Education Differences in Life Expectancy With Cognitive Impairment
Identifieur interne : 001127 ( Istex/Corpus ); précédent : 001126; suivant : 001128Education Differences in Life Expectancy With Cognitive Impairment
Auteurs : Fiona E. Matthews ; Carol Jagger ; Laura L. Miller ; Carol BrayneSource :
- Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences [ 1079-5006 ] ; 2009-01-31.
Abstract
Background Low education has an impact on life expectancy and level of cognition, but little is known on its effect on life expectancy with cognitive impairment. Methods The Medical Research Council Cognitive Function and Ageing Study (MRC CFAS) collected population-based longitudinal data on people aged 65 years and older including measures of education and cognitive impairment, using the Mini-Mental State Examination (MMSE), for five geographically diverse areas around England and Wales interviewed between 1991 and 2003. Transitions between health states were calculated using Markov chain methods. Life expectancy in different states of cognitive function as measured by MMSE were further explored for different education groups. The effect of fixed and educationally based cut points for cognitive impairment are investigated. Results Life expectancy spent with cognitive impairment is fairly constant with increasing age at around 1.4 years in men and 2.5 years in women, though this reflects a large increase in the proportion of life spent with cognitive impairment. The differences seen between education groups for the proportion of total life with cognitive impairment (men 13% and women 22% of life lived for low education vs men 7% and women 12% in high education group) disappear when education-adjusted cut points are used (10% in men and 17% in women at age 65 for all education groups). Conclusions The results show that there is a substantial amount of life expectancy with cognitive impairment in both men and women. The impairment burden is just as great for those with high education as the lowest educated group.
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DOI: 10.1093/gerona/gln003
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Email: fiona.matthews@mrc-bsu.cam.ac.uk</mods:affiliation></affiliation></author><author><name sortKey="Jagger, Carol" sort="Jagger, Carol" uniqKey="Jagger C" first="Carol" last="Jagger">Carol Jagger</name><affiliation><mods:affiliation>Department of Epidemiology and Public Health, Leicester University, Leicester, United Kingdom</mods:affiliation></affiliation></author><author><name sortKey="Miller, Laura L" sort="Miller, Laura L" uniqKey="Miller L" first="Laura L." last="Miller">Laura L. Miller</name><affiliation><mods:affiliation>MRC Biostatistics Unit, Institute of Public Health, Robinson Way, Cambridge, United Kingdom</mods:affiliation></affiliation></author><author><name sortKey="Brayne, Carol" sort="Brayne, Carol" uniqKey="Brayne C" first="Carol" last="Brayne">Carol Brayne</name><affiliation><mods:affiliation>Department of Health and Primary Care, Institute of Public Health, Robinson Way, Cambridge, United Kingdom</mods:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:11BDBF9F8D8DEADFB350A3A38EE725D40ABD9805</idno><date when="2009" year="2009">2009</date><idno type="doi">10.1093/gerona/gln003</idno><idno type="url">https://api.istex.fr/document/11BDBF9F8D8DEADFB350A3A38EE725D40ABD9805/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">001127</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a">Education Differences in Life Expectancy With Cognitive Impairment</title><author><name sortKey="Matthews, Fiona E" sort="Matthews, Fiona E" uniqKey="Matthews F" first="Fiona E." last="Matthews">Fiona E. Matthews</name><affiliation><mods:affiliation>MRC Biostatistics Unit, Institute of Public Health, Robinson Way, Cambridge, United Kingdom</mods:affiliation></affiliation><affiliation><mods:affiliation>Address correspondence to Fiona Matthews, PhD, MRC Biostatisics Unit, Institute of Public Health Robinson Way, Cambridge CB2 2SR, UK. Email: fiona.matthews@mrc-bsu.cam.ac.uk</mods:affiliation></affiliation></author><author><name sortKey="Jagger, Carol" sort="Jagger, Carol" uniqKey="Jagger C" first="Carol" last="Jagger">Carol Jagger</name><affiliation><mods:affiliation>Department of Epidemiology and Public Health, Leicester