Posterior capsule opacification in rabbit eyes implanted with 1-piece and 3-piece hydrophobic acrylic intraocular lenses.
Identifieur interne : 000752 ( Ncbi/Merge ); précédent : 000751; suivant : 000753Posterior capsule opacification in rabbit eyes implanted with 1-piece and 3-piece hydrophobic acrylic intraocular lenses.
Auteurs : Liliana Werner [États-Unis] ; Nick Mamalis ; Andrea M. Izak ; Suresh K. Pandey ; Brandon L. Davis ; Chistian D. Nilson ; Christopher Weight ; David J. AppleSource :
- Journal of cataract and refractive surgery [ 0886-3350 ] ; 2005.
English descriptors
- KwdEn :
- Acrylic Resins, Animals, Biocompatible Materials, Cataract (etiology), Cataract (pathology), Epithelial Cells (pathology), Hydrophobic and Hydrophilic Interactions, Lens Capsule, Crystalline (pathology), Lens Implantation, Intraocular, Lenses, Intraocular (adverse effects), Postoperative Complications, Prosthesis Design, Rabbits.
- MESH :
- chemical : Acrylic Resins, Biocompatible Materials.
- adverse effects : Lenses, Intraocular.
- etiology : Cataract.
- pathology : Cataract, Epithelial Cells, Lens Capsule, Crystalline.
- Animals, Hydrophobic and Hydrophilic Interactions, Lens Implantation, Intraocular, Postoperative Complications, Prosthesis Design, Rabbits.
Abstract
To evaluate the outcome of posterior capsule opacification (PCO) after implantation in rabbit eyes of currently available 3-piece and 1-piece hydrophobic acrylic intraocular lenses (IOLs) with square optic edges.
DOI: 10.1016/j.jcrs.2004.06.088
PubMed: 15899460
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: 001937
- to stream PubMed, to step Curation: 001937
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pubmed:15899460Le document en format XML
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<author><name sortKey="Werner, Liliana" sort="Werner, Liliana" uniqKey="Werner L" first="Liliana" last="Werner">Liliana Werner</name>
<affiliation wicri:level="2"><nlm:affiliation>John A. Moran Eye Center, University of Utah, Salt Lake City, Utah, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>John A. Moran Eye Center, University of Utah, Salt Lake City, Utah</wicri:regionArea>
<placeName><region type="state">Utah</region>
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<author><name sortKey="Mamalis, Nick" sort="Mamalis, Nick" uniqKey="Mamalis N" first="Nick" last="Mamalis">Nick Mamalis</name>
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<author><name sortKey="Izak, Andrea M" sort="Izak, Andrea M" uniqKey="Izak A" first="Andrea M" last="Izak">Andrea M. Izak</name>
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<author><name sortKey="Pandey, Suresh K" sort="Pandey, Suresh K" uniqKey="Pandey S" first="Suresh K" last="Pandey">Suresh K. Pandey</name>
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<author><name sortKey="Davis, Brandon L" sort="Davis, Brandon L" uniqKey="Davis B" first="Brandon L" last="Davis">Brandon L. Davis</name>
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<author><name sortKey="Nilson, Chistian D" sort="Nilson, Chistian D" uniqKey="Nilson C" first="Chistian D" last="Nilson">Chistian D. Nilson</name>
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<author><name sortKey="Weight, Christopher" sort="Weight, Christopher" uniqKey="Weight C" first="Christopher" last="Weight">Christopher Weight</name>
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<author><name sortKey="Apple, David J" sort="Apple, David J" uniqKey="Apple D" first="David J" last="Apple">David J. Apple</name>
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<affiliation wicri:level="2"><nlm:affiliation>John A. Moran Eye Center, University of Utah, Salt Lake City, Utah, USA.</nlm:affiliation>
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<author><name sortKey="Izak, Andrea M" sort="Izak, Andrea M" uniqKey="Izak A" first="Andrea M" last="Izak">Andrea M. Izak</name>
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<author><name sortKey="Pandey, Suresh K" sort="Pandey, Suresh K" uniqKey="Pandey S" first="Suresh K" last="Pandey">Suresh K. Pandey</name>
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<author><name sortKey="Davis, Brandon L" sort="Davis, Brandon L" uniqKey="Davis B" first="Brandon L" last="Davis">Brandon L. Davis</name>
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<author><name sortKey="Nilson, Chistian D" sort="Nilson, Chistian D" uniqKey="Nilson C" first="Chistian D" last="Nilson">Chistian D. Nilson</name>
