Arterial Vasoreactivity is Equally Affected by In Vivo Cross-Clamping with Increasing Loads in Young and Middle-Aged Mice Aortas.
Identifieur interne : 000203 ( PubMed/Corpus ); précédent : 000202; suivant : 000204Arterial Vasoreactivity is Equally Affected by In Vivo Cross-Clamping with Increasing Loads in Young and Middle-Aged Mice Aortas.
Auteurs : Rachel Geenens ; Nele Famaey ; Andy Gijbels ; Valérie Verhulst ; Stefan Vinckier ; Jos Vander Sloten ; Paul HerijgersSource :
- Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia [ 2186-1005 ] ; 2016.
Abstract
To compensate for the lack of haptic feedback by surgical robots, limitation of exerted forces could be implemented. The limits should be based on the observed relationship between tissue load and induced damage. This study examines whether age-related changes influence this relationship.
DOI: 10.5761/atcs.oa.15-00225
PubMed: 26548538
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Arterial Vasoreactivity is Equally Affected by In Vivo Cross-Clamping with Increasing Loads in Young and Middle-Aged Mice Aortas.</title><author><name sortKey="Geenens, Rachel" sort="Geenens, Rachel" uniqKey="Geenens R" first="Rachel" last="Geenens">Rachel Geenens</name><affiliation><nlm:affiliation>Department of Cardiovascular Sciences, KU Leuven, Herestraat, Leuven, Belgium.</nlm:affiliation></affiliation></author><author><name sortKey="Famaey, Nele" sort="Famaey, Nele" uniqKey="Famaey N" first="Nele" last="Famaey">Nele Famaey</name></author><author><name sortKey="Gijbels, Andy" sort="Gijbels, Andy" uniqKey="Gijbels A" first="Andy" last="Gijbels">Andy Gijbels</name></author><author><name sortKey="Verhulst, Valerie" sort="Verhulst, Valerie" uniqKey="Verhulst V" first="Valérie" last="Verhulst">Valérie Verhulst</name></author><author><name sortKey="Vinckier, Stefan" sort="Vinckier, Stefan" uniqKey="Vinckier S" first="Stefan" last="Vinckier">Stefan Vinckier</name></author><author><name sortKey="Vander Sloten, Jos" sort="Vander Sloten, Jos" uniqKey="Vander Sloten J" first="Jos" last="Vander Sloten">Jos Vander Sloten</name></author><author><name sortKey="Herijgers, Paul" sort="Herijgers, Paul" uniqKey="Herijgers P" first="Paul" last="Herijgers">Paul Herijgers</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2016">2016</date><idno type="doi">10.5761/atcs.oa.15-00225</idno><idno type="RBID">pubmed:26548538</idno><idno type="pmid">26548538</idno><idno type="wicri:Area/PubMed/Corpus">000203</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Arterial Vasoreactivity is Equally Affected by In Vivo Cross-Clamping with Increasing Loads in Young and Middle-Aged Mice Aortas.</title><author><name sortKey="Geenens, Rachel" sort="Geenens, Rachel" uniqKey="Geenens R" first="Rachel" last="Geenens">Rachel Geenens</name><affiliation><nlm:affiliation>Department of Cardiovascular Sciences, KU Leuven, Herestraat, Leuven, Belgium.</nlm:affiliation></affiliation></author><author><name sortKey="Famaey, Nele" sort="Famaey, Nele" uniqKey="Famaey N" first="Nele" last="Famaey">Nele Famaey</name></author><author><name sortKey="Gijbels, Andy" sort="Gijbels, Andy" uniqKey="Gijbels A" first="Andy" last="Gijbels">Andy Gijbels</name></author><author><name sortKey="Verhulst, Valerie" sort="Verhulst, Valerie" uniqKey="Verhulst V" first="Valérie" last="Verhulst">Valérie Verhulst</name></author><author><name sortKey="Vinckier, Stefan" sort="Vinckier, Stefan" uniqKey="Vinckier S" first="Stefan" last="Vinckier">Stefan Vinckier</name></author><author><name sortKey="Vander Sloten, Jos" sort="Vander Sloten, Jos" uniqKey="Vander Sloten J" first="Jos" last="Vander Sloten">Jos Vander Sloten</name></author><author><name sortKey="Herijgers, Paul" sort="Herijgers, Paul" uniqKey="Herijgers P" first="Paul" last="Herijgers">Paul Herijgers</name></author></analytic><series><title level="j">Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia</title><idno type="eISSN">2186-1005</idno><imprint><date when="2016" type="published">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">To compensate for the lack of haptic feedback by surgical robots, limitation of exerted forces could be implemented. The limits should be based on the observed relationship between tissue load and induced damage. This study examines whether age-related changes influence this relationship.