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Osteoporosis in the European Union: a compendium of country-specific reports

Identifieur interne : 000205 ( Ncbi/Merge ); précédent : 000204; suivant : 000206

Osteoporosis in the European Union: a compendium of country-specific reports

Auteurs : A. Svedbom [Suède] ; E. Hernlund [Suède] ; M. Iverg Rd [Suède] ; J. Compston [Royaume-Uni] ; C. Cooper [Royaume-Uni] ; J. Stenmark [Suisse] ; E. V. Mccloskey [Royaume-Uni] ; B. Jönsson [Suède] ; J. A. Kanis [Royaume-Uni]

Source :

RBID : PMC:3880492

Abstract

Summary

This report describes epidemiology, burden, and treatment of osteoporosis in each of the 27 countries of the European Union (EU27).

Introduction

In 2010, 22 million women and 5.5 million men were estimated to have osteoporosis in the EU; and 3.5 million new fragility fractures were sustained, comprising 620,000 hip fractures, 520,000 vertebral fractures, 560,000 forearm fractures and 1,800,000 other fractures. The economic burden of incident and prior fragility fractures was estimated at € 37 billion. Previous and incident fractures also accounted for 1,180,000 quality-adjusted life years lost during 2010. The costs are expected to increase by 25 % in 2025. The majority of individuals who have sustained an osteoporosis-related fracture or who are at high risk of fracture are untreated and the number of patients on treatment is declining. The aim of this report was to characterize the burden of osteoporosis in each of the EU27 countries in 2010 and beyond.

Methods

The data on fracture incidence and costs of fractures in the EU27 were taken from a concurrent publication in this journal (Osteoporosis in the European Union: Medical Management, Epidemiology and Economic Burden) and country specific information extracted.

Results

The clinical and economic burden of osteoporotic fractures in 2010 is given for each of the 27 countries of the EU. The costs are expected to increase on average by 25 % in 2025. The majority of individuals who have sustained an osteoporosis-related fracture or who are at high risk of fracture are untreated and the number of patients on treatment is declining.

Conclusions

In spite of the high cost of osteoporosis, a substantial treatment gap and projected increase of the economic burden driven by aging populations, the use of pharmacological prevention of osteoporosis has decreased in recent years, suggesting that a change in healthcare policy concerning the disease is warranted.


