Comparison of desflurane with sevoflurane for the incidence of oculocardiac reflex in children undergoing strabismus surgery
Identifieur interne : 000209 ( Istex/Curation ); précédent : 000208; suivant : 000210Comparison of desflurane with sevoflurane for the incidence of oculocardiac reflex in children undergoing strabismus surgery
Auteurs : A. Y. Oh [Corée du Sud] ; M. J. Yun [Corée du Sud] ; H. J. Kim [Corée du Sud] ; H. S. Kim [Corée du Sud]Source :
- British Journal of Anaesthesia [ 0007-0912 ] ; 2007-08.
Abstract
Background The oculocardiac reflex (OCR) is frequently observed during strabismus surgery. This study was designed to evaluate and compare the effect of sevoflurane and desflurane on the incidence of OCR. Methods After obtaining Institutional Review Board approval and informed consent from parents, we enrolled 237 paediatric patients, aged 210 yr, undergoing strabismus surgery. No premedication was given. Anaesthesia was induced with thiopental and rocuronium. Patients were randomly allocated to one of the two anaesthetic regimens. Group S (n 123) received sevoflurane and Group D (n 114) received desflurane, both with 60 N2O/O2 for maintenance of anaesthesia. The OCR was defined as a 20 decrease in heart rate (HR) from baseline values obtained immediately before muscle manipulation. If the HR did not increase after release of muscle tension, atropine 0.01 mg kg1 was administered. Results There were no significant differences between the two groups in age, sex, body weight, and the number of muscles operated upon. The mean values of baseline HR were 123 (16) min1 in Group S and 121 (18) in Group D (NS). The minimum HR was 106 (22) min1 in Group S and 103 (21) in Group D (NS). There was no difference in the incidence of OCR between sevoflurane (26.0) and desflurane (28.0) anaesthesia. Conclusions Both agents can be used safely during strabismus surgery in paediatric patients.
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DOI: 10.1093/bja/aem145
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<front><div type="abstract">Background The oculocardiac reflex (OCR) is frequently observed during strabismus surgery. This study was designed to evaluate and compare the effect of sevoflurane and desflurane on the incidence of OCR. Methods After obtaining Institutional Review Board approval and informed consent from parents, we enrolled 237 paediatric patients, aged 210 yr, undergoing strabismus surgery. No premedication was given. Anaesthesia was induced with thiopental and rocuronium. Patients were randomly allocated to one of the two anaesthetic regimens. Group S (n 123) received sevoflurane and Group D (n 114) received desflurane, both with 60 N2O/O2 for maintenance of anaesthesia. The OCR was defined as a 20 decrease in heart rate (HR) from baseline values obtained immediately before muscle manipulation. If the HR did not increase after release of muscle tension, atropine 0.01 mg kg1 was administered. Results There were no significant differences between the two groups in age, sex, body weight, and the number of muscles operated upon. The mean values of baseline HR were 123 (16) min1 in Group S and 121 (18) in Group D (NS). The minimum HR was 106 (22) min1 in Group S and 103 (21) in Group D (NS). There was no difference in the incidence of OCR between sevoflurane (26.0) and desflurane (28.0) anaesthesia. Conclusions Both agents can be used safely during strabismus surgery in paediatric patients.</div>
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