Interinstitutional experience in verification of external photon dose calculations
Identifieur interne : 001044 ( Istex/Corpus ); précédent : 001043; suivant : 001045Interinstitutional experience in verification of external photon dose calculations
Auteurs : Mary Ellen Masterson ; Glenn Barest ; Chen-Shou Chui ; Karen P. Doppke ; Robert D. Epperson ; William B. Harms ; Kenneth E. Krippner ; Radhe Mohan ; Eric D. Slessinger ; Marc R. Sontag ; Marcia M. Urie ; Robert E. Wallace ; John W. WongSource :
- International Journal of Radiation Oncology, Biology, Physics [ 0360-3016 ] ; 1991.
Abstract
Under the auspices of NCI contracts, four institutions have collaborated to assess the accuracy of the pixel-based dose calculation methods they employ for external photon treatment planning. The approach relied on comparing calculations using each group's algorithm with measurements in phantoms of increasing complexity. The first set of measurements consisted of ionization chamber measurements in water phantoms in normally incident square fields, an elongated field, a wedged field, a blocked field, and an obliquely incident beam. The second group of measurements was carried out using thermoluminescent dosimeters in phantoms designed to investigate the effects of surface curvature, high density heterogeneities, and low density heterogeneities. The final study tested the entire treatment planning system, including CT data conversion, in an anthropomorphic phantom. Overall, good agreement between calculation and measurements was found for all algorithms. Regions in which discrepancies were observed are pointed out, areas for algorithm improvement are identified and the clinical import of algorithm accuracy is discussed.
Url:
DOI: 10.1016/0360-3016(91)90166-2
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Doppke</name><affiliation><mods:affiliation>Massachusetts General Hospital, Dept. of Radiation Medicine, Boston, MA 02114, USA</mods:affiliation></affiliation></author><author><name sortKey="Epperson, Robert D" sort="Epperson, Robert D" uniqKey="Epperson R" first="Robert D." last="Epperson">Robert D. Epperson</name><affiliation><mods:affiliation>University of Pennsylvania School of Medicine and the Fox Chase Cancer Center, Philadelphia, PA 19111, USA</mods:affiliation></affiliation></author><author><name sortKey="Harms, William B" sort="Harms, William B" uniqKey="Harms W" first="William B." last="Harms">William B. Harms</name><affiliation><mods:affiliation>Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO 63110, USA</mods:affiliation></affiliation></author><author><name sortKey="Krippner, Kenneth E" sort="Krippner, Kenneth E" uniqKey="Krippner K" first="Kenneth E." last="Krippner">Kenneth E. Krippner</name><affiliation><mods:affiliation>University of Pennsylvania School of Medicine and the Fox Chase Cancer Center, Philadelphia, PA 19111, USAMemorial Sloan-Kettering Cancer Center, New York, NY 10021, USAMallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO 63110, USAMassachusetts General Hospital, Dept. of Radiation Medicine, Boston, MA 02114, USAHarvard Medical School, USA</mods:affiliation></affiliation></author><author><name sortKey="Mohan, Radhe" sort="Mohan, Radhe" uniqKey="Mohan R" first="Radhe" last="Mohan">Radhe Mohan</name><affiliation><mods:affiliation>Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA</mods:affiliation></affiliation></author><author><name sortKey="Slessinger, Eric D" sort="Slessinger, Eric D" uniqKey="Slessinger E" first="Eric D." last="Slessinger">Eric D. Slessinger</name><affiliation><mods:affiliation>Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO 63110, USA</mods:affiliation></affiliation></author><author><name sortKey="Sontag, Marc R" sort="Sontag, Marc R" uniqKey="Sontag M" first="Marc R." last="Sontag">Marc R. Sontag</name><affiliation><mods:affiliation>University of Pennsylvania School of Medicine and the Fox Chase Cancer Center, Philadelphia, PA 19111, USA</mods:affiliation></affiliation></author><author><name