University, Leicester, United Kingdom</mods:affiliation></affiliation></author><author><name sortKey="Miller, Laura L" sort="Miller, Laura L" uniqKey="Miller L" first="Laura L." last="Miller">Laura L. Miller</name><affiliation><mods:affiliation>MRC Biostatistics Unit, Institute of Public Health, Robinson Way, Cambridge, United Kingdom</mods:affiliation></affiliation></author><author><name sortKey="Brayne, Carol" sort="Brayne, Carol" uniqKey="Brayne C" first="Carol" last="Brayne">Carol Brayne</name><affiliation><mods:affiliation>Department of Health and Primary Care, Institute of Public Health, Robinson Way, Cambridge, United Kingdom</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j">Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences</title><idno type="ISSN">1079-5006</idno><idno type="eISSN">1758-535X</idno><imprint><publisher>Oxford University Press</publisher><date type="published" when="2009-01-31">2009-01-31</date><biblScope unit="volume">64A</biblScope><biblScope unit="issue">1</biblScope><biblScope unit="page" from="125">125</biblScope><biblScope unit="page" to="131">131</biblScope></imprint><idno type="ISSN">1079-5006</idno></series><idno type="istex">11BDBF9F8D8DEADFB350A3A38EE725D40ABD9805</idno><idno type="DOI">10.1093/gerona/gln003</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">1079-5006</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract">Background Low education has an impact on life expectancy and level of cognition, but little is known on its effect on life expectancy with cognitive impairment. Methods The Medical Research Council Cognitive Function and Ageing Study (MRC CFAS) collected population-based longitudinal data on people aged 65 years and older including measures of education and cognitive impairment, using the Mini-Mental State Examination (MMSE), for five geographically diverse areas around England and Wales interviewed between 1991 and 2003. Transitions between health states were calculated using Markov chain methods. Life expectancy in different states of cognitive function as measured by MMSE were further explored for different education groups. The effect of fixed and educationally based cut points for cognitive impairment are investigated. Results Life expectancy spent with cognitive impairment is fairly constant with increasing age at around 1.4 years in men and 2.5 years in women, though this reflects a large increase in the proportion of life spent with cognitive impairment. The differences seen between education groups for the proportion of total life with cognitive impairment (men 13% and women 22% of life lived for low education vs men 7% and women 12% in high education group) disappear when education-adjusted cut points are used (10% in men and 17% in women at age 65 for all education groups). Conclusions The results show that there is a substantial amount of life expectancy with cognitive impairment in both men and women. The impairment burden is just as great for those with high education as the lowest educated group.</div></front></TEI><istex><corpusName>oup</corpusName><author><json:item><name>Fiona E. Matthews</name><affiliations><json:string>MRC Biostatistics Unit, Institute of Public Health, Robinson Way, Cambridge, United Kingdom</json:string><json:string>Address correspondence to Fiona Matthews, PhD, MRC Biostatisics Unit, Institute of Public Health Robinson Way, Cambridge CB2 2SR, UK. Email: fiona.matthews@mrc-bsu.cam.ac.uk</json:string></affiliations></json:item><json:item><name>Carol Jagger</name><affiliations><json:string>Department of Epidemiology and Public Health, Leicester University, Leicester, United Kingdom</json:string></affiliations></json:item><json:item><name>Laura L. Miller</name><affiliations><json:string>MRC Biostatistics Unit, Institute of Public Health, Robinson Way, Cambridge, United Kingdom</json:string></affiliations></json:item><json:item><name>Carol Brayne</name><affiliations><json:string>Department of Health and Primary Care, Institute of Public Health, Robinson Way, Cambridge, United Kingdom</json:string></affiliations></json:item></author><subject><json:item><lang><json:string>eng</json:string></lang><value>Life expectancy</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>Deprivation</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>cognitive