HapticV1, Main, Merge, bibRecord, 009062

Mini-haptics to improve capsular fixation of plate-haptic silicone intraocular lenses

Identifieur interne : 009062 ( Main/Merge ); précédent : 009061; suivant : 009063

Mini-haptics to improve capsular fixation of plate-haptic silicone intraocular lenses

Auteurs : D. G. Kent [États-Unis] ; QUN PENG [États-Unis] ; R. T. Isaacs [États-Unis] ; S. B. Whiteside [États-Unis] ; D. L. Barker [États-Unis] ; D. J. Apple [États-Unis]

Source :

Journal of cataract and refractive surgery [ 0886-3350 ] ; 1998.

RBID : Pascal:98-0266083

Descripteurs français

Pascal (Inist)
- Chirurgie, Oeil, Lentille intraoculaire, Fixation, Sac capsulaire, Siloxane polymère, Biomatériau, Technique, Amélioration, Homme.
Wicri :
- topic : Chirurgie, Biomatériau, Homme.

English descriptors

KwdEn :
- Biomaterial, Capsular bag, Eye, Fixation, Human, Improvement, Intraocular lens, Siloxane polymer, Surgery, Technique.

Abstract

Purpose: To evaluate the effects of a new mini-haptic design on the strength and stability of capsular bag fixation of plate-haptic silicone intraocular lenses (lOLs) and determine whether this design encourages the growth of regenerating lens material or fibrous tissue around the haptic biomaterial and thus improves lens fixation in the capsular bag. Setting : Center for Research on Ocular Therapeutics and Biodevices, Storm Eye Institute, Medical University of South Carolina, Department of Ophthalmology, Charleston, South Carolina, USA. Methods: Six rabbits had bilateral continuous curvilinear capsulorhexis, phacoemulsification, and plate-haptic silicone IOL implantation. Each rabbit had a small-hole plate IOL (Chiron C10UB) implanted in the right eye and a mini-haptic plate IOL (Chiron C40UB) in the left eye. All rabbits were killed at 2 months. The force required to extract one haptic from the capsular bag was measured with a digital force gauge. Histopathologic analysis was performed on all specimens. Results: The mini-haptic style lOLs required significantly more extraction force than the small-hole design (P = .011). Histopathologically, proliferating lens epithelial cells were observed growing circumferentially around the mini-haptics, causing a 360 degree synechia formation. This formation did not occur with the conventional small-hole plate lOLs used as the control. Conclusions: Lens epithelial cell proliferation around the mini-haptics significantly improved capsular bag fixation of the plate-haptic silicone IOL. This should decrease the incidence of clinical decentration and dislocation.

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Pascal:98-0266083

Le document en format XML

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<series><title level="j" type="main">Journal of cataract and refractive surgery</title>
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<idno type="ISSN">0886-3350</idno>
<imprint><date when="1998">1998</date>
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<seriesStmt><title level="j" type="main">Journal of cataract and refractive surgery</title>
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<idno type="ISSN">0886-3350</idno>
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</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Biomaterial</term>
<term>Capsular bag</term>
<term>Eye</term>
<term>Fixation</term>
<term>Human</term>
<term>Improvement</term>
<term>Intraocular lens</term>
<term>Siloxane polymer</term>
<term>Surgery</term>
<term>Technique</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Chirurgie</term>
<term>Oeil</term>
<term>Lentille intraoculaire</term>
<term>Fixation</term>
<term>Sac capsulaire</term>
<term>Siloxane polymère</term>
<term>Biomatériau</term>
<term>Technique</term>
<term>Amélioration</term>
<term>Homme</term>
</keywords>
<keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Chirurgie</term>
<term>Biomatériau</term>
<term>Homme</term>
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<front><div type="abstract" xml:lang="en">Purpose: To evaluate the effects of a new mini-haptic design on the strength and stability of capsular bag fixation of plate-haptic silicone intraocular lenses (lOLs) and determine whether this design encourages the growth of regenerating lens material or fibrous tissue around the haptic biomaterial and thus improves lens fixation in the capsular bag. Setting : Center for Research on Ocular Therapeutics and Biodevices, Storm Eye Institute, Medical University of South Carolina, Department of Ophthalmology, Charleston, South Carolina, USA. Methods: Six rabbits had bilateral continuous curvilinear capsulorhexis, phacoemulsification, and plate-haptic silicone IOL implantation. Each rabbit had a small-hole plate IOL (Chiron C10UB) implanted in the right eye and a mini-haptic plate IOL (Chiron C40UB) in the left eye. All rabbits were killed at 2 months. The force required to extract one haptic from the capsular bag was measured with a digital force gauge. Histopathologic analysis was performed on all specimens. Results: The mini-haptic style lOLs required significantly more extraction force than the small-hole design (P = .011). Histopathologically, proliferating lens epithelial cells were observed growing circumferentially around the mini-haptics, causing a 360 degree synechia formation. This formation did not occur with the conventional small-hole plate lOLs used as the control. Conclusions: Lens epithelial cell proliferation around the mini-haptics significantly improved capsular bag fixation of the plate-haptic silicone IOL. This should decrease the incidence of clinical decentration and dislocation.</div>
</front>
</TEI>
<affiliations><list><country><li>États-Unis</li>
</country>
<region><li>Caroline du Sud</li>
</region>
</list>
<tree><country name="États-Unis"><region name="Caroline du Sud"><name sortKey="Kent, D G" sort="Kent, D G" uniqKey="Kent D" first="D. G." last="Kent">D. G. Kent</name>
</region>
<name sortKey="Apple, D J" sort="Apple, D J" uniqKey="Apple D" first="D. J." last="Apple">D. J. Apple</name>
<name sortKey="Barker, D L" sort="Barker, D L" uniqKey="Barker D" first="D. L." last="Barker">D. L. Barker</name>
<name sortKey="Isaacs, R T" sort="Isaacs, R T" uniqKey="Isaacs R" first="R. T." last="Isaacs">R. T. Isaacs</name>
<name sortKey="Qun Peng" sort="Qun Peng" uniqKey="Qun Peng" last="Qun Peng">QUN PENG</name>
<name sortKey="Whiteside, S B" sort="Whiteside, S B" uniqKey="Whiteside S" first="S. B." last="Whiteside">S. B. Whiteside</name>
</country>
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</record>

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Mini-haptics to improve capsular fixation of plate-haptic silicone intraocular lenses

Mini-haptics to improve capsular fixation of plate-haptic silicone intraocular lenses

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri