Comparison of posterior capsule opacification between the 1-piece and 3-piece Acrysof intraocular lenses: Two-year results of a randomized trial
Identifieur interne : 000F08 ( PascalFrancis/Corpus ); précédent : 000F07; suivant : 000F09Comparison of posterior capsule opacification between the 1-piece and 3-piece Acrysof intraocular lenses: Two-year results of a randomized trial
Auteurs : Stefan Sacu ; Oliver Findl ; Rupert Menapace ; Wolf Buehl ; Mathias WirtitschSource :
- Ophthalmology : (Rochester, MN) [ 0161-6420 ] ; 2004.
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- Pascal (Inist)
English descriptors
- KwdEn :
Abstract
Purpose: To compare intensity of posterior capsule opacification (PCO) between the 1-piece and 3-piece haptic designs of an open-loop hydrophobic acrylic intraocular lens (IOL). Design: A randomized, patient- and examiner-masked clinical trial with intraindividual comparison. Participants: Fifty-two patients with bilateral age-related cataract (104 eyes). Methods: Each patient had cataract surgery in both eyes and received a 1-piece Acrysof IOL in one eye and a 3-piece Acrysof IOL in the fellow eye. Follow-up examinations were at 1 week, 1 month, 6 months, 1 year, and 2 years. Patients were examined at the slit lamp, visual acuity (VA) was determined, and standardized high-resolution digital retroillumination images of the posterior capsule were taken. The intensity of PCO was assessed subjectively at the slit lamp and objectively using automated image analysis software. Main Outcome Measure: Posterior capsule opacification score (scale, 0-10). Results: There was no significant difference between IOL styles in best-corrected VA, rhexis/IOL overlap, capsular folds, and amount of anterior capsule opacification during the follow-up period. One year postoperatively, the amount of regeneratory PCO was higher for the 1-piece Acrysof eyes (image analysis software score: 1.3) than for the 3-piece Acrysof eyes (score: 0.9; P = 0.002). However, 2 years postoperatively, there was no significant difference between the 2 IOL styles (1-piece: 1.5; 3-piece: 1.3; P = 0.3). Neodymium:yttrium-aluminum-garnet capsulotomy was not performed in the study. Conclusion: One year postoperatively, the 1 -piece Acrysof showed slightly more regeneratory PCO than the 3-piece Acrysof. However, 2 years postoperatively, the barrier effect of the 1-piece design was comparable to that of the 3-piece haptic design, with low PCO intensity.
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NO : | PASCAL 05-0067783 INIST |
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ET : | Comparison of posterior capsule opacification between the 1-piece and 3-piece Acrysof intraocular lenses: Two-year results of a randomized trial |
AU : | SACU (Stefan); FINDL (Oliver); MENAPACE (Rupert); BUEHL (Wolf); WIRTITSCH (Mathias) |
AF : | Department of Ophthalmology, Medical University Vienna/Vienna/Autriche (1 aut., 2 aut., 3 aut., 4 aut., 5 aut.) |
DT : | Publication en série; Niveau analytique |
SO : | Ophthalmology : (Rochester, MN); ISSN 0161-6420; Coden OPHTDG; Etats-Unis; Da. 2004; Vol. 111; No. 10; Pp. 1840-1846; Bibl. 29 ref. |
LA : | Anglais |
EA : | Purpose: To compare intensity of posterior capsule opacification (PCO) between the 1-piece and 3-piece haptic designs of an open-loop hydrophobic acrylic intraocular lens (IOL). Design: A randomized, patient- and examiner-masked clinical trial with intraindividual comparison. Participants: Fifty-two patients with bilateral age-related cataract (104 eyes). Methods: Each patient had cataract surgery in both eyes and received a 1-piece Acrysof IOL in one eye and a 3-piece Acrysof IOL in the fellow eye. Follow-up examinations were at 1 week, 1 month, 6 months, 1 year, and 2 years. Patients were examined at the slit lamp, visual acuity (VA) was determined, and standardized high-resolution digital retroillumination images of the posterior capsule were taken. The intensity of PCO was assessed subjectively at the slit lamp and objectively using automated image analysis software. Main Outcome Measure: Posterior capsule opacification score (scale, 0-10). Results: There was no significant difference between IOL styles in best-corrected VA, rhexis/IOL overlap, capsular folds, and amount of anterior capsule opacification during the follow-up period. One year postoperatively, the amount of regeneratory PCO was higher for the 1-piece Acrysof eyes (image analysis software score: 1.3) than for the 3-piece Acrysof eyes (score: 0.9; P = 0.002). However, 2 years postoperatively, there was no significant difference between the 2 IOL styles (1-piece: 1.5; 3-piece: 1.3; P = 0.3). Neodymium:yttrium-aluminum-garnet capsulotomy was not performed in the study. Conclusion: One year postoperatively, the 1 -piece Acrysof showed slightly more regeneratory PCO than the 3-piece Acrysof. However, 2 years postoperatively, the barrier effect of the 1-piece design was comparable to that of the 3-piece haptic design, with low PCO intensity. |
CC : | 002B25B |
FD : | Etude comparative; Postérieur; Capsule; Gélule; Opacification; Lentille intraoculaire; Randomisation; Ophtalmologie; Traitement |
FG : | Chirurgie |
ED : | Comparative study; Posterior; Capsule; Hard capsule; Opacification; Intraocular lens; Randomization; Ophthalmology; Treatment |