impairment</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>social class</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>education</value></json:item></subject><language><json:string>eng</json:string></language><originalGenre><json:string>research-article</json:string></originalGenre><abstract>Background Low education has an impact on life expectancy and level of cognition, but little is known on its effect on life expectancy with cognitive impairment. Methods The Medical Research Council Cognitive Function and Ageing Study (MRC CFAS) collected population-based longitudinal data on people aged 65 years and older including measures of education and cognitive impairment, using the Mini-Mental State Examination (MMSE), for five geographically diverse areas around England and Wales interviewed between 1991 and 2003. Transitions between health states were calculated using Markov chain methods. Life expectancy in different states of cognitive function as measured by MMSE were further explored for different education groups. The effect of fixed and educationally based cut points for cognitive impairment are investigated. Results Life expectancy spent with cognitive impairment is fairly constant with increasing age at around 1.4 years in men and 2.5 years in women, though this reflects a large increase in the proportion of life spent with cognitive impairment. The differences seen between education groups for the proportion of total life with cognitive impairment (men 13% and women 22% of life lived for low education vs men 7% and women 12% in high education group) disappear when education-adjusted cut points are used (10% in men and 17% in women at age 65 for all education groups). Conclusions The results show that there is a substantial amount of life expectancy with cognitive impairment in both men and women. 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Email: fiona.matthews@mrc-bsu.cam.ac.uk</affiliation></author><author xml:id="author-3"><persName><forename type="first">Carol</forename><surname>Jagger</surname></persName><affiliation>Department of Epidemiology and Public Health, Leicester University, Leicester, United Kingdom</affiliation></author><author xml:id="author-4"><persName><forename type="first">Laura L.</forename><surname>Miller</surname></persName><affiliation>MRC Biostatistics Unit, Institute of Public Health, Robinson Way, Cambridge, United Kingdom</affiliation></author><author xml:id="author-5"><persName><forename type="first">Carol</forename><surname>Brayne</surname></persName><affiliation>Department of Health and Primary Care, Institute of Public Health, Robinson Way, Cambridge, United Kingdom</affiliation></author></analytic><monogr><title level="j">Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences</title><idno type="pISSN">1079-5006</idno><idno type="eISSN">1758-535X</idno><imprint><publisher>Oxford University Press</publisher><date type="published" when="2009-01-31"></date><biblScope unit="volume">64A</biblScope><biblScope unit="issue">1</biblScope><biblScope unit="page" from="125">125</biblScope><biblScope unit="page" to="131">131</biblScope></imprint></monogr><idno type="istex">11BDBF9F8D8DEADFB350A3A38EE725D40ABD9805</idno><idno type="DOI">10.1093/gerona/gln003</idno></biblStruct></sourceDesc></fileDesc><profileDesc><creation><date>2009-01-31</date></creation><langUsage><language ident="en">en</language></langUsage><abstract><p>Background Low education has an impact on life expectancy and level of cognition, but little is known on its effect on life expectancy with cognitive impairment. Methods The Medical Research Council Cognitive Function and Ageing Study (MRC CFAS) collected population-based longitudinal data on people aged 65 years and older including measures of education and cognitive impairment, using the Mini-Mental State Examination (MMSE), for five geographically diverse areas around England and Wales interviewed between 1991 and 2003. Transitions between health states were calculated using Markov chain methods. Life expectancy in different states of cognitive function as measured by MMSE were further explored for different education groups. The effect of fixed and educationally based cut points for cognitive impairment are investigated. Results Life expectancy spent with cognitive impairment is fairly