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12 year results of a prospective trial comparing poly(methyl methacrylate) and poly(hydroxyethyl methacrylate) intraocular lenses

Identifieur interne : 001310 ( PascalFrancis/Checkpoint ); précédent : 001309; suivant : 001311

12 year results of a prospective trial comparing poly(methyl methacrylate) and poly(hydroxyethyl methacrylate) intraocular lenses

Auteurs : A. J. Khan [Royaume-Uni] ; S. P. B. Percival [Royaume-Uni]

Source :

RBID : Pascal:99-0538184

Descripteurs français

English descriptors

Abstract

Purpose: To compare long-term biocompatibility of single-piece poly(methyl methacrylate) (PMMA) and poly(hydroxyethyl methacrylate) (P-HEMA) intraocular lenses (IOLS). Setting: District General Hospital, United Kingdom. Methods: In a prospective trial of 250 eyes that had uncomplicated extracapsular cataract extraction, 2 groups of 125 eyes each were matched for age and sex. One group received single-piece looped PMMA IOLs and the other, single-piece solid-haptic P-HEMA lOLs. In all eyes, the lOLs were implanted in the capsular bag at the time of surgery using the envelope technique. Results: Twelve years after surgery, 75 eyes were available for examination. In the PMMA group (40 eyes), 50% had a visual acuity of 20/20 and 50% had intact capsules, many of them with a degree of fibrosis. In the P-HEMA group (35 eyes), 71% had an acuity of 20/20 and 80% had intact capsules (P = .0085). Conclusion: In the long term, biocompatibility was better in the P-HEMA group than in the PMMA group.


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Pascal:99-0538184

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<div type="abstract" xml:lang="en">Purpose: To compare long-term biocompatibility of single-piece poly(methyl methacrylate) (PMMA) and poly(hydroxyethyl methacrylate) (P-HEMA) intraocular lenses (IOLS). Setting: District General Hospital, United Kingdom. Methods: In a prospective trial of 250 eyes that had uncomplicated extracapsular cataract extraction, 2 groups of 125 eyes each were matched for age and sex. One group received single-piece looped PMMA IOLs and the other, single-piece solid-haptic P-HEMA lOLs. In all eyes, the lOLs were implanted in the capsular bag at the time of surgery using the envelope technique. Results: Twelve years after surgery, 75 eyes were available for examination. In the PMMA group (40 eyes), 50% had a visual acuity of 20/20 and 50% had intact capsules, many of them with a degree of fibrosis. In the P-HEMA group (35 eyes), 71% had an acuity of 20/20 and 80% had intact capsules (P = .0085). Conclusion: In the long term, biocompatibility was better in the P-HEMA group than in the PMMA group.</div>
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