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Error induced by the estimation of the corneal power and the effective lens position with a rotationally asymmetric refractive multifocal intraocular lens

Identifieur interne : 000096 ( Pmc/Curation ); précédent : 000095; suivant : 000097

Error induced by the estimation of the corneal power and the effective lens position with a rotationally asymmetric refractive multifocal intraocular lens

Auteurs : David P. Pi Ero [Espagne] ; Vicente J. Camps [Espagne] ; María L. Ram N [Espagne] ; Ver Nica Mateo [Espagne] ; Rafael J. Pérez-Cambrodí [Espagne]

Source :

RBID : PMC:4458653

Abstract

AIM

To evaluate the prediction error in intraocular lens (IOL) power calculation for a rotationally asymmetric refractive multifocal IOL and the impact on this error of the optimization of the keratometric estimation of the corneal power and the prediction of the effective lens position (ELP).

METHODS

Retrospective study including a total of 25 eyes of 13 patients (age, 50 to 83y) with previous cataract surgery with implantation of the Lentis Mplus LS-312 IOL (Oculentis GmbH, Germany). In all cases, an adjusted IOL power (PIOLadj) was calculated based on Gaussian optics using a variable keratometric index value (nkadj) for the estimation of the corneal power (Pkadj) and on a new value for ELP (ELPadj) obtained by multiple regression analysis. This PIOLadj was compared with the IOL power implanted (PIOLReal) and the value proposed by three conventional formulas (Haigis, Hoffer Q and Holladay I).

RESULTS

PIOLReal was not significantly different than PIOLadj and Holladay IOL power (P>0.05). In the Bland and Altman analysis, PIOLadj showed lower mean difference (-0.07 D) and limits of agreement (of 1.47 and -1.61 D) when compared to PIOLReal than the IOL power value obtained with the Holladay formula. Furthermore, ELPadj was significantly lower than ELP calculated with other conventional formulas (P<0.01) and was found to be dependent on axial length, anterior chamber depth and Pkadj.

CONCLUSION

Refractive outcomes after cataract surgery with implantation of the multifocal IOL Lentis Mplus LS-312 can be optimized by minimizing the keratometric error and by estimating ELP using a mathematical expression dependent on anatomical factors.


Url:
DOI: 10.3980/j.issn.2222-3959.2015.03.12
PubMed: 26085998
PubMed Central: 4458653

