Implementation and Operational Research: Computer-Assisted Intervention for Safer Sex in HIV-Positive Men Having Sex With Men: Findings of a European Randomized Multi-Center Trial
Identifieur interne : 000095 ( Pmc/Curation ); précédent : 000094; suivant : 000096Implementation and Operational Research: Computer-Assisted Intervention for Safer Sex in HIV-Positive Men Having Sex With Men: Findings of a European Randomized Multi-Center Trial
Auteurs : Christiana Nöstlinger ; Tom Platteau [Belgique] ; Johannes Bogner [Allemagne] ; Jozefien Buyze [Belgique] ; Joanna Dec-Pietrowska [Pologne] ; Sonia Dias [Portugal] ; John Newbury-Helps [Royaume-Uni] ; Agnes Kocsis [Royaume-Uni] ; Matthias Mueller [Allemagne] ; Daniela Rojas [France] ; Danica Stanekova ; Jacques Van Lankveld [Pays-Bas] ; Robert Colebunders [Belgique]Source :
- Journal of Acquired Immune Deficiency Syndromes (1999) [ 1525-4135 ] ; 2016.
Abstract
Supplemental Digital Content is Available in the Text.
Url:
DOI: 10.1097/QAI.0000000000000882
PubMed: 26866955
PubMed Central: 4770369
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Danica Stanekova<affiliation><nlm:aff id="aff9">National Reference Centre for HIV/AIDS Prevention, Slovak Medical University, Bratislava, Slovak Republic;</nlm:aff>
<wicri:noCountry code="subfield">Slovak Republic</wicri:noCountry>
</affiliation>
Le document en format XML
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</TEI>
<pmc article-type="research-article"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">J Acquir Immune Defic Syndr</journal-id>
<journal-id journal-id-type="iso-abbrev">J. Acquir. Immune Defic. Syndr</journal-id>
<journal-id journal-id-type="publisher-id">qai</journal-id>
<journal-title-group><journal-title>Journal of Acquired Immune Deficiency Syndromes (1999)</journal-title>
</journal-title-group>
<issn pub-type="ppub">1525-4135</issn>
<issn pub-type="epub">1944-7884</issn>
<publisher><publisher-name>JAIDS Journal of Acquired Immune Deficiency Syndromes</publisher-name>
</publisher>
</journal-meta>
<article-meta><article-id pub-id-type="pmid">26866955</article-id>
<article-id pub-id-type="pmc">4770369</article-id>
<article-id pub-id-type="publisher-id">QAIV15689</article-id>
<article-id pub-id-type="doi">10.1097/QAI.0000000000000882</article-id>
<article-id pub-id-type="art-access-id">00016</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Epidemiology and Prevention</subject>
</subj-group>
</article-categories>
<title-group><article-title>Implementation and Operational Research: Computer-Assisted Intervention for Safer Sex in HIV-Positive Men Having Sex With Men: Findings of a European Randomized Multi-Center Trial</article-title>
</title-group>
<contrib-group><contrib contrib-type="author" corresp="yes"><name><surname>Nöstlinger</surname>
<given-names>Christiana</given-names>
</name>
<degrees>PhD</degrees>
<xref ref-type="aff" rid="aff1">*</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Platteau</surname>
<given-names>Tom</given-names>
</name>
<degrees>MSc</degrees>
<xref ref-type="aff" rid="aff2">†</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Bogner</surname>
<given-names>Johannes</given-names>
</name>
<degrees>PhD, MD</degrees>
<xref ref-type="aff" rid="aff3">‡</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Buyze</surname>
<given-names>Jozefien</given-names>
</name>
<degrees>PhD</degrees>
<xref ref-type="aff" rid="aff2">†</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Dec-Pietrowska</surname>
<given-names>Joanna</given-names>
</name>
<degrees>PhD</degrees>
<xref ref-type="aff" rid="aff4">§</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Dias</surname>
<given-names>Sonia</given-names>
</name>
<degrees>PhD</degrees>
<xref ref-type="aff" rid="aff5">‖</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Newbury-Helps</surname>
<given-names>John</given-names>
</name>
<degrees>PhD</degrees>
<xref ref-type="aff" rid="aff6">¶</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Kocsis</surname>
<given-names>Agnes</given-names>
</name>
<degrees>PhD</degrees>
<xref ref-type="aff" rid="aff6">¶</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Mueller</surname>
<given-names>Matthias</given-names>
</name>
<degrees>MD</degrees>
<xref ref-type="aff" rid="aff3">‡</xref>
<xref ref-type="aff" rid="aff7">#</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Rojas</surname>
<given-names>Daniela</given-names>
</name>
<degrees>PhD</degrees>
<xref ref-type="aff" rid="aff8">**</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Stanekova</surname>
<given-names>Danica</given-names>
</name>
<degrees>MD</degrees>
<xref ref-type="aff" rid="aff9">††</xref>
</contrib>
<contrib contrib-type="author"><name><surname>van Lankveld</surname>
<given-names>Jacques</given-names>
</name>
<degrees>PhD</degrees>
<xref ref-type="aff" rid="aff10">‡‡</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Colebunders</surname>
<given-names>Robert</given-names>
</name>
<degrees>MD, PhD</degrees>
<xref ref-type="aff" rid="aff2">†</xref>
<xref ref-type="aff" rid="aff11">§§</xref>
</contrib>
