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Comparison of the biomechanical behavior of foldable intraocular lenses

Identifieur interne : 000F24 ( PascalFrancis/Corpus ); précédent : 000F23; suivant : 000F25

Comparison of the biomechanical behavior of foldable intraocular lenses

Auteurs : Stephen S. Lane ; Paula Burgi ; Gregory S. Milios ; Michael W. Orchowski ; Michael Vaughan ; Eric Schwarte

Source :

RBID : Pascal:05-0000426

Descripteurs français

English descriptors

Abstract

Purpose: To compare a standardized battery of biomechanical laboratory tests to assess the performance of popular foldable intraocular lenses (lOLs). Setting: Biomedical testing facilities, Alcon Research, Ltd., Fort Worth, Texas, USA. Methods: Using industry-standard biomechanical testing techniques, 1- and 3-piece foldable lOLs (Alcon AcrySof® MA60BM, MA30BA, SA30AL, SA60AT; Allergan Sensar® AR40, PhacoFlex® II SI-40NB; Bausch & Lomb Soflex® LI61U; Pharmacia & Upjohn CeeOn® 920) and a 1-piece all-poly(methyl methacrylate) (PMMA) IOL (Alcon MZ30BD) were tested under identical conditions with regard to (1) tensile/elastic properties by comparing haptic pull strength and haptic elongation and (2) compression properties by comparing haptic compression forces, haptic compression force decay over time, and axial displacement. All tests were performed with the IOLs submersed in a controlled-temperature water bath (mean 35°C ± 2°C [SD]). Results: For all lOLs, the ultimate elongation and pull strength of the haptics before failure was highest with the Alcon SA30AL and SA60AT. Similarly, the force required to compress haptics to a prescribed 10.0 mm diameter was least with the SA30AL and the SA60AT lenses. These 1-piece lenses also showed the least decay of residual compression force as a function of time. Optic displacement along the optical axis with haptic compression to 10.0 mm was least with the Alcon 1-piece lOLs and the all-PMMA control IOL. Conclusion: AcrySof 1-piece SA30AL and SA60AT lOLs demonstrated superior biomechanical characteristics over other foldable IOL desians.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

