Mini-haptics to improve capsular fixation of plate-haptic silicone intraocular lenses
Identifieur interne : 002434 ( Istex/Curation ); précédent : 002433; suivant : 002435Mini-haptics to improve capsular fixation of plate-haptic silicone intraocular lenses
Auteurs : David G. Kent ; Qun Peng ; Robert T. Isaacs ; Stephen B. Whiteside ; Derek L. Barker ; David J. AppleSource :
- Journal of Cataract & Refractive Surgery [ 0886-3350 ] ; 1998.
Abstract
Purpose: To evaluate the effects of a new mini-haptic design on the strength and stability of capsular bag fixation of plate-haptic silicone intraocular lenses (IOLs) and determine whether this design encourages the growth of regenerating lens material or fibrous tissue around the haptic biomaterial and thus improves lens fixation in the capsular bag.Setting: Center for Research on Ocular Therapeutics and Biodevices, Storm Eye Institute, Medical University of South Carolina, Department of Ophthalmology, Charleston, South Carolina, USA.Methods: Six rabbits had bilateral continuous curvilinear capsulorhexis, phacoemulsification, and plate-haptic silicone IOL implantation. Each rabbit had a small-hole plate IOL (Chiron C10UB) implanted in the right eye and a mini-haptic plate IOL (Chiron C40UB) in the left eye. All rabbits were killed at 2 months. The force required to extract one haptic from the capsular bag was measured with a digital force gauge. Histopathologic analysis was performed on all specimens.Results: The mini-haptic style IOLs required significantly more extraction force than the small-hole design (P = .011). Histopathologically, proliferating lens epithelial cells were observed growing circumferentially around the mini-haptics, causing a 360 degree synechia formation. This formation did not occur with the conventional small-hole plate IOLs used as the control.Conclusions: Lens epithelial cell proliferation around the mini-haptics significantly improved capsular bag fixation of the plate-haptic silicone IOL. This should decrease the incidence of clinical decentration and dislocation.
Url:
DOI: 10.1016/S0886-3350(98)80263-0
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David G. Kent<affiliation><mods:affiliation>From the Center for Research on Ocular Therapeutics and Biodevices (formerly Center for Intraocular Lens Research), Storm Eye Institute, Medical University of South Carolina, Charleston, South Carolina, USA.From the Center for Research on Ocular Therapeutics and Biodevices (formerly Center for Intraocular Lens Research), Storm Eye Institute, Medical University of South CarolinaCharlestonSouth CarolinaUSA</mods:affiliation><wicri:noCountry code="subField">Medical University of South CarolinaCharlestonSouth CarolinaUSA</wicri:noCountry></affiliation><affiliation><mods:affiliation>From the Center for Research on Ocular Therapeutics and Biodevices (formerly Center for Intraocular Lens Research), Storm Eye Institute, Medical University of South Carolina, Charleston, South Carolina, USA.From the Center for Research on Ocular Therapeutics and Biodevices (formerly Center for Intraocular Lens Research), Storm Eye Institute, Medical University of South CarolinaCharlestonSouth CarolinaUSA</mods:affiliation><wicri:noCountry code="subField">Medical University of South CarolinaCharlestonSouth CarolinaUSA</wicri:noCountry></affiliation><affiliation><mods:affiliation>From the Center for Research on Ocular Therapeutics and Biodevices (formerly Center for Intraocular Lens Research), Storm Eye Institute, Medical University of South Carolina, Charleston, South Carolina, USA.From the Center for Research on Ocular Therapeutics and Biodevices (formerly Center for Intraocular Lens Research), Storm Eye Institute, Medical University of South CarolinaCharlestonSouth CarolinaUSA</mods:affiliation><wicri:noCountry code="subField">Medical University of South CarolinaCharlestonSouth CarolinaUSA</wicri:noCountry></affiliation><affiliation><mods:affiliation>From the Center for Research on Ocular Therapeutics and Biodevices (formerly Center for Intraocular Lens Research), Storm Eye Institute, Medical University of South Carolina, Charleston, South Carolina, USA.From the Center for Research on Ocular Therapeutics and Biodevices (formerly Center for Intraocular Lens Research), Storm Eye Institute, Medical University of South CarolinaCharlestonSouth CarolinaUSA</mods:affiliation><wicri:noCountry