HapticV1, PascalFrancis, Corpus, bibRecord, 001352

Effect of in-the-bag intraocular lens fixation on the prevention of posterior capsule opacification

Identifieur interne : 001352 ( PascalFrancis/Corpus ); précédent : 001351; suivant : 001353

Effect of in-the-bag intraocular lens fixation on the prevention of posterior capsule opacification

Auteurs : Jagat Ram ; Suresh K. Pandey ; David J. Apple ; Liliana Werner ; Gagandeep S. Brar ; Ramandeep Singh ; Kulbhushan P. Chaudhary ; Amod Gupta

Source :

Journal of cataract and refractive surgery [ 0886-3350 ] ; 2001.

RBID : Pascal:01-0470941

Descripteurs français

Pascal (Inist)
- Cataracte, Technique, Traitement, Extraction, Cristallin, Extracapsulaire, Phacoémulsification, Etude comparative, Incidence, Opacification, Capsule, Postérieur, Prévention, Fixation, Biomatériau, Oeil, Homme.

English descriptors

KwdEn :
- Biomaterial, Capsule, Cataract, Comparative study, Extracapsular, Extraction, Eye, Fixation, Human, Incidence, Lens, Opacification, Phacoemulsification, Posterior, Prevention, Technique, Treatment.

Abstract

Purpose: To compare the incidence of posterior capsule opacification (PCO) after extracapsular cataract extraction (ECCE) and phacoemulsification and to evaluate the role of posterior chamber intraocular lens (PC IOL) haptic fixation and biomaterial/design in reducing the incidence. Setting: Postgraduate Institute of Medical Education and Research, Chandigarh, India; Center for Research on Ocular Therapeutics and Biodevices, Storm Eye Institute, Medical University of South Carolina, Charleston, South Carolina, USA. Methods: This study comprised 278 eyes of 263 patients having ECCE and 318 eyes of 297 patients having phacoemulsification with PC IOL implantation. Posterior capsule opacification leading to a decrease in Snellen visual acuity of 2 or more lines was considered visually significant. The presence of PCO and IOL haptic fixation were evaluated postoperatively using slitlamp biomicroscopy. Haptic position was noted as in-the-bag (B-B), 1 haptic in the bag and 1 in the sulcus (bag-sulcus [B-S]), or both haptics out of the bag (sulcus-sulcus [S-S]). In addition, the rate of visually significant PCO was compared among 3 IOL biomaterials: poly(methyl methacrylate), silicone, and hydrophobic acrylic. Results: Visually significant PCO occurred in 42.45% of eyes having ECCE and 19.18% of eyes having phacoemulsification (P <.001, chi-square test) after a mean follow-up of 2.4 years ± 0.7 (SD), In both groups, visually significant PCO was significantly less in eyes with B-B fixation than in those with B-S or S-S fixation (P <.001). The rate of visually significant PCO in all eyes in the phacoemulsification group with B-B fixation was low (11.90%) and was significantly lower in eyes with a hydrophobic acrylic IOL (2.22%; P <.05, chi-square test). Conclusions: In-the-bag PC IOL fixation is required to consistently reduce the incidence of PCO. Thorough removal of lens substance, including hydrodissection-assisted cortical cleanup, and in-the-bag PC IOL fixation seem to be the most important factors in reducing PCO, regardless of surgical procedure or IOL type used. Intraocular lens biomaterial and design also help prevent PCO.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

