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Comparison of posterior capsule opacification between the 1-piece and 3-piece Acrysof intraocular lenses: Two-year results of a randomized trial

Identifieur interne : 000F08 ( PascalFrancis/Corpus ); précédent : 000F07; suivant : 000F09

Comparison of posterior capsule opacification between the 1-piece and 3-piece Acrysof intraocular lenses: Two-year results of a randomized trial

Auteurs : Stefan Sacu ; Oliver Findl ; Rupert Menapace ; Wolf Buehl ; Mathias Wirtitsch

Source :

RBID : Pascal:05-0067783

Descripteurs français

English descriptors

Abstract

Purpose: To compare intensity of posterior capsule opacification (PCO) between the 1-piece and 3-piece haptic designs of an open-loop hydrophobic acrylic intraocular lens (IOL). Design: A randomized, patient- and examiner-masked clinical trial with intraindividual comparison. Participants: Fifty-two patients with bilateral age-related cataract (104 eyes). Methods: Each patient had cataract surgery in both eyes and received a 1-piece Acrysof IOL in one eye and a 3-piece Acrysof IOL in the fellow eye. Follow-up examinations were at 1 week, 1 month, 6 months, 1 year, and 2 years. Patients were examined at the slit lamp, visual acuity (VA) was determined, and standardized high-resolution digital retroillumination images of the posterior capsule were taken. The intensity of PCO was assessed subjectively at the slit lamp and objectively using automated image analysis software. Main Outcome Measure: Posterior capsule opacification score (scale, 0-10). Results: There was no significant difference between IOL styles in best-corrected VA, rhexis/IOL overlap, capsular folds, and amount of anterior capsule opacification during the follow-up period. One year postoperatively, the amount of regeneratory PCO was higher for the 1-piece Acrysof eyes (image analysis software score: 1.3) than for the 3-piece Acrysof eyes (score: 0.9; P = 0.002). However, 2 years postoperatively, there was no significant difference between the 2 IOL styles (1-piece: 1.5; 3-piece: 1.3; P = 0.3). Neodymium:yttrium-aluminum-garnet capsulotomy was not performed in the study. Conclusion: One year postoperatively, the 1 -piece Acrysof showed slightly more regeneratory PCO than the 3-piece Acrysof. However, 2 years postoperatively, the barrier effect of the 1-piece design was comparable to that of the 3-piece haptic design, with low PCO intensity.

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Pour connaître la documentation sur le format Inist Standard.

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A01 01  1    @0 0161-6420
A02 01      @0 OPHTDG
A03   1    @0 Ophthalmology : (Rochester MN)
A05       @2 111
A06       @2 10
A08 01  1  ENG  @1 Comparison of posterior capsule opacification between the 1-piece and 3-piece Acrysof intraocular lenses: Two-year results of a randomized trial
A11 01  1    @1 SACU (Stefan)
A11 02  1    @1 FINDL (Oliver)
A11 03  1    @1 MENAPACE (Rupert)
A11 04  1    @1 BUEHL (Wolf)
A11 05  1    @1 WIRTITSCH (Mathias)
A14 01      @1 Department of Ophthalmology, Medical University Vienna @2 Vienna @3 AUT @Z 1 aut. @Z 2 aut. @Z 3 aut. @Z 4 aut. @Z 5 aut.
A20       @1 1840-1846
A21       @1 2004
A23 01      @0 ENG
A43 01      @1 INIST @2 18914 @5 354000122306790070
A44       @0 0000 @1 © 2005 INIST-CNRS. All rights reserved.
A45       @0 29 ref.
A47 01  1    @0 05-0067783
A60       @1 P
A61       @0 A
A64 01  1    @0 Ophthalmology : (Rochester, MN)
A66 01      @0 USA
C01 01    ENG  @0 Purpose: To compare intensity of posterior capsule opacification (PCO) between the 1-piece and 3-piece haptic designs of an open-loop hydrophobic acrylic intraocular lens (IOL). Design: A randomized, patient- and examiner-masked clinical trial with intraindividual comparison. Participants: Fifty-two patients with bilateral age-related cataract (104 eyes). Methods: Each patient had cataract surgery in both eyes and received a 1-piece Acrysof IOL in one eye and a 3-piece Acrysof IOL in the fellow eye. Follow-up examinations were at 1 week, 1 month, 6 months, 1 year, and 2 years. Patients were examined at the slit lamp, visual acuity (VA) was determined, and standardized high-resolution digital retroillumination images of the posterior capsule were taken. The intensity of PCO was assessed subjectively at the slit lamp and objectively using automated image analysis software. Main Outcome Measure: Posterior capsule opacification score (scale, 0-10). Results: There was no significant difference between IOL styles in best-corrected VA, rhexis/IOL overlap, capsular folds, and amount of anterior capsule opacification during the follow-up period. One year postoperatively, the amount of regeneratory PCO was higher for the 1-piece Acrysof eyes (image analysis software score: 1.3) than for the 3-piece Acrysof eyes (score: 0.9; P = 0.002). However, 2 years postoperatively, there was no significant difference between the 2 IOL styles (1-piece: 1.5; 3-piece: 1.3; P = 0.3). Neodymium:yttrium-aluminum-garnet capsulotomy was not performed in the study. Conclusion: One year postoperatively, the 1 -piece Acrysof showed slightly more regeneratory PCO than the 3-piece Acrysof. However, 2 years postoperatively, the barrier effect of the 1-piece design was comparable to that of the 3-piece haptic design, with low PCO intensity.
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C03 01  X  ENG  @0 Comparative study @5 02
C03 01  X  SPA  @0 Estudio comparativo @5 02
C03 02  X  FRE  @0 Postérieur @5 03
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C03 03  X  SPA  @0 Cápsula @5 05
C03 04  X  FRE  @0 Gélule @5 06
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C03 06  X  SPA  @0 Lente intraocular @5 09
C03 07  X  FRE  @0 Randomisation @5 11
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C03 07  X  SPA  @0 Aleatorización @5 11
C03 08  X  FRE  @0 Ophtalmologie @5 12
C03 08  X  ENG  @0 Ophthalmology @5 12
C03 08  X  SPA  @0 Oftalmología @5 12
C03 09  X  FRE  @0 Traitement @5 25
C03 09  X  ENG  @0 Treatment @5 25
C03 09  X  SPA  @0 Tratamiento @5 25
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C07 01  X  ENG  @0 Surgery @5 37
C07 01  X  SPA  @0 Cirugía @5 37
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Format Inist (serveur)