Url:
DOI: 10.1007/s11657-013-0137-0
PubMed: 24113838
PubMed Central: 3880492

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Le document en format XML

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<sec>
<title>Summary</title>
<p>This report describes epidemiology, burden, and treatment of osteoporosis in each of the 27 countries of the European Union (EU27).</p>
</sec>
<sec>
<title>Introduction</title>
<p>In 2010, 22 million women and 5.5 million men were estimated to have osteoporosis in the EU; and 3.5 million new fragility fractures were sustained, comprising 620,000 hip fractures, 520,000 vertebral fractures, 560,000 forearm fractures and 1,800,000 other fractures. The economic burden of incident and prior fragility fractures was estimated at € 37 billion. Previous and incident fractures also accounted for 1,180,000 quality-adjusted life years lost during 2010. The costs are expected to increase by 25 % in 2025. The majority of individuals who have sustained an osteoporosis-related fracture or who are at high risk of fracture are untreated and the number of patients on treatment is declining. The aim of this report was to characterize the burden of osteoporosis in each of the EU27 countries in 2010 and beyond.</p>
</sec>
<sec>
<title>Methods</title>
<p>The data on fracture incidence and costs of fractures in the EU27 were taken from a concurrent publication in this journal (Osteoporosis in the European Union: Medical Management, Epidemiology and Economic Burden) and country specific information extracted.</p>
</sec>
<sec>
<title>Results</title>
<p>The clinical and economic burden of osteoporotic fractures in 2010 is given for each of the 27 countries of the EU. The costs are expected to increase on average by 25 % in 2025. The majority of individuals who have sustained an osteoporosis-related fracture or who are at high risk of fracture are untreated and the number of patients on treatment is declining.</p>
</sec>
<sec>
<title>Conclusions</title>
<p>In spite of the high cost of osteoporosis, a substantial treatment gap and projected increase of the economic burden driven by aging populations, the use of pharmacological prevention of osteoporosis has decreased in recent years, suggesting that a change in healthcare policy concerning the disease is warranted.</p>
</sec>
</div>
</front>
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<journal-id journal-id-type="nlm-ta">Arch Osteoporos</journal-id>
<journal-id journal-id-type="iso-abbrev">Arch Osteoporos</journal-id>
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<journal-title>Archives of Osteoporosis</journal-title>
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<issn pub-type="ppub">1862-3522</issn>
<issn pub-type="epub">1862-3514</issn>
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<publisher-name>Springer London</publisher-name>
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<article-id pub-id-type="publisher-id">137</article-id>
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<article-title>Osteoporosis in the European Union: a compendium of country-specific reports</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname>Svedbom</surname>
<given-names>A.</given-names>
</name>
<xref ref-type="aff" rid="Aff1"></xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Hernlund</surname>
<given-names>E.</given-names>
</name>
<xref ref-type="aff" rid="Aff1"></xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Ivergård</surname>
<given-names>M.</given-names>
</name>
<xref ref-type="aff" rid="Aff1"></xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Compston</surname>
<given-names>J.</given-names>
</name>
<xref ref-type="aff" rid="Aff2"></xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Cooper</surname>
<given-names>C.</given-names>
</name>
<xref ref-type="aff" rid="Aff3"></xref>
<xref ref-type="aff" rid="Aff4"></xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Stenmark</surname>
<given-names>J.</given-names>
</name>
<xref ref-type="aff" rid="Aff5"></xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>McCloskey</surname>
<given-names>E. V.</given-names>
</name>
<xref ref-type="aff" rid="Aff6"></xref>
<xref ref-type="aff" rid="Aff7"></xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Jönsson</surname>
<given-names>B.</given-names>
</name>
<xref ref-type="aff" rid="Aff8"></xref>
</contrib>
<contrib contrib-type="author" corresp="yes">
<name>
<surname>Kanis</surname>
<given-names>J. A.</given-names>
</name>
<address>
<phone>+44-114-2851109</phone>
<fax>+44-114-2851813</fax>
<email>w.j.pontefract@sheffield.ac.uk</email>
</address>
<xref ref-type="aff" rid="Aff7"></xref>
<xref ref-type="aff" rid="Aff9"></xref>
</contrib>
<contrib contrib-type="author">
<collab>the EU review panel of the IOF</collab>
</contrib>
<aff id="Aff1">
<label></label>
OptumInsight, Stockholm, Sweden</aff>
<aff id="Aff2">
<label></label>
Department of Medicine, Addenbrooke’s Hospital, Cambridge University, Cambridge, UK</aff>
<aff id="Aff3">
<label></label>
MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton, UK</aff>
<aff id="Aff4">
<label></label>
NIHR Musculoskeletal Biomedical Research Unit, Institute of Musculoskeletal Sciences, University of Oxford, Oxford, UK</aff>
<aff id="Aff5">
<label></label>
International Osteoporosis Foundation, Nyon, Switzerland</aff>
<aff id="Aff6">
<label></label>
Academic Unit of Bone Metabolism, Northern General Hospital, Sheffield, UK</aff>
<aff id="Aff7">
<label></label>