A01	`01`	`1`		`@0 0886-3350`
A02	`01`			`@0 JCSUEV`
A03		`1`		`@0 J. cataract refractive surg.`
A05				`@2 27`
A06				`@2 7`
A08	`01`	`1`	`ENG`	`@1 Effect of in-the-bag intraocular lens fixation on the prevention of posterior capsule opacification`
A11	`01`	`1`		`@1 RAM (Jagat)`
A11	`02`	`1`		`@1 PANDEY (Suresh K.)`
A11	`03`	`1`		`@1 APPLE (David J.)`
A11	`04`	`1`		`@1 WERNER (Liliana)`
A11	`05`	`1`		`@1 BRAR (Gagandeep S.)`
A11	`06`	`1`		`@1 SINGH (Ramandeep)`
A11	`07`	`1`		`@1 CHAUDHARY (Kulbhushan P.)`
A11	`08`	`1`		`@1 GUPTA (Amod)`
A14	`01`			`@1 Department of Ophthalmology, Postgraduate Institute of Medical Education and Research @2 Chandigarh @3 IND @Z 1 aut. @Z 5 aut. @Z 6 aut. @Z 8 aut.`
A14	`02`			`@1 The Center for Research on Ocular Therapeutics and Biodevices, Storm Eye Institute, Medical University of South Carolina @2 Charleston, South Carolina @3 USA @Z 2 aut. @Z 3 aut. @Z 4 aut.`
A14	`03`			`@1 Indira Gandbi Medical College Shimla @2 Shimla @3 IND @Z 7 aut.`
A20				`@1 1039-1046`
A21				`@1 2001`
A23	`01`			`@0 ENG`
A43	`01`			`@1 INIST @2 20937 @5 354000097139760110`
A44				`@0 0000 @1 © 2001 INIST-CNRS. All rights reserved.`
A45				`@0 31 ref.`
A47	`01`	`1`		`@0 01-0470941`
A60				`@1 P`
A61				`@0 A`
A64	`01`	`1`		`@0 Journal of cataract and refractive surgery`
A66	`01`			`@0 USA`
C01	`01`		`ENG`	@0 Purpose: To compare the incidence of posterior capsule opacification (PCO) after extracapsular cataract extraction (ECCE) and phacoemulsification and to evaluate the role of posterior chamber intraocular lens (PC IOL) haptic fixation and biomaterial/design in reducing the incidence. Setting: Postgraduate Institute of Medical Education and Research, Chandigarh, India; Center for Research on Ocular Therapeutics and Biodevices, Storm Eye Institute, Medical University of South Carolina, Charleston, South Carolina, USA. Methods: This study comprised 278 eyes of 263 patients having ECCE and 318 eyes of 297 patients having phacoemulsification with PC IOL implantation. Posterior capsule opacification leading to a decrease in Snellen visual acuity of 2 or more lines was considered visually significant. The presence of PCO and IOL haptic fixation were evaluated postoperatively using slitlamp biomicroscopy. Haptic position was noted as in-the-bag (B-B), 1 haptic in the bag and 1 in the sulcus (bag-sulcus [B-S]), or both haptics out of the bag (sulcus-sulcus [S-S]). In addition, the rate of visually significant PCO was compared among 3 IOL biomaterials: poly(methyl methacrylate), silicone, and hydrophobic acrylic. Results: Visually significant PCO occurred in 42.45% of eyes having ECCE and 19.18% of eyes having phacoemulsification (P <.001, chi-square test) after a mean follow-up of 2.4 years ± 0.7 (SD), In both groups, visually significant PCO was significantly less in eyes with B-B fixation than in those with B-S or S-S fixation (P <.001). The rate of visually significant PCO in all eyes in the phacoemulsification group with B-B fixation was low (11.90%) and was