A new case of primary signet-ring cell carcinoma of the cervix with prominent endometrial and myometrial involvement: Immunohistochemical and molecular studies and review of the literature
Identifieur interne : 000267 ( Main/Exploration ); précédent : 000266; suivant : 000268A new case of primary signet-ring cell carcinoma of the cervix with prominent endometrial and myometrial involvement: Immunohistochemical and molecular studies and review of the literature
Auteurs : Giovanna Giordano ; Silvia Pizzi ; Roberto Berretta ; Tiziana D'AddaSource :
- World Journal of Surgical Oncology [ 1477-7819 ] ; 2012.
Abstract
As a rule, endocervical tumours with signet-ring cell are classed as metastatic extra-genital neoplasms. In a patient aged 45 years, we describe primary cervical signet-ring cell carcinoma (PCSRCC) characterized by prominent endometrial and myometrial involvement, simulating primary endometrial adenocarcinoma with cervical extension. In addition, a review was made of the literature to identify the clinical and pathological features of this rare malignancy.
A 45-year-old woman was referred to our Gynaecology Department due to persistent abnormal vaginal bleeding. Transvaginal ultrasonography showed slight endometrial irregularities in the whole uterine cavity suggestive of endometrial neoplasms. Pelvic magnetic resonance imaging revealed diffuse enlargement of the cervix, which had been replaced by a mass. Induration extended to the parametria and sigmoid colon fat.
Histological examination of endometrial curettage and a cervical biopsy revealed a neoplasm characterized by neoplastic signet-ring cells and trabecular structures. Immunohistochemical analysis and molecular studies showed certain findings consistent with a cervical neoplasm, such as positivity to CEA, keratin 7, Ca-125 and p16 and the presence of HPV (Human Papilloma Virus) DNA 18.
On examination of the hysterectomy with bilateral salpingo-oophorectomy and pelvic lymphadenectomy, the lesion replacing the cervix, endometrium and myometrium, revealed the same immunohistochemical findings observed on endometrial curettage and cervical biopsy specimens. Metastases were found in an ovarian cystic lesion and the lymph nodes.
With this report the authors have demonstrated that the spread of cervical adenocarcinoma to the uterine corpus, although rare, may be observed, and that in this instance immunohistochemical and molecular studies can provide sufficient information for accurate diagnosis even on small biopsy specimens.
Url:
DOI: 10.1186/1477-7819-10-7
PubMed: 22236794
PubMed Central: 3320546
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 000139
- to stream Pmc, to step Curation: 000139
- to stream Pmc, to step Checkpoint: 000097
- to stream Ncbi, to step Merge: 000163
- to stream Ncbi, to step Curation: 000163
- to stream Ncbi, to step Checkpoint: 000163
- to stream Main, to step Merge: 000262
- to stream Main, to step Curation: 000267
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">A new case of primary signet-ring cell carcinoma of the cervix with prominent endometrial and myometrial involvement: Immunohistochemical and molecular studies and review of the literature</title><author><name sortKey="Giordano, Giovanna" sort="Giordano, Giovanna" uniqKey="Giordano G" first="Giovanna" last="Giordano">Giovanna Giordano</name><affiliation><nlm:aff id="I1">Department of Pathology and Medicine of Laboratory, Section of Pathology, Parma University</nlm:aff><wicri:noCountry code="subfield">Parma University</wicri:noCountry></affiliation></author><author><name sortKey="Pizzi, Silvia" sort="Pizzi, Silvia" uniqKey="Pizzi S" first="Silvia" last="Pizzi">Silvia Pizzi</name><affiliation><nlm:aff