</div></front></TEI><pubmed><MedlineCitation Owner="NLM" Status="In-Data-Review"><PMID Version="1">26548538</PMID><DateCreated><Year>2016</Year><Month>02</Month><Day>23</Day></DateCreated><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">2186-1005</ISSN><JournalIssue CitedMedium="Internet"><Volume>22</Volume><Issue>1</Issue><PubDate><Year>2016</Year><Month>Feb</Month><Day>20</Day></PubDate></JournalIssue><Title>Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia</Title><ISOAbbreviation>Ann Thorac Cardiovasc Surg</ISOAbbreviation></Journal><ArticleTitle>Arterial Vasoreactivity is Equally Affected by In Vivo Cross-Clamping with Increasing Loads in Young and Middle-Aged Mice Aortas.</ArticleTitle><Pagination><MedlinePgn>38-43</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.5761/atcs.oa.15-00225</ELocationID><Abstract><AbstractText Label="PURPOSE" NlmCategory="OBJECTIVE">To compensate for the lack of haptic feedback by surgical robots, limitation of exerted forces could be implemented. The limits should be based on the observed relationship between tissue load and induced damage. This study examines whether age-related changes influence this relationship.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">Descending thoracic aortas of male C57BL/6J mice of 10, 25 and 40 weeks were clamped in vivo (no clamp, 0.5N or 2.0N) for 2 min. Functional integrity was tested in vitro by studying endothelium-dependent and -independent vasoreactivity.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">Endothelium-dependent relaxation deteriorated with increased clamping force at all ages. Clamping did not influence endothelium-independent vasodilation. Age (10, 25 and 40 weeks) did not significantly impact on the effect of clamping on endothelium-dependent and independent vasoreactivity.</AbstractText><AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">Within the tested conditions, mechanical clamping induces damage to the vascular endothelium, but not to the smooth muscle cells. Age has no effect on the obtained results in mice from 10 to 40 weeks old.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Geenens</LastName><ForeName>Rachel</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Department of Cardiovascular Sciences, KU Leuven, Herestraat, Leuven, Belgium.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Famaey</LastName><ForeName>Nele</ForeName><Initials>N</Initials></Author><Author ValidYN="Y"><LastName>Gijbels</LastName><ForeName>Andy</ForeName><Initials>A</Initials></Author><Author ValidYN="Y"><LastName>Verhulst</LastName><ForeName>Valérie</ForeName><Initials>V</Initials></Author><Author ValidYN="Y"><LastName>Vinckier</LastName><ForeName>Stefan</ForeName><Initials>S</Initials></Author><Author ValidYN="Y"><LastName>Vander Sloten</LastName><ForeName>Jos</ForeName><Initials>J</Initials></Author><Author ValidYN="Y"><LastName>Herijgers</LastName><ForeName>Paul</ForeName><Initials>P</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2015</Year><Month>11</Month><Day>06</Day></ArticleDate></Article><MedlineJournalInfo><Country>Japan</Country><MedlineTA>Ann Thorac Cardiovasc Surg</MedlineTA><NlmUniqueID>9703158</NlmUniqueID><ISSNLinking>1341-1098</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="aheadofprint"><Year>2015</Year><Month>11</Month><Day>06</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2015</Year><Month>11</Month><Day>10</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2015</Year><Month>11</Month><Day>10</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2015</Year><Month>11</Month><Day>10</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="doi">10.5761/atcs.oa.15-00225</ArticleId><ArticleId IdType="pubmed">26548538</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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