significantly lower in eyes with a hydrophobic acrylic IOL (2.22%; P <.05, chi-square test). Conclusions: In-the-bag PC IOL fixation is required to consistently reduce the incidence of PCO. Thorough removal of lens substance, including hydrodissection-assisted cortical cleanup, and in-the-bag PC IOL fixation seem to be the most important factors in reducing PCO, regardless of surgical procedure or IOL type used. Intraocular lens biomaterial and design also help prevent PCO.
C02	`01`	`X`		`@0 002B25B`
C03	`01`	`X`	`FRE`	`@0 Cataracte @5 01`
C03	`01`	`X`	`ENG`	`@0 Cataract @5 01`
C03	`01`	`X`	`SPA`	`@0 Catarata @5 01`
C03	`02`	`X`	`FRE`	`@0 Technique @5 02`
C03	`02`	`X`	`ENG`	`@0 Technique @5 02`
C03	`02`	`X`	`SPA`	`@0 Técnica @5 02`
C03	`03`	`X`	`FRE`	`@0 Traitement @5 03`
C03	`03`	`X`	`ENG`	`@0 Treatment @5 03`
C03	`03`	`X`	`SPA`	`@0 Tratamiento @5 03`
C03	`04`	`X`	`FRE`	`@0 Extraction @5 04`
C03	`04`	`X`	`ENG`	`@0 Extraction @5 04`
C03	`04`	`X`	`SPA`	`@0 Extracción @5 04`
C03	`05`	`X`	`FRE`	`@0 Cristallin @5 05`
C03	`05`	`X`	`ENG`	`@0 Lens @5 05`
C03	`05`	`X`	`SPA`	`@0 Cristalino @5 05`
C03	`06`	`X`	`FRE`	`@0 Extracapsulaire @5 06`
C03	`06`	`X`	`ENG`	`@0 Extracapsular @5 06`
C03	`06`	`X`	`SPA`	`@0 Extracapsular @5 06`
C03	`07`	`X`	`FRE`	`@0 Phacoémulsification @5 07`
C03	`07`	`X`	`ENG`	`@0 Phacoemulsification @5 07`
C03	`07`	`X`	`SPA`	`@0 Facoemulsificación @5 07`
C03	`08`	`X`	`FRE`	`@0 Etude comparative @5 08`
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C03	`08`	`X`	`SPA`	`@0 Estudio comparativo @5 08`
C03	`09`	`X`	`FRE`	`@0 Incidence @5 09`
C03	`09`	`X`	`ENG`	`@0 Incidence @5 09`
C03	`09`	`X`	`SPA`	`@0 Incidencia @5 09`
C03	`10`	`X`	`FRE`	`@0 Opacification @5 10`
C03	`10`	`X`	`ENG`	`@0 Opacification @5 10`
C03	`10`	`X`	`SPA`	`@0 Opacificación @5 10`
C03	`11`	`X`	`FRE`	`@0 Capsule @5 11`
C03	`11`	`X`	`ENG`	`@0 Capsule @5 11`
C03	`11`	`X`	`SPA`	`@0 Cápsula @5 11`
C03	`12`	`X`	`FRE`	`@0 Postérieur @5 12`
C03	`12`	`X`	`ENG`	`@0 Posterior @5 12`
C03	`12`	`X`	`SPA`	`@0 Posterior @5 12`
C03	`13`	`X`	`FRE`	`@0 Prévention @5 13`
C03	`13`	`X`	`ENG`	`@0 Prevention @5 13`
C03	`13`	`X`	`SPA`	`@0 Prevención @5 13`
C03	`14`	`X`	`FRE`	`@0 Fixation @5 17`
C03	`14`	`X`	`ENG`	`@0 Fixation @5 17`
C03	`14`	`X`	`SPA`	`@0 Fijación @5 17`
C03	`15`	`X`	`FRE`	`@0 Biomatériau @5 18`
C03	`15`	`X`	`ENG`	`@0 Biomaterial @5 18`
C03	`15`	`X`	`SPA`	`@0 Biomaterial @5 18`
C03	`16`	`X`	`FRE`	`@0 Oeil @5 19`
C03	`16`	`X`	`ENG`	`@0 Eye @5 19`
C03	`16`	`X`	`SPA`	`@0 Ojo @5 19`
C03	`17`	`X`	`FRE`	`@0 Homme @5 20`
C03	`17`	`X`	`ENG`	`@0 Human @5 20`
C03	`17`	`X`	`SPA`	`@0 Hombre @5 20`
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C07	`01`	`X`	`ENG`	`@0 Eye disease @5 37`
C07	`01`	`X`	`SPA`	`@0 Ojo patología @5 37`
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C07	`03`	`X`	`ENG`	`@0 Anterior segment disease @2 NM @5 39`
C07	`03`	`X`	`SPA`	`@0 Segmento anterior patología @2 NM @5 39`
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C07	`04`	`X`	`SPA`	`@0 Cirugía @5 45`
N21				`@1 337`