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<author><name sortKey="Weight, Christopher" sort="Weight, Christopher" uniqKey="Weight C" first="Christopher" last="Weight">Christopher Weight</name>
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<series><title level="j">Journal of cataract and refractive surgery</title>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Acrylic Resins</term>
<term>Animals</term>
<term>Biocompatible Materials</term>
<term>Cataract (etiology)</term>
<term>Cataract (pathology)</term>
<term>Epithelial Cells (pathology)</term>
<term>Hydrophobic and Hydrophilic Interactions</term>
<term>Lens Capsule, Crystalline (pathology)</term>
<term>Lens Implantation, Intraocular</term>
<term>Lenses, Intraocular (adverse effects)</term>
<term>Postoperative Complications</term>
<term>Prosthesis Design</term>
<term>Rabbits</term>
</keywords>
<keywords scheme="MESH" type="chemical" xml:lang="en"><term>Acrylic Resins</term>
<term>Biocompatible Materials</term>
</keywords>
<keywords scheme="MESH" qualifier="adverse effects" xml:lang="en"><term>Lenses, Intraocular</term>
</keywords>
<keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Cataract</term>
</keywords>
<keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Cataract</term>
<term>Epithelial Cells</term>
<term>Lens Capsule, Crystalline</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Animals</term>
<term>Hydrophobic and Hydrophilic Interactions</term>
<term>Lens Implantation, Intraocular</term>
<term>Postoperative Complications</term>
<term>Prosthesis Design</term>
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<front><div type="abstract" xml:lang="en">To evaluate the outcome of posterior capsule opacification (PCO) after implantation in rabbit eyes of currently available 3-piece and 1-piece hydrophobic acrylic intraocular lenses (IOLs) with square optic edges.</div>
</front>
</TEI>
<pubmed><MedlineCitation Owner="NLM" Status="MEDLINE"><PMID Version="1">15899460</PMID>
<DateCreated><Year>2005</Year>
<Month>05</Month>
<Day>18</Day>
</DateCreated>
<DateCompleted><Year>2005</Year>
<Month>06</Month>
<Day>16</Day>
</DateCompleted>
<DateRevised><Year>2010</Year>
<Month>11</Month>
<Day>18</Day>
</DateRevised>
<Article PubModel="Print"><Journal><ISSN IssnType="Print">0886-3350</ISSN>
<JournalIssue CitedMedium="Print"><Volume>31</Volume>
<Issue>4</Issue>
<PubDate><Year>2005</Year>
<Month>Apr</Month>
</PubDate>
</JournalIssue>
<Title>Journal of cataract and refractive surgery</Title>
<ISOAbbreviation>J Cataract Refract Surg</ISOAbbreviation>
</Journal>
<ArticleTitle>Posterior capsule opacification in rabbit eyes implanted with 1-piece and 3-piece hydrophobic acrylic intraocular lenses.</ArticleTitle>
<Pagination><MedlinePgn>805-11</MedlinePgn>
</Pagination>
<Abstract><AbstractText Label="PURPOSE" NlmCategory="OBJECTIVE">To evaluate the outcome of posterior capsule opacification (PCO) after implantation in rabbit eyes of currently available 3-piece and 1-piece hydrophobic acrylic intraocular lenses (IOLs) with square optic edges.</AbstractText>
<AbstractText Label="SETTING" NlmCategory="METHODS">John A. Moran Eye Center, University of Utah, Salt Lake City, Utah, USA.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">The 3-piece designs evaluated were the AR40e (Advanced Medical Optics Inc.) and the MA60AC (Alcon, Inc.); the 1-piece designs were the SA60AT and the SA30AT (Alcon, Inc.). Nine lenses of each type were implanted in a randomized manner by the same surgeon in 18 Dutch Belted pigmented rabbits. After a follow-up of 3 weeks, the rabbits were killed and analyses of the enucleated eyes were performed from the posterior or Miyake-Apple view. The intensity of central PCO, peripheral PCO, and Soemmering's ring formation was scored from 0 to 4. The area of Soemmering's ring formation was also scored from 0 to 4 based on the number of quadrants involved. Other parameters analyzed were capsulorhexis coverage of the IOL anterior surface, IOL centration, fixation, and presence of striae. Results from the posterior view were complemented by histopathologic evaluation of the eyes.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">No statistically significant difference was found between the 4 groups of IOLs in the parameters analyzed from the posterior view. When cell ingrowth occurred with the 1-piece designs, causing peripheral and central PCO formation, it was more likely to start at the optic-haptic junctions, as observed during the clinical follow-up with slitlamp examination and confirmed by gross and histopathologic analyses of the enucleated eyes.</AbstractText>
