Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.
Identifieur interne : 000006 ( PubMed/Checkpoint ); précédent : 000005; suivant : 000007Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.
Auteurs : Wesley C. Van Voorhis [États-Unis] ; John H. Adams [États-Unis] ; Roberto Adelfio [Suisse] ; Vida Ahyong [États-Unis] ; Myles H. Akabas [États-Unis] ; Pietro Alano [Italie] ; Aintzane Alday [Espagne] ; Yesmalie Alemán Resto [États-Unis] ; Aishah Alsibaee [Irlande (pays)] ; Ainhoa Alzualde [Espagne] ; Katherine T. Andrews [Australie] ; Simon V. Avery [Royaume-Uni] ; Vicky M. Avery [Australie] ; Lawrence Ayong [Corée du Sud] ; Mark Baker [Suisse] ; Stephen Baker [Viêt Nam] ; Choukri Ben Mamoun [États-Unis] ; Sangeeta Bhatia [États-Unis] ; Quentin Bickle [Royaume-Uni] ; Lotfi Bounaadja [France] ; Tana Bowling [États-Unis] ; Jürgen Bosch ; Lauren E. Boucher ; Fabrice F. Boyom [Cameroun] ; Jose Brea [Espagne] ; Marian Brennan [Irlande (pays)] ; Audrey Burton [États-Unis] ; Conor R. Caffrey [États-Unis] ; Grazia Camarda [Italie] ; Manuela Carrasquilla [États-Unis] ; Dee Carter [Australie] ; Maria Belen Cassera [États-Unis] ; Ken Chih-Chien Cheng [États-Unis] ; Worathad Chindaudomsate [Thaïlande] ; Anthony Chubb [Irlande (pays)] ; Beatrice L. Colon [États-Unis] ; Daisy D. Col N-L Pez ; Yolanda Corbett [Italie] ; Gregory J. Crowther [États-Unis] ; Noemi Cowan [Suisse] ; Sarah D'Alessandro [Italie] ; Na Le Dang [États-Unis] ; Michael Delves [Royaume-Uni] ; Joseph L. Derisi [États-Unis] ; Alan Y. Du [États-Unis] ; Sandra Duffy [Australie] ; Shimaa Abd El-Salam El-Sayed [Japon] ; Michael T. Ferdig [États-Unis] ; José A. Fernández Robledo [États-Unis] ; David A. Fidock [États-Unis] ; Isabelle Florent [France] ; Patrick V T. Fokou [Cameroun] ; Ani Galstian [États-Unis] ; Francisco Javier Gamo [Espagne] ; Suzanne Gokool [Royaume-Uni] ; Ben Gold [États-Unis] ; Todd Golub [États-Unis] ; Gregory M. Goldgof [États-Unis] ; Rajarshi Guha [États-Unis] ; W Armand Guiguemde [États-Unis] ; Nil Gural [États-Unis] ; R Kiplin Guy [États-Unis] ; Michael A E. Hansen [Corée du Sud] ; Kirsten K. Hanson [États-Unis] ; Andrew Hemphill [Suisse] ; Rob Hooft Van Huijsduijnen [Suisse] ; Takaaki Horii [Japon] ; Paul Horrocks [Royaume-Uni] ; Tyler B. Hughes [États-Unis] ; Christopher Huston [États-Unis] ; Ikuo Igarashi [Japon] ; Katrin Ingram-Sieber [Suisse] ; Maurice A. Itoe [Portugal] ; Ajit Jadhav [États-Unis] ; Amornrat Naranuntarat Jensen ; Laran T. Jensen [Thaïlande] ; Rays H Y. Jiang [États-Unis] ; Annette Kaiser [Allemagne] ; Jennifer Keiser [Suisse] ; Thomas Ketas [États-Unis] ; Sebastien Kicka [Suisse] ; Sunyoung Kim [États-Unis] ; Kiaran Kirk [Australie] ; Vidya P. Kumar [États-Unis] ; Dennis E. Kyle [États-Unis] ; Maria Jose Lafuente [Espagne] ; Scott Landfear [États-Unis] ; Nathan Lee [Suisse] ; Sukjun Lee [Corée du Sud] ; Adele M. Lehane [Australie] ; Fengwu Li [États-Unis] ; David Little [États-Unis] ; Liqiong Liu [États-Unis] ; Manuel Llinás [États-Unis] ; Maria I. Loza [Espagne] ; Aristea Lubar [États-Unis] ; Leonardo Lucantoni [Australie] ; Isabelle Lucet [Australie] ; Louis Maes [Belgique] ; Dalu Mancama [Afrique du Sud] ; Nuha R. Mansour [Royaume-Uni] ; Sandra March [États-Unis] ; Sheena Mcgowan [Australie] ; Iset Medina Vera [Portugal] ; Stephan Meister [États-Unis] ; Luke Mercer [États-Unis] ; Jordi Mestres [Espagne] ; Alvine N. Mfopa [Cameroun] ; Raj N. Misra [États-Unis] ; Seunghyun Moon [Corée du Sud] ; John P. Moore [États-Unis] ; Francielly Morais Rodrigues Da Costa [Brésil] ; Joachim Müller [Suisse] ; Arantza Muriana [Espagne] ; Stephen Nakazawa Hewitt [États-Unis] ; Bakela Nare [États-Unis] ; Carl Nathan [États-Unis] ; Nathalie Narraidoo [Royaume-Uni] ; Sujeevi Nawaratna [Australie] ; Kayode K. Ojo [États-Unis] ; Diana Ortiz [États-Unis] ; Gordana Panic [Suisse] ; George Papadatos [Royaume-Uni] ; Silvia Parapini [Italie] ; Kailash Patra [États-Unis] ; Ngoc Pham [Australie] ; Sarah Prats [Espagne] ; David M. Plouffe [États-Unis] ; Sally-Ann Poulsen [Australie] ; Anupam Pradhan [États-Unis] ; Celia Quevedo [Espagne] ; Ronald J. Quinn [Australie] ; Christopher A. Rice [États-Unis] ; Mohamed Abdo Rizk [Japon] ; Andrea Ruecker [Royaume-Uni] ; Robert St Onge [États-Unis] ; Rafaela Salgado Ferreira [Brésil] ; Jasmeet Samra [États-Unis] ; Natalie G. Robinett ; Ulrich Schlecht [États-Unis] ; Marjorie Schmitt [France] ; Filipe Silva Villela [Brésil] ; Francesco Silvestrini [Italie] ; Robert Sinden [Royaume-Uni] ; Dennis A. Smith [Afrique du Sud] ; Thierry Soldati [Suisse] ; Andreas Spitzmüller [Espagne] ; Serge Maximilian Stamm ; David J. Sullivan [États-Unis] ; William Sullivan [États-Unis] ; Sundari Suresh [Brésil] ; Brian M. Suzuki [États-Unis] ; Yo Suzuki [États-Unis] ; S Joshua Swamidass [Royaume-Uni] ; Donatella Taramelli [États-Unis] ; Lauve R Y. Tchokouaha [Cameroun] ; Anjo Theron [Afrique du Sud] ; David Thomas [États-Unis] ; Kathryn F. Tonissen [Australie] ; Simon Townson [Royaume-Uni] ; Abhai K. Tripathi [États-Unis] ; Valentin Trofimov [Suisse] ; Kenneth O. Udenze [États-Unis] ; Imran Ullah [Royaume-Uni] ; Cindy Vallieres [Royaume-Uni] ; Edgar Vigil [États-Unis] ; Joseph M. Vinetz [États-Unis] ; Phat Voong Vinh [Viêt Nam] ; Hoan Vu [Australie] ; Nao-Aki Watanabe [Japon] ; Kate Weatherby [Australie] ; Pamela M. White [États-Unis] ; Andrew F. Wilks [Australie] ; Elizabeth A. Winzeler [États-Unis] ; Edward Wojcik [États-Unis] ; Melanie Wree [États-Unis] ; Wesley Wu [États-Unis] ; Naoaki Yokoyama [Japon] ; Paul H A. Zollo [Cameroun] ; Nada Abla [Suisse] ; Benjamin Blasco [Suisse] ; Jeremy Burrows [Suisse] ; Benoît Laleu [Suisse] ; Didier Leroy [Suisse] ; Thomas Spangenberg [Suisse] ; Timothy Wells [Suisse] ; Paul A. Willis [Suisse]Source :
- PLoS pathogens [ 1553-7374 ] ; 2016.
Abstract
A major cause of the paucity of new starting points for drug discovery is the lack of interaction between academia and industry. Much of the global resource in biology is present in universities, whereas the focus of medicinal chemistry is still largely within industry. Open source drug discovery, with sharing of information, is clearly a first step towards overcoming this gap. But the interface could especially be bridged through a scale-up of open sharing of physical compounds, which would accelerate the finding of new starting points for drug discovery. The Medicines for Malaria Venture Malaria Box is a collection of over 400 compounds representing families of structures identified in phenotypic screens of pharmaceutical and academic libraries against the Plasmodium falciparum malaria parasite. The set has now been distributed to almost 200 research groups globally in the last two years, with the only stipulation that information from the screens is deposited in the public domain. This paper reports for the first time on 236 screens that have been carried out against the Malaria Box and compares these results with 55 assays that were previously published, in a format that allows a meta-analysis of the combined dataset. The combined biochemical and cellular assays presented here suggest mechanisms of action for 135 (34%) of the compounds active in killing multiple life-cycle stages of the malaria parasite, including asexual blood, liver, gametocyte, gametes and insect ookinete stages. In addition, many compounds demonstrated activity against other pathogens, showing hits in assays with 16 protozoa, 7 helminths, 9 bacterial and mycobacterial species, the dengue fever mosquito vector, and the NCI60 human cancer cell line panel of 60 human tumor cell lines. Toxicological, pharmacokinetic and metabolic properties were collected on all the compounds, assisting in the selection of the most promising candidates for murine proof-of-concept experiments and medicinal chemistry programs. The data for all of these assays are presented and analyzed to show how outstanding leads for many indications can be selected. These results reveal the immense potential for translating the dispersed expertise in biological assays involving human pathogens into drug discovery starting points, by providing open access to new families of molecules, and emphasize how a small additional investment made to help acquire and distribute compounds, and sharing the data, can catalyze drug discovery for dozens of different indications. Another lesson is that when multiple screens from different groups are run on the same library, results can be integrated quickly to select the most valuable starting points for subsequent medicinal chemistry efforts.
DOI: 10.1371/journal.ppat.1005763
PubMed: 27467575
Affiliations:
- Afrique du Sud, Allemagne, Australie, Belgique, Brésil, Cameroun, Corée du Sud, Espagne, France, Irlande (pays), Italie, Japon, Portugal, Royaume-Uni, Suisse, Thaïlande, Viêt Nam, États-Unis
- Angleterre, Californie, Canton de Berne, Canton de Genève, Caroline du Nord, Communauté de Madrid, Connecticut, Floride, Galice, Latium, Louisiane, Maine (État), Maryland, Massachusetts, Minas Gerais, Missouri (État), Nottinghamshire, Oregon, Oxfordshire, Pennsylvanie, Province d'Anvers, Tennessee, Texas, Vermont, Virginie, Washington (État), État de New York
- Anvers, Belo Horizonte, Berne, Genève, Madrid, Nottingham, Oxford, Paris, Portland, Rome, Saint-Louis (Missouri), Santiago de Compostela, Seattle, Tampa, University Park (Pennsylvanie)
- Université Washington de Saint-Louis, Université d'Anvers, Université d'Oxford, Université d'État de Pennsylvanie, Université de Floride du Sud, Université de Genève, Université de Nottingham, Université de Saint-Jacques-de-Compostelle, Université de Washington, Université des sciences et de la médecine de l'Oregon, Université fédérale du Minas Gerais
Links toward previous steps (curation, corpus...)
Links to Exploration step
pubmed:27467575Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.</title>
<author><name sortKey="Van Voorhis, Wesley C" sort="Van Voorhis, Wesley C" uniqKey="Van Voorhis W" first="Wesley C" last="Van Voorhis">Wesley C. Van Voorhis</name>
<affiliation wicri:level="4"><nlm:affiliation>Departments of Medicine, Microbiology, and Global Health, Center for Emerging and Re-emerging Infectious Diseases (CERID) University of Washington, Seattle, Washington, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Departments of Medicine, Microbiology, and Global Health, Center for Emerging and Re-emerging Infectious Diseases (CERID) University of Washington, Seattle, Washington</wicri:regionArea>
<placeName><region type="state">Washington (État)</region>
<settlement type="city">Seattle</settlement>
</placeName>
<orgName type="university">Université de Washington</orgName>
</affiliation>
</author>
<author><name sortKey="Adams, John H" sort="Adams, John H" uniqKey="Adams J" first="John H" last="Adams">John H. Adams</name>
<affiliation wicri:level="4"><nlm:affiliation>Center for Global Health and Infectious Diseases Research, Department of Global Health, University of South Florida, Tampa, Florida, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Center for Global Health and Infectious Diseases Research, Department of Global Health, University of South Florida, Tampa, Florida</wicri:regionArea>
<placeName><region type="state">Floride</region>
<settlement type="city">Tampa</settlement>
</placeName>
<orgName type="university">Université de Floride du Sud</orgName>
</affiliation>
</author>
<author><name sortKey="Adelfio, Roberto" sort="Adelfio, Roberto" uniqKey="Adelfio R" first="Roberto" last="Adelfio">Roberto Adelfio</name>
<affiliation wicri:level="1"><nlm:affiliation>Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Basel, Switzerland.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Basel</wicri:regionArea>
<wicri:noRegion>Basel</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Ahyong, Vida" sort="Ahyong, Vida" uniqKey="Ahyong V" first="Vida" last="Ahyong">Vida Ahyong</name>
<affiliation wicri:level="2"><nlm:affiliation>Howard Hughes Medical Institute, Department of Biochemistry and Biophysics, University of California, San Francisco, California, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Howard Hughes Medical Institute, Department of Biochemistry and Biophysics, University of California, San Francisco, California</wicri:regionArea>
<placeName><region type="state">Californie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Akabas, Myles H" sort="Akabas, Myles H" uniqKey="Akabas M" first="Myles H" last="Akabas">Myles H. Akabas</name>
<affiliation wicri:level="2"><nlm:affiliation>Departments of Physiology & Biophysics, Neuroscience and Medicine, Albert Einstein College of Medicine, New York, New York, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Departments of Physiology & Biophysics, Neuroscience and Medicine, Albert Einstein College of Medicine, New York, New York</wicri:regionArea>
<placeName><region type="state">État de New York</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Alano, Pietro" sort="Alano, Pietro" uniqKey="Alano P" first="Pietro" last="Alano">Pietro Alano</name>
<affiliation wicri:level="3"><nlm:affiliation>Dipartimento Malattie Infettive, Parassitarie ed Immunomediate Istituto Superiore di Sanità, Roma, Italia.</nlm:affiliation>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Dipartimento Malattie Infettive, Parassitarie ed Immunomediate Istituto Superiore di Sanità, Roma</wicri:regionArea>
<placeName><settlement type="city">Rome</settlement>
<region nuts="2">Latium</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Alday, Aintzane" sort="Alday, Aintzane" uniqKey="Alday A" first="Aintzane" last="Alday">Aintzane Alday</name>
<affiliation wicri:level="1"><nlm:affiliation>BBD BioPhenix SL-BIOBIDE, Donostia, Gipuzkoa, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>BBD BioPhenix SL-BIOBIDE, Donostia, Gipuzkoa</wicri:regionArea>
<wicri:noRegion>Gipuzkoa</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Aleman Resto, Yesmalie" sort="Aleman Resto, Yesmalie" uniqKey="Aleman Resto Y" first="Yesmalie" last="Alemán Resto">Yesmalie Alemán Resto</name>
<affiliation wicri:level="2"><nlm:affiliation>Bigelow Laboratory for Ocean Sciences, East Boothbay, Maine, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Bigelow Laboratory for Ocean Sciences, East Boothbay, Maine</wicri:regionArea>
<placeName><region type="state">Maine (État)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Alsibaee, Aishah" sort="Alsibaee, Aishah" uniqKey="Alsibaee A" first="Aishah" last="Alsibaee">Aishah Alsibaee</name>
<affiliation wicri:level="1"><nlm:affiliation>Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland, Dublin, Ireland.</nlm:affiliation>
<country xml:lang="fr">Irlande (pays)</country>
<wicri:regionArea>Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland, Dublin</wicri:regionArea>
<wicri:noRegion>Dublin</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Alzualde, Ainhoa" sort="Alzualde, Ainhoa" uniqKey="Alzualde A" first="Ainhoa" last="Alzualde">Ainhoa Alzualde</name>
<affiliation wicri:level="1"><nlm:affiliation>BBD BioPhenix SL-BIOBIDE, Donostia, Gipuzkoa, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>BBD BioPhenix SL-BIOBIDE, Donostia, Gipuzkoa</wicri:regionArea>
<wicri:noRegion>Gipuzkoa</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Andrews, Katherine T" sort="Andrews, Katherine T" uniqKey="Andrews K" first="Katherine T" last="Andrews">Katherine T. Andrews</name>
<affiliation wicri:level="1"><nlm:affiliation>Eskitis Institute for Drug Discovery, Griffith University, Nathan, QLD, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Eskitis Institute for Drug Discovery, Griffith University, Nathan, QLD</wicri:regionArea>
<wicri:noRegion>QLD</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Avery, Simon V" sort="Avery, Simon V" uniqKey="Avery S" first="Simon V" last="Avery">Simon V. Avery</name>
<affiliation wicri:level="4"><nlm:affiliation>School of Life Sciences, University of Nottingham, Nottingham, Nottinghamshire, England, United Kingdom.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>School of Life Sciences, University of Nottingham, Nottingham, Nottinghamshire, England</wicri:regionArea>
<orgName type="university">Université de Nottingham</orgName>
<placeName><settlement type="city">Nottingham</settlement>
<region type="nation">Angleterre</region>
<region type="région" nuts="1">Nottinghamshire</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Avery, Vicky M" sort="Avery, Vicky M" uniqKey="Avery V" first="Vicky M" last="Avery">Vicky M. Avery</name>
<affiliation wicri:level="1"><nlm:affiliation>Eskitis Institute for Drug Discovery, Griffith University, Nathan, QLD, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Eskitis Institute for Drug Discovery, Griffith University, Nathan, QLD</wicri:regionArea>
<wicri:noRegion>QLD</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Ayong, Lawrence" sort="Ayong, Lawrence" uniqKey="Ayong L" first="Lawrence" last="Ayong">Lawrence Ayong</name>
<affiliation wicri:level="1"><nlm:affiliation>Institut Pasteur Korea, Pangyo Techno-Valley, Gyeonggi Province, Korea.</nlm:affiliation>
<country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea>Institut Pasteur Korea, Pangyo Techno-Valley, Gyeonggi Province</wicri:regionArea>
<wicri:noRegion>Gyeonggi Province</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Baker, Mark" sort="Baker, Mark" uniqKey="Baker M" first="Mark" last="Baker">Mark Baker</name>
<affiliation wicri:level="1"><nlm:affiliation>Clinical Pharmacology, Novartis Consumer Health, Nyon, Switzerland.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Clinical Pharmacology, Novartis Consumer Health, Nyon</wicri:regionArea>
<wicri:noRegion>Nyon</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Baker, Stephen" sort="Baker, Stephen" uniqKey="Baker S" first="Stephen" last="Baker">Stephen Baker</name>
<affiliation wicri:level="1"><nlm:affiliation>Oxford University Clinical Research Unit, Wellcome Trust Major Overseas Programme, The Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam.</nlm:affiliation>
<country xml:lang="fr">Viêt Nam</country>
<wicri:regionArea>Oxford University Clinical Research Unit, Wellcome Trust Major Overseas Programme, The Hospital for Tropical Diseases, Ho Chi Minh City</wicri:regionArea>
<wicri:noRegion>Ho Chi Minh City</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Ben Mamoun, Choukri" sort="Ben Mamoun, Choukri" uniqKey="Ben Mamoun C" first="Choukri" last="Ben Mamoun">Choukri Ben Mamoun</name>
<affiliation wicri:level="2"><nlm:affiliation>Internal Medicine, Yale University, New Haven, Connecticut, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Internal Medicine, Yale University, New Haven, Connecticut</wicri:regionArea>
<placeName><region type="state">Connecticut</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Bhatia, Sangeeta" sort="Bhatia, Sangeeta" uniqKey="Bhatia S" first="Sangeeta" last="Bhatia">Sangeeta Bhatia</name>
<affiliation wicri:level="2"><nlm:affiliation>Health Sciences and Technology/Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Health Sciences and Technology/Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, Massachusetts</wicri:regionArea>
<placeName><region type="state">Massachusetts</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Bickle, Quentin" sort="Bickle, Quentin" uniqKey="Bickle Q" first="Quentin" last="Bickle">Quentin Bickle</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Immunology & Infection, London School of Hygiene and Tropical Medicine, London, England, United Kingdom.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Immunology & Infection, London School of Hygiene and Tropical Medicine, London, England</wicri:regionArea>
<wicri:noRegion>England</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Bounaadja, Lotfi" sort="Bounaadja, Lotfi" uniqKey="Bounaadja L" first="Lotfi" last="Bounaadja">Lotfi Bounaadja</name>
<affiliation wicri:level="1"><nlm:affiliation>Museum of National History, Sorbonne Universities, Paris, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Museum of National History, Sorbonne Universities, Paris</wicri:regionArea>
<placeName><settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Bowling, Tana" sort="Bowling, Tana" uniqKey="Bowling T" first="Tana" last="Bowling">Tana Bowling</name>
<affiliation wicri:level="2"><nlm:affiliation>SCYNEXIS, Inc., Durham, North Carolina, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>SCYNEXIS, Inc., Durham, North Carolina</wicri:regionArea>
<placeName><region type="state">Caroline du Nord</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Bosch, Jurgen" sort="Bosch, Jurgen" uniqKey="Bosch J" first="Jürgen" last="Bosch">Jürgen Bosch</name>
<affiliation><nlm:affiliation>Department of Biochemistry and Molecular Biology and Johns Hopkins Malaria Research Institute, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, Untied States of America.</nlm:affiliation>
<wicri:noCountry code="subField">Untied States of America</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Boucher, Lauren E" sort="Boucher, Lauren E" uniqKey="Boucher L" first="Lauren E" last="Boucher">Lauren E. Boucher</name>
<affiliation><nlm:affiliation>Department of Biochemistry and Molecular Biology and Johns Hopkins Malaria Research Institute, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, Untied States of America.</nlm:affiliation>
<wicri:noCountry code="subField">Untied States of America</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Boyom, Fabrice F" sort="Boyom, Fabrice F" uniqKey="Boyom F" first="Fabrice F" last="Boyom">Fabrice F. Boyom</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Biochemistry, University of Yaoundé, Yaoundé, Cameroon.</nlm:affiliation>
<country xml:lang="fr">Cameroun</country>
<wicri:regionArea>Department of Biochemistry, University of Yaoundé, Yaoundé</wicri:regionArea>
<wicri:noRegion>Yaoundé</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Brea, Jose" sort="Brea, Jose" uniqKey="Brea J" first="Jose" last="Brea">Jose Brea</name>
<affiliation wicri:level="4"><nlm:affiliation>CIMUS Research Centre, University of Santiago de Compostela, Santiago de Compostela, A Coruña, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>CIMUS Research Centre, University of Santiago de Compostela, Santiago de Compostela, A Coruña</wicri:regionArea>
<orgName type="university">Université de Saint-Jacques-de-Compostelle</orgName>
<placeName><settlement type="city">Santiago de Compostela</settlement>
<region nuts="2" type="region">Galice</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Brennan, Marian" sort="Brennan, Marian" uniqKey="Brennan M" first="Marian" last="Brennan">Marian Brennan</name>
<affiliation wicri:level="1"><nlm:affiliation>Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland, Dublin, Ireland.</nlm:affiliation>
<country xml:lang="fr">Irlande (pays)</country>
<wicri:regionArea>Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland, Dublin</wicri:regionArea>
<wicri:noRegion>Dublin</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Burton, Audrey" sort="Burton, Audrey" uniqKey="Burton A" first="Audrey" last="Burton">Audrey Burton</name>
<affiliation wicri:level="2"><nlm:affiliation>SCYNEXIS, Inc., Durham, North Carolina, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>SCYNEXIS, Inc., Durham, North Carolina</wicri:regionArea>
<placeName><region type="state">Caroline du Nord</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Caffrey, Conor R" sort="Caffrey, Conor R" uniqKey="Caffrey C" first="Conor R" last="Caffrey">Conor R. Caffrey</name>
<affiliation wicri:level="2"><nlm:affiliation>Center for Discovery and Innovation in Parasitic Diseases, Department of Pathology, University of California San Francisco, San Francisco, California, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Center for Discovery and Innovation in Parasitic Diseases, Department of Pathology, University of California San Francisco, San Francisco, California</wicri:regionArea>
<placeName><region type="state">Californie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Camarda, Grazia" sort="Camarda, Grazia" uniqKey="Camarda G" first="Grazia" last="Camarda">Grazia Camarda</name>
<affiliation wicri:level="3"><nlm:affiliation>Dipartimento Malattie Infettive, Parassitarie ed Immunomediate Istituto Superiore di Sanità, Roma, Italia.</nlm:affiliation>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Dipartimento Malattie Infettive, Parassitarie ed Immunomediate Istituto Superiore di Sanità, Roma</wicri:regionArea>
<placeName><settlement type="city">Rome</settlement>
<region nuts="2">Latium</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Carrasquilla, Manuela" sort="Carrasquilla, Manuela" uniqKey="Carrasquilla M" first="Manuela" last="Carrasquilla">Manuela Carrasquilla</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Biochemistry and Molecular Biology and Huck Center for Malaria Research, Pennsylvania State University, University Park, Pennsylvania, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Biochemistry and Molecular Biology and Huck Center for Malaria Research, Pennsylvania State University, University Park, Pennsylvania</wicri:regionArea>
<placeName><region type="state">Pennsylvanie</region>
<settlement type="city">University Park (Pennsylvanie)</settlement>
</placeName>
<orgName type="university">Université d'État de Pennsylvanie</orgName>
</affiliation>
</author>
<author><name sortKey="Carter, Dee" sort="Carter, Dee" uniqKey="Carter D" first="Dee" last="Carter">Dee Carter</name>
<affiliation wicri:level="1"><nlm:affiliation>School of Life and Environmental Sciences, University of Sydney, Darlington New South Wales, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>School of Life and Environmental Sciences, University of Sydney, Darlington New South Wales</wicri:regionArea>
<wicri:noRegion>Darlington New South Wales</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Belen Cassera, Maria" sort="Belen Cassera, Maria" uniqKey="Belen Cassera M" first="Maria" last="Belen Cassera">Maria Belen Cassera</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Biochemistry and Virginia Tech Center for Drug Discovery, Virginia Polytechnic Institute and State University, Blacksburg, Virginia, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Biochemistry and Virginia Tech Center for Drug Discovery, Virginia Polytechnic Institute and State University, Blacksburg, Virginia</wicri:regionArea>
<placeName><region type="state">Virginie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Chih Chien Cheng, Ken" sort="Chih Chien Cheng, Ken" uniqKey="Chih Chien Cheng K" first="Ken" last="Chih-Chien Cheng">Ken Chih-Chien Cheng</name>
<affiliation wicri:level="2"><nlm:affiliation>National Center of Advancing Translational Sciences, NIH, Bethesda, Maryland, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>National Center of Advancing Translational Sciences, NIH, Bethesda, Maryland</wicri:regionArea>
<placeName><region type="state">Maryland</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Chindaudomsate, Worathad" sort="Chindaudomsate, Worathad" uniqKey="Chindaudomsate W" first="Worathad" last="Chindaudomsate">Worathad Chindaudomsate</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Biochemistry, Mahidol University, Bangkok, Thailand.</nlm:affiliation>
<country xml:lang="fr">Thaïlande</country>
<wicri:regionArea>Department of Biochemistry, Mahidol University, Bangkok</wicri:regionArea>
<wicri:noRegion>Bangkok</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Chubb, Anthony" sort="Chubb, Anthony" uniqKey="Chubb A" first="Anthony" last="Chubb">Anthony Chubb</name>
<affiliation wicri:level="1"><nlm:affiliation>Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland, Dublin, Ireland.</nlm:affiliation>
<country xml:lang="fr">Irlande (pays)</country>
<wicri:regionArea>Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland, Dublin</wicri:regionArea>
<wicri:noRegion>Dublin</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Colon, Beatrice L" sort="Colon, Beatrice L" uniqKey="Colon B" first="Beatrice L" last="Colon">Beatrice L. Colon</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Molecular Medicine, Morsani College of Medicine, University of South Florida, Tampa, Florida, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Molecular Medicine, Morsani College of Medicine, University of South Florida, Tampa, Florida</wicri:regionArea>
<placeName><region type="state">Floride</region>
<settlement type="city">Tampa</settlement>
</placeName>
<orgName type="university">Université de Floride du Sud</orgName>
</affiliation>
</author>
<author><name sortKey="Col N L Pez, Daisy D" sort="Col N L Pez, Daisy D" uniqKey="Col N L Pez D" first="Daisy D" last="Col N-L Pez">Daisy D. Col N-L Pez</name>
<affiliation><nlm:affiliation>Department of Biochemistry and Molecular Biology and Johns Hopkins Malaria Research Institute, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, Untied States of America.</nlm:affiliation>
<wicri:noCountry code="subField">Untied States of America</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Corbett, Yolanda" sort="Corbett, Yolanda" uniqKey="Corbett Y" first="Yolanda" last="Corbett">Yolanda Corbett</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Pharmacological and Biomolecular Sciences, Università degli Studi di Milano, Milano, Italy.</nlm:affiliation>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Department of Pharmacological and Biomolecular Sciences, Università degli Studi di Milano, Milano</wicri:regionArea>
<wicri:noRegion>Milano</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Crowther, Gregory J" sort="Crowther, Gregory J" uniqKey="Crowther G" first="Gregory J" last="Crowther">Gregory J. Crowther</name>
<affiliation wicri:level="4"><nlm:affiliation>Departments of Medicine, Microbiology, and Global Health, Center for Emerging and Re-emerging Infectious Diseases (CERID) University of Washington, Seattle, Washington, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Departments of Medicine, Microbiology, and Global Health, Center for Emerging and Re-emerging Infectious Diseases (CERID) University of Washington, Seattle, Washington</wicri:regionArea>
<placeName><region type="state">Washington (État)</region>
<settlement type="city">Seattle</settlement>
</placeName>
<orgName type="university">Université de Washington</orgName>
</affiliation>
</author>
<author><name sortKey="Cowan, Noemi" sort="Cowan, Noemi" uniqKey="Cowan N" first="Noemi" last="Cowan">Noemi Cowan</name>
<affiliation wicri:level="1"><nlm:affiliation>Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Basel, Switzerland.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Basel</wicri:regionArea>
<wicri:noRegion>Basel</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="D Alessandro, Sarah" sort="D Alessandro, Sarah" uniqKey="D Alessandro S" first="Sarah" last="D'Alessandro">Sarah D'Alessandro</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Pharmacological and Biomolecular Sciences, Università degli Studi di Milano, Milano, Italy.</nlm:affiliation>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Department of Pharmacological and Biomolecular Sciences, Università degli Studi di Milano, Milano</wicri:regionArea>
<wicri:noRegion>Milano</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Le Dang, Na" sort="Le Dang, Na" uniqKey="Le Dang N" first="Na" last="Le Dang">Na Le Dang</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Pathology and Immunology, Washington University in St Louis, St. Louis, Missouri, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Pathology and Immunology, Washington University in St Louis, St. Louis, Missouri</wicri:regionArea>
<placeName><region type="state">Missouri (État)</region>
<settlement type="city">Saint-Louis (Missouri)</settlement>
</placeName>
<orgName type="university">Université Washington de Saint-Louis</orgName>
</affiliation>
</author>
<author><name sortKey="Delves, Michael" sort="Delves, Michael" uniqKey="Delves M" first="Michael" last="Delves">Michael Delves</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Life Sciences, Imperial College London, London, England, United Kingdom.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Life Sciences, Imperial College London, London, England</wicri:regionArea>
<wicri:noRegion>England</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Derisi, Joseph L" sort="Derisi, Joseph L" uniqKey="Derisi J" first="Joseph L" last="Derisi">Joseph L. Derisi</name>
<affiliation wicri:level="2"><nlm:affiliation>Howard Hughes Medical Institute, Department of Biochemistry and Biophysics, University of California, San Francisco, California, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Howard Hughes Medical Institute, Department of Biochemistry and Biophysics, University of California, San Francisco, California</wicri:regionArea>
<placeName><region type="state">Californie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Du, Alan Y" sort="Du, Alan Y" uniqKey="Du A" first="Alan Y" last="Du">Alan Y. Du</name>
<affiliation wicri:level="2"><nlm:affiliation>Division of Pharmacology and Drug Discovery, Department of Pediatrics, School of Medicine University of California San Diego, La Jolla, California, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Division of Pharmacology and Drug Discovery, Department of Pediatrics, School of Medicine University of California San Diego, La Jolla, California</wicri:regionArea>
<placeName><region type="state">Californie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Duffy, Sandra" sort="Duffy, Sandra" uniqKey="Duffy S" first="Sandra" last="Duffy">Sandra Duffy</name>
<affiliation wicri:level="1"><nlm:affiliation>Eskitis Institute for Drug Discovery, Griffith University, Nathan, QLD, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Eskitis Institute for Drug Discovery, Griffith University, Nathan, QLD</wicri:regionArea>
<wicri:noRegion>QLD</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Abd El Salam El Sayed, Shimaa" sort="Abd El Salam El Sayed, Shimaa" uniqKey="Abd El Salam El Sayed S" first="Shimaa" last="Abd El-Salam El-Sayed">Shimaa Abd El-Salam El-Sayed</name>
<affiliation wicri:level="1"><nlm:affiliation>National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, Japan.</nlm:affiliation>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido</wicri:regionArea>
<wicri:noRegion>Hokkaido</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Ferdig, Michael T" sort="Ferdig, Michael T" uniqKey="Ferdig M" first="Michael T" last="Ferdig">Michael T. Ferdig</name>
<affiliation wicri:level="1"><nlm:affiliation>Eck Institute for Global Health, Department of Biological Sciences, University of Notre Dame, Notre Dame Indiana, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Eck Institute for Global Health, Department of Biological Sciences, University of Notre Dame, Notre Dame Indiana</wicri:regionArea>
<wicri:noRegion>Notre Dame Indiana</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Fernandez Robledo, Jose A" sort="Fernandez Robledo, Jose A" uniqKey="Fernandez Robledo J" first="José A" last="Fernández Robledo">José A. Fernández Robledo</name>
<affiliation wicri:level="2"><nlm:affiliation>Bigelow Laboratory for Ocean Sciences, East Boothbay, Maine, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Bigelow Laboratory for Ocean Sciences, East Boothbay, Maine</wicri:regionArea>
<placeName><region type="state">Maine (État)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Fidock, David A" sort="Fidock, David A" uniqKey="Fidock D" first="David A" last="Fidock">David A. Fidock</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Microbiology & Immunology and Division of Infectious Diseases, Department of Medicine, Columbia University Medical Center, New York, New York, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Microbiology & Immunology and Division of Infectious Diseases, Department of Medicine, Columbia University Medical Center, New York, New York</wicri:regionArea>
<placeName><region type="state">État de New York</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Florent, Isabelle" sort="Florent, Isabelle" uniqKey="Florent I" first="Isabelle" last="Florent">Isabelle Florent</name>
