HapticV1, PascalFrancis, Corpus, bibRecord, 000C26

Evaluation of lens epithelial cell migration in vivo at the haptic-optic junction of a one-piece hydrophobic acrylic intraocular lens

Identifieur interne : 000C26 ( PascalFrancis/Corpus ); précédent : 000C25; suivant : 000C27

Evaluation of lens epithelial cell migration in vivo at the haptic-optic junction of a one-piece hydrophobic acrylic intraocular lens

Auteurs : Don R. Nixon ; David J. Apple

Source :

American journal of ophthalmology [ 0002-9394 ] ; 2006.

RBID : Pascal:06-0518044

Descripteurs français

Pascal (Inist)
- Evaluation, Cristallin, Cellule épithéliale, Migration, In vivo, Optique, Acrylique dérivé polymère, Ophtalmologie.

English descriptors

KwdEn :
- Acrylic polymer, Epithelial cell, Evaluation, In vivo, Lens, Migration, Ophthalmology, Optics.

Abstract

● PURPOSE: To evaluate the pattern of lens epithelial cell (LEC) ingrowth behind the intraocular lens (IOL) optic in patients implanted with the AcrySof SA60AT one-piece IOL. ● DESIGN: Retrospective case series. ● METHODS: Patients implanted with the AcrySof SA60AT one-piece IOL with complete overlap of the capsulorrhexis and IOL optic and no ocular pathology were selected from the practices of six surgeons. High-resolution digital images of the distribution of LECs were captured. Circumferential location and extent of LEC growth behind the optic were measured. ● RESULTS: Mean ± SD follow-up was 13.2 ± 1.7 months for 40 patients (mean age 72 years). LEC migration beyond the edge of the IOL optic was displayed by 57.5% (23/40) of patients. LECs migrated into the visual axis in 22.5% (9/40) of patients, leading to a visual acuity of <6/9 (20/30) in 10% (4/40) of patients. Cell migration was located preferentially at the optic-haptic junction. Serial photographs were used to monitor LEC migration over time. In some cases, LECs extended from the opposing optic-haptic junctions to converge in the center of the IOL, creating a path across the optic. ● CONCLUSIONS: The optic-haptic junction of the AcrySof one-piece IOL is a point of weakness in the barrier effect of the square-edge IOL design that provides migrating LECs access to the posterior capsule.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

