</name>
<affiliation wicri:level="1"><nlm:aff id="aff1">Laboratory of Immunovirology, Biomedicine Institute of Seville (IBIS), Infectious Diseases Service, Virgen del Rocío University Hospital, Seville, Spain</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Laboratory of Immunovirology, Biomedicine Institute of Seville (IBIS), Infectious Diseases Service, Virgen del Rocío University Hospital, Seville</wicri:regionArea>
<wicri:noRegion>Seville</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Genebat, M" sort="Genebat, M" uniqKey="Genebat M" first="M." last="Genebat">M. Genebat</name>
<affiliation wicri:level="1"><nlm:aff id="aff1">Laboratory of Immunovirology, Biomedicine Institute of Seville (IBIS), Infectious Diseases Service, Virgen del Rocío University Hospital, Seville, Spain</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Laboratory of Immunovirology, Biomedicine Institute of Seville (IBIS), Infectious Diseases Service, Virgen del Rocío University Hospital, Seville</wicri:regionArea>
<wicri:noRegion>Seville</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Franco, E" sort="Franco, E" uniqKey="Franco E" first="E." last="Franco">E. Franco</name>
<affiliation wicri:level="1"><nlm:aff id="aff4">Centro Regional de Transfusiones Sanguíneas Sevilla/Huelva y Banco de Tejidos, Seville, Spain</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Centro Regional de Transfusiones Sanguíneas Sevilla/Huelva y Banco de Tejidos, Seville</wicri:regionArea>
<wicri:noRegion>Seville</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Boufassa, F" sort="Boufassa, F" uniqKey="Boufassa F" first="F." last="Boufassa">F. Boufassa</name>
<affiliation><nlm:aff id="aff5">INSERM U1012, Bicêtre</nlm:aff>
<wicri:noCountry code="subfield">Bicêtre</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Lambotte, O" sort="Lambotte, O" uniqKey="Lambotte O" first="O." last="Lambotte">O. Lambotte</name>
<affiliation><nlm:aff id="aff5">INSERM U1012, Bicêtre</nlm:aff>
<wicri:noCountry code="subfield">Bicêtre</wicri:noCountry>
</affiliation>
<affiliation><nlm:aff id="aff6">AP-HP, Department of Internal Medicine and Infectious Diseases, Bicêtre Hospital, Bicêtre</nlm:aff>
<wicri:noCountry code="subfield">Bicêtre</wicri:noCountry>
</affiliation>
<affiliation wicri:level="4"><nlm:aff id="aff7">Université Paris-Sud, U1012, Bicêtre, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Université Paris-Sud, U1012, Bicêtre</wicri:regionArea>
<wicri:noRegion>Bicêtre</wicri:noRegion>
<orgName type="university">Université Paris-Sud</orgName>
<placeName><settlement type="city">Orsay</settlement>
<region type="region" nuts="2">Île-de-France</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Herbeuval, J P" sort="Herbeuval, J P" uniqKey="Herbeuval J" first="J. P." last="Herbeuval">J. P. Herbeuval</name>
<affiliation wicri:level="4"><nlm:aff id="aff3">CNRS UMR 8147, Université Paris Descartes, Paris, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>CNRS UMR 8147, Université Paris Descartes, Paris</wicri:regionArea>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
<orgName type="university">Université Paris-Descartes</orgName>
</affiliation>
</author>
<author><name sortKey="Ruiz Mateos, E" sort="Ruiz Mateos, E" uniqKey="Ruiz Mateos E" first="E." last="Ruiz-Mateos">E. Ruiz-Mateos</name>
<affiliation wicri:level="1"><nlm:aff id="aff1">Laboratory of Immunovirology, Biomedicine Institute of Seville (IBIS), Infectious Diseases Service, Virgen del Rocío University Hospital, Seville, Spain</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Laboratory of Immunovirology, Biomedicine Institute of Seville (IBIS), Infectious Diseases Service, Virgen del Rocío University Hospital, Seville</wicri:regionArea>
<wicri:noRegion>Seville</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff2">Biochemistry Department, Virgen del Rocío University Hospital, Seville, Spain</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Biochemistry Department, Virgen del Rocío University Hospital, Seville</wicri:regionArea>
<wicri:noRegion>Seville</wicri:noRegion>
</affiliation>
</author>
</analytic>
