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Effect of tropicamide on aqueous flare before and after cataract surgery

Identifieur interne : 007E52 ( Main/Exploration ); précédent : 007E51; suivant : 007E53

Effect of tropicamide on aqueous flare before and after cataract surgery

Auteurs : Vanessa Petternel [Autriche] ; Oliver Findl [Autriche] ; Andreas Kruger [Autriche] ; Jörg Schauersberger [Autriche] ; Michael Amon [Autriche]

Source :

RBID : ISTEX:631041952464F6485B5F07793EC9BCD2EB33DA25

Abstract

Purpose To examine the effect of tropicamide on flare intensity under phakic and pseudophakic conditions and to differentiate between the possible mechanisms of action of tropicamide on aqueous flare.Setting Department of Ophthalmology, Vienna General Hospital, University of Vienna, Vienna, Austria.Methods In this prospective study, aqueous flare was measured with the laser flare–cell meter in 20 eyes of 20 patients with age-related cataract enrolled for cataract surgery. Measurements were performed before and 30, 90, and 180 minutes after pupil dilation with tropicamide 0.5%. This measurement was performed in the phakic eye on the day before surgery and in the pseudophakic eye on postoperative days 1, 3, 7, and 28.Results After tropicamide instillation, aqueous flare decreased preoperatively and on all postoperative days. There was a continuous flare decrease until 3 hours after instillation, reaching a maximum decrease of about 30%. Pupil diameter reached its maximum after 30 minutes.Conclusion Tropicamide significantly decreased aqueous flare, seemingly by pharmacological means, not volumetric changes. The time between drug application and measurement should be kept constant.

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DOI: 10.1016/S0886-3350(99)00404-6


Affiliations:


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Le document en format XML

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<div type="abstract" xml:lang="en">Purpose To examine the effect of tropicamide on flare intensity under phakic and pseudophakic conditions and to differentiate between the possible mechanisms of action of tropicamide on aqueous flare.Setting Department of Ophthalmology, Vienna General Hospital, University of Vienna, Vienna, Austria.Methods In this prospective study, aqueous flare was measured with the laser flare–cell meter in 20 eyes of 20 patients with age-related cataract enrolled for cataract surgery. Measurements were performed before and 30, 90, and 180 minutes after pupil dilation with tropicamide 0.5%. This measurement was performed in the phakic eye on the day before surgery and in the pseudophakic eye on postoperative days 1, 3, 7, and 28.Results After tropicamide instillation, aqueous flare decreased preoperatively and on all postoperative days. There was a continuous flare decrease until 3 hours after instillation, reaching a maximum decrease of about 30%. Pupil diameter reached its maximum after 30 minutes.Conclusion Tropicamide significantly decreased aqueous flare, seemingly by pharmacological means, not volumetric changes. The time between drug application and measurement should be kept constant.</div>
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