<affiliation wicri:level="1"><nlm:affiliation>Museum of National History, Sorbonne Universities, Paris, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Museum of National History, Sorbonne Universities, Paris</wicri:regionArea>
<placeName><settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Fokou, Patrick V T" sort="Fokou, Patrick V T" uniqKey="Fokou P" first="Patrick V T" last="Fokou">Patrick V T. Fokou</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Biochemistry, University of Yaoundé, Yaoundé, Cameroon.</nlm:affiliation>
<country xml:lang="fr">Cameroun</country>
<wicri:regionArea>Department of Biochemistry, University of Yaoundé, Yaoundé</wicri:regionArea>
<wicri:noRegion>Yaoundé</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Galstian, Ani" sort="Galstian, Ani" uniqKey="Galstian A" first="Ani" last="Galstian">Ani Galstian</name>
<affiliation wicri:level="2"><nlm:affiliation>Broad Institute, Cambridge, Massachusetts, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Broad Institute, Cambridge, Massachusetts</wicri:regionArea>
<placeName><region type="state">Massachusetts</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Gamo, Francisco Javier" sort="Gamo, Francisco Javier" uniqKey="Gamo F" first="Francisco Javier" last="Gamo">Francisco Javier Gamo</name>
<affiliation wicri:level="3"><nlm:affiliation>Biochemistry and Parasitology Department, Malaria DPU, Diseases of the Developing World (DDW), GlaxoSmithKline R&D, Tres Cantos, Madrid, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Biochemistry and Parasitology Department, Malaria DPU, Diseases of the Developing World (DDW), GlaxoSmithKline R&D, Tres Cantos, Madrid</wicri:regionArea>
<placeName><settlement type="city">Madrid</settlement>
<region nuts="2" type="region">Communauté de Madrid</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Gokool, Suzanne" sort="Gokool, Suzanne" uniqKey="Gokool S" first="Suzanne" last="Gokool">Suzanne Gokool</name>
<affiliation wicri:level="1"><nlm:affiliation>Tropical Parasitic Diseases Unit, Northwick Park Institute for Medical Research, Harrow, Middlesex, England, United Kingdom.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Tropical Parasitic Diseases Unit, Northwick Park Institute for Medical Research, Harrow, Middlesex, England</wicri:regionArea>
<wicri:noRegion>England</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Gold, Ben" sort="Gold, Ben" uniqKey="Gold B" first="Ben" last="Gold">Ben Gold</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Microbiology and Immunology, Weill Cornell Medical College, New York, New York, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Microbiology and Immunology, Weill Cornell Medical College, New York, New York</wicri:regionArea>
<placeName><region type="state">État de New York</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Golub, Todd" sort="Golub, Todd" uniqKey="Golub T" first="Todd" last="Golub">Todd Golub</name>
<affiliation wicri:level="2"><nlm:affiliation>Broad Institute, Cambridge, Massachusetts, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Broad Institute, Cambridge, Massachusetts</wicri:regionArea>
<placeName><region type="state">Massachusetts</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Goldgof, Gregory M" sort="Goldgof, Gregory M" uniqKey="Goldgof G" first="Gregory M" last="Goldgof">Gregory M. Goldgof</name>
<affiliation wicri:level="2"><nlm:affiliation>Medical Scientist Training Program, University of California, San Diego, San Diego, California, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Medical Scientist Training Program, University of California, San Diego, San Diego, California</wicri:regionArea>
<placeName><region type="state">Californie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Guha, Rajarshi" sort="Guha, Rajarshi" uniqKey="Guha R" first="Rajarshi" last="Guha">Rajarshi Guha</name>
<affiliation wicri:level="2"><nlm:affiliation>National Center of Advancing Translational Sciences, NIH, Bethesda, Maryland, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>National Center of Advancing Translational Sciences, NIH, Bethesda, Maryland</wicri:regionArea>
<placeName><region type="state">Maryland</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Guiguemde, W Armand" sort="Guiguemde, W Armand" uniqKey="Guiguemde W" first="W Armand" last="Guiguemde">W Armand Guiguemde</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Chemical Biology & Therapeutics, St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Chemical Biology & Therapeutics, St. Jude Children's Research Hospital, Memphis, Tennessee</wicri:regionArea>
<placeName><region type="state">Tennessee</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Gural, Nil" sort="Gural, Nil" uniqKey="Gural N" first="Nil" last="Gural">Nil Gural</name>
<affiliation wicri:level="2"><nlm:affiliation>Health Sciences and Technology/Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Health Sciences and Technology/Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, Massachusetts</wicri:regionArea>
<placeName><region type="state">Massachusetts</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Guy, R Kiplin" sort="Guy, R Kiplin" uniqKey="Guy R" first="R Kiplin" last="Guy">R Kiplin Guy</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Chemical Biology & Therapeutics, St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Chemical Biology & Therapeutics, St. Jude Children's Research Hospital, Memphis, Tennessee</wicri:regionArea>
<placeName><region type="state">Tennessee</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Hansen, Michael A E" sort="Hansen, Michael A E" uniqKey="Hansen M" first="Michael A E" last="Hansen">Michael A E. Hansen</name>
<affiliation wicri:level="1"><nlm:affiliation>Institut Pasteur Korea, Pangyo Techno-Valley, Gyeonggi Province, Korea.</nlm:affiliation>
<country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea>Institut Pasteur Korea, Pangyo Techno-Valley, Gyeonggi Province</wicri:regionArea>
<wicri:noRegion>Gyeonggi Province</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Hanson, Kirsten K" sort="Hanson, Kirsten K" uniqKey="Hanson K" first="Kirsten K" last="Hanson">Kirsten K. Hanson</name>
<affiliation wicri:level="2"><nlm:affiliation>Dept. of Biology and South Texas Center for Emerging Infectious Diseases, University of Texas, San Antonio, San Antonio, Texas, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Dept. of Biology and South Texas Center for Emerging Infectious Diseases, University of Texas, San Antonio, San Antonio, Texas</wicri:regionArea>
<placeName><region type="state">Texas</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Hemphill, Andrew" sort="Hemphill, Andrew" uniqKey="Hemphill A" first="Andrew" last="Hemphill">Andrew Hemphill</name>
<affiliation wicri:level="3"><nlm:affiliation>Institute of Parasitology, University of Berne, Bern, Switzerland.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Institute of Parasitology, University of Berne, Bern</wicri:regionArea>
<placeName><settlement type="city">Berne</settlement>
<region type="région" nuts="3">Canton de Berne</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Hooft Van Huijsduijnen, Rob" sort="Hooft Van Huijsduijnen, Rob" uniqKey="Hooft Van Huijsduijnen R" first="Rob" last="Hooft Van Huijsduijnen">Rob Hooft Van Huijsduijnen</name>
<affiliation wicri:level="1"><nlm:affiliation>Medicines for Malaria Venture, Geneva, Switzerland.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Medicines for Malaria Venture, Geneva</wicri:regionArea>
<wicri:noRegion>Geneva</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Horii, Takaaki" sort="Horii, Takaaki" uniqKey="Horii T" first="Takaaki" last="Horii">Takaaki Horii</name>
<affiliation wicri:level="1"><nlm:affiliation>Global Health Research Section, hhc Data Creation Center, Eisai Co., Ltd, Tsukuba-shi, Ibaraki, Japan.</nlm:affiliation>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Global Health Research Section, hhc Data Creation Center, Eisai Co., Ltd, Tsukuba-shi, Ibaraki</wicri:regionArea>
<wicri:noRegion>Ibaraki</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Horrocks, Paul" sort="Horrocks, Paul" uniqKey="Horrocks P" first="Paul" last="Horrocks">Paul Horrocks</name>
<affiliation wicri:level="1"><nlm:affiliation>Institute for Science and Technology in Medicine, Keele University, Keele, Staffordshire, United Kingdom.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Institute for Science and Technology in Medicine, Keele University, Keele, Staffordshire</wicri:regionArea>
<wicri:noRegion>Staffordshire</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Hughes, Tyler B" sort="Hughes, Tyler B" uniqKey="Hughes T" first="Tyler B" last="Hughes">Tyler B. Hughes</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Pathology and Immunology, Washington University in St Louis, St. Louis, Missouri, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Pathology and Immunology, Washington University in St Louis, St. Louis, Missouri</wicri:regionArea>
<placeName><region type="state">Missouri (État)</region>
<settlement type="city">Saint-Louis (Missouri)</settlement>
</placeName>
<orgName type="university">Université Washington de Saint-Louis</orgName>
</affiliation>
</author>
<author><name sortKey="Huston, Christopher" sort="Huston, Christopher" uniqKey="Huston C" first="Christopher" last="Huston">Christopher Huston</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Medicine, College of Medicine, University of Vermont, Burlington, Vermont, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Medicine, College of Medicine, University of Vermont, Burlington, Vermont</wicri:regionArea>
<placeName><region type="state">Vermont</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Igarashi, Ikuo" sort="Igarashi, Ikuo" uniqKey="Igarashi I" first="Ikuo" last="Igarashi">Ikuo Igarashi</name>
<affiliation wicri:level="1"><nlm:affiliation>National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, Japan.</nlm:affiliation>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido</wicri:regionArea>
<wicri:noRegion>Hokkaido</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Ingram Sieber, Katrin" sort="Ingram Sieber, Katrin" uniqKey="Ingram Sieber K" first="Katrin" last="Ingram-Sieber">Katrin Ingram-Sieber</name>
<affiliation wicri:level="1"><nlm:affiliation>Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Basel, Switzerland.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Basel</wicri:regionArea>
<wicri:noRegion>Basel</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Itoe, Maurice A" sort="Itoe, Maurice A" uniqKey="Itoe M" first="Maurice A" last="Itoe">Maurice A. Itoe</name>
<affiliation wicri:level="1"><nlm:affiliation>Instituto de Medicina Molecular, Lisboa, Portugal.</nlm:affiliation>
<country xml:lang="fr">Portugal</country>
<wicri:regionArea>Instituto de Medicina Molecular, Lisboa</wicri:regionArea>
<wicri:noRegion>Lisboa</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Jadhav, Ajit" sort="Jadhav, Ajit" uniqKey="Jadhav A" first="Ajit" last="Jadhav">Ajit Jadhav</name>
<affiliation wicri:level="2"><nlm:affiliation>National Center of Advancing Translational Sciences, NIH, Bethesda, Maryland, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>National Center of Advancing Translational Sciences, NIH, Bethesda, Maryland</wicri:regionArea>
<placeName><region type="state">Maryland</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Naranuntarat Jensen, Amornrat" sort="Naranuntarat Jensen, Amornrat" uniqKey="Naranuntarat Jensen A" first="Amornrat" last="Naranuntarat Jensen">Amornrat Naranuntarat Jensen</name>
<affiliation><nlm:affiliation>Department of Pathobiology, Faculty of Science, Mahidol University, Bangkok Thailand.</nlm:affiliation>
<wicri:noCountry code="subField">Bangkok Thailand</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Jensen, Laran T" sort="Jensen, Laran T" uniqKey="Jensen L" first="Laran T" last="Jensen">Laran T. Jensen</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Biochemistry, Mahidol University, Bangkok, Thailand.</nlm:affiliation>
<country xml:lang="fr">Thaïlande</country>
<wicri:regionArea>Department of Biochemistry, Mahidol University, Bangkok</wicri:regionArea>
<wicri:noRegion>Bangkok</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Jiang, Rays H Y" sort="Jiang, Rays H Y" uniqKey="Jiang R" first="Rays H Y" last="Jiang">Rays H Y. Jiang</name>
<affiliation wicri:level="4"><nlm:affiliation>Center for Global Health and Infectious Diseases Research, Department of Global Health, University of South Florida, Tampa, Florida, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Center for Global Health and Infectious Diseases Research, Department of Global Health, University of South Florida, Tampa, Florida</wicri:regionArea>
<placeName><region type="state">Floride</region>
<settlement type="city">Tampa</settlement>
</placeName>
<orgName type="university">Université de Floride du Sud</orgName>
</affiliation>
</author>
<author><name sortKey="Kaiser, Annette" sort="Kaiser, Annette" uniqKey="Kaiser A" first="Annette" last="Kaiser">Annette Kaiser</name>
<affiliation wicri:level="1"><nlm:affiliation>Medical Research Centre, Institute for Pharmacogenetics, Essen, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Medical Research Centre, Institute for Pharmacogenetics, Essen</wicri:regionArea>
<wicri:noRegion>Essen</wicri:noRegion>
<wicri:noRegion>Essen</wicri:noRegion>
<wicri:noRegion>Essen</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Keiser, Jennifer" sort="Keiser, Jennifer" uniqKey="Keiser J" first="Jennifer" last="Keiser">Jennifer Keiser</name>
<affiliation wicri:level="1"><nlm:affiliation>Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Basel, Switzerland.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Basel</wicri:regionArea>
<wicri:noRegion>Basel</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Ketas, Thomas" sort="Ketas, Thomas" uniqKey="Ketas T" first="Thomas" last="Ketas">Thomas Ketas</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Microbiology and Immunology, Weill Cornell Medical College, New York, New York, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Microbiology and Immunology, Weill Cornell Medical College, New York, New York</wicri:regionArea>
<placeName><region type="state">État de New York</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Kicka, Sebastien" sort="Kicka, Sebastien" uniqKey="Kicka S" first="Sebastien" last="Kicka">Sebastien Kicka</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Biochemistry, University of Geneva, Geneva, Switzerland.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Department of Biochemistry, University of Geneva, Geneva</wicri:regionArea>
<orgName type="university">Université de Genève</orgName>
<placeName><settlement type="city">Genève</settlement>
<region nuts="3" type="region">Canton de Genève</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Kim, Sunyoung" sort="Kim, Sunyoung" uniqKey="Kim S" first="Sunyoung" last="Kim">Sunyoung Kim</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Biochemistry and Molecular Biology, LSU Health Sciences Center, New Orleans, Louisiana, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Biochemistry and Molecular Biology, LSU Health Sciences Center, New Orleans, Louisiana</wicri:regionArea>
<placeName><region type="state">Louisiane</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Kirk, Kiaran" sort="Kirk, Kiaran" uniqKey="Kirk K" first="Kiaran" last="Kirk">Kiaran Kirk</name>
<affiliation wicri:level="1"><nlm:affiliation>Research School of Biology, Australian National University, Canberra, Australian Capital Territory, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Research School of Biology, Australian National University, Canberra, Australian Capital Territory</wicri:regionArea>
<wicri:noRegion>Australian Capital Territory</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Kumar, Vidya P" sort="Kumar, Vidya P" uniqKey="Kumar V" first="Vidya P" last="Kumar">Vidya P. Kumar</name>
<affiliation wicri:level="2"><nlm:affiliation>Internal Medicine, Yale University, New Haven, Connecticut, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Internal Medicine, Yale University, New Haven, Connecticut</wicri:regionArea>
<placeName><region type="state">Connecticut</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Kyle, Dennis E" sort="Kyle, Dennis E" uniqKey="Kyle D" first="Dennis E" last="Kyle">Dennis E. Kyle</name>
<affiliation wicri:level="4"><nlm:affiliation>Center for Global Health and Infectious Diseases Research, Department of Global Health, University of South Florida, Tampa, Florida, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Center for Global Health and Infectious Diseases Research, Department of Global Health, University of South Florida, Tampa, Florida</wicri:regionArea>
<placeName><region type="state">Floride</region>
<settlement type="city">Tampa</settlement>
</placeName>
<orgName type="university">Université de Floride du Sud</orgName>
</affiliation>
</author>
<author><name sortKey="Lafuente, Maria Jose" sort="Lafuente, Maria Jose" uniqKey="Lafuente M" first="Maria Jose" last="Lafuente">Maria Jose Lafuente</name>
<affiliation wicri:level="3"><nlm:affiliation>Biochemistry and Parasitology Department, Malaria DPU, Diseases of the Developing World (DDW), GlaxoSmithKline R&D, Tres Cantos, Madrid, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Biochemistry and Parasitology Department, Malaria DPU, Diseases of the Developing World (DDW), GlaxoSmithKline R&D, Tres Cantos, Madrid</wicri:regionArea>
<placeName><settlement type="city">Madrid</settlement>
<region nuts="2" type="region">Communauté de Madrid</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Landfear, Scott" sort="Landfear, Scott" uniqKey="Landfear S" first="Scott" last="Landfear">Scott Landfear</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Molecular Microbiology & Immunology, Oregon Health & Science University, Portland, Oregon, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Molecular Microbiology & Immunology, Oregon Health & Science University, Portland, Oregon</wicri:regionArea>
<placeName><region type="state">Oregon</region>
<settlement type="city">Portland</settlement>
</placeName>
<orgName type="university">Université des sciences et de la médecine de l'Oregon</orgName>
</affiliation>
</author>
<author><name sortKey="Lee, Nathan" sort="Lee, Nathan" uniqKey="Lee N" first="Nathan" last="Lee">Nathan Lee</name>
<affiliation wicri:level="1"><nlm:affiliation>Medicines for Malaria Venture, Geneva, Switzerland.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Medicines for Malaria Venture, Geneva</wicri:regionArea>
<wicri:noRegion>Geneva</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Lee, Sukjun" sort="Lee, Sukjun" uniqKey="Lee S" first="Sukjun" last="Lee">Sukjun Lee</name>
<affiliation wicri:level="1"><nlm:affiliation>Institut Pasteur Korea, Pangyo Techno-Valley, Gyeonggi Province, Korea.</nlm:affiliation>
<country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea>Institut Pasteur Korea, Pangyo Techno-Valley, Gyeonggi Province</wicri:regionArea>
<wicri:noRegion>Gyeonggi Province</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Lehane, Adele M" sort="Lehane, Adele M" uniqKey="Lehane A" first="Adele M" last="Lehane">Adele M. Lehane</name>
<affiliation wicri:level="1"><nlm:affiliation>Research School of Biology, Australian National University, Canberra, Australian Capital Territory, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Research School of Biology, Australian National University, Canberra, Australian Capital Territory</wicri:regionArea>
<wicri:noRegion>Australian Capital Territory</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Li, Fengwu" sort="Li, Fengwu" uniqKey="Li F" first="Fengwu" last="Li">Fengwu Li</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Molecular Microbiology & Immunology, Oregon Health & Science University, Portland, Oregon, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Molecular Microbiology & Immunology, Oregon Health & Science University, Portland, Oregon</wicri:regionArea>
<placeName><region type="state">Oregon</region>
<settlement type="city">Portland</settlement>
</placeName>
<orgName type="university">Université des sciences et de la médecine de l'Oregon</orgName>
</affiliation>
</author>
<author><name sortKey="Little, David" sort="Little, David" uniqKey="Little D" first="David" last="Little">David Little</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Microbiology and Immunology, Weill Cornell Medical College, New York, New York, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Microbiology and Immunology, Weill Cornell Medical College, New York, New York</wicri:regionArea>
<placeName><region type="state">État de New York</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Liu, Liqiong" sort="Liu, Liqiong" uniqKey="Liu L" first="Liqiong" last="Liu">Liqiong Liu</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Biochemistry and Molecular Biology, LSU Health Sciences Center, New Orleans, Louisiana, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Biochemistry and Molecular Biology, LSU Health Sciences Center, New Orleans, Louisiana</wicri:regionArea>
<placeName><region type="state">Louisiane</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Llinas, Manuel" sort="Llinas, Manuel" uniqKey="Llinas M" first="Manuel" last="Llinás">Manuel Llinás</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Biochemistry and Molecular Biology and Huck Center for Malaria Research, Pennsylvania State University, University Park, Pennsylvania, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Biochemistry and Molecular Biology and Huck Center for Malaria Research, Pennsylvania State University, University Park, Pennsylvania</wicri:regionArea>
<placeName><region type="state">Pennsylvanie</region>
<settlement type="city">University Park (Pennsylvanie)</settlement>
</placeName>
<orgName type="university">Université d'État de Pennsylvanie</orgName>
</affiliation>
</author>
<author><name sortKey="Loza, Maria I" sort="Loza, Maria I" uniqKey="Loza M" first="Maria I" last="Loza">Maria I. Loza</name>
<affiliation wicri:level="4"><nlm:affiliation>CIMUS Research Centre, University of Santiago de Compostela, Santiago de Compostela, A Coruña, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>CIMUS Research Centre, University of Santiago de Compostela, Santiago de Compostela, A Coruña</wicri:regionArea>
<orgName type="university">Université de Saint-Jacques-de-Compostelle</orgName>
<placeName><settlement type="city">Santiago de Compostela</settlement>
<region nuts="2" type="region">Galice</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Lubar, Aristea" sort="Lubar, Aristea" uniqKey="Lubar A" first="Aristea" last="Lubar">Aristea Lubar</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Medicine, University of California San Diego, San Diego, California, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Medicine, University of California San Diego, San Diego, California</wicri:regionArea>
<placeName><region type="state">Californie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Lucantoni, Leonardo" sort="Lucantoni, Leonardo" uniqKey="Lucantoni L" first="Leonardo" last="Lucantoni">Leonardo Lucantoni</name>
<affiliation wicri:level="1"><nlm:affiliation>Eskitis Institute for Drug Discovery, Griffith University, Nathan, QLD, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Eskitis Institute for Drug Discovery, Griffith University, Nathan, QLD</wicri:regionArea>
<wicri:noRegion>QLD</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Lucet, Isabelle" sort="Lucet, Isabelle" uniqKey="Lucet I" first="Isabelle" last="Lucet">Isabelle Lucet</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Biochemistry and Molecular Biology, Monash University, Clayton, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Department of Biochemistry and Molecular Biology, Monash University, Clayton</wicri:regionArea>
<wicri:noRegion>Clayton</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Maes, Louis" sort="Maes, Louis" uniqKey="Maes L" first="Louis" last="Maes">Louis Maes</name>
<affiliation wicri:level="4"><nlm:affiliation>University of Antwerp, Department of Biomedical Sciences, Antwerp, Belgium.</nlm:affiliation>
<country xml:lang="fr">Belgique</country>
<wicri:regionArea>University of Antwerp, Department of Biomedical Sciences, Antwerp</wicri:regionArea>
<orgName type="university">Université d'Anvers</orgName>
<placeName><settlement type="city">Anvers</settlement>
<region type="district" nuts="2">Province d'Anvers</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Mancama, Dalu" sort="Mancama, Dalu" uniqKey="Mancama D" first="Dalu" last="Mancama">Dalu Mancama</name>
<affiliation wicri:level="1"><nlm:affiliation>Biosciences Unit, Council for Scientific and Industrial Research, Pretoria, South Africa.</nlm:affiliation>
<country xml:lang="fr">Afrique du Sud</country>
<wicri:regionArea>Biosciences Unit, Council for Scientific and Industrial Research, Pretoria</wicri:regionArea>
<wicri:noRegion>Pretoria</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Mansour, Nuha R" sort="Mansour, Nuha R" uniqKey="Mansour N" first="Nuha R" last="Mansour">Nuha R. Mansour</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Immunology & Infection, London School of Hygiene and Tropical Medicine, London, England, United Kingdom.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Immunology & Infection, London School of Hygiene and Tropical Medicine, London, England</wicri:regionArea>
<wicri:noRegion>England</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="March, Sandra" sort="March, Sandra" uniqKey="March S" first="Sandra" last="March">Sandra March</name>
<affiliation wicri:level="2"><nlm:affiliation>Health Sciences and Technology/Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Health Sciences and Technology/Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, Massachusetts</wicri:regionArea>
<placeName><region type="state">Massachusetts</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Mcgowan, Sheena" sort="Mcgowan, Sheena" uniqKey="Mcgowan S" first="Sheena" last="Mcgowan">Sheena Mcgowan</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Microbiology, Monash University, Clayton, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Department of Microbiology, Monash University, Clayton</wicri:regionArea>
<wicri:noRegion>Clayton</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Medina Vera, Iset" sort="Medina Vera, Iset" uniqKey="Medina Vera I" first="Iset" last="Medina Vera">Iset Medina Vera</name>
<affiliation wicri:level="1"><nlm:affiliation>Instituto de Medicina Molecular, Lisboa, Portugal.</nlm:affiliation>
<country xml:lang="fr">Portugal</country>
<wicri:regionArea>Instituto de Medicina Molecular, Lisboa</wicri:regionArea>
<wicri:noRegion>Lisboa</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Meister, Stephan" sort="Meister, Stephan" uniqKey="Meister S" first="Stephan" last="Meister">Stephan Meister</name>
<affiliation wicri:level="2"><nlm:affiliation>Division of Pharmacology and Drug Discovery, Department of Pediatrics, School of Medicine University of California San Diego, La Jolla, California, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Division of Pharmacology and Drug Discovery, Department of Pediatrics, School of Medicine University of California San Diego, La Jolla, California</wicri:regionArea>
<placeName><region type="state">Californie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Mercer, Luke" sort="Mercer, Luke" uniqKey="Mercer L" first="Luke" last="Mercer">Luke Mercer</name>
<affiliation wicri:level="2"><nlm:affiliation>SCYNEXIS, Inc., Durham, North Carolina, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>SCYNEXIS, Inc., Durham, North Carolina</wicri:regionArea>
<placeName><region type="state">Caroline du Nord</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Mestres, Jordi" sort="Mestres, Jordi" uniqKey="Mestres J" first="Jordi" last="Mestres">Jordi Mestres</name>
<affiliation wicri:level="1"><nlm:affiliation>Chemotargets S.L. and Research Group on Systems Pharmacology, Research Program on Biomedical Informatics (GRIB), IMIM Hospital del Mar Institute of Medical Research and University Pompeu Fabra, Barcelona, Catalonia, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Chemotargets S.L. and Research Group on Systems Pharmacology, Research Program on Biomedical Informatics (GRIB), IMIM Hospital del Mar Institute of Medical Research and University Pompeu Fabra, Barcelona, Catalonia</wicri:regionArea>
<wicri:noRegion>Catalonia</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Mfopa, Alvine N" sort="Mfopa, Alvine N" uniqKey="Mfopa A" first="Alvine N" last="Mfopa">Alvine N. Mfopa</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Biochemistry, University of Yaoundé, Yaoundé, Cameroon.</nlm:affiliation>
<country xml:lang="fr">Cameroun</country>
<wicri:regionArea>Department of Biochemistry, University of Yaoundé, Yaoundé</wicri:regionArea>
<wicri:noRegion>Yaoundé</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Misra, Raj N" sort="Misra, Raj N" uniqKey="Misra R" first="Raj N" last="Misra">Raj N. Misra</name>
<affiliation wicri:level="2"><nlm:affiliation>Division of Cancer Therapeutics and Diagnosis, Drug Synthesis and Chemistry Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Division of Cancer Therapeutics and Diagnosis, Drug Synthesis and Chemistry Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland</wicri:regionArea>
<placeName><region type="state">Maryland</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Moon, Seunghyun" sort="Moon, Seunghyun" uniqKey="Moon S" first="Seunghyun" last="Moon">Seunghyun Moon</name>
<affiliation wicri:level="1"><nlm:affiliation>Institut Pasteur Korea, Pangyo Techno-Valley, Gyeonggi Province, Korea.</nlm:affiliation>
<country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea>Institut Pasteur Korea, Pangyo Techno-Valley, Gyeonggi Province</wicri:regionArea>
<wicri:noRegion>Gyeonggi Province</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Moore, John P" sort="Moore, John P" uniqKey="Moore J" first="John P" last="Moore">John P. Moore</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Microbiology and Immunology, Weill Cornell Medical College, New York, New York, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Microbiology and Immunology, Weill Cornell Medical College, New York, New York</wicri:regionArea>
<placeName><region type="state">État de New York</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Morais Rodrigues Da Costa, Francielly" sort="Morais Rodrigues Da Costa, Francielly" uniqKey="Morais Rodrigues Da Costa F" first="Francielly" last="Morais Rodrigues Da Costa">Francielly Morais Rodrigues Da Costa</name>
<affiliation wicri:level="4"><nlm:affiliation>Graduate Program in Bioinformatics, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.</nlm:affiliation>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Graduate Program in Bioinformatics, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais</wicri:regionArea>
<placeName><region type="state">Minas Gerais</region>
<settlement type="city">Belo Horizonte</settlement>
</placeName>
<orgName type="university">Université fédérale du Minas Gerais</orgName>
</affiliation>
</author>
<author><name sortKey="Muller, Joachim" sort="Muller, Joachim" uniqKey="Muller J" first="Joachim" last="Müller">Joachim Müller</name>
<affiliation wicri:level="3"><nlm:affiliation>Institute of Parasitology, University of Berne, Bern, Switzerland.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Institute of Parasitology, University of Berne, Bern</wicri:regionArea>
<placeName><settlement type="city">Berne</settlement>
<region type="région" nuts="3">Canton de Berne</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Muriana, Arantza" sort="Muriana, Arantza" uniqKey="Muriana A" first="Arantza" last="Muriana">Arantza Muriana</name>
<affiliation wicri:level="1"><nlm:affiliation>BBD BioPhenix SL-BIOBIDE, Donostia, Gipuzkoa, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>BBD BioPhenix SL-BIOBIDE, Donostia, Gipuzkoa</wicri:regionArea>
<wicri:noRegion>Gipuzkoa</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Nakazawa Hewitt, Stephen" sort="Nakazawa Hewitt, Stephen" uniqKey="Nakazawa Hewitt S" first="Stephen" last="Nakazawa Hewitt">Stephen Nakazawa Hewitt</name>
<affiliation wicri:level="4"><nlm:affiliation>Departments of Medicine, Microbiology, and Global Health, Center for Emerging and Re-emerging Infectious Diseases (CERID) University of Washington, Seattle, Washington, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Departments of Medicine, Microbiology, and Global Health, Center for Emerging and Re-emerging Infectious Diseases (CERID) University of Washington, Seattle, Washington</wicri:regionArea>
<placeName><region type="state">Washington (État)</region>
<settlement type="city">Seattle</settlement>
</placeName>
<orgName type="university">Université de Washington</orgName>
</affiliation>
</author>
<author><name sortKey="Nare, Bakela" sort="Nare, Bakela" uniqKey="Nare B" first="Bakela" last="Nare">Bakela Nare</name>
<affiliation wicri:level="2"><nlm:affiliation>SCYNEXIS, Inc., Durham, North Carolina, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>SCYNEXIS, Inc., Durham, North Carolina</wicri:regionArea>
<placeName><region type="state">Caroline du Nord</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Nathan, Carl" sort="Nathan, Carl" uniqKey="Nathan C" first="Carl" last="Nathan">Carl Nathan</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Microbiology and Immunology, Weill Cornell Medical College, New York, New York, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Microbiology and Immunology, Weill Cornell Medical College, New York, New York</wicri:regionArea>
<placeName><region type="state">État de New York</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Narraidoo, Nathalie" sort="Narraidoo, Nathalie" uniqKey="Narraidoo N" first="Nathalie" last="Narraidoo">Nathalie Narraidoo</name>
<affiliation wicri:level="4"><nlm:affiliation>School of Life Sciences, University of Nottingham, Nottingham, Nottinghamshire, England, United Kingdom.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>School of Life Sciences, University of Nottingham, Nottingham, Nottinghamshire, England</wicri:regionArea>
<orgName type="university">Université de Nottingham</orgName>
<placeName><settlement type="city">Nottingham</settlement>
<region type="nation">Angleterre</region>
<region type="région" nuts="1">Nottinghamshire</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Nawaratna, Sujeevi" sort="Nawaratna, Sujeevi" uniqKey="Nawaratna S" first="Sujeevi" last="Nawaratna">Sujeevi Nawaratna</name>
<affiliation wicri:level="1"><nlm:affiliation>Eskitis Institute for Drug Discovery, Griffith University, Nathan, QLD, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Eskitis Institute for Drug Discovery, Griffith University, Nathan, QLD</wicri:regionArea>
<wicri:noRegion>QLD</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Ojo, Kayode K" sort="Ojo, Kayode K" uniqKey="Ojo K" first="Kayode K" last="Ojo">Kayode K. Ojo</name>
<affiliation wicri:level="4"><nlm:affiliation>Departments of Medicine, Microbiology, and Global Health, Center for Emerging and Re-emerging Infectious Diseases (CERID) University of Washington, Seattle, Washington, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Departments of Medicine, Microbiology, and Global Health, Center for Emerging and Re-emerging Infectious Diseases (CERID) University of Washington, Seattle, Washington</wicri:regionArea>
<placeName><region type="state">Washington (État)</region>
<settlement type="city">Seattle</settlement>
</placeName>
<orgName type="university">Université de Washington</orgName>
</affiliation>
</author>
