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Epidemiological evaluation of YAG capsulotomy incidence for posterior capsule opacification in various intraocular lenses in Japanese eyes

Identifieur interne : 003C24 ( Ncbi/Curation ); précédent : 003C23; suivant : 003C25

Epidemiological evaluation of YAG capsulotomy incidence for posterior capsule opacification in various intraocular lenses in Japanese eyes

Auteurs : Yutaro Nishi [Japon] ; Tomohiro Ikeda [Japon] ; Kayo Nishi [Japon] ; Osamu Mimura [Japon]

Source :

RBID : PMC:4562750

Abstract

Background and objective

We investigated the yttrium aluminum garnet (YAG) capsulotomy rates in various intraocular lenses (IOLs).

Study design/patients and methods

We retrospectively analyzed 23,440 eyes implanted with either MA60BM, MA60AC, VA-60BB, CeeOnEdge, Clariflex, Technis Z9002, SI-40NB, or UV26T IOLs. We calculated the YAG capsulotomy rates at 1, 3, 5, and 10 years post lens implantation.

Results

YAG capsulotomy rates at 3 years postimplantation for the eight groups of IOLs were, respectively, 3.7%, 3.9%, 23.7%, 3.4%, 4.5%, 4.7%, 10.4%, and 21.0%. YAG capsulotomy rates at 10 years postimplantation for the MA60BM and SI-40NB IOLs were, respectively, 9.1% and 15% (P<0.05). The average YAG rates for all sharp-edged and round-edged IOLs at 5 years postimplantation were, respectively, 5.2%±0.7% and 25.6%±9.0% (P<0.05).

Conclusion

In all studied IOLs, posterior capsule opacification prevention seemed to be associated with the posterior optic sharp-edge design. Round-edged silicone IOLs may also retard posterior capsule opacification formation, though not as much as sharp-edged IOLs. As the follow-up period progressed, round-edged silicone IOLs showed significantly higher YAG rates than sharp-edged IOLs.


Url:
DOI: 10.2147/OPTH.S89966
PubMed: 26366054
PubMed Central: 4562750

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<title xml:lang="en">Epidemiological evaluation of YAG capsulotomy incidence for posterior capsule opacification in various intraocular lenses in Japanese eyes</title>
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<name sortKey="Nishi, Yutaro" sort="Nishi, Yutaro" uniqKey="Nishi Y" first="Yutaro" last="Nishi">Yutaro Nishi</name>
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<nlm:aff id="af1-opth-9-1613">Department of Ophthalmology, Hyogo College of Medicine, Hyogo, Japan</nlm:aff>
<country xml:lang="fr">Japon</country>
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<nlm:aff id="af2-opth-9-1613">Nishi Eye Hospital, Osaka, Japan</nlm:aff>
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<name sortKey="Ikeda, Tomohiro" sort="Ikeda, Tomohiro" uniqKey="Ikeda T" first="Tomohiro" last="Ikeda">Tomohiro Ikeda</name>
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<nlm:aff id="af1-opth-9-1613">Department of Ophthalmology, Hyogo College of Medicine, Hyogo, Japan</nlm:aff>
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<name sortKey="Nishi, Kayo" sort="Nishi, Kayo" uniqKey="Nishi K" first="Kayo" last="Nishi">Kayo Nishi</name>
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<name sortKey="Mimura, Osamu" sort="Mimura, Osamu" uniqKey="Mimura O" first="Osamu" last="Mimura">Osamu Mimura</name>
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<title>Background and objective</title>
<p>We investigated the yttrium aluminum garnet (YAG) capsulotomy rates in various intraocular lenses (IOLs).</p>
</sec>
<sec>
<title>Study design/patients and methods</title>
<p>We retrospectively analyzed 23,440 eyes implanted with either MA60BM, MA60AC, VA-60BB, CeeOnEdge, Clariflex, Technis Z9002, SI-40NB, or UV26T IOLs. We calculated the YAG capsulotomy rates at 1, 3, 5, and 10 years post lens implantation.</p>
</sec>
<sec>
<title>Results</title>
<p>YAG capsulotomy rates at 3 years postimplantation for the eight groups of IOLs were, respectively, 3.7%, 3.9%, 23.7%, 3.4%, 4.5%, 4.7%, 10.4%, and 21.0%. YAG capsulotomy rates at 10 years postimplantation for the MA60BM and SI-40NB IOLs were, respectively, 9.1% and 15% (
<italic>P</italic>
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<italic>P</italic>
<0.05).</p>
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<title>Conclusion</title>
<p>In all studied IOLs, posterior capsule opacification prevention seemed to be associated with the posterior optic sharp-edge design. Round-edged silicone IOLs may also retard posterior capsule opacification formation, though not as much as sharp-edged IOLs. As the follow-up period progressed, round-edged silicone IOLs showed significantly higher YAG rates than sharp-edged IOLs.</p>
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