sortKey="Urie, Marcia M" sort="Urie, Marcia M" uniqKey="Urie M" first="Marcia M." last="Urie">Marcia M. Urie</name><affiliation><mods:affiliation>Massachusetts General Hospital, Dept. of Radiation Medicine, Boston, MA 02114, USA</mods:affiliation></affiliation></author><author><name sortKey="Wallace, Robert E" sort="Wallace, Robert E" uniqKey="Wallace R" first="Robert E." last="Wallace">Robert E. Wallace</name><affiliation><mods:affiliation>University of Pennsylvania School of Medicine and the Fox Chase Cancer Center, Philadelphia, PA 19111, USA</mods:affiliation></affiliation></author><author><name sortKey="Wong, John W" sort="Wong, John W" uniqKey="Wong J" first="John W." last="Wong">John W. Wong</name><affiliation><mods:affiliation>Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO 63110, USA</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j">International Journal of Radiation Oncology, Biology, Physics</title><title level="j" type="abbrev">ROB</title><idno type="ISSN">0360-3016</idno><imprint><publisher>ELSEVIER</publisher><date type="published" when="1991">1991</date><biblScope unit="volume">21</biblScope><biblScope unit="issue">1</biblScope><biblScope unit="page" from="37">37</biblScope><biblScope unit="page" to="58">58</biblScope></imprint><idno type="ISSN">0360-3016</idno></series><idno type="istex">A665AE7F4DFAC2B71248C68444084AC1DCFD0C9D</idno><idno type="DOI">10.1016/0360-3016(91)90166-2</idno><idno type="PII">0360-3016(91)90166-2</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0360-3016</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Under the auspices of NCI contracts, four institutions have collaborated to assess the accuracy of the pixel-based dose calculation methods they employ for external photon treatment planning. The approach relied on comparing calculations using each group's algorithm with measurements in phantoms of increasing complexity. The first set of measurements consisted of ionization chamber measurements in water phantoms in normally incident square fields, an elongated field, a wedged field, a blocked field, and an obliquely incident beam. The second group of measurements was carried out using thermoluminescent dosimeters in phantoms designed to investigate the effects of surface curvature, high density heterogeneities, and low density heterogeneities. The final study tested the entire treatment planning system, including CT data conversion, in an anthropomorphic phantom. Overall, good agreement between calculation and measurements was found for all algorithms. Regions in which discrepancies were observed are pointed out, areas for algorithm improvement are identified and the clinical import of algorithm accuracy is discussed.</div></front></TEI><istex><corpusName>elsevier</corpusName><author><json:item><name>Mary Ellen Masterson M.S.</name><affiliations><json:string>Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA</json:string></affiliations></json:item><json:item><name>Glenn Barest B.S.</name><affiliations><json:string>Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA</json:string></affiliations></json:item><json:item><name>Chen-Shou Chui Ph.D.</name><affiliations><json:string>Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA</json:string></affiliations></json:item><json:item><name>Karen P. Doppke M.S.</name><affiliations><json:string>Massachusetts General Hospital, Dept. of Radiation Medicine, Boston, MA 02114, USA</json:string></affiliations></json:item><json:item><name>Robert D. Epperson B.A.</name><affiliations><json:string>University of Pennsylvania School of Medicine and the Fox Chase Cancer Center, Philadelphia, PA 19111, USA</json:string></affiliations></json:item><json:item><name>William B. Harms B.S.</name><affiliations><json:string>Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO 63110, USA</json:string></affiliations></json:item><json:item><name>Kenneth E. Krippner M.S.