code="subField">Medical University of South CarolinaCharlestonSouth CarolinaUSA</wicri:noCountry></affiliation><affiliation><mods:affiliation>From the Center for Research on Ocular Therapeutics and Biodevices (formerly Center for Intraocular Lens Research), Storm Eye Institute, Medical University of South Carolina, Charleston, South Carolina, USA.From the Center for Research on Ocular Therapeutics and Biodevices (formerly Center for Intraocular Lens Research), Storm Eye Institute, Medical University of South CarolinaCharlestonSouth CarolinaUSA</mods:affiliation><wicri:noCountry code="subField">Medical University of South CarolinaCharlestonSouth CarolinaUSA</wicri:noCountry></affiliation><affiliation><mods:affiliation>From the Center for Research on Ocular Therapeutics and Biodevices (formerly Center for Intraocular Lens Research), Storm Eye Institute, Medical University of South Carolina, Charleston, South Carolina, USA.From the Center for Research on Ocular Therapeutics and Biodevices (formerly Center for Intraocular Lens Research), Storm Eye Institute, Medical University of South CarolinaCharlestonSouth CarolinaUSA</mods:affiliation><wicri:noCountry code="subField">Medical University of South CarolinaCharlestonSouth CarolinaUSA</wicri:noCountry></affiliation>Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Mini-haptics to improve capsular fixation of plate-haptic silicone intraocular lenses</title><author><name sortKey="Kent, David G" sort="Kent, David G" uniqKey="Kent D" first="David G." last="Kent">David G. Kent</name><affiliation><mods:affiliation>From the Center for Research on Ocular Therapeutics and Biodevices (formerly Center for Intraocular Lens Research), Storm Eye Institute, Medical University of South Carolina, Charleston, South Carolina, USA.From the Center for Research on Ocular Therapeutics and Biodevices (formerly Center for Intraocular Lens Research), Storm Eye Institute, Medical University of South CarolinaCharlestonSouth CarolinaUSA</mods:affiliation><wicri:noCountry code="subField">Medical University of South CarolinaCharlestonSouth CarolinaUSA</wicri:noCountry></affiliation></author><author><name sortKey="Peng, Qun" sort="Peng, Qun" uniqKey="Peng Q" first="Qun" last="Peng">Qun Peng</name><affiliation><mods:affiliation>From the Center for Research on Ocular Therapeutics and Biodevices (formerly Center for Intraocular Lens Research), Storm Eye Institute, Medical University of South Carolina, Charleston, South Carolina, USA.From the Center for Research on Ocular Therapeutics and Biodevices (formerly Center for Intraocular Lens Research), Storm Eye Institute, Medical University of South CarolinaCharlestonSouth CarolinaUSA</mods:affiliation><wicri:noCountry code="subField">Medical University of South CarolinaCharlestonSouth CarolinaUSA</wicri:noCountry></affiliation></author><author><name sortKey="Isaacs, Robert T" sort="Isaacs, Robert T" uniqKey="Isaacs R" first="Robert T." last="Isaacs">Robert T. Isaacs</name><affiliation><mods:affiliation>From the Center for Research on Ocular Therapeutics and Biodevices (formerly Center for Intraocular Lens Research), Storm Eye Institute, Medical University of South Carolina, Charleston, South Carolina, USA.From the Center for Research on Ocular Therapeutics and Biodevices (formerly Center for Intraocular Lens Research), Storm Eye Institute, Medical University of South CarolinaCharlestonSouth CarolinaUSA</mods:affiliation><wicri:noCountry code="subField">Medical University of South CarolinaCharlestonSouth CarolinaUSA</wicri:noCountry></affiliation></author><author><name sortKey="Whiteside, Stephen B" sort="Whiteside, Stephen B" uniqKey="Whiteside S" first="Stephen B." last="Whiteside">Stephen B. Whiteside</name><affiliation><mods:affiliation>From the Center for Research on Ocular Therapeutics and Biodevices (formerly Center for Intraocular Lens Research), Storm Eye Institute, Medical University of South Carolina, Charleston, South Carolina, USA.From the Center for Research on Ocular Therapeutics and Biodevices (formerly Center for Intraocular Lens Research), Storm Eye Institute, Medical University of South CarolinaCharlestonSouth CarolinaUSA</mods:affiliation><wicri:noCountry code="subField">Medical University of South CarolinaCharlestonSouth CarolinaUSA</wicri:noCountry></affiliation></author><author><name sortKey="Barker, Derek L" sort="Barker, Derek L" uniqKey="Barker