Effects of an oral contraceptive containing chlormadinone acetate and ethinylestradiol on hair and skin quality in women wishing to use hormonal contraception.
Identifieur interne : 000C41 ( PubMed/Curation ); précédent : 000C40; suivant : 000C42Effects of an oral contraceptive containing chlormadinone acetate and ethinylestradiol on hair and skin quality in women wishing to use hormonal contraception.
Auteurs : M. Kerscher [Allemagne] ; T. Reuther ; N. Krueger ; H. BuntrockSource :
- Journal of the European Academy of Dermatology and Venereology : JEADV [ 1468-3083 ] ; 2013.
English descriptors
- KwdEn :
- MESH :
- chemical , administration & dosage : Chlormadinone Acetate, Ethinyl Estradiol.
- chemical , pharmacology : Contraceptives, Oral, Hormonal.
- drug effects : Hair, Skin.
- Female, Humans.
Abstract
Skin and hair appearance is important to body image. Oily skin and oily, impaired hair quality, which can develop in women taking certain types of hormonal contraceptives, may cause psychosocial stress.
DOI: 10.1111/j.1468-3083.2012.04497.x
PubMed: 22404700
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pubmed:22404700Le document en format XML
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<author><name sortKey="Kerscher, M" sort="Kerscher, M" uniqKey="Kerscher M" first="M" last="Kerscher">M. Kerscher</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Chemistry, Division of Cosmetic Sciences, University of Hamburg, Hamburg, Germany. martina.kerscher@uni-hamburg.de</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Chemistry, Division of Cosmetic Sciences, University of Hamburg, Hamburg</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Reuther, T" sort="Reuther, T" uniqKey="Reuther T" first="T" last="Reuther">T. Reuther</name>
</author>
<author><name sortKey="Krueger, N" sort="Krueger, N" uniqKey="Krueger N" first="N" last="Krueger">N. Krueger</name>
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<author><name sortKey="Buntrock, H" sort="Buntrock, H" uniqKey="Buntrock H" first="H" last="Buntrock">H. Buntrock</name>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">Effects of an oral contraceptive containing chlormadinone acetate and ethinylestradiol on hair and skin quality in women wishing to use hormonal contraception.</title>
<author><name sortKey="Kerscher, M" sort="Kerscher, M" uniqKey="Kerscher M" first="M" last="Kerscher">M. Kerscher</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Chemistry, Division of Cosmetic Sciences, University of Hamburg, Hamburg, Germany. martina.kerscher@uni-hamburg.de</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Chemistry, Division of Cosmetic Sciences, University of Hamburg, Hamburg</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Reuther, T" sort="Reuther, T" uniqKey="Reuther T" first="T" last="Reuther">T. Reuther</name>
</author>
<author><name sortKey="Krueger, N" sort="Krueger, N" uniqKey="Krueger N" first="N" last="Krueger">N. Krueger</name>
</author>
<author><name sortKey="Buntrock, H" sort="Buntrock, H" uniqKey="Buntrock H" first="H" last="Buntrock">H. Buntrock</name>
</author>
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<series><title level="j">Journal of the European Academy of Dermatology and Venereology : JEADV</title>
<idno type="eISSN">1468-3083</idno>
<imprint><date when="2013" type="published">2013</date>
</imprint>
</series>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Chlormadinone Acetate (administration & dosage)</term>
<term>Contraceptives, Oral, Hormonal (pharmacology)</term>
<term>Ethinyl Estradiol (administration & dosage)</term>
<term>Female</term>
<term>Hair (drug effects)</term>
<term>Humans</term>
<term>Skin (drug effects)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="administration & dosage" xml:lang="en"><term>Chlormadinone Acetate</term>
<term>Ethinyl Estradiol</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="pharmacology" xml:lang="en"><term>Contraceptives, Oral, Hormonal</term>
</keywords>
<keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Hair</term>
<term>Skin</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Female</term>
<term>Humans</term>
</keywords>
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<front><div type="abstract" xml:lang="en">Skin and hair appearance is important to body image. Oily skin and oily, impaired hair quality, which can develop in women taking certain types of hormonal contraceptives, may cause psychosocial stress.</div>
</front>
</TEI>
<pubmed><MedlineCitation Owner="NLM" Status="MEDLINE"><PMID Version="1">22404700</PMID>
<DateCreated><Year>2013</Year>
<Month>04</Month>
<Day>11</Day>
</DateCreated>
<DateCompleted><Year>2013</Year>
<Month>09</Month>
<Day>25</Day>
</DateCompleted>
<DateRevised><Year>2013</Year>
<Month>11</Month>
<Day>21</Day>
</DateRevised>
<Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1468-3083</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>27</Volume>
<Issue>5</Issue>
<PubDate><Year>2013</Year>
<Month>May</Month>
</PubDate>
</JournalIssue>
<Title>Journal of the European Academy of Dermatology and Venereology : JEADV</Title>
