HapticV1, PascalFrancis, Corpus, bibRecord, 000378

Prevention of capsular bag opacification with a new hydrophilic acrylic disk-shaped intraocular lens

Identifieur interne : 000378 ( PascalFrancis/Corpus ); précédent : 000377; suivant : 000379

Prevention of capsular bag opacification with a new hydrophilic acrylic disk-shaped intraocular lens

Auteurs : Shaheen C. Kavoussi ; Liliana Werner ; Stanley R. Fuller ; Mark Hill ; Michael K. Burrow ; J. Steele Mcintyre ; Nick Mamalis

Source :

Journal of cataract and refractive surgery [ 0886-3350 ] ; 2011.

RBID : Pascal:12-0049226

Descripteurs français

Pascal (Inist)
- Prévention, Opacification, Acrylique dérivé polymère, Ophtalmologie, Chirurgie, Traitement.

English descriptors

KwdEn :
- Acrylic polymer, Opacification, Ophthalmology, Prevention, Surgery, Treatment.

Abstract

PURPOSE: To evaluate capsular bag opacification with a new disk-shaped single-piece hydrophilic acrylic intraocular lens (IOL) suspended between 2 haptic rings connected by a pillar of the haptic material and with a commercially available single-piece hydrophobic acrylic IOL in rabbits. SETTING: John A. Moran Eye Center, University of Utah, Salt Lake City, Utah, USA. DESIGN: Experimental study. METHODS: The study IOL was implanted in the right eyes of 5 New Zealand rabbits and the control IOL in the left eyes. Slitlamp examination was performed at weeks 1 through 5. After the rabbits were humanely killed, the globes were enucleated and examined by ultrasound. Capsular bag opacification scoring from the posterior aspect (Miyake-Apple view) was then performed, followed by histopathology. RESULTS: Trace honeycomb posterior capsule opacification (PCO) was noted in some study eyes. All control eyes developed moderate to marked PCO, which was more pronounced at the level of the optic-haptic junction. The mean PCO score was 0.4 ± 0.22 (SD) in the study group and 3.4 ± 0.54 in the control group (P=.000179, paired t test). Minimal proliferative cortical material was confined to the space between the anterior and posterior rings of the study IOL haptics. Anterior capsule opacification was absent in study eyes and mild in control eyes. There was no contact between the anterior capsule and the anterior surface of study IOLs. CONCLUSION: The peripheral rings of the study IOL, by expanding the capsular bag and preventing IOL surface contact with the anterior capsule, appear to prevent opacification of the capsular bag. Financial Disclosure: No author has a financial or proprietary interest in any material or method mentioned.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

