Cerebellar Activation During Discrete and not Continuous Timed Movements: an fMRI Study
Identifieur interne : 000B47 ( Ncbi/Curation ); précédent : 000B46; suivant : 000B48Cerebellar Activation During Discrete and not Continuous Timed Movements: an fMRI Study
Auteurs : Rebecca M. C. Spencer ; Timothy Verstynen ; Matthew Brett ; Richard IvrySource :
- NeuroImage [ 1053-8119 ] ; 2007.
Abstract
Individuals with cerebellar lesions are impaired in the timing of repetitive movements that involve the concatenation of discrete events such as tapping a finger. In contrast, these individuals perform comparably to controls when producing continuous repetitive movements. Based on this, we have proposed that the cerebellum plays a key role in event timing—the representation of the temporal relationship between salient events related to the movement (e.g., flexion onset or contact with a response surface). In the current study, we used fMRI to examine cerebellar activity during discrete and continuous rhythmic movements. Participants produced rhythmic movements with the index finger either making smooth, continuous transitions between flexion and extension or with a pause inserted before each flexion phase making the movement discrete. Lateral regions in lobule VI, ipsilateral to the moving hand were activated in a similar manner for both conditions. However, activation in the superior vermis was significantly greater when the movements were discrete compared to when the movements were continuous. This pattern was not evident in cortical regions within the field of view, including M1 and SMA. The results are consistent with the hypothesis that subregions of the cerebellum are selectively engaged during tasks involving event timing.
Url:
DOI: 10.1016/j.neuroimage.2007.03.009
PubMed: 17459731
PubMed Central: 1905817
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: Pour aller vers cette notice dans l'étape Curation :001055
- to stream Pmc, to step Curation: Pour aller vers cette notice dans l'étape Curation :001055
- to stream Pmc, to step Checkpoint: Pour aller vers cette notice dans l'étape Curation :002475
- to stream Ncbi, to step Merge: Pour aller vers cette notice dans l'étape Curation :000B47
Links to Exploration step
PMC:1905817Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Cerebellar Activation During Discrete and not Continuous Timed Movements: an fMRI Study</title><author><name sortKey="Spencer, Rebecca M C" sort="Spencer, Rebecca M C" uniqKey="Spencer R" first="Rebecca M. C." last="Spencer">Rebecca M. C. Spencer</name></author><author><name sortKey="Verstynen, Timothy" sort="Verstynen, Timothy" uniqKey="Verstynen T" first="Timothy" last="Verstynen">Timothy Verstynen</name></author><author><name sortKey="Brett, Matthew" sort="Brett, Matthew" uniqKey="Brett M" first="Matthew" last="Brett">Matthew Brett</name></author><author><name sortKey="Ivry, Richard" sort="Ivry, Richard" uniqKey="Ivry R" first="Richard" last="Ivry">Richard Ivry</name></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">17459731</idno><idno type="pmc">1905817</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1905817</idno><idno type="RBID">PMC:1905817</idno><idno type="doi">10.1016/j.neuroimage.2007.03.009</idno><date when="2007">2007</date><idno type="wicri:Area/Pmc/Corpus">001055</idno><idno type="wicri:Area/Pmc/Curation">001055</idno><idno type="wicri:Area/Pmc/Checkpoint">002475</idno><idno type="wicri:Area/Ncbi/Merge">000B47</idno><idno type="wicri:Area/Ncbi/Curation">000B47</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Cerebellar Activation During Discrete and not Continuous Timed Movements: an fMRI Study</title><author><name sortKey="Spencer, Rebecca M C" sort="Spencer, Rebecca M C" uniqKey="Spencer R" first="Rebecca M. C." last="Spencer">Rebecca M. C. Spencer</name></author><author><name sortKey="Verstynen, Timothy" sort="Verstynen, Timothy" uniqKey="Verstynen T" first="Timothy" last="Verstynen">Timothy Verstynen</name></author><author><name sortKey="Brett, Matthew" sort="Brett, Matthew" uniqKey="Brett M" first="Matthew" last="Brett">Matthew Brett</name></author><author><name sortKey="Ivry, Richard" sort="Ivry, Richard" uniqKey="Ivry R" first="Richard" last="Ivry">Richard Ivry</name></author></analytic><series><title level="j">NeuroImage</title><idno type="ISSN">1053-8119</idno><imprint><date when="2007">2007</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p id="P2">Individuals with cerebellar lesions are impaired in the timing of repetitive movements that involve the concatenation of discrete events such as tapping a finger. In contrast, these individuals perform comparably to controls when producing continuous repetitive movements. Based on this, we have proposed that the cerebellum plays a key role in event timing—the representation of the temporal relationship between salient events related to the movement (e.g., flexion onset or contact with a response surface). In the current study, we used fMRI to examine cerebellar activity during discrete and continuous rhythmic movements. Participants produced rhythmic movements with the index finger either making smooth, continuous transitions between flexion and extension or with a pause inserted before each flexion phase making the movement discrete. Lateral regions in lobule VI, ipsilateral to the moving hand were activated in a similar manner for both conditions. However, activation in the superior vermis was significantly greater when the movements were discrete compared to when the movements were continuous. This pattern was not evident in cortical regions within the field of view, including M1 and SMA. The results are consistent with the hypothesis that subregions of the cerebellum are selectively engaged during tasks involving event timing.</p></div></front></TEI></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Ticri/CIDE/explor/HapticV1/Data/Ncbi/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000B47 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Ncbi/Curation/biblio.hfd -nk 000B47 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Ticri/CIDE
|area= HapticV1
|flux= Ncbi
|étape= Curation
|type= RBID
|clé= PMC:1905817
|texte= Cerebellar Activation During Discrete and not Continuous Timed Movements: an fMRI Study
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Ncbi/Curation/RBID.i -Sk "pubmed:17459731" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Ncbi/Curation/biblio.hfd \
| NlmPubMed2Wicri -a HapticV1
| This area was generated with Dilib version V0.6.23. |  |