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Randomized intraindividual comparison of posterior capsule opacification between a microincision intraocular lens and a conventional intraocular lens

Identifieur interne : 004938 ( Main/Merge ); précédent : 004937; suivant : 004939

Randomized intraindividual comparison of posterior capsule opacification between a microincision intraocular lens and a conventional intraocular lens

Auteurs : Georgia Cleary [Royaume-Uni, Australie] ; David J. Spalton [Royaume-Uni] ; Joanne Hancox [Royaume-Uni] ; James Boyce [Royaume-Uni] ; John Marshall [Royaume-Uni]

Source :

Journal of cataract and refractive surgery [ 0886-3350 ] ; 2009.

RBID : Pascal:09-0112078

Descripteurs français

Pascal (Inist)
- Comparaison intraindividuelle, Postérieur, Capsule, Opacification, Incision chirurgicale, Lentille intraoculaire, Ophtalmologie, Chirurgie, Traitement.
Wicri :
- topic : Chirurgie.

English descriptors

KwdEn :
- Capsule, Intraindividual comparison, Intraocular lens, Opacification, Ophthalmology, Posterior, Surgery, Surgical incision, Treatment.

Abstract

PURPOSE: To evaluate the differences in posterior capsule opacification (PCO) and visual and optical performance between a microincision intraocular lens (IOL) and a conventional IOL. SETTING: Ophthalmology Department, St. Thomas' Hospital, London, United Kingdom. METHODS: Patients with bilateral cataract were prospectively randomized to receive a HumanOptics MC611MI microincision IOL (microlens group) or an Alcon AcrySof MA60AC 3-piece IOL (control group) in either eye and were followed for 24 months. Best corrected visual acuity (BCVA) (logMAR) was measured; PCO was quantified by POCO software analysis of retroillumination images. Aberrations and modulation transfer function (MTF) were measured at the 24-month visit. RESULTS: The study enrolled 32 patients. The mean percentage area PCO was greater in the microlens group than in the control group from 3 months onward and was statistically significant from 12 months onward. The greatest difference in PCO between groups was at 24 months: mean 25.45% ± 34.51% (SD) in the microlens group versus 7.82% ± 13.35% in the control group (P = .029). The BCVA in the control group was slightly better at all time points; the difference between groups was statistically significant at 3, 6, and 12 months. No significant difference in aberrations was detected. The MTF curves were comparable for both lOLs. CONCLUSIONS: Both lOLs provided good visual performance. There was no evidence of distortion of the microincision IOL in the capsular bag. The microincision IOL had poorer PCO performance, which was visually significant and was caused by migration of lens epithelial cells through its broad optic-haptic junctions.

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Le document en format XML

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<author><name sortKey="Cleary, Georgia" sort="Cleary, Georgia" uniqKey="Cleary G" first="Georgia" last="Cleary">Georgia Cleary</name>
<affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Department of Ophthalmology, Rayne Institute, St. Thomas' Hospital</s1>
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<author><name sortKey="Marshall, John" sort="Marshall, John" uniqKey="Marshall J" first="John" last="Marshall">John Marshall</name>
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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Randomized intraindividual comparison of posterior capsule opacification between a microincision intraocular lens and a conventional intraocular lens</title>
<author><name sortKey="Cleary, Georgia" sort="Cleary, Georgia" uniqKey="Cleary G" first="Georgia" last="Cleary">Georgia Cleary</name>
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<author><name sortKey="Hancox, Joanne" sort="Hancox, Joanne" uniqKey="Hancox J" first="Joanne" last="Hancox">Joanne Hancox</name>
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<author><name sortKey="Marshall, John" sort="Marshall, John" uniqKey="Marshall J" first="John" last="Marshall">John Marshall</name>
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<series><title level="j" type="main">Journal of cataract and refractive surgery</title>
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<seriesStmt><title level="j" type="main">Journal of cataract and refractive surgery</title>
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</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Capsule</term>
<term>Intraindividual comparison</term>
<term>Intraocular lens</term>
<term>Opacification</term>
<term>Ophthalmology</term>
<term>Posterior</term>
<term>Surgery</term>
<term>Surgical incision</term>
<term>Treatment</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Comparaison intraindividuelle</term>
<term>Postérieur</term>
<term>Capsule</term>
<term>Opacification</term>
<term>Incision chirurgicale</term>
<term>Lentille intraoculaire</term>
<term>Ophtalmologie</term>
<term>Chirurgie</term>
<term>Traitement</term>
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<keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Chirurgie</term>
</keywords>
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<front><div type="abstract" xml:lang="en">PURPOSE: To evaluate the differences in posterior capsule opacification (PCO) and visual and optical performance between a microincision intraocular lens (IOL) and a conventional IOL. SETTING: Ophthalmology Department, St. Thomas' Hospital, London, United Kingdom. METHODS: Patients with bilateral cataract were prospectively randomized to receive a HumanOptics MC611MI microincision IOL (microlens group) or an Alcon AcrySof MA60AC 3-piece IOL (control group) in either eye and were followed for 24 months. Best corrected visual acuity (BCVA) (logMAR) was measured; PCO was quantified by POCO software analysis of retroillumination images. Aberrations and modulation transfer function (MTF) were measured at the 24-month visit. RESULTS: The study enrolled 32 patients. The mean percentage area PCO was greater in the microlens group than in the control group from 3 months onward and was statistically significant from 12 months onward. The greatest difference in PCO between groups was at 24 months: mean 25.45% ± 34.51% (SD) in the microlens group versus 7.82% ± 13.35% in the control group (P = .029). The BCVA in the control group was slightly better at all time points; the difference between groups was statistically significant at 3, 6, and 12 months. No significant difference in aberrations was detected. The MTF curves were comparable for both lOLs. CONCLUSIONS: Both lOLs provided good visual performance. There was no evidence of distortion of the microincision IOL in the capsular bag. The microincision IOL had poorer PCO performance, which was visually significant and was caused by migration of lens epithelial cells through its broad optic-haptic junctions.</div>
</front>
</TEI>
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<region><li>Angleterre</li>
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<tree><country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Cleary, Georgia" sort="Cleary, Georgia" uniqKey="Cleary G" first="Georgia" last="Cleary">Georgia Cleary</name>
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<name sortKey="Boyce, James" sort="Boyce, James" uniqKey="Boyce J" first="James" last="Boyce">James Boyce</name>
<name sortKey="Hancox, Joanne" sort="Hancox, Joanne" uniqKey="Hancox J" first="Joanne" last="Hancox">Joanne Hancox</name>
<name sortKey="Marshall, John" sort="Marshall, John" uniqKey="Marshall J" first="John" last="Marshall">John Marshall</name>
<name sortKey="Spalton, David J" sort="Spalton, David J" uniqKey="Spalton D" first="David J." last="Spalton">David J. Spalton</name>
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<country name="Australie"><noRegion><name sortKey="Cleary, Georgia" sort="Cleary, Georgia" uniqKey="Cleary G" first="Georgia" last="Cleary">Georgia Cleary</name>
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Randomized intraindividual comparison of posterior capsule opacification between a microincision intraocular lens and a conventional intraocular lens

Randomized intraindividual comparison of posterior capsule opacification between a microincision intraocular lens and a conventional intraocular lens

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri