Assessment and Reconstruction of Novel HSP90 Genes: Duplications, Gains and Losses in Fungal and Animal Lineages
Identifieur interne : 000350 ( Pmc/Checkpoint ); précédent : 000349; suivant : 000351Assessment and Reconstruction of Novel HSP90 Genes: Duplications, Gains and Losses in Fungal and Animal Lineages
Auteurs : Chrysoula N. Pantzartzi [Grèce, République tchèque] ; Elena Drosopoulou [Grèce] ; Zacharias G. Scouras [Grèce]Source :
- PLoS ONE [ 1932-6203 ] ; 2013.
Abstract
Hsp90s, members of the Heat Shock Protein class, protect the structure and function of proteins and play a significant task in cellular homeostasis and signal transduction. In order to determine the number of
Url:
DOI: 10.1371/journal.pone.0073217
PubMed: 24066039
PubMed Central: 3774752
Affiliations:
Links toward previous steps (curation, corpus...)
Links to Exploration step
PMC:3774752Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Assessment and Reconstruction of Novel HSP90 Genes: Duplications, Gains and Losses in Fungal and Animal Lineages</title><author><name sortKey="Pantzartzi, Chrysoula N" sort="Pantzartzi, Chrysoula N" uniqKey="Pantzartzi C" first="Chrysoula N." last="Pantzartzi">Chrysoula N. Pantzartzi</name><affiliation wicri:level="1"><nlm:aff id="aff1"><addr-line>Department of Genetics, Development and Molecular Biology, School of Biology, Faculty of Sciences, Aristotle University of Thessaloniki, Thessaloniki, Greece</addr-line></nlm:aff><country xml:lang="fr">Grèce</country><wicri:regionArea>Department of Genetics, Development and Molecular Biology, School of Biology, Faculty of Sciences, Aristotle University of Thessaloniki, Thessaloniki</wicri:regionArea><wicri:noRegion>Thessaloniki</wicri:noRegion></affiliation><affiliation wicri:level="3"><nlm:aff id="aff2"><addr-line>Department of Transcriptional Regulation, Institute of Molecular Genetics, Prague, Czech Republic</addr-line></nlm:aff><country xml:lang="fr">République tchèque</country><wicri:regionArea>Department of Transcriptional Regulation, Institute of Molecular Genetics, Prague</wicri:regionArea><placeName><settlement type="city">Prague</settlement><region type="région" nuts="2">Bohême centrale</region></placeName></affiliation></author><author><name sortKey="Drosopoulou, Elena" sort="Drosopoulou, Elena" uniqKey="Drosopoulou E" first="Elena" last="Drosopoulou">Elena Drosopoulou</name><affiliation wicri:level="1"><nlm:aff id="aff1"><addr-line>Department of Genetics, Development and Molecular Biology, School of Biology, Faculty of Sciences, Aristotle University of Thessaloniki, Thessaloniki, Greece</addr-line></nlm:aff><country xml:lang="fr">Grèce</country><wicri:regionArea>Department of Genetics, Development and Molecular Biology, School of Biology, Faculty of Sciences, Aristotle University of Thessaloniki, Thessaloniki</wicri:regionArea><wicri:noRegion>Thessaloniki</wicri:noRegion></affiliation></author><author><name sortKey="Scouras, Zacharias G" sort="Scouras, Zacharias G" uniqKey="Scouras Z" first="Zacharias G." last="Scouras">Zacharias G. Scouras</name><affiliation wicri:level="1"><nlm:aff id="aff1"><addr-line>Department of Genetics, Development and Molecular Biology, School of Biology, Faculty of Sciences, Aristotle University of Thessaloniki, Thessaloniki, Greece</addr-line></nlm:aff><country xml:lang="fr">Grèce</country><wicri:regionArea>Department of Genetics, Development and Molecular Biology, School of Biology, Faculty of Sciences, Aristotle University of Thessaloniki, Thessaloniki</wicri:regionArea><wicri:noRegion>Thessaloniki</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">24066039</idno><idno type="pmc">3774752</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774752</idno><idno type="RBID">PMC:3774752</idno><idno type="doi">10.1371/journal.pone.0073217</idno><date when="2013">2013</date><idno type="wicri:Area/Pmc/Corpus">000626</idno><idno type="wicri:Area/Pmc/Curation">000626</idno><idno type="wicri:Area/Pmc/Checkpoint">000350</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Assessment and Reconstruction of Novel HSP90 Genes: Duplications, Gains and Losses in Fungal and Animal Lineages</title><author><name sortKey="Pantzartzi, Chrysoula N" sort="Pantzartzi, Chrysoula N" uniqKey="Pantzartzi