Format Inist (serveur)

NO :	PASCAL 01-0470941 INIST
ET :	Effect of in-the-bag intraocular lens fixation on the prevention of posterior capsule opacification
AU :	RAM (Jagat); PANDEY (Suresh K.); APPLE (David J.); WERNER (Liliana); BRAR (Gagandeep S.); SINGH (Ramandeep); CHAUDHARY (Kulbhushan P.); GUPTA (Amod)
AF :	Department of Ophthalmology, Postgraduate Institute of Medical Education and Research/Chandigarh/Inde (1 aut., 5 aut., 6 aut., 8 aut.); The Center for Research on Ocular Therapeutics and Biodevices, Storm Eye Institute, Medical University of South Carolina/Charleston, South Carolina/Etats-Unis (2 aut., 3 aut., 4 aut.); Indira Gandbi Medical College Shimla/Shimla/Inde (7 aut.)
DT :	Publication en série; Niveau analytique
SO :	Journal of cataract and refractive surgery; ISSN 0886-3350; Coden JCSUEV; Etats-Unis; Da. 2001; Vol. 27; No. 7; Pp. 1039-1046; Bibl. 31 ref.
LA :	Anglais
EA :	Purpose: To compare the incidence of posterior capsule opacification (PCO) after extracapsular cataract extraction (ECCE) and phacoemulsification and to evaluate the role of posterior chamber intraocular lens (PC IOL) haptic fixation and biomaterial/design in reducing the incidence. Setting: Postgraduate Institute of Medical Education and Research, Chandigarh, India; Center for Research on Ocular Therapeutics and Biodevices, Storm Eye Institute, Medical University of South Carolina, Charleston, South Carolina, USA. Methods: This study comprised 278 eyes of 263 patients having ECCE and 318 eyes of 297 patients having phacoemulsification with PC IOL implantation. Posterior capsule opacification leading to a decrease in Snellen visual acuity of 2 or more lines was considered visually significant. The presence of PCO and IOL haptic fixation were evaluated postoperatively using slitlamp biomicroscopy. Haptic position was noted as in-the-bag (B-B), 1 haptic in the bag and 1 in the sulcus (bag-sulcus [B-S]), or both haptics out of the bag (sulcus-sulcus [S-S]). In addition, the rate of visually significant PCO was compared among 3 IOL biomaterials: poly(methyl methacrylate), silicone, and hydrophobic acrylic. Results: Visually significant PCO occurred in 42.45% of eyes having ECCE and 19.18% of eyes having phacoemulsification (P <.001, chi-square test) after a mean follow-up of 2.4 years ± 0.7 (SD), In both groups, visually significant PCO was significantly less in eyes with B-B fixation than in those with B-S or S-S fixation (P <.001). The rate of visually significant PCO in all eyes in the phacoemulsification group with B-B fixation was low (11.90%) and was significantly lower in eyes with a hydrophobic acrylic IOL (2.22%; P <.05, chi-square test). Conclusions: In-the-bag PC IOL fixation is required to consistently reduce the incidence of PCO. Thorough removal of lens substance, including hydrodissection-assisted cortical cleanup, and in-the-bag PC IOL fixation seem to be the most important factors in reducing PCO, regardless of surgical procedure or IOL type used. Intraocular lens biomaterial and design also help prevent PCO.
CC :	002B25B
FD :	Cataracte; Technique; Traitement; Extraction; Cristallin; Extracapsulaire; Phacoémulsification; Etude comparative; Incidence; Opacification; Capsule; Postérieur; Prévention; Fixation; Biomatériau; Oeil; Homme
FG :	Oeil pathologie; Cristallin pathologie; Segment antérieur pathologie; Chirurgie
ED :	Cataract; Technique; Treatment; Extraction; Lens; Extracapsular; Phacoemulsification; Comparative study; Incidence; Opacification; Capsule; Posterior; Prevention; Fixation; Biomaterial; Eye; Human
EG :	Eye disease; Lens disease; Anterior segment disease; Surgery
SD :	Catarata; Técnica; Tratamiento; Extracción; Cristalino; Extracapsular; Facoemulsificación; Estudio comparativo; Incidencia; Opacificación; Cápsula; Posterior; Prevención; Fijación; Biomaterial; Ojo; Hombre
LO :	INIST-20937.354000097139760110
ID :	01-0470941