</name><affiliations><json:string>University of Pennsylvania School of Medicine and the Fox Chase Cancer Center, Philadelphia, PA 19111, USAMemorial Sloan-Kettering Cancer Center, New York, NY 10021, USAMallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO 63110, USAMassachusetts General Hospital, Dept. of Radiation Medicine, Boston, MA 02114, USAHarvard Medical School, USA</json:string></affiliations></json:item><json:item><name>Radhe Mohan Ph.D.</name><affiliations><json:string>Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA</json:string></affiliations></json:item><json:item><name>Eric D. Slessinger M.S.</name><affiliations><json:string>Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO 63110, USA</json:string></affiliations></json:item><json:item><name>Marc R. Sontag Ph.D.</name><affiliations><json:string>University of Pennsylvania School of Medicine and the Fox Chase Cancer Center, Philadelphia, PA 19111, USA</json:string></affiliations></json:item><json:item><name>Marcia M. Urie Ph.D.</name><affiliations><json:string>Massachusetts General Hospital, Dept. of Radiation Medicine, Boston, MA 02114, USA</json:string></affiliations></json:item><json:item><name>Robert E. Wallace Ph.D.</name><affiliations><json:string>University of Pennsylvania School of Medicine and the Fox Chase Cancer Center, Philadelphia, PA 19111, USA</json:string></affiliations></json:item><json:item><name>John W. Wong Ph.D.</name><affiliations><json:string>Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO 63110, USA</json:string></affiliations></json:item></author><subject><json:item><lang><json:string>eng</json:string></lang><value>External photon treatment planning</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>Dose calculations</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>Algorithm accuracy</value></json:item></subject><language><json:string>eng</json:string></language><abstract>Under the auspices of NCI contracts, four institutions have collaborated to assess the accuracy of the pixel-based dose calculation methods they employ for external photon treatment planning. The approach relied on comparing calculations using each group's algorithm with measurements in phantoms of increasing complexity. The first set of measurements consisted of ionization chamber measurements in water phantoms in normally incident square fields, an elongated field, a wedged field, a blocked field, and an obliquely incident beam. The second group of measurements was carried out using thermoluminescent dosimeters in phantoms designed to investigate the effects of surface curvature, high density heterogeneities, and low density heterogeneities. The final study tested the entire treatment planning system, including CT data conversion, in an anthropomorphic phantom. Overall, good agreement between calculation and measurements was found for all algorithms. Regions in which discrepancies were observed are pointed out, areas for algorithm improvement are identified and the clinical import of algorithm accuracy is discussed.</abstract><qualityIndicators><score>7.384</score><pdfVersion>1.4</pdfVersion><pdfPageSize>598 x 806 pts</pdfPageSize><refBibsNative>true</refBibsNative><keywordCount>3</keywordCount><abstractCharCount>1135</abstractCharCount><pdfWordCount>10980</pdfWordCount><pdfCharCount>65265</pdfCharCount><pdfPageCount>22</pdfPageCount><abstractWordCount>157</abstractWordCount></qualityIndicators><title>Interinstitutional experience in verification of external photon dose 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uri="https://api.istex.fr/document/A665AE7F4DFAC2B71248C68444084AC1DCFD0C9D/fulltext/tei"><teiHeader><fileDesc><titleStmt><title level="a">Interinstitutional experience in verification of external photon dose calculations</title></titleStmt><publicationStmt><authority>ISTEX</authority><publisher>ELSEVIER</publisher><availability><p>ELSEVIER</p></availability><date>1991</date></publicationStmt><notesStmt><note>Supported in part by NCI Contracts N01 CM-47316, N01 CM-47695, N01 CM-47696, and N01 CM-47697.