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PMC:4458653

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<div type="abstract" xml:lang="en">
<sec>
<title>AIM</title>
<p>To evaluate the prediction error in intraocular lens (IOL) power calculation for a rotationally asymmetric refractive multifocal IOL and the impact on this error of the optimization of the keratometric estimation of the corneal power and the prediction of the effective lens position (ELP).</p>
</sec>
<sec>
<title>METHODS</title>
<p>Retrospective study including a total of 25 eyes of 13 patients (age, 50 to 83y) with previous cataract surgery with implantation of the Lentis Mplus LS-312 IOL (Oculentis GmbH, Germany). In all cases, an adjusted IOL power (P
<sub>IOLadj</sub>
) was calculated based on Gaussian optics using a variable keratometric index value (n
<sub>kadj</sub>
) for the estimation of the corneal power (P
<sub>kadj</sub>
) and on a new value for ELP (ELP
<sub>adj</sub>
) obtained by multiple regression analysis. This P
<sub>IOLadj</sub>
was compared with the IOL power implanted (P
<sub>IOLReal</sub>
) and the value proposed by three conventional formulas (Haigis, Hoffer Q and Holladay I).</p>
</sec>
<sec>
<title>RESULTS</title>
<p>P
<sub>IOLReal</sub>
was not significantly different than P
<sub>IOLadj</sub>
and Holladay IOL power (
<italic>P</italic>
>0.05). In the Bland and Altman analysis, P
<sub>IOLadj</sub>
showed lower mean difference (-0.07 D) and limits of agreement (of 1.47 and -1.61 D) when compared to P
<sub>IOLReal</sub>
than the IOL power value obtained with the Holladay formula. Furthermore, ELP
<sub>adj</sub>
was significantly lower than ELP calculated with other conventional formulas (
<italic>P</italic>
<0.01) and was found to be dependent on axial length, anterior chamber depth and P
<sub>kadj</sub>
.</p>
</sec>
<sec>
<title>CONCLUSION</title>
<p>Refractive outcomes after cataract surgery with implantation of the multifocal IOL Lentis Mplus LS-312 can be optimized by minimizing the keratometric error and by estimating ELP using a mathematical expression dependent on anatomical factors.</p>
</sec>
</div>
</front>
</TEI>
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<pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front>
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<journal-id journal-id-type="nlm-ta">Int J Ophthalmol</journal-id>
<journal-id journal-id-type="publisher-id">IJO</journal-id>
<journal-title-group>
<journal-title>International Journal of Ophthalmology</journal-title>
</journal-title-group>
<issn pub-type="ppub">2222-3959</issn>
<issn pub-type="epub">2227-4898</issn>
<publisher>
<publisher-name>International Journal of Ophthalmology Press</publisher-name>
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<article-id pub-id-type="pmc">4458653</article-id>
<article-id pub-id-type="publisher-id">ijo-08-03-501</article-id>
<article-id pub-id-type="doi">10.3980/j.issn.2222-3959.2015.03.12</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Clinical Research</subject>
</subj-group>
</article-categories>
<title-group>
<article-title>Error induced by the estimation of the corneal power and the effective lens position with a rotationally asymmetric refractive multifocal intraocular lens</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname>Piñero</surname>
<given-names>David P.</given-names>
</name>
<xref ref-type="aff" rid="aff1">1</xref>
<xref ref-type="aff" rid="aff2">2</xref>
<xref ref-type="aff" rid="aff3">3</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Camps</surname>
<given-names>Vicente J.</given-names>
</name>
<xref ref-type="aff" rid="aff1">1</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Ramón</surname>
<given-names>María L.</given-names>
</name>
<xref ref-type="aff" rid="aff2">2</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Mateo</surname>
<given-names>Verónica</given-names>
</name>
<xref ref-type="aff" rid="aff1">1</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Pérez-Cambrodí</surname>
<given-names>Rafael J.</given-names>
</name>
<xref ref-type="aff" rid="aff2">2</xref>
<xref ref-type="aff" rid="aff3">3</xref>
</contrib>
</contrib-group>
<aff id="aff1">
<label>1</label>
<addr-line>Grupo de Óptica y Percepción Visual (GOPV). Department of Optics, Pharmacology and Anatomy, University of Alicante, San Vicente del Raspeig, Alicante 03690, Spain</addr-line>
</aff>
<aff id="aff2">
<label>2</label>
<addr-line>Department of Ophthalmology (Oftalmar), Vithas Medimar International Hospital, Alicante 03016, Spain</addr-line>
</aff>
<aff id="aff3">
<label>3</label>
<addr-line>Foundation for the Visual Quality (FUNCAVIS: Fundación para la Calidad Visual), Alicante 03016, Spain</addr-line>
</aff>
<author-notes>
<corresp>
<bold>Correspondence to:</bold>
David P. Piñero. Department of Ophthalmology (OFTALMAR), 1
<sup>st</sup>
floor, Medimar International Hospital, C/Padre Arrupe 20, Alicante 03016, Spain.
<email>dpinero@oftalmar.es</email>
</corresp>
</author-notes>
<pub-date pub-type="epub">
<day>18</day>
<month>6</month>
<year>2015</year>
</pub-date>
<pub-date pub-type="collection">
<year>2015</year>
</pub-date>
<volume>8</volume>
<issue>3</issue>
<fpage>501</fpage>
<lpage>507</lpage>
<history>
<date date-type="received">
<day>2</day>
<month>9</month>
<year>2014</year>
</date>
<date date-type="accepted">
<day>1</day>
<month>12</month>
<year>2014</year>
</date>
</history>
<permissions>
<copyright-statement>International Journal of Ophthalmology Press</copyright-statement>
<copyright-year>2015</copyright-year>
</permissions>
<abstract>
<sec>
<title>AIM</title>
<p>To evaluate the prediction error in intraocular lens (IOL) power calculation for a rotationally asymmetric refractive multifocal IOL and the impact on this error of the optimization of the keratometric estimation of the corneal power and the prediction of the effective lens position (ELP).</p>
</sec>
<sec>
<title>METHODS</title>
<p>Retrospective study including a total of 25 eyes of 13 patients (age, 50 to 83y) with previous cataract surgery with implantation of the Lentis Mplus LS-312 IOL (Oculentis GmbH, Germany). In all cases, an adjusted IOL power (P
<sub>IOLadj</sub>
) was calculated based on Gaussian optics using a variable keratometric index value (n
<sub>kadj</sub>
) for the estimation of the corneal power (P
<sub>kadj</sub>
) and on a new value for ELP (ELP
<sub>adj</sub>
) obtained by multiple regression analysis. This P
<sub>IOLadj</sub>
was compared with the IOL power implanted (P
<sub>IOLReal</sub>
) and the value proposed by three conventional formulas (Haigis, Hoffer Q and Holladay I).</p>
</sec>
<sec>
<title>RESULTS</title>
<p>P
<sub>IOLReal</sub>
was not significantly different than P
<sub>IOLadj</sub>
and Holladay IOL power (
<italic>P</italic>
>0.05). In the Bland and Altman analysis, P
<sub>IOLadj</sub>
showed lower mean difference (-0.07 D) and limits of agreement (of 1.47 and -1.61 D) when compared to P
<sub>IOLReal</sub>
than the IOL power value obtained with the Holladay formula. Furthermore, ELP
<sub>adj</sub>
was significantly lower than ELP calculated with other conventional formulas (
<italic>P</italic>
<0.01) and was found to be dependent on axial length, anterior chamber depth and P
<sub>kadj</sub>
.</p>
</sec>
<sec>
<title>CONCLUSION</title>
<p>Refractive outcomes after cataract surgery with implantation of the multifocal IOL Lentis Mplus LS-312 can be optimized by minimizing the keratometric error and by estimating ELP using a mathematical expression dependent on anatomical factors.</p>
</sec>
</abstract>
<kwd-group>
<kwd>Mplus</kwd>
<kwd>multifocal intraocular lens</kwd>
<kwd>keratometry</kwd>
<kwd>effective lens position</kwd>
<kwd>intraocular lens power</kwd>
</kwd-group>
</article-meta>
</front>
</pmc>
</record>

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