<author><name sortKey="Ortiz, Diana" sort="Ortiz, Diana" uniqKey="Ortiz D" first="Diana" last="Ortiz">Diana Ortiz</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Molecular Microbiology & Immunology, Oregon Health & Science University, Portland, Oregon, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Molecular Microbiology & Immunology, Oregon Health & Science University, Portland, Oregon</wicri:regionArea>
<placeName><region type="state">Oregon</region>
<settlement type="city">Portland</settlement>
</placeName>
<orgName type="university">Université des sciences et de la médecine de l'Oregon</orgName>
</affiliation>
</author>
<author><name sortKey="Panic, Gordana" sort="Panic, Gordana" uniqKey="Panic G" first="Gordana" last="Panic">Gordana Panic</name>
<affiliation wicri:level="1"><nlm:affiliation>Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Basel, Switzerland.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Basel</wicri:regionArea>
<wicri:noRegion>Basel</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Papadatos, George" sort="Papadatos, George" uniqKey="Papadatos G" first="George" last="Papadatos">George Papadatos</name>
<affiliation wicri:level="1"><nlm:affiliation>ChEMBL group, European Molecular Biology Laboratory-European Bioinformatics Institute (EMBL-EBI), Hinxton, Cambridgeshire, United Kingdom.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>ChEMBL group, European Molecular Biology Laboratory-European Bioinformatics Institute (EMBL-EBI), Hinxton, Cambridgeshire</wicri:regionArea>
<wicri:noRegion>Cambridgeshire</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Parapini, Silvia" sort="Parapini, Silvia" uniqKey="Parapini S" first="Silvia" last="Parapini">Silvia Parapini</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Pharmacological and Biomolecular Sciences, Università degli Studi di Milano, Milano, Italy.</nlm:affiliation>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Department of Pharmacological and Biomolecular Sciences, Università degli Studi di Milano, Milano</wicri:regionArea>
<wicri:noRegion>Milano</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Patra, Kailash" sort="Patra, Kailash" uniqKey="Patra K" first="Kailash" last="Patra">Kailash Patra</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Medicine, University of California San Diego, San Diego, California, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Medicine, University of California San Diego, San Diego, California</wicri:regionArea>
<placeName><region type="state">Californie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Pham, Ngoc" sort="Pham, Ngoc" uniqKey="Pham N" first="Ngoc" last="Pham">Ngoc Pham</name>
<affiliation wicri:level="1"><nlm:affiliation>Eskitis Institute for Drug Discovery, Griffith University, Nathan, QLD, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Eskitis Institute for Drug Discovery, Griffith University, Nathan, QLD</wicri:regionArea>
<wicri:noRegion>QLD</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Prats, Sarah" sort="Prats, Sarah" uniqKey="Prats S" first="Sarah" last="Prats">Sarah Prats</name>
<affiliation wicri:level="3"><nlm:affiliation>Biochemistry and Parasitology Department, Malaria DPU, Diseases of the Developing World (DDW), GlaxoSmithKline R&D, Tres Cantos, Madrid, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Biochemistry and Parasitology Department, Malaria DPU, Diseases of the Developing World (DDW), GlaxoSmithKline R&D, Tres Cantos, Madrid</wicri:regionArea>
<placeName><settlement type="city">Madrid</settlement>
<region nuts="2" type="region">Communauté de Madrid</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Plouffe, David M" sort="Plouffe, David M" uniqKey="Plouffe D" first="David M" last="Plouffe">David M. Plouffe</name>
<affiliation wicri:level="2"><nlm:affiliation>Genomics Institute of the Novartis Research Foundation, San Diego, California, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Genomics Institute of the Novartis Research Foundation, San Diego, California</wicri:regionArea>
<placeName><region type="state">Californie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Poulsen, Sally Ann" sort="Poulsen, Sally Ann" uniqKey="Poulsen S" first="Sally-Ann" last="Poulsen">Sally-Ann Poulsen</name>
<affiliation wicri:level="1"><nlm:affiliation>Eskitis Institute for Drug Discovery, Griffith University, Nathan, QLD, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Eskitis Institute for Drug Discovery, Griffith University, Nathan, QLD</wicri:regionArea>
<wicri:noRegion>QLD</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Pradhan, Anupam" sort="Pradhan, Anupam" uniqKey="Pradhan A" first="Anupam" last="Pradhan">Anupam Pradhan</name>
<affiliation wicri:level="4"><nlm:affiliation>Center for Global Health and Infectious Diseases Research, Department of Global Health, University of South Florida, Tampa, Florida, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Center for Global Health and Infectious Diseases Research, Department of Global Health, University of South Florida, Tampa, Florida</wicri:regionArea>
<placeName><region type="state">Floride</region>
<settlement type="city">Tampa</settlement>
</placeName>
<orgName type="university">Université de Floride du Sud</orgName>
</affiliation>
</author>
<author><name sortKey="Quevedo, Celia" sort="Quevedo, Celia" uniqKey="Quevedo C" first="Celia" last="Quevedo">Celia Quevedo</name>
<affiliation wicri:level="1"><nlm:affiliation>BBD BioPhenix SL-BIOBIDE, Donostia, Gipuzkoa, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>BBD BioPhenix SL-BIOBIDE, Donostia, Gipuzkoa</wicri:regionArea>
<wicri:noRegion>Gipuzkoa</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Quinn, Ronald J" sort="Quinn, Ronald J" uniqKey="Quinn R" first="Ronald J" last="Quinn">Ronald J. Quinn</name>
<affiliation wicri:level="1"><nlm:affiliation>Eskitis Institute for Drug Discovery, Griffith University, Nathan, QLD, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Eskitis Institute for Drug Discovery, Griffith University, Nathan, QLD</wicri:regionArea>
<wicri:noRegion>QLD</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Rice, Christopher A" sort="Rice, Christopher A" uniqKey="Rice C" first="Christopher A" last="Rice">Christopher A. Rice</name>
<affiliation wicri:level="4"><nlm:affiliation>Center for Global Health and Infectious Diseases Research, Department of Global Health, University of South Florida, Tampa, Florida, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Center for Global Health and Infectious Diseases Research, Department of Global Health, University of South Florida, Tampa, Florida</wicri:regionArea>
<placeName><region type="state">Floride</region>
<settlement type="city">Tampa</settlement>
</placeName>
<orgName type="university">Université de Floride du Sud</orgName>
</affiliation>
</author>
<author><name sortKey="Abdo Rizk, Mohamed" sort="Abdo Rizk, Mohamed" uniqKey="Abdo Rizk M" first="Mohamed" last="Abdo Rizk">Mohamed Abdo Rizk</name>
<affiliation wicri:level="1"><nlm:affiliation>National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, Japan.</nlm:affiliation>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido</wicri:regionArea>
<wicri:noRegion>Hokkaido</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Ruecker, Andrea" sort="Ruecker, Andrea" uniqKey="Ruecker A" first="Andrea" last="Ruecker">Andrea Ruecker</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Life Sciences, Imperial College London, London, England, United Kingdom.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Life Sciences, Imperial College London, London, England</wicri:regionArea>
<wicri:noRegion>England</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="St Onge, Robert" sort="St Onge, Robert" uniqKey="St Onge R" first="Robert" last="St Onge">Robert St Onge</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Biochemistry and Stanford Genome Technology Center, Stanford University, Palo Alto, Calilfornia, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Biochemistry and Stanford Genome Technology Center, Stanford University, Palo Alto, Calilfornia</wicri:regionArea>
<wicri:noRegion>Calilfornia</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Salgado Ferreira, Rafaela" sort="Salgado Ferreira, Rafaela" uniqKey="Salgado Ferreira R" first="Rafaela" last="Salgado Ferreira">Rafaela Salgado Ferreira</name>
<affiliation wicri:level="4"><nlm:affiliation>Departamento de Bioquímica e Imunologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.</nlm:affiliation>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Departamento de Bioquímica e Imunologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais</wicri:regionArea>
<placeName><region type="state">Minas Gerais</region>
<settlement type="city">Belo Horizonte</settlement>
</placeName>
<orgName type="university">Université fédérale du Minas Gerais</orgName>
</affiliation>
</author>
<author><name sortKey="Samra, Jasmeet" sort="Samra, Jasmeet" uniqKey="Samra J" first="Jasmeet" last="Samra">Jasmeet Samra</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Biochemistry and Molecular Biology and Huck Center for Malaria Research, Pennsylvania State University, University Park, Pennsylvania, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Biochemistry and Molecular Biology and Huck Center for Malaria Research, Pennsylvania State University, University Park, Pennsylvania</wicri:regionArea>
<placeName><region type="state">Pennsylvanie</region>
<settlement type="city">University Park (Pennsylvanie)</settlement>
</placeName>
<orgName type="university">Université d'État de Pennsylvanie</orgName>
</affiliation>
</author>
<author><name sortKey="Robinett, Natalie G" sort="Robinett, Natalie G" uniqKey="Robinett N" first="Natalie G" last="Robinett">Natalie G. Robinett</name>
<affiliation><nlm:affiliation>Department of Biochemistry and Molecular Biology and Johns Hopkins Malaria Research Institute, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, Untied States of America.</nlm:affiliation>
<wicri:noCountry code="subField">Untied States of America</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Schlecht, Ulrich" sort="Schlecht, Ulrich" uniqKey="Schlecht U" first="Ulrich" last="Schlecht">Ulrich Schlecht</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Biochemistry and Stanford Genome Technology Center, Stanford University, Palo Alto, Calilfornia, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Biochemistry and Stanford Genome Technology Center, Stanford University, Palo Alto, Calilfornia</wicri:regionArea>
<wicri:noRegion>Calilfornia</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Schmitt, Marjorie" sort="Schmitt, Marjorie" uniqKey="Schmitt M" first="Marjorie" last="Schmitt">Marjorie Schmitt</name>
<affiliation wicri:level="1"><nlm:affiliation>Laboratoire de Chimie Moléculaire, CNRS,-UMR 7509, COB-IRJBD, Mulhouse Cedex, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Laboratoire de Chimie Moléculaire, CNRS,-UMR 7509, COB-IRJBD, Mulhouse Cedex</wicri:regionArea>
<wicri:noRegion>Mulhouse Cedex</wicri:noRegion>
<wicri:noRegion>Mulhouse Cedex</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Silva Villela, Filipe" sort="Silva Villela, Filipe" uniqKey="Silva Villela F" first="Filipe" last="Silva Villela">Filipe Silva Villela</name>
<affiliation wicri:level="4"><nlm:affiliation>Departamento de Bioquímica e Imunologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.</nlm:affiliation>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Departamento de Bioquímica e Imunologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais</wicri:regionArea>
<placeName><region type="state">Minas Gerais</region>
<settlement type="city">Belo Horizonte</settlement>
</placeName>
<orgName type="university">Université fédérale du Minas Gerais</orgName>
</affiliation>
</author>
<author><name sortKey="Silvestrini, Francesco" sort="Silvestrini, Francesco" uniqKey="Silvestrini F" first="Francesco" last="Silvestrini">Francesco Silvestrini</name>
<affiliation wicri:level="3"><nlm:affiliation>Dipartimento Malattie Infettive, Parassitarie ed Immunomediate Istituto Superiore di Sanità, Roma, Italia.</nlm:affiliation>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Dipartimento Malattie Infettive, Parassitarie ed Immunomediate Istituto Superiore di Sanità, Roma</wicri:regionArea>
<placeName><settlement type="city">Rome</settlement>
<region nuts="2">Latium</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Sinden, Robert" sort="Sinden, Robert" uniqKey="Sinden R" first="Robert" last="Sinden">Robert Sinden</name>
<affiliation wicri:level="4"><nlm:affiliation>The Jenner Institute, University of Oxford, Oxford, England, United Kingdom.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>The Jenner Institute, University of Oxford, Oxford, England</wicri:regionArea>
<orgName type="university">Université d'Oxford</orgName>
<placeName><settlement type="city">Oxford</settlement>
<region type="nation">Angleterre</region>
<region type="région" nuts="1">Oxfordshire</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Smith, Dennis A" sort="Smith, Dennis A" uniqKey="Smith D" first="Dennis A" last="Smith">Dennis A. Smith</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Chemistry, University of Capetown, Capetown, South Africa.</nlm:affiliation>
<country xml:lang="fr">Afrique du Sud</country>
<wicri:regionArea>Department of Chemistry, University of Capetown, Capetown</wicri:regionArea>
<wicri:noRegion>Capetown</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Soldati, Thierry" sort="Soldati, Thierry" uniqKey="Soldati T" first="Thierry" last="Soldati">Thierry Soldati</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Biochemistry, University of Geneva, Geneva, Switzerland.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Department of Biochemistry, University of Geneva, Geneva</wicri:regionArea>
<orgName type="university">Université de Genève</orgName>
<placeName><settlement type="city">Genève</settlement>
<region nuts="3" type="region">Canton de Genève</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Spitzmuller, Andreas" sort="Spitzmuller, Andreas" uniqKey="Spitzmuller A" first="Andreas" last="Spitzmüller">Andreas Spitzmüller</name>
<affiliation wicri:level="1"><nlm:affiliation>Chemotargets S.L. and Research Group on Systems Pharmacology, Research Program on Biomedical Informatics (GRIB), IMIM Hospital del Mar Institute of Medical Research and University Pompeu Fabra, Barcelona, Catalonia, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Chemotargets S.L. and Research Group on Systems Pharmacology, Research Program on Biomedical Informatics (GRIB), IMIM Hospital del Mar Institute of Medical Research and University Pompeu Fabra, Barcelona, Catalonia</wicri:regionArea>
<wicri:noRegion>Catalonia</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Stamm, Serge Maximilian" sort="Stamm, Serge Maximilian" uniqKey="Stamm S" first="Serge Maximilian" last="Stamm">Serge Maximilian Stamm</name>
<affiliation><nlm:affiliation>Department of Biochemistry and Molecular Biology and Johns Hopkins Malaria Research Institute, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, Untied States of America.</nlm:affiliation>
<wicri:noCountry code="subField">Untied States of America</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Sullivan, David J" sort="Sullivan, David J" uniqKey="Sullivan D" first="David J" last="Sullivan">David J. Sullivan</name>
<affiliation wicri:level="2"><nlm:affiliation>H. Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins School of Public Health, Baltimore, Maryland, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>H. Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins School of Public Health, Baltimore, Maryland</wicri:regionArea>
<placeName><region type="state">Maryland</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Sullivan, William" sort="Sullivan, William" uniqKey="Sullivan W" first="William" last="Sullivan">William Sullivan</name>
<affiliation wicri:level="2"><nlm:affiliation>Molecular, Cell and Developmental Biology, University of California, Santa Cruz, Santa Cruz, California, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Molecular, Cell and Developmental Biology, University of California, Santa Cruz, Santa Cruz, California</wicri:regionArea>
<placeName><region type="state">Californie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Suresh, Sundari" sort="Suresh, Sundari" uniqKey="Suresh S" first="Sundari" last="Suresh">Sundari Suresh</name>
<affiliation wicri:level="4"><nlm:affiliation>Departamento de Bioquímica e Imunologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.</nlm:affiliation>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Departamento de Bioquímica e Imunologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais</wicri:regionArea>
<placeName><region type="state">Minas Gerais</region>
<settlement type="city">Belo Horizonte</settlement>
</placeName>
<orgName type="university">Université fédérale du Minas Gerais</orgName>
</affiliation>
</author>
<author><name sortKey="Suzuki, Brian M" sort="Suzuki, Brian M" uniqKey="Suzuki B" first="Brian M" last="Suzuki">Brian M. Suzuki</name>
<affiliation wicri:level="2"><nlm:affiliation>Center for Discovery and Innovation in Parasitic Diseases, Department of Pathology, University of California San Francisco, San Francisco, California, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Center for Discovery and Innovation in Parasitic Diseases, Department of Pathology, University of California San Francisco, San Francisco, California</wicri:regionArea>
<placeName><region type="state">Californie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Suzuki, Yo" sort="Suzuki, Yo" uniqKey="Suzuki Y" first="Yo" last="Suzuki">Yo Suzuki</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Synthetic Biology and Bioenergy, J. Craig Venter Institute, La Jolla, California, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Synthetic Biology and Bioenergy, J. Craig Venter Institute, La Jolla, California</wicri:regionArea>
<placeName><region type="state">Californie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Swamidass, S Joshua" sort="Swamidass, S Joshua" uniqKey="Swamidass S" first="S Joshua" last="Swamidass">S Joshua Swamidass</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Life Sciences, Imperial College London, London, England, United Kingdom.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Life Sciences, Imperial College London, London, England</wicri:regionArea>
<wicri:noRegion>England</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Taramelli, Donatella" sort="Taramelli, Donatella" uniqKey="Taramelli D" first="Donatella" last="Taramelli">Donatella Taramelli</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Pathology and Immunology, Washington University in St Louis, St. Louis, Missouri, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Pathology and Immunology, Washington University in St Louis, St. Louis, Missouri</wicri:regionArea>
<placeName><region type="state">Missouri (État)</region>
<settlement type="city">Saint-Louis (Missouri)</settlement>
</placeName>
<orgName type="university">Université Washington de Saint-Louis</orgName>
</affiliation>
</author>
<author><name sortKey="Tchokouaha, Lauve R Y" sort="Tchokouaha, Lauve R Y" uniqKey="Tchokouaha L" first="Lauve R Y" last="Tchokouaha">Lauve R Y. Tchokouaha</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Biochemistry, University of Yaoundé, Yaoundé, Cameroon.</nlm:affiliation>
<country xml:lang="fr">Cameroun</country>
<wicri:regionArea>Department of Biochemistry, University of Yaoundé, Yaoundé</wicri:regionArea>
<wicri:noRegion>Yaoundé</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Theron, Anjo" sort="Theron, Anjo" uniqKey="Theron A" first="Anjo" last="Theron">Anjo Theron</name>
<affiliation wicri:level="1"><nlm:affiliation>Biosciences Unit, Council for Scientific and Industrial Research, Pretoria, South Africa.</nlm:affiliation>
<country xml:lang="fr">Afrique du Sud</country>
<wicri:regionArea>Biosciences Unit, Council for Scientific and Industrial Research, Pretoria</wicri:regionArea>
<wicri:noRegion>Pretoria</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Thomas, David" sort="Thomas, David" uniqKey="Thomas D" first="David" last="Thomas">David Thomas</name>
<affiliation wicri:level="2"><nlm:affiliation>Broad Institute, Cambridge, Massachusetts, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Broad Institute, Cambridge, Massachusetts</wicri:regionArea>
<placeName><region type="state">Massachusetts</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Tonissen, Kathryn F" sort="Tonissen, Kathryn F" uniqKey="Tonissen K" first="Kathryn F" last="Tonissen">Kathryn F. Tonissen</name>
<affiliation wicri:level="1"><nlm:affiliation>Eskitis Institute for Drug Discovery, Griffith University, Nathan, QLD, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Eskitis Institute for Drug Discovery, Griffith University, Nathan, QLD</wicri:regionArea>
<wicri:noRegion>QLD</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Townson, Simon" sort="Townson, Simon" uniqKey="Townson S" first="Simon" last="Townson">Simon Townson</name>
<affiliation wicri:level="1"><nlm:affiliation>Tropical Parasitic Diseases Unit, Northwick Park Institute for Medical Research, Harrow, Middlesex, England, United Kingdom.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Tropical Parasitic Diseases Unit, Northwick Park Institute for Medical Research, Harrow, Middlesex, England</wicri:regionArea>
<wicri:noRegion>England</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Tripathi, Abhai K" sort="Tripathi, Abhai K" uniqKey="Tripathi A" first="Abhai K" last="Tripathi">Abhai K. Tripathi</name>
<affiliation wicri:level="2"><nlm:affiliation>H. Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins School of Public Health, Baltimore, Maryland, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>H. Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins School of Public Health, Baltimore, Maryland</wicri:regionArea>
<placeName><region type="state">Maryland</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Trofimov, Valentin" sort="Trofimov, Valentin" uniqKey="Trofimov V" first="Valentin" last="Trofimov">Valentin Trofimov</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Biochemistry, University of Geneva, Geneva, Switzerland.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Department of Biochemistry, University of Geneva, Geneva</wicri:regionArea>
<orgName type="university">Université de Genève</orgName>
<placeName><settlement type="city">Genève</settlement>
<region nuts="3" type="region">Canton de Genève</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Udenze, Kenneth O" sort="Udenze, Kenneth O" uniqKey="Udenze K" first="Kenneth O" last="Udenze">Kenneth O. Udenze</name>
<affiliation wicri:level="4"><nlm:affiliation>Center for Global Health and Infectious Diseases Research, Department of Global Health, University of South Florida, Tampa, Florida, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Center for Global Health and Infectious Diseases Research, Department of Global Health, University of South Florida, Tampa, Florida</wicri:regionArea>
<placeName><region type="state">Floride</region>
<settlement type="city">Tampa</settlement>
</placeName>
<orgName type="university">Université de Floride du Sud</orgName>
</affiliation>
</author>
<author><name sortKey="Ullah, Imran" sort="Ullah, Imran" uniqKey="Ullah I" first="Imran" last="Ullah">Imran Ullah</name>
<affiliation wicri:level="1"><nlm:affiliation>Institute for Science and Technology in Medicine, Keele University, Keele, Staffordshire, United Kingdom.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Institute for Science and Technology in Medicine, Keele University, Keele, Staffordshire</wicri:regionArea>
<wicri:noRegion>Staffordshire</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Vallieres, Cindy" sort="Vallieres, Cindy" uniqKey="Vallieres C" first="Cindy" last="Vallieres">Cindy Vallieres</name>
<affiliation wicri:level="4"><nlm:affiliation>School of Life Sciences, University of Nottingham, Nottingham, Nottinghamshire, England, United Kingdom.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>School of Life Sciences, University of Nottingham, Nottingham, Nottinghamshire, England</wicri:regionArea>
<orgName type="university">Université de Nottingham</orgName>
<placeName><settlement type="city">Nottingham</settlement>
<region type="nation">Angleterre</region>
<region type="région" nuts="1">Nottinghamshire</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Vigil, Edgar" sort="Vigil, Edgar" uniqKey="Vigil E" first="Edgar" last="Vigil">Edgar Vigil</name>
<affiliation wicri:level="2"><nlm:affiliation>Division of Pharmacology and Drug Discovery, Department of Pediatrics, School of Medicine University of California San Diego, La Jolla, California, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Division of Pharmacology and Drug Discovery, Department of Pediatrics, School of Medicine University of California San Diego, La Jolla, California</wicri:regionArea>
<placeName><region type="state">Californie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Vinetz, Joseph M" sort="Vinetz, Joseph M" uniqKey="Vinetz J" first="Joseph M" last="Vinetz">Joseph M. Vinetz</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Medicine, University of California San Diego, San Diego, California, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Medicine, University of California San Diego, San Diego, California</wicri:regionArea>
<placeName><region type="state">Californie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Voong Vinh, Phat" sort="Voong Vinh, Phat" uniqKey="Voong Vinh P" first="Phat" last="Voong Vinh">Phat Voong Vinh</name>
<affiliation wicri:level="1"><nlm:affiliation>Oxford University Clinical Research Unit, Wellcome Trust Major Overseas Programme, The Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam.</nlm:affiliation>
<country xml:lang="fr">Viêt Nam</country>
<wicri:regionArea>Oxford University Clinical Research Unit, Wellcome Trust Major Overseas Programme, The Hospital for Tropical Diseases, Ho Chi Minh City</wicri:regionArea>
<wicri:noRegion>Ho Chi Minh City</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Vu, Hoan" sort="Vu, Hoan" uniqKey="Vu H" first="Hoan" last="Vu">Hoan Vu</name>
<affiliation wicri:level="1"><nlm:affiliation>Eskitis Institute for Drug Discovery, Griffith University, Nathan, QLD, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Eskitis Institute for Drug Discovery, Griffith University, Nathan, QLD</wicri:regionArea>
<wicri:noRegion>QLD</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Watanabe, Nao Aki" sort="Watanabe, Nao Aki" uniqKey="Watanabe N" first="Nao-Aki" last="Watanabe">Nao-Aki Watanabe</name>
<affiliation wicri:level="1"><nlm:affiliation>Global Health Research Section, hhc Data Creation Center, Eisai Co., Ltd, Tsukuba-shi, Ibaraki, Japan.</nlm:affiliation>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Global Health Research Section, hhc Data Creation Center, Eisai Co., Ltd, Tsukuba-shi, Ibaraki</wicri:regionArea>
<wicri:noRegion>Ibaraki</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Weatherby, Kate" sort="Weatherby, Kate" uniqKey="Weatherby K" first="Kate" last="Weatherby">Kate Weatherby</name>
<affiliation wicri:level="1"><nlm:affiliation>School of Life and Environmental Sciences, University of Sydney, Darlington New South Wales, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>School of Life and Environmental Sciences, University of Sydney, Darlington New South Wales</wicri:regionArea>
<wicri:noRegion>Darlington New South Wales</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="White, Pamela M" sort="White, Pamela M" uniqKey="White P" first="Pamela M" last="White">Pamela M. White</name>
<affiliation wicri:level="2"><nlm:affiliation>Molecular, Cell and Developmental Biology, University of California, Santa Cruz, Santa Cruz, California, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Molecular, Cell and Developmental Biology, University of California, Santa Cruz, Santa Cruz, California</wicri:regionArea>
<placeName><region type="state">Californie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Wilks, Andrew F" sort="Wilks, Andrew F" uniqKey="Wilks A" first="Andrew F" last="Wilks">Andrew F. Wilks</name>
<affiliation wicri:level="1"><nlm:affiliation>Hudson Institute of Medical Research; Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Hudson Institute of Medical Research; Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria</wicri:regionArea>
<wicri:noRegion>Victoria</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Winzeler, Elizabeth A" sort="Winzeler, Elizabeth A" uniqKey="Winzeler E" first="Elizabeth A" last="Winzeler">Elizabeth A. Winzeler</name>
<affiliation wicri:level="2"><nlm:affiliation>Division of Pharmacology and Drug Discovery, Department of Pediatrics, School of Medicine University of California San Diego, La Jolla, California, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Division of Pharmacology and Drug Discovery, Department of Pediatrics, School of Medicine University of California San Diego, La Jolla, California</wicri:regionArea>
<placeName><region type="state">Californie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Wojcik, Edward" sort="Wojcik, Edward" uniqKey="Wojcik E" first="Edward" last="Wojcik">Edward Wojcik</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Biochemistry and Molecular Biology, LSU Health Sciences Center, New Orleans, Louisiana, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Biochemistry and Molecular Biology, LSU Health Sciences Center, New Orleans, Louisiana</wicri:regionArea>
<placeName><region type="state">Louisiane</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Wree, Melanie" sort="Wree, Melanie" uniqKey="Wree M" first="Melanie" last="Wree">Melanie Wree</name>
<affiliation wicri:level="2"><nlm:affiliation>Division of Pharmacology and Drug Discovery, Department of Pediatrics, School of Medicine University of California San Diego, La Jolla, California, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Division of Pharmacology and Drug Discovery, Department of Pediatrics, School of Medicine University of California San Diego, La Jolla, California</wicri:regionArea>
<placeName><region type="state">Californie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Wu, Wesley" sort="Wu, Wesley" uniqKey="Wu W" first="Wesley" last="Wu">Wesley Wu</name>
<affiliation wicri:level="2"><nlm:affiliation>Howard Hughes Medical Institute, Department of Biochemistry and Biophysics, University of California, San Francisco, California, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Howard Hughes Medical Institute, Department of Biochemistry and Biophysics, University of California, San Francisco, California</wicri:regionArea>
<placeName><region type="state">Californie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Yokoyama, Naoaki" sort="Yokoyama, Naoaki" uniqKey="Yokoyama N" first="Naoaki" last="Yokoyama">Naoaki Yokoyama</name>
<affiliation wicri:level="1"><nlm:affiliation>National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, Japan.</nlm:affiliation>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido</wicri:regionArea>
<wicri:noRegion>Hokkaido</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Zollo, Paul H A" sort="Zollo, Paul H A" uniqKey="Zollo P" first="Paul H A" last="Zollo">Paul H A. Zollo</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Biochemistry, University of Yaoundé, Yaoundé, Cameroon.</nlm:affiliation>
<country xml:lang="fr">Cameroun</country>
<wicri:regionArea>Department of Biochemistry, University of Yaoundé, Yaoundé</wicri:regionArea>
<wicri:noRegion>Yaoundé</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Abla, Nada" sort="Abla, Nada" uniqKey="Abla N" first="Nada" last="Abla">Nada Abla</name>
<affiliation wicri:level="1"><nlm:affiliation>Medicines for Malaria Venture, Geneva, Switzerland.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Medicines for Malaria Venture, Geneva</wicri:regionArea>
<wicri:noRegion>Geneva</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Blasco, Benjamin" sort="Blasco, Benjamin" uniqKey="Blasco B" first="Benjamin" last="Blasco">Benjamin Blasco</name>
<affiliation wicri:level="1"><nlm:affiliation>Medicines for Malaria Venture, Geneva, Switzerland.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Medicines for Malaria Venture, Geneva</wicri:regionArea>
<wicri:noRegion>Geneva</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Burrows, Jeremy" sort="Burrows, Jeremy" uniqKey="Burrows J" first="Jeremy" last="Burrows">Jeremy Burrows</name>
<affiliation wicri:level="1"><nlm:affiliation>Medicines for Malaria Venture, Geneva, Switzerland.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Medicines for Malaria Venture, Geneva</wicri:regionArea>
<wicri:noRegion>Geneva</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Laleu, Benoit" sort="Laleu, Benoit" uniqKey="Laleu B" first="Benoît" last="Laleu">Benoît Laleu</name>
<affiliation wicri:level="1"><nlm:affiliation>Medicines for Malaria Venture, Geneva, Switzerland.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Medicines for Malaria Venture, Geneva</wicri:regionArea>
<wicri:noRegion>Geneva</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Leroy, Didier" sort="Leroy, Didier" uniqKey="Leroy D" first="Didier" last="Leroy">Didier Leroy</name>
<affiliation wicri:level="1"><nlm:affiliation>Medicines for Malaria Venture, Geneva, Switzerland.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Medicines for Malaria Venture, Geneva</wicri:regionArea>
<wicri:noRegion>Geneva</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Spangenberg, Thomas" sort="Spangenberg, Thomas" uniqKey="Spangenberg T" first="Thomas" last="Spangenberg">Thomas Spangenberg</name>
<affiliation wicri:level="1"><nlm:affiliation>Medicines for Malaria Venture, Geneva, Switzerland.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Medicines for Malaria Venture, Geneva</wicri:regionArea>
<wicri:noRegion>Geneva</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Wells, Timothy" sort="Wells, Timothy" uniqKey="Wells T" first="Timothy" last="Wells">Timothy Wells</name>
<affiliation wicri:level="1"><nlm:affiliation>Medicines for Malaria Venture, Geneva, Switzerland.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Medicines for Malaria Venture, Geneva</wicri:regionArea>
<wicri:noRegion>Geneva</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Willis, Paul A" sort="Willis, Paul A" uniqKey="Willis P" first="Paul A" last="Willis">Paul A. Willis</name>
<affiliation wicri:level="1"><nlm:affiliation>Medicines for Malaria Venture, Geneva, Switzerland.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Medicines for Malaria Venture, Geneva</wicri:regionArea>
<wicri:noRegion>Geneva</wicri:noRegion>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2016">2016</date>
<idno type="RBID">pubmed:27467575</idno>
<idno type="pmid">27467575</idno>
<idno type="doi">10.1371/journal.ppat.1005763</idno>
<idno type="wicri:Area/PubMed/Corpus">000008</idno>
<idno type="wicri:Area/PubMed/Curation">000008</idno>
<idno type="wicri:Area/PubMed/Checkpoint">000008</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.</title>
<author><name sortKey="Van Voorhis, Wesley C" sort="Van Voorhis, Wesley C" uniqKey="Van Voorhis W" first="Wesley C" last="Van Voorhis">Wesley C. Van Voorhis</name>
<affiliation wicri:level="4"><nlm:affiliation>Departments of Medicine, Microbiology, and Global Health, Center for Emerging and Re-emerging Infectious Diseases (CERID) University of Washington, Seattle, Washington, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Departments of Medicine, Microbiology, and Global Health, Center for Emerging and Re-emerging Infectious Diseases (CERID) University of Washington, Seattle, Washington</wicri:regionArea>
<placeName><region type="state">Washington (État)</region>
<settlement type="city">Seattle</settlement>
</placeName>
<orgName type="university">Université de Washington</orgName>
</affiliation>
</author>
