1 Nomenclature of dyspepsia, dyspepsia subgroups and functional dyspepsia: Clarifying the concepts
Identifieur interne : 001656 ( Istex/Checkpoint ); précédent : 001655; suivant : 0016571 Nomenclature of dyspepsia, dyspepsia subgroups and functional dyspepsia: Clarifying the concepts
Auteurs : Gerald Holtmann [Allemagne] ; Vincenzo Stanghellini [Italie] ; Nicholas J. Talley [Australie]Source :
- Bailliere's Clinical Gastroenterology [ 0950-3528 ] ; 1998.
Abstract
There is international agreement that dyspepsia refers to pain or discomfort centred in the upper abdomen. However, the term ‘discomfort’ has been variably defined. While other symptoms may often be simultaneously present, gastro-oesophageal reflux disease can usually be clearly distinguished by the presence of predominant heartburn. Dyspepsia is a frequent reason for consultation in primary care and in gastrointestinal practice. With the widespread availability and utilization of endoscopy, it has become evident that a structural (or organic) explanation is found in only a minority of patients presenting with dyspepsia. Operationally, functional dyspepsia is defined as persistent or recurrent dyspepsia for 3 or more months in the absence of a clinically identifiable structural disease causing the symptoms. It has been proposed, based on symptoms, that functional dyspepsia be subdivided into symptom subgroups to promote patient homogeneity. The initially proposed ‘clustering’ of symptoms into ulcer-like and dysmotility-like functional dyspepsia has proved a dismal failure because of the considerable overlap observed, the lack of stability over time and the failure to identify robust pathophysiological abnormalities or responses to therapy. A subcategorization based upon the most bothersome symptom is theoretically more attractive but needs to be prospectively and rigorously tested.
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DOI: 10.1016/S0950-3528(98)90015-X
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Talley</name><affiliation wicri:level="1"><country xml:lang="fr">Australie</country><wicri:regionArea>Department of Medicine, University of Sydney, Clinical Sciences Building, Nepean Hospital, PO Box 63, Penrith, NSW</wicri:regionArea><wicri:noRegion>NSW</wicri:noRegion></affiliation></author></analytic><monogr></monogr><series><title level="j">Bailliere's Clinical Gastroenterology</title><title level="j" type="abbrev">BACG</title><idno type="ISSN">0950-3528</idno><imprint><publisher>ELSEVIER</publisher><date type="published" when="1998">1998</date><biblScope unit="volume">12</biblScope><biblScope unit="issue">3</biblScope><biblScope unit="page" from="417">417</biblScope><biblScope unit="page" to="433">433</biblScope></imprint><idno type="ISSN">0950-3528</idno></series><idno type="istex">D42D1B2065D529210567B4899A56BEB0730306FE</idno><idno type="DOI">10.1016/S0950-3528(98)90015-X</idno><idno type="PII">S0950-3528(98)90015-X</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0950-3528</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">There is international agreement that dyspepsia refers to pain or discomfort centred in the upper abdomen. However, the term ‘discomfort’ has been variably defined. While other symptoms may often be simultaneously present, gastro-oesophageal reflux disease can usually be clearly distinguished by the presence of predominant heartburn. Dyspepsia is a frequent reason for consultation in primary care and in gastrointestinal practice. With the widespread availability and utilization of endoscopy, it has become evident that a structural (or organic) explanation is found in only a minority of patients presenting with dyspepsia. Operationally, functional dyspepsia is defined as persistent or recurrent dyspepsia for 3 or more months in the absence of a clinically identifiable structural disease causing the symptoms. It has been proposed, based on symptoms, that functional dyspepsia be subdivided into symptom subgroups to promote patient homogeneity. The initially proposed ‘clustering’ of symptoms into ulcer-like and dysmotility-like functional dyspepsia has proved a dismal failure because of the considerable overlap observed, the lack of stability over time and the failure to identify robust pathophysiological abnormalities or responses to therapy. A subcategorization based upon the most bothersome symptom is theoretically more attractive but needs to be prospectively and rigorously tested.</div></front></TEI><affiliations><list><country><li>Allemagne</li><li>Australie</li><li>Italie</li></country></list><tree><country name="Allemagne"><noRegion><name sortKey="Holtmann, Gerald" sort="Holtmann, Gerald" uniqKey="Holtmann G" first="Gerald" last="Holtmann">Gerald Holtmann</name></noRegion></country><country name="Italie"><noRegion><name sortKey="Stanghellini, Vincenzo" sort="Stanghellini, Vincenzo" uniqKey="Stanghellini V" first="Vincenzo" last="Stanghellini">Vincenzo Stanghellini</name></noRegion></country><country name="Australie"><noRegion><name sortKey="Talley, Nicholas J" sort="Talley, Nicholas J" uniqKey="Talley N" first="Nicholas J." last="Talley">Nicholas J. Talley</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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