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Pascal:01-0470941

Le document en format XML

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<author><name sortKey="Brar, Gagandeep S" sort="Brar, Gagandeep S" uniqKey="Brar G" first="Gagandeep S." last="Brar">Gagandeep S. Brar</name>
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<author><name sortKey="Singh, Ramandeep" sort="Singh, Ramandeep" uniqKey="Singh R" first="Ramandeep" last="Singh">Ramandeep Singh</name>
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<author><name sortKey="Chaudhary, Kulbhushan P" sort="Chaudhary, Kulbhushan P" uniqKey="Chaudhary K" first="Kulbhushan P." last="Chaudhary">Kulbhushan P. Chaudhary</name>
<affiliation><inist:fA14 i1="03"><s1>Indira Gandbi Medical College Shimla</s1>
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<author><name sortKey="Gupta, Amod" sort="Gupta, Amod" uniqKey="Gupta A" first="Amod" last="Gupta">Amod Gupta</name>
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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Effect of in-the-bag intraocular lens fixation on the prevention of posterior capsule opacification</title>
<author><name sortKey="Ram, Jagat" sort="Ram, Jagat" uniqKey="Ram J" first="Jagat" last="Ram">Jagat Ram</name>
<affiliation><inist:fA14 i1="01"><s1>Department of Ophthalmology, Postgraduate Institute of Medical Education and Research</s1>
<s2>Chandigarh</s2>
<s3>IND</s3>
<sZ>1 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>8 aut.</sZ>
</inist:fA14>
</affiliation>
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<author><name sortKey="Pandey, Suresh K" sort="Pandey, Suresh K" uniqKey="Pandey S" first="Suresh K." last="Pandey">Suresh K. Pandey</name>
<affiliation><inist:fA14 i1="02"><s1>The Center for Research on Ocular Therapeutics and Biodevices, Storm Eye Institute, Medical University of South Carolina</s1>
<s2>Charleston, South Carolina</s2>
<s3>USA</s3>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Apple, David J" sort="Apple, David J" uniqKey="Apple D" first="David J." last="Apple">David J. Apple</name>
<affiliation><inist:fA14 i1="02"><s1>The Center for Research on Ocular Therapeutics and Biodevices, Storm Eye Institute, Medical University of South Carolina</s1>
<s2>Charleston, South Carolina</s2>
<s3>USA</s3>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Werner, Liliana" sort="Werner, Liliana" uniqKey="Werner L" first="Liliana" last="Werner">Liliana Werner</name>
<affiliation><inist:fA14 i1="02"><s1>The Center for Research on Ocular Therapeutics and Biodevices, Storm Eye Institute, Medical University of South Carolina</s1>
<s2>Charleston, South Carolina</s2>
<s3>USA</s3>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Brar, Gagandeep S" sort="Brar, Gagandeep S" uniqKey="Brar G" first="Gagandeep S." last="Brar">Gagandeep S. Brar</name>
<affiliation><inist:fA14 i1="01"><s1>Department of Ophthalmology, Postgraduate Institute of Medical Education and Research</s1>
<s2>Chandigarh</s2>
<s3>IND</s3>
<sZ>1 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>8 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Singh, Ramandeep" sort="Singh, Ramandeep" uniqKey="Singh R" first="Ramandeep" last="Singh">Ramandeep Singh</name>
<affiliation><inist:fA14 i1="01"><s1>Department of Ophthalmology, Postgraduate Institute of Medical Education and Research</s1>
<s2>Chandigarh</s2>
<s3>IND</s3>
<sZ>1 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>8 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Chaudhary, Kulbhushan P" sort="Chaudhary, Kulbhushan P" uniqKey="Chaudhary K" first="Kulbhushan P." last="Chaudhary">Kulbhushan P. Chaudhary</name>
<affiliation><inist:fA14 i1="03"><s1>Indira Gandbi Medical College Shimla</s1>
<s2>Shimla</s2>
<s3>IND</s3>
<sZ>7 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Gupta, Amod" sort="Gupta, Amod" uniqKey="Gupta A" first="Amod" last="Gupta">Amod Gupta</name>
<affiliation><inist:fA14 i1="01"><s1>Department of Ophthalmology, Postgraduate Institute of Medical Education and Research</s1>
<s2>Chandigarh</s2>
<s3>IND</s3>
<sZ>1 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>8 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
</analytic>
<series><title level="j" type="main">Journal of cataract and refractive surgery</title>
<title level="j" type="abbreviated">J. cataract refractive surg.</title>
<idno type="ISSN">0886-3350</idno>