<author><name sortKey="Adams, John H" sort="Adams, John H" uniqKey="Adams J" first="John H" last="Adams">John H. Adams</name>
<affiliation wicri:level="4"><nlm:affiliation>Center for Global Health and Infectious Diseases Research, Department of Global Health, University of South Florida, Tampa, Florida, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Center for Global Health and Infectious Diseases Research, Department of Global Health, University of South Florida, Tampa, Florida</wicri:regionArea>
<placeName><region type="state">Floride</region>
<settlement type="city">Tampa</settlement>
</placeName>
<orgName type="university">Université de Floride du Sud</orgName>
</affiliation>
</author>
<author><name sortKey="Adelfio, Roberto" sort="Adelfio, Roberto" uniqKey="Adelfio R" first="Roberto" last="Adelfio">Roberto Adelfio</name>
<affiliation wicri:level="1"><nlm:affiliation>Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Basel, Switzerland.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Basel</wicri:regionArea>
<wicri:noRegion>Basel</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Ahyong, Vida" sort="Ahyong, Vida" uniqKey="Ahyong V" first="Vida" last="Ahyong">Vida Ahyong</name>
<affiliation wicri:level="2"><nlm:affiliation>Howard Hughes Medical Institute, Department of Biochemistry and Biophysics, University of California, San Francisco, California, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Howard Hughes Medical Institute, Department of Biochemistry and Biophysics, University of California, San Francisco, California</wicri:regionArea>
<placeName><region type="state">Californie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Akabas, Myles H" sort="Akabas, Myles H" uniqKey="Akabas M" first="Myles H" last="Akabas">Myles H. Akabas</name>
<affiliation wicri:level="2"><nlm:affiliation>Departments of Physiology & Biophysics, Neuroscience and Medicine, Albert Einstein College of Medicine, New York, New York, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Departments of Physiology & Biophysics, Neuroscience and Medicine, Albert Einstein College of Medicine, New York, New York</wicri:regionArea>
<placeName><region type="state">État de New York</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Alano, Pietro" sort="Alano, Pietro" uniqKey="Alano P" first="Pietro" last="Alano">Pietro Alano</name>
<affiliation wicri:level="3"><nlm:affiliation>Dipartimento Malattie Infettive, Parassitarie ed Immunomediate Istituto Superiore di Sanità, Roma, Italia.</nlm:affiliation>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Dipartimento Malattie Infettive, Parassitarie ed Immunomediate Istituto Superiore di Sanità, Roma</wicri:regionArea>
<placeName><settlement type="city">Rome</settlement>
<region nuts="2">Latium</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Alday, Aintzane" sort="Alday, Aintzane" uniqKey="Alday A" first="Aintzane" last="Alday">Aintzane Alday</name>
<affiliation wicri:level="1"><nlm:affiliation>BBD BioPhenix SL-BIOBIDE, Donostia, Gipuzkoa, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>BBD BioPhenix SL-BIOBIDE, Donostia, Gipuzkoa</wicri:regionArea>
<wicri:noRegion>Gipuzkoa</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Aleman Resto, Yesmalie" sort="Aleman Resto, Yesmalie" uniqKey="Aleman Resto Y" first="Yesmalie" last="Alemán Resto">Yesmalie Alemán Resto</name>
<affiliation wicri:level="2"><nlm:affiliation>Bigelow Laboratory for Ocean Sciences, East Boothbay, Maine, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Bigelow Laboratory for Ocean Sciences, East Boothbay, Maine</wicri:regionArea>
<placeName><region type="state">Maine (État)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Alsibaee, Aishah" sort="Alsibaee, Aishah" uniqKey="Alsibaee A" first="Aishah" last="Alsibaee">Aishah Alsibaee</name>
<affiliation wicri:level="1"><nlm:affiliation>Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland, Dublin, Ireland.</nlm:affiliation>
<country xml:lang="fr">Irlande (pays)</country>
<wicri:regionArea>Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland, Dublin</wicri:regionArea>
<wicri:noRegion>Dublin</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Alzualde, Ainhoa" sort="Alzualde, Ainhoa" uniqKey="Alzualde A" first="Ainhoa" last="Alzualde">Ainhoa Alzualde</name>
<affiliation wicri:level="1"><nlm:affiliation>BBD BioPhenix SL-BIOBIDE, Donostia, Gipuzkoa, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>BBD BioPhenix SL-BIOBIDE, Donostia, Gipuzkoa</wicri:regionArea>
<wicri:noRegion>Gipuzkoa</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Andrews, Katherine T" sort="Andrews, Katherine T" uniqKey="Andrews K" first="Katherine T" last="Andrews">Katherine T. Andrews</name>
<affiliation wicri:level="1"><nlm:affiliation>Eskitis Institute for Drug Discovery, Griffith University, Nathan, QLD, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Eskitis Institute for Drug Discovery, Griffith University, Nathan, QLD</wicri:regionArea>
<wicri:noRegion>QLD</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Avery, Simon V" sort="Avery, Simon V" uniqKey="Avery S" first="Simon V" last="Avery">Simon V. Avery</name>
<affiliation wicri:level="4"><nlm:affiliation>School of Life Sciences, University of Nottingham, Nottingham, Nottinghamshire, England, United Kingdom.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>School of Life Sciences, University of Nottingham, Nottingham, Nottinghamshire, England</wicri:regionArea>
<orgName type="university">Université de Nottingham</orgName>
<placeName><settlement type="city">Nottingham</settlement>
<region type="nation">Angleterre</region>
<region type="région" nuts="1">Nottinghamshire</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Avery, Vicky M" sort="Avery, Vicky M" uniqKey="Avery V" first="Vicky M" last="Avery">Vicky M. Avery</name>
<affiliation wicri:level="1"><nlm:affiliation>Eskitis Institute for Drug Discovery, Griffith University, Nathan, QLD, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Eskitis Institute for Drug Discovery, Griffith University, Nathan, QLD</wicri:regionArea>
<wicri:noRegion>QLD</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Ayong, Lawrence" sort="Ayong, Lawrence" uniqKey="Ayong L" first="Lawrence" last="Ayong">Lawrence Ayong</name>
<affiliation wicri:level="1"><nlm:affiliation>Institut Pasteur Korea, Pangyo Techno-Valley, Gyeonggi Province, Korea.</nlm:affiliation>
<country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea>Institut Pasteur Korea, Pangyo Techno-Valley, Gyeonggi Province</wicri:regionArea>
<wicri:noRegion>Gyeonggi Province</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Baker, Mark" sort="Baker, Mark" uniqKey="Baker M" first="Mark" last="Baker">Mark Baker</name>
<affiliation wicri:level="1"><nlm:affiliation>Clinical Pharmacology, Novartis Consumer Health, Nyon, Switzerland.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Clinical Pharmacology, Novartis Consumer Health, Nyon</wicri:regionArea>
<wicri:noRegion>Nyon</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Baker, Stephen" sort="Baker, Stephen" uniqKey="Baker S" first="Stephen" last="Baker">Stephen Baker</name>
<affiliation wicri:level="1"><nlm:affiliation>Oxford University Clinical Research Unit, Wellcome Trust Major Overseas Programme, The Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam.</nlm:affiliation>
<country xml:lang="fr">Viêt Nam</country>
<wicri:regionArea>Oxford University Clinical Research Unit, Wellcome Trust Major Overseas Programme, The Hospital for Tropical Diseases, Ho Chi Minh City</wicri:regionArea>
<wicri:noRegion>Ho Chi Minh City</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Ben Mamoun, Choukri" sort="Ben Mamoun, Choukri" uniqKey="Ben Mamoun C" first="Choukri" last="Ben Mamoun">Choukri Ben Mamoun</name>
<affiliation wicri:level="2"><nlm:affiliation>Internal Medicine, Yale University, New Haven, Connecticut, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Internal Medicine, Yale University, New Haven, Connecticut</wicri:regionArea>
<placeName><region type="state">Connecticut</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Bhatia, Sangeeta" sort="Bhatia, Sangeeta" uniqKey="Bhatia S" first="Sangeeta" last="Bhatia">Sangeeta Bhatia</name>
<affiliation wicri:level="2"><nlm:affiliation>Health Sciences and Technology/Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Health Sciences and Technology/Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, Massachusetts</wicri:regionArea>
<placeName><region type="state">Massachusetts</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Bickle, Quentin" sort="Bickle, Quentin" uniqKey="Bickle Q" first="Quentin" last="Bickle">Quentin Bickle</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Immunology & Infection, London School of Hygiene and Tropical Medicine, London, England, United Kingdom.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Immunology & Infection, London School of Hygiene and Tropical Medicine, London, England</wicri:regionArea>
<wicri:noRegion>England</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Bounaadja, Lotfi" sort="Bounaadja, Lotfi" uniqKey="Bounaadja L" first="Lotfi" last="Bounaadja">Lotfi Bounaadja</name>
<affiliation wicri:level="1"><nlm:affiliation>Museum of National History, Sorbonne Universities, Paris, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Museum of National History, Sorbonne Universities, Paris</wicri:regionArea>
<placeName><settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Bowling, Tana" sort="Bowling, Tana" uniqKey="Bowling T" first="Tana" last="Bowling">Tana Bowling</name>
<affiliation wicri:level="2"><nlm:affiliation>SCYNEXIS, Inc., Durham, North Carolina, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>SCYNEXIS, Inc., Durham, North Carolina</wicri:regionArea>
<placeName><region type="state">Caroline du Nord</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Bosch, Jurgen" sort="Bosch, Jurgen" uniqKey="Bosch J" first="Jürgen" last="Bosch">Jürgen Bosch</name>
<affiliation><nlm:affiliation>Department of Biochemistry and Molecular Biology and Johns Hopkins Malaria Research Institute, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, Untied States of America.</nlm:affiliation>
<wicri:noCountry code="subField">Untied States of America</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Boucher, Lauren E" sort="Boucher, Lauren E" uniqKey="Boucher L" first="Lauren E" last="Boucher">Lauren E. Boucher</name>
<affiliation><nlm:affiliation>Department of Biochemistry and Molecular Biology and Johns Hopkins Malaria Research Institute, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, Untied States of America.</nlm:affiliation>
<wicri:noCountry code="subField">Untied States of America</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Boyom, Fabrice F" sort="Boyom, Fabrice F" uniqKey="Boyom F" first="Fabrice F" last="Boyom">Fabrice F. Boyom</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Biochemistry, University of Yaoundé, Yaoundé, Cameroon.</nlm:affiliation>
<country xml:lang="fr">Cameroun</country>
<wicri:regionArea>Department of Biochemistry, University of Yaoundé, Yaoundé</wicri:regionArea>
<wicri:noRegion>Yaoundé</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Brea, Jose" sort="Brea, Jose" uniqKey="Brea J" first="Jose" last="Brea">Jose Brea</name>
<affiliation wicri:level="4"><nlm:affiliation>CIMUS Research Centre, University of Santiago de Compostela, Santiago de Compostela, A Coruña, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>CIMUS Research Centre, University of Santiago de Compostela, Santiago de Compostela, A Coruña</wicri:regionArea>
<orgName type="university">Université de Saint-Jacques-de-Compostelle</orgName>
<placeName><settlement type="city">Santiago de Compostela</settlement>
<region nuts="2" type="region">Galice</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Brennan, Marian" sort="Brennan, Marian" uniqKey="Brennan M" first="Marian" last="Brennan">Marian Brennan</name>
<affiliation wicri:level="1"><nlm:affiliation>Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland, Dublin, Ireland.</nlm:affiliation>
<country xml:lang="fr">Irlande (pays)</country>
<wicri:regionArea>Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland, Dublin</wicri:regionArea>
<wicri:noRegion>Dublin</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Burton, Audrey" sort="Burton, Audrey" uniqKey="Burton A" first="Audrey" last="Burton">Audrey Burton</name>
<affiliation wicri:level="2"><nlm:affiliation>SCYNEXIS, Inc., Durham, North Carolina, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>SCYNEXIS, Inc., Durham, North Carolina</wicri:regionArea>
<placeName><region type="state">Caroline du Nord</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Caffrey, Conor R" sort="Caffrey, Conor R" uniqKey="Caffrey C" first="Conor R" last="Caffrey">Conor R. Caffrey</name>
<affiliation wicri:level="2"><nlm:affiliation>Center for Discovery and Innovation in Parasitic Diseases, Department of Pathology, University of California San Francisco, San Francisco, California, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Center for Discovery and Innovation in Parasitic Diseases, Department of Pathology, University of California San Francisco, San Francisco, California</wicri:regionArea>
<placeName><region type="state">Californie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Camarda, Grazia" sort="Camarda, Grazia" uniqKey="Camarda G" first="Grazia" last="Camarda">Grazia Camarda</name>
<affiliation wicri:level="3"><nlm:affiliation>Dipartimento Malattie Infettive, Parassitarie ed Immunomediate Istituto Superiore di Sanità, Roma, Italia.</nlm:affiliation>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Dipartimento Malattie Infettive, Parassitarie ed Immunomediate Istituto Superiore di Sanità, Roma</wicri:regionArea>
<placeName><settlement type="city">Rome</settlement>
<region nuts="2">Latium</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Carrasquilla, Manuela" sort="Carrasquilla, Manuela" uniqKey="Carrasquilla M" first="Manuela" last="Carrasquilla">Manuela Carrasquilla</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Biochemistry and Molecular Biology and Huck Center for Malaria Research, Pennsylvania State University, University Park, Pennsylvania, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Biochemistry and Molecular Biology and Huck Center for Malaria Research, Pennsylvania State University, University Park, Pennsylvania</wicri:regionArea>
<placeName><region type="state">Pennsylvanie</region>
<settlement type="city">University Park (Pennsylvanie)</settlement>
</placeName>
<orgName type="university">Université d'État de Pennsylvanie</orgName>
</affiliation>
</author>
<author><name sortKey="Carter, Dee" sort="Carter, Dee" uniqKey="Carter D" first="Dee" last="Carter">Dee Carter</name>
<affiliation wicri:level="1"><nlm:affiliation>School of Life and Environmental Sciences, University of Sydney, Darlington New South Wales, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>School of Life and Environmental Sciences, University of Sydney, Darlington New South Wales</wicri:regionArea>
<wicri:noRegion>Darlington New South Wales</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Belen Cassera, Maria" sort="Belen Cassera, Maria" uniqKey="Belen Cassera M" first="Maria" last="Belen Cassera">Maria Belen Cassera</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Biochemistry and Virginia Tech Center for Drug Discovery, Virginia Polytechnic Institute and State University, Blacksburg, Virginia, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Biochemistry and Virginia Tech Center for Drug Discovery, Virginia Polytechnic Institute and State University, Blacksburg, Virginia</wicri:regionArea>
<placeName><region type="state">Virginie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Chih Chien Cheng, Ken" sort="Chih Chien Cheng, Ken" uniqKey="Chih Chien Cheng K" first="Ken" last="Chih-Chien Cheng">Ken Chih-Chien Cheng</name>
<affiliation wicri:level="2"><nlm:affiliation>National Center of Advancing Translational Sciences, NIH, Bethesda, Maryland, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>National Center of Advancing Translational Sciences, NIH, Bethesda, Maryland</wicri:regionArea>
<placeName><region type="state">Maryland</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Chindaudomsate, Worathad" sort="Chindaudomsate, Worathad" uniqKey="Chindaudomsate W" first="Worathad" last="Chindaudomsate">Worathad Chindaudomsate</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Biochemistry, Mahidol University, Bangkok, Thailand.</nlm:affiliation>
<country xml:lang="fr">Thaïlande</country>
<wicri:regionArea>Department of Biochemistry, Mahidol University, Bangkok</wicri:regionArea>
<wicri:noRegion>Bangkok</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Chubb, Anthony" sort="Chubb, Anthony" uniqKey="Chubb A" first="Anthony" last="Chubb">Anthony Chubb</name>
<affiliation wicri:level="1"><nlm:affiliation>Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland, Dublin, Ireland.</nlm:affiliation>
<country xml:lang="fr">Irlande (pays)</country>
<wicri:regionArea>Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland, Dublin</wicri:regionArea>
<wicri:noRegion>Dublin</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Colon, Beatrice L" sort="Colon, Beatrice L" uniqKey="Colon B" first="Beatrice L" last="Colon">Beatrice L. Colon</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Molecular Medicine, Morsani College of Medicine, University of South Florida, Tampa, Florida, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Molecular Medicine, Morsani College of Medicine, University of South Florida, Tampa, Florida</wicri:regionArea>
<placeName><region type="state">Floride</region>
<settlement type="city">Tampa</settlement>
</placeName>
<orgName type="university">Université de Floride du Sud</orgName>
</affiliation>
</author>
<author><name sortKey="Col N L Pez, Daisy D" sort="Col N L Pez, Daisy D" uniqKey="Col N L Pez D" first="Daisy D" last="Col N-L Pez">Daisy D. Col N-L Pez</name>
<affiliation><nlm:affiliation>Department of Biochemistry and Molecular Biology and Johns Hopkins Malaria Research Institute, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, Untied States of America.</nlm:affiliation>
<wicri:noCountry code="subField">Untied States of America</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Corbett, Yolanda" sort="Corbett, Yolanda" uniqKey="Corbett Y" first="Yolanda" last="Corbett">Yolanda Corbett</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Pharmacological and Biomolecular Sciences, Università degli Studi di Milano, Milano, Italy.</nlm:affiliation>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Department of Pharmacological and Biomolecular Sciences, Università degli Studi di Milano, Milano</wicri:regionArea>
<wicri:noRegion>Milano</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Crowther, Gregory J" sort="Crowther, Gregory J" uniqKey="Crowther G" first="Gregory J" last="Crowther">Gregory J. Crowther</name>
<affiliation wicri:level="4"><nlm:affiliation>Departments of Medicine, Microbiology, and Global Health, Center for Emerging and Re-emerging Infectious Diseases (CERID) University of Washington, Seattle, Washington, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Departments of Medicine, Microbiology, and Global Health, Center for Emerging and Re-emerging Infectious Diseases (CERID) University of Washington, Seattle, Washington</wicri:regionArea>
<placeName><region type="state">Washington (État)</region>
<settlement type="city">Seattle</settlement>
</placeName>
<orgName type="university">Université de Washington</orgName>
</affiliation>
</author>
<author><name sortKey="Cowan, Noemi" sort="Cowan, Noemi" uniqKey="Cowan N" first="Noemi" last="Cowan">Noemi Cowan</name>
<affiliation wicri:level="1"><nlm:affiliation>Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Basel, Switzerland.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Basel</wicri:regionArea>
<wicri:noRegion>Basel</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="D Alessandro, Sarah" sort="D Alessandro, Sarah" uniqKey="D Alessandro S" first="Sarah" last="D'Alessandro">Sarah D'Alessandro</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Pharmacological and Biomolecular Sciences, Università degli Studi di Milano, Milano, Italy.</nlm:affiliation>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Department of Pharmacological and Biomolecular Sciences, Università degli Studi di Milano, Milano</wicri:regionArea>
<wicri:noRegion>Milano</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Le Dang, Na" sort="Le Dang, Na" uniqKey="Le Dang N" first="Na" last="Le Dang">Na Le Dang</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Pathology and Immunology, Washington University in St Louis, St. Louis, Missouri, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Pathology and Immunology, Washington University in St Louis, St. Louis, Missouri</wicri:regionArea>
<placeName><region type="state">Missouri (État)</region>
<settlement type="city">Saint-Louis (Missouri)</settlement>
</placeName>
<orgName type="university">Université Washington de Saint-Louis</orgName>
</affiliation>
</author>
<author><name sortKey="Delves, Michael" sort="Delves, Michael" uniqKey="Delves M" first="Michael" last="Delves">Michael Delves</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Life Sciences, Imperial College London, London, England, United Kingdom.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Life Sciences, Imperial College London, London, England</wicri:regionArea>
<wicri:noRegion>England</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Derisi, Joseph L" sort="Derisi, Joseph L" uniqKey="Derisi J" first="Joseph L" last="Derisi">Joseph L. Derisi</name>
<affiliation wicri:level="2"><nlm:affiliation>Howard Hughes Medical Institute, Department of Biochemistry and Biophysics, University of California, San Francisco, California, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Howard Hughes Medical Institute, Department of Biochemistry and Biophysics, University of California, San Francisco, California</wicri:regionArea>
<placeName><region type="state">Californie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Du, Alan Y" sort="Du, Alan Y" uniqKey="Du A" first="Alan Y" last="Du">Alan Y. Du</name>
<affiliation wicri:level="2"><nlm:affiliation>Division of Pharmacology and Drug Discovery, Department of Pediatrics, School of Medicine University of California San Diego, La Jolla, California, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Division of Pharmacology and Drug Discovery, Department of Pediatrics, School of Medicine University of California San Diego, La Jolla, California</wicri:regionArea>
<placeName><region type="state">Californie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Duffy, Sandra" sort="Duffy, Sandra" uniqKey="Duffy S" first="Sandra" last="Duffy">Sandra Duffy</name>
<affiliation wicri:level="1"><nlm:affiliation>Eskitis Institute for Drug Discovery, Griffith University, Nathan, QLD, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Eskitis Institute for Drug Discovery, Griffith University, Nathan, QLD</wicri:regionArea>
<wicri:noRegion>QLD</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Abd El Salam El Sayed, Shimaa" sort="Abd El Salam El Sayed, Shimaa" uniqKey="Abd El Salam El Sayed S" first="Shimaa" last="Abd El-Salam El-Sayed">Shimaa Abd El-Salam El-Sayed</name>
<affiliation wicri:level="1"><nlm:affiliation>National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, Japan.</nlm:affiliation>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido</wicri:regionArea>
<wicri:noRegion>Hokkaido</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Ferdig, Michael T" sort="Ferdig, Michael T" uniqKey="Ferdig M" first="Michael T" last="Ferdig">Michael T. Ferdig</name>
<affiliation wicri:level="1"><nlm:affiliation>Eck Institute for Global Health, Department of Biological Sciences, University of Notre Dame, Notre Dame Indiana, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Eck Institute for Global Health, Department of Biological Sciences, University of Notre Dame, Notre Dame Indiana</wicri:regionArea>
<wicri:noRegion>Notre Dame Indiana</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Fernandez Robledo, Jose A" sort="Fernandez Robledo, Jose A" uniqKey="Fernandez Robledo J" first="José A" last="Fernández Robledo">José A. Fernández Robledo</name>
<affiliation wicri:level="2"><nlm:affiliation>Bigelow Laboratory for Ocean Sciences, East Boothbay, Maine, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Bigelow Laboratory for Ocean Sciences, East Boothbay, Maine</wicri:regionArea>
<placeName><region type="state">Maine (État)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Fidock, David A" sort="Fidock, David A" uniqKey="Fidock D" first="David A" last="Fidock">David A. Fidock</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Microbiology & Immunology and Division of Infectious Diseases, Department of Medicine, Columbia University Medical Center, New York, New York, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Microbiology & Immunology and Division of Infectious Diseases, Department of Medicine, Columbia University Medical Center, New York, New York</wicri:regionArea>
<placeName><region type="state">État de New York</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Florent, Isabelle" sort="Florent, Isabelle" uniqKey="Florent I" first="Isabelle" last="Florent">Isabelle Florent</name>
<affiliation wicri:level="1"><nlm:affiliation>Museum of National History, Sorbonne Universities, Paris, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Museum of National History, Sorbonne Universities, Paris</wicri:regionArea>
<placeName><settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Fokou, Patrick V T" sort="Fokou, Patrick V T" uniqKey="Fokou P" first="Patrick V T" last="Fokou">Patrick V T. Fokou</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Biochemistry, University of Yaoundé, Yaoundé, Cameroon.</nlm:affiliation>
<country xml:lang="fr">Cameroun</country>
<wicri:regionArea>Department of Biochemistry, University of Yaoundé, Yaoundé</wicri:regionArea>
<wicri:noRegion>Yaoundé</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Galstian, Ani" sort="Galstian, Ani" uniqKey="Galstian A" first="Ani" last="Galstian">Ani Galstian</name>
<affiliation wicri:level="2"><nlm:affiliation>Broad Institute, Cambridge, Massachusetts, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Broad Institute, Cambridge, Massachusetts</wicri:regionArea>
<placeName><region type="state">Massachusetts</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Gamo, Francisco Javier" sort="Gamo, Francisco Javier" uniqKey="Gamo F" first="Francisco Javier" last="Gamo">Francisco Javier Gamo</name>
<affiliation wicri:level="3"><nlm:affiliation>Biochemistry and Parasitology Department, Malaria DPU, Diseases of the Developing World (DDW), GlaxoSmithKline R&D, Tres Cantos, Madrid, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Biochemistry and Parasitology Department, Malaria DPU, Diseases of the Developing World (DDW), GlaxoSmithKline R&D, Tres Cantos, Madrid</wicri:regionArea>
<placeName><settlement type="city">Madrid</settlement>
<region nuts="2" type="region">Communauté de Madrid</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Gokool, Suzanne" sort="Gokool, Suzanne" uniqKey="Gokool S" first="Suzanne" last="Gokool">Suzanne Gokool</name>
<affiliation wicri:level="1"><nlm:affiliation>Tropical Parasitic Diseases Unit, Northwick Park Institute for Medical Research, Harrow, Middlesex, England, United Kingdom.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Tropical Parasitic Diseases Unit, Northwick Park Institute for Medical Research, Harrow, Middlesex, England</wicri:regionArea>
<wicri:noRegion>England</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Gold, Ben" sort="Gold, Ben" uniqKey="Gold B" first="Ben" last="Gold">Ben Gold</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Microbiology and Immunology, Weill Cornell Medical College, New York, New York, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Microbiology and Immunology, Weill Cornell Medical College, New York, New York</wicri:regionArea>
<placeName><region type="state">État de New York</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Golub, Todd" sort="Golub, Todd" uniqKey="Golub T" first="Todd" last="Golub">Todd Golub</name>
<affiliation wicri:level="2"><nlm:affiliation>Broad Institute, Cambridge, Massachusetts, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Broad Institute, Cambridge, Massachusetts</wicri:regionArea>
<placeName><region type="state">Massachusetts</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Goldgof, Gregory M" sort="Goldgof, Gregory M" uniqKey="Goldgof G" first="Gregory M" last="Goldgof">Gregory M. Goldgof</name>
<affiliation wicri:level="2"><nlm:affiliation>Medical Scientist Training Program, University of California, San Diego, San Diego, California, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Medical Scientist Training Program, University of California, San Diego, San Diego, California</wicri:regionArea>
<placeName><region type="state">Californie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Guha, Rajarshi" sort="Guha, Rajarshi" uniqKey="Guha R" first="Rajarshi" last="Guha">Rajarshi Guha</name>
<affiliation wicri:level="2"><nlm:affiliation>National Center of Advancing Translational Sciences, NIH, Bethesda, Maryland, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>National Center of Advancing Translational Sciences, NIH, Bethesda, Maryland</wicri:regionArea>
<placeName><region type="state">Maryland</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Guiguemde, W Armand" sort="Guiguemde, W Armand" uniqKey="Guiguemde W" first="W Armand" last="Guiguemde">W Armand Guiguemde</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Chemical Biology & Therapeutics, St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Chemical Biology & Therapeutics, St. Jude Children's Research Hospital, Memphis, Tennessee</wicri:regionArea>
<placeName><region type="state">Tennessee</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Gural, Nil" sort="Gural, Nil" uniqKey="Gural N" first="Nil" last="Gural">Nil Gural</name>
<affiliation wicri:level="2"><nlm:affiliation>Health Sciences and Technology/Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Health Sciences and Technology/Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, Massachusetts</wicri:regionArea>
<placeName><region type="state">Massachusetts</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Guy, R Kiplin" sort="Guy, R Kiplin" uniqKey="Guy R" first="R Kiplin" last="Guy">R Kiplin Guy</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Chemical Biology & Therapeutics, St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Chemical Biology & Therapeutics, St. Jude Children's Research Hospital, Memphis, Tennessee</wicri:regionArea>
<placeName><region type="state">Tennessee</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Hansen, Michael A E" sort="Hansen, Michael A E" uniqKey="Hansen M" first="Michael A E" last="Hansen">Michael A E. Hansen</name>
<affiliation wicri:level="1"><nlm:affiliation>Institut Pasteur Korea, Pangyo Techno-Valley, Gyeonggi Province, Korea.</nlm:affiliation>
<country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea>Institut Pasteur Korea, Pangyo Techno-Valley, Gyeonggi Province</wicri:regionArea>
<wicri:noRegion>Gyeonggi Province</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Hanson, Kirsten K" sort="Hanson, Kirsten K" uniqKey="Hanson K" first="Kirsten K" last="Hanson">Kirsten K. Hanson</name>
<affiliation wicri:level="2"><nlm:affiliation>Dept. of Biology and South Texas Center for Emerging Infectious Diseases, University of Texas, San Antonio, San Antonio, Texas, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Dept. of Biology and South Texas Center for Emerging Infectious Diseases, University of Texas, San Antonio, San Antonio, Texas</wicri:regionArea>
<placeName><region type="state">Texas</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Hemphill, Andrew" sort="Hemphill, Andrew" uniqKey="Hemphill A" first="Andrew" last="Hemphill">Andrew Hemphill</name>
<affiliation wicri:level="3"><nlm:affiliation>Institute of Parasitology, University of Berne, Bern, Switzerland.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Institute of Parasitology, University of Berne, Bern</wicri:regionArea>
<placeName><settlement type="city">Berne</settlement>
<region type="région" nuts="3">Canton de Berne</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Hooft Van Huijsduijnen, Rob" sort="Hooft Van Huijsduijnen, Rob" uniqKey="Hooft Van Huijsduijnen R" first="Rob" last="Hooft Van Huijsduijnen">Rob Hooft Van Huijsduijnen</name>
<affiliation wicri:level="1"><nlm:affiliation>Medicines for Malaria Venture, Geneva, Switzerland.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Medicines for Malaria Venture, Geneva</wicri:regionArea>
<wicri:noRegion>Geneva</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Horii, Takaaki" sort="Horii, Takaaki" uniqKey="Horii T" first="Takaaki" last="Horii">Takaaki Horii</name>
<affiliation wicri:level="1"><nlm:affiliation>Global Health Research Section, hhc Data Creation Center, Eisai Co., Ltd, Tsukuba-shi, Ibaraki, Japan.</nlm:affiliation>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Global Health Research Section, hhc Data Creation Center, Eisai Co., Ltd, Tsukuba-shi, Ibaraki</wicri:regionArea>
<wicri:noRegion>Ibaraki</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Horrocks, Paul" sort="Horrocks, Paul" uniqKey="Horrocks P" first="Paul" last="Horrocks">Paul Horrocks</name>
<affiliation wicri:level="1"><nlm:affiliation>Institute for Science and Technology in Medicine, Keele University, Keele, Staffordshire, United Kingdom.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Institute for Science and Technology in Medicine, Keele University, Keele, Staffordshire</wicri:regionArea>
<wicri:noRegion>Staffordshire</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Hughes, Tyler B" sort="Hughes, Tyler B" uniqKey="Hughes T" first="Tyler B" last="Hughes">Tyler B. Hughes</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Pathology and Immunology, Washington University in St Louis, St. Louis, Missouri, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Pathology and Immunology, Washington University in St Louis, St. Louis, Missouri</wicri:regionArea>
<placeName><region type="state">Missouri (État)</region>
<settlement type="city">Saint-Louis (Missouri)</settlement>
</placeName>
<orgName type="university">Université Washington de Saint-Louis</orgName>
</affiliation>
</author>
<author><name sortKey="Huston, Christopher" sort="Huston, Christopher" uniqKey="Huston C" first="Christopher" last="Huston">Christopher Huston</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Medicine, College of Medicine, University of Vermont, Burlington, Vermont, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Medicine, College of Medicine, University of Vermont, Burlington, Vermont</wicri:regionArea>
<placeName><region type="state">Vermont</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Igarashi, Ikuo" sort="Igarashi, Ikuo" uniqKey="Igarashi I" first="Ikuo" last="Igarashi">Ikuo Igarashi</name>
<affiliation wicri:level="1"><nlm:affiliation>National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, Japan.</nlm:affiliation>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido</wicri:regionArea>
<wicri:noRegion>Hokkaido</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Ingram Sieber, Katrin" sort="Ingram Sieber, Katrin" uniqKey="Ingram Sieber K" first="Katrin" last="Ingram-Sieber">Katrin Ingram-Sieber</name>
<affiliation wicri:level="1"><nlm:affiliation>Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Basel, Switzerland.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Basel</wicri:regionArea>
<wicri:noRegion>Basel</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Itoe, Maurice A" sort="Itoe, Maurice A" uniqKey="Itoe M" first="Maurice A" last="Itoe">Maurice A. Itoe</name>