</note><note type="content">Section title: Original contribution</note></notesStmt><sourceDesc><biblStruct type="inbook"><analytic><title level="a">Interinstitutional experience in verification of external photon dose calculations</title><author><persName><forename type="first">Mary Ellen</forename><surname>Masterson</surname></persName><roleName type="degree">M.S.</roleName><note type="biography">Reprint requests to: Mary Ellen Masterson, Memorial Sloan-Kettering Cancer Center, Medical Physics, 1275 York Ave., New York, NY 10021.</note><affiliation>Reprint requests to: Mary Ellen Masterson, Memorial Sloan-Kettering Cancer Center, Medical Physics, 1275 York Ave., New York, NY 10021.</affiliation><affiliation>Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA</affiliation></author><author><persName><forename type="first">Glenn</forename><surname>Barest</surname></persName><roleName type="degree">B.S.</roleName><affiliation>Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA</affiliation></author><author><persName><forename type="first">Chen-Shou</forename><surname>Chui</surname></persName><roleName type="degree">Ph.D.</roleName><affiliation>Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA</affiliation></author><author><persName><forename type="first">Karen P.</forename><surname>Doppke</surname></persName><roleName type="degree">M.S.</roleName><affiliation>Massachusetts General Hospital, Dept. of Radiation Medicine, Boston, MA 02114, USA</affiliation></author><author><persName><forename type="first">Robert D.</forename><surname>Epperson</surname></persName><roleName type="degree">B.A.</roleName><affiliation>University of Pennsylvania School of Medicine and the Fox Chase Cancer Center, Philadelphia, PA 19111, USA</affiliation></author><author><persName><forename type="first">William B.</forename><surname>Harms</surname></persName><roleName type="degree">B.S.</roleName><affiliation>Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO 63110, USA</affiliation></author><author><persName><forename type="first">Kenneth E.</forename><surname>Krippner</surname></persName><roleName type="degree">M.S.</roleName><affiliation>University of Pennsylvania School of Medicine and the Fox Chase Cancer Center, Philadelphia, PA 19111, USAMemorial Sloan-Kettering Cancer Center, New York, NY 10021, USAMallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO 63110, USAMassachusetts General Hospital, Dept. of Radiation Medicine, Boston, MA 02114, USAHarvard Medical School, USA</affiliation></author><author><persName><forename type="first">Radhe</forename><surname>Mohan</surname></persName><roleName type="degree">Ph.D.</roleName><affiliation>Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA</affiliation></author><author><persName><forename type="first">Eric D.</forename><surname>Slessinger</surname></persName><roleName type="degree">M.S.</roleName><affiliation>Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO 63110, USA</affiliation></author><author><persName><forename type="first">Marc R.</forename><surname>Sontag</surname></persName><roleName type="degree">Ph.D.</roleName><affiliation>University of Pennsylvania School of Medicine and the Fox Chase Cancer Center, Philadelphia, PA 19111, USA</affiliation></author><author><persName><forename type="first">Marcia M.</forename><surname>Urie</surname></persName><roleName type="degree">Ph.D.</roleName><affiliation>Massachusetts General Hospital, Dept. of Radiation Medicine, Boston, MA 02114, USA</affiliation></author><author><persName><forename type="first">Robert E.</forename><surname>Wallace</surname></persName><roleName type="degree">Ph.D.</roleName><affiliation>University of Pennsylvania School of Medicine and the Fox Chase Cancer Center, Philadelphia, PA 19111, USA</affiliation></author><author><persName><forename type="first">John W.</forename><surname>Wong</surname></persName><roleName type="degree">Ph.D.