id="I1">Department of Pathology and Medicine of Laboratory, Section of Pathology, Parma University</nlm:aff><wicri:noCountry code="subfield">Parma University</wicri:noCountry></affiliation></author><author><name sortKey="Berretta, Roberto" sort="Berretta, Roberto" uniqKey="Berretta R" first="Roberto" last="Berretta">Roberto Berretta</name><affiliation><nlm:aff id="I2">Department of Obstetric and Gynaecologic Sciences and Neonatology, Parma University</nlm:aff><wicri:noCountry code="subfield">Parma University</wicri:noCountry></affiliation></author><author><name sortKey="D Adda, Tiziana" sort="D Adda, Tiziana" uniqKey="D Adda T" first="Tiziana" last="D'Adda">Tiziana D'Adda</name><affiliation><nlm:aff id="I1">Department of Pathology and Medicine of Laboratory, Section of Pathology, Parma University</nlm:aff><wicri:noCountry code="subfield">Parma University</wicri:noCountry></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">22236794</idno><idno type="pmc">3320546</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3320546</idno><idno type="RBID">PMC:3320546</idno><idno type="doi">10.1186/1477-7819-10-7</idno><date when="2012">2012</date><idno type="wicri:Area/Pmc/Corpus">000139</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000139</idno><idno type="wicri:Area/Pmc/Curation">000139</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000139</idno><idno type="wicri:Area/Pmc/Checkpoint">000097</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000097</idno><idno type="wicri:Area/Ncbi/Merge">000163</idno><idno type="wicri:Area/Ncbi/Curation">000163</idno><idno type="wicri:Area/Ncbi/Checkpoint">000163</idno><idno type="wicri:Area/Main/Merge">000262</idno><idno type="wicri:Area/Main/Curation">000267</idno><idno type="wicri:Area/Main/Exploration">000267</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">A new case of primary signet-ring cell carcinoma of the cervix with prominent endometrial and myometrial involvement: Immunohistochemical and molecular studies and review of the literature</title><author><name sortKey="Giordano, Giovanna" sort="Giordano, Giovanna" uniqKey="Giordano G" first="Giovanna" last="Giordano">Giovanna Giordano</name><affiliation><nlm:aff id="I1">Department of Pathology and Medicine of Laboratory, Section of Pathology, Parma University</nlm:aff><wicri:noCountry code="subfield">Parma University</wicri:noCountry></affiliation></author><author><name sortKey="Pizzi, Silvia" sort="Pizzi, Silvia" uniqKey="Pizzi S" first="Silvia" last="Pizzi">Silvia Pizzi</name><affiliation><nlm:aff id="I1">Department of Pathology and Medicine of Laboratory, Section of Pathology, Parma University</nlm:aff><wicri:noCountry code="subfield">Parma University</wicri:noCountry></affiliation></author><author><name sortKey="Berretta, Roberto" sort="Berretta, Roberto" uniqKey="Berretta R" first="Roberto" last="Berretta">Roberto Berretta</name><affiliation><nlm:aff id="I2">Department of Obstetric and Gynaecologic Sciences and Neonatology, Parma University</nlm:aff><wicri:noCountry code="subfield">Parma University</wicri:noCountry></affiliation></author><author><name sortKey="D Adda, Tiziana" sort="D Adda, Tiziana" uniqKey="D Adda T" first="Tiziana" last="D'Adda">Tiziana D'Adda</name><affiliation><nlm:aff id="I1">Department of Pathology and Medicine of Laboratory, Section of Pathology, Parma University</nlm:aff><wicri:noCountry code="subfield">Parma University</wicri:noCountry></affiliation></author></analytic><series><title level="j">World Journal of Surgical Oncology</title><idno type="eISSN">1477-7819</idno><imprint><date when="2012">2012</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec><title>Background</title><p>As a rule, endocervical tumours with signet-ring cell are classed as metastatic extra-genital neoplasms. In a patient aged 45 years, we describe primary cervical signet-ring cell carcinoma (PCSRCC) characterized by prominent endometrial and myometrial involvement, simulating primary endometrial adenocarcinoma with cervical extension. In addition, a review was made of the literature to identify the clinical and pathological features of this rare malignancy.