C" first="Chrysoula N." last="Pantzartzi">Chrysoula N. Pantzartzi</name><affiliation wicri:level="1"><nlm:aff id="aff1"><addr-line>Department of Genetics, Development and Molecular Biology, School of Biology, Faculty of Sciences, Aristotle University of Thessaloniki, Thessaloniki, Greece</addr-line></nlm:aff><country xml:lang="fr">Grèce</country><wicri:regionArea>Department of Genetics, Development and Molecular Biology, School of Biology, Faculty of Sciences, Aristotle University of Thessaloniki, Thessaloniki</wicri:regionArea><wicri:noRegion>Thessaloniki</wicri:noRegion></affiliation><affiliation wicri:level="3"><nlm:aff id="aff2"><addr-line>Department of Transcriptional Regulation, Institute of Molecular Genetics, Prague, Czech Republic</addr-line></nlm:aff><country xml:lang="fr">République tchèque</country><wicri:regionArea>Department of Transcriptional Regulation, Institute of Molecular Genetics, Prague</wicri:regionArea><placeName><settlement type="city">Prague</settlement><region type="région" nuts="2">Bohême centrale</region></placeName></affiliation></author><author><name sortKey="Drosopoulou, Elena" sort="Drosopoulou, Elena" uniqKey="Drosopoulou E" first="Elena" last="Drosopoulou">Elena Drosopoulou</name><affiliation wicri:level="1"><nlm:aff id="aff1"><addr-line>Department of Genetics, Development and Molecular Biology, School of Biology, Faculty of Sciences, Aristotle University of Thessaloniki, Thessaloniki, Greece</addr-line></nlm:aff><country xml:lang="fr">Grèce</country><wicri:regionArea>Department of Genetics, Development and Molecular Biology, School of Biology, Faculty of Sciences, Aristotle University of Thessaloniki, Thessaloniki</wicri:regionArea><wicri:noRegion>Thessaloniki</wicri:noRegion></affiliation></author><author><name sortKey="Scouras, Zacharias G" sort="Scouras, Zacharias G" uniqKey="Scouras Z" first="Zacharias G." last="Scouras">Zacharias G. Scouras</name><affiliation wicri:level="1"><nlm:aff id="aff1"><addr-line>Department of Genetics, Development and Molecular Biology, School of Biology, Faculty of Sciences, Aristotle University of Thessaloniki, Thessaloniki, Greece</addr-line></nlm:aff><country xml:lang="fr">Grèce</country><wicri:regionArea>Department of Genetics, Development and Molecular Biology, School of Biology, Faculty of Sciences, Aristotle University of Thessaloniki, Thessaloniki</wicri:regionArea><wicri:noRegion>Thessaloniki</wicri:noRegion></affiliation></author></analytic><series><title level="j">PLoS ONE</title><idno type="eISSN">1932-6203</idno><imprint><date when="2013">2013</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Hsp90s, members of the Heat Shock Protein class, protect the structure and function of proteins and play a significant task in cellular homeostasis and signal transduction. In order to determine the number of <italic>hsp90</italic> gene copies and encoded proteins in fungal and animal lineages and through that key duplication events that this family has undergone, we collected and evaluated Hsp90 protein sequences and corresponding Expressed Sequence Tags and analyzed available genomes from various taxa. We provide evidence for duplication events affecting either single species or wider taxonomic groups. With regard to Fungi, duplicated genes have been detected in several lineages. In invertebrates, we demonstrate key duplication events in certain clades of Arthropoda and Mollusca, and a possible gene loss event in a hymenopteran family. Finally, we infer that the duplication event responsible for the two (a and b) isoforms in vertebrates occurred probably shortly after the split of Hyperoartia and Gnathostomata.