</roleName><affiliation>Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO 63110, USA</affiliation></author></analytic><monogr><title level="j">International Journal of Radiation Oncology, Biology, Physics</title><title level="j" type="abbrev">ROB</title><idno type="pISSN">0360-3016</idno><idno type="PII">S0360-3016(00)X0277-5</idno><imprint><publisher>ELSEVIER</publisher><date type="published" when="1991"></date><biblScope unit="volume">21</biblScope><biblScope unit="issue">1</biblScope><biblScope unit="page" from="37">37</biblScope><biblScope unit="page" to="58">58</biblScope></imprint></monogr><idno type="istex">A665AE7F4DFAC2B71248C68444084AC1DCFD0C9D</idno><idno type="DOI">10.1016/0360-3016(91)90166-2</idno><idno type="PII">0360-3016(91)90166-2</idno></biblStruct></sourceDesc></fileDesc><profileDesc><creation><date>1991</date></creation><langUsage><language ident="en">en</language></langUsage><abstract xml:lang="en"><p>Under the auspices of NCI contracts, four institutions have collaborated to assess the accuracy of the pixel-based dose calculation methods they employ for external photon treatment planning. The approach relied on comparing calculations using each group's algorithm with measurements in phantoms of increasing complexity. The first set of measurements consisted of ionization chamber measurements in water phantoms in normally incident square fields, an elongated field, a wedged field, a blocked field, and an obliquely incident beam. The second group of measurements was carried out using thermoluminescent dosimeters in phantoms designed to investigate the effects of surface curvature, high density heterogeneities, and low density heterogeneities. The final study tested the entire treatment planning system, including CT data conversion, in an anthropomorphic phantom. Overall, good agreement between calculation and measurements was found for all algorithms. Regions in which discrepancies were observed are pointed out, areas for algorithm improvement are identified and the clinical import of algorithm accuracy is discussed.</p></abstract><textClass><keywords scheme="keyword"><list><head>Keywords</head><item><term>External photon treatment planning</term></item><item><term>Dose calculations</term></item><item><term>Algorithm accuracy</term></item></list></keywords></textClass></profileDesc><revisionDesc><change when="1991">Published</change></revisionDesc></teiHeader></istex:fulltextTEI></fulltext><metadata><istex:metadataXml wicri:clean="Elsevier, elements deleted: tail"><istex:xmlDeclaration>version="1.0" encoding="UTF-8" </istex:xmlDeclaration><istex:docType PUBLIC="-//ES//DTD journal article DTD version 4.5.2//EN//XML" URI="art452.dtd" name="istex:docType"></istex:docType><istex:document><converted-article version="4.5.2" docsubtype="fla"><item-info><jid>ROB</jid><aid>91901662</aid><ce:pii>0360-3016(91)90166-2</ce:pii><ce:doi>10.1016/0360-3016(91)90166-2</ce:doi><ce:copyright type="unknown" year="1991"></ce:copyright></item-info><head><ce:article-footnote><ce:label>☆</ce:label><ce:note-para>Supported in part by NCI Contracts N01 CM-47316, N01 CM-47695, N01 CM-47696, and N01 CM-47697.</ce:note-para></ce:article-footnote><ce:dochead><ce:textfn>Original contribution</ce:textfn></ce:dochead><ce:title>Interinstitutional experience in verification of external photon dose calculations</ce:title><ce:author-group><ce:author><ce:given-name>Mary Ellen</ce:given-name><ce:surname>Masterson</ce:surname><ce:degrees>M.S.</ce:degrees><ce:cross-ref refid="COR1"><ce:sup>∗</ce:sup></ce:cross-ref><ce:cross-ref refid="AFF2"><ce:sup>2</ce:sup></ce:cross-ref></ce:author><ce:author><ce:given-name>Glenn</ce:given-name><ce:surname>Barest</ce:surname><ce:degrees>B.S.</ce:degrees><ce:cross-ref refid="AFF2"><ce:sup>2</ce:sup></ce:cross-ref></ce:author><ce:author><ce:given-name>Chen-Shou</ce:given-name><ce:surname>Chui</ce:surname><ce:degrees>Ph.D.</ce:degrees><ce:cross-ref refid="AFF2"><ce:sup>2</ce:sup></ce:cross-ref></ce:author><ce:author><ce:given-name>Karen P.</ce:given-name><ce:surname>Doppke</ce:surname><ce:degrees>M.S.</ce:degrees><ce:cross-ref refid="AFF4"><ce:sup>4</ce:sup></ce:cross-ref><ce:cross-ref refid="AFF5"><ce:sup>5</ce:sup></ce:cross-ref></ce:author><ce:author><ce:given-name>Robert D.</ce:given-name><ce:surname>Epperson</ce:surname><ce:degrees>B.A.</ce:degrees><ce:cross-ref refid="AFF1"><ce:sup>1</ce:sup></ce:cross-ref></ce:author><ce:author><ce:given-name>William B.</ce:given-name><ce:surname>Harms</ce:surname><ce:degrees>B.S.</ce:degrees><ce:cross-ref refid="AFF3"><ce:sup>3</ce:sup></ce:cross-ref></ce:author><ce:author><ce:given-name>Kenneth E.</ce:given-name><ce:surname>Krippner</ce:surname><ce:degrees>M.S.</ce:degrees></ce:author><ce:author><ce:given-name>Radhe</ce:given-name><ce:surname>Mohan</ce:surname><ce:degrees>Ph.D.</ce:degrees><ce:cross-ref refid="AFF2"><ce:sup>2</ce:sup></ce:cross-ref></ce:author><ce:author><ce:given-name>Eric D.</ce:given-name><ce:surname>Slessinger</ce:surname><ce:degrees>M.S.</ce:degrees><ce:cross-ref refid="AFF3"><ce:sup>3</ce:sup></ce:cross-ref></ce:author><ce:author><ce:given-name>Marc R.</ce:given-name><ce:surname>Sontag</ce:surname><ce:degrees>Ph.D.</ce:degrees><ce:cross-ref refid="AFF1"><ce:sup>1</ce:sup></ce:cross-ref></ce:author><ce:author><ce:given-name>Marcia M.</ce:given-name><ce:surname>Urie</ce:surname><ce:degrees>Ph.D.</ce:degrees><ce:cross-ref refid="AFF4"><ce:sup>4</ce:sup></ce:cross-ref><ce:cross-ref refid="AFF5"><ce:sup>5</ce:sup></ce:cross-ref></ce:author><ce:author><ce:given-name>Robert E.</ce:given-name><ce:surname>Wallace</ce:surname><ce:degrees>Ph.D.</ce:degrees><ce:cross-ref refid="AFF1"><ce:sup>1</ce:sup></ce:cross-ref></ce:author><ce:author><ce:given-name>John W.</ce:given-name><ce:surname>Wong</ce:surname><ce:degrees>Ph.D.</ce:degrees><ce:cross-ref refid="AFF3"><ce:sup>3</ce:sup></ce:cross-ref></ce:author><ce:affiliation id="AFF1"><ce:label>a</ce:label><ce:textfn>University of Pennsylvania School of Medicine and the Fox Chase Cancer Center, Philadelphia, PA 19111, USA</ce:textfn></ce:affiliation><ce:affiliation id="AFF2"><ce:label>b</ce:label><ce:textfn>Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA</ce:textfn></ce:affiliation><ce:affiliation id="AFF3"><ce:label>c</ce:label><ce:textfn>Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO 63110, USA</ce:textfn></ce:affiliation><ce:affiliation id="AFF4"><ce:label>d</ce:label><ce:textfn>Massachusetts General Hospital, Dept. of Radiation Medicine, Boston, MA 02114, USA</ce:textfn></ce:affiliation><ce:affiliation id="AFF5"><ce:label>e</ce:label><ce:textfn>Harvard Medical School, USA</ce:textfn></ce:affiliation><ce:correspondence id="COR1"><ce:label>∗</ce:label><ce:text>Reprint requests to: Mary Ellen Masterson, Memorial Sloan-Kettering Cancer Center, Medical Physics, 1275 York Ave., New York, NY 10021.</ce:text></ce:correspondence></ce:author-group><ce:abstract><ce:section-title>Abstract</ce:section-title><ce:abstract-sec><ce:simple-para>Under the auspices of NCI contracts, four institutions have collaborated to assess the accuracy of the pixel-based dose calculation methods they employ for external photon treatment planning. The approach relied on comparing calculations using each group's algorithm with measurements in phantoms of increasing complexity. The first set of measurements consisted of ionization chamber measurements in water phantoms in normally incident square fields, an elongated field, a wedged field, a blocked field, and an obliquely incident beam. The second group of measurements was carried out using thermoluminescent dosimeters in phantoms designed to investigate the effects of surface curvature, high density heterogeneities, and low density heterogeneities. The final study tested the entire treatment planning system, including CT data conversion, in an anthropomorphic phantom. Overall, good agreement between calculation and measurements was found for all algorithms. Regions in which discrepancies were observed are pointed out, areas for algorithm improvement are identified and the clinical import of algorithm accuracy is discussed.