constant with increasing age at around 1.4 years in men and 2.5 years in women, though this reflects a large increase in the proportion of life spent with cognitive impairment. The differences seen between education groups for the proportion of total life with cognitive impairment (men 13% and women 22% of life lived for low education vs men 7% and women 12% in high education group) disappear when education-adjusted cut points are used (10% in men and 17% in women at age 65 for all education groups). Conclusions The results show that there is a substantial amount of life expectancy with cognitive impairment in both men and women. The impairment burden is just as great for those with high education as the lowest educated group.</p></abstract><textClass><keywords scheme="keyword"><list><head>keywords</head><item><term>Life expectancy</term></item><item><term>Deprivation</term></item><item><term>cognitive impairment</term></item><item><term>social class</term></item><item><term>education</term></item></list></keywords></textClass></profileDesc><revisionDesc><change when="2009-01-31">Created</change><change when="2009-01-31">Published</change><change xml:id="refBibs-istex" who="#ISTEX-API" when="2016-10-14">References added</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><original>false</original><mimetype>text/plain</mimetype><extension>txt</extension><uri>https://api.istex.fr/document/11BDBF9F8D8DEADFB350A3A38EE725D40ABD9805/fulltext/txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="corpus oup" wicri:toSee="no header"><istex:docType PUBLIC="-//NLM//DTD Journal Publishing DTD v2.3 20070202//EN" URI="journalpublishing.dtd" name="istex:docType"></istex:docType><istex:document><article article-type="research-article"><front><journal-meta><journal-id journal-id-type="hwp">gerona</journal-id><journal-id journal-id-type="publisher-id">gerona</journal-id><journal-title>Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences</journal-title><issn pub-type="epub">1758-535X</issn><issn pub-type="ppub">1079-5006</issn><publisher><publisher-name>Oxford University Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.1093/gerona/gln003</article-id><article-categories><subj-group subj-group-type="heading"><subject>Journal of Gerontology: Medical Sciences</subject><subj-group><subject>Articles</subject></subj-group></subj-group></article-categories><title-group><article-title>Education Differences in Life Expectancy With Cognitive Impairment</article-title></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name><surname>Matthews</surname><given-names>Fiona E.</given-names></name><xref ref-type="aff" rid="aff1">1</xref></contrib><contrib contrib-type="author"><name><surname>Jagger</surname><given-names>Carol</given-names></name><xref ref-type="aff" rid="aff2">2</xref></contrib><contrib contrib-type="author"><name><surname>Miller</surname><given-names>Laura L.</given-names></name><xref ref-type="aff" rid="aff1">1</xref></contrib><contrib contrib-type="author"><name><surname>Brayne</surname><given-names>Carol</given-names></name><xref ref-type="aff" rid="aff3">3</xref></contrib><contrib contrib-type="author"><collab>MRC CFAS</collab><xref ref-type="aff" rid="aff4">4</xref></contrib></contrib-group><aff id="aff1"><label>1</label>MRC Biostatistics Unit, Institute of Public Health, Robinson Way, Cambridge, United Kingdom</aff><aff id="aff2"><label>2</label>Department of Epidemiology and Public Health, Leicester University, Leicester, United Kingdom</aff><aff id="aff3"><label>3</label>Department of Health and Primary Care, Institute of Public Health, Robinson Way, Cambridge, United Kingdom</aff><aff id="aff4"><label>4</label>See <ext-link ext-link-type="uri" xlink:href="http://www.cfas.ac.uk">http://www.cfas.ac.uk.</ext-link></aff><author-notes><corresp>Address correspondence to Fiona Matthews, PhD, MRC Biostatisics Unit, Institute of Public Health Robinson Way, Cambridge CB2 2SR, UK. Email: <email>fiona.matthews@mrc-bsu.cam.ac.uk</email></corresp><fn><p><italic>Decision Editor: Luigi Ferrucci, MD, PhD</italic></p></fn></author-notes><pub-date pub-type="epub-ppub"><month>1</month><year>2009</year></pub-date><pub-date pub-type="epub"><day>31</day><month>1</month><year>2009</year></pub-date><volume>64A</volume><issue>1</issue><fpage>125</fpage><lpage>131</lpage><history><date date-type="received"><day>13</day><month>6</month><year>2007</year></date><date date-type="accepted"><day>10</day><month>4</month><year>2008</year></date></history><permissions><copyright-statement>© 2009 The Author(s).