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Intraocular lens implantation in infant monkeys: clinical and histopathological findings.

Identifieur interne : 004658 ( Ncbi/Merge ); précédent : 004657; suivant : 004659

Intraocular lens implantation in infant monkeys: clinical and histopathological findings.

Auteurs : S R Lambert [États-Unis] ; H E Grossniklaus

Source :

RBID : pubmed:9278812

English descriptors

Abstract

To determine the long-term effects of intraocular lens (IOL) implantation in infant monkey eyes.

PubMed: 9278812

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pubmed:9278812

Le document en format XML

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<title xml:lang="en">Intraocular lens implantation in infant monkeys: clinical and histopathological findings.</title>
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<name sortKey="Lambert, S R" sort="Lambert, S R" uniqKey="Lambert S" first="S R" last="Lambert">S R Lambert</name>
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<nlm:affiliation>Emory Eye Center, Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia 30322, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Emory Eye Center, Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia 30322</wicri:regionArea>
<wicri:noRegion>Georgia 30322</wicri:noRegion>
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<author>
<name sortKey="Grossniklaus, H E" sort="Grossniklaus, H E" uniqKey="Grossniklaus H" first="H E" last="Grossniklaus">H E Grossniklaus</name>
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<title xml:lang="en">Intraocular lens implantation in infant monkeys: clinical and histopathological findings.</title>
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<name sortKey="Lambert, S R" sort="Lambert, S R" uniqKey="Lambert S" first="S R" last="Lambert">S R Lambert</name>
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<nlm:affiliation>Emory Eye Center, Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia 30322, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
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<name sortKey="Grossniklaus, H E" sort="Grossniklaus, H E" uniqKey="Grossniklaus H" first="H E" last="Grossniklaus">H E Grossniklaus</name>
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<title level="j">Journal of cataract and refractive surgery</title>
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<term>Animals</term>
<term>Animals, Newborn</term>
<term>Ciliary Body (pathology)</term>
<term>Follow-Up Studies</term>
<term>Iris (pathology)</term>
<term>Lenses, Intraocular (adverse effects)</term>
<term>Macaca mulatta</term>
<term>Methylmethacrylate</term>
<term>Methylmethacrylates</term>
<term>Postoperative Complications (etiology)</term>
<term>Postoperative Complications (pathology)</term>
<term>Refractive Errors (diagnosis)</term>
<term>Refractive Errors (etiology)</term>
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<keywords scheme="MESH" type="chemical" xml:lang="en">
<term>Methylmethacrylate</term>
<term>Methylmethacrylates</term>
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<keywords scheme="MESH" qualifier="adverse effects" xml:lang="en">
<term>Lenses, Intraocular</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en">
<term>Refractive Errors</term>
</keywords>
<keywords scheme="MESH" qualifier="etiology" xml:lang="en">
<term>Postoperative Complications</term>
<term>Refractive Errors</term>
</keywords>
<keywords scheme="MESH" qualifier="pathology" xml:lang="en">
<term>Ciliary Body</term>
<term>Iris</term>
<term>Postoperative Complications</term>
</keywords>
<keywords scheme="MESH" xml:lang="en">
<term>Animals</term>
<term>Animals, Newborn</term>
<term>Follow-Up Studies</term>
<term>Macaca mulatta</term>
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<div type="abstract" xml:lang="en">To determine the long-term effects of intraocular lens (IOL) implantation in infant monkey eyes.</div>
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<Year>1997</Year>
<Month>09</Month>
<Day>30</Day>
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<Year>1997</Year>
<Month>09</Month>
<Day>30</Day>
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<Year>2013</Year>
<Month>11</Month>
<Day>21</Day>
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<Volume>23 Suppl 1</Volume>
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<Year>1997</Year>
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<Title>Journal of cataract and refractive surgery</Title>
<ISOAbbreviation>J Cataract Refract Surg</ISOAbbreviation>
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<ArticleTitle>Intraocular lens implantation in infant monkeys: clinical and histopathological findings.</ArticleTitle>
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<Abstract>
<AbstractText Label="PURPOSE" NlmCategory="OBJECTIVE">To determine the long-term effects of intraocular lens (IOL) implantation in infant monkey eyes.</AbstractText>
<AbstractText Label="SETTING" NlmCategory="METHODS">Yerkes Regional Primate Research Center, Emory University School of Medicine, Atlanta, Georgia, USA.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">A 30.00 diopter (D), all-poly(methyl methacrylate) IOL with an overall diameter of 10.0 mm was implanted in the right eye of 11 infant monkeys. Seven monkeys developed postoperative complications and were not followed on a long-term basis. However, 4 monkeys were followed clinically for 4 1/2 years, after which their pseudophakic eyes were examined histopathologically.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">The final refractive error in the four pseudophakic eyes with long-term follow-up ranged from -4.75 to +0.75 D. Three of the four eyes had a Soemmering's ring. Only one haptic was in the capsular bag. whereas five had eroded into the iris root/ciliary body. The corneas and posterior segments of the eyes were normal.</AbstractText>
<AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">Two-thirds of the eyes having neonatal IOL implantation experienced significant postoperative complications. Haptic location was suboptimal in all four eyes followed for 4 1/2 years. The diameter of the IOLs implanted in these eyes was probably too large. Some of these complications might have been averted by implanting an IOL with a smaller diameter.</AbstractText>
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<Affiliation>Emory Eye Center, Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia 30322, USA.</Affiliation>
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