Is My Model Good Enough? Best Practices for Verification and Validation of Musculoskeletal Models and Simulations of Movement
Identifieur interne : 000775 ( Main/Exploration ); précédent : 000774; suivant : 000776Is My Model Good Enough? Best Practices for Verification and Validation of Musculoskeletal Models and Simulations of Movement
Auteurs : Jennifer L. Hicks ; Thomas K. Uchida ; Ajay Seth ; Apoorva Rajagopal ; Scott L. DelpSource :
- Journal of Biomechanical Engineering [ 0148-0731 ] ; 2015.
Abstract
Computational modeling and simulation of neuromusculoskeletal (NMS) systems enables researchers and clinicians to study the complex dynamics underlying human and animal movement. NMS models use equations derived from physical laws and biology to help solve challenging real-world problems, from designing prosthetics that maximize running speed to developing exoskeletal devices that enable walking after a stroke. NMS modeling and simulation has proliferated in the biomechanics research community over the past 25 years, but the lack of verification and validation standards remains a major barrier to wider adoption and impact. The goal of this paper is to establish practical guidelines for verification and validation of NMS models and simulations that researchers, clinicians, reviewers, and others can adopt to evaluate the accuracy and credibility of modeling studies. In particular, we review a general process for verification and validation applied to NMS models and simulations, including careful formulation of a research question and methods, traditional verification and validation steps, and documentation and sharing of results for use and testing by other researchers. Modeling the NMS system and simulating its motion involves methods to represent neural control, musculoskeletal geometry, muscle–tendon dynamics, contact forces, and multibody dynamics. For each of these components, we review modeling choices and software verification guidelines; discuss variability, errors, uncertainty, and sensitivity relationships; and provide recommendations for verification and validation by comparing experimental data and testing robustness. We present a series of case studies to illustrate key principles. In closing, we discuss challenges the community must overcome to ensure that modeling and simulation are successfully used to solve the broad spectrum of problems that limit human mobility.
Url:
DOI: 10.1115/1.4029304
PubMed: 25474098
PubMed Central: 4321112
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 001374
- to stream Pmc, to step Curation: 001374
- to stream Pmc, to step Checkpoint: 000489
- to stream Ncbi, to step Merge: 003500
- to stream Ncbi, to step Curation: 003500
- to stream Ncbi, to step Checkpoint: 003500
- to stream Main, to step Merge: 000775
- to stream Main, to step Curation: 000775
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Is My Model Good Enough? Best Practices for Verification and Validation of Musculoskeletal Models and Simulations of Movement</title>
<author><name sortKey="Hicks, Jennifer L" sort="Hicks, Jennifer L" uniqKey="Hicks J" first="Jennifer L." last="Hicks">Jennifer L. Hicks</name>
</author>
<author><name sortKey="Uchida, Thomas K" sort="Uchida, Thomas K" uniqKey="Uchida T" first="Thomas K." last="Uchida">Thomas K. Uchida</name>
</author>
<author><name sortKey="Seth, Ajay" sort="Seth, Ajay" uniqKey="Seth A" first="Ajay" last="Seth">Ajay Seth</name>
</author>
<author><name sortKey="Rajagopal, Apoorva" sort="Rajagopal, Apoorva" uniqKey="Rajagopal A" first="Apoorva" last="Rajagopal">Apoorva Rajagopal</name>
</author>
<author><name sortKey="Delp, Scott L" sort="Delp, Scott L" uniqKey="Delp S" first="Scott L." last="Delp">Scott L. Delp</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">25474098</idno>
<idno type="pmc">4321112</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4321112</idno>
<idno type="RBID">PMC:4321112</idno>
<idno type="doi">10.1115/1.4029304</idno>
<date when="2015">2015</date>
<idno type="wicri:Area/Pmc/Corpus">001374</idno>
<idno type="wicri:Area/Pmc/Curation">001374</idno>
<idno type="wicri:Area/Pmc/Checkpoint">000489</idno>
<idno type="wicri:Area/Ncbi/Merge">003500</idno>
<idno type="wicri:Area/Ncbi/Curation">003500</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">003500</idno>
<idno type="wicri:doubleKey">0148-0731:2015:Hicks J:is:my:model</idno>
<idno type="wicri:Area/Main/Merge">000775</idno>
<idno type="wicri:Area/Main/Curation">000775</idno>