<contrib contrib-type="author"><collab>the Eurosupport Study Group</collab>
</contrib>
<aff id="aff1">Departments of<label>*</label>
Public Health;</aff>
<aff id="aff2"><label>†</label>
Clinical Sciences, Institute of Tropical Medicine, ITM's HIV AIDS Center (IHAC), Antwerp, Belgium;</aff>
<aff id="aff3"><label>‡</label>
Department of Infectious Diseases, Ludwig-Maximilian University, University Hospital Munich, Munich, Germany;</aff>
<aff id="aff4"><label>§</label>
Faculty of Education, Sociology, and Health Services, University of Zielona Gora, Zielona Gora, Poland;</aff>
<aff id="aff5"><label>‖</label>
Institute of Tropical Medicine and Hygiene, Lisbon, Portugal;</aff>
<aff id="aff6"><label>¶</label>
Central North West London NHS Trust, London, United Kingdom;</aff>
<aff id="aff7"><label>#</label>
Department of Medicine, Center for Infectious Diseases and Travel Medicine and IFB Center for Chronic Immunodeficiency, University Medical Center Freiburg, Freiburg, Germany;</aff>
<aff id="aff8"><label>**</label>
AIDES, Mission Innovation Recherche Expérimentation (MIRE), Paris, France;</aff>
<aff id="aff9"><label>††</label>
National Reference Centre for HIV/AIDS Prevention, Slovak Medical University, Bratislava, Slovak Republic;</aff>
<aff id="aff10"><label>‡‡</label>
Faculty of Psychology and Educational Sciences, Open University, Heerlen, the Netherlands; and</aff>
<aff id="aff11"><label>§§</label>
Department of Epidemiology and Social Medicine, University of Antwerp, Antwerp, Belgium.</aff>
</contrib-group>
<author-notes><corresp>Correspondence to: Christiana Nöstlinger, PhD, Department of Public Health, Institute of Tropical Medicine, Nationalestraat 155, B-2000 Antwerp, Belgium (e-mail: <email>cnoestlinger@itg.be</email>
).</corresp>
</author-notes>
<pub-date pub-type="ppub"><day>1</day>
<month>3</month>
<year>2016</year>
</pub-date>
<pub-date pub-type="epub"><day>10</day>
<month>2</month>
<year>2016</year>
</pub-date>
<volume>71</volume>
<issue>3</issue>
<fpage>e63</fpage>
<lpage>e72</lpage>
<history><date date-type="received"><day>14</day>
<month>5</month>
<year>2015</year>
</date>
<date date-type="accepted"><day>14</day>
<month>10</month>
<year>2015</year>
</date>
</history>
<permissions><copyright-statement>Copyright © 2015 Wolters Kluwer Health, Inc. All rights reserved.</copyright-statement>
<copyright-year>2015</copyright-year>
</permissions>
<self-uri xlink:type="simple" xlink:href="qai-71-e63.pdf"></self-uri>
<abstract abstract-type="toc"><p>Supplemental Digital Content is Available in the Text.</p>
</abstract>
<abstract><sec><title>Objective:</title>
<p>Men who have sex with men (MSM) are the key population most affected by HIV in Europe. We performed the first European multicenter, simple-randomized parallel-group study to test the effectiveness of a theory-guided computer-assisted intervention to improve safer sex among HIV-positive men who have sex with men.</p>
</sec>
<sec><title>Methods:</title>
<p>Between February, 2011 and February, 2013, 112 participants were enrolled in 8 different European HIV-care settings. Intervention participants received 3 individual counseling sessions facilitated by trained service providers using computer-assisted tools. The control-group received sexual health advice delivered as part of regular HIV care. Outcome behavior (self-reported condom use at last intercourse; combined HIV transmission risk score), its influencing factors, and mediating variables were assessed at baseline, and at 3 and 6 months follow-up. Mixed effects models were used to compare primary outcomes (condom use at last intercourse, HIV transmission risk score), and mediation analysis to explore intervention effects.</p>
</sec>
<sec><title>Results:</title>
<p>Condom use at last intercourse increased more among intervention than control participants at 3 months follow-up (odds ratio of 3.83; <italic>P</italic>
= 0.03), but not significantly at 6 months follow-up. Intervention participants reported a lower transmission risk at 3 months follow-up than controls (odds ratio compared with baseline of 11.53 and 1.28, respectively; <italic>P</italic>
= 0.008), but this effect became nonsignificant at 6 months. Intervention effects were mediated by the proximal variables, self-efficacy to negotiate condom use and condom attitudes.</p>
</sec>
<sec><title>Conclusions:</title>
<p>This intervention showed short-term effectiveness. The intervention should be replicated in other settings, eventually investigating if booster-counseling sessions would yield a longer lasting effect.</p>
</sec>
</abstract>
<kwd-group><title>Key Words:</title>
<kwd>HIV</kwd>
<kwd>safer sex</kwd>
<kwd>theory-based intervention</kwd>
<kwd>condom use</kwd>
<kwd>men having sex with men</kwd>
<kwd>behavioral counseling</kwd>
</kwd-group>
<custom-meta-group><custom-meta><meta-name>SDC</meta-name>
<meta-value>T</meta-value>
</custom-meta>
<custom-meta><meta-name>STATUS</meta-name>
<meta-value>ONLINE-ONLY</meta-value>
</custom-meta>
</custom-meta-group>
</article-meta>
</front>
</pmc>
</record>
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