</copyright-statement><copyright-year>2009</copyright-year><license license-type="open-access"><p>This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.</p></license></permissions><abstract><sec><title>Background</title><p>Low education has an impact on life expectancy and level of cognition, but little is known on its effect on life expectancy with cognitive impairment.</p></sec><sec><title>Methods</title><p>The Medical Research Council Cognitive Function and Ageing Study (MRC CFAS) collected population-based longitudinal data on people aged 65 years and older including measures of education and cognitive impairment, using the Mini-Mental State Examination (MMSE), for five geographically diverse areas around England and Wales interviewed between 1991 and 2003. Transitions between health states were calculated using Markov chain methods. Life expectancy in different states of cognitive function as measured by MMSE were further explored for different education groups. The effect of fixed and educationally based cut points for cognitive impairment are investigated.</p></sec><sec><title>Results</title><p>Life expectancy spent with cognitive impairment is fairly constant with increasing age at around 1.4 years in men and 2.5 years in women, though this reflects a large increase in the proportion of life spent with cognitive impairment. The differences seen between education groups for the proportion of total life with cognitive impairment (men 13% and women 22% of life lived for low education vs men 7% and women 12% in high education group) disappear when education-adjusted cut points are used (10% in men and 17% in women at age 65 for all education groups).</p></sec><sec><title>Conclusions</title><p>The results show that there is a substantial amount of life expectancy with cognitive impairment in both men and women. The impairment burden is just as great for those with high education as the lowest educated group.</p></sec></abstract><kwd-group><kwd>Life expectancy</kwd><kwd>Deprivation</kwd><kwd>cognitive impairment</kwd><kwd>social class</kwd><kwd>education</kwd></kwd-group></article-meta></front></article></istex:document></istex:metadataXml><mods version="3.6"><titleInfo><title>Education Differences in Life Expectancy With Cognitive Impairment</title></titleInfo><titleInfo type="alternative" contentType="CDATA"><title>Education Differences in Life Expectancy With Cognitive Impairment</title></titleInfo><name type="corporate"><namePart>MRC CFAS</namePart></name><name type="personal"><namePart type="given">Fiona E.</namePart><namePart type="family">Matthews</namePart><affiliation>MRC Biostatistics Unit, Institute of Public Health, Robinson Way, Cambridge, United Kingdom</affiliation><affiliation>Address correspondence to Fiona Matthews, PhD, MRC Biostatisics Unit, Institute of Public Health Robinson Way, Cambridge CB2 2SR, UK. Email: fiona.matthews@mrc-bsu.cam.ac.uk</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Carol</namePart><namePart type="family">Jagger</namePart><affiliation>Department of Epidemiology and Public Health, Leicester University, Leicester, United Kingdom</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Laura L.</namePart><namePart type="family">Miller</namePart><affiliation>MRC Biostatistics Unit, Institute of Public Health, Robinson Way, Cambridge, United Kingdom</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Carol</namePart><namePart type="family">Brayne</namePart><affiliation>Department of Health and Primary Care, Institute of Public Health, Robinson Way, Cambridge, United Kingdom</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="research-article" displayLabel="research-article"></genre><originInfo><publisher>Oxford University Press</publisher><dateIssued encoding="w3cdtf">2009-01-31</dateIssued><dateCreated encoding="w3cdtf">2009-01-31</dateCreated><copyrightDate encoding="w3cdtf">2009</copyrightDate></originInfo><language><languageTerm type="code" authority="iso639-2b">eng</languageTerm><languageTerm type="code" authority="rfc3066">en</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType></physicalDescription><abstract>Background