Contemporary Trends of Reported Sepsis Among Maternal Decedents in Texas: A Population-Based Study
Identifieur interne : 000348 ( Ncbi/Merge ); précédent : 000347; suivant : 000349Contemporary Trends of Reported Sepsis Among Maternal Decedents in Texas: A Population-Based Study
Auteurs : Lavi Oud [États-Unis]Source :
- Infectious Diseases and Therapy [ 2193-8229 ] ; 2015.
Abstract
Recent studies indicate that death certificate-based single-cause-of-death diagnoses can substantially underestimate the contribution of sepsis to mortality in the general population and among maternal decedents. There are no population-based data in the United States on the patterns of the contribution of sepsis to pregnancy-associated deaths.
We studied the Texas Inpatient Public Use Data File to identify pregnancy-associated hospitalizations with reported hospital death during 2001–2010. We then examined the annual reporting of sepsis, and that of other reported most common causes of maternal death, including hemorrhage, embolism, preeclampsia/eclampsia, cardiovascular conditions, cardiomyopathy, cerebrovascular accidents, and anesthesia complications. The annual rate of sepsis among decedents, its trend over time, and changes of its annual rank among other examined potential causes of maternal death were assessed.
There were 557 pregnancy-associated hospital deaths during study period. Sepsis was reported in 131 (23.5%) decedents. Sepsis has been increasingly reported among decedents, rising by 9.1%/year (
Sepsis has become the most commonly reported potential cause of death among maternal decedents in the present cohort, noted in over 1 in 4 fatal hospitalizations by the end of the last decade. Although causality cannot be inferred from administrative data, given its known contribution to maternal death, it is likely that sepsis plays an increasing role in fatal maternal hospital outcomes. The prevalent co-reporting of multiple potential causes of maternal death in the present cohort underscores the complexity of determining the sources of evolving rise of maternal mortality.
The online version of this article (doi:10.1007/s40121-015-0086-6) contains supplementary material, which is available to authorized users.
Url:
DOI: 10.1007/s40121-015-0086-6
PubMed: 26334239
PubMed Central: 4575290
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Contemporary Trends of Reported Sepsis Among Maternal Decedents in Texas: A Population-Based Study</title><author><name sortKey="Oud, Lavi" sort="Oud, Lavi" uniqKey="Oud L" first="Lavi" last="Oud">Lavi Oud</name><affiliation wicri:level="2"><nlm:aff id="Aff1">Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Texas Tech University Health Sciences Center at the Permian Basin, Odessa, TX USA</nlm:aff><country>États-Unis</country><placeName><region type="state">Texas</region></placeName><wicri:cityArea>Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Texas Tech University Health Sciences Center at the Permian Basin, Odessa</wicri:cityArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">26334239</idno><idno type="pmc">4575290</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4575290</idno><idno type="RBID">PMC:4575290</idno><idno type="doi">10.1007/s40121-015-0086-6</idno><date when="2015">2015</date><idno type="wicri:Area/Pmc/Corpus">000149</idno><idno type="wicri:Area/Pmc/Curation">000149</idno><idno type="wicri:Area/Pmc/Checkpoint">000150</idno><idno type="wicri:Area/Ncbi/Merge">000348</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Contemporary Trends of Reported Sepsis Among Maternal Decedents in Texas: A Population-Based Study</title><author><name sortKey="Oud, Lavi" sort="Oud, Lavi" uniqKey="Oud L" first="Lavi" last="Oud">Lavi Oud</name><affiliation wicri:level="2"><nlm:aff id="Aff1">Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Texas Tech University Health Sciences Center at the Permian Basin, Odessa, TX USA</nlm:aff><country>États-Unis</country><placeName><region type="state">Texas</region></placeName><wicri:cityArea>Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Texas Tech University Health Sciences Center at the Permian Basin, Odessa</wicri:cityArea></affiliation></author></analytic><series><title level="j">Infectious Diseases and Therapy</title><idno type="ISSN">2193-8229</idno><idno type="eISSN">2193-6382</idno><imprint><date when="2015">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec><title>Introduction</title><p>Recent studies indicate that death certificate-based single-cause-of-death diagnoses can substantially underestimate the contribution of sepsis to mortality in the general population and among maternal decedents. There are no population-based data in the United States on the patterns of the contribution of sepsis to pregnancy-associated deaths.</p></sec><sec><title>Methods</title><p>We studied the Texas Inpatient Public Use Data File to identify pregnancy-associated hospitalizations with reported hospital death during 2001–2010. We then examined the annual reporting of sepsis, and that of other reported most common causes of maternal death, including hemorrhage, embolism, preeclampsia/eclampsia, cardiovascular conditions, cardiomyopathy, cerebrovascular accidents, and anesthesia complications. The annual rate of sepsis among decedents, its trend over time, and changes of its annual rank among other examined potential causes of maternal death were assessed.</p></sec><sec><title>Results</title><p>There were 557 pregnancy-associated hospital deaths during study period. Sepsis was reported in 131 (23.5%) decedents. Sepsis has been increasingly reported among decedents, rising by 9.1%/year (<italic>P</italic> = 0.0025). The rank of sepsis, as compared to the other examined potential causes of maternal death rose from the 5th in 2001 to 1st since 2008. At the end of the last decade, sepsis has been reported in 28.1% of pregnancy-associated deaths. More than one potential cause of maternal death was reported in 39% of decedents.