<affiliation wicri:level="1"><nlm:affiliation>Instituto de Medicina Molecular, Lisboa, Portugal.</nlm:affiliation>
<country xml:lang="fr">Portugal</country>
<wicri:regionArea>Instituto de Medicina Molecular, Lisboa</wicri:regionArea>
<wicri:noRegion>Lisboa</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Jadhav, Ajit" sort="Jadhav, Ajit" uniqKey="Jadhav A" first="Ajit" last="Jadhav">Ajit Jadhav</name>
<affiliation wicri:level="2"><nlm:affiliation>National Center of Advancing Translational Sciences, NIH, Bethesda, Maryland, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>National Center of Advancing Translational Sciences, NIH, Bethesda, Maryland</wicri:regionArea>
<placeName><region type="state">Maryland</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Naranuntarat Jensen, Amornrat" sort="Naranuntarat Jensen, Amornrat" uniqKey="Naranuntarat Jensen A" first="Amornrat" last="Naranuntarat Jensen">Amornrat Naranuntarat Jensen</name>
<affiliation><nlm:affiliation>Department of Pathobiology, Faculty of Science, Mahidol University, Bangkok Thailand.</nlm:affiliation>
<wicri:noCountry code="subField">Bangkok Thailand</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Jensen, Laran T" sort="Jensen, Laran T" uniqKey="Jensen L" first="Laran T" last="Jensen">Laran T. Jensen</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Biochemistry, Mahidol University, Bangkok, Thailand.</nlm:affiliation>
<country xml:lang="fr">Thaïlande</country>
<wicri:regionArea>Department of Biochemistry, Mahidol University, Bangkok</wicri:regionArea>
<wicri:noRegion>Bangkok</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Jiang, Rays H Y" sort="Jiang, Rays H Y" uniqKey="Jiang R" first="Rays H Y" last="Jiang">Rays H Y. Jiang</name>
<affiliation wicri:level="4"><nlm:affiliation>Center for Global Health and Infectious Diseases Research, Department of Global Health, University of South Florida, Tampa, Florida, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Center for Global Health and Infectious Diseases Research, Department of Global Health, University of South Florida, Tampa, Florida</wicri:regionArea>
<placeName><region type="state">Floride</region>
<settlement type="city">Tampa</settlement>
</placeName>
<orgName type="university">Université de Floride du Sud</orgName>
</affiliation>
</author>
<author><name sortKey="Kaiser, Annette" sort="Kaiser, Annette" uniqKey="Kaiser A" first="Annette" last="Kaiser">Annette Kaiser</name>
<affiliation wicri:level="1"><nlm:affiliation>Medical Research Centre, Institute for Pharmacogenetics, Essen, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Medical Research Centre, Institute for Pharmacogenetics, Essen</wicri:regionArea>
<wicri:noRegion>Essen</wicri:noRegion>
<wicri:noRegion>Essen</wicri:noRegion>
<wicri:noRegion>Essen</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Keiser, Jennifer" sort="Keiser, Jennifer" uniqKey="Keiser J" first="Jennifer" last="Keiser">Jennifer Keiser</name>
<affiliation wicri:level="1"><nlm:affiliation>Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Basel, Switzerland.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Basel</wicri:regionArea>
<wicri:noRegion>Basel</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Ketas, Thomas" sort="Ketas, Thomas" uniqKey="Ketas T" first="Thomas" last="Ketas">Thomas Ketas</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Microbiology and Immunology, Weill Cornell Medical College, New York, New York, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Microbiology and Immunology, Weill Cornell Medical College, New York, New York</wicri:regionArea>
<placeName><region type="state">État de New York</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Kicka, Sebastien" sort="Kicka, Sebastien" uniqKey="Kicka S" first="Sebastien" last="Kicka">Sebastien Kicka</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Biochemistry, University of Geneva, Geneva, Switzerland.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Department of Biochemistry, University of Geneva, Geneva</wicri:regionArea>
<orgName type="university">Université de Genève</orgName>
<placeName><settlement type="city">Genève</settlement>
<region nuts="3" type="region">Canton de Genève</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Kim, Sunyoung" sort="Kim, Sunyoung" uniqKey="Kim S" first="Sunyoung" last="Kim">Sunyoung Kim</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Biochemistry and Molecular Biology, LSU Health Sciences Center, New Orleans, Louisiana, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Biochemistry and Molecular Biology, LSU Health Sciences Center, New Orleans, Louisiana</wicri:regionArea>
<placeName><region type="state">Louisiane</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Kirk, Kiaran" sort="Kirk, Kiaran" uniqKey="Kirk K" first="Kiaran" last="Kirk">Kiaran Kirk</name>
<affiliation wicri:level="1"><nlm:affiliation>Research School of Biology, Australian National University, Canberra, Australian Capital Territory, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Research School of Biology, Australian National University, Canberra, Australian Capital Territory</wicri:regionArea>
<wicri:noRegion>Australian Capital Territory</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Kumar, Vidya P" sort="Kumar, Vidya P" uniqKey="Kumar V" first="Vidya P" last="Kumar">Vidya P. Kumar</name>
<affiliation wicri:level="2"><nlm:affiliation>Internal Medicine, Yale University, New Haven, Connecticut, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Internal Medicine, Yale University, New Haven, Connecticut</wicri:regionArea>
<placeName><region type="state">Connecticut</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Kyle, Dennis E" sort="Kyle, Dennis E" uniqKey="Kyle D" first="Dennis E" last="Kyle">Dennis E. Kyle</name>
<affiliation wicri:level="4"><nlm:affiliation>Center for Global Health and Infectious Diseases Research, Department of Global Health, University of South Florida, Tampa, Florida, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Center for Global Health and Infectious Diseases Research, Department of Global Health, University of South Florida, Tampa, Florida</wicri:regionArea>
<placeName><region type="state">Floride</region>
<settlement type="city">Tampa</settlement>
</placeName>
<orgName type="university">Université de Floride du Sud</orgName>
</affiliation>
</author>
<author><name sortKey="Lafuente, Maria Jose" sort="Lafuente, Maria Jose" uniqKey="Lafuente M" first="Maria Jose" last="Lafuente">Maria Jose Lafuente</name>
<affiliation wicri:level="3"><nlm:affiliation>Biochemistry and Parasitology Department, Malaria DPU, Diseases of the Developing World (DDW), GlaxoSmithKline R&D, Tres Cantos, Madrid, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Biochemistry and Parasitology Department, Malaria DPU, Diseases of the Developing World (DDW), GlaxoSmithKline R&D, Tres Cantos, Madrid</wicri:regionArea>
<placeName><settlement type="city">Madrid</settlement>
<region nuts="2" type="region">Communauté de Madrid</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Landfear, Scott" sort="Landfear, Scott" uniqKey="Landfear S" first="Scott" last="Landfear">Scott Landfear</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Molecular Microbiology & Immunology, Oregon Health & Science University, Portland, Oregon, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Molecular Microbiology & Immunology, Oregon Health & Science University, Portland, Oregon</wicri:regionArea>
<placeName><region type="state">Oregon</region>
<settlement type="city">Portland</settlement>
</placeName>
<orgName type="university">Université des sciences et de la médecine de l'Oregon</orgName>
</affiliation>
</author>
<author><name sortKey="Lee, Nathan" sort="Lee, Nathan" uniqKey="Lee N" first="Nathan" last="Lee">Nathan Lee</name>
<affiliation wicri:level="1"><nlm:affiliation>Medicines for Malaria Venture, Geneva, Switzerland.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Medicines for Malaria Venture, Geneva</wicri:regionArea>
<wicri:noRegion>Geneva</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Lee, Sukjun" sort="Lee, Sukjun" uniqKey="Lee S" first="Sukjun" last="Lee">Sukjun Lee</name>
<affiliation wicri:level="1"><nlm:affiliation>Institut Pasteur Korea, Pangyo Techno-Valley, Gyeonggi Province, Korea.</nlm:affiliation>
<country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea>Institut Pasteur Korea, Pangyo Techno-Valley, Gyeonggi Province</wicri:regionArea>
<wicri:noRegion>Gyeonggi Province</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Lehane, Adele M" sort="Lehane, Adele M" uniqKey="Lehane A" first="Adele M" last="Lehane">Adele M. Lehane</name>
<affiliation wicri:level="1"><nlm:affiliation>Research School of Biology, Australian National University, Canberra, Australian Capital Territory, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Research School of Biology, Australian National University, Canberra, Australian Capital Territory</wicri:regionArea>
<wicri:noRegion>Australian Capital Territory</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Li, Fengwu" sort="Li, Fengwu" uniqKey="Li F" first="Fengwu" last="Li">Fengwu Li</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Molecular Microbiology & Immunology, Oregon Health & Science University, Portland, Oregon, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Molecular Microbiology & Immunology, Oregon Health & Science University, Portland, Oregon</wicri:regionArea>
<placeName><region type="state">Oregon</region>
<settlement type="city">Portland</settlement>
</placeName>
<orgName type="university">Université des sciences et de la médecine de l'Oregon</orgName>
</affiliation>
</author>
<author><name sortKey="Little, David" sort="Little, David" uniqKey="Little D" first="David" last="Little">David Little</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Microbiology and Immunology, Weill Cornell Medical College, New York, New York, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Microbiology and Immunology, Weill Cornell Medical College, New York, New York</wicri:regionArea>
<placeName><region type="state">État de New York</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Liu, Liqiong" sort="Liu, Liqiong" uniqKey="Liu L" first="Liqiong" last="Liu">Liqiong Liu</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Biochemistry and Molecular Biology, LSU Health Sciences Center, New Orleans, Louisiana, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Biochemistry and Molecular Biology, LSU Health Sciences Center, New Orleans, Louisiana</wicri:regionArea>
<placeName><region type="state">Louisiane</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Llinas, Manuel" sort="Llinas, Manuel" uniqKey="Llinas M" first="Manuel" last="Llinás">Manuel Llinás</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Biochemistry and Molecular Biology and Huck Center for Malaria Research, Pennsylvania State University, University Park, Pennsylvania, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Biochemistry and Molecular Biology and Huck Center for Malaria Research, Pennsylvania State University, University Park, Pennsylvania</wicri:regionArea>
<placeName><region type="state">Pennsylvanie</region>
<settlement type="city">University Park (Pennsylvanie)</settlement>
</placeName>
<orgName type="university">Université d'État de Pennsylvanie</orgName>
</affiliation>
</author>
<author><name sortKey="Loza, Maria I" sort="Loza, Maria I" uniqKey="Loza M" first="Maria I" last="Loza">Maria I. Loza</name>
<affiliation wicri:level="4"><nlm:affiliation>CIMUS Research Centre, University of Santiago de Compostela, Santiago de Compostela, A Coruña, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>CIMUS Research Centre, University of Santiago de Compostela, Santiago de Compostela, A Coruña</wicri:regionArea>
<orgName type="university">Université de Saint-Jacques-de-Compostelle</orgName>
<placeName><settlement type="city">Santiago de Compostela</settlement>
<region nuts="2" type="region">Galice</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Lubar, Aristea" sort="Lubar, Aristea" uniqKey="Lubar A" first="Aristea" last="Lubar">Aristea Lubar</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Medicine, University of California San Diego, San Diego, California, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Medicine, University of California San Diego, San Diego, California</wicri:regionArea>
<placeName><region type="state">Californie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Lucantoni, Leonardo" sort="Lucantoni, Leonardo" uniqKey="Lucantoni L" first="Leonardo" last="Lucantoni">Leonardo Lucantoni</name>
<affiliation wicri:level="1"><nlm:affiliation>Eskitis Institute for Drug Discovery, Griffith University, Nathan, QLD, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Eskitis Institute for Drug Discovery, Griffith University, Nathan, QLD</wicri:regionArea>
<wicri:noRegion>QLD</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Lucet, Isabelle" sort="Lucet, Isabelle" uniqKey="Lucet I" first="Isabelle" last="Lucet">Isabelle Lucet</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Biochemistry and Molecular Biology, Monash University, Clayton, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Department of Biochemistry and Molecular Biology, Monash University, Clayton</wicri:regionArea>
<wicri:noRegion>Clayton</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Maes, Louis" sort="Maes, Louis" uniqKey="Maes L" first="Louis" last="Maes">Louis Maes</name>
<affiliation wicri:level="4"><nlm:affiliation>University of Antwerp, Department of Biomedical Sciences, Antwerp, Belgium.</nlm:affiliation>
<country xml:lang="fr">Belgique</country>
<wicri:regionArea>University of Antwerp, Department of Biomedical Sciences, Antwerp</wicri:regionArea>
<orgName type="university">Université d'Anvers</orgName>
<placeName><settlement type="city">Anvers</settlement>
<region type="district" nuts="2">Province d'Anvers</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Mancama, Dalu" sort="Mancama, Dalu" uniqKey="Mancama D" first="Dalu" last="Mancama">Dalu Mancama</name>
<affiliation wicri:level="1"><nlm:affiliation>Biosciences Unit, Council for Scientific and Industrial Research, Pretoria, South Africa.</nlm:affiliation>
<country xml:lang="fr">Afrique du Sud</country>
<wicri:regionArea>Biosciences Unit, Council for Scientific and Industrial Research, Pretoria</wicri:regionArea>
<wicri:noRegion>Pretoria</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Mansour, Nuha R" sort="Mansour, Nuha R" uniqKey="Mansour N" first="Nuha R" last="Mansour">Nuha R. Mansour</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Immunology & Infection, London School of Hygiene and Tropical Medicine, London, England, United Kingdom.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Immunology & Infection, London School of Hygiene and Tropical Medicine, London, England</wicri:regionArea>
<wicri:noRegion>England</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="March, Sandra" sort="March, Sandra" uniqKey="March S" first="Sandra" last="March">Sandra March</name>
<affiliation wicri:level="2"><nlm:affiliation>Health Sciences and Technology/Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Health Sciences and Technology/Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, Massachusetts</wicri:regionArea>
<placeName><region type="state">Massachusetts</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Mcgowan, Sheena" sort="Mcgowan, Sheena" uniqKey="Mcgowan S" first="Sheena" last="Mcgowan">Sheena Mcgowan</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Microbiology, Monash University, Clayton, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Department of Microbiology, Monash University, Clayton</wicri:regionArea>
<wicri:noRegion>Clayton</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Medina Vera, Iset" sort="Medina Vera, Iset" uniqKey="Medina Vera I" first="Iset" last="Medina Vera">Iset Medina Vera</name>
<affiliation wicri:level="1"><nlm:affiliation>Instituto de Medicina Molecular, Lisboa, Portugal.</nlm:affiliation>
<country xml:lang="fr">Portugal</country>
<wicri:regionArea>Instituto de Medicina Molecular, Lisboa</wicri:regionArea>
<wicri:noRegion>Lisboa</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Meister, Stephan" sort="Meister, Stephan" uniqKey="Meister S" first="Stephan" last="Meister">Stephan Meister</name>
<affiliation wicri:level="2"><nlm:affiliation>Division of Pharmacology and Drug Discovery, Department of Pediatrics, School of Medicine University of California San Diego, La Jolla, California, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Division of Pharmacology and Drug Discovery, Department of Pediatrics, School of Medicine University of California San Diego, La Jolla, California</wicri:regionArea>
<placeName><region type="state">Californie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Mercer, Luke" sort="Mercer, Luke" uniqKey="Mercer L" first="Luke" last="Mercer">Luke Mercer</name>
<affiliation wicri:level="2"><nlm:affiliation>SCYNEXIS, Inc., Durham, North Carolina, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>SCYNEXIS, Inc., Durham, North Carolina</wicri:regionArea>
<placeName><region type="state">Caroline du Nord</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Mestres, Jordi" sort="Mestres, Jordi" uniqKey="Mestres J" first="Jordi" last="Mestres">Jordi Mestres</name>
<affiliation wicri:level="1"><nlm:affiliation>Chemotargets S.L. and Research Group on Systems Pharmacology, Research Program on Biomedical Informatics (GRIB), IMIM Hospital del Mar Institute of Medical Research and University Pompeu Fabra, Barcelona, Catalonia, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Chemotargets S.L. and Research Group on Systems Pharmacology, Research Program on Biomedical Informatics (GRIB), IMIM Hospital del Mar Institute of Medical Research and University Pompeu Fabra, Barcelona, Catalonia</wicri:regionArea>
<wicri:noRegion>Catalonia</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Mfopa, Alvine N" sort="Mfopa, Alvine N" uniqKey="Mfopa A" first="Alvine N" last="Mfopa">Alvine N. Mfopa</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Biochemistry, University of Yaoundé, Yaoundé, Cameroon.</nlm:affiliation>
<country xml:lang="fr">Cameroun</country>
<wicri:regionArea>Department of Biochemistry, University of Yaoundé, Yaoundé</wicri:regionArea>
<wicri:noRegion>Yaoundé</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Misra, Raj N" sort="Misra, Raj N" uniqKey="Misra R" first="Raj N" last="Misra">Raj N. Misra</name>
<affiliation wicri:level="2"><nlm:affiliation>Division of Cancer Therapeutics and Diagnosis, Drug Synthesis and Chemistry Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Division of Cancer Therapeutics and Diagnosis, Drug Synthesis and Chemistry Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland</wicri:regionArea>
<placeName><region type="state">Maryland</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Moon, Seunghyun" sort="Moon, Seunghyun" uniqKey="Moon S" first="Seunghyun" last="Moon">Seunghyun Moon</name>
<affiliation wicri:level="1"><nlm:affiliation>Institut Pasteur Korea, Pangyo Techno-Valley, Gyeonggi Province, Korea.</nlm:affiliation>
<country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea>Institut Pasteur Korea, Pangyo Techno-Valley, Gyeonggi Province</wicri:regionArea>
<wicri:noRegion>Gyeonggi Province</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Moore, John P" sort="Moore, John P" uniqKey="Moore J" first="John P" last="Moore">John P. Moore</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Microbiology and Immunology, Weill Cornell Medical College, New York, New York, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Microbiology and Immunology, Weill Cornell Medical College, New York, New York</wicri:regionArea>
<placeName><region type="state">État de New York</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Morais Rodrigues Da Costa, Francielly" sort="Morais Rodrigues Da Costa, Francielly" uniqKey="Morais Rodrigues Da Costa F" first="Francielly" last="Morais Rodrigues Da Costa">Francielly Morais Rodrigues Da Costa</name>
<affiliation wicri:level="4"><nlm:affiliation>Graduate Program in Bioinformatics, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.</nlm:affiliation>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Graduate Program in Bioinformatics, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais</wicri:regionArea>
<placeName><region type="state">Minas Gerais</region>
<settlement type="city">Belo Horizonte</settlement>
</placeName>
<orgName type="university">Université fédérale du Minas Gerais</orgName>
</affiliation>
</author>
<author><name sortKey="Muller, Joachim" sort="Muller, Joachim" uniqKey="Muller J" first="Joachim" last="Müller">Joachim Müller</name>
<affiliation wicri:level="3"><nlm:affiliation>Institute of Parasitology, University of Berne, Bern, Switzerland.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Institute of Parasitology, University of Berne, Bern</wicri:regionArea>
<placeName><settlement type="city">Berne</settlement>
<region type="région" nuts="3">Canton de Berne</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Muriana, Arantza" sort="Muriana, Arantza" uniqKey="Muriana A" first="Arantza" last="Muriana">Arantza Muriana</name>
<affiliation wicri:level="1"><nlm:affiliation>BBD BioPhenix SL-BIOBIDE, Donostia, Gipuzkoa, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>BBD BioPhenix SL-BIOBIDE, Donostia, Gipuzkoa</wicri:regionArea>
<wicri:noRegion>Gipuzkoa</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Nakazawa Hewitt, Stephen" sort="Nakazawa Hewitt, Stephen" uniqKey="Nakazawa Hewitt S" first="Stephen" last="Nakazawa Hewitt">Stephen Nakazawa Hewitt</name>
<affiliation wicri:level="4"><nlm:affiliation>Departments of Medicine, Microbiology, and Global Health, Center for Emerging and Re-emerging Infectious Diseases (CERID) University of Washington, Seattle, Washington, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Departments of Medicine, Microbiology, and Global Health, Center for Emerging and Re-emerging Infectious Diseases (CERID) University of Washington, Seattle, Washington</wicri:regionArea>
<placeName><region type="state">Washington (État)</region>
<settlement type="city">Seattle</settlement>
</placeName>
<orgName type="university">Université de Washington</orgName>
</affiliation>
</author>
<author><name sortKey="Nare, Bakela" sort="Nare, Bakela" uniqKey="Nare B" first="Bakela" last="Nare">Bakela Nare</name>
<affiliation wicri:level="2"><nlm:affiliation>SCYNEXIS, Inc., Durham, North Carolina, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>SCYNEXIS, Inc., Durham, North Carolina</wicri:regionArea>
<placeName><region type="state">Caroline du Nord</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Nathan, Carl" sort="Nathan, Carl" uniqKey="Nathan C" first="Carl" last="Nathan">Carl Nathan</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Microbiology and Immunology, Weill Cornell Medical College, New York, New York, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Microbiology and Immunology, Weill Cornell Medical College, New York, New York</wicri:regionArea>
<placeName><region type="state">État de New York</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Narraidoo, Nathalie" sort="Narraidoo, Nathalie" uniqKey="Narraidoo N" first="Nathalie" last="Narraidoo">Nathalie Narraidoo</name>
<affiliation wicri:level="4"><nlm:affiliation>School of Life Sciences, University of Nottingham, Nottingham, Nottinghamshire, England, United Kingdom.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>School of Life Sciences, University of Nottingham, Nottingham, Nottinghamshire, England</wicri:regionArea>
<orgName type="university">Université de Nottingham</orgName>
<placeName><settlement type="city">Nottingham</settlement>
<region type="nation">Angleterre</region>
<region type="région" nuts="1">Nottinghamshire</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Nawaratna, Sujeevi" sort="Nawaratna, Sujeevi" uniqKey="Nawaratna S" first="Sujeevi" last="Nawaratna">Sujeevi Nawaratna</name>
<affiliation wicri:level="1"><nlm:affiliation>Eskitis Institute for Drug Discovery, Griffith University, Nathan, QLD, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Eskitis Institute for Drug Discovery, Griffith University, Nathan, QLD</wicri:regionArea>
<wicri:noRegion>QLD</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Ojo, Kayode K" sort="Ojo, Kayode K" uniqKey="Ojo K" first="Kayode K" last="Ojo">Kayode K. Ojo</name>
<affiliation wicri:level="4"><nlm:affiliation>Departments of Medicine, Microbiology, and Global Health, Center for Emerging and Re-emerging Infectious Diseases (CERID) University of Washington, Seattle, Washington, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Departments of Medicine, Microbiology, and Global Health, Center for Emerging and Re-emerging Infectious Diseases (CERID) University of Washington, Seattle, Washington</wicri:regionArea>
<placeName><region type="state">Washington (État)</region>
<settlement type="city">Seattle</settlement>
</placeName>
<orgName type="university">Université de Washington</orgName>
</affiliation>
</author>
<author><name sortKey="Ortiz, Diana" sort="Ortiz, Diana" uniqKey="Ortiz D" first="Diana" last="Ortiz">Diana Ortiz</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Molecular Microbiology & Immunology, Oregon Health & Science University, Portland, Oregon, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Molecular Microbiology & Immunology, Oregon Health & Science University, Portland, Oregon</wicri:regionArea>
<placeName><region type="state">Oregon</region>
<settlement type="city">Portland</settlement>
</placeName>
<orgName type="university">Université des sciences et de la médecine de l'Oregon</orgName>
</affiliation>
</author>
<author><name sortKey="Panic, Gordana" sort="Panic, Gordana" uniqKey="Panic G" first="Gordana" last="Panic">Gordana Panic</name>
<affiliation wicri:level="1"><nlm:affiliation>Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Basel, Switzerland.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Basel</wicri:regionArea>
<wicri:noRegion>Basel</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Papadatos, George" sort="Papadatos, George" uniqKey="Papadatos G" first="George" last="Papadatos">George Papadatos</name>
<affiliation wicri:level="1"><nlm:affiliation>ChEMBL group, European Molecular Biology Laboratory-European Bioinformatics Institute (EMBL-EBI), Hinxton, Cambridgeshire, United Kingdom.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>ChEMBL group, European Molecular Biology Laboratory-European Bioinformatics Institute (EMBL-EBI), Hinxton, Cambridgeshire</wicri:regionArea>
<wicri:noRegion>Cambridgeshire</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Parapini, Silvia" sort="Parapini, Silvia" uniqKey="Parapini S" first="Silvia" last="Parapini">Silvia Parapini</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Pharmacological and Biomolecular Sciences, Università degli Studi di Milano, Milano, Italy.</nlm:affiliation>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Department of Pharmacological and Biomolecular Sciences, Università degli Studi di Milano, Milano</wicri:regionArea>
<wicri:noRegion>Milano</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Patra, Kailash" sort="Patra, Kailash" uniqKey="Patra K" first="Kailash" last="Patra">Kailash Patra</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Medicine, University of California San Diego, San Diego, California, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Medicine, University of California San Diego, San Diego, California</wicri:regionArea>
<placeName><region type="state">Californie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Pham, Ngoc" sort="Pham, Ngoc" uniqKey="Pham N" first="Ngoc" last="Pham">Ngoc Pham</name>
<affiliation wicri:level="1"><nlm:affiliation>Eskitis Institute for Drug Discovery, Griffith University, Nathan, QLD, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Eskitis Institute for Drug Discovery, Griffith University, Nathan, QLD</wicri:regionArea>
<wicri:noRegion>QLD</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Prats, Sarah" sort="Prats, Sarah" uniqKey="Prats S" first="Sarah" last="Prats">Sarah Prats</name>
<affiliation wicri:level="3"><nlm:affiliation>Biochemistry and Parasitology Department, Malaria DPU, Diseases of the Developing World (DDW), GlaxoSmithKline R&D, Tres Cantos, Madrid, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Biochemistry and Parasitology Department, Malaria DPU, Diseases of the Developing World (DDW), GlaxoSmithKline R&D, Tres Cantos, Madrid</wicri:regionArea>
<placeName><settlement type="city">Madrid</settlement>
<region nuts="2" type="region">Communauté de Madrid</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Plouffe, David M" sort="Plouffe, David M" uniqKey="Plouffe D" first="David M" last="Plouffe">David M. Plouffe</name>
<affiliation wicri:level="2"><nlm:affiliation>Genomics Institute of the Novartis Research Foundation, San Diego, California, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Genomics Institute of the Novartis Research Foundation, San Diego, California</wicri:regionArea>
<placeName><region type="state">Californie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Poulsen, Sally Ann" sort="Poulsen, Sally Ann" uniqKey="Poulsen S" first="Sally-Ann" last="Poulsen">Sally-Ann Poulsen</name>
<affiliation wicri:level="1"><nlm:affiliation>Eskitis Institute for Drug Discovery, Griffith University, Nathan, QLD, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Eskitis Institute for Drug Discovery, Griffith University, Nathan, QLD</wicri:regionArea>
<wicri:noRegion>QLD</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Pradhan, Anupam" sort="Pradhan, Anupam" uniqKey="Pradhan A" first="Anupam" last="Pradhan">Anupam Pradhan</name>
<affiliation wicri:level="4"><nlm:affiliation>Center for Global Health and Infectious Diseases Research, Department of Global Health, University of South Florida, Tampa, Florida, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Center for Global Health and Infectious Diseases Research, Department of Global Health, University of South Florida, Tampa, Florida</wicri:regionArea>
<placeName><region type="state">Floride</region>
<settlement type="city">Tampa</settlement>
</placeName>
<orgName type="university">Université de Floride du Sud</orgName>
</affiliation>
</author>
<author><name sortKey="Quevedo, Celia" sort="Quevedo, Celia" uniqKey="Quevedo C" first="Celia" last="Quevedo">Celia Quevedo</name>
<affiliation wicri:level="1"><nlm:affiliation>BBD BioPhenix SL-BIOBIDE, Donostia, Gipuzkoa, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>BBD BioPhenix SL-BIOBIDE, Donostia, Gipuzkoa</wicri:regionArea>
<wicri:noRegion>Gipuzkoa</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Quinn, Ronald J" sort="Quinn, Ronald J" uniqKey="Quinn R" first="Ronald J" last="Quinn">Ronald J. Quinn</name>
<affiliation wicri:level="1"><nlm:affiliation>Eskitis Institute for Drug Discovery, Griffith University, Nathan, QLD, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Eskitis Institute for Drug Discovery, Griffith University, Nathan, QLD</wicri:regionArea>
<wicri:noRegion>QLD</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Rice, Christopher A" sort="Rice, Christopher A" uniqKey="Rice C" first="Christopher A" last="Rice">Christopher A. Rice</name>
<affiliation wicri:level="4"><nlm:affiliation>Center for Global Health and Infectious Diseases Research, Department of Global Health, University of South Florida, Tampa, Florida, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Center for Global Health and Infectious Diseases Research, Department of Global Health, University of South Florida, Tampa, Florida</wicri:regionArea>
<placeName><region type="state">Floride</region>
<settlement type="city">Tampa</settlement>
</placeName>
<orgName type="university">Université de Floride du Sud</orgName>
</affiliation>
</author>
<author><name sortKey="Abdo Rizk, Mohamed" sort="Abdo Rizk, Mohamed" uniqKey="Abdo Rizk M" first="Mohamed" last="Abdo Rizk">Mohamed Abdo Rizk</name>
<affiliation wicri:level="1"><nlm:affiliation>National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, Japan.</nlm:affiliation>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido</wicri:regionArea>
<wicri:noRegion>Hokkaido</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Ruecker, Andrea" sort="Ruecker, Andrea" uniqKey="Ruecker A" first="Andrea" last="Ruecker">Andrea Ruecker</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Life Sciences, Imperial College London, London, England, United Kingdom.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Life Sciences, Imperial College London, London, England</wicri:regionArea>
<wicri:noRegion>England</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="St Onge, Robert" sort="St Onge, Robert" uniqKey="St Onge R" first="Robert" last="St Onge">Robert St Onge</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Biochemistry and Stanford Genome Technology Center, Stanford University, Palo Alto, Calilfornia, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Biochemistry and Stanford Genome Technology Center, Stanford University, Palo Alto, Calilfornia</wicri:regionArea>
<wicri:noRegion>Calilfornia</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Salgado Ferreira, Rafaela" sort="Salgado Ferreira, Rafaela" uniqKey="Salgado Ferreira R" first="Rafaela" last="Salgado Ferreira">Rafaela Salgado Ferreira</name>
<affiliation wicri:level="4"><nlm:affiliation>Departamento de Bioquímica e Imunologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.</nlm:affiliation>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Departamento de Bioquímica e Imunologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais</wicri:regionArea>
<placeName><region type="state">Minas Gerais</region>
<settlement type="city">Belo Horizonte</settlement>
</placeName>
<orgName type="university">Université fédérale du Minas Gerais</orgName>
</affiliation>
</author>
<author><name sortKey="Samra, Jasmeet" sort="Samra, Jasmeet" uniqKey="Samra J" first="Jasmeet" last="Samra">Jasmeet Samra</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Biochemistry and Molecular Biology and Huck Center for Malaria Research, Pennsylvania State University, University Park, Pennsylvania, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Biochemistry and Molecular Biology and Huck Center for Malaria Research, Pennsylvania State University, University Park, Pennsylvania</wicri:regionArea>
<placeName><region type="state">Pennsylvanie</region>
<settlement type="city">University Park (Pennsylvanie)</settlement>
</placeName>
<orgName type="university">Université d'État de Pennsylvanie</orgName>
</affiliation>
</author>
<author><name sortKey="Robinett, Natalie G" sort="Robinett, Natalie G" uniqKey="Robinett N" first="Natalie G" last="Robinett">Natalie G. Robinett</name>
<affiliation><nlm:affiliation>Department of Biochemistry and Molecular Biology and Johns Hopkins Malaria Research Institute, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, Untied States of America.</nlm:affiliation>
<wicri:noCountry code="subField">Untied States of America</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Schlecht, Ulrich" sort="Schlecht, Ulrich" uniqKey="Schlecht U" first="Ulrich" last="Schlecht">Ulrich Schlecht</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Biochemistry and Stanford Genome Technology Center, Stanford University, Palo Alto, Calilfornia, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Biochemistry and Stanford Genome Technology Center, Stanford University, Palo Alto, Calilfornia</wicri:regionArea>
<wicri:noRegion>Calilfornia</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Schmitt, Marjorie" sort="Schmitt, Marjorie" uniqKey="Schmitt M" first="Marjorie" last="Schmitt">Marjorie Schmitt</name>