<imprint><date when="2001">2001</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt><title level="j" type="main">Journal of cataract and refractive surgery</title>
<title level="j" type="abbreviated">J. cataract refractive surg.</title>
<idno type="ISSN">0886-3350</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Biomaterial</term>
<term>Capsule</term>
<term>Cataract</term>
<term>Comparative study</term>
<term>Extracapsular</term>
<term>Extraction</term>
<term>Eye</term>
<term>Fixation</term>
<term>Human</term>
<term>Incidence</term>
<term>Lens</term>
<term>Opacification</term>
<term>Phacoemulsification</term>
<term>Posterior</term>
<term>Prevention</term>
<term>Technique</term>
<term>Treatment</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Cataracte</term>
<term>Technique</term>
<term>Traitement</term>
<term>Extraction</term>
<term>Cristallin</term>
<term>Extracapsulaire</term>
<term>Phacoémulsification</term>
<term>Etude comparative</term>
<term>Incidence</term>
<term>Opacification</term>
<term>Capsule</term>
<term>Postérieur</term>
<term>Prévention</term>
<term>Fixation</term>
<term>Biomatériau</term>
<term>Oeil</term>
<term>Homme</term>
</keywords>
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<front><div type="abstract" xml:lang="en">Purpose: To compare the incidence of posterior capsule opacification (PCO) after extracapsular cataract extraction (ECCE) and phacoemulsification and to evaluate the role of posterior chamber intraocular lens (PC IOL) haptic fixation and biomaterial/design in reducing the incidence. Setting: Postgraduate Institute of Medical Education and Research, Chandigarh, India; Center for Research on Ocular Therapeutics and Biodevices, Storm Eye Institute, Medical University of South Carolina, Charleston, South Carolina, USA. Methods: This study comprised 278 eyes of 263 patients having ECCE and 318 eyes of 297 patients having phacoemulsification with PC IOL implantation. Posterior capsule opacification leading to a decrease in Snellen visual acuity of 2 or more lines was considered visually significant. The presence of PCO and IOL haptic fixation were evaluated postoperatively using slitlamp biomicroscopy. Haptic position was noted as in-the-bag (B-B), 1 haptic in the bag and 1 in the sulcus (bag-sulcus [B-S]), or both haptics out of the bag (sulcus-sulcus [S-S]). In addition, the rate of visually significant PCO was compared among 3 IOL biomaterials: poly(methyl methacrylate), silicone, and hydrophobic acrylic. Results: Visually significant PCO occurred in 42.45% of eyes having ECCE and 19.18% of eyes having phacoemulsification (P <.001, chi-square test) after a mean follow-up of 2.4 years ± 0.7 (SD), In both groups, visually significant PCO was significantly less in eyes with B-B fixation than in those with B-S or S-S fixation (P <.001). The rate of visually significant PCO in all eyes in the phacoemulsification group with B-B fixation was low (11.90%) and was significantly lower in eyes with a hydrophobic acrylic IOL (2.22%; P <.05, chi-square test). Conclusions: In-the-bag PC IOL fixation is required to consistently reduce the incidence of PCO. Thorough removal of lens substance, including hydrodissection-assisted cortical cleanup, and in-the-bag PC IOL fixation seem to be the most important factors in reducing PCO, regardless of surgical procedure or IOL type used. Intraocular lens biomaterial and design also help prevent PCO.</div>
</front>
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<fA08 i1="01" i2="1" l="ENG"><s1>Effect of in-the-bag intraocular lens fixation on the prevention of posterior capsule opacification</s1>
</fA08>
<fA11 i1="01" i2="1"><s1>RAM (Jagat)</s1>
</fA11>
<fA11 i1="02" i2="1"><s1>PANDEY (Suresh K.)</s1>
</fA11>
<fA11 i1="03" i2="1"><s1>APPLE (David J.)</s1>
</fA11>
<fA11 i1="04" i2="1"><s1>WERNER (Liliana)</s1>
</fA11>
<fA11 i1="05" i2="1"><s1>BRAR (Gagandeep S.)</s1>
</fA11>
<fA11 i1="06" i2="1"><s1>SINGH (Ramandeep)</s1>
</fA11>
<fA11 i1="07" i2="1"><s1>CHAUDHARY (Kulbhushan P.)</s1>
</fA11>
<fA11 i1="08" i2="1"><s1>GUPTA (Amod)</s1>
</fA11>
<fA14 i1="01"><s1>Department of Ophthalmology, Postgraduate Institute of Medical Education and Research</s1>
<s2>Chandigarh</s2>
<s3>IND</s3>
<sZ>1 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>8 aut.</sZ>
</fA14>
<fA14 i1="02"><s1>The Center for Research on Ocular Therapeutics and Biodevices, Storm Eye Institute, Medical University of South Carolina</s1>
<s2>Charleston, South Carolina</s2>