</p></sec><sec><title>Case presentation</title><p>A 45-year-old woman was referred to our Gynaecology Department due to persistent abnormal vaginal bleeding. Transvaginal ultrasonography showed slight endometrial irregularities in the whole uterine cavity suggestive of endometrial neoplasms. Pelvic magnetic resonance imaging revealed diffuse enlargement of the cervix, which had been replaced by a mass. Induration extended to the parametria and sigmoid colon fat.</p><p>Histological examination of endometrial curettage and a cervical biopsy revealed a neoplasm characterized by neoplastic signet-ring cells and trabecular structures. Immunohistochemical analysis and molecular studies showed certain findings consistent with a cervical neoplasm, such as positivity to CEA, keratin 7, Ca-125 and p16 and the presence of HPV (Human Papilloma Virus) DNA 18.</p><p>On examination of the hysterectomy with bilateral salpingo-oophorectomy and pelvic lymphadenectomy, the lesion replacing the cervix, endometrium and myometrium, revealed the same immunohistochemical findings observed on endometrial curettage and cervical biopsy specimens. Metastases were found in an ovarian cystic lesion and the lymph nodes.</p></sec><sec><title>Conclusion</title><p>With this report the authors have demonstrated that the spread of cervical adenocarcinoma to the uterine corpus, although rare, may be observed, and that in this instance immunohistochemical and molecular studies can provide sufficient information for accurate diagnosis even on small biopsy specimens.</p></sec></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="El Zimaity, Hm" uniqKey="El Zimaity H">HM el-Zimaity</name></author><author><name sortKey="Itani, K" uniqKey="Itani K">K Itani</name></author><author><name sortKey="Graham, Dy" uniqKey="Graham D">DY Graham</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Leong, Fj" uniqKey="Leong F">FJ Leong</name></author><author><name sortKey="Leong, As" uniqKey="Leong A">AS Leong</name></author><author><name sortKey="Swift, J" uniqKey="Swift J">J Swift</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jain, V" uniqKey="Jain V">V Jain</name></author><author><name sortKey="Gupta, K" uniqKey="Gupta K">K Gupta</name></author><author><name sortKey="Kudva, R" uniqKey="Kudva R">R Kudva</name></author><author><name sortKey="Rodrigues, Gs" uniqKey="Rodrigues G">GS Rodrigues</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Makino, T" uniqKey="Makino T">T Makino</name></author><author><name sortKey="Tsujinaka, T" uniqKey="Tsujinaka T">T Tsujinaka</name></author><author><name sortKey="Mishima, H" uniqKey="Mishima H">H Mishima</name></author><author><name sortKey="Ikenaga, M" uniqKey="Ikenaga M">M Ikenaga</name></author><author><name sortKey="Sawamura, T" uniqKey="Sawamura T">T Sawamura</name></author><author><name sortKey="Nakamori, S" uniqKey="Nakamori S">S Nakamori</name></author><author><name sortKey="Fujitani, K" uniqKey="Fujitani K">K Fujitani</name></author><author><name sortKey="Hirao, M" uniqKey="Hirao M">M Hirao</name></author><author><name sortKey="Kashiwazaki, M" uniqKey="Kashiwazaki M">M Kashiwazaki</name></author><author><name sortKey="Masuda, N" uniqKey="Masuda N">N Masuda</name></author><author><name