A01	`01`	`1`		`@0 0886-3350`
A02	`01`			`@0 JCSUEV`
A03		`1`		`@0 J. cataract refractive surg.`
A05				`@2 37`
A06				`@2 12`
A08	`01`	`1`	`ENG`	`@1 Prevention of capsular bag opacification with a new hydrophilic acrylic disk-shaped intraocular lens`
A11	`01`	`1`		`@1 KAVOUSSI (Shaheen C.)`
A11	`02`	`1`		`@1 WERNER (Liliana)`
A11	`03`	`1`		`@1 FULLER (Stanley R.)`
A11	`04`	`1`		`@1 HILL (Mark)`
A11	`05`	`1`		`@1 BURROW (Michael K.)`
A11	`06`	`1`		`@1 STEELE MCINTYRE (J.)`
A11	`07`	`1`		`@1 MAMALIS (Nick)`
A14	`01`			`@1 Department of Ophthalmology and Visual Sciences, John A. Moran Eye Center, University of Utah, Salt Lake City @2 Utah @3 USA @Z 1 aut. @Z 2 aut. @Z 3 aut. @Z 4 aut. @Z 5 aut. @Z 6 aut. @Z 7 aut.`
A20				`@1 2194-2200`
A21				`@1 2011`
A23	`01`			`@0 ENG`
A43	`01`			`@1 INIST @2 20937 @5 354000507397890160`
A44				`@0 0000 @1 © 2012 INIST-CNRS. All rights reserved.`
A45				`@0 25 ref.`
A47	`01`	`1`		`@0 12-0049226`
A60				`@1 P`
A61				`@0 A`
A64	`01`	`1`		`@0 Journal of cataract and refractive surgery`
A66	`01`			`@0 USA`
C01	`01`		`ENG`	@0 PURPOSE: To evaluate capsular bag opacification with a new disk-shaped single-piece hydrophilic acrylic intraocular lens (IOL) suspended between 2 haptic rings connected by a pillar of the haptic material and with a commercially available single-piece hydrophobic acrylic IOL in rabbits. SETTING: John A. Moran Eye Center, University of Utah, Salt Lake City, Utah, USA. DESIGN: Experimental study. METHODS: The study IOL was implanted in the right eyes of 5 New Zealand rabbits and the control IOL in the left eyes. Slitlamp examination was performed at weeks 1 through 5. After the rabbits were humanely killed, the globes were enucleated and examined by ultrasound. Capsular bag opacification scoring from the posterior aspect (Miyake-Apple view) was then performed, followed by histopathology. RESULTS: Trace honeycomb posterior capsule opacification (PCO) was noted in some study eyes. All control eyes developed moderate to marked PCO, which was more pronounced at the level of the optic-haptic junction. The mean PCO score was 0.4 ± 0.22 (SD) in the study group and 3.4 ± 0.54 in the control group (P=.000179, paired t test). Minimal proliferative cortical material was confined to the space between the anterior and posterior rings of the study IOL haptics. Anterior capsule opacification was absent in study eyes and mild in control eyes. There was no contact between the anterior capsule and the anterior surface of study IOLs. CONCLUSION: The peripheral rings of the study IOL, by expanding the capsular bag and preventing IOL surface contact with the anterior capsule, appear to prevent opacification of the capsular bag. Financial Disclosure: No author has a financial or proprietary interest in any material or method mentioned.
C02	`01`	`X`		`@0 002B09`
C02	`02`	`X`		`@0 002B25B`
C03	`01`	`X`	`FRE`	`@0 Prévention @5 09`
C03	`01`	`X`	`ENG`	`@0 Prevention @5 09`
C03	`01`	`X`	`SPA`	`@0 Prevención @5 09`
C03	`02`	`X`	`FRE`	`@0 Opacification @5 10`
C03	`02`	`X`	`ENG`	`@0 Opacification @5 10`
C03	`02`	`X`	`SPA`	`@0 Opacificación @5 10`
C03	`03`	`X`	`FRE`	`@0 Acrylique dérivé polymère @2 NK @5 11`
C03	`03`	`X`	`ENG`	`@0 Acrylic polymer @2 NK @5 11`
C03	`03`	`X`	`SPA`	`@0 Acrilico derivado polímero @2 NK @5 11`
C03	`04`	`X`	`FRE`	`@0 Ophtalmologie @5 12`
C03	`04`	`X`	`ENG`	`@0 Ophthalmology @5 12`
C03	`04`	`X`	`SPA`	`@0 Oftalmología @5 12`
C03	`05`	`X`	`FRE`	`@0 Chirurgie @5 13`
C03	`05`	`X`	`ENG`	`@0 Surgery @5 13`
C03	`05`	`X`	`SPA`	`@0 Cirugía @5 13`
C03	`06`	`X`	`FRE`	`@0 Traitement @5 78`
C03	`06`	`X`	`ENG`	`@0 Treatment @5 78`
C03	`06`	`X`	`SPA`	`@0 Tratamiento @5 78`
N21				`@1 030`
N44	`01`			`@1 OTO`
N82				`@1 OTO`

Format Inist (serveur)