</ce:simple-para></ce:abstract-sec></ce:abstract><ce:keywords><ce:section-title>Keywords</ce:section-title><ce:keyword><ce:text>External photon treatment planning</ce:text></ce:keyword><ce:keyword><ce:text>Dose calculations</ce:text></ce:keyword><ce:keyword><ce:text>Algorithm accuracy</ce:text></ce:keyword></ce:keywords></head></converted-article></istex:document></istex:metadataXml><mods version="3.6"><titleInfo><title>Interinstitutional experience in verification of external photon dose calculations</title></titleInfo><titleInfo type="alternative" contentType="CDATA"><title>Interinstitutional experience in verification of external photon dose calculations</title></titleInfo><name type="personal"><namePart type="given">Mary Ellen</namePart><namePart type="family">Masterson</namePart><namePart type="termsOfAddress">M.S.</namePart><affiliation>Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA</affiliation><description>Reprint requests to: Mary Ellen Masterson, Memorial Sloan-Kettering Cancer Center, Medical Physics, 1275 York Ave., New York, NY 10021.</description><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Glenn</namePart><namePart type="family">Barest</namePart><namePart type="termsOfAddress">B.S.</namePart><affiliation>Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Chen-Shou</namePart><namePart type="family">Chui</namePart><namePart type="termsOfAddress">Ph.D.</namePart><affiliation>Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Karen P.</namePart><namePart type="family">Doppke</namePart><namePart type="termsOfAddress">M.S.</namePart><affiliation>Massachusetts General Hospital, Dept. of Radiation Medicine, Boston, MA 02114, USA</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Robert D.</namePart><namePart type="family">Epperson</namePart><namePart type="termsOfAddress">B.A.</namePart><affiliation>University of Pennsylvania School of Medicine and the Fox Chase Cancer Center, Philadelphia, PA 19111, USA</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">William B.</namePart><namePart type="family">Harms</namePart><namePart type="termsOfAddress">B.S.</namePart><affiliation>Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO 63110, USA</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Kenneth E.</namePart><namePart type="family">Krippner</namePart><namePart type="termsOfAddress">M.S.</namePart><affiliation>University of Pennsylvania School of Medicine and the Fox Chase Cancer Center, Philadelphia, PA 19111, USAMemorial Sloan-Kettering Cancer Center, New York, NY 10021, USAMallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO 63110, USAMassachusetts General Hospital, Dept. of Radiation Medicine, Boston, MA 02114, USAHarvard Medical School, USA</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Radhe</namePart><namePart type="family">Mohan</namePart><namePart type="termsOfAddress">Ph.D.</namePart><affiliation>Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Eric D.</namePart><namePart type="family">Slessinger</namePart><namePart type="termsOfAddress">M.S.</namePart><affiliation>Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO 63110, USA</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Marc R.</namePart><namePart type="family">Sontag</namePart><namePart type="termsOfAddress">Ph.D.</namePart><affiliation>University of Pennsylvania School of Medicine and the Fox Chase Cancer Center, Philadelphia, PA 19111, USA</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Marcia M.</namePart><namePart type="family">Urie</namePart><namePart type="termsOfAddress">Ph.D.</namePart><affiliation>Massachusetts General Hospital, Dept. of Radiation Medicine, Boston, MA 02114, USA</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Robert E.</namePart><namePart type="family">Wallace</namePart><namePart type="termsOfAddress">Ph.D.