<affiliation wicri:level="1"><nlm:affiliation>Laboratoire de Chimie Moléculaire, CNRS,-UMR 7509, COB-IRJBD, Mulhouse Cedex, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Laboratoire de Chimie Moléculaire, CNRS,-UMR 7509, COB-IRJBD, Mulhouse Cedex</wicri:regionArea>
<wicri:noRegion>Mulhouse Cedex</wicri:noRegion>
<wicri:noRegion>Mulhouse Cedex</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Silva Villela, Filipe" sort="Silva Villela, Filipe" uniqKey="Silva Villela F" first="Filipe" last="Silva Villela">Filipe Silva Villela</name>
<affiliation wicri:level="4"><nlm:affiliation>Departamento de Bioquímica e Imunologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.</nlm:affiliation>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Departamento de Bioquímica e Imunologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais</wicri:regionArea>
<placeName><region type="state">Minas Gerais</region>
<settlement type="city">Belo Horizonte</settlement>
</placeName>
<orgName type="university">Université fédérale du Minas Gerais</orgName>
</affiliation>
</author>
<author><name sortKey="Silvestrini, Francesco" sort="Silvestrini, Francesco" uniqKey="Silvestrini F" first="Francesco" last="Silvestrini">Francesco Silvestrini</name>
<affiliation wicri:level="3"><nlm:affiliation>Dipartimento Malattie Infettive, Parassitarie ed Immunomediate Istituto Superiore di Sanità, Roma, Italia.</nlm:affiliation>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Dipartimento Malattie Infettive, Parassitarie ed Immunomediate Istituto Superiore di Sanità, Roma</wicri:regionArea>
<placeName><settlement type="city">Rome</settlement>
<region nuts="2">Latium</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Sinden, Robert" sort="Sinden, Robert" uniqKey="Sinden R" first="Robert" last="Sinden">Robert Sinden</name>
<affiliation wicri:level="4"><nlm:affiliation>The Jenner Institute, University of Oxford, Oxford, England, United Kingdom.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>The Jenner Institute, University of Oxford, Oxford, England</wicri:regionArea>
<orgName type="university">Université d'Oxford</orgName>
<placeName><settlement type="city">Oxford</settlement>
<region type="nation">Angleterre</region>
<region type="région" nuts="1">Oxfordshire</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Smith, Dennis A" sort="Smith, Dennis A" uniqKey="Smith D" first="Dennis A" last="Smith">Dennis A. Smith</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Chemistry, University of Capetown, Capetown, South Africa.</nlm:affiliation>
<country xml:lang="fr">Afrique du Sud</country>
<wicri:regionArea>Department of Chemistry, University of Capetown, Capetown</wicri:regionArea>
<wicri:noRegion>Capetown</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Soldati, Thierry" sort="Soldati, Thierry" uniqKey="Soldati T" first="Thierry" last="Soldati">Thierry Soldati</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Biochemistry, University of Geneva, Geneva, Switzerland.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Department of Biochemistry, University of Geneva, Geneva</wicri:regionArea>
<orgName type="university">Université de Genève</orgName>
<placeName><settlement type="city">Genève</settlement>
<region nuts="3" type="region">Canton de Genève</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Spitzmuller, Andreas" sort="Spitzmuller, Andreas" uniqKey="Spitzmuller A" first="Andreas" last="Spitzmüller">Andreas Spitzmüller</name>
<affiliation wicri:level="1"><nlm:affiliation>Chemotargets S.L. and Research Group on Systems Pharmacology, Research Program on Biomedical Informatics (GRIB), IMIM Hospital del Mar Institute of Medical Research and University Pompeu Fabra, Barcelona, Catalonia, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Chemotargets S.L. and Research Group on Systems Pharmacology, Research Program on Biomedical Informatics (GRIB), IMIM Hospital del Mar Institute of Medical Research and University Pompeu Fabra, Barcelona, Catalonia</wicri:regionArea>
<wicri:noRegion>Catalonia</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Stamm, Serge Maximilian" sort="Stamm, Serge Maximilian" uniqKey="Stamm S" first="Serge Maximilian" last="Stamm">Serge Maximilian Stamm</name>
<affiliation><nlm:affiliation>Department of Biochemistry and Molecular Biology and Johns Hopkins Malaria Research Institute, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, Untied States of America.</nlm:affiliation>
<wicri:noCountry code="subField">Untied States of America</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Sullivan, David J" sort="Sullivan, David J" uniqKey="Sullivan D" first="David J" last="Sullivan">David J. Sullivan</name>
<affiliation wicri:level="2"><nlm:affiliation>H. Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins School of Public Health, Baltimore, Maryland, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>H. Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins School of Public Health, Baltimore, Maryland</wicri:regionArea>
<placeName><region type="state">Maryland</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Sullivan, William" sort="Sullivan, William" uniqKey="Sullivan W" first="William" last="Sullivan">William Sullivan</name>
<affiliation wicri:level="2"><nlm:affiliation>Molecular, Cell and Developmental Biology, University of California, Santa Cruz, Santa Cruz, California, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Molecular, Cell and Developmental Biology, University of California, Santa Cruz, Santa Cruz, California</wicri:regionArea>
<placeName><region type="state">Californie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Suresh, Sundari" sort="Suresh, Sundari" uniqKey="Suresh S" first="Sundari" last="Suresh">Sundari Suresh</name>
<affiliation wicri:level="4"><nlm:affiliation>Departamento de Bioquímica e Imunologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.</nlm:affiliation>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Departamento de Bioquímica e Imunologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais</wicri:regionArea>
<placeName><region type="state">Minas Gerais</region>
<settlement type="city">Belo Horizonte</settlement>
</placeName>
<orgName type="university">Université fédérale du Minas Gerais</orgName>
</affiliation>
</author>
<author><name sortKey="Suzuki, Brian M" sort="Suzuki, Brian M" uniqKey="Suzuki B" first="Brian M" last="Suzuki">Brian M. Suzuki</name>
<affiliation wicri:level="2"><nlm:affiliation>Center for Discovery and Innovation in Parasitic Diseases, Department of Pathology, University of California San Francisco, San Francisco, California, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Center for Discovery and Innovation in Parasitic Diseases, Department of Pathology, University of California San Francisco, San Francisco, California</wicri:regionArea>
<placeName><region type="state">Californie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Suzuki, Yo" sort="Suzuki, Yo" uniqKey="Suzuki Y" first="Yo" last="Suzuki">Yo Suzuki</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Synthetic Biology and Bioenergy, J. Craig Venter Institute, La Jolla, California, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Synthetic Biology and Bioenergy, J. Craig Venter Institute, La Jolla, California</wicri:regionArea>
<placeName><region type="state">Californie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Swamidass, S Joshua" sort="Swamidass, S Joshua" uniqKey="Swamidass S" first="S Joshua" last="Swamidass">S Joshua Swamidass</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Life Sciences, Imperial College London, London, England, United Kingdom.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Life Sciences, Imperial College London, London, England</wicri:regionArea>
<wicri:noRegion>England</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Taramelli, Donatella" sort="Taramelli, Donatella" uniqKey="Taramelli D" first="Donatella" last="Taramelli">Donatella Taramelli</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Pathology and Immunology, Washington University in St Louis, St. Louis, Missouri, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Pathology and Immunology, Washington University in St Louis, St. Louis, Missouri</wicri:regionArea>
<placeName><region type="state">Missouri (État)</region>
<settlement type="city">Saint-Louis (Missouri)</settlement>
</placeName>
<orgName type="university">Université Washington de Saint-Louis</orgName>
</affiliation>
</author>
<author><name sortKey="Tchokouaha, Lauve R Y" sort="Tchokouaha, Lauve R Y" uniqKey="Tchokouaha L" first="Lauve R Y" last="Tchokouaha">Lauve R Y. Tchokouaha</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Biochemistry, University of Yaoundé, Yaoundé, Cameroon.</nlm:affiliation>
<country xml:lang="fr">Cameroun</country>
<wicri:regionArea>Department of Biochemistry, University of Yaoundé, Yaoundé</wicri:regionArea>
<wicri:noRegion>Yaoundé</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Theron, Anjo" sort="Theron, Anjo" uniqKey="Theron A" first="Anjo" last="Theron">Anjo Theron</name>
<affiliation wicri:level="1"><nlm:affiliation>Biosciences Unit, Council for Scientific and Industrial Research, Pretoria, South Africa.</nlm:affiliation>
<country xml:lang="fr">Afrique du Sud</country>
<wicri:regionArea>Biosciences Unit, Council for Scientific and Industrial Research, Pretoria</wicri:regionArea>
<wicri:noRegion>Pretoria</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Thomas, David" sort="Thomas, David" uniqKey="Thomas D" first="David" last="Thomas">David Thomas</name>
<affiliation wicri:level="2"><nlm:affiliation>Broad Institute, Cambridge, Massachusetts, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Broad Institute, Cambridge, Massachusetts</wicri:regionArea>
<placeName><region type="state">Massachusetts</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Tonissen, Kathryn F" sort="Tonissen, Kathryn F" uniqKey="Tonissen K" first="Kathryn F" last="Tonissen">Kathryn F. Tonissen</name>
<affiliation wicri:level="1"><nlm:affiliation>Eskitis Institute for Drug Discovery, Griffith University, Nathan, QLD, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Eskitis Institute for Drug Discovery, Griffith University, Nathan, QLD</wicri:regionArea>
<wicri:noRegion>QLD</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Townson, Simon" sort="Townson, Simon" uniqKey="Townson S" first="Simon" last="Townson">Simon Townson</name>
<affiliation wicri:level="1"><nlm:affiliation>Tropical Parasitic Diseases Unit, Northwick Park Institute for Medical Research, Harrow, Middlesex, England, United Kingdom.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Tropical Parasitic Diseases Unit, Northwick Park Institute for Medical Research, Harrow, Middlesex, England</wicri:regionArea>
<wicri:noRegion>England</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Tripathi, Abhai K" sort="Tripathi, Abhai K" uniqKey="Tripathi A" first="Abhai K" last="Tripathi">Abhai K. Tripathi</name>
<affiliation wicri:level="2"><nlm:affiliation>H. Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins School of Public Health, Baltimore, Maryland, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>H. Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins School of Public Health, Baltimore, Maryland</wicri:regionArea>
<placeName><region type="state">Maryland</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Trofimov, Valentin" sort="Trofimov, Valentin" uniqKey="Trofimov V" first="Valentin" last="Trofimov">Valentin Trofimov</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Biochemistry, University of Geneva, Geneva, Switzerland.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Department of Biochemistry, University of Geneva, Geneva</wicri:regionArea>
<orgName type="university">Université de Genève</orgName>
<placeName><settlement type="city">Genève</settlement>
<region nuts="3" type="region">Canton de Genève</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Udenze, Kenneth O" sort="Udenze, Kenneth O" uniqKey="Udenze K" first="Kenneth O" last="Udenze">Kenneth O. Udenze</name>
<affiliation wicri:level="4"><nlm:affiliation>Center for Global Health and Infectious Diseases Research, Department of Global Health, University of South Florida, Tampa, Florida, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Center for Global Health and Infectious Diseases Research, Department of Global Health, University of South Florida, Tampa, Florida</wicri:regionArea>
<placeName><region type="state">Floride</region>
<settlement type="city">Tampa</settlement>
</placeName>
<orgName type="university">Université de Floride du Sud</orgName>
</affiliation>
</author>
<author><name sortKey="Ullah, Imran" sort="Ullah, Imran" uniqKey="Ullah I" first="Imran" last="Ullah">Imran Ullah</name>
<affiliation wicri:level="1"><nlm:affiliation>Institute for Science and Technology in Medicine, Keele University, Keele, Staffordshire, United Kingdom.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Institute for Science and Technology in Medicine, Keele University, Keele, Staffordshire</wicri:regionArea>
<wicri:noRegion>Staffordshire</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Vallieres, Cindy" sort="Vallieres, Cindy" uniqKey="Vallieres C" first="Cindy" last="Vallieres">Cindy Vallieres</name>
<affiliation wicri:level="4"><nlm:affiliation>School of Life Sciences, University of Nottingham, Nottingham, Nottinghamshire, England, United Kingdom.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>School of Life Sciences, University of Nottingham, Nottingham, Nottinghamshire, England</wicri:regionArea>
<orgName type="university">Université de Nottingham</orgName>
<placeName><settlement type="city">Nottingham</settlement>
<region type="nation">Angleterre</region>
<region type="région" nuts="1">Nottinghamshire</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Vigil, Edgar" sort="Vigil, Edgar" uniqKey="Vigil E" first="Edgar" last="Vigil">Edgar Vigil</name>
<affiliation wicri:level="2"><nlm:affiliation>Division of Pharmacology and Drug Discovery, Department of Pediatrics, School of Medicine University of California San Diego, La Jolla, California, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Division of Pharmacology and Drug Discovery, Department of Pediatrics, School of Medicine University of California San Diego, La Jolla, California</wicri:regionArea>
<placeName><region type="state">Californie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Vinetz, Joseph M" sort="Vinetz, Joseph M" uniqKey="Vinetz J" first="Joseph M" last="Vinetz">Joseph M. Vinetz</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Medicine, University of California San Diego, San Diego, California, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Medicine, University of California San Diego, San Diego, California</wicri:regionArea>
<placeName><region type="state">Californie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Voong Vinh, Phat" sort="Voong Vinh, Phat" uniqKey="Voong Vinh P" first="Phat" last="Voong Vinh">Phat Voong Vinh</name>
<affiliation wicri:level="1"><nlm:affiliation>Oxford University Clinical Research Unit, Wellcome Trust Major Overseas Programme, The Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam.</nlm:affiliation>
<country xml:lang="fr">Viêt Nam</country>
<wicri:regionArea>Oxford University Clinical Research Unit, Wellcome Trust Major Overseas Programme, The Hospital for Tropical Diseases, Ho Chi Minh City</wicri:regionArea>
<wicri:noRegion>Ho Chi Minh City</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Vu, Hoan" sort="Vu, Hoan" uniqKey="Vu H" first="Hoan" last="Vu">Hoan Vu</name>
<affiliation wicri:level="1"><nlm:affiliation>Eskitis Institute for Drug Discovery, Griffith University, Nathan, QLD, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Eskitis Institute for Drug Discovery, Griffith University, Nathan, QLD</wicri:regionArea>
<wicri:noRegion>QLD</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Watanabe, Nao Aki" sort="Watanabe, Nao Aki" uniqKey="Watanabe N" first="Nao-Aki" last="Watanabe">Nao-Aki Watanabe</name>
<affiliation wicri:level="1"><nlm:affiliation>Global Health Research Section, hhc Data Creation Center, Eisai Co., Ltd, Tsukuba-shi, Ibaraki, Japan.</nlm:affiliation>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Global Health Research Section, hhc Data Creation Center, Eisai Co., Ltd, Tsukuba-shi, Ibaraki</wicri:regionArea>
<wicri:noRegion>Ibaraki</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Weatherby, Kate" sort="Weatherby, Kate" uniqKey="Weatherby K" first="Kate" last="Weatherby">Kate Weatherby</name>
<affiliation wicri:level="1"><nlm:affiliation>School of Life and Environmental Sciences, University of Sydney, Darlington New South Wales, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>School of Life and Environmental Sciences, University of Sydney, Darlington New South Wales</wicri:regionArea>
<wicri:noRegion>Darlington New South Wales</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="White, Pamela M" sort="White, Pamela M" uniqKey="White P" first="Pamela M" last="White">Pamela M. White</name>
<affiliation wicri:level="2"><nlm:affiliation>Molecular, Cell and Developmental Biology, University of California, Santa Cruz, Santa Cruz, California, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Molecular, Cell and Developmental Biology, University of California, Santa Cruz, Santa Cruz, California</wicri:regionArea>
<placeName><region type="state">Californie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Wilks, Andrew F" sort="Wilks, Andrew F" uniqKey="Wilks A" first="Andrew F" last="Wilks">Andrew F. Wilks</name>
<affiliation wicri:level="1"><nlm:affiliation>Hudson Institute of Medical Research; Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Hudson Institute of Medical Research; Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria</wicri:regionArea>
<wicri:noRegion>Victoria</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Winzeler, Elizabeth A" sort="Winzeler, Elizabeth A" uniqKey="Winzeler E" first="Elizabeth A" last="Winzeler">Elizabeth A. Winzeler</name>
<affiliation wicri:level="2"><nlm:affiliation>Division of Pharmacology and Drug Discovery, Department of Pediatrics, School of Medicine University of California San Diego, La Jolla, California, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Division of Pharmacology and Drug Discovery, Department of Pediatrics, School of Medicine University of California San Diego, La Jolla, California</wicri:regionArea>
<placeName><region type="state">Californie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Wojcik, Edward" sort="Wojcik, Edward" uniqKey="Wojcik E" first="Edward" last="Wojcik">Edward Wojcik</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Biochemistry and Molecular Biology, LSU Health Sciences Center, New Orleans, Louisiana, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Biochemistry and Molecular Biology, LSU Health Sciences Center, New Orleans, Louisiana</wicri:regionArea>
<placeName><region type="state">Louisiane</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Wree, Melanie" sort="Wree, Melanie" uniqKey="Wree M" first="Melanie" last="Wree">Melanie Wree</name>
<affiliation wicri:level="2"><nlm:affiliation>Division of Pharmacology and Drug Discovery, Department of Pediatrics, School of Medicine University of California San Diego, La Jolla, California, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Division of Pharmacology and Drug Discovery, Department of Pediatrics, School of Medicine University of California San Diego, La Jolla, California</wicri:regionArea>
<placeName><region type="state">Californie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Wu, Wesley" sort="Wu, Wesley" uniqKey="Wu W" first="Wesley" last="Wu">Wesley Wu</name>
<affiliation wicri:level="2"><nlm:affiliation>Howard Hughes Medical Institute, Department of Biochemistry and Biophysics, University of California, San Francisco, California, United States of America.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Howard Hughes Medical Institute, Department of Biochemistry and Biophysics, University of California, San Francisco, California</wicri:regionArea>
<placeName><region type="state">Californie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Yokoyama, Naoaki" sort="Yokoyama, Naoaki" uniqKey="Yokoyama N" first="Naoaki" last="Yokoyama">Naoaki Yokoyama</name>
<affiliation wicri:level="1"><nlm:affiliation>National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, Japan.</nlm:affiliation>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido</wicri:regionArea>
<wicri:noRegion>Hokkaido</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Zollo, Paul H A" sort="Zollo, Paul H A" uniqKey="Zollo P" first="Paul H A" last="Zollo">Paul H A. Zollo</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Biochemistry, University of Yaoundé, Yaoundé, Cameroon.</nlm:affiliation>
<country xml:lang="fr">Cameroun</country>
<wicri:regionArea>Department of Biochemistry, University of Yaoundé, Yaoundé</wicri:regionArea>
<wicri:noRegion>Yaoundé</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Abla, Nada" sort="Abla, Nada" uniqKey="Abla N" first="Nada" last="Abla">Nada Abla</name>
<affiliation wicri:level="1"><nlm:affiliation>Medicines for Malaria Venture, Geneva, Switzerland.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Medicines for Malaria Venture, Geneva</wicri:regionArea>
<wicri:noRegion>Geneva</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Blasco, Benjamin" sort="Blasco, Benjamin" uniqKey="Blasco B" first="Benjamin" last="Blasco">Benjamin Blasco</name>
<affiliation wicri:level="1"><nlm:affiliation>Medicines for Malaria Venture, Geneva, Switzerland.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Medicines for Malaria Venture, Geneva</wicri:regionArea>
<wicri:noRegion>Geneva</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Burrows, Jeremy" sort="Burrows, Jeremy" uniqKey="Burrows J" first="Jeremy" last="Burrows">Jeremy Burrows</name>
<affiliation wicri:level="1"><nlm:affiliation>Medicines for Malaria Venture, Geneva, Switzerland.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Medicines for Malaria Venture, Geneva</wicri:regionArea>
<wicri:noRegion>Geneva</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Laleu, Benoit" sort="Laleu, Benoit" uniqKey="Laleu B" first="Benoît" last="Laleu">Benoît Laleu</name>
<affiliation wicri:level="1"><nlm:affiliation>Medicines for Malaria Venture, Geneva, Switzerland.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Medicines for Malaria Venture, Geneva</wicri:regionArea>
<wicri:noRegion>Geneva</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Leroy, Didier" sort="Leroy, Didier" uniqKey="Leroy D" first="Didier" last="Leroy">Didier Leroy</name>
<affiliation wicri:level="1"><nlm:affiliation>Medicines for Malaria Venture, Geneva, Switzerland.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Medicines for Malaria Venture, Geneva</wicri:regionArea>
<wicri:noRegion>Geneva</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Spangenberg, Thomas" sort="Spangenberg, Thomas" uniqKey="Spangenberg T" first="Thomas" last="Spangenberg">Thomas Spangenberg</name>
<affiliation wicri:level="1"><nlm:affiliation>Medicines for Malaria Venture, Geneva, Switzerland.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Medicines for Malaria Venture, Geneva</wicri:regionArea>
<wicri:noRegion>Geneva</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Wells, Timothy" sort="Wells, Timothy" uniqKey="Wells T" first="Timothy" last="Wells">Timothy Wells</name>
<affiliation wicri:level="1"><nlm:affiliation>Medicines for Malaria Venture, Geneva, Switzerland.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Medicines for Malaria Venture, Geneva</wicri:regionArea>
<wicri:noRegion>Geneva</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Willis, Paul A" sort="Willis, Paul A" uniqKey="Willis P" first="Paul A" last="Willis">Paul A. Willis</name>
<affiliation wicri:level="1"><nlm:affiliation>Medicines for Malaria Venture, Geneva, Switzerland.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Medicines for Malaria Venture, Geneva</wicri:regionArea>
<wicri:noRegion>Geneva</wicri:noRegion>
</affiliation>
</author>
</analytic>
<series><title level="j">PLoS pathogens</title>
<idno type="eISSN">1553-7374</idno>
<imprint><date when="2016" type="published">2016</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">A major cause of the paucity of new starting points for drug discovery is the lack of interaction between academia and industry. Much of the global resource in biology is present in universities, whereas the focus of medicinal chemistry is still largely within industry. Open source drug discovery, with sharing of information, is clearly a first step towards overcoming this gap. But the interface could especially be bridged through a scale-up of open sharing of physical compounds, which would accelerate the finding of new starting points for drug discovery. The Medicines for Malaria Venture Malaria Box is a collection of over 400 compounds representing families of structures identified in phenotypic screens of pharmaceutical and academic libraries against the Plasmodium falciparum malaria parasite. The set has now been distributed to almost 200 research groups globally in the last two years, with the only stipulation that information from the screens is deposited in the public domain. This paper reports for the first time on 236 screens that have been carried out against the Malaria Box and compares these results with 55 assays that were previously published, in a format that allows a meta-analysis of the combined dataset. The combined biochemical and cellular assays presented here suggest mechanisms of action for 135 (34%) of the compounds active in killing multiple life-cycle stages of the malaria parasite, including asexual blood, liver, gametocyte, gametes and insect ookinete stages. In addition, many compounds demonstrated activity against other pathogens, showing hits in assays with 16 protozoa, 7 helminths, 9 bacterial and mycobacterial species, the dengue fever mosquito vector, and the NCI60 human cancer cell line panel of 60 human tumor cell lines. Toxicological, pharmacokinetic and metabolic properties were collected on all the compounds, assisting in the selection of the most promising candidates for murine proof-of-concept experiments and medicinal chemistry programs. The data for all of these assays are presented and analyzed to show how outstanding leads for many indications can be selected. These results reveal the immense potential for translating the dispersed expertise in biological assays involving human pathogens into drug discovery starting points, by providing open access to new families of molecules, and emphasize how a small additional investment made to help acquire and distribute compounds, and sharing the data, can catalyze drug discovery for dozens of different indications. Another lesson is that when multiple screens from different groups are run on the same library, results can be integrated quickly to select the most valuable starting points for subsequent medicinal chemistry efforts.</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="In-Data-Review" Owner="NLM"><PMID Version="1">27467575</PMID>
<DateCreated><Year>2016</Year>
<Month>7</Month>
<Day>29</Day>
</DateCreated>
<DateRevised><Year>2016</Year>
<Month>10</Month>
<Day>19</Day>
</DateRevised>
<Article PubModel="Electronic-eCollection"><Journal><ISSN IssnType="Electronic">1553-7374</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>12</Volume>
<Issue>7</Issue>
<PubDate><Year>2016</Year>
<Month>Jul</Month>
</PubDate>
</JournalIssue>
<Title>PLoS pathogens</Title>
<ISOAbbreviation>PLoS Pathog.</ISOAbbreviation>
</Journal>
<ArticleTitle>Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.</ArticleTitle>
<Pagination><MedlinePgn>e1005763</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1371/journal.ppat.1005763</ELocationID>
<Abstract><AbstractText>A major cause of the paucity of new starting points for drug discovery is the lack of interaction between academia and industry. Much of the global resource in biology is present in universities, whereas the focus of medicinal chemistry is still largely within industry. Open source drug discovery, with sharing of information, is clearly a first step towards overcoming this gap. But the interface could especially be bridged through a scale-up of open sharing of physical compounds, which would accelerate the finding of new starting points for drug discovery. The Medicines for Malaria Venture Malaria Box is a collection of over 400 compounds representing families of structures identified in phenotypic screens of pharmaceutical and academic libraries against the Plasmodium falciparum malaria parasite. The set has now been distributed to almost 200 research groups globally in the last two years, with the only stipulation that information from the screens is deposited in the public domain. This paper reports for the first time on 236 screens that have been carried out against the Malaria Box and compares these results with 55 assays that were previously published, in a format that allows a meta-analysis of the combined dataset. The combined biochemical and cellular assays presented here suggest mechanisms of action for 135 (34%) of the compounds active in killing multiple life-cycle stages of the malaria parasite, including asexual blood, liver, gametocyte, gametes and insect ookinete stages. In addition, many compounds demonstrated activity against other pathogens, showing hits in assays with 16 protozoa, 7 helminths, 9 bacterial and mycobacterial species, the dengue fever mosquito vector, and the NCI60 human cancer cell line panel of 60 human tumor cell lines. Toxicological, pharmacokinetic and metabolic properties were collected on all the compounds, assisting in the selection of the most promising candidates for murine proof-of-concept experiments and medicinal chemistry programs. The data for all of these assays are presented and analyzed to show how outstanding leads for many indications can be selected. These results reveal the immense potential for translating the dispersed expertise in biological assays involving human pathogens into drug discovery starting points, by providing open access to new families of molecules, and emphasize how a small additional investment made to help acquire and distribute compounds, and sharing the data, can catalyze drug discovery for dozens of different indications. Another lesson is that when multiple screens from different groups are run on the same library, results can be integrated quickly to select the most valuable starting points for subsequent medicinal chemistry efforts.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Van Voorhis</LastName>
<ForeName>Wesley C</ForeName>
<Initials>WC</Initials>
<AffiliationInfo><Affiliation>Departments of Medicine, Microbiology, and Global Health, Center for Emerging and Re-emerging Infectious Diseases (CERID) University of Washington, Seattle, Washington, United States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Adams</LastName>
<ForeName>John H</ForeName>
<Initials>JH</Initials>
<AffiliationInfo><Affiliation>Center for Global Health and Infectious Diseases Research, Department of Global Health, University of South Florida, Tampa, Florida, United States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Adelfio</LastName>
<ForeName>Roberto</ForeName>
<Initials>R</Initials>
<AffiliationInfo><Affiliation>Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Basel, Switzerland.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>University of Basel, Basel, Switzerland.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Ahyong</LastName>
<ForeName>Vida</ForeName>
<Initials>V</Initials>
<AffiliationInfo><Affiliation>Howard Hughes Medical Institute, Department of Biochemistry and Biophysics, University of California, San Francisco, California, United States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Akabas</LastName>
<ForeName>Myles H</ForeName>
<Initials>MH</Initials>
<AffiliationInfo><Affiliation>Departments of Physiology & Biophysics, Neuroscience and Medicine, Albert Einstein College of Medicine, New York, New York, United States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Alano</LastName>
<ForeName>Pietro</ForeName>
<Initials>P</Initials>
<AffiliationInfo><Affiliation>Dipartimento Malattie Infettive, Parassitarie ed Immunomediate Istituto Superiore di Sanità, Roma, Italia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Alday</LastName>
<ForeName>Aintzane</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>BBD BioPhenix SL-BIOBIDE, Donostia, Gipuzkoa, Spain.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Alemán Resto</LastName>
<ForeName>Yesmalie</ForeName>
<Initials>Y</Initials>
<AffiliationInfo><Affiliation>Bigelow Laboratory for Ocean Sciences, East Boothbay, Maine, United States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Alsibaee</LastName>
<ForeName>Aishah</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland, Dublin, Ireland.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Alzualde</LastName>
<ForeName>Ainhoa</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>BBD BioPhenix SL-BIOBIDE, Donostia, Gipuzkoa, Spain.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Andrews</LastName>
<ForeName>Katherine T</ForeName>
<Initials>KT</Initials>
<AffiliationInfo><Affiliation>Eskitis Institute for Drug Discovery, Griffith University, Nathan, QLD, Australia.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>QIMR Berghofer Medical Research Institute Herston, Brisbane, Australia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Avery</LastName>
<ForeName>Simon V</ForeName>
<Initials>SV</Initials>
<AffiliationInfo><Affiliation>School of Life Sciences, University of Nottingham, Nottingham, Nottinghamshire, England, United Kingdom.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Avery</LastName>
<ForeName>Vicky M</ForeName>
<Initials>VM</Initials>
<AffiliationInfo><Affiliation>Eskitis Institute for Drug Discovery, Griffith University, Nathan, QLD, Australia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Ayong</LastName>
<ForeName>Lawrence</ForeName>
<Initials>L</Initials>
<AffiliationInfo><Affiliation>Institut Pasteur Korea, Pangyo Techno-Valley, Gyeonggi Province, Korea.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Baker</LastName>
<ForeName>Mark</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Clinical Pharmacology, Novartis Consumer Health, Nyon, Switzerland.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Baker</LastName>
<ForeName>Stephen</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>Oxford University Clinical Research Unit, Wellcome Trust Major Overseas Programme, The Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Nuffield Department of Clinical Medicine, Centre for Tropical Medicine, Oxford University, Oxford, England, United Kingdom.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>The London School of Hygiene and Tropical Medicine, London, England, United Kingdom.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Ben Mamoun</LastName>
<ForeName>Choukri</ForeName>
<Initials>C</Initials>
<AffiliationInfo><Affiliation>Internal Medicine, Yale University, New Haven, Connecticut, United States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Bhatia</LastName>
<ForeName>Sangeeta</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>Health Sciences and Technology/Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Bickle</LastName>
<ForeName>Quentin</ForeName>
<Initials>Q</Initials>
<AffiliationInfo><Affiliation>Department of Immunology & Infection, London School of Hygiene and Tropical Medicine, London, England, United Kingdom.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Bounaadja</LastName>
<ForeName>Lotfi</ForeName>
<Initials>L</Initials>
<AffiliationInfo><Affiliation>Museum of National History, Sorbonne Universities, Paris, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Bowling</LastName>