NO :	PASCAL 12-0049226 INIST
ET :	Prevention of capsular bag opacification with a new hydrophilic acrylic disk-shaped intraocular lens
AU :	KAVOUSSI (Shaheen C.); WERNER (Liliana); FULLER (Stanley R.); HILL (Mark); BURROW (Michael K.); STEELE MCINTYRE (J.); MAMALIS (Nick)
AF :	Department of Ophthalmology and Visual Sciences, John A. Moran Eye Center, University of Utah, Salt Lake City/Utah/Etats-Unis (1 aut., 2 aut., 3 aut., 4 aut., 5 aut., 6 aut., 7 aut.)
DT :	Publication en série; Niveau analytique
SO :	Journal of cataract and refractive surgery; ISSN 0886-3350; Coden JCSUEV; Etats-Unis; Da. 2011; Vol. 37; No. 12; Pp. 2194-2200; Bibl. 25 ref.
LA :	Anglais
EA :	PURPOSE: To evaluate capsular bag opacification with a new disk-shaped single-piece hydrophilic acrylic intraocular lens (IOL) suspended between 2 haptic rings connected by a pillar of the haptic material and with a commercially available single-piece hydrophobic acrylic IOL in rabbits. SETTING: John A. Moran Eye Center, University of Utah, Salt Lake City, Utah, USA. DESIGN: Experimental study. METHODS: The study IOL was implanted in the right eyes of 5 New Zealand rabbits and the control IOL in the left eyes. Slitlamp examination was performed at weeks 1 through 5. After the rabbits were humanely killed, the globes were enucleated and examined by ultrasound. Capsular bag opacification scoring from the posterior aspect (Miyake-Apple view) was then performed, followed by histopathology. RESULTS: Trace honeycomb posterior capsule opacification (PCO) was noted in some study eyes. All control eyes developed moderate to marked PCO, which was more pronounced at the level of the optic-haptic junction. The mean PCO score was 0.4 ± 0.22 (SD) in the study group and 3.4 ± 0.54 in the control group (P=.000179, paired t test). Minimal proliferative cortical material was confined to the space between the anterior and posterior rings of the study IOL haptics. Anterior capsule opacification was absent in study eyes and mild in control eyes. There was no contact between the anterior capsule and the anterior surface of study IOLs. CONCLUSION: The peripheral rings of the study IOL, by expanding the capsular bag and preventing IOL surface contact with the anterior capsule, appear to prevent opacification of the capsular bag. Financial Disclosure: No author has a financial or proprietary interest in any material or method mentioned.
CC :	002B09; 002B25B
FD :	Prévention; Opacification; Acrylique dérivé polymère; Ophtalmologie; Chirurgie; Traitement
ED :	Prevention; Opacification; Acrylic polymer; Ophthalmology; Surgery; Treatment
SD :	Prevención; Opacificación; Acrilico derivado polímero; Oftalmología; Cirugía; Tratamiento
LO :	INIST-20937.354000507397890160
ID :	12-0049226