<s3>USA</s3>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
</fA14>
<fA14 i1="03"><s1>Indira Gandbi Medical College Shimla</s1>
<s2>Shimla</s2>
<s3>IND</s3>
<sZ>7 aut.</sZ>
</fA14>
<fA20><s1>1039-1046</s1>
</fA20>
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<fC01 i1="01" l="ENG"><s0>Purpose: To compare the incidence of posterior capsule opacification (PCO) after extracapsular cataract extraction (ECCE) and phacoemulsification and to evaluate the role of posterior chamber intraocular lens (PC IOL) haptic fixation and biomaterial/design in reducing the incidence. Setting: Postgraduate Institute of Medical Education and Research, Chandigarh, India; Center for Research on Ocular Therapeutics and Biodevices, Storm Eye Institute, Medical University of South Carolina, Charleston, South Carolina, USA. Methods: This study comprised 278 eyes of 263 patients having ECCE and 318 eyes of 297 patients having phacoemulsification with PC IOL implantation. Posterior capsule opacification leading to a decrease in Snellen visual acuity of 2 or more lines was considered visually significant. The presence of PCO and IOL haptic fixation were evaluated postoperatively using slitlamp biomicroscopy. Haptic position was noted as in-the-bag (B-B), 1 haptic in the bag and 1 in the sulcus (bag-sulcus [B-S]), or both haptics out of the bag (sulcus-sulcus [S-S]). In addition, the rate of visually significant PCO was compared among 3 IOL biomaterials: poly(methyl methacrylate), silicone, and hydrophobic acrylic. Results: Visually significant PCO occurred in 42.45% of eyes having ECCE and 19.18% of eyes having phacoemulsification (P <.001, chi-square test) after a mean follow-up of 2.4 years ± 0.7 (SD), In both groups, visually significant PCO was significantly less in eyes with B-B fixation than in those with B-S or S-S fixation (P <.001). The rate of visually significant PCO in all eyes in the phacoemulsification group with B-B fixation was low (11.90%) and was significantly lower in eyes with a hydrophobic acrylic IOL (2.22%; P <.05, chi-square test). Conclusions: In-the-bag PC IOL fixation is required to consistently reduce the incidence of PCO. Thorough removal of lens substance, including hydrodissection-assisted cortical cleanup, and in-the-bag PC IOL fixation seem to be the most important factors in reducing PCO, regardless of surgical procedure or IOL type used. Intraocular lens biomaterial and design also help prevent PCO.</s0>
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<fC02 i1="01" i2="X"><s0>002B25B</s0>
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<fC03 i1="01" i2="X" l="FRE"><s0>Cataracte</s0>
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<s5>04</s5>
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<s5>04</s5>
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<s5>05</s5>
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<s5>05</s5>
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<s5>06</s5>
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<s5>07</s5>
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<s5>07</s5>
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<s5>07</s5>
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<s5>08</s5>
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<s5>08</s5>
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<fC03 i1="08" i2="X" l="SPA"><s0>Estudio comparativo</s0>
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<fC03 i1="09" i2="X" l="FRE"><s0>Incidence</s0>
<s5>09</s5>
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<s5>09</s5>
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<s5>10</s5>
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<s5>11</s5>
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<s5>11</s5>
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<s5>12</s5>
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<s5>12</s5>
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<s5>13</s5>
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<s5>13</s5>
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<fC03 i1="13" i2="X" l="SPA"><s0>Prevención</s0>
<s5>13</s5>
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<fC03 i1="14" i2="X" l="FRE"><s0>Fixation</s0>
<s5>17</s5>
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<fC03 i1="14" i2="X" l="ENG"><s0>Fixation</s0>
<s5>17</s5>
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<fC03 i1="14" i2="X" l="SPA"><s0>Fijación</s0>