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Schmitt, E" uniqKey="Schmitt E">E Schmitt</name></author><author><name sortKey="Gehrmann, M" uniqKey="Gehrmann M">M Gehrmann</name></author><author><name sortKey="Brunet, M" uniqKey="Brunet M">M Brunet</name></author><author><name sortKey="Multhoff, G" uniqKey="Multhoff G">G Multhoff</name></author><author><name sortKey="Garrido, C" uniqKey="Garrido C">C Garrido</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hofmann, Ge" uniqKey="Hofmann G">GE Hofmann</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Verghese, J" uniqKey="Verghese J">J Verghese</name></author><author><name sortKey="Abrams, J" uniqKey="Abrams J">J Abrams</name></author><author><name sortKey="Wang, Y" uniqKey="Wang Y">Y Wang</name></author><author><name sortKey="Morano, Ka" uniqKey="Morano K">KA Morano</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Zuehlke, A" uniqKey="Zuehlke A">A Zuehlke</name></author><author><name sortKey="Johnson, Jl" uniqKey="Johnson J">JL Johnson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pearl, Lh" uniqKey="Pearl L">LH Pearl</name></author><author><name sortKey="Prodromou, C" uniqKey="Prodromou C">C Prodromou</name></author><author><name sortKey="Workman, P" uniqKey="Workman P">P Workman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hartson, Sd" uniqKey="Hartson S">SD Hartson</name></author><author><name sortKey="Matts, Rl" uniqKey="Matts R">RL Matts</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Echeverri A, Pc" uniqKey="Echeverri A P">PC Echeverría</name></author><author><name sortKey="Bernthaler, A" uniqKey="Bernthaler A">A Bernthaler</name></author><author><name sortKey="Dupuis, P" uniqKey="Dupuis P">P Dupuis</name></author><author><name sortKey="Mayer, B" uniqKey="Mayer B">B Mayer</name></author><author><name sortKey="Picard, D" uniqKey="Picard D">D Picard</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Brown, Ma" uniqKey="Brown M">MA Brown</name></author><author><name sortKey="Zhu, L" uniqKey="Zhu L">L Zhu</name></author><author><name sortKey="Schmidt, C" uniqKey="Schmidt C">C Schmidt</name></author><author><name sortKey="Tucker, Pw" uniqKey="Tucker P">PW Tucker</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Whitesell, L" uniqKey="Whitesell L">L Whitesell</name></author><author><name sortKey="Lindquist, Sl" uniqKey="Lindquist S">SL Lindquist</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Trepel, J" uniqKey="Trepel J">J Trepel</name></author><author><name sortKey="Mollapour, M" uniqKey="Mollapour M">M Mollapour</name></author><author><name sortKey="Giaccone, G" uniqKey="Giaccone G">G Giaccone</name></author><author><name sortKey="Neckers, L" uniqKey="Neckers L">L Neckers</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bardwell, Jc" uniqKey="Bardwell J">JC Bardwell</name></author><author><name sortKey="Craig, Ea" uniqKey="Craig E">EA Craig</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Versteeg, S" uniqKey="Versteeg S">S Versteeg</name></author><author><name sortKey="Mogk, A" uniqKey="Mogk A">A Mogk</name></author><author><name sortKey="Schumann, W" uniqKey="Schumann W">W Schumann</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Laksanalamai, P" uniqKey="Laksanalamai P">P Laksanalamai</name></author><author><name sortKey="Whitehead, Ta" uniqKey="Whitehead T">TA Whitehead</name></author><author><name sortKey="Robb, Ft" uniqKey="Robb F">FT Robb</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gupta, Rs" uniqKey="Gupta R">RS Gupta</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Csermely, P" uniqKey="Csermely P">P Csermely</name></author><author><name sortKey="Schnaider, T" uniqKey="Schnaider T">T Schnaider</name></author><author><name sortKey="Soti, C" uniqKey="Soti C">C Soti</name></author><author><name sortKey="Prohaszka, Z" uniqKey="Prohaszka Z">Z Prohászka</name></author><author><name sortKey="Nardai, G" uniqKey="Nardai G">G Nardai</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Emelyanov, Vv" uniqKey="Emelyanov V">VV Emelyanov</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chen, B" uniqKey="Chen B">B Chen</name></author><author><name sortKey="Zhong, D" uniqKey="Zhong D">D Zhong</name></author><author><name sortKey="Monteiro, A" uniqKey="Monteiro A">A Monteiro</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chen, B" uniqKey="Chen B">B Chen</name></author><author><name sortKey="Piel, Wh" uniqKey="Piel W">WH Piel</name></author><author><name sortKey="Gui, L" uniqKey="Gui L">L Gui</name></author><author><name sortKey="Bruford, E" uniqKey="Bruford E">E Bruford</name></author><author><name sortKey="Monteiro, A" uniqKey="Monteiro A">A Monteiro</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Moore, Sk" uniqKey="Moore S">SK Moore</name></author><author><name sortKey="Kozak, C" uniqKey="Kozak C">C