sortKey="Takeda, M" uniqKey="Takeda M">M Takeda</name></author><author><name sortKey="Mano, M" uniqKey="Mano M">M Mano</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Michal, M" uniqKey="Michal M">M Michal</name></author><author><name sortKey="Hes, O" uniqKey="Hes O">O Hes</name></author><author><name sortKey="Kazakov, Dv" uniqKey="Kazakov D">DV Kazakov</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chehal, A" uniqKey="Chehal A">A Chehal</name></author><author><name sortKey="Seoud, M" uniqKey="Seoud M">M Seoud</name></author><author><name sortKey="Taher, A" uniqKey="Taher A">A Taher</name></author><author><name sortKey="Salem, N" uniqKey="Salem N">N Salem</name></author><author><name sortKey="Khalil, A" uniqKey="Khalil A">A Khalil</name></author><author><name sortKey="Shamsseddine, A" uniqKey="Shamsseddine A">A Shamsseddine</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kennebeck, Ch" uniqKey="Kennebeck C">CH Kennebeck</name></author><author><name sortKey="Alagoz, T" uniqKey="Alagoz T">T Alagoz</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Giordano, G" uniqKey="Giordano G">G Giordano</name></author><author><name sortKey="Gnetti, L" uniqKey="Gnetti L">L Gnetti</name></author><author><name sortKey="Ricci, R" uniqKey="Ricci R">R Ricci</name></author><author><name sortKey="Merisio, M" uniqKey="Merisio M">M Merisio</name></author><author><name sortKey="Melpignano, M" uniqKey="Melpignano M">M Melpignano</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Giordano, G" uniqKey="Giordano G">G Giordano</name></author><author><name sortKey="Gnetti, L" uniqKey="Gnetti L">L Gnetti</name></author><author><name sortKey="Pilato, Fp" uniqKey="Pilato F">FP Pilato</name></author><author><name sortKey="Viviano, L" uniqKey="Viviano L">L Viviano</name></author><author><name sortKey="Silini, Em" uniqKey="Silini E">EM Silini</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mooney, Ee" uniqKey="Mooney E">EE Mooney</name></author><author><name sortKey="Robboy, Sj" uniqKey="Robboy S">SJ Robboy</name></author><author><name sortKey="Hammond, Cb" uniqKey="Hammond C">CB Hammond</name></author><author><name sortKey="Berchuck, A" uniqKey="Berchuck A">A Berchuck</name></author><author><name sortKey="Bentley, Rc" uniqKey="Bentley R">RC Bentley</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chebib, I" uniqKey="Chebib I">I Chebib</name></author><author><name sortKey="Chu, P" uniqKey="Chu P">P Chu</name></author><author><name sortKey="Duggan, Ma" uniqKey="Duggan M">MA Duggan</name></author><author><name sortKey="Difrancesco, Lm" uniqKey="Difrancesco L">LM DiFrancesco</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Boyd, C" uniqKey="Boyd C">C Boyd</name></author><author><name sortKey="Cameron, I" uniqKey="Cameron I">I Cameron</name></author><author><name sortKey="Mccluggage, Wg" uniqKey="Mccluggage W">WG McCluggage</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Moll, Um" uniqKey="Moll U">UM Moll</name></author><author><name sortKey="Chumas, Jc" uniqKey="Chumas J">JC Chumas</name></author><author><name sortKey="Mann, Wj" uniqKey="Mann W">WJ Mann</name></author><author><name sortKey="Patsner, B" uniqKey="Patsner B">B Patsner</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mayorga, M" uniqKey="Mayorga M">M Mayorga</name></author><author><name sortKey="Garcia Valtuille, A" uniqKey="Garcia Valtuille A">A Garcia-Valtuille</name></author><author><name sortKey="Fernandez, F" uniqKey="Fernandez F">F Fernandez</name></author><author><name sortKey="Val Bernal, Jf" uniqKey="Val Bernal J">JF Val-Bernal</name></author><author><name sortKey="Cabrera, E" uniqKey="Cabrera E">E Cabrera</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Haswani, P" uniqKey="Haswani