<s5>17</s5>
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<s5>38</s5>
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<s5>38</s5>
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<s5>39</s5>
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<server><NO>PASCAL 01-0470941 INIST</NO>
<ET>Effect of in-the-bag intraocular lens fixation on the prevention of posterior capsule opacification</ET>
<AU>RAM (Jagat); PANDEY (Suresh K.); APPLE (David J.); WERNER (Liliana); BRAR (Gagandeep S.); SINGH (Ramandeep); CHAUDHARY (Kulbhushan P.); GUPTA (Amod)</AU>
<AF>Department of Ophthalmology, Postgraduate Institute of Medical Education and Research/Chandigarh/Inde (1 aut., 5 aut., 6 aut., 8 aut.); The Center for Research on Ocular Therapeutics and Biodevices, Storm Eye Institute, Medical University of South Carolina/Charleston, South Carolina/Etats-Unis (2 aut., 3 aut., 4 aut.); Indira Gandbi Medical College Shimla/Shimla/Inde (7 aut.)</AF>
<DT>Publication en série; Niveau analytique</DT>
<SO>Journal of cataract and refractive surgery; ISSN 0886-3350; Coden JCSUEV; Etats-Unis; Da. 2001; Vol. 27; No. 7; Pp. 1039-1046; Bibl. 31 ref.</SO>
<LA>Anglais</LA>
<EA>Purpose: To compare the incidence of posterior capsule opacification (PCO) after extracapsular cataract extraction (ECCE) and phacoemulsification and to evaluate the role of posterior chamber intraocular lens (PC IOL) haptic fixation and biomaterial/design in reducing the incidence. Setting: Postgraduate Institute of Medical Education and Research, Chandigarh, India; Center for Research on Ocular Therapeutics and Biodevices, Storm Eye Institute, Medical University of South Carolina, Charleston, South Carolina, USA. Methods: This study comprised 278 eyes of 263 patients having ECCE and 318 eyes of 297 patients having phacoemulsification with PC IOL implantation. Posterior capsule opacification leading to a decrease in Snellen visual acuity of 2 or more lines was considered visually significant. The presence of PCO and IOL haptic fixation were evaluated postoperatively using slitlamp biomicroscopy. Haptic position was noted as in-the-bag (B-B), 1 haptic in the bag and 1 in the sulcus (bag-sulcus [B-S]), or both haptics out of the bag (sulcus-sulcus [S-S]). In addition, the rate of visually significant PCO was compared among 3 IOL biomaterials: poly(methyl methacrylate), silicone, and hydrophobic acrylic. Results: Visually significant PCO occurred in 42.45% of eyes having ECCE and 19.18% of eyes having phacoemulsification (P <.001, chi-square test) after a mean follow-up of 2.4 years ± 0.7 (SD), In both groups, visually significant PCO was significantly less in eyes with B-B fixation than in those with B-S or S-S fixation (P <.001). The rate of visually significant PCO in all eyes in the phacoemulsification group with B-B fixation was low (11.90%) and was significantly lower in eyes with a hydrophobic acrylic IOL (2.22%; P <.05, chi-square test). Conclusions: In-the-bag PC IOL fixation is required to consistently reduce the incidence of PCO. Thorough removal of lens substance, including hydrodissection-assisted cortical cleanup, and in-the-bag PC IOL fixation seem to be the most important factors in reducing PCO, regardless of surgical procedure or IOL type used. Intraocular lens biomaterial and design also help prevent PCO.</EA>
<CC>002B25B</CC>
<FD>Cataracte; Technique; Traitement; Extraction; Cristallin; Extracapsulaire; Phacoémulsification; Etude comparative; Incidence; Opacification; Capsule; Postérieur; Prévention; Fixation; Biomatériau; Oeil; Homme</FD>
<FG>Oeil pathologie; Cristallin pathologie; Segment antérieur pathologie; Chirurgie</FG>
<ED>Cataract; Technique; Treatment; Extraction; Lens; Extracapsular; Phacoemulsification; Comparative study; Incidence; Opacification; Capsule; Posterior; Prevention; Fixation; Biomaterial; Eye; Human</ED>
<EG>Eye disease; Lens disease; Anterior segment disease; Surgery</EG>
<SD>Catarata; Técnica; Tratamiento; Extracción; Cristalino; Extracapsular; Facoemulsificación; Estudio comparativo; Incidencia; Opacificación; Cápsula; Posterior; Prevención; Fijación; Biomaterial; Ojo; Hombre</SD>
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Effect of in-the-bag intraocular lens fixation on the prevention of posterior capsule opacification

Effect of in-the-bag intraocular lens fixation on the prevention of posterior capsule opacification

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