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A02	`01`			`@0 AJOPAA`
A03		`1`		`@0 Am. j. ophthalmol.`
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A08	`01`	`1`	`ENG`	`@1 Evaluation of lens epithelial cell migration in vivo at the haptic-optic junction of a one-piece hydrophobic acrylic intraocular lens`
A11	`01`	`1`		`@1 NIXON (Don R.)`
A11	`02`	`1`		`@1 APPLE (David J.)`
A14	`01`			`@1 Trimed Eye Center @2 Barrie, Ontario @3 CAN @Z 1 aut.`
A14	`02`			`@1 Laboratories for Ophthalmic Device Research @2 Salt Lake City, Utah @3 USA @Z 2 aut.`
A20				`@1 557-562`
A21				`@1 2006`
A23	`01`			`@0 ENG`
A43	`01`			`@1 INIST @2 2012 @5 354000158777650030`
A44				`@0 0000 @1 © 2006 INIST-CNRS. All rights reserved.`
A45				`@0 17 ref.`
A47	`01`	`1`		`@0 06-0518044`
A60				`@1 P`
A61				`@0 A`
A64	`01`	`1`		`@0 American journal of ophthalmology`
A66	`01`			`@0 USA`
C01	`01`		`ENG`	@0 ● PURPOSE: To evaluate the pattern of lens epithelial cell (LEC) ingrowth behind the intraocular lens (IOL) optic in patients implanted with the AcrySof SA60AT one-piece IOL. ● DESIGN: Retrospective case series. ● METHODS: Patients implanted with the AcrySof SA60AT one-piece IOL with complete overlap of the capsulorrhexis and IOL optic and no ocular pathology were selected from the practices of six surgeons. High-resolution digital images of the distribution of LECs were captured. Circumferential location and extent of LEC growth behind the optic were measured. ● RESULTS: Mean ± SD follow-up was 13.2 ± 1.7 months for 40 patients (mean age 72 years). LEC migration beyond the edge of the IOL optic was displayed by 57.5% (23/40) of patients. LECs migrated into the visual axis in 22.5% (9/40) of patients, leading to a visual acuity of <6/9 (20/30) in 10% (4/40) of patients. Cell migration was located preferentially at the optic-haptic junction. Serial photographs were used to monitor LEC migration over time. In some cases, LECs extended from the opposing optic-haptic junctions to converge in the center of the IOL, creating a path across the optic. ● CONCLUSIONS: The optic-haptic junction of the AcrySof one-piece IOL is a point of weakness in the barrier effect of the square-edge IOL design that provides migrating LECs access to the posterior capsule.
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C03	`02`	`X`	`ENG`	`@0 Lens @5 03`
C03	`02`	`X`	`SPA`	`@0 Cristalino @5 03`
C03	`03`	`X`	`FRE`	`@0 Cellule épithéliale @5 05`
C03	`03`	`X`	`ENG`	`@0 Epithelial cell @5 05`
C03	`03`	`X`	`SPA`	`@0 Célula epitelial @5 05`
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C03	`04`	`X`	`ENG`	`@0 Migration @5 06`
C03	`04`	`X`	`SPA`	`@0 Migración @5 06`
C03	`05`	`X`	`FRE`	`@0 In vivo @5 08`
C03	`05`	`X`	`ENG`	`@0 In vivo @5 08`
C03	`05`	`X`	`SPA`	`@0 In vivo @5 08`
C03	`06`	`X`	`FRE`	`@0 Optique @5 09`
C03	`06`	`X`	`ENG`	`@0 Optics @5 09`
C03	`06`	`X`	`SPA`	`@0 Optica @5 09`
C03	`07`	`X`	`FRE`	`@0 Acrylique dérivé polymère @2 NK @5 11`
C03	`07`	`X`	`ENG`	`@0 Acrylic polymer @2 NK @5 11`
C03	`07`	`X`	`SPA`	`@0 Acrilico derivado polímero @2 NK @5 11`
C03	`08`	`X`	`FRE`	`@0 Ophtalmologie @5 12`
C03	`08`	`X`	`ENG`	`@0 Ophthalmology @5 12`
C03	`08`	`X`	`SPA`	`@0 Oftalmología @5 12`
N21				`@1 338`
N44	`01`			`@1 OTO`
N82				`@1 OTO`

Format Inist (serveur)

NO :	PASCAL 06-0518044 INIST
ET :	Evaluation of lens epithelial cell migration in vivo at the haptic-optic junction of a one-piece hydrophobic acrylic intraocular lens
AU :	NIXON (Don R.); APPLE (David J.)
AF :	Trimed Eye Center/Barrie, Ontario/Canada (1 aut.); Laboratories for Ophthalmic Device Research/Salt Lake City, Utah/Etats-Unis (2 aut.)
DT :	Publication en série; Niveau analytique
SO :	American journal of ophthalmology; ISSN 0002-9394; Coden AJOPAA; Etats-Unis; Da. 2006; Vol. 142; No. 4; Pp. 557-562; Bibl. 17 ref.
LA :	Anglais
EA :	● PURPOSE: To evaluate the pattern of lens epithelial cell (LEC) ingrowth behind the intraocular lens (IOL) optic in patients implanted with the AcrySof SA60AT one-piece IOL. ● DESIGN: Retrospective case series. ● METHODS: Patients implanted with the AcrySof SA60AT one-piece IOL with complete overlap of the capsulorrhexis and IOL optic and no ocular pathology were selected from the practices of six surgeons. High-resolution digital images of the distribution of LECs were captured. Circumferential location and extent of LEC growth behind the optic were measured. ● RESULTS: Mean ± SD follow-up was 13.2 ± 1.7 months for 40 patients (mean age 72 years). LEC migration beyond the edge of the IOL optic was displayed by 57.5% (23/40) of patients. LECs migrated into the visual axis in 22.5% (9/40) of patients, leading to a visual acuity of <6/9 (20/30) in 10% (4/40) of patients. Cell migration was located preferentially at the optic-haptic junction. Serial photographs were used to monitor LEC migration over time. In some cases, LECs extended from the opposing optic-haptic junctions to converge in the center of the IOL, creating a path across the optic. ● CONCLUSIONS: The optic-haptic junction of the AcrySof one-piece IOL is a point of weakness in the barrier effect of the square-edge IOL design that provides migrating LECs access to the posterior capsule.
CC :	002B09N
FD :	Evaluation; Cristallin; Cellule épithéliale; Migration; In vivo; Optique; Acrylique dérivé polymère; Ophtalmologie
ED :	Evaluation; Lens; Epithelial cell; Migration; In vivo; Optics; Acrylic polymer; Ophthalmology
SD :	Evaluación; Cristalino; Célula epitelial; Migración; In vivo; Optica; Acrilico derivado polímero; Oftalmología
LO :	INIST-2012.354000158777650030
ID :	06-0518044