P">P Haswani</name></author><author><name sortKey="Arseneau, J" uniqKey="Arseneau J">J Arseneau</name></author><author><name sortKey="Ferenczy, A" uniqKey="Ferenczy A">A Ferenczy</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cardosi, Rj" uniqKey="Cardosi R">RJ Cardosi</name></author><author><name sortKey="Reedy, Mb" uniqKey="Reedy M">MB Reedy</name></author><author><name sortKey="Van Nagell, Jr" uniqKey="Van Nagell J">JR Van Nagell</name></author><author><name sortKey="Spires, Se" uniqKey="Spires S">SE Spires</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Moritani, S" uniqKey="Moritani S">S Moritani</name></author><author><name sortKey="Ichihara, S" uniqKey="Ichihara S">S Ichihara</name></author><author><name sortKey="Kushima, R" uniqKey="Kushima R">R Kushima</name></author><author><name sortKey="Sugiura, F" uniqKey="Sugiura F">F Sugiura</name></author><author><name sortKey="Mushika, M" uniqKey="Mushika M">M Mushika</name></author><author><name sortKey="Silverberg, Sg" uniqKey="Silverberg S">SG Silverberg</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Insabato, L" uniqKey="Insabato L">L Insabato</name></author><author><name sortKey="Simonetti, S" uniqKey="Simonetti S">S Simonetti</name></author><author><name sortKey="De Cecio, R" uniqKey="De Cecio R">R De Cecio</name></author><author><name sortKey="Di Tuoro, S" uniqKey="Di Tuoro S">S Di Tuoro</name></author><author><name sortKey="Bifulco, G" uniqKey="Bifulco G">G Bifulco</name></author><author><name sortKey="Di Spiezio Sardo, A" uniqKey="Di Spiezio Sardo A">A Di Spiezio Sardo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Suarez Pe Aranda, Jm" uniqKey="Suarez Pe Aranda J">JM Suárez-Peñaranda</name></author><author><name sortKey="Abdulkader, I" uniqKey="Abdulkader I">I Abdulkader</name></author><author><name sortKey="Bar N Duarte, Fj" uniqKey="Bar N Duarte F">FJ Barón-Duarte</name></author><author><name sortKey="Gonzalez Pati O, E" uniqKey="Gonzalez Pati O E">E González Patiño</name></author><author><name sortKey="Novo Dominguez, A" uniqKey="Novo Dominguez A">A Novo-Domínguez</name></author><author><name sortKey="Varela Duran, J" uniqKey="Varela Duran J">J Varela-Durán</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mccluggage, Wg" uniqKey="Mccluggage W">WG McCluggage</name></author><author><name sortKey="Shah, R" uniqKey="Shah R">R Shah</name></author><author><name sortKey="Connolly, Le" uniqKey="Connolly L">LE Connolly</name></author><author><name sortKey="Mcbride, Ha" uniqKey="Mcbride H">HA McBride</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Veras, E" uniqKey="Veras E">E Veras</name></author><author><name sortKey="Srodon, M" uniqKey="Srodon M">M Srodon</name></author><author><name sortKey="Neijstrom, Es" uniqKey="Neijstrom E">ES Neijstrom</name></author><author><name sortKey="Ronnett, Bm" uniqKey="Ronnett B">BM Ronnett</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Balci, S" uniqKey="Balci S">S Balci</name></author><author><name sortKey="Saglam, A" uniqKey="Saglam A">A Saglam</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="De Roda Husman, Am" uniqKey="De Roda Husman A">AM de Roda Husman</name></author><author><name sortKey="Walboomers, Jm" uniqKey="Walboomers J">JM Walboomers</name></author><author><name sortKey="Van Den Brule, Aj" uniqKey="Van Den Brule A">AJ van den Brule</name></author><author><name sortKey="Meijer, Cj" uniqKey="Meijer C">CJ Meijer</name></author><author><name sortKey="Snijders, Pj" uniqKey="Snijders P">PJ Snijders</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Greer, Ce" uniqKey="Greer C">CE Greer</name></author><author><name sortKey="Peterson, Sl" uniqKey="Peterson S">SL