Development and validation of an app-based cell counter for use in the clinical laboratory setting
Identifieur interne : 000E09 ( Pmc/Corpus ); précédent : 000E08; suivant : 000E10Development and validation of an app-based cell counter for use in the clinical laboratory setting
Auteurs : Alexander C. Thurman ; Jessica L. Davis ; Max Jan ; Charles E. Mcculloch ; Benjamin D. BuelowSource :
- Journal of Pathology Informatics [ 2229-5089 ] ; 2015.
Abstract
For decades cellular differentials have been generated exclusively on analog tabletop cell counters. With the advent of tablet computers, digital cell counters – in the form of mobile applications (“apps”) – now represent an alternative to analog devices. However, app-based counters have not been widely adopted by clinical laboratories, perhaps owing to a presumed decrease in count accuracy related to the lack of tactile feedback inherent in a touchscreen interface. We herein provide the first systematic evidence that digital cell counters function similarly to standard tabletop units.
We developed an app-based cell counter optimized for use in the clinical laboratory setting. Paired counts of 188 peripheral blood smears and 62 bone marrow aspirate smears were performed using our app-based counter and a standard analog device. Differences between paired data sets were analyzed using the correlation coefficient, Student's
All counts showed excellent agreement across all users and touch screen devices. With the exception of peripheral blood basophils (
Our analysis suggests that no systematic differences exist between cellular differentials obtained via app-based or tabletop counters and that agreement between these two methods is excellent.
Url:
DOI: 10.4103/2153-3539.150252
PubMed: 25722942
PubMed Central: 4338481
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