D" first="Derek L." last="Barker">Derek L. Barker</name><affiliation><mods:affiliation>From the Center for Research on Ocular Therapeutics and Biodevices (formerly Center for Intraocular Lens Research), Storm Eye Institute, Medical University of South Carolina, Charleston, South Carolina, USA.From the Center for Research on Ocular Therapeutics and Biodevices (formerly Center for Intraocular Lens Research), Storm Eye Institute, Medical University of South CarolinaCharlestonSouth CarolinaUSA</mods:affiliation><wicri:noCountry code="subField">Medical University of South CarolinaCharlestonSouth CarolinaUSA</wicri:noCountry></affiliation></author><author><name sortKey="Apple, David J" sort="Apple, David J" uniqKey="Apple D" first="David J." last="Apple">David J. Apple</name><affiliation><mods:affiliation>From the Center for Research on Ocular Therapeutics and Biodevices (formerly Center for Intraocular Lens Research), Storm Eye Institute, Medical University of South Carolina, Charleston, South Carolina, USA.From the Center for Research on Ocular Therapeutics and Biodevices (formerly Center for Intraocular Lens Research), Storm Eye Institute, Medical University of South CarolinaCharlestonSouth CarolinaUSA</mods:affiliation><wicri:noCountry code="subField">Medical University of South CarolinaCharlestonSouth CarolinaUSA</wicri:noCountry></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:5ABA5A942A8EEFA32774542FDF9C3360552E54C8</idno><date when="1998" year="1998">1998</date><idno type="doi">10.1016/S0886-3350(98)80263-0</idno><idno type="url">https://api.istex.fr/document/5ABA5A942A8EEFA32774542FDF9C3360552E54C8/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">002434</idno><idno type="wicri:Area/Istex/Curation">002434</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Mini-haptics to improve capsular fixation of plate-haptic silicone intraocular lenses</title><author><name sortKey="Kent, David G" sort="Kent, David G" uniqKey="Kent D" first="David G." last="Kent">David G. Kent</name><affiliation><mods:affiliation>From the Center for Research on Ocular Therapeutics and Biodevices (formerly Center for Intraocular Lens Research), Storm Eye Institute, Medical University of South Carolina, Charleston, South Carolina, USA.From the Center for Research on Ocular Therapeutics and Biodevices (formerly Center for Intraocular Lens Research), Storm Eye Institute, Medical University of South CarolinaCharlestonSouth CarolinaUSA</mods:affiliation><wicri:noCountry code="subField">Medical University of South CarolinaCharlestonSouth CarolinaUSA</wicri:noCountry></affiliation></author><author><name sortKey="Peng, Qun" sort="Peng, Qun" uniqKey="Peng Q" first="Qun" last="Peng">Qun Peng</name><affiliation><mods:affiliation>From the Center for Research on Ocular Therapeutics and Biodevices (formerly Center for Intraocular Lens Research), Storm Eye Institute, Medical University of South Carolina, Charleston, South Carolina, USA.From the Center for Research on Ocular Therapeutics and Biodevices (formerly Center for Intraocular Lens Research), Storm Eye Institute, Medical University of South CarolinaCharlestonSouth CarolinaUSA</mods:affiliation><wicri:noCountry code="subField">Medical University of South CarolinaCharlestonSouth CarolinaUSA</wicri:noCountry></affiliation></author><author><name sortKey="Isaacs, Robert T" sort="Isaacs, Robert T" uniqKey="Isaacs R" first="Robert T." last="Isaacs">Robert T. Isaacs</name><affiliation><mods:affiliation>From the Center for Research on Ocular Therapeutics and Biodevices (formerly Center for Intraocular Lens Research), Storm Eye Institute, Medical University of South Carolina, Charleston, South Carolina, USA.From the Center for Research on Ocular Therapeutics and Biodevices (formerly Center for Intraocular Lens Research), Storm Eye Institute, Medical University of South CarolinaCharlestonSouth CarolinaUSA</mods:affiliation><wicri:noCountry code="subField">Medical University of South CarolinaCharlestonSouth CarolinaUSA</wicri:noCountry></affiliation></author><author><name sortKey="Whiteside, Stephen B" sort="Whiteside, Stephen B" uniqKey="Whiteside S" first="Stephen B." last="Whiteside">Stephen B. Whiteside</name><affiliation><mods:affiliation>From the Center for Research on Ocular Therapeutics and Biodevices (formerly Center for Intraocular Lens Research), Storm Eye Institute, Medical University of