</namePart><affiliation>University of Pennsylvania School of Medicine and the Fox Chase Cancer Center, Philadelphia, PA 19111, USA</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">John W.</namePart><namePart type="family">Wong</namePart><namePart type="termsOfAddress">Ph.D.</namePart><affiliation>Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO 63110, USA</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="research-article" displayLabel="Full-length article"></genre><originInfo><publisher>ELSEVIER</publisher><dateIssued encoding="w3cdtf">1991</dateIssued><copyrightDate encoding="w3cdtf">1991</copyrightDate></originInfo><language><languageTerm type="code" authority="iso639-2b">eng</languageTerm><languageTerm type="code" authority="rfc3066">en</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType></physicalDescription><abstract lang="en">Under the auspices of NCI contracts, four institutions have collaborated to assess the accuracy of the pixel-based dose calculation methods they employ for external photon treatment planning. The approach relied on comparing calculations using each group's algorithm with measurements in phantoms of increasing complexity. The first set of measurements consisted of ionization chamber measurements in water phantoms in normally incident square fields, an elongated field, a wedged field, a blocked field, and an obliquely incident beam. The second group of measurements was carried out using thermoluminescent dosimeters in phantoms designed to investigate the effects of surface curvature, high density heterogeneities, and low density heterogeneities. The final study tested the entire treatment planning system, including CT data conversion, in an anthropomorphic phantom. Overall, good agreement between calculation and measurements was found for all algorithms. Regions in which discrepancies were observed are pointed out, areas for algorithm improvement are identified and the clinical import of algorithm accuracy is discussed.</abstract><note>Supported in part by NCI Contracts N01 CM-47316, N01 CM-47695, N01 CM-47696, and N01 CM-47697.</note><note type="content">Section title: Original contribution</note><subject><genre>Keywords</genre><topic>External photon treatment planning</topic><topic>Dose calculations</topic><topic>Algorithm accuracy</topic></subject><relatedItem type="host"><titleInfo><title>International Journal of Radiation Oncology, Biology, Physics</title></titleInfo><titleInfo type="abbreviated"><title>ROB</title></titleInfo><genre type="Journal">journal</genre><originInfo><dateIssued encoding="w3cdtf">19910515</dateIssued></originInfo><identifier type="ISSN">0360-3016</identifier><identifier type="PII">S0360-3016(00)X0277-5</identifier><part><date>19910515</date><detail type="issue"><title>Three-Dimensional Photon Treatment Planning Report of the Collaborative Working Group on the Evaluation of Treatment Planning for External Photon Beam Radiotherapy</title></detail><detail type="volume"><number>21</number><caption>vol.</caption></detail><detail type="issue"><number>1</number><caption>no.</caption></detail><extent unit="issue pages"><start>1</start><end>265</end></extent><extent unit="pages"><start>37</start><end>58</end></extent></part></relatedItem><identifier type="istex">A665AE7F4DFAC2B71248C68444084AC1DCFD0C9D</identifier><identifier type="DOI">10.1016/0360-3016(91)90166-2</identifier><identifier type="PII">0360-3016(91)90166-2</identifier><recordInfo><recordContentSource>ELSEVIER</recordContentSource></recordInfo></mods></metadata><enrichments><istex:catWosTEI uri="https://api.istex.fr/document/A665AE7F4DFAC2B71248C68444084AC1DCFD0C9D/enrichments/catWos"><teiHeader><profileDesc><textClass><classCode scheme="WOS">ONCOLOGY</classCode><classCode scheme="WOS">RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING</classCode><classCode scheme="WOS">REHABILITATION</classCode></textClass></profileDesc></teiHeader></istex:catWosTEI></enrichments><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
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