<ISOAbbreviation>J Eur Acad Dermatol Venereol</ISOAbbreviation>
</Journal>
<ArticleTitle>Effects of an oral contraceptive containing chlormadinone acetate and ethinylestradiol on hair and skin quality in women wishing to use hormonal contraception.</ArticleTitle>
<Pagination><MedlinePgn>601-8</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1111/j.1468-3083.2012.04497.x</ELocationID>
<Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Skin and hair appearance is important to body image. Oily skin and oily, impaired hair quality, which can develop in women taking certain types of hormonal contraceptives, may cause psychosocial stress.</AbstractText>
<AbstractText Label="OBJECTIVES" NlmCategory="OBJECTIVE">The aim of the current study was to investigate the effects of an oral monophasic contraceptive (0.03 mg ethinylestradiol/2 mg chlormadinone acetate) for 12 treatment cycles on the pathophysiology of oily skin and oily, impaired hair quality in healthy women.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">We assessed changes in hair and skin parameters at baseline, 12, 24 and 48 weeks, in 60 women aged 18-45 years. Psychological well-being was verified by two subject self-assessments (Hair quality, Hairdex).</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">Data from 31 subjects showed that treatment significantly improved sebum excretion at capillitium and forehead, and the number of terminal hairs. Visual haptic scores revealed significant decreases in capillitium seborrhoea, hair condition/density, capillitium dandruff and irritation/redness. Subject self-assessment confirmed improvements in hair quality. Treatment was well tolerated.</AbstractText>
<AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">Chlormadinone acetate in hormonal contraception provides excellent cosmetic and dermatological benefits, which can improve psychosocial well-being.</AbstractText>
<CopyrightInformation>© 2012 The Authors. Journal of the European Academy of Dermatology and Venereology © 2012 European Academy of Dermatology and Venereology.</CopyrightInformation>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Kerscher</LastName>
<ForeName>M</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Department of Chemistry, Division of Cosmetic Sciences, University of Hamburg, Hamburg, Germany. martina.kerscher@uni-hamburg.de</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Reuther</LastName>
<ForeName>T</ForeName>
<Initials>T</Initials>
</Author>
<Author ValidYN="Y"><LastName>Krueger</LastName>
<ForeName>N</ForeName>
<Initials>N</Initials>
</Author>
<Author ValidYN="Y"><LastName>Buntrock</LastName>
<ForeName>H</ForeName>
<Initials>H</Initials>
</Author>
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<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D017429">Clinical Trial, Phase IV</PublicationType>
<PublicationType UI="D016428">Journal Article</PublicationType>
<PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType>
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<ArticleDate DateType="Electronic"><Year>2012</Year>
<Month>03</Month>
<Day>10</Day>
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</Article>
<MedlineJournalInfo><Country>England</Country>
<MedlineTA>J Eur Acad Dermatol Venereol</MedlineTA>
<NlmUniqueID>9216037</NlmUniqueID>
<ISSNLinking>0926-9959</ISSNLinking>
</MedlineJournalInfo>
<ChemicalList><Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D003278">Contraceptives, Oral, Hormonal</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>0SY050L61N</RegistryNumber>
<NameOfSubstance UI="D002715">Chlormadinone Acetate</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>423D2T571U</RegistryNumber>
<NameOfSubstance UI="D004997">Ethinyl Estradiol</NameOfSubstance>
</Chemical>
</ChemicalList>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName MajorTopicYN="N" UI="D002715">Chlormadinone Acetate</DescriptorName>
<QualifierName MajorTopicYN="Y" UI="Q000008">administration & dosage</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D003278">Contraceptives, Oral, Hormonal</DescriptorName>
<QualifierName MajorTopicYN="Y" UI="Q000494">pharmacology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D004997">Ethinyl Estradiol</DescriptorName>
<QualifierName MajorTopicYN="Y" UI="Q000008">administration & dosage</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D005260">Female</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D006197">Hair</DescriptorName>
<QualifierName MajorTopicYN="Y" UI="Q000187">drug effects</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D006801">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D012867">Skin</DescriptorName>
<QualifierName MajorTopicYN="Y" UI="Q000187">drug effects</QualifierName>
</MeshHeading>
</MeshHeadingList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="aheadofprint"><Year>2012</Year>
<Month>3</Month>
<Day>10</Day>
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<PubMedPubDate PubStatus="medline"><Year>2013</Year>
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