South Carolina, Charleston, South Carolina, USA.From the Center for Research on Ocular Therapeutics and Biodevices (formerly Center for Intraocular Lens Research), Storm Eye Institute, Medical University of South CarolinaCharlestonSouth CarolinaUSA</mods:affiliation><wicri:noCountry code="subField">Medical University of South CarolinaCharlestonSouth CarolinaUSA</wicri:noCountry></affiliation></author><author><name sortKey="Barker, Derek L" sort="Barker, Derek L" uniqKey="Barker D" first="Derek L." last="Barker">Derek L. Barker</name><affiliation><mods:affiliation>From the Center for Research on Ocular Therapeutics and Biodevices (formerly Center for Intraocular Lens Research), Storm Eye Institute, Medical University of South Carolina, Charleston, South Carolina, USA.From the Center for Research on Ocular Therapeutics and Biodevices (formerly Center for Intraocular Lens Research), Storm Eye Institute, Medical University of South CarolinaCharlestonSouth CarolinaUSA</mods:affiliation><wicri:noCountry code="subField">Medical University of South CarolinaCharlestonSouth CarolinaUSA</wicri:noCountry></affiliation></author><author><name sortKey="Apple, David J" sort="Apple, David J" uniqKey="Apple D" first="David J." last="Apple">David J. Apple</name><affiliation><mods:affiliation>From the Center for Research on Ocular Therapeutics and Biodevices (formerly Center for Intraocular Lens Research), Storm Eye Institute, Medical University of South Carolina, Charleston, South Carolina, USA.From the Center for Research on Ocular Therapeutics and Biodevices (formerly Center for Intraocular Lens Research), Storm Eye Institute, Medical University of South CarolinaCharlestonSouth CarolinaUSA</mods:affiliation><wicri:noCountry code="subField">Medical University of South CarolinaCharlestonSouth CarolinaUSA</wicri:noCountry></affiliation></author></analytic><monogr></monogr><series><title level="j">Journal of Cataract & Refractive Surgery</title><title level="j" type="abbrev">JCRS</title><idno type="ISSN">0886-3350</idno><imprint><publisher>ELSEVIER</publisher><date type="published" when="1998">1998</date><biblScope unit="volume">24</biblScope><biblScope unit="issue">5</biblScope><biblScope unit="page" from="666">666</biblScope><biblScope unit="page" to="671">671</biblScope></imprint><idno type="ISSN">0886-3350</idno></series><idno type="istex">5ABA5A942A8EEFA32774542FDF9C3360552E54C8</idno><idno type="DOI">10.1016/S0886-3350(98)80263-0</idno><idno type="PII">S0886-3350(98)80263-0</idno><idno type="ArticleID">80263</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0886-3350</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Purpose: To evaluate the effects of a new mini-haptic design on the strength and stability of capsular bag fixation of plate-haptic silicone intraocular lenses (IOLs) and determine whether this design encourages the growth of regenerating lens material or fibrous tissue around the haptic biomaterial and thus improves lens fixation in the capsular bag.Setting: Center for Research on Ocular Therapeutics and Biodevices, Storm Eye Institute, Medical University of South Carolina, Department of Ophthalmology, Charleston, South Carolina, USA.Methods: Six rabbits had bilateral continuous curvilinear capsulorhexis, phacoemulsification, and plate-haptic silicone IOL implantation. Each rabbit had a small-hole plate IOL (Chiron C10UB) implanted in the right eye and a mini-haptic plate IOL (Chiron C40UB) in the left eye. All rabbits were killed at 2 months. The force required to extract one haptic from the capsular bag was measured with a digital force gauge. Histopathologic analysis was performed on all specimens.Results: The mini-haptic style IOLs required significantly more extraction force than the small-hole design (P = .011). Histopathologically, proliferating lens epithelial cells were observed growing circumferentially around the mini-haptics, causing a 360 degree synechia formation. This formation did not occur with the conventional small-hole plate IOLs used as the control.Conclusions: Lens epithelial cell proliferation around the mini-haptics significantly improved capsular bag fixation of the plate-haptic silicone IOL. This should decrease the incidence of clinical decentration and dislocation.</div></front></TEI></record>Pour manipuler ce document sous Unix (Dilib)
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