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Complications, adverse events and additional intraocular surgery one year after cataract surgery in the Infant Aphakia Treatment Study

Identifieur interne : 001173 ( Pmc/Corpus ); précédent : 001172; suivant : 001174

Complications, adverse events and additional intraocular surgery one year after cataract surgery in the Infant Aphakia Treatment Study

Auteurs : David A. Plager ; Michael J. Lynn ; Edward G. Buckley ; M. Edward Wilson ; Scott R. Lambert

Source :

RBID : PMC:3230731

Abstract

Purpose

To compare rates and severity of complications between infants undergoing cataract surgery with and without intraocular lens (IOL) implant.

Design

Prospective randomized clinical trial.

Participants

The Infant Aphakia Treatment Study (IATS) is a randomized, multi-center (12) clinical trial comparing treatment of aphakia with a primary IOL or contact lens in 114 infants with unilateral congenital cataract.

Intervention

Infants underwent cataract surgery with or without placement of IOL.

Main Outcome Measures

The rate, character and severity of intraoperative complications (IC), adverse events (AE) and additional intraocular surgeries (AIS) during the first post operative year in the two groups were analyzed.

Results

There were more patients with ICs (28% vs. 11%, p=.031), AEs (77% vs 25%, p< .0001) and AIS (63% vs 12%, p< .0001) in the IOL group than the contact lens group. Iris prolapse was the most common intraoperative complication. The most common adverse event was visual axis opacification and the most common additional intraocular reoperation was a clearing of visual axis opacification.

Conclusion

The rates of intra operative complications, adverse events and additional intraocular surgeries one year postoperatively were numerically higher in the IOL group, but their functional impact does not clearly favor either treatment group.


Url:
DOI: 10.1016/j.ophtha.2011.06.017
PubMed: 21925737
PubMed Central: 3230731

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