Peterson</name></author><author><name sortKey="Kiviat, Nb" uniqKey="Kiviat N">NB Kiviat</name></author><author><name sortKey="Manos, Mm" uniqKey="Manos M">MM Manos</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kim, Jp" uniqKey="Kim J">JP Kim</name></author><author><name sortKey="Kim, Sc" uniqKey="Kim S">SC Kim</name></author><author><name sortKey="Yang, Hk" uniqKey="Yang H">HK Yang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gompel, C" uniqKey="Gompel C">C Gompel</name></author><author><name sortKey="Silverberg, Sg" uniqKey="Silverberg S">SG Silverberg</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Alguacil Garcia, A" uniqKey="Alguacil Garcia A">A Alguacil-Garcia</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Arista Nasr, J" uniqKey="Arista Nasr J">J Arista-Nasr</name></author><author><name sortKey="Romero Lagarza, P" uniqKey="Romero Lagarza P">P Romero-Lagarza</name></author><author><name sortKey="Pichardo Bahena, R" uniqKey="Pichardo Bahena R">R Pichardo-Bahena</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mccluggage, Wg" uniqKey="Mccluggage W">WG McCluggage</name></author><author><name sortKey="Bharucha, H" uniqKey="Bharucha H">H Bharucha</name></author><author><name sortKey="El Agnaf, M" uniqKey="El Agnaf M">M El-Agnaf</name></author><author><name sortKey="Toner, Pg" uniqKey="Toner P">PG Toner</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Dickersin, Gr" uniqKey="Dickersin G">GR Dickersin</name></author><author><name sortKey="Young, Rh" uniqKey="Young R">RH Young</name></author><author><name sortKey="Scully, Re" uniqKey="Scully R">RE Scully</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kearns, M" uniqKey="Kearns M">M Kearns</name></author><author><name sortKey="Lala, Pk" uniqKey="Lala P">PK Lala</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ledford, Be" uniqKey="Ledford B">BE Ledford</name></author><author><name sortKey="Rankin, Jc" uniqKey="Rankin J">JC Rankin</name></author><author><name sortKey="Markwald, Rr" uniqKey="Markwald R">RR Markwald</name></author><author><name sortKey="Baggett, B" uniqKey="Baggett B">B Baggett</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Monteagudo, C" uniqKey="Monteagudo C">C Monteagudo</name></author><author><name sortKey="Merino, Mj" uniqKey="Merino M">MJ Merino</name></author><author><name sortKey="Laporte, N" uniqKey="Laporte N">N Laporte</name></author><author><name sortKey="Neumann, Rd" uniqKey="Neumann R">RD Neumann</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tenti, P" uniqKey="Tenti P">P Tenti</name></author><author><name sortKey="Romagnoli, S" uniqKey="Romagnoli S">S Romagnoli</name></author><author><name sortKey="Silini, E" uniqKey="Silini E">E Silini</name></author><author><name sortKey="Zappatore, R" uniqKey="Zappatore R">R Zappatore</name></author><author><name sortKey="Giunta, P" uniqKey="Giunta P">P Giunta</name></author><author><name sortKey="Stella, G" uniqKey="Stella G">G Stella</name></author><author><name sortKey="Carnevali, L" uniqKey="Carnevali L">L Carnevali</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pambuccian, Se" uniqKey="Pambuccian S">SE Pambuccian</name></author><author><name sortKey="Bachowski, Gj" uniqKey="Bachowski G">GJ Bachowski</name></author><author><name sortKey="Twiggs, Lb" uniqKey="Twiggs L">LB Twiggs</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sano, T" uniqKey="Sano T">T Sano</name></author><author><name sortKey="Oyama, T" uniqKey="Oyama T">T Oyama</name></author><author><name sortKey="Kashiwabara, K" uniqKey="Kashiwabara K">K Kashiwabara</name></author><author><name sortKey="Fukuda, T" uniqKey="Fukuda T">T Fukuda</name></author><author><name