Management strategies for persistent epithelial defects of the cornea
Identifieur interne : 000C49 ( Pmc/Curation ); précédent : 000C48; suivant : 000C50Management strategies for persistent epithelial defects of the cornea
Auteurs : Lee R. Katzman ; Bennie H. JengSource :
- Saudi Journal of Ophthalmology [ 1319-4534 ] ; 2014.
Abstract
Management of patients with persistent epithelial defects of the cornea can be challenging to even the seasoned ophthalmologist. It is essential that one understands not only the pathophysiology of the failure of the epithelium to migrate and close a wound appropriately, but also the mechanism of action of the available treatment modalities at one’s disposal. This article serves as a review of current standard therapies, recently introduced alternative therapies gaining in popularity, and a look into the newest developments that may change the way we manage corneal surface disease.
Url:
DOI: 10.1016/j.sjopt.2014.06.011
PubMed: 25278792
PubMed Central: 4181455
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<author><name sortKey="Jeng, Bennie H" sort="Jeng, Bennie H" uniqKey="Jeng B" first="Bennie H." last="Jeng">Bennie H. Jeng</name>
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<front><div type="abstract" xml:lang="en"><p>Management of patients with persistent epithelial defects of the cornea can be challenging to even the seasoned ophthalmologist. It is essential that one understands not only the pathophysiology of the failure of the epithelium to migrate and close a wound appropriately, but also the mechanism of action of the available treatment modalities at one’s disposal. This article serves as a review of current standard therapies, recently introduced alternative therapies gaining in popularity, and a look into the newest developments that may change the way we manage corneal surface disease.</p>
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<pmc article-type="brief-report"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Saudi J Ophthalmol</journal-id>
<journal-id journal-id-type="iso-abbrev">Saudi J Ophthalmol</journal-id>
<journal-title-group><journal-title>Saudi Journal of Ophthalmology</journal-title>
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<issn pub-type="ppub">1319-4534</issn>
<publisher><publisher-name>Elsevier</publisher-name>
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<article-id pub-id-type="doi">10.1016/j.sjopt.2014.06.011</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Dry Eye and Ocular Surface Disease</subject>
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<title-group><article-title>Management strategies for persistent epithelial defects of the cornea</article-title>
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<contrib-group><contrib contrib-type="author"><name><surname>Katzman</surname>
<given-names>Lee R.</given-names>
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<degrees>MD</degrees>
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<contrib contrib-type="author"><name><surname>Jeng</surname>
<given-names>Bennie H.</given-names>
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<degrees>MD</degrees>
<email>bjeng@som.umaryland.edu</email>
<xref rid="cor1" ref-type="corresp">⁎</xref>
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<aff id="af005">Department of Ophthalmology and Visual Sciences, University of Maryland School of Medicine, Baltimore, MD, United States</aff>
<author-notes><corresp id="cor1"><label>⁎</label>
Corresponding author. Address: Department of Ophthalmology and Visual Sciences, University of Maryland School of Medicine, 419 W. Redwood Street, Suite 470, Baltimore, MD 21201, United States. Tel.: +1 (410) 328 5929; fax: +1 (410) 328 1178. <email>bjeng@som.umaryland.edu</email>
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<volume>28</volume>
<issue>3</issue>
<fpage>168</fpage>
<lpage>172</lpage>
<history><date date-type="received"><day>19</day>
<month>3</month>
<year>2014</year>
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<date date-type="rev-recd"><day>24</day>
<month>6</month>
<year>2014</year>
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<date date-type="accepted"><day>25</day>
<month>6</month>
<year>2014</year>
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<permissions><copyright-statement>© 2014 Production and hosting by Elsevier B.V. on behalf of King Saud University.</copyright-statement>
<copyright-year>2014</copyright-year>
<copyright-holder>Saudi Ophthalmological Society, King Saud University</copyright-holder>
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<abstract><p>Management of patients with persistent epithelial defects of the cornea can be challenging to even the seasoned ophthalmologist. It is essential that one understands not only the pathophysiology of the failure of the epithelium to migrate and close a wound appropriately, but also the mechanism of action of the available treatment modalities at one’s disposal. This article serves as a review of current standard therapies, recently introduced alternative therapies gaining in popularity, and a look into the newest developments that may change the way we manage corneal surface disease.</p>
</abstract>
<kwd-group><title>Keywords</title>
<kwd>Persistent epithelial defect</kwd>
<kwd>Non-healing epithelial defect</kwd>
<kwd>Autologous serum</kwd>
<kwd>Scleral contact lens</kwd>
<kwd>Amniotic membrane</kwd>
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