NO : PASCAL 05-0067783 INIST
ET : Comparison of posterior capsule opacification between the 1-piece and 3-piece Acrysof intraocular lenses: Two-year results of a randomized trial
AU : SACU (Stefan); FINDL (Oliver); MENAPACE (Rupert); BUEHL (Wolf); WIRTITSCH (Mathias)
AF : Department of Ophthalmology, Medical University Vienna/Vienna/Autriche (1 aut., 2 aut., 3 aut., 4 aut., 5 aut.)
DT : Publication en série; Niveau analytique
SO : Ophthalmology : (Rochester, MN); ISSN 0161-6420; Coden OPHTDG; Etats-Unis; Da. 2004; Vol. 111; No. 10; Pp. 1840-1846; Bibl. 29 ref.
LA : Anglais
EA : Purpose: To compare intensity of posterior capsule opacification (PCO) between the 1-piece and 3-piece haptic designs of an open-loop hydrophobic acrylic intraocular lens (IOL). Design: A randomized, patient- and examiner-masked clinical trial with intraindividual comparison. Participants: Fifty-two patients with bilateral age-related cataract (104 eyes). Methods: Each patient had cataract surgery in both eyes and received a 1-piece Acrysof IOL in one eye and a 3-piece Acrysof IOL in the fellow eye. Follow-up examinations were at 1 week, 1 month, 6 months, 1 year, and 2 years. Patients were examined at the slit lamp, visual acuity (VA) was determined, and standardized high-resolution digital retroillumination images of the posterior capsule were taken. The intensity of PCO was assessed subjectively at the slit lamp and objectively using automated image analysis software. Main Outcome Measure: Posterior capsule opacification score (scale, 0-10). Results: There was no significant difference between IOL styles in best-corrected VA, rhexis/IOL overlap, capsular folds, and amount of anterior capsule opacification during the follow-up period. One year postoperatively, the amount of regeneratory PCO was higher for the 1-piece Acrysof eyes (image analysis software score: 1.3) than for the 3-piece Acrysof eyes (score: 0.9; P = 0.002). However, 2 years postoperatively, there was no significant difference between the 2 IOL styles (1-piece: 1.5; 3-piece: 1.3; P = 0.3). Neodymium:yttrium-aluminum-garnet capsulotomy was not performed in the study. Conclusion: One year postoperatively, the 1 -piece Acrysof showed slightly more regeneratory PCO than the 3-piece Acrysof. However, 2 years postoperatively, the barrier effect of the 1-piece design was comparable to that of the 3-piece haptic design, with low PCO intensity.
CC : 002B25B
FD : Etude comparative; Postérieur; Capsule; Gélule; Opacification; Lentille intraoculaire; Randomisation; Ophtalmologie; Traitement
FG : Chirurgie
ED : Comparative study; Posterior; Capsule; Hard capsule; Opacification; Intraocular lens; Randomization; Ophthalmology; Treatment
EG : Surgery
SD : Estudio comparativo; Posterior; Cápsula; Cápsula dura; Opacificación; Lente intraocular; Aleatorización; Oftalmología; Tratamiento
LO : INIST-18914.354000122306790070
ID : 05-0067783