pA  
A01 01  1    @0 0886-3350
A02 01      @0 JCSUEV
A03   1    @0 J. cataract refractive surg.
A05       @2 30
A06       @2 11
A08 01  1  ENG  @1 Comparison of the biomechanical behavior of foldable intraocular lenses
A11 01  1    @1 LANE (Stephen S.)
A11 02  1    @1 BURGI (Paula)
A11 03  1    @1 MILIOS (Gregory S.)
A11 04  1    @1 ORCHOWSKI (Michael W.)
A11 05  1    @1 VAUGHAN (Michael)
A11 06  1    @1 SCHWARTE (Eric)
A14 01      @1 Alcon Research, Ltd. @2 Fort Worth, Texas @3 USA @Z 1 aut. @Z 2 aut. @Z 3 aut. @Z 4 aut. @Z 5 aut. @Z 6 aut.
A20       @1 2397-2402
A21       @1 2004
A23 01      @0 ENG
A43 01      @1 INIST @2 20937 @5 354000122632170240
A44       @0 0000 @1 © 2005 INIST-CNRS. All rights reserved.
A45       @0 5 ref.
A47 01  1    @0 05-0000426
A60       @1 P
A61       @0 A
A64 01  1    @0 Journal of cataract and refractive surgery
A66 01      @0 USA
C01 01    ENG  @0 Purpose: To compare a standardized battery of biomechanical laboratory tests to assess the performance of popular foldable intraocular lenses (lOLs). Setting: Biomedical testing facilities, Alcon Research, Ltd., Fort Worth, Texas, USA. Methods: Using industry-standard biomechanical testing techniques, 1- and 3-piece foldable lOLs (Alcon AcrySof® MA60BM, MA30BA, SA30AL, SA60AT; Allergan Sensar® AR40, PhacoFlex® II SI-40NB; Bausch & Lomb Soflex® LI61U; Pharmacia & Upjohn CeeOn® 920) and a 1-piece all-poly(methyl methacrylate) (PMMA) IOL (Alcon MZ30BD) were tested under identical conditions with regard to (1) tensile/elastic properties by comparing haptic pull strength and haptic elongation and (2) compression properties by comparing haptic compression forces, haptic compression force decay over time, and axial displacement. All tests were performed with the IOLs submersed in a controlled-temperature water bath (mean 35°C ± 2°C [SD]). Results: For all lOLs, the ultimate elongation and pull strength of the haptics before failure was highest with the Alcon SA30AL and SA60AT. Similarly, the force required to compress haptics to a prescribed 10.0 mm diameter was least with the SA30AL and the SA60AT lenses. These 1-piece lenses also showed the least decay of residual compression force as a function of time. Optic displacement along the optical axis with haptic compression to 10.0 mm was least with the Alcon 1-piece lOLs and the all-PMMA control IOL. Conclusion: AcrySof 1-piece SA30AL and SA60AT lOLs demonstrated superior biomechanical characteristics over other foldable IOL desians.
C02 01  X    @0 002B25B
C02 02  X    @0 002B26B
C03 01  X  FRE  @0 Etude comparative @5 02
C03 01  X  ENG  @0 Comparative study @5 02
C03 01  X  SPA  @0 Estudio comparativo @5 02
C03 02  X  FRE  @0 Comportement @5 03
C03 02  X  ENG  @0 Behavior @5 03
C03 02  X  SPA  @0 Conducta @5 03
C03 03  X  FRE  @0 Lentille intraoculaire @5 05
C03 03  X  ENG  @0 Intraocular lens @5 05
C03 03  X  SPA  @0 Lente intraocular @5 05
C03 04  X  FRE  @0 Chirurgie @5 06
C03 04  X  ENG  @0 Surgery @5 06
C03 04  X  SPA  @0 Cirugía @5 06
C03 05  X  FRE  @0 Ophtalmologie @5 08
C03 05  X  ENG  @0 Ophthalmology @5 08
C03 05  X  SPA  @0 Oftalmología @5 08
C03 06  X  FRE  @0 Traitement @5 25
C03 06  X  ENG  @0 Treatment @5 25
C03 06  X  SPA  @0 Tratamiento @5 25
N21       @1 004
N44 01      @1 OTO
N82       @1 OTO

Format Inist (serveur)