<ForeName>Tana</ForeName>
<Initials>T</Initials>
<AffiliationInfo><Affiliation>SCYNEXIS, Inc., Durham, North Carolina, United States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Bosch</LastName>
<ForeName>Jürgen</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>Department of Biochemistry and Molecular Biology and Johns Hopkins Malaria Research Institute, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, Untied States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Boucher</LastName>
<ForeName>Lauren E</ForeName>
<Initials>LE</Initials>
<AffiliationInfo><Affiliation>Department of Biochemistry and Molecular Biology and Johns Hopkins Malaria Research Institute, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, Untied States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Boyom</LastName>
<ForeName>Fabrice F</ForeName>
<Initials>FF</Initials>
<AffiliationInfo><Affiliation>Department of Biochemistry, University of Yaoundé, Yaoundé, Cameroon.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Brea</LastName>
<ForeName>Jose</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>CIMUS Research Centre, University of Santiago de Compostela, Santiago de Compostela, A Coruña, Spain.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Brennan</LastName>
<ForeName>Marian</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland, Dublin, Ireland.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Burton</LastName>
<ForeName>Audrey</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>SCYNEXIS, Inc., Durham, North Carolina, United States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Caffrey</LastName>
<ForeName>Conor R</ForeName>
<Initials>CR</Initials>
<AffiliationInfo><Affiliation>Center for Discovery and Innovation in Parasitic Diseases, Department of Pathology, University of California San Francisco, San Francisco, California, United States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Camarda</LastName>
<ForeName>Grazia</ForeName>
<Initials>G</Initials>
<AffiliationInfo><Affiliation>Dipartimento Malattie Infettive, Parassitarie ed Immunomediate Istituto Superiore di Sanità, Roma, Italia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Carrasquilla</LastName>
<ForeName>Manuela</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Department of Biochemistry and Molecular Biology and Huck Center for Malaria Research, Pennsylvania State University, University Park, Pennsylvania, United States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Carter</LastName>
<ForeName>Dee</ForeName>
<Initials>D</Initials>
<AffiliationInfo><Affiliation>School of Life and Environmental Sciences, University of Sydney, Darlington New South Wales, Australia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Belen Cassera</LastName>
<ForeName>Maria</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Department of Biochemistry and Virginia Tech Center for Drug Discovery, Virginia Polytechnic Institute and State University, Blacksburg, Virginia, United States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Chih-Chien Cheng</LastName>
<ForeName>Ken</ForeName>
<Initials>K</Initials>
<AffiliationInfo><Affiliation>National Center of Advancing Translational Sciences, NIH, Bethesda, Maryland, United States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Chindaudomsate</LastName>
<ForeName>Worathad</ForeName>
<Initials>W</Initials>
<AffiliationInfo><Affiliation>Department of Biochemistry, Mahidol University, Bangkok, Thailand.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Chubb</LastName>
<ForeName>Anthony</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland, Dublin, Ireland.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Colon</LastName>
<ForeName>Beatrice L</ForeName>
<Initials>BL</Initials>
<AffiliationInfo><Affiliation>Department of Molecular Medicine, Morsani College of Medicine, University of South Florida, Tampa, Florida, United States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Colón-López</LastName>
<ForeName>Daisy D</ForeName>
<Initials>DD</Initials>
<AffiliationInfo><Affiliation>Department of Biochemistry and Molecular Biology and Johns Hopkins Malaria Research Institute, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, Untied States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Corbett</LastName>
<ForeName>Yolanda</ForeName>
<Initials>Y</Initials>
<AffiliationInfo><Affiliation>Department of Pharmacological and Biomolecular Sciences, Università degli Studi di Milano, Milano, Italy.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Crowther</LastName>
<ForeName>Gregory J</ForeName>
<Initials>GJ</Initials>
<AffiliationInfo><Affiliation>Departments of Medicine, Microbiology, and Global Health, Center for Emerging and Re-emerging Infectious Diseases (CERID) University of Washington, Seattle, Washington, United States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Cowan</LastName>
<ForeName>Noemi</ForeName>
<Initials>N</Initials>
<AffiliationInfo><Affiliation>Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Basel, Switzerland.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>University of Basel, Basel, Switzerland.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>D'Alessandro</LastName>
<ForeName>Sarah</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>Department of Pharmacological and Biomolecular Sciences, Università degli Studi di Milano, Milano, Italy.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Le Dang</LastName>
<ForeName>Na</ForeName>
<Initials>N</Initials>
<AffiliationInfo><Affiliation>Department of Pathology and Immunology, Washington University in St Louis, St. Louis, Missouri, United States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Delves</LastName>
<ForeName>Michael</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Department of Life Sciences, Imperial College London, London, England, United Kingdom.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>DeRisi</LastName>
<ForeName>Joseph L</ForeName>
<Initials>JL</Initials>
<Identifier Source="ORCID">http://orcid.org/0000-0002-4611-9205</Identifier>
<AffiliationInfo><Affiliation>Howard Hughes Medical Institute, Department of Biochemistry and Biophysics, University of California, San Francisco, California, United States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Du</LastName>
<ForeName>Alan Y</ForeName>
<Initials>AY</Initials>
<AffiliationInfo><Affiliation>Division of Pharmacology and Drug Discovery, Department of Pediatrics, School of Medicine University of California San Diego, La Jolla, California, United States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Duffy</LastName>
<ForeName>Sandra</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>Eskitis Institute for Drug Discovery, Griffith University, Nathan, QLD, Australia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Abd El-Salam El-Sayed</LastName>
<ForeName>Shimaa</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, Japan.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Department of Biochemistry and Chemistry of nutrition, Mansoura University, Mansoura City, Egypt.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Ferdig</LastName>
<ForeName>Michael T</ForeName>
<Initials>MT</Initials>
<AffiliationInfo><Affiliation>Eck Institute for Global Health, Department of Biological Sciences, University of Notre Dame, Notre Dame Indiana, United States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Fernández Robledo</LastName>
<ForeName>José A</ForeName>
<Initials>JA</Initials>
<AffiliationInfo><Affiliation>Bigelow Laboratory for Ocean Sciences, East Boothbay, Maine, United States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Fidock</LastName>
<ForeName>David A</ForeName>
<Initials>DA</Initials>
<AffiliationInfo><Affiliation>Department of Microbiology & Immunology and Division of Infectious Diseases, Department of Medicine, Columbia University Medical Center, New York, New York, United States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Florent</LastName>
<ForeName>Isabelle</ForeName>
<Initials>I</Initials>
<AffiliationInfo><Affiliation>Museum of National History, Sorbonne Universities, Paris, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Fokou</LastName>
<ForeName>Patrick V T</ForeName>
<Initials>PV</Initials>
<AffiliationInfo><Affiliation>Department of Biochemistry, University of Yaoundé, Yaoundé, Cameroon.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Galstian</LastName>
<ForeName>Ani</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Broad Institute, Cambridge, Massachusetts, United States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Gamo</LastName>
<ForeName>Francisco Javier</ForeName>
<Initials>FJ</Initials>
<AffiliationInfo><Affiliation>Biochemistry and Parasitology Department, Malaria DPU, Diseases of the Developing World (DDW), GlaxoSmithKline R&D, Tres Cantos, Madrid, Spain.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Gokool</LastName>
<ForeName>Suzanne</ForeName>
<Initials>S</Initials>
<Identifier Source="ORCID">http://orcid.org/0000-0002-8451-7044</Identifier>
<AffiliationInfo><Affiliation>Tropical Parasitic Diseases Unit, Northwick Park Institute for Medical Research, Harrow, Middlesex, England, United Kingdom.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Gold</LastName>
<ForeName>Ben</ForeName>
<Initials>B</Initials>
<AffiliationInfo><Affiliation>Department of Microbiology and Immunology, Weill Cornell Medical College, New York, New York, United States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Golub</LastName>
<ForeName>Todd</ForeName>
<Initials>T</Initials>
<AffiliationInfo><Affiliation>Broad Institute, Cambridge, Massachusetts, United States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Goldgof</LastName>
<ForeName>Gregory M</ForeName>
<Initials>GM</Initials>
<AffiliationInfo><Affiliation>Medical Scientist Training Program, University of California, San Diego, San Diego, California, United States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Guha</LastName>
<ForeName>Rajarshi</ForeName>
<Initials>R</Initials>
<AffiliationInfo><Affiliation>National Center of Advancing Translational Sciences, NIH, Bethesda, Maryland, United States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Guiguemde</LastName>
<ForeName>W Armand</ForeName>
<Initials>WA</Initials>
<AffiliationInfo><Affiliation>Department of Chemical Biology & Therapeutics, St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Gural</LastName>
<ForeName>Nil</ForeName>
<Initials>N</Initials>
<AffiliationInfo><Affiliation>Health Sciences and Technology/Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Guy</LastName>
<ForeName>R Kiplin</ForeName>
<Initials>RK</Initials>
<AffiliationInfo><Affiliation>Department of Chemical Biology & Therapeutics, St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Hansen</LastName>
<ForeName>Michael A E</ForeName>
<Initials>MA</Initials>
<AffiliationInfo><Affiliation>Institut Pasteur Korea, Pangyo Techno-Valley, Gyeonggi Province, Korea.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Hanson</LastName>
<ForeName>Kirsten K</ForeName>
<Initials>KK</Initials>
<AffiliationInfo><Affiliation>Dept. of Biology and South Texas Center for Emerging Infectious Diseases, University of Texas, San Antonio, San Antonio, Texas, United States of America.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Instituto de Medicina Molecular, Lisboa, Portugal.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Hemphill</LastName>
<ForeName>Andrew</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Institute of Parasitology, University of Berne, Bern, Switzerland.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Hooft van Huijsduijnen</LastName>
<ForeName>Rob</ForeName>
<Initials>R</Initials>
<AffiliationInfo><Affiliation>Medicines for Malaria Venture, Geneva, Switzerland.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Horii</LastName>
<ForeName>Takaaki</ForeName>
<Initials>T</Initials>
<AffiliationInfo><Affiliation>Global Health Research Section, hhc Data Creation Center, Eisai Co., Ltd, Tsukuba-shi, Ibaraki, Japan.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Horrocks</LastName>
<ForeName>Paul</ForeName>
<Initials>P</Initials>
<AffiliationInfo><Affiliation>Institute for Science and Technology in Medicine, Keele University, Keele, Staffordshire, United Kingdom.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Hughes</LastName>
<ForeName>Tyler B</ForeName>
<Initials>TB</Initials>
<AffiliationInfo><Affiliation>Department of Pathology and Immunology, Washington University in St Louis, St. Louis, Missouri, United States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Huston</LastName>
<ForeName>Christopher</ForeName>
<Initials>C</Initials>
<AffiliationInfo><Affiliation>Department of Medicine, College of Medicine, University of Vermont, Burlington, Vermont, United States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Igarashi</LastName>
<ForeName>Ikuo</ForeName>
<Initials>I</Initials>
<AffiliationInfo><Affiliation>National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, Japan.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Ingram-Sieber</LastName>
<ForeName>Katrin</ForeName>
<Initials>K</Initials>
<AffiliationInfo><Affiliation>Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Basel, Switzerland.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>University of Basel, Basel, Switzerland.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Itoe</LastName>
<ForeName>Maurice A</ForeName>
<Initials>MA</Initials>
<AffiliationInfo><Affiliation>Instituto de Medicina Molecular, Lisboa, Portugal.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Jadhav</LastName>
<ForeName>Ajit</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>National Center of Advancing Translational Sciences, NIH, Bethesda, Maryland, United States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Naranuntarat Jensen</LastName>
<ForeName>Amornrat</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Department of Pathobiology, Faculty of Science, Mahidol University, Bangkok Thailand.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Jensen</LastName>
<ForeName>Laran T</ForeName>
<Initials>LT</Initials>
<AffiliationInfo><Affiliation>Department of Biochemistry, Mahidol University, Bangkok, Thailand.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Jiang</LastName>
<ForeName>Rays H Y</ForeName>
<Initials>RH</Initials>
<AffiliationInfo><Affiliation>Center for Global Health and Infectious Diseases Research, Department of Global Health, University of South Florida, Tampa, Florida, United States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Kaiser</LastName>
<ForeName>Annette</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Medical Research Centre, Institute for Pharmacogenetics, Essen, Germany.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Keiser</LastName>
<ForeName>Jennifer</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Basel, Switzerland.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>University of Basel, Basel, Switzerland.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Ketas</LastName>
<ForeName>Thomas</ForeName>
<Initials>T</Initials>
<AffiliationInfo><Affiliation>Department of Microbiology and Immunology, Weill Cornell Medical College, New York, New York, United States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Kicka</LastName>
<ForeName>Sebastien</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>Department of Biochemistry, University of Geneva, Geneva, Switzerland.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Kim</LastName>
<ForeName>Sunyoung</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>Department of Biochemistry and Molecular Biology, LSU Health Sciences Center, New Orleans, Louisiana, United States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Kirk</LastName>
<ForeName>Kiaran</ForeName>
<Initials>K</Initials>
<AffiliationInfo><Affiliation>Research School of Biology, Australian National University, Canberra, Australian Capital Territory, Australia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Kumar</LastName>
<ForeName>Vidya P</ForeName>
<Initials>VP</Initials>
<AffiliationInfo><Affiliation>Internal Medicine, Yale University, New Haven, Connecticut, United States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Kyle</LastName>
<ForeName>Dennis E</ForeName>
<Initials>DE</Initials>
<AffiliationInfo><Affiliation>Center for Global Health and Infectious Diseases Research, Department of Global Health, University of South Florida, Tampa, Florida, United States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Lafuente</LastName>
<ForeName>Maria Jose</ForeName>
<Initials>MJ</Initials>
<AffiliationInfo><Affiliation>Biochemistry and Parasitology Department, Malaria DPU, Diseases of the Developing World (DDW), GlaxoSmithKline R&D, Tres Cantos, Madrid, Spain.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Landfear</LastName>
<ForeName>Scott</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>Department of Molecular Microbiology & Immunology, Oregon Health & Science University, Portland, Oregon, United States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Lee</LastName>
<ForeName>Nathan</ForeName>
<Initials>N</Initials>
<AffiliationInfo><Affiliation>Medicines for Malaria Venture, Geneva, Switzerland.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Lee</LastName>
<ForeName>Sukjun</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>Institut Pasteur Korea, Pangyo Techno-Valley, Gyeonggi Province, Korea.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Lehane</LastName>
<ForeName>Adele M</ForeName>
<Initials>AM</Initials>
<AffiliationInfo><Affiliation>Research School of Biology, Australian National University, Canberra, Australian Capital Territory, Australia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Li</LastName>
<ForeName>Fengwu</ForeName>
<Initials>F</Initials>
<AffiliationInfo><Affiliation>Department of Molecular Microbiology & Immunology, Oregon Health & Science University, Portland, Oregon, United States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Little</LastName>
<ForeName>David</ForeName>
<Initials>D</Initials>
<AffiliationInfo><Affiliation>Department of Microbiology and Immunology, Weill Cornell Medical College, New York, New York, United States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Liu</LastName>
<ForeName>Liqiong</ForeName>
<Initials>L</Initials>
<AffiliationInfo><Affiliation>Department of Biochemistry and Molecular Biology, LSU Health Sciences Center, New Orleans, Louisiana, United States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Llinás</LastName>
<ForeName>Manuel</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Department of Biochemistry and Molecular Biology and Huck Center for Malaria Research, Pennsylvania State University, University Park, Pennsylvania, United States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Loza</LastName>
<ForeName>Maria I</ForeName>
<Initials>MI</Initials>
<AffiliationInfo><Affiliation>CIMUS Research Centre, University of Santiago de Compostela, Santiago de Compostela, A Coruña, Spain.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Lubar</LastName>
<ForeName>Aristea</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Department of Medicine, University of California San Diego, San Diego, California, United States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Lucantoni</LastName>
<ForeName>Leonardo</ForeName>
<Initials>L</Initials>
<AffiliationInfo><Affiliation>Eskitis Institute for Drug Discovery, Griffith University, Nathan, QLD, Australia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Lucet</LastName>
<ForeName>Isabelle</ForeName>
<Initials>I</Initials>
<AffiliationInfo><Affiliation>Department of Biochemistry and Molecular Biology, Monash University, Clayton, Australia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Maes</LastName>
<ForeName>Louis</ForeName>
<Initials>L</Initials>
<AffiliationInfo><Affiliation>University of Antwerp, Department of Biomedical Sciences, Antwerp, Belgium.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Mancama</LastName>
<ForeName>Dalu</ForeName>
<Initials>D</Initials>
<AffiliationInfo><Affiliation>Biosciences Unit, Council for Scientific and Industrial Research, Pretoria, South Africa.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Mansour</LastName>
<ForeName>Nuha R</ForeName>
<Initials>NR</Initials>
<AffiliationInfo><Affiliation>Department of Immunology & Infection, London School of Hygiene and Tropical Medicine, London, England, United Kingdom.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>March</LastName>
<ForeName>Sandra</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>Health Sciences and Technology/Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>McGowan</LastName>
<ForeName>Sheena</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>Department of Microbiology, Monash University, Clayton, Australia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Medina Vera</LastName>
<ForeName>Iset</ForeName>
<Initials>I</Initials>
<AffiliationInfo><Affiliation>Instituto de Medicina Molecular, Lisboa, Portugal.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Meister</LastName>
<ForeName>Stephan</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>Division of Pharmacology and Drug Discovery, Department of Pediatrics, School of Medicine University of California San Diego, La Jolla, California, United States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Mercer</LastName>
<ForeName>Luke</ForeName>
<Initials>L</Initials>
<AffiliationInfo><Affiliation>SCYNEXIS, Inc., Durham, North Carolina, United States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Mestres</LastName>
<ForeName>Jordi</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>Chemotargets S.L. and Research Group on Systems Pharmacology, Research Program on Biomedical Informatics (GRIB), IMIM Hospital del Mar Institute of Medical Research and University Pompeu Fabra, Barcelona, Catalonia, Spain.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Mfopa</LastName>
<ForeName>Alvine N</ForeName>
<Initials>AN</Initials>
<AffiliationInfo><Affiliation>Department of Biochemistry, University of Yaoundé, Yaoundé, Cameroon.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Misra</LastName>
<ForeName>Raj N</ForeName>
<Initials>RN</Initials>
<AffiliationInfo><Affiliation>Division of Cancer Therapeutics and Diagnosis, Drug Synthesis and Chemistry Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Moon</LastName>
<ForeName>Seunghyun</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>Institut Pasteur Korea, Pangyo Techno-Valley, Gyeonggi Province, Korea.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Moore</LastName>
<ForeName>John P</ForeName>
<Initials>JP</Initials>
<AffiliationInfo><Affiliation>Department of Microbiology and Immunology, Weill Cornell Medical College, New York, New York, United States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Morais Rodrigues da Costa</LastName>
<ForeName>Francielly</ForeName>
<Initials>F</Initials>
<AffiliationInfo><Affiliation>Graduate Program in Bioinformatics, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Müller</LastName>
<ForeName>Joachim</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>Institute of Parasitology, University of Berne, Bern, Switzerland.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Muriana</LastName>
<ForeName>Arantza</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>BBD BioPhenix SL-BIOBIDE, Donostia, Gipuzkoa, Spain.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Nakazawa Hewitt</LastName>
<ForeName>Stephen</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>Departments of Medicine, Microbiology, and Global Health, Center for Emerging and Re-emerging Infectious Diseases (CERID) University of Washington, Seattle, Washington, United States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Nare</LastName>
<ForeName>Bakela</ForeName>
<Initials>B</Initials>
<AffiliationInfo><Affiliation>SCYNEXIS, Inc., Durham, North Carolina, United States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Nathan</LastName>
<ForeName>Carl</ForeName>
<Initials>C</Initials>
<AffiliationInfo><Affiliation>Department of Microbiology and Immunology, Weill Cornell Medical College, New York, New York, United States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Narraidoo</LastName>
<ForeName>Nathalie</ForeName>
<Initials>N</Initials>
<AffiliationInfo><Affiliation>School of Life Sciences, University of Nottingham, Nottingham, Nottinghamshire, England, United Kingdom.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Nawaratna</LastName>
<ForeName>Sujeevi</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>Eskitis Institute for Drug Discovery, Griffith University, Nathan, QLD, Australia.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>QIMR Berghofer Medical Research Institute Herston, Brisbane, Australia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Ojo</LastName>
<ForeName>Kayode K</ForeName>
<Initials>KK</Initials>
<AffiliationInfo><Affiliation>Departments of Medicine, Microbiology, and Global Health, Center for Emerging and Re-emerging Infectious Diseases (CERID) University of Washington, Seattle, Washington, United States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Ortiz</LastName>
<ForeName>Diana</ForeName>
<Initials>D</Initials>
<AffiliationInfo><Affiliation>Department of Molecular Microbiology & Immunology, Oregon Health & Science University, Portland, Oregon, United States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Panic</LastName>
<ForeName>Gordana</ForeName>
<Initials>G</Initials>
<AffiliationInfo><Affiliation>Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Basel, Switzerland.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>University of Basel, Basel, Switzerland.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Papadatos</LastName>
<ForeName>George</ForeName>
<Initials>G</Initials>
<AffiliationInfo><Affiliation>ChEMBL group, European Molecular Biology Laboratory-European Bioinformatics Institute (EMBL-EBI), Hinxton, Cambridgeshire, United Kingdom.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Parapini</LastName>
<ForeName>Silvia</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>Department of Pharmacological and Biomolecular Sciences, Università degli Studi di Milano, Milano, Italy.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Patra</LastName>
<ForeName>Kailash</ForeName>
<Initials>K</Initials>
<AffiliationInfo><Affiliation>Department of Medicine, University of California San Diego, San Diego, California, United States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Pham</LastName>
<ForeName>Ngoc</ForeName>
<Initials>N</Initials>
<AffiliationInfo><Affiliation>Eskitis Institute for Drug Discovery, Griffith University, Nathan, QLD, Australia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Prats</LastName>
<ForeName>Sarah</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>Biochemistry and Parasitology Department, Malaria DPU, Diseases of the Developing World (DDW), GlaxoSmithKline R&D, Tres Cantos, Madrid, Spain.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Plouffe</LastName>
<ForeName>David M</ForeName>
<Initials>DM</Initials>
<AffiliationInfo><Affiliation>Genomics Institute of the Novartis Research Foundation, San Diego, California, United States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Poulsen</LastName>
<ForeName>Sally-Ann</ForeName>
<Initials>SA</Initials>
<AffiliationInfo><Affiliation>Eskitis Institute for Drug Discovery, Griffith University, Nathan, QLD, Australia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Pradhan</LastName>
<ForeName>Anupam</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Center for Global Health and Infectious Diseases Research, Department of Global Health, University of South Florida, Tampa, Florida, United States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Quevedo</LastName>
<ForeName>Celia</ForeName>
<Initials>C</Initials>
<AffiliationInfo><Affiliation>BBD BioPhenix SL-BIOBIDE, Donostia, Gipuzkoa, Spain.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Quinn</LastName>
<ForeName>Ronald J</ForeName>
<Initials>RJ</Initials>
<AffiliationInfo><Affiliation>Eskitis Institute for Drug Discovery, Griffith University, Nathan, QLD, Australia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Rice</LastName>
<ForeName>Christopher A</ForeName>
<Initials>CA</Initials>
<AffiliationInfo><Affiliation>Center for Global Health and Infectious Diseases Research, Department of Global Health, University of South Florida, Tampa, Florida, United States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Abdo Rizk</LastName>
<ForeName>Mohamed</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, Japan.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Department of Internal Medicine and Infectious Diseases, Faculty of Veterinary Medicine, Mansoura University, Mansoura City, Egypt.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Ruecker</LastName>
<ForeName>Andrea</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Department of Life Sciences, Imperial College London, London, England, United Kingdom.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>St Onge</LastName>
<ForeName>Robert</ForeName>
<Initials>R</Initials>
<AffiliationInfo><Affiliation>Department of Biochemistry and Stanford Genome Technology Center, Stanford University, Palo Alto, Calilfornia, United States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Salgado Ferreira</LastName>
<ForeName>Rafaela</ForeName>
<Initials>R</Initials>
<AffiliationInfo><Affiliation>Departamento de Bioquímica e Imunologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Samra</LastName>
<ForeName>Jasmeet</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>Department of Biochemistry and Molecular Biology and Huck Center for Malaria Research, Pennsylvania State University, University Park, Pennsylvania, United States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Robinett</LastName>
<ForeName>Natalie G</ForeName>
<Initials>NG</Initials>
<AffiliationInfo><Affiliation>Department of Biochemistry and Molecular Biology and Johns Hopkins Malaria Research Institute, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, Untied States of America.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Laboratoire de Chimie Moléculaire, CNRS,-UMR 7509, COB-IRJBD, Mulhouse Cedex, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Schlecht</LastName>
<ForeName>Ulrich</ForeName>
<Initials>U</Initials>
<AffiliationInfo><Affiliation>Department of Biochemistry and Stanford Genome Technology Center, Stanford University, Palo Alto, Calilfornia, United States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Schmitt</LastName>
<ForeName>Marjorie</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Laboratoire de Chimie Moléculaire, CNRS,-UMR 7509, COB-IRJBD, Mulhouse Cedex, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Silva Villela</LastName>
<ForeName>Filipe</ForeName>
<Initials>F</Initials>
<AffiliationInfo><Affiliation>Departamento de Bioquímica e Imunologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Silvestrini</LastName>
<ForeName>Francesco</ForeName>
<Initials>F</Initials>
<AffiliationInfo><Affiliation>Dipartimento Malattie Infettive, Parassitarie ed Immunomediate Istituto Superiore di Sanità, Roma, Italia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Sinden</LastName>
<ForeName>Robert</ForeName>
<Initials>R</Initials>
<AffiliationInfo><Affiliation>The Jenner Institute, University of Oxford, Oxford, England, United Kingdom.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Smith</LastName>
<ForeName>Dennis A</ForeName>
<Initials>DA</Initials>
<AffiliationInfo><Affiliation>Department of Chemistry, University of Capetown, Capetown, South Africa.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Soldati</LastName>
<ForeName>Thierry</ForeName>
<Initials>T</Initials>
<AffiliationInfo><Affiliation>Department of Biochemistry, University of Geneva, Geneva, Switzerland.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Spitzmüller</LastName>
<ForeName>Andreas</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Chemotargets S.L. and Research Group on Systems Pharmacology, Research Program on Biomedical Informatics (GRIB), IMIM Hospital del Mar Institute of Medical Research and University Pompeu Fabra, Barcelona, Catalonia, Spain.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Stamm</LastName>
<ForeName>Serge Maximilian</ForeName>
<Initials>SM</Initials>
<AffiliationInfo><Affiliation>Department of Biochemistry and Molecular Biology and Johns Hopkins Malaria Research Institute, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, Untied States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Sullivan</LastName>
<ForeName>David J</ForeName>
<Initials>DJ</Initials>
<AffiliationInfo><Affiliation>H. Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins School of Public Health, Baltimore, Maryland, United States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Sullivan</LastName>
<ForeName>William</ForeName>
<Initials>W</Initials>
<AffiliationInfo><Affiliation>Molecular, Cell and Developmental Biology, University of California, Santa Cruz, Santa Cruz, California, United States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Suresh</LastName>
<ForeName>Sundari</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>Departamento de Bioquímica e Imunologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Suzuki</LastName>
<ForeName>Brian M</ForeName>
<Initials>BM</Initials>
<AffiliationInfo><Affiliation>Center for Discovery and Innovation in Parasitic Diseases, Department of Pathology, University of California San Francisco, San Francisco, California, United States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Suzuki</LastName>
<ForeName>Yo</ForeName>
<Initials>Y</Initials>
<AffiliationInfo><Affiliation>Department of Synthetic Biology and Bioenergy, J. Craig Venter Institute, La Jolla, California, United States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Swamidass</LastName>
<ForeName>S Joshua</ForeName>
<Initials>SJ</Initials>
<AffiliationInfo><Affiliation>Department of Life Sciences, Imperial College London, London, England, United Kingdom.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Taramelli</LastName>
<ForeName>Donatella</ForeName>
<Initials>D</Initials>
<AffiliationInfo><Affiliation>Department of Pathology and Immunology, Washington University in St Louis, St. Louis, Missouri, United States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Tchokouaha</LastName>
<ForeName>Lauve R Y</ForeName>
<Initials>LR</Initials>
<AffiliationInfo><Affiliation>Department of Biochemistry, University of Yaoundé, Yaoundé, Cameroon.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Theron</LastName>
<ForeName>Anjo</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Biosciences Unit, Council for Scientific and Industrial Research, Pretoria, South Africa.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Thomas</LastName>
<ForeName>David</ForeName>
<Initials>D</Initials>
<AffiliationInfo><Affiliation>Broad Institute, Cambridge, Massachusetts, United States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Tonissen</LastName>
<ForeName>Kathryn F</ForeName>
<Initials>KF</Initials>
<AffiliationInfo><Affiliation>Eskitis Institute for Drug Discovery, Griffith University, Nathan, QLD, Australia.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>School of Natural Sciences, Griffith University, Nathan, Queensland, Australia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Townson</LastName>
<ForeName>Simon</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>Tropical Parasitic Diseases Unit, Northwick Park Institute for Medical Research, Harrow, Middlesex, England, United Kingdom.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Tripathi</LastName>
<ForeName>Abhai K</ForeName>
<Initials>AK</Initials>