Low education has an impact on life expectancy and level of cognition, but little is known on its effect on life expectancy with cognitive impairment. Methods The Medical Research Council Cognitive Function and Ageing Study (MRC CFAS) collected population-based longitudinal data on people aged 65 years and older including measures of education and cognitive impairment, using the Mini-Mental State Examination (MMSE), for five geographically diverse areas around England and Wales interviewed between 1991 and 2003. Transitions between health states were calculated using Markov chain methods. Life expectancy in different states of cognitive function as measured by MMSE were further explored for different education groups. The effect of fixed and educationally based cut points for cognitive impairment are investigated. Results Life expectancy spent with cognitive impairment is fairly constant with increasing age at around 1.4 years in men and 2.5 years in women, though this reflects a large increase in the proportion of life spent with cognitive impairment. The differences seen between education groups for the proportion of total life with cognitive impairment (men 13% and women 22% of life lived for low education vs men 7% and women 12% in high education group) disappear when education-adjusted cut points are used (10% in men and 17% in women at age 65 for all education groups). Conclusions The results show that there is a substantial amount of life expectancy with cognitive impairment in both men and women. The impairment burden is just as great for those with high education as the lowest educated group.</abstract><note type="footnotes">Decision Editor: Luigi Ferrucci, MD, PhD</note><subject><genre>keywords</genre><topic>Life expectancy</topic><topic>Deprivation</topic><topic>cognitive impairment</topic><topic>social class</topic><topic>education</topic></subject><relatedItem type="host"><titleInfo><title>Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences</title></titleInfo><genre type="journal">journal</genre><identifier type="ISSN">1079-5006</identifier><identifier type="eISSN">1758-535X</identifier><identifier type="PublisherID">gerona</identifier><identifier type="PublisherID-hwp">gerona</identifier><part><date>2009</date><detail type="volume"><caption>vol.</caption><number>64A</number></detail><detail type="issue"><caption>no.</caption><number>1</number></detail><extent unit="pages"><start>125</start><end>131</end></extent></part></relatedItem><identifier type="istex">11BDBF9F8D8DEADFB350A3A38EE725D40ABD9805</identifier><identifier type="DOI">10.1093/gerona/gln003</identifier><accessCondition type="use and reproduction" contentType="open-access">This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.</accessCondition><recordInfo><recordContentSource>OUP</recordContentSource></recordInfo></mods></metadata><covers><json:item><original>true</original><mimetype>image/tiff</mimetype><extension>tiff</extension><uri>https://api.istex.fr/document/11BDBF9F8D8DEADFB350A3A38EE725D40ABD9805/covers/tiff</uri></json:item></covers><annexes><json:item><original>true</original><mimetype>image/jpeg</mimetype><extension>jpeg</extension><uri>https://api.istex.fr/document/11BDBF9F8D8DEADFB350A3A38EE725D40ABD9805/annexes/jpeg</uri></json:item><json:item><original>true</original><mimetype>image/gif</mimetype><extension>gif</extension><uri>https://api.istex.fr/document/11BDBF9F8D8DEADFB350A3A38EE725D40ABD9805/annexes/gif</uri></json:item><json:item><original>true</original><mimetype>application/pdf</mimetype><extension>pdf</extension><uri>https://api.istex.fr/document/11BDBF9F8D8DEADFB350A3A38EE725D40ABD9805/annexes/pdf</uri></json:item></annexes><enrichments><istex:catWosTEI uri="https://api.istex.fr/document/11BDBF9F8D8DEADFB350A3A38EE725D40ABD9805/enrichments/catWos"><teiHeader><profileDesc><textClass><classCode scheme="WOS">GERONTOLOGY</classCode><classCode scheme="WOS">GERIATRICS & GERONTOLOGY</classCode></textClass></profileDesc></teiHeader></istex:catWosTEI><json:item><type>refBibs</type><uri>https://api.istex.fr/document/11BDBF9F8D8DEADFB350A3A38EE725D40ABD9805/enrichments/refBibs</uri></json:item></enrichments><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
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