NO : PASCAL 05-0000426 INIST
ET : Comparison of the biomechanical behavior of foldable intraocular lenses
AU : LANE (Stephen S.); BURGI (Paula); MILIOS (Gregory S.); ORCHOWSKI (Michael W.); VAUGHAN (Michael); SCHWARTE (Eric)
AF : Alcon Research, Ltd./Fort Worth, Texas/Etats-Unis (1 aut., 2 aut., 3 aut., 4 aut., 5 aut., 6 aut.)
DT : Publication en série; Niveau analytique
SO : Journal of cataract and refractive surgery; ISSN 0886-3350; Coden JCSUEV; Etats-Unis; Da. 2004; Vol. 30; No. 11; Pp. 2397-2402; Bibl. 5 ref.
LA : Anglais
EA : Purpose: To compare a standardized battery of biomechanical laboratory tests to assess the performance of popular foldable intraocular lenses (lOLs). Setting: Biomedical testing facilities, Alcon Research, Ltd., Fort Worth, Texas, USA. Methods: Using industry-standard biomechanical testing techniques, 1- and 3-piece foldable lOLs (Alcon AcrySof® MA60BM, MA30BA, SA30AL, SA60AT; Allergan Sensar® AR40, PhacoFlex® II SI-40NB; Bausch & Lomb Soflex® LI61U; Pharmacia & Upjohn CeeOn® 920) and a 1-piece all-poly(methyl methacrylate) (PMMA) IOL (Alcon MZ30BD) were tested under identical conditions with regard to (1) tensile/elastic properties by comparing haptic pull strength and haptic elongation and (2) compression properties by comparing haptic compression forces, haptic compression force decay over time, and axial displacement. All tests were performed with the IOLs submersed in a controlled-temperature water bath (mean 35°C ± 2°C [SD]). Results: For all lOLs, the ultimate elongation and pull strength of the haptics before failure was highest with the Alcon SA30AL and SA60AT. Similarly, the force required to compress haptics to a prescribed 10.0 mm diameter was least with the SA30AL and the SA60AT lenses. These 1-piece lenses also showed the least decay of residual compression force as a function of time. Optic displacement along the optical axis with haptic compression to 10.0 mm was least with the Alcon 1-piece lOLs and the all-PMMA control IOL. Conclusion: AcrySof 1-piece SA30AL and SA60AT lOLs demonstrated superior biomechanical characteristics over other foldable IOL desians.
CC : 002B25B; 002B26B
FD : Etude comparative; Comportement; Lentille intraoculaire; Chirurgie; Ophtalmologie; Traitement
ED : Comparative study; Behavior; Intraocular lens; Surgery; Ophthalmology; Treatment
SD : Estudio comparativo; Conducta; Lente intraocular; Cirugía; Oftalmología; Tratamiento
LO : INIST-20937.354000122632170240
ID : 05-0000426