sortKey="Nakajima" uniqKey="Nakajima">Nakajima</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="De Jesus, M" uniqKey="De Jesus M">M de Jesus</name></author><author><name sortKey="Tang, W" uniqKey="Tang W">W Tang</name></author><author><name sortKey="Sadjadi, M" uniqKey="Sadjadi M">M Sadjadi</name></author><author><name sortKey="Belmonte, Ah" uniqKey="Belmonte A">AH Belmonte</name></author><author><name sortKey="Poon, Tp" uniqKey="Poon T">TP Poon</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gungor, T" uniqKey="Gungor T">T Gungor</name></author><author><name sortKey="Altinkaya, So" uniqKey="Altinkaya S">SO Altinkaya</name></author><author><name sortKey="Ozat, M" uniqKey="Ozat M">M Ozat</name></author><author><name sortKey="Akbay, S" uniqKey="Akbay S">S Akbay</name></author><author><name sortKey="Mollamahmutoglu, L" uniqKey="Mollamahmutoglu L">L Mollamahmutoglu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yemelyanova, A" uniqKey="Yemelyanova A">A Yemelyanova</name></author><author><name sortKey="Vang, R" uniqKey="Vang R">R Vang</name></author><author><name sortKey="Seidman, Jd" uniqKey="Seidman J">JD Seidman</name></author><author><name sortKey="Gravitt, Pe" uniqKey="Gravitt P">PE Gravitt</name></author><author><name sortKey="Ronnett, Bm" uniqKey="Ronnett B">BM Ronnett</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mccluggage, Wg" uniqKey="Mccluggage W">WG McCluggage</name></author><author><name sortKey="Jenkins, D" uniqKey="Jenkins D">D Jenkins</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ansari Lari, Ma" uniqKey="Ansari Lari M">MA Ansari-Lari</name></author><author><name sortKey="Staebler, A" uniqKey="Staebler A">A Staebler</name></author><author><name sortKey="Zaino, Rj" uniqKey="Zaino R">RJ Zaino</name></author><author><name sortKey="Shah, Kv" uniqKey="Shah K">KV Shah</name></author><author><name sortKey="Ronnett, Bm" uniqKey="Ronnett B">BM Ronnett</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Giordano, G" uniqKey="Giordano G">G Giordano</name></author><author><name sortKey="D Adda, T" uniqKey="D Adda T">T D'Adda</name></author><author><name sortKey="Gnetti, L" uniqKey="Gnetti L">L Gnetti</name></author><author><name sortKey="Merisio, C" uniqKey="Merisio C">C Merisio</name></author><author><name sortKey="Gabrielli, M" uniqKey="Gabrielli M">M Gabrielli</name></author><author><name sortKey="Melpignano, M" uniqKey="Melpignano M">M Melpignano</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list></list><tree><noCountry><name sortKey="Berretta, Roberto" sort="Berretta, Roberto" uniqKey="Berretta R" first="Roberto" last="Berretta">Roberto Berretta</name><name sortKey="D Adda, Tiziana" sort="D Adda, Tiziana" uniqKey="D Adda T" first="Tiziana" last="D'Adda">Tiziana D'Adda</name><name sortKey="Giordano, Giovanna" sort="Giordano, Giovanna" uniqKey="Giordano G" first="Giovanna" last="Giordano">Giovanna Giordano</name><name sortKey="Pizzi, Silvia" sort="Pizzi, Silvia" uniqKey="Pizzi S" first="Silvia" last="Pizzi">Silvia Pizzi</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Ticri/CIDE/explor/EpistemeV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000267 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000267 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Ticri/CIDE
|area= EpistemeV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= PMC:3320546
|texte= A new case of primary signet-ring cell carcinoma of the cervix with prominent endometrial and myometrial involvement: Immunohistochemical and molecular studies and review of the literature
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:22236794" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a EpistemeV1
| This area was generated with Dilib version V0.6.31. |  |