<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">The square, truncated optic edge is the most important IOL design feature for PCO prevention. The optic-haptic junctions of the 1-piece designs appear to be sites where the barrier effect of the truncated optic edge is less effective.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Werner</LastName>
<ForeName>Liliana</ForeName>
<Initials>L</Initials>
<AffiliationInfo><Affiliation>John A. Moran Eye Center, University of Utah, Salt Lake City, Utah, USA.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Mamalis</LastName>
<ForeName>Nick</ForeName>
<Initials>N</Initials>
</Author>
<Author ValidYN="Y"><LastName>Izak</LastName>
<ForeName>Andrea M</ForeName>
<Initials>AM</Initials>
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<Author ValidYN="Y"><LastName>Pandey</LastName>
<ForeName>Suresh K</ForeName>
<Initials>SK</Initials>
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<Author ValidYN="Y"><LastName>Davis</LastName>
<ForeName>Brandon L</ForeName>
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<Author ValidYN="Y"><LastName>Nilson</LastName>
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<Author ValidYN="Y"><LastName>Weight</LastName>
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<Author ValidYN="Y"><LastName>Apple</LastName>
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<Language>eng</Language>
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<MedlineJournalInfo><Country>United States</Country>
<MedlineTA>J Cataract Refract Surg</MedlineTA>
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<MeshHeadingList><MeshHeading><DescriptorName MajorTopicYN="Y" UI="D000180">Acrylic Resins</DescriptorName>
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<MeshHeading><DescriptorName MajorTopicYN="N" UI="D000818">Animals</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D001672">Biocompatible Materials</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D002386">Cataract</DescriptorName>
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<MeshHeading><DescriptorName MajorTopicYN="N" UI="D004847">Epithelial Cells</DescriptorName>
<QualifierName MajorTopicYN="N" UI="Q000473">pathology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D057927">Hydrophobic and Hydrophilic Interactions</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D007903">Lens Capsule, Crystalline</DescriptorName>
<QualifierName MajorTopicYN="Y" UI="Q000473">pathology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="Y" UI="D019654">Lens Implantation, Intraocular</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D007910">Lenses, Intraocular</DescriptorName>
<QualifierName MajorTopicYN="Y" UI="Q000009">adverse effects</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="Y" UI="D011183">Postoperative Complications</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D011474">Prosthesis Design</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D011817">Rabbits</DescriptorName>
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<name sortKey="Davis, Brandon L" sort="Davis, Brandon L" uniqKey="Davis B" first="Brandon L" last="Davis">Brandon L. Davis</name>
<name sortKey="Izak, Andrea M" sort="Izak, Andrea M" uniqKey="Izak A" first="Andrea M" last="Izak">Andrea M. Izak</name>
<name sortKey="Mamalis, Nick" sort="Mamalis, Nick" uniqKey="Mamalis N" first="Nick" last="Mamalis">Nick Mamalis</name>
<name sortKey="Nilson, Chistian D" sort="Nilson, Chistian D" uniqKey="Nilson C" first="Chistian D" last="Nilson">Chistian D. Nilson</name>
<name sortKey="Pandey, Suresh K" sort="Pandey, Suresh K" uniqKey="Pandey S" first="Suresh K" last="Pandey">Suresh K. Pandey</name>
<name sortKey="Weight, Christopher" sort="Weight, Christopher" uniqKey="Weight C" first="Christopher" last="Weight">Christopher Weight</name>
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<country name="États-Unis"><region name="Utah"><name sortKey="Werner, Liliana" sort="Werner, Liliana" uniqKey="Werner L" first="Liliana" last="Werner">Liliana Werner</name>
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