Links to Exploration step

Pascal:06-0518044

Le document en format XML

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<front><div type="abstract" xml:lang="en">● PURPOSE: To evaluate the pattern of lens epithelial cell (LEC) ingrowth behind the intraocular lens (IOL) optic in patients implanted with the AcrySof SA60AT one-piece IOL. ● DESIGN: Retrospective case series. ● METHODS: Patients implanted with the AcrySof SA60AT one-piece IOL with complete overlap of the capsulorrhexis and IOL optic and no ocular pathology were selected from the practices of six surgeons. High-resolution digital images of the distribution of LECs were captured. Circumferential location and extent of LEC growth behind the optic were measured. ● RESULTS: Mean ± SD follow-up was 13.2 ± 1.7 months for 40 patients (mean age 72 years). LEC migration beyond the edge of the IOL optic was displayed by 57.5% (23/40) of patients. LECs migrated into the visual axis in 22.5% (9/40) of patients, leading to a visual acuity of <6/9 (20/30) in 10% (4/40) of patients. Cell migration was located preferentially at the optic-haptic junction. Serial photographs were used to monitor LEC migration over time. In some cases, LECs extended from the opposing optic-haptic junctions to converge in the center of the IOL, creating a path across the optic. ● CONCLUSIONS: The optic-haptic junction of the AcrySof one-piece IOL is a point of weakness in the barrier effect of the square-edge IOL design that provides migrating LECs access to the posterior capsule.</div>
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<ET>Evaluation of lens epithelial cell migration in vivo at the haptic-optic junction of a one-piece hydrophobic acrylic intraocular lens</ET>
<AU>NIXON (Don R.); APPLE (David J.)</AU>
<AF>Trimed Eye Center/Barrie, Ontario/Canada (1 aut.); Laboratories for Ophthalmic Device Research/Salt Lake City, Utah/Etats-Unis (2 aut.)</AF>
<DT>Publication en série; Niveau analytique</DT>
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<EA>● PURPOSE: To evaluate the pattern of lens epithelial cell (LEC) ingrowth behind the intraocular lens (IOL) optic in patients implanted with the AcrySof SA60AT one-piece IOL. ● DESIGN: Retrospective case series. ● METHODS: Patients implanted with the AcrySof SA60AT one-piece IOL with complete overlap of the capsulorrhexis and IOL optic and no ocular pathology were selected from the practices of six surgeons. High-resolution digital images of the distribution of LECs were captured. Circumferential location and extent of LEC growth behind the optic were measured. ● RESULTS: Mean ± SD follow-up was 13.2 ± 1.7 months for 40 patients (mean age 72 years). LEC migration beyond the edge of the IOL optic was displayed by 57.5% (23/40) of patients. LECs migrated into the visual axis in 22.5% (9/40) of patients, leading to a visual acuity of <6/9 (20/30) in 10% (4/40) of patients. Cell migration was located preferentially at the optic-haptic junction. Serial photographs were used to monitor LEC migration over time. In some cases, LECs extended from the opposing optic-haptic junctions to converge in the center of the IOL, creating a path across the optic. ● CONCLUSIONS: The optic-haptic junction of the AcrySof one-piece IOL is a point of weakness in the barrier effect of the square-edge IOL design that provides migrating LECs access to the posterior capsule.</EA>
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Evaluation of lens epithelial cell migration in vivo at the haptic-optic junction of a one-piece hydrophobic acrylic intraocular lens

Evaluation of lens epithelial cell migration in vivo at the haptic-optic junction of a one-piece hydrophobic acrylic intraocular lens

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Descripteurs français

English descriptors

Abstract

Notice en format standard (ISO 2709)

Format Inist (serveur)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

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