</p></sec><sec><title>Conclusion</title><p>Sepsis has become the most commonly reported potential cause of death among maternal decedents in the present cohort, noted in over 1 in 4 fatal hospitalizations by the end of the last decade. Although causality cannot be inferred from administrative data, given its known contribution to maternal death, it is likely that sepsis plays an increasing role in fatal maternal hospital outcomes. The prevalent co-reporting of multiple potential causes of maternal death in the present cohort underscores the complexity of determining the sources of evolving rise of maternal mortality.</p></sec><sec><title>Electronic supplementary material</title><p>The online version of this article (doi:10.1007/s40121-015-0086-6) contains supplementary material, which is available to authorized users.</p></sec></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Cantwell, R" uniqKey="Cantwell R">R Cantwell</name></author><author><name sortKey="Clutton Brock, T" uniqKey="Clutton Brock T">T Clutton-Brock</name></author><author><name sortKey="Cooper, G" uniqKey="Cooper G">G Cooper</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Creanga, Aa" uniqKey="Creanga A">AA Creanga</name></author><author><name sortKey="Berg, Cj" uniqKey="Berg C">CJ Berg</name></author><author><name sortKey="Syverson, 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uniqKey="Habli M">M Habli</name></author><author><name sortKey="Sibai, Bm" uniqKey="Sibai B">BM Sibai</name></author></analytic></biblStruct></listBibl></div1></back></TEI><pmc article-type="research-article"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Infect Dis Ther</journal-id><journal-id journal-id-type="iso-abbrev">Infect Dis Ther</journal-id><journal-title-group><journal-title>Infectious Diseases and Therapy</journal-title></journal-title-group><issn pub-type="ppub">2193-8229</issn><issn pub-type="epub">2193-6382</issn><publisher><publisher-name>Springer Healthcare</publisher-name><publisher-loc>Cheshire</publisher-loc></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">26334239</article-id><article-id pub-id-type="pmc">4575290</article-id><article-id pub-id-type="publisher-id">86</article-id><article-id pub-id-type="doi">10.1007/s40121-015-0086-6</article-id><article-categories><subj-group subj-group-type="heading"><subject>Original Research</subject></subj-group></article-categories><title-group><article-title>Contemporary Trends of Reported Sepsis Among Maternal Decedents in Texas: A Population-Based Study</article-title></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name><surname>Oud</surname><given-names>Lavi</given-names></name><address><email>lavi.oud@ttuhsc.edu</email></address><xref ref-type="aff" rid="Aff1"></xref></contrib><aff id="Aff1">Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Texas Tech University Health Sciences Center at the Permian Basin, Odessa, TX USA</aff></contrib-group><pub-date pub-type="epub"><day>3</day><month>9</month><year>2015</year></pub-date><pub-date pub-type="pmc-release"><day>3</day><month>9</month><year>2015</year></pub-date><pub-date pub-type="ppub"><month>9</month><year>2015</year></pub-date><volume>4</volume><issue>3</issue><fpage>321</fpage><lpage>335</lpage><history><date date-type="received"><day>23</day><month>7</month><year>2015</year></date></history><permissions><copyright-statement>© The Author(s) 2015</copyright-statement></permissions><abstract id="Abs1"><sec><title>Introduction</title><p>Recent studies indicate that death certificate-based single-cause-of-death diagnoses can substantially underestimate the contribution of sepsis to mortality in the general population and among maternal decedents. There are no population-based data in the United States on the patterns of the contribution of sepsis to pregnancy-associated deaths.</p></sec><sec><title>Methods</title><p>We studied the Texas Inpatient Public Use Data File to identify pregnancy-associated hospitalizations with reported hospital death during 2001–2010. We then examined the annual reporting of sepsis, and that of other reported most common causes of maternal death, including hemorrhage, embolism, preeclampsia/eclampsia, cardiovascular conditions, cardiomyopathy, cerebrovascular accidents, and anesthesia complications. The annual rate of sepsis among decedents, its trend over time, and changes of its annual rank among other examined potential causes of maternal death were assessed.</p></sec><sec><title>Results</title><p>There were 557 pregnancy-associated hospital deaths during study period. Sepsis was reported in 131 (23.5%) decedents. Sepsis has been increasingly reported among decedents, rising by 9.1%/year (<italic>P</italic> = 0.0025). The rank of sepsis, as compared to the other examined potential causes of maternal death rose from the 5th in 2001 to 1st since 2008. At the end of the last decade, sepsis has been reported in 28.1% of pregnancy-associated deaths. More than one potential cause of maternal death was reported in 39% of decedents.</p></sec><sec><title>Conclusion</title><p>Sepsis has become the most commonly reported potential cause of death among maternal decedents in the present cohort, noted in over 1 in 4 fatal hospitalizations by the end of the last decade. Although causality cannot be inferred from administrative data, given its known contribution to maternal death, it is likely that sepsis plays an increasing role in fatal maternal hospital outcomes. The prevalent co-reporting of multiple potential causes of maternal death in the present cohort underscores the complexity of determining the sources of evolving rise of maternal mortality.</p></sec><sec><title>Electronic supplementary material</title><p>The online version of this article (doi:10.1007/s40121-015-0086-6) contains supplementary material, which is available to authorized users.</p></sec></abstract><kwd-group xml:lang="en"><title>Keywords</title><kwd>Mortality</kwd><kwd>Pregnancy</kwd><kwd>Sepsis</kwd></kwd-group><custom-meta-group><custom-meta><meta-name>issue-copyright-statement</meta-name><meta-value>© Springer Healthcare 2015</meta-value></custom-meta></custom-meta-group></article-meta></front></pmc><affiliations><list><country><li>États-Unis</li></country><region><li>Texas</li></region></list><tree><country name="États-Unis"><region name="Texas"><name sortKey="Oud, Lavi" sort="Oud, Lavi" uniqKey="Oud L" first="Lavi" last="Oud">Lavi Oud</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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