WHO Collaborating Centre for Metabolic Bone Diseases, University of Sheffield, Sheffield, UK</aff>
<aff id="Aff8">
<label></label>
Stockholm School of Economics, Stockholm, Sweden</aff>
<aff id="Aff9">
<label></label>
WHO Collaborating Centre for Metabolic Bone Diseases, University of Sheffield Medical School, Beech Hill Road, Sheffield, S10 2RX UK</aff>
</contrib-group>
<pub-date pub-type="epub">
<day>11</day>
<month>10</month>
<year>2013</year>
</pub-date>
<pub-date pub-type="pmc-release">
<day>11</day>
<month>10</month>
<year>2013</year>
</pub-date>
<pub-date pub-type="ppub">
<year>2013</year>
</pub-date>
<volume>8</volume>
<issue>1-2</issue>
<elocation-id>137</elocation-id>
<history>
<date date-type="received">
<day>29</day>
<month>11</month>
<year>2012</year>
</date>
<date date-type="accepted">
<day>15</day>
<month>3</month>
<year>2013</year>
</date>
</history>
<permissions>
<copyright-statement>© The Author(s) 2013</copyright-statement>
<license license-type="OpenAccess">
<license-p>
<bold>Open Access</bold>
This article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited.</license-p>
</license>
</permissions>
<abstract id="Abs1">
<sec>
<title>Summary</title>
<p>This report describes epidemiology, burden, and treatment of osteoporosis in each of the 27 countries of the European Union (EU27).</p>
</sec>
<sec>
<title>Introduction</title>
<p>In 2010, 22 million women and 5.5 million men were estimated to have osteoporosis in the EU; and 3.5 million new fragility fractures were sustained, comprising 620,000 hip fractures, 520,000 vertebral fractures, 560,000 forearm fractures and 1,800,000 other fractures. The economic burden of incident and prior fragility fractures was estimated at € 37 billion. Previous and incident fractures also accounted for 1,180,000 quality-adjusted life years lost during 2010. The costs are expected to increase by 25 % in 2025. The majority of individuals who have sustained an osteoporosis-related fracture or who are at high risk of fracture are untreated and the number of patients on treatment is declining. The aim of this report was to characterize the burden of osteoporosis in each of the EU27 countries in 2010 and beyond.</p>
</sec>
<sec>
<title>Methods</title>
<p>The data on fracture incidence and costs of fractures in the EU27 were taken from a concurrent publication in this journal (Osteoporosis in the European Union: Medical Management, Epidemiology and Economic Burden) and country specific information extracted.</p>
</sec>
<sec>
<title>Results</title>
<p>The clinical and economic burden of osteoporotic fractures in 2010 is given for each of the 27 countries of the EU. The costs are expected to increase on average by 25 % in 2025. The majority of individuals who have sustained an osteoporosis-related fracture or who are at high risk of fracture are untreated and the number of patients on treatment is declining.</p>
</sec>
<sec>
<title>Conclusions</title>
<p>In spite of the high cost of osteoporosis, a substantial treatment gap and projected increase of the economic burden driven by aging populations, the use of pharmacological prevention of osteoporosis has decreased in recent years, suggesting that a change in healthcare policy concerning the disease is warranted.</p>
</sec>
</abstract>
<kwd-group xml:lang="en">
<title>Keywords</title>
<kwd>Epidemiology</kwd>
<kwd>Fracture</kwd>
<kwd>Economic burden</kwd>
<kwd>European Union</kwd>
<kwd>Treatment</kwd>
<kwd>Health Technology Assessment</kwd>
</kwd-group>
<custom-meta-group>
<custom-meta>
<meta-name>issue-copyright-statement</meta-name>
<meta-value>© International Osteoporosis Foundation and National Osteoporosis Foundation 2013</meta-value>
</custom-meta>
</custom-meta-group>
</article-meta>
</front>
</pmc>
<affiliations>
<list>
<country>
<li>Royaume-Uni</li>
<li>Suisse</li>
<li>Suède</li>
</country>
<region>
<li>Angleterre</li>
<li>Oxfordshire</li>
<li>Svealand</li>
</region>
<settlement>
<li>Oxford</li>
<li>Stockholm</li>
</settlement>
<orgName>
<li>Université d'Oxford</li>
</orgName>
</list>
<tree>
<country name="Suède">
<region name="Svealand">
<name sortKey="Svedbom, A" sort="Svedbom, A" uniqKey="Svedbom A" first="A." last="Svedbom">A. Svedbom</name>
</region>
<name sortKey="Hernlund, E" sort="Hernlund, E" uniqKey="Hernlund E" first="E." last="Hernlund">E. Hernlund</name>
<name sortKey="Iverg Rd, M" sort="Iverg Rd, M" uniqKey="Iverg Rd M" first="M." last="Iverg Rd">M. Iverg Rd</name>
<name sortKey="Jonsson, B" sort="Jonsson, B" uniqKey="Jonsson B" first="B." last="Jönsson">B. Jönsson</name>
</country>
<country name="Royaume-Uni">
<noRegion>
<name sortKey="Compston, J" sort="Compston, J" uniqKey="Compston J" first="J." last="Compston">J. Compston</name>
</noRegion>
<name sortKey="Cooper, C" sort="Cooper, C" uniqKey="Cooper C" first="C." last="Cooper">C. Cooper</name>
<name sortKey="Cooper, C" sort="Cooper, C" uniqKey="Cooper C" first="C." last="Cooper">C. Cooper</name>
<name sortKey="Kanis, J A" sort="Kanis, J A" uniqKey="Kanis J" first="J. A." last="Kanis">J. A. Kanis</name>
<name sortKey="Mccloskey, E V" sort="Mccloskey, E V" uniqKey="Mccloskey E" first="E. V." last="Mccloskey">E. V. Mccloskey</name>
<name sortKey="Mccloskey, E V" sort="Mccloskey, E V" uniqKey="Mccloskey E" first="E. V." last="Mccloskey">E. V. Mccloskey</name>
</country>
<country name="Suisse">
<noRegion>
<name sortKey="Stenmark, J" sort="Stenmark, J" uniqKey="Stenmark J" first="J." last="Stenmark">J. Stenmark</name>
</noRegion>
</country>
</tree>
</affiliations>
</record>

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