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<div type="abstract" xml:lang="en">Purpose: To compare intensity of posterior capsule opacification (PCO) between the 1-piece and 3-piece haptic designs of an open-loop hydrophobic acrylic intraocular lens (IOL). Design: A randomized, patient- and examiner-masked clinical trial with intraindividual comparison. Participants: Fifty-two patients with bilateral age-related cataract (104 eyes). Methods: Each patient had cataract surgery in both eyes and received a 1-piece Acrysof IOL in one eye and a 3-piece Acrysof IOL in the fellow eye. Follow-up examinations were at 1 week, 1 month, 6 months, 1 year, and 2 years. Patients were examined at the slit lamp, visual acuity (VA) was determined, and standardized high-resolution digital retroillumination images of the posterior capsule were taken. The intensity of PCO was assessed subjectively at the slit lamp and objectively using automated image analysis software. Main Outcome Measure: Posterior capsule opacification score (scale, 0-10). Results: There was no significant difference between IOL styles in best-corrected VA, rhexis/IOL overlap, capsular folds, and amount of anterior capsule opacification during the follow-up period. One year postoperatively, the amount of regeneratory PCO was higher for the 1-piece Acrysof eyes (image analysis software score: 1.3) than for the 3-piece Acrysof eyes (score: 0.9; P = 0.002). However, 2 years postoperatively, there was no significant difference between the 2 IOL styles (1-piece: 1.5; 3-piece: 1.3; P = 0.3). Neodymium:yttrium-aluminum-garnet capsulotomy was not performed in the study. Conclusion: One year postoperatively, the 1 -piece Acrysof showed slightly more regeneratory PCO than the 3-piece Acrysof. However, 2 years postoperatively, the barrier effect of the 1-piece design was comparable to that of the 3-piece haptic design, with low PCO intensity.</div>
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<fC03 i1="03" i2="X" l="FRE">
<s0>Capsule</s0>
<s5>05</s5>
</fC03>
<fC03 i1="03" i2="X" l="ENG">
<s0>Capsule</s0>
<s5>05</s5>
</fC03>
<fC03 i1="03" i2="X" l="SPA">
<s0>Cápsula</s0>
<s5>05</s5>
</fC03>
<fC03 i1="04" i2="X" l="FRE">
<s0>Gélule</s0>
<s5>06</s5>
</fC03>
<fC03 i1="04" i2="X" l="ENG">
<s0>Hard capsule</s0>
<s5>06</s5>
</fC03>
<fC03 i1="04" i2="X" l="SPA">
<s0>Cápsula dura</s0>
<s5>06</s5>
</fC03>
<fC03 i1="05" i2="X" l="FRE">
<s0>Opacification</s0>
<s5>08</s5>
</fC03>
<fC03 i1="05" i2="X" l="ENG">
<s0>Opacification</s0>
<s5>08</s5>
</fC03>
<fC03 i1="05" i2="X" l="SPA">
<s0>Opacificación</s0>
<s5>08</s5>
</fC03>
<fC03 i1="06" i2="X" l="FRE">
<s0>Lentille intraoculaire</s0>
<s5>09</s5>
</fC03>
<fC03 i1="06" i2="X" l="ENG">
<s0>Intraocular lens</s0>
<s5>09</s5>
</fC03>
<fC03 i1="06" i2="X" l="SPA">
<s0>Lente intraocular</s0>
<s5>09</s5>
</fC03>
<fC03 i1="07" i2="X" l="FRE">
<s0>Randomisation</s0>
<s5>11</s5>
</fC03>
<fC03 i1="07" i2="X" l="ENG">
<s0>Randomization</s0>
<s5>11</s5>
</fC03>
<fC03 i1="07" i2="X" l="SPA">
<s0>Aleatorización</s0>
<s5>11</s5>
</fC03>
<fC03 i1="08" i2="X" l="FRE">
<s0>Ophtalmologie</s0>
<s5>12</s5>
</fC03>
<fC03 i1="08" i2="X" l="ENG">
<s0>Ophthalmology</s0>
<s5>12</s5>
</fC03>
<fC03 i1="08" i2="X" l="SPA">
<s0>Oftalmología</s0>
<s5>12</s5>
</fC03>
<fC03 i1="09" i2="X" l="FRE">
<s0>Traitement</s0>
<s5>25</s5>
</fC03>
<fC03 i1="09" i2="X" l="ENG">
<s0>Treatment</s0>
<s5>25</s5>
</fC03>
