A Graph-Based Recovery and Decomposition of Swanson’s Hypothesis using Semantic Predications
Identifieur interne : 000132 ( Pmc/Corpus ); précédent : 000131; suivant : 000133A Graph-Based Recovery and Decomposition of Swanson’s Hypothesis using Semantic Predications
Auteurs : Delroy Cameron ; Olivier Bodenreider ; Hima Yalamanchili ; Tu Danh ; Sreeram Vallabhaneni ; Krishnaprasad Thirunarayan ; Amit P. Sheth ; Thomas C. RindfleschSource :
- Journal of biomedical informatics [ 1532-0464 ] ; 2012.
Abstract
This paper presents a methodology for recovering and decomposing Swanson’s
Semantic predications obtained from biomedical literature allow the construction of labeled directed graphs which contain various associations among concepts from the literature. By aggregating such associations into informative subgraphs, some of the relevant details originally articulated by Swanson has been uncovered. However, by leveraging background knowledge to bridge important knowledge gaps in the literature, a methodology for semi-automatically capturing the detailed associations originally explicated in natural language by Swanson has been developed.
Our methodology not only recovered the 3 associations commonly recognized as Swanson’s Hypothesis, but also decomposed them into an additional 16 detailed associations, formulated as chains of semantic predications. Altogether, 14 out of the 19 associations that can be attributed to Swanson were retrieved using our approach. To the best of our knowledge, such an in-depth recovery and decomposition of Swanson’s Hypothesis has never been attempted.
In this work therefore, we presented a methodology for semi- automatically recovering and decomposing Swanson’s
Url:
DOI: 10.1016/j.jbi.2012.09.004
PubMed: 23026233
PubMed Central: 4031661
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