<idno type="wicri:Area/Main/Exploration">000775</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Is My Model Good Enough? Best Practices for Verification and Validation of Musculoskeletal Models and Simulations of Movement</title>
<author><name sortKey="Hicks, Jennifer L" sort="Hicks, Jennifer L" uniqKey="Hicks J" first="Jennifer L." last="Hicks">Jennifer L. Hicks</name>
</author>
<author><name sortKey="Uchida, Thomas K" sort="Uchida, Thomas K" uniqKey="Uchida T" first="Thomas K." last="Uchida">Thomas K. Uchida</name>
</author>
<author><name sortKey="Seth, Ajay" sort="Seth, Ajay" uniqKey="Seth A" first="Ajay" last="Seth">Ajay Seth</name>
</author>
<author><name sortKey="Rajagopal, Apoorva" sort="Rajagopal, Apoorva" uniqKey="Rajagopal A" first="Apoorva" last="Rajagopal">Apoorva Rajagopal</name>
</author>
<author><name sortKey="Delp, Scott L" sort="Delp, Scott L" uniqKey="Delp S" first="Scott L." last="Delp">Scott L. Delp</name>
</author>
</analytic>
<series><title level="j">Journal of Biomechanical Engineering</title>
<idno type="ISSN">0148-0731</idno>
<idno type="eISSN">1528-8951</idno>
<imprint><date when="2015">2015</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><p>Computational modeling and simulation of neuromusculoskeletal (NMS) systems enables researchers and clinicians to study the complex dynamics underlying human and animal movement. NMS models use equations derived from physical laws and biology to help solve challenging real-world problems, from designing prosthetics that maximize running speed to developing exoskeletal devices that enable walking after a stroke. NMS modeling and simulation has proliferated in the biomechanics research community over the past 25 years, but the lack of verification and validation standards remains a major barrier to wider adoption and impact. The goal of this paper is to establish practical guidelines for verification and validation of NMS models and simulations that researchers, clinicians, reviewers, and others can adopt to evaluate the accuracy and credibility of modeling studies. In particular, we review a general process for verification and validation applied to NMS models and simulations, including careful formulation of a research question and methods, traditional verification and validation steps, and documentation and sharing of results for use and testing by other researchers. Modeling the NMS system and simulating its motion involves methods to represent neural control, musculoskeletal geometry, muscle–tendon dynamics, contact forces, and multibody dynamics. For each of these components, we review modeling choices and software verification guidelines; discuss variability, errors, uncertainty, and sensitivity relationships; and provide recommendations for verification and validation by comparing experimental data and testing robustness. We present a series of case studies to illustrate key principles. In closing, we discuss challenges the community must overcome to ensure that modeling and simulation are successfully used to solve the broad spectrum of problems that limit human mobility.</p>
</div>
</front>
</TEI>
<affiliations><list></list>
<tree><noCountry><name sortKey="Delp, Scott L" sort="Delp, Scott L" uniqKey="Delp S" first="Scott L." last="Delp">Scott L. Delp</name>
<name sortKey="Hicks, Jennifer L" sort="Hicks, Jennifer L" uniqKey="Hicks J" first="Jennifer L." last="Hicks">Jennifer L. Hicks</name>
<name sortKey="Rajagopal, Apoorva" sort="Rajagopal, Apoorva" uniqKey="Rajagopal A" first="Apoorva" last="Rajagopal">Apoorva Rajagopal</name>
<name sortKey="Seth, Ajay" sort="Seth, Ajay" uniqKey="Seth A" first="Ajay" last="Seth">Ajay Seth</name>
<name sortKey="Uchida, Thomas K" sort="Uchida, Thomas K" uniqKey="Uchida T" first="Thomas K." last="Uchida">Thomas K. Uchida</name>
</noCountry>
</tree>
</affiliations>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Ticri/CIDE/explor/HapticV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000775 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000775 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Ticri/CIDE |area= HapticV1 |flux= Main |étape= Exploration |type= RBID |clé= PMC:4321112 |texte= Is My Model Good Enough? Best Practices for Verification and Validation of Musculoskeletal Models and Simulations of Movement }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:25474098" \ | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \ | NlmPubMed2Wicri -a HapticV1
![]() | This area was generated with Dilib version V0.6.23. | ![]() |