The informatics core of the Alzheimer's Disease Neuroimaging Initiative
Identifieur interne : 000289 ( Pmc/Curation ); précédent : 000288; suivant : 000290The informatics core of the Alzheimer's Disease Neuroimaging Initiative
Auteurs : Arthur W. Toga ; Karen L. CrawfordSource :
- Alzheimer's & dementia : the journal of the Alzheimer's Association [ 1552-5260 ] ; 2010.
Abstract
The Alzheimer's Diseases Neuroimaging Initiative project has brought together geographically distributed investigators, each collecting data on the progression of Alzheimer's disease. The quantity and diversity of the imaging, clinical, cognitive, biochemical, and genetic data acquired and generated throughout the study necessitated sophisticated informatics systems to organize, manage, and disseminate data and results. We describe, here, a successful and comprehensive system that provides powerful mechanisms for processing, integrating, and disseminating these data not only to support the research needs of the investigators who make up the Alzheimer's Diseases Neuroimaging Initiative cores, but also to provide widespread data access to the greater scientific community for the study of Alzheimer's Disease.
Url:
DOI: 10.1016/j.jalz.2010.03.001
PubMed: 20451873
PubMed Central: 2927123
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<front><journal-meta><journal-id journal-id-type="nlm-journal-id">101231978</journal-id><journal-id journal-id-type="pubmed-jr-id">33173</journal-id><journal-id journal-id-type="nlm-ta">Alzheimers Dement</journal-id><journal-title>Alzheimer's & dementia : the journal of the Alzheimer's Association</journal-title><issn pub-type="ppub">1552-5260</issn><issn pub-type="epub">1552-5279</issn></journal-meta><article-meta><article-id pub-id-type="pmid">20451873</article-id><article-id pub-id-type="pmc">2927123</article-id><article-id pub-id-type="doi">10.1016/j.jalz.2010.03.001</article-id><article-id pub-id-type="manuscript">NIHMS217160</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>The informatics core of the Alzheimer's Disease Neuroimaging Initiative</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Toga</surname><given-names>Arthur W.</given-names></name><xref ref-type="corresp" rid="CR1">*</xref></contrib><contrib contrib-type="author"><name><surname>Crawford</surname><given-names>Karen L.</given-names></name></contrib><contrib contrib-type="author"><collab>Alzheimer's Disease Neuroimaging Initiative</collab></contrib><aff id="A1">Laboratory of Neuro Imaging, Department of Neurology, UCLA School of Medicine, Los Angeles, CA, USA</aff></contrib-group><author-notes><corresp id="CR1"><label>*</label>Corresponding author. Tel.: 310-206-2101; Fax: 310-206-5518. <email>toga@loni.ucla.edu</email></corresp></author-notes><pub-date pub-type="nihms-submitted"><day>1</day><month>7</month><year>2010</year></pub-date><pub-date pub-type="ppub"><month>5</month><year>2010</year></pub-date><pub-date pub-type="pmc-release"><day>24</day><month>8</month><year>2010</year></pub-date><volume>6</volume><issue>3</issue><fpage>247</fpage><lpage>256</lpage><permissions><copyright-statement>© 2010 The Alzheimer's Association. All rights reserved.</copyright-statement><copyright-year>2010</copyright-year></permissions><abstract><p id="P1">The Alzheimer's Diseases Neuroimaging Initiative project has brought together geographically distributed investigators, each collecting data on the progression of Alzheimer's disease. The quantity and diversity of the imaging, clinical, cognitive, biochemical, and genetic data acquired and generated throughout the study necessitated sophisticated informatics systems to organize, manage, and disseminate data and results. We describe, here, a successful and comprehensive system that provides powerful mechanisms for processing, integrating, and disseminating these data not only to support the research needs of the investigators who make up the Alzheimer's Diseases Neuroimaging Initiative cores, but also to provide widespread data access to the greater scientific community for the study of Alzheimer's Disease.</p></abstract><kwd-group><kwd>ADNI</kwd><kwd>Informatics</kwd><kwd>Alzheimer's disease</kwd><kwd>Data management</kwd></kwd-group><contract-num rid="RR1">U54 RR021813-02
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