<series><title level="j">Journal of Virology</title>
<idno type="ISSN">0022-538X</idno>
<idno type="eISSN">1098-5514</idno>
<imprint><date when="2012">2012</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><p>HIV elite controllers (EC) are a rare group of HIV-infected patients who are able to maintain undetectable viral loads during a long period of time in the absence of antiretroviral treatment. Adaptive immunity and host genetic factors, although implicated, do not entirely explain this phenomenon. On the other hand, plasmacytoid dendritic cells (pDCs) are the principal type I interferon (IFN) producers in response to viral infection, and it is unknown whether pDCs are involved in the control of HIV infection in EC. In our study, we analyzed peripheral pDC levels and IFN-α production by peripheral blood mononuclear cells (PBMCs) in EC compared to other groups of HIV-infected patients, the ability of pDCs to reduce HIV production <italic>in vitro</italic>
, and the mechanisms potentially involved. We showed preserved pDC counts and IFN-α production in EC. We also observed a higher capacity of pDCs from EC to reduce HIV production and to induce T cell apoptosis, whereas pDCs from viremic patients barely responded without previous Toll-like receptor 9 (TLR-9) stimulus. The preserved functionality of pDCs from EC to reduce viral production may be one of the mechanisms involved in the control of HIV viremia in these subjects. These results demonstrate the importance of innate immunity in HIV pathogenesis, and an understanding of pDC mechanisms would be helpful for the design of new therapies.</p>
</div>
</front>
</TEI>
<affiliations><list><country><li>Espagne</li>
<li>France</li>
</country>
<region><li>Île-de-France</li>
</region>
<settlement><li>Orsay</li>
<li>Paris</li>
</settlement>
<orgName><li>Université Paris-Descartes</li>
<li>Université Paris-Sud</li>
</orgName>
</list>
<tree><noCountry><name sortKey="Boufassa, F" sort="Boufassa, F" uniqKey="Boufassa F" first="F." last="Boufassa">F. Boufassa</name>
</noCountry>
<country name="Espagne"><noRegion><name sortKey="Machmach, K" sort="Machmach, K" uniqKey="Machmach K" first="K." last="Machmach">K. Machmach</name>
</noRegion>
<name sortKey="Franco, E" sort="Franco, E" uniqKey="Franco E" first="E." last="Franco">E. Franco</name>
<name sortKey="Genebat, M" sort="Genebat, M" uniqKey="Genebat M" first="M." last="Genebat">M. Genebat</name>
<name sortKey="Leal, M" sort="Leal, M" uniqKey="Leal M" first="M." last="Leal">M. Leal</name>
<name sortKey="Leal, M" sort="Leal, M" uniqKey="Leal M" first="M." last="Leal">M. Leal</name>
<name sortKey="Machmach, K" sort="Machmach, K" uniqKey="Machmach K" first="K." last="Machmach">K. Machmach</name>
<name sortKey="Ruiz Mateos, E" sort="Ruiz Mateos, E" uniqKey="Ruiz Mateos E" first="E." last="Ruiz-Mateos">E. Ruiz-Mateos</name>
<name sortKey="Ruiz Mateos, E" sort="Ruiz Mateos, E" uniqKey="Ruiz Mateos E" first="E." last="Ruiz-Mateos">E. Ruiz-Mateos</name>
<name sortKey="Viciana, P" sort="Viciana, P" uniqKey="Viciana P" first="P." last="Viciana">P. Viciana</name>
</country>
<country name="France"><region name="Île-de-France"><name sortKey="Gras, C" sort="Gras, C" uniqKey="Gras C" first="C." last="Gras">C. Gras</name>
</region>
<name sortKey="Herbeuval, J P" sort="Herbeuval, J P" uniqKey="Herbeuval J" first="J. P." last="Herbeuval">J. P. Herbeuval</name>
<name sortKey="Lambotte, O" sort="Lambotte, O" uniqKey="Lambotte O" first="O." last="Lambotte">O. Lambotte</name>
</country>
</tree>
</affiliations>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Ticri/CIDE/explor/TelematiV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000556 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000556 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Ticri/CIDE |area= TelematiV1 |flux= Main |étape= Exploration |type= RBID |clé= PMC:3318617 |texte= Plasmacytoid Dendritic Cells Reduce HIV Production in Elite Controllers }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:22318133" \ | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \ | NlmPubMed2Wicri -a TelematiV1
This area was generated with Dilib version V0.6.31. |