Kozak</name></author><author><name sortKey="Robinson, Ea" uniqKey="Robinson E">EA Robinson</name></author><author><name sortKey="Ullrich, Sj" uniqKey="Ullrich S">SJ Ullrich</name></author><author><name sortKey="Appella, E" uniqKey="Appella E">E Appella</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Krone, Ph" uniqKey="Krone P">PH Krone</name></author><author><name sortKey="Sass, Jb" uniqKey="Sass J">JB Sass</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Konstantopoulou, I" uniqKey="Konstantopoulou I">I Konstantopoulou</name></author><author><name sortKey="Scouras, Zg" uniqKey="Scouras Z">ZG Scouras</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Birnby, Da" uniqKey="Birnby D">DA Birnby</name></author><author><name sortKey="Link, Em" uniqKey="Link E">EM Link</name></author><author><name sortKey="Vowels, Jj" uniqKey="Vowels J">JJ Vowels</name></author><author><name sortKey="Tian, H" uniqKey="Tian H">H Tian</name></author><author><name sortKey="Colacurcio, Pl" uniqKey="Colacurcio P">PL Colacurcio</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Inoue, T" uniqKey="Inoue T">T Inoue</name></author><author><name sortKey="Takamura, K" uniqKey="Takamura K">K Takamura</name></author><author><name sortKey="Yamae, H" uniqKey="Yamae H">H Yamae</name></author><author><name sortKey="Ise, N" uniqKey="Ise N">N Ise</name></author><author><name sortKey="Kawakami, M" uniqKey="Kawakami M">M Kawakami</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Thompson, Fj" uniqKey="Thompson F">FJ Thompson</name></author><author><name sortKey="Cockroft, Ac" uniqKey="Cockroft A">AC Cockroft</name></author><author><name sortKey="Wheatley, I" uniqKey="Wheatley I">I Wheatley</name></author><author><name sortKey="Britton, C" uniqKey="Britton C">C Britton</name></author><author><name sortKey="Devaney, E" uniqKey="Devaney E">E Devaney</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Benedict, Mq" uniqKey="Benedict M">MQ Benedict</name></author><author><name sortKey="Levine, Bj" uniqKey="Levine B">BJ Levine</name></author><author><name sortKey="Ke, Zx" uniqKey="Ke Z">ZX Ke</name></author><author><name sortKey="Cockburn, Af" uniqKey="Cockburn A">AF Cockburn</name></author><author><name sortKey="Seawright, Ja" uniqKey="Seawright J">JA Seawright</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pantzartzi, Cn" uniqKey="Pantzartzi C">CN Pantzartzi</name></author><author><name sortKey="Kourtidis, A" uniqKey="Kourtidis A">A Kourtidis</name></author><author><name sortKey="Drosopoulou, E" uniqKey="Drosopoulou E">E Drosopoulou</name></author><author><name sortKey="Yiangou, M" uniqKey="Yiangou M">M Yiangou</name></author><author><name sortKey="Scouras, Zg" uniqKey="Scouras Z">ZG Scouras</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zhang, Xy" uniqKey="Zhang X">XY Zhang</name></author><author><name sortKey="Zhang, Mz" uniqKey="Zhang M">MZ Zhang</name></author><author><name sortKey="Zheng, Cj" uniqKey="Zheng C">CJ Zheng</name></author><author><name sortKey="Liu, J" uniqKey="Liu J">J Liu</name></author><author><name sortKey="Hu, Hj" uniqKey="Hu H">HJ Hu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Minchiotti, G" uniqKey="Minchiotti G">G Minchiotti</name></author><author><name sortKey="Gargano, S" uniqKey="Gargano S">S Gargano</name></author><author><name sortKey="Maresca, B" uniqKey="Maresca B">B Maresca</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Swoboda, Rk" uniqKey="Swoboda R">RK Swoboda</name></author><author><name sortKey="Bertram, G" uniqKey="Bertram G">G Bertram</name></author><author><name sortKey="Budge, S" uniqKey="Budge S">S Budge</name></author><author><name sortKey="Gooday, Gw" uniqKey="Gooday G">GW Gooday</name></author><author><name sortKey="Gow, Nar" uniqKey="Gow N">NAR Gow</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pugliese, L" uniqKey="Pugliese L">L Pugliese</name></author><author><name sortKey="Georg, Rc" uniqKey="Georg R">RC Georg</name></author><author><name sortKey="Fietto, Lg" uniqKey="Fietto L">LG Fietto</name></author><author><name sortKey="Gomes, Sl" uniqKey="Gomes S">SL Gomes</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Farrelly, Fw" uniqKey="Farrelly F">FW Farrelly</name></author><author><name sortKey="Finkelstein, Db" uniqKey="