<fC03 i1="09" i2="X" l="SPA">
<s0>Tratamiento</s0>
<s5>25</s5>
</fC03>
<fC07 i1="01" i2="X" l="FRE">
<s0>Chirurgie</s0>
<s5>37</s5>
</fC07>
<fC07 i1="01" i2="X" l="ENG">
<s0>Surgery</s0>
<s5>37</s5>
</fC07>
<fC07 i1="01" i2="X" l="SPA">
<s0>Cirugía</s0>
<s5>37</s5>
</fC07>
<fN21>
<s1>038</s1>
</fN21>
<fN44 i1="01">
<s1>OTO</s1>
</fN44>
<fN82>
<s1>OTO</s1>
</fN82>
</pA>
</standard>
<server>
<NO>PASCAL 05-0067783 INIST</NO>
<ET>Comparison of posterior capsule opacification between the 1-piece and 3-piece Acrysof intraocular lenses: Two-year results of a randomized trial</ET>
<AU>SACU (Stefan); FINDL (Oliver); MENAPACE (Rupert); BUEHL (Wolf); WIRTITSCH (Mathias)</AU>
<AF>Department of Ophthalmology, Medical University Vienna/Vienna/Autriche (1 aut., 2 aut., 3 aut., 4 aut., 5 aut.)</AF>
<DT>Publication en série; Niveau analytique</DT>
<SO>Ophthalmology : (Rochester, MN); ISSN 0161-6420; Coden OPHTDG; Etats-Unis; Da. 2004; Vol. 111; No. 10; Pp. 1840-1846; Bibl. 29 ref.</SO>
<LA>Anglais</LA>
<EA>Purpose: To compare intensity of posterior capsule opacification (PCO) between the 1-piece and 3-piece haptic designs of an open-loop hydrophobic acrylic intraocular lens (IOL). Design: A randomized, patient- and examiner-masked clinical trial with intraindividual comparison. Participants: Fifty-two patients with bilateral age-related cataract (104 eyes). Methods: Each patient had cataract surgery in both eyes and received a 1-piece Acrysof IOL in one eye and a 3-piece Acrysof IOL in the fellow eye. Follow-up examinations were at 1 week, 1 month, 6 months, 1 year, and 2 years. Patients were examined at the slit lamp, visual acuity (VA) was determined, and standardized high-resolution digital retroillumination images of the posterior capsule were taken. The intensity of PCO was assessed subjectively at the slit lamp and objectively using automated image analysis software. Main Outcome Measure: Posterior capsule opacification score (scale, 0-10). Results: There was no significant difference between IOL styles in best-corrected VA, rhexis/IOL overlap, capsular folds, and amount of anterior capsule opacification during the follow-up period. One year postoperatively, the amount of regeneratory PCO was higher for the 1-piece Acrysof eyes (image analysis software score: 1.3) than for the 3-piece Acrysof eyes (score: 0.9; P = 0.002). However, 2 years postoperatively, there was no significant difference between the 2 IOL styles (1-piece: 1.5; 3-piece: 1.3; P = 0.3). Neodymium:yttrium-aluminum-garnet capsulotomy was not performed in the study. Conclusion: One year postoperatively, the 1 -piece Acrysof showed slightly more regeneratory PCO than the 3-piece Acrysof. However, 2 years postoperatively, the barrier effect of the 1-piece design was comparable to that of the 3-piece haptic design, with low PCO intensity.</EA>
<CC>002B25B</CC>
<FD>Etude comparative; Postérieur; Capsule; Gélule; Opacification; Lentille intraoculaire; Randomisation; Ophtalmologie; Traitement</FD>
<FG>Chirurgie</FG>
<ED>Comparative study; Posterior; Capsule; Hard capsule; Opacification; Intraocular lens; Randomization; Ophthalmology; Treatment</ED>
<EG>Surgery</EG>
<SD>Estudio comparativo; Posterior; Cápsula; Cápsula dura; Opacificación; Lente intraocular; Aleatorización; Oftalmología; Tratamiento</SD>
<LO>INIST-18914.354000122306790070</LO>
<ID>05-0067783</ID>
</server>
</inist>
</record>

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