EG : | Surgery |
SD : | Estudio comparativo; Posterior; Cápsula; Cápsula dura; Opacificación; Lente intraocular; Aleatorización; Oftalmología; Tratamiento |
LO : | INIST-18914.354000122306790070 |
ID : | 05-0067783 |
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Pascal:05-0067783Le document en format XML
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<front><div type="abstract" xml:lang="en">Purpose: To compare intensity of posterior capsule opacification (PCO) between the 1-piece and 3-piece haptic designs of an open-loop hydrophobic acrylic intraocular lens (IOL). Design: A randomized, patient- and examiner-masked clinical trial with intraindividual comparison. Participants: Fifty-two patients with bilateral age-related cataract (104 eyes). Methods: Each patient had cataract surgery in both eyes and received a 1-piece Acrysof IOL in one eye and a 3-piece Acrysof IOL in the fellow eye. Follow-up examinations were at 1 week, 1 month, 6 months, 1 year, and 2 years. Patients were examined at the slit lamp, visual acuity (VA) was determined, and standardized high-resolution digital retroillumination images of the posterior capsule were taken. The intensity of PCO was assessed subjectively at the slit lamp and objectively using automated image analysis software. Main Outcome Measure: Posterior capsule opacification score (scale, 0-10). Results: There was no significant difference between IOL styles in best-corrected VA, rhexis/IOL overlap, capsular folds, and amount of anterior capsule opacification during the follow-up period. One year postoperatively, the amount of regeneratory PCO was higher for the 1-piece Acrysof eyes (image analysis software score: 1.3) than for the 3-piece Acrysof eyes (score: 0.9; P = 0.002). However, 2 years postoperatively, there was no significant difference between the 2 IOL styles (1-piece: 1.5; 3-piece: 1.3; P = 0.3). Neodymium:yttrium-aluminum-garnet capsulotomy was not performed in the study. Conclusion: One year postoperatively, the 1 -piece Acrysof showed slightly more regeneratory PCO than the 3-piece Acrysof. However, 2 years postoperatively, the barrier effect of the 1-piece design was comparable to that of the 3-piece haptic design, with low PCO intensity.</div>
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<ET>Comparison of posterior capsule opacification between the 1-piece and 3-piece Acrysof intraocular lenses: Two-year results of a randomized trial</ET>
<AU>SACU (Stefan); FINDL (Oliver); MENAPACE (Rupert); BUEHL (Wolf); WIRTITSCH (Mathias)</AU>
<AF>Department of Ophthalmology, Medical University Vienna/Vienna/Autriche (1 aut., 2 aut., 3 aut., 4 aut., 5 aut.)</AF>
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<SO>Ophthalmology : (Rochester, MN); ISSN 0161-6420; Coden OPHTDG; Etats-Unis; Da. 2004; Vol. 111; No. 10; Pp. 1840-1846; Bibl. 29 ref.</SO>
<LA>Anglais</LA>
<EA>Purpose: To compare intensity of posterior capsule opacification (PCO) between the 1-piece and 3-piece haptic designs of an open-loop hydrophobic acrylic intraocular lens (IOL). Design: A randomized, patient- and examiner-masked clinical trial with intraindividual comparison. Participants: Fifty-two patients with bilateral age-related cataract (104 eyes). Methods: Each patient had cataract surgery in both eyes and received a 1-piece Acrysof IOL in one eye and a 3-piece Acrysof IOL in the fellow eye. Follow-up examinations were at 1 week, 1 month, 6 months, 1 year, and 2 years. Patients were examined at the slit lamp, visual acuity (VA) was determined, and standardized high-resolution digital retroillumination images of the posterior capsule were taken. The intensity of PCO was assessed subjectively at the slit lamp and objectively using automated image analysis software. Main Outcome Measure: Posterior capsule opacification score (scale, 0-10). Results: There was no significant difference between IOL styles in best-corrected VA, rhexis/IOL overlap, capsular folds, and amount of anterior capsule opacification during the follow-up period. One year postoperatively, the amount of regeneratory PCO was higher for the 1-piece Acrysof eyes (image analysis software score: 1.3) than for the 3-piece Acrysof eyes (score: 0.9; P = 0.002). However, 2 years postoperatively, there was no significant difference between the 2 IOL styles (1-piece: 1.5; 3-piece: 1.3; P = 0.3). Neodymium:yttrium-aluminum-garnet capsulotomy was not performed in the study. Conclusion: One year postoperatively, the 1 -piece Acrysof showed slightly more regeneratory PCO than the 3-piece Acrysof. However, 2 years postoperatively, the barrier effect of the 1-piece design was comparable to that of the 3-piece haptic design, with low PCO intensity.</EA>
<CC>002B25B</CC>
<FD>Etude comparative; Postérieur; Capsule; Gélule; Opacification; Lentille intraoculaire; Randomisation; Ophtalmologie; Traitement</FD>
<FG>Chirurgie</FG>
<ED>Comparative study; Posterior; Capsule; Hard capsule; Opacification; Intraocular lens; Randomization; Ophthalmology; Treatment</ED>
<EG>Surgery</EG>
<SD>Estudio comparativo; Posterior; Cápsula; Cápsula dura; Opacificación; Lente intraocular; Aleatorización; Oftalmología; Tratamiento</SD>
<LO>INIST-18914.354000122306790070</LO>
<ID>05-0067783</ID>
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