Links to Exploration step

Pascal:12-0049226

Le document en format XML

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<series><title level="j" type="main">Journal of cataract and refractive surgery</title>
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<keywords scheme="Pascal" xml:lang="fr"><term>Prévention</term>
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<front><div type="abstract" xml:lang="en">PURPOSE: To evaluate capsular bag opacification with a new disk-shaped single-piece hydrophilic acrylic intraocular lens (IOL) suspended between 2 haptic rings connected by a pillar of the haptic material and with a commercially available single-piece hydrophobic acrylic IOL in rabbits. SETTING: John A. Moran Eye Center, University of Utah, Salt Lake City, Utah, USA. DESIGN: Experimental study. METHODS: The study IOL was implanted in the right eyes of 5 New Zealand rabbits and the control IOL in the left eyes. Slitlamp examination was performed at weeks 1 through 5. After the rabbits were humanely killed, the globes were enucleated and examined by ultrasound. Capsular bag opacification scoring from the posterior aspect (Miyake-Apple view) was then performed, followed by histopathology. RESULTS: Trace honeycomb posterior capsule opacification (PCO) was noted in some study eyes. All control eyes developed moderate to marked PCO, which was more pronounced at the level of the optic-haptic junction. The mean PCO score was 0.4 ± 0.22 (SD) in the study group and 3.4 ± 0.54 in the control group (P=.000179, paired t test). Minimal proliferative cortical material was confined to the space between the anterior and posterior rings of the study IOL haptics. Anterior capsule opacification was absent in study eyes and mild in control eyes. There was no contact between the anterior capsule and the anterior surface of study IOLs. CONCLUSION: The peripheral rings of the study IOL, by expanding the capsular bag and preventing IOL surface contact with the anterior capsule, appear to prevent opacification of the capsular bag. Financial Disclosure: No author has a financial or proprietary interest in any material or method mentioned.</div>
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<fA14 i1="01"><s1>Department of Ophthalmology and Visual Sciences, John A. Moran Eye Center, University of Utah, Salt Lake City</s1>
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<fA64 i1="01" i2="1"><s0>Journal of cataract and refractive surgery</s0>
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<fC01 i1="01" l="ENG"><s0>PURPOSE: To evaluate capsular bag opacification with a new disk-shaped single-piece hydrophilic acrylic intraocular lens (IOL) suspended between 2 haptic rings connected by a pillar of the haptic material and with a commercially available single-piece hydrophobic acrylic IOL in rabbits. SETTING: John A. Moran Eye Center, University of Utah, Salt Lake City, Utah, USA. DESIGN: Experimental study. METHODS: The study IOL was implanted in the right eyes of 5 New Zealand rabbits and the control IOL in the left eyes. Slitlamp examination was performed at weeks 1 through 5. After the rabbits were humanely killed, the globes were enucleated and examined by ultrasound. Capsular bag opacification scoring from the posterior aspect (Miyake-Apple view) was then performed, followed by histopathology. RESULTS: Trace honeycomb posterior capsule opacification (PCO) was noted in some study eyes. All control eyes developed moderate to marked PCO, which was more pronounced at the level of the optic-haptic junction. The mean PCO score was 0.4 ± 0.22 (SD) in the study group and 3.4 ± 0.54 in the control group (P=.000179, paired t test). Minimal proliferative cortical material was confined to the space between the anterior and posterior rings of the study IOL haptics. Anterior capsule opacification was absent in study eyes and mild in control eyes. There was no contact between the anterior capsule and the anterior surface of study IOLs. CONCLUSION: The peripheral rings of the study IOL, by expanding the capsular bag and preventing IOL surface contact with the anterior capsule, appear to prevent opacification of the capsular bag. Financial Disclosure: No author has a financial or proprietary interest in any material or method mentioned.</s0>
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<s5>13</s5>
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<server><NO>PASCAL 12-0049226 INIST</NO>
<ET>Prevention of capsular bag opacification with a new hydrophilic acrylic disk-shaped intraocular lens</ET>
<AU>KAVOUSSI (Shaheen C.); WERNER (Liliana); FULLER (Stanley R.); HILL (Mark); BURROW (Michael K.); STEELE MCINTYRE (J.); MAMALIS (Nick)</AU>
<AF>Department of Ophthalmology and Visual Sciences, John A. Moran Eye Center, University of Utah, Salt Lake City/Utah/Etats-Unis (1 aut., 2 aut., 3 aut., 4 aut., 5 aut., 6 aut., 7 aut.)</AF>
<DT>Publication en série; Niveau analytique</DT>
<SO>Journal of cataract and refractive surgery; ISSN 0886-3350; Coden JCSUEV; Etats-Unis; Da. 2011; Vol. 37; No. 12; Pp. 2194-2200; Bibl. 25 ref.</SO>
<LA>Anglais</LA>
<EA>PURPOSE: To evaluate capsular bag opacification with a new disk-shaped single-piece hydrophilic acrylic intraocular lens (IOL) suspended between 2 haptic rings connected by a pillar of the haptic material and with a commercially available single-piece hydrophobic acrylic IOL in rabbits. SETTING: John A. Moran Eye Center, University of Utah, Salt Lake City, Utah, USA. DESIGN: Experimental study. METHODS: The study IOL was implanted in the right eyes of 5 New Zealand rabbits and the control IOL in the left eyes. Slitlamp examination was performed at weeks 1 through 5. After the rabbits were humanely killed, the globes were enucleated and examined by ultrasound. Capsular bag opacification scoring from the posterior aspect (Miyake-Apple view) was then performed, followed by histopathology. RESULTS: Trace honeycomb posterior capsule opacification (PCO) was noted in some study eyes. All control eyes developed moderate to marked PCO, which was more pronounced at the level of the optic-haptic junction. The mean PCO score was 0.4 ± 0.22 (SD) in the study group and 3.4 ± 0.54 in the control group (P=.000179, paired t test). Minimal proliferative cortical material was confined to the space between the anterior and posterior rings of the study IOL haptics. Anterior capsule opacification was absent in study eyes and mild in control eyes. There was no contact between the anterior capsule and the anterior surface of study IOLs. CONCLUSION: The peripheral rings of the study IOL, by expanding the capsular bag and preventing IOL surface contact with the anterior capsule, appear to prevent opacification of the capsular bag. Financial Disclosure: No author has a financial or proprietary interest in any material or method mentioned.</EA>
<CC>002B09; 002B25B</CC>
<FD>Prévention; Opacification; Acrylique dérivé polymère; Ophtalmologie; Chirurgie; Traitement</FD>
<ED>Prevention; Opacification; Acrylic polymer; Ophthalmology; Surgery; Treatment</ED>
<SD>Prevención; Opacificación; Acrilico derivado polímero; Oftalmología; Cirugía; Tratamiento</SD>
<LO>INIST-20937.354000507397890160</LO>
<ID>12-0049226</ID>
</server>
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Prevention of capsular bag opacification with a new hydrophilic acrylic disk-shaped intraocular lens

Prevention of capsular bag opacification with a new hydrophilic acrylic disk-shaped intraocular lens

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