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Pascal:05-0000426

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<div type="abstract" xml:lang="en">Purpose: To compare a standardized battery of biomechanical laboratory tests to assess the performance of popular foldable intraocular lenses (lOLs). Setting: Biomedical testing facilities, Alcon Research, Ltd., Fort Worth, Texas, USA. Methods: Using industry-standard biomechanical testing techniques, 1- and 3-piece foldable lOLs (Alcon AcrySof® MA60BM, MA30BA, SA30AL, SA60AT; Allergan Sensar® AR40, PhacoFlex® II SI-40NB; Bausch & Lomb Soflex® LI61U; Pharmacia & Upjohn CeeOn® 920) and a 1-piece all-poly(methyl methacrylate) (PMMA) IOL (Alcon MZ30BD) were tested under identical conditions with regard to (1) tensile/elastic properties by comparing haptic pull strength and haptic elongation and (2) compression properties by comparing haptic compression forces, haptic compression force decay over time, and axial displacement. All tests were performed with the IOLs submersed in a controlled-temperature water bath (mean 35°C ± 2°C [SD]). Results: For all lOLs, the ultimate elongation and pull strength of the haptics before failure was highest with the Alcon SA30AL and SA60AT. Similarly, the force required to compress haptics to a prescribed 10.0 mm diameter was least with the SA30AL and the SA60AT lenses. These 1-piece lenses also showed the least decay of residual compression force as a function of time. Optic displacement along the optical axis with haptic compression to 10.0 mm was least with the Alcon 1-piece lOLs and the all-PMMA control IOL. Conclusion: AcrySof 1-piece SA30AL and SA60AT lOLs demonstrated superior biomechanical characteristics over other foldable IOL desians.</div>
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<s0>Purpose: To compare a standardized battery of biomechanical laboratory tests to assess the performance of popular foldable intraocular lenses (lOLs). Setting: Biomedical testing facilities, Alcon Research, Ltd., Fort Worth, Texas, USA. Methods: Using industry-standard biomechanical testing techniques, 1- and 3-piece foldable lOLs (Alcon AcrySof® MA60BM, MA30BA, SA30AL, SA60AT; Allergan Sensar® AR40, PhacoFlex® II SI-40NB; Bausch & Lomb Soflex® LI61U; Pharmacia & Upjohn CeeOn® 920) and a 1-piece all-poly(methyl methacrylate) (PMMA) IOL (Alcon MZ30BD) were tested under identical conditions with regard to (1) tensile/elastic properties by comparing haptic pull strength and haptic elongation and (2) compression properties by comparing haptic compression forces, haptic compression force decay over time, and axial displacement. All tests were performed with the IOLs submersed in a controlled-temperature water bath (mean 35°C ± 2°C [SD]). Results: For all lOLs, the ultimate elongation and pull strength of the haptics before failure was highest with the Alcon SA30AL and SA60AT. Similarly, the force required to compress haptics to a prescribed 10.0 mm diameter was least with the SA30AL and the SA60AT lenses. These 1-piece lenses also showed the least decay of residual compression force as a function of time. Optic displacement along the optical axis with haptic compression to 10.0 mm was least with the Alcon 1-piece lOLs and the all-PMMA control IOL. Conclusion: AcrySof 1-piece SA30AL and SA60AT lOLs demonstrated superior biomechanical characteristics over other foldable IOL desians.</s0>
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<NO>PASCAL 05-0000426 INIST</NO>
<ET>Comparison of the biomechanical behavior of foldable intraocular lenses</ET>
<AU>LANE (Stephen S.); BURGI (Paula); MILIOS (Gregory S.); ORCHOWSKI (Michael W.); VAUGHAN (Michael); SCHWARTE (Eric)</AU>
<AF>Alcon Research, Ltd./Fort Worth, Texas/Etats-Unis (1 aut., 2 aut., 3 aut., 4 aut., 5 aut., 6 aut.)</AF>
<DT>Publication en série; Niveau analytique</DT>
<SO>Journal of cataract and refractive surgery; ISSN 0886-3350; Coden JCSUEV; Etats-Unis; Da. 2004; Vol. 30; No. 11; Pp. 2397-2402; Bibl. 5 ref.</SO>
<LA>Anglais</LA>
<EA>Purpose: To compare a standardized battery of biomechanical laboratory tests to assess the performance of popular foldable intraocular lenses (lOLs). Setting: Biomedical testing facilities, Alcon Research, Ltd., Fort Worth, Texas, USA. Methods: Using industry-standard biomechanical testing techniques, 1- and 3-piece foldable lOLs (Alcon AcrySof® MA60BM, MA30BA, SA30AL, SA60AT; Allergan Sensar® AR40, PhacoFlex® II SI-40NB; Bausch & Lomb Soflex® LI61U; Pharmacia & Upjohn CeeOn® 920) and a 1-piece all-poly(methyl methacrylate) (PMMA) IOL (Alcon MZ30BD) were tested under identical conditions with regard to (1) tensile/elastic properties by comparing haptic pull strength and haptic elongation and (2) compression properties by comparing haptic compression forces, haptic compression force decay over time, and axial displacement. All tests were performed with the IOLs submersed in a controlled-temperature water bath (mean 35°C ± 2°C [SD]). Results: For all lOLs, the ultimate elongation and pull strength of the haptics before failure was highest with the Alcon SA30AL and SA60AT. Similarly, the force required to compress haptics to a prescribed 10.0 mm diameter was least with the SA30AL and the SA60AT lenses. These 1-piece lenses also showed the least decay of residual compression force as a function of time. Optic displacement along the optical axis with haptic compression to 10.0 mm was least with the Alcon 1-piece lOLs and the all-PMMA control IOL. Conclusion: AcrySof 1-piece SA30AL and SA60AT lOLs demonstrated superior biomechanical characteristics over other foldable IOL desians.</EA>
<CC>002B25B; 002B26B</CC>
<FD>Etude comparative; Comportement; Lentille intraoculaire; Chirurgie; Ophtalmologie; Traitement</FD>
<ED>Comparative study; Behavior; Intraocular lens; Surgery; Ophthalmology; Treatment</ED>
<SD>Estudio comparativo; Conducta; Lente intraocular; Cirugía; Oftalmología; Tratamiento</SD>
<LO>INIST-20937.354000122632170240</LO>
<ID>05-0000426</ID>
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