<AffiliationInfo><Affiliation>H. Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins School of Public Health, Baltimore, Maryland, United States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Trofimov</LastName>
<ForeName>Valentin</ForeName>
<Initials>V</Initials>
<AffiliationInfo><Affiliation>Department of Biochemistry, University of Geneva, Geneva, Switzerland.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Udenze</LastName>
<ForeName>Kenneth O</ForeName>
<Initials>KO</Initials>
<AffiliationInfo><Affiliation>Center for Global Health and Infectious Diseases Research, Department of Global Health, University of South Florida, Tampa, Florida, United States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Ullah</LastName>
<ForeName>Imran</ForeName>
<Initials>I</Initials>
<AffiliationInfo><Affiliation>Institute for Science and Technology in Medicine, Keele University, Keele, Staffordshire, United Kingdom.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Vallieres</LastName>
<ForeName>Cindy</ForeName>
<Initials>C</Initials>
<AffiliationInfo><Affiliation>School of Life Sciences, University of Nottingham, Nottingham, Nottinghamshire, England, United Kingdom.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Vigil</LastName>
<ForeName>Edgar</ForeName>
<Initials>E</Initials>
<AffiliationInfo><Affiliation>Division of Pharmacology and Drug Discovery, Department of Pediatrics, School of Medicine University of California San Diego, La Jolla, California, United States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Vinetz</LastName>
<ForeName>Joseph M</ForeName>
<Initials>JM</Initials>
<AffiliationInfo><Affiliation>Department of Medicine, University of California San Diego, San Diego, California, United States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Voong Vinh</LastName>
<ForeName>Phat</ForeName>
<Initials>P</Initials>
<AffiliationInfo><Affiliation>Oxford University Clinical Research Unit, Wellcome Trust Major Overseas Programme, The Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Vu</LastName>
<ForeName>Hoan</ForeName>
<Initials>H</Initials>
<AffiliationInfo><Affiliation>Eskitis Institute for Drug Discovery, Griffith University, Nathan, QLD, Australia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Watanabe</LastName>
<ForeName>Nao-Aki</ForeName>
<Initials>NA</Initials>
<AffiliationInfo><Affiliation>Global Health Research Section, hhc Data Creation Center, Eisai Co., Ltd, Tsukuba-shi, Ibaraki, Japan.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Weatherby</LastName>
<ForeName>Kate</ForeName>
<Initials>K</Initials>
<AffiliationInfo><Affiliation>School of Life and Environmental Sciences, University of Sydney, Darlington New South Wales, Australia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>White</LastName>
<ForeName>Pamela M</ForeName>
<Initials>PM</Initials>
<AffiliationInfo><Affiliation>Molecular, Cell and Developmental Biology, University of California, Santa Cruz, Santa Cruz, California, United States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Wilks</LastName>
<ForeName>Andrew F</ForeName>
<Initials>AF</Initials>
<AffiliationInfo><Affiliation>Hudson Institute of Medical Research; Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>SYNthesis Research, Parkville, Victoria, Australia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Winzeler</LastName>
<ForeName>Elizabeth A</ForeName>
<Initials>EA</Initials>
<AffiliationInfo><Affiliation>Division of Pharmacology and Drug Discovery, Department of Pediatrics, School of Medicine University of California San Diego, La Jolla, California, United States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Wojcik</LastName>
<ForeName>Edward</ForeName>
<Initials>E</Initials>
<AffiliationInfo><Affiliation>Department of Biochemistry and Molecular Biology, LSU Health Sciences Center, New Orleans, Louisiana, United States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Wree</LastName>
<ForeName>Melanie</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Division of Pharmacology and Drug Discovery, Department of Pediatrics, School of Medicine University of California San Diego, La Jolla, California, United States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Wu</LastName>
<ForeName>Wesley</ForeName>
<Initials>W</Initials>
<AffiliationInfo><Affiliation>Howard Hughes Medical Institute, Department of Biochemistry and Biophysics, University of California, San Francisco, California, United States of America.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Yokoyama</LastName>
<ForeName>Naoaki</ForeName>
<Initials>N</Initials>
<AffiliationInfo><Affiliation>National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, Japan.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Zollo</LastName>
<ForeName>Paul H A</ForeName>
<Initials>PH</Initials>
<AffiliationInfo><Affiliation>Department of Biochemistry, University of Yaoundé, Yaoundé, Cameroon.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Abla</LastName>
<ForeName>Nada</ForeName>
<Initials>N</Initials>
<AffiliationInfo><Affiliation>Medicines for Malaria Venture, Geneva, Switzerland.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Blasco</LastName>
<ForeName>Benjamin</ForeName>
<Initials>B</Initials>
<AffiliationInfo><Affiliation>Medicines for Malaria Venture, Geneva, Switzerland.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Burrows</LastName>
<ForeName>Jeremy</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>Medicines for Malaria Venture, Geneva, Switzerland.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Laleu</LastName>
<ForeName>Benoît</ForeName>
<Initials>B</Initials>
<AffiliationInfo><Affiliation>Medicines for Malaria Venture, Geneva, Switzerland.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Leroy</LastName>
<ForeName>Didier</ForeName>
<Initials>D</Initials>
<AffiliationInfo><Affiliation>Medicines for Malaria Venture, Geneva, Switzerland.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Spangenberg</LastName>
<ForeName>Thomas</ForeName>
<Initials>T</Initials>
<AffiliationInfo><Affiliation>Medicines for Malaria Venture, Geneva, Switzerland.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Wells</LastName>
<ForeName>Timothy</ForeName>
<Initials>T</Initials>
<AffiliationInfo><Affiliation>Medicines for Malaria Venture, Geneva, Switzerland.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Willis</LastName>
<ForeName>Paul A</ForeName>
<Initials>PA</Initials>
<AffiliationInfo><Affiliation>Medicines for Malaria Venture, Geneva, Switzerland.</Affiliation>
</AffiliationInfo>
</Author>
</AuthorList>
<Language>ENG</Language>
<GrantList CompleteYN="Y"><Grant><GrantID>R01 GM097350</GrantID>
<Acronym>GM</Acronym>
<Agency>NIGMS NIH HHS</Agency>
<Country>United States</Country>
</Grant>
<Grant><GrantID>T32 GM007198</GrantID>
<Acronym>GM</Acronym>
<Agency>NIGMS NIH HHS</Agency>
<Country>United States</Country>
</Grant>
</GrantList>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
</PublicationTypeList>
<ArticleDate DateType="Electronic"><Year>2016</Year>
<Month>Jul</Month>
<Day>28</Day>
</ArticleDate>
</Article>
<MedlineJournalInfo><Country>United States</Country>
<MedlineTA>PLoS Pathog</MedlineTA>
<NlmUniqueID>101238921</NlmUniqueID>
<ISSNLinking>1553-7366</ISSNLinking>
</MedlineJournalInfo>
<CitationSubset>IM</CitationSubset>
<OtherID Source="NLM">PMC4965013</OtherID>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="received"><Year>2016</Year>
<Month>4</Month>
<Day>1</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="accepted"><Year>2016</Year>
<Month>6</Month>
<Day>21</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="entrez"><Year>2016</Year>
<Month>7</Month>
<Day>29</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="pubmed"><Year>2016</Year>
<Month>7</Month>
<Day>29</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline"><Year>2016</Year>
<Month>7</Month>
<Day>29</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
</History>
<PublicationStatus>epublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">27467575</ArticleId>
<ArticleId IdType="doi">10.1371/journal.ppat.1005763</ArticleId>
<ArticleId IdType="pii">PPATHOGENS-D-16-00679</ArticleId>
<ArticleId IdType="pmc">PMC4965013</ArticleId>
</ArticleIdList>
</PubmedData>
</pubmed>
<affiliations><list><country><li>Afrique du Sud</li>
<li>Allemagne</li>
<li>Australie</li>
<li>Belgique</li>
<li>Brésil</li>
<li>Cameroun</li>
<li>Corée du Sud</li>
<li>Espagne</li>
<li>France</li>
<li>Irlande (pays)</li>
<li>Italie</li>
<li>Japon</li>
<li>Portugal</li>
<li>Royaume-Uni</li>
<li>Suisse</li>
<li>Thaïlande</li>
<li>Viêt Nam</li>
<li>États-Unis</li>
</country>
<region><li>Angleterre</li>
<li>Californie</li>
<li>Canton de Berne</li>
<li>Canton de Genève</li>
<li>Caroline du Nord</li>
<li>Communauté de Madrid</li>
<li>Connecticut</li>
<li>Floride</li>
<li>Galice</li>
<li>Latium</li>
<li>Louisiane</li>
<li>Maine (État)</li>
<li>Maryland</li>
<li>Massachusetts</li>
<li>Minas Gerais</li>
<li>Missouri (État)</li>
<li>Nottinghamshire</li>
<li>Oregon</li>
<li>Oxfordshire</li>
<li>Pennsylvanie</li>
<li>Province d'Anvers</li>
<li>Tennessee</li>
<li>Texas</li>
<li>Vermont</li>
<li>Virginie</li>
<li>Washington (État)</li>
<li>État de New York</li>
</region>
<settlement><li>Anvers</li>
<li>Belo Horizonte</li>
<li>Berne</li>
<li>Genève</li>
<li>Madrid</li>
<li>Nottingham</li>
<li>Oxford</li>
<li>Paris</li>
<li>Portland</li>
<li>Rome</li>
<li>Saint-Louis (Missouri)</li>
<li>Santiago de Compostela</li>
<li>Seattle</li>
<li>Tampa</li>
<li>University Park (Pennsylvanie)</li>
</settlement>
<orgName><li>Université Washington de Saint-Louis</li>
<li>Université d'Anvers</li>
<li>Université d'Oxford</li>
<li>Université d'État de Pennsylvanie</li>
<li>Université de Floride du Sud</li>
<li>Université de Genève</li>
<li>Université de Nottingham</li>
<li>Université de Saint-Jacques-de-Compostelle</li>
<li>Université de Washington</li>
<li>Université des sciences et de la médecine de l'Oregon</li>
<li>Université fédérale du Minas Gerais</li>
</orgName>
</list>
<tree><noCountry><name sortKey="Bosch, Jurgen" sort="Bosch, Jurgen" uniqKey="Bosch J" first="Jürgen" last="Bosch">Jürgen Bosch</name>
<name sortKey="Boucher, Lauren E" sort="Boucher, Lauren E" uniqKey="Boucher L" first="Lauren E" last="Boucher">Lauren E. Boucher</name>
<name sortKey="Col N L Pez, Daisy D" sort="Col N L Pez, Daisy D" uniqKey="Col N L Pez D" first="Daisy D" last="Col N-L Pez">Daisy D. Col N-L Pez</name>
<name sortKey="Naranuntarat Jensen, Amornrat" sort="Naranuntarat Jensen, Amornrat" uniqKey="Naranuntarat Jensen A" first="Amornrat" last="Naranuntarat Jensen">Amornrat Naranuntarat Jensen</name>
<name sortKey="Robinett, Natalie G" sort="Robinett, Natalie G" uniqKey="Robinett N" first="Natalie G" last="Robinett">Natalie G. Robinett</name>
<name sortKey="Stamm, Serge Maximilian" sort="Stamm, Serge Maximilian" uniqKey="Stamm S" first="Serge Maximilian" last="Stamm">Serge Maximilian Stamm</name>
</noCountry>
<country name="États-Unis"><region name="Washington (État)"><name sortKey="Van Voorhis, Wesley C" sort="Van Voorhis, Wesley C" uniqKey="Van Voorhis W" first="Wesley C" last="Van Voorhis">Wesley C. Van Voorhis</name>
</region>
<name sortKey="Adams, John H" sort="Adams, John H" uniqKey="Adams J" first="John H" last="Adams">John H. Adams</name>
<name sortKey="Ahyong, Vida" sort="Ahyong, Vida" uniqKey="Ahyong V" first="Vida" last="Ahyong">Vida Ahyong</name>
<name sortKey="Akabas, Myles H" sort="Akabas, Myles H" uniqKey="Akabas M" first="Myles H" last="Akabas">Myles H. Akabas</name>
<name sortKey="Aleman Resto, Yesmalie" sort="Aleman Resto, Yesmalie" uniqKey="Aleman Resto Y" first="Yesmalie" last="Alemán Resto">Yesmalie Alemán Resto</name>
<name sortKey="Belen Cassera, Maria" sort="Belen Cassera, Maria" uniqKey="Belen Cassera M" first="Maria" last="Belen Cassera">Maria Belen Cassera</name>
<name sortKey="Ben Mamoun, Choukri" sort="Ben Mamoun, Choukri" uniqKey="Ben Mamoun C" first="Choukri" last="Ben Mamoun">Choukri Ben Mamoun</name>
<name sortKey="Bhatia, Sangeeta" sort="Bhatia, Sangeeta" uniqKey="Bhatia S" first="Sangeeta" last="Bhatia">Sangeeta Bhatia</name>
<name sortKey="Bowling, Tana" sort="Bowling, Tana" uniqKey="Bowling T" first="Tana" last="Bowling">Tana Bowling</name>
<name sortKey="Burton, Audrey" sort="Burton, Audrey" uniqKey="Burton A" first="Audrey" last="Burton">Audrey Burton</name>
<name sortKey="Caffrey, Conor R" sort="Caffrey, Conor R" uniqKey="Caffrey C" first="Conor R" last="Caffrey">Conor R. Caffrey</name>
<name sortKey="Carrasquilla, Manuela" sort="Carrasquilla, Manuela" uniqKey="Carrasquilla M" first="Manuela" last="Carrasquilla">Manuela Carrasquilla</name>
<name sortKey="Chih Chien Cheng, Ken" sort="Chih Chien Cheng, Ken" uniqKey="Chih Chien Cheng K" first="Ken" last="Chih-Chien Cheng">Ken Chih-Chien Cheng</name>
<name sortKey="Colon, Beatrice L" sort="Colon, Beatrice L" uniqKey="Colon B" first="Beatrice L" last="Colon">Beatrice L. Colon</name>
<name sortKey="Crowther, Gregory J" sort="Crowther, Gregory J" uniqKey="Crowther G" first="Gregory J" last="Crowther">Gregory J. Crowther</name>
<name sortKey="Derisi, Joseph L" sort="Derisi, Joseph L" uniqKey="Derisi J" first="Joseph L" last="Derisi">Joseph L. Derisi</name>
<name sortKey="Du, Alan Y" sort="Du, Alan Y" uniqKey="Du A" first="Alan Y" last="Du">Alan Y. Du</name>
<name sortKey="Ferdig, Michael T" sort="Ferdig, Michael T" uniqKey="Ferdig M" first="Michael T" last="Ferdig">Michael T. Ferdig</name>
<name sortKey="Fernandez Robledo, Jose A" sort="Fernandez Robledo, Jose A" uniqKey="Fernandez Robledo J" first="José A" last="Fernández Robledo">José A. Fernández Robledo</name>
<name sortKey="Fidock, David A" sort="Fidock, David A" uniqKey="Fidock D" first="David A" last="Fidock">David A. Fidock</name>
<name sortKey="Galstian, Ani" sort="Galstian, Ani" uniqKey="Galstian A" first="Ani" last="Galstian">Ani Galstian</name>
<name sortKey="Gold, Ben" sort="Gold, Ben" uniqKey="Gold B" first="Ben" last="Gold">Ben Gold</name>
<name sortKey="Goldgof, Gregory M" sort="Goldgof, Gregory M" uniqKey="Goldgof G" first="Gregory M" last="Goldgof">Gregory M. Goldgof</name>
<name sortKey="Golub, Todd" sort="Golub, Todd" uniqKey="Golub T" first="Todd" last="Golub">Todd Golub</name>
<name sortKey="Guha, Rajarshi" sort="Guha, Rajarshi" uniqKey="Guha R" first="Rajarshi" last="Guha">Rajarshi Guha</name>
<name sortKey="Guiguemde, W Armand" sort="Guiguemde, W Armand" uniqKey="Guiguemde W" first="W Armand" last="Guiguemde">W Armand Guiguemde</name>
<name sortKey="Gural, Nil" sort="Gural, Nil" uniqKey="Gural N" first="Nil" last="Gural">Nil Gural</name>
<name sortKey="Guy, R Kiplin" sort="Guy, R Kiplin" uniqKey="Guy R" first="R Kiplin" last="Guy">R Kiplin Guy</name>
<name sortKey="Hanson, Kirsten K" sort="Hanson, Kirsten K" uniqKey="Hanson K" first="Kirsten K" last="Hanson">Kirsten K. Hanson</name>
<name sortKey="Hughes, Tyler B" sort="Hughes, Tyler B" uniqKey="Hughes T" first="Tyler B" last="Hughes">Tyler B. Hughes</name>
<name sortKey="Huston, Christopher" sort="Huston, Christopher" uniqKey="Huston C" first="Christopher" last="Huston">Christopher Huston</name>
<name sortKey="Jadhav, Ajit" sort="Jadhav, Ajit" uniqKey="Jadhav A" first="Ajit" last="Jadhav">Ajit Jadhav</name>
<name sortKey="Jiang, Rays H Y" sort="Jiang, Rays H Y" uniqKey="Jiang R" first="Rays H Y" last="Jiang">Rays H Y. Jiang</name>
<name sortKey="Ketas, Thomas" sort="Ketas, Thomas" uniqKey="Ketas T" first="Thomas" last="Ketas">Thomas Ketas</name>
<name sortKey="Kim, Sunyoung" sort="Kim, Sunyoung" uniqKey="Kim S" first="Sunyoung" last="Kim">Sunyoung Kim</name>
<name sortKey="Kumar, Vidya P" sort="Kumar, Vidya P" uniqKey="Kumar V" first="Vidya P" last="Kumar">Vidya P. Kumar</name>
<name sortKey="Kyle, Dennis E" sort="Kyle, Dennis E" uniqKey="Kyle D" first="Dennis E" last="Kyle">Dennis E. Kyle</name>
<name sortKey="Landfear, Scott" sort="Landfear, Scott" uniqKey="Landfear S" first="Scott" last="Landfear">Scott Landfear</name>
<name sortKey="Le Dang, Na" sort="Le Dang, Na" uniqKey="Le Dang N" first="Na" last="Le Dang">Na Le Dang</name>
<name sortKey="Li, Fengwu" sort="Li, Fengwu" uniqKey="Li F" first="Fengwu" last="Li">Fengwu Li</name>
<name sortKey="Little, David" sort="Little, David" uniqKey="Little D" first="David" last="Little">David Little</name>
<name sortKey="Liu, Liqiong" sort="Liu, Liqiong" uniqKey="Liu L" first="Liqiong" last="Liu">Liqiong Liu</name>
<name sortKey="Llinas, Manuel" sort="Llinas, Manuel" uniqKey="Llinas M" first="Manuel" last="Llinás">Manuel Llinás</name>
<name sortKey="Lubar, Aristea" sort="Lubar, Aristea" uniqKey="Lubar A" first="Aristea" last="Lubar">Aristea Lubar</name>
<name sortKey="March, Sandra" sort="March, Sandra" uniqKey="March S" first="Sandra" last="March">Sandra March</name>
<name sortKey="Meister, Stephan" sort="Meister, Stephan" uniqKey="Meister S" first="Stephan" last="Meister">Stephan Meister</name>
<name sortKey="Mercer, Luke" sort="Mercer, Luke" uniqKey="Mercer L" first="Luke" last="Mercer">Luke Mercer</name>
<name sortKey="Misra, Raj N" sort="Misra, Raj N" uniqKey="Misra R" first="Raj N" last="Misra">Raj N. Misra</name>
<name sortKey="Moore, John P" sort="Moore, John P" uniqKey="Moore J" first="John P" last="Moore">John P. Moore</name>
<name sortKey="Nakazawa Hewitt, Stephen" sort="Nakazawa Hewitt, Stephen" uniqKey="Nakazawa Hewitt S" first="Stephen" last="Nakazawa Hewitt">Stephen Nakazawa Hewitt</name>
<name sortKey="Nare, Bakela" sort="Nare, Bakela" uniqKey="Nare B" first="Bakela" last="Nare">Bakela Nare</name>
<name sortKey="Nathan, Carl" sort="Nathan, Carl" uniqKey="Nathan C" first="Carl" last="Nathan">Carl Nathan</name>
<name sortKey="Ojo, Kayode K" sort="Ojo, Kayode K" uniqKey="Ojo K" first="Kayode K" last="Ojo">Kayode K. Ojo</name>
<name sortKey="Ortiz, Diana" sort="Ortiz, Diana" uniqKey="Ortiz D" first="Diana" last="Ortiz">Diana Ortiz</name>
<name sortKey="Patra, Kailash" sort="Patra, Kailash" uniqKey="Patra K" first="Kailash" last="Patra">Kailash Patra</name>
<name sortKey="Plouffe, David M" sort="Plouffe, David M" uniqKey="Plouffe D" first="David M" last="Plouffe">David M. Plouffe</name>
<name sortKey="Pradhan, Anupam" sort="Pradhan, Anupam" uniqKey="Pradhan A" first="Anupam" last="Pradhan">Anupam Pradhan</name>
<name sortKey="Rice, Christopher A" sort="Rice, Christopher A" uniqKey="Rice C" first="Christopher A" last="Rice">Christopher A. Rice</name>
<name sortKey="Samra, Jasmeet" sort="Samra, Jasmeet" uniqKey="Samra J" first="Jasmeet" last="Samra">Jasmeet Samra</name>
<name sortKey="Schlecht, Ulrich" sort="Schlecht, Ulrich" uniqKey="Schlecht U" first="Ulrich" last="Schlecht">Ulrich Schlecht</name>
<name sortKey="St Onge, Robert" sort="St Onge, Robert" uniqKey="St Onge R" first="Robert" last="St Onge">Robert St Onge</name>
<name sortKey="Sullivan, David J" sort="Sullivan, David J" uniqKey="Sullivan D" first="David J" last="Sullivan">David J. Sullivan</name>
<name sortKey="Sullivan, William" sort="Sullivan, William" uniqKey="Sullivan W" first="William" last="Sullivan">William Sullivan</name>
<name sortKey="Suzuki, Brian M" sort="Suzuki, Brian M" uniqKey="Suzuki B" first="Brian M" last="Suzuki">Brian M. Suzuki</name>
<name sortKey="Suzuki, Yo" sort="Suzuki, Yo" uniqKey="Suzuki Y" first="Yo" last="Suzuki">Yo Suzuki</name>
<name sortKey="Taramelli, Donatella" sort="Taramelli, Donatella" uniqKey="Taramelli D" first="Donatella" last="Taramelli">Donatella Taramelli</name>
<name sortKey="Thomas, David" sort="Thomas, David" uniqKey="Thomas D" first="David" last="Thomas">David Thomas</name>
<name sortKey="Tripathi, Abhai K" sort="Tripathi, Abhai K" uniqKey="Tripathi A" first="Abhai K" last="Tripathi">Abhai K. Tripathi</name>
<name sortKey="Udenze, Kenneth O" sort="Udenze, Kenneth O" uniqKey="Udenze K" first="Kenneth O" last="Udenze">Kenneth O. Udenze</name>
<name sortKey="Vigil, Edgar" sort="Vigil, Edgar" uniqKey="Vigil E" first="Edgar" last="Vigil">Edgar Vigil</name>
<name sortKey="Vinetz, Joseph M" sort="Vinetz, Joseph M" uniqKey="Vinetz J" first="Joseph M" last="Vinetz">Joseph M. Vinetz</name>
<name sortKey="White, Pamela M" sort="White, Pamela M" uniqKey="White P" first="Pamela M" last="White">Pamela M. White</name>
<name sortKey="Winzeler, Elizabeth A" sort="Winzeler, Elizabeth A" uniqKey="Winzeler E" first="Elizabeth A" last="Winzeler">Elizabeth A. Winzeler</name>
<name sortKey="Wojcik, Edward" sort="Wojcik, Edward" uniqKey="Wojcik E" first="Edward" last="Wojcik">Edward Wojcik</name>
<name sortKey="Wree, Melanie" sort="Wree, Melanie" uniqKey="Wree M" first="Melanie" last="Wree">Melanie Wree</name>
<name sortKey="Wu, Wesley" sort="Wu, Wesley" uniqKey="Wu W" first="Wesley" last="Wu">Wesley Wu</name>
</country>
<country name="Suisse"><noRegion><name sortKey="Adelfio, Roberto" sort="Adelfio, Roberto" uniqKey="Adelfio R" first="Roberto" last="Adelfio">Roberto Adelfio</name>
</noRegion>
<name sortKey="Abla, Nada" sort="Abla, Nada" uniqKey="Abla N" first="Nada" last="Abla">Nada Abla</name>
<name sortKey="Baker, Mark" sort="Baker, Mark" uniqKey="Baker M" first="Mark" last="Baker">Mark Baker</name>
<name sortKey="Blasco, Benjamin" sort="Blasco, Benjamin" uniqKey="Blasco B" first="Benjamin" last="Blasco">Benjamin Blasco</name>
<name sortKey="Burrows, Jeremy" sort="Burrows, Jeremy" uniqKey="Burrows J" first="Jeremy" last="Burrows">Jeremy Burrows</name>
<name sortKey="Cowan, Noemi" sort="Cowan, Noemi" uniqKey="Cowan N" first="Noemi" last="Cowan">Noemi Cowan</name>
<name sortKey="Hemphill, Andrew" sort="Hemphill, Andrew" uniqKey="Hemphill A" first="Andrew" last="Hemphill">Andrew Hemphill</name>
<name sortKey="Hooft Van Huijsduijnen, Rob" sort="Hooft Van Huijsduijnen, Rob" uniqKey="Hooft Van Huijsduijnen R" first="Rob" last="Hooft Van Huijsduijnen">Rob Hooft Van Huijsduijnen</name>
<name sortKey="Ingram Sieber, Katrin" sort="Ingram Sieber, Katrin" uniqKey="Ingram Sieber K" first="Katrin" last="Ingram-Sieber">Katrin Ingram-Sieber</name>
<name sortKey="Keiser, Jennifer" sort="Keiser, Jennifer" uniqKey="Keiser J" first="Jennifer" last="Keiser">Jennifer Keiser</name>
<name sortKey="Kicka, Sebastien" sort="Kicka, Sebastien" uniqKey="Kicka S" first="Sebastien" last="Kicka">Sebastien Kicka</name>
<name sortKey="Laleu, Benoit" sort="Laleu, Benoit" uniqKey="Laleu B" first="Benoît" last="Laleu">Benoît Laleu</name>
<name sortKey="Lee, Nathan" sort="Lee, Nathan" uniqKey="Lee N" first="Nathan" last="Lee">Nathan Lee</name>
<name sortKey="Leroy, Didier" sort="Leroy, Didier" uniqKey="Leroy D" first="Didier" last="Leroy">Didier Leroy</name>
<name sortKey="Muller, Joachim" sort="Muller, Joachim" uniqKey="Muller J" first="Joachim" last="Müller">Joachim Müller</name>
<name sortKey="Panic, Gordana" sort="Panic, Gordana" uniqKey="Panic G" first="Gordana" last="Panic">Gordana Panic</name>
<name sortKey="Soldati, Thierry" sort="Soldati, Thierry" uniqKey="Soldati T" first="Thierry" last="Soldati">Thierry Soldati</name>
<name sortKey="Spangenberg, Thomas" sort="Spangenberg, Thomas" uniqKey="Spangenberg T" first="Thomas" last="Spangenberg">Thomas Spangenberg</name>
<name sortKey="Trofimov, Valentin" sort="Trofimov, Valentin" uniqKey="Trofimov V" first="Valentin" last="Trofimov">Valentin Trofimov</name>
<name sortKey="Wells, Timothy" sort="Wells, Timothy" uniqKey="Wells T" first="Timothy" last="Wells">Timothy Wells</name>
<name sortKey="Willis, Paul A" sort="Willis, Paul A" uniqKey="Willis P" first="Paul A" last="Willis">Paul A. Willis</name>
</country>
<country name="Italie"><region name="Latium"><name sortKey="Alano, Pietro" sort="Alano, Pietro" uniqKey="Alano P" first="Pietro" last="Alano">Pietro Alano</name>
</region>
<name sortKey="Camarda, Grazia" sort="Camarda, Grazia" uniqKey="Camarda G" first="Grazia" last="Camarda">Grazia Camarda</name>
<name sortKey="Corbett, Yolanda" sort="Corbett, Yolanda" uniqKey="Corbett Y" first="Yolanda" last="Corbett">Yolanda Corbett</name>
<name sortKey="D Alessandro, Sarah" sort="D Alessandro, Sarah" uniqKey="D Alessandro S" first="Sarah" last="D'Alessandro">Sarah D'Alessandro</name>
<name sortKey="Parapini, Silvia" sort="Parapini, Silvia" uniqKey="Parapini S" first="Silvia" last="Parapini">Silvia Parapini</name>
<name sortKey="Silvestrini, Francesco" sort="Silvestrini, Francesco" uniqKey="Silvestrini F" first="Francesco" last="Silvestrini">Francesco Silvestrini</name>
</country>
<country name="Espagne"><noRegion><name sortKey="Alday, Aintzane" sort="Alday, Aintzane" uniqKey="Alday A" first="Aintzane" last="Alday">Aintzane Alday</name>
</noRegion>
<name sortKey="Alzualde, Ainhoa" sort="Alzualde, Ainhoa" uniqKey="Alzualde A" first="Ainhoa" last="Alzualde">Ainhoa Alzualde</name>
<name sortKey="Brea, Jose" sort="Brea, Jose" uniqKey="Brea J" first="Jose" last="Brea">Jose Brea</name>
<name sortKey="Gamo, Francisco Javier" sort="Gamo, Francisco Javier" uniqKey="Gamo F" first="Francisco Javier" last="Gamo">Francisco Javier Gamo</name>
<name sortKey="Lafuente, Maria Jose" sort="Lafuente, Maria Jose" uniqKey="Lafuente M" first="Maria Jose" last="Lafuente">Maria Jose Lafuente</name>
<name sortKey="Loza, Maria I" sort="Loza, Maria I" uniqKey="Loza M" first="Maria I" last="Loza">Maria I. Loza</name>
<name sortKey="Mestres, Jordi" sort="Mestres, Jordi" uniqKey="Mestres J" first="Jordi" last="Mestres">Jordi Mestres</name>
<name sortKey="Muriana, Arantza" sort="Muriana, Arantza" uniqKey="Muriana A" first="Arantza" last="Muriana">Arantza Muriana</name>
<name sortKey="Prats, Sarah" sort="Prats, Sarah" uniqKey="Prats S" first="Sarah" last="Prats">Sarah Prats</name>
<name sortKey="Quevedo, Celia" sort="Quevedo, Celia" uniqKey="Quevedo C" first="Celia" last="Quevedo">Celia Quevedo</name>
<name sortKey="Spitzmuller, Andreas" sort="Spitzmuller, Andreas" uniqKey="Spitzmuller A" first="Andreas" last="Spitzmüller">Andreas Spitzmüller</name>
</country>
<country name="Irlande (pays)"><noRegion><name sortKey="Alsibaee, Aishah" sort="Alsibaee, Aishah" uniqKey="Alsibaee A" first="Aishah" last="Alsibaee">Aishah Alsibaee</name>
</noRegion>
<name sortKey="Brennan, Marian" sort="Brennan, Marian" uniqKey="Brennan M" first="Marian" last="Brennan">Marian Brennan</name>
<name sortKey="Chubb, Anthony" sort="Chubb, Anthony" uniqKey="Chubb A" first="Anthony" last="Chubb">Anthony Chubb</name>
</country>
<country name="Australie"><noRegion><name sortKey="Andrews, Katherine T" sort="Andrews, Katherine T" uniqKey="Andrews K" first="Katherine T" last="Andrews">Katherine T. Andrews</name>
</noRegion>
<name sortKey="Avery, Vicky M" sort="Avery, Vicky M" uniqKey="Avery V" first="Vicky M" last="Avery">Vicky M. Avery</name>
<name sortKey="Carter, Dee" sort="Carter, Dee" uniqKey="Carter D" first="Dee" last="Carter">Dee Carter</name>
<name sortKey="Duffy, Sandra" sort="Duffy, Sandra" uniqKey="Duffy S" first="Sandra" last="Duffy">Sandra Duffy</name>
<name sortKey="Kirk, Kiaran" sort="Kirk, Kiaran" uniqKey="Kirk K" first="Kiaran" last="Kirk">Kiaran Kirk</name>
<name sortKey="Lehane, Adele M" sort="Lehane, Adele M" uniqKey="Lehane A" first="Adele M" last="Lehane">Adele M. Lehane</name>
<name sortKey="Lucantoni, Leonardo" sort="Lucantoni, Leonardo" uniqKey="Lucantoni L" first="Leonardo" last="Lucantoni">Leonardo Lucantoni</name>
<name sortKey="Lucet, Isabelle" sort="Lucet, Isabelle" uniqKey="Lucet I" first="Isabelle" last="Lucet">Isabelle Lucet</name>
<name sortKey="Mcgowan, Sheena" sort="Mcgowan, Sheena" uniqKey="Mcgowan S" first="Sheena" last="Mcgowan">Sheena Mcgowan</name>
<name sortKey="Nawaratna, Sujeevi" sort="Nawaratna, Sujeevi" uniqKey="Nawaratna S" first="Sujeevi" last="Nawaratna">Sujeevi Nawaratna</name>
<name sortKey="Pham, Ngoc" sort="Pham, Ngoc" uniqKey="Pham N" first="Ngoc" last="Pham">Ngoc Pham</name>
<name sortKey="Poulsen, Sally Ann" sort="Poulsen, Sally Ann" uniqKey="Poulsen S" first="Sally-Ann" last="Poulsen">Sally-Ann Poulsen</name>
<name sortKey="Quinn, Ronald J" sort="Quinn, Ronald J" uniqKey="Quinn R" first="Ronald J" last="Quinn">Ronald J. Quinn</name>
<name sortKey="Tonissen, Kathryn F" sort="Tonissen, Kathryn F" uniqKey="Tonissen K" first="Kathryn F" last="Tonissen">Kathryn F. Tonissen</name>
<name sortKey="Vu, Hoan" sort="Vu, Hoan" uniqKey="Vu H" first="Hoan" last="Vu">Hoan Vu</name>
<name sortKey="Weatherby, Kate" sort="Weatherby, Kate" uniqKey="Weatherby K" first="Kate" last="Weatherby">Kate Weatherby</name>
<name sortKey="Wilks, Andrew F" sort="Wilks, Andrew F" uniqKey="Wilks A" first="Andrew F" last="Wilks">Andrew F. Wilks</name>
</country>
<country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Avery, Simon V" sort="Avery, Simon V" uniqKey="Avery S" first="Simon V" last="Avery">Simon V. Avery</name>
</region>
<name sortKey="Bickle, Quentin" sort="Bickle, Quentin" uniqKey="Bickle Q" first="Quentin" last="Bickle">Quentin Bickle</name>
<name sortKey="Delves, Michael" sort="Delves, Michael" uniqKey="Delves M" first="Michael" last="Delves">Michael Delves</name>
<name sortKey="Gokool, Suzanne" sort="Gokool, Suzanne" uniqKey="Gokool S" first="Suzanne" last="Gokool">Suzanne Gokool</name>
<name sortKey="Horrocks, Paul" sort="Horrocks, Paul" uniqKey="Horrocks P" first="Paul" last="Horrocks">Paul Horrocks</name>
<name sortKey="Mansour, Nuha R" sort="Mansour, Nuha R" uniqKey="Mansour N" first="Nuha R" last="Mansour">Nuha R. Mansour</name>
<name sortKey="Narraidoo, Nathalie" sort="Narraidoo, Nathalie" uniqKey="Narraidoo N" first="Nathalie" last="Narraidoo">Nathalie Narraidoo</name>
<name sortKey="Papadatos, George" sort="Papadatos, George" uniqKey="Papadatos G" first="George" last="Papadatos">George Papadatos</name>
<name sortKey="Ruecker, Andrea" sort="Ruecker, Andrea" uniqKey="Ruecker A" first="Andrea" last="Ruecker">Andrea Ruecker</name>
<name sortKey="Sinden, Robert" sort="Sinden, Robert" uniqKey="Sinden R" first="Robert" last="Sinden">Robert Sinden</name>
<name sortKey="Swamidass, S Joshua" sort="Swamidass, S Joshua" uniqKey="Swamidass S" first="S Joshua" last="Swamidass">S Joshua Swamidass</name>
<name sortKey="Townson, Simon" sort="Townson, Simon" uniqKey="Townson S" first="Simon" last="Townson">Simon Townson</name>
<name sortKey="Ullah, Imran" sort="Ullah, Imran" uniqKey="Ullah I" first="Imran" last="Ullah">Imran Ullah</name>
<name sortKey="Vallieres, Cindy" sort="Vallieres, Cindy" uniqKey="Vallieres C" first="Cindy" last="Vallieres">Cindy Vallieres</name>
</country>
<country name="Corée du Sud"><noRegion><name sortKey="Ayong, Lawrence" sort="Ayong, Lawrence" uniqKey="Ayong L" first="Lawrence" last="Ayong">Lawrence Ayong</name>
</noRegion>
<name sortKey="Hansen, Michael A E" sort="Hansen, Michael A E" uniqKey="Hansen M" first="Michael A E" last="Hansen">Michael A E. Hansen</name>
<name sortKey="Lee, Sukjun" sort="Lee, Sukjun" uniqKey="Lee S" first="Sukjun" last="Lee">Sukjun Lee</name>
<name sortKey="Moon, Seunghyun" sort="Moon, Seunghyun" uniqKey="Moon S" first="Seunghyun" last="Moon">Seunghyun Moon</name>
</country>
<country name="Viêt Nam"><noRegion><name sortKey="Baker, Stephen" sort="Baker, Stephen" uniqKey="Baker S" first="Stephen" last="Baker">Stephen Baker</name>
</noRegion>
<name sortKey="Voong Vinh, Phat" sort="Voong Vinh, Phat" uniqKey="Voong Vinh P" first="Phat" last="Voong Vinh">Phat Voong Vinh</name>
</country>
<country name="France"><noRegion><name sortKey="Bounaadja, Lotfi" sort="Bounaadja, Lotfi" uniqKey="Bounaadja L" first="Lotfi" last="Bounaadja">Lotfi Bounaadja</name>
</noRegion>
<name sortKey="Florent, Isabelle" sort="Florent, Isabelle" uniqKey="Florent I" first="Isabelle" last="Florent">Isabelle Florent</name>
<name sortKey="Schmitt, Marjorie" sort="Schmitt, Marjorie" uniqKey="Schmitt M" first="Marjorie" last="Schmitt">Marjorie Schmitt</name>
</country>
<country name="Cameroun"><noRegion><name sortKey="Boyom, Fabrice F" sort="Boyom, Fabrice F" uniqKey="Boyom F" first="Fabrice F" last="Boyom">Fabrice F. Boyom</name>
</noRegion>
<name sortKey="Fokou, Patrick V T" sort="Fokou, Patrick V T" uniqKey="Fokou P" first="Patrick V T" last="Fokou">Patrick V T. Fokou</name>
<name sortKey="Mfopa, Alvine N" sort="Mfopa, Alvine N" uniqKey="Mfopa A" first="Alvine N" last="Mfopa">Alvine N. Mfopa</name>
<name sortKey="Tchokouaha, Lauve R Y" sort="Tchokouaha, Lauve R Y" uniqKey="Tchokouaha L" first="Lauve R Y" last="Tchokouaha">Lauve R Y. Tchokouaha</name>
<name sortKey="Zollo, Paul H A" sort="Zollo, Paul H A" uniqKey="Zollo P" first="Paul H A" last="Zollo">Paul H A. Zollo</name>
</country>
<country name="Thaïlande"><noRegion><name sortKey="Chindaudomsate, Worathad" sort="Chindaudomsate, Worathad" uniqKey="Chindaudomsate W" first="Worathad" last="Chindaudomsate">Worathad Chindaudomsate</name>
</noRegion>
<name sortKey="Jensen, Laran T" sort="Jensen, Laran T" uniqKey="Jensen L" first="Laran T" last="Jensen">Laran T. Jensen</name>
</country>
<country name="Japon"><noRegion><name sortKey="Abd El Salam El Sayed, Shimaa" sort="Abd El Salam El Sayed, Shimaa" uniqKey="Abd El Salam El Sayed S" first="Shimaa" last="Abd El-Salam El-Sayed">Shimaa Abd El-Salam El-Sayed</name>
</noRegion>
<name sortKey="Abdo Rizk, Mohamed" sort="Abdo Rizk, Mohamed" uniqKey="Abdo Rizk M" first="Mohamed" last="Abdo Rizk">Mohamed Abdo Rizk</name>
<name sortKey="Horii, Takaaki" sort="Horii, Takaaki" uniqKey="Horii T" first="Takaaki" last="Horii">Takaaki Horii</name>
<name sortKey="Igarashi, Ikuo" sort="Igarashi, Ikuo" uniqKey="Igarashi I" first="Ikuo" last="Igarashi">Ikuo Igarashi</name>
<name sortKey="Watanabe, Nao Aki" sort="Watanabe, Nao Aki" uniqKey="Watanabe N" first="Nao-Aki" last="Watanabe">Nao-Aki Watanabe</name>
<name sortKey="Yokoyama, Naoaki" sort="Yokoyama, Naoaki" uniqKey="Yokoyama N" first="Naoaki" last="Yokoyama">Naoaki Yokoyama</name>
</country>
<country name="Portugal"><noRegion><name sortKey="Itoe, Maurice A" sort="Itoe, Maurice A" uniqKey="Itoe M" first="Maurice A" last="Itoe">Maurice A. Itoe</name>
</noRegion>
<name sortKey="Medina Vera, Iset" sort="Medina Vera, Iset" uniqKey="Medina Vera I" first="Iset" last="Medina Vera">Iset Medina Vera</name>
</country>
<country name="Allemagne"><noRegion><name sortKey="Kaiser, Annette" sort="Kaiser, Annette" uniqKey="Kaiser A" first="Annette" last="Kaiser">Annette Kaiser</name>
</noRegion>
</country>
<country name="Belgique"><region name="Province d'Anvers"><name sortKey="Maes, Louis" sort="Maes, Louis" uniqKey="Maes L" first="Louis" last="Maes">Louis Maes</name>
</region>
</country>
<country name="Afrique du Sud"><noRegion><name sortKey="Mancama, Dalu" sort="Mancama, Dalu" uniqKey="Mancama D" first="Dalu" last="Mancama">Dalu Mancama</name>
</noRegion>
<name sortKey="Smith, Dennis A" sort="Smith, Dennis A" uniqKey="Smith D" first="Dennis A" last="Smith">Dennis A. Smith</name>
<name sortKey="Theron, Anjo" sort="Theron, Anjo" uniqKey="Theron A" first="Anjo" last="Theron">Anjo Theron</name>
</country>
<country name="Brésil"><region name="Minas Gerais"><name sortKey="Morais Rodrigues Da Costa, Francielly" sort="Morais Rodrigues Da Costa, Francielly" uniqKey="Morais Rodrigues Da Costa F" first="Francielly" last="Morais Rodrigues Da Costa">Francielly Morais Rodrigues Da Costa</name>
</region>
<name sortKey="Salgado Ferreira, Rafaela" sort="Salgado Ferreira, Rafaela" uniqKey="Salgado Ferreira R" first="Rafaela" last="Salgado Ferreira">Rafaela Salgado Ferreira</name>
<name sortKey="Silva Villela, Filipe" sort="Silva Villela, Filipe" uniqKey="Silva Villela F" first="Filipe" last="Silva Villela">Filipe Silva Villela</name>
<name sortKey="Suresh, Sundari" sort="Suresh, Sundari" uniqKey="Suresh S" first="Sundari" last="Suresh">Sundari Suresh</name>
</country>
</tree>
</affiliations>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Belgique/explor/OpenAccessBelV2/Data/PubMed/Checkpoint
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000006 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PubMed/Checkpoint/biblio.hfd -nk 000006 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Belgique |area= OpenAccessBelV2 |flux= PubMed |étape= Checkpoint |type= RBID |clé= pubmed:27467575 |texte= Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond. }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Checkpoint/RBID.i -Sk "pubmed:27467575" \ | HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Checkpoint/biblio.hfd \ | NlmPubMed2Wicri -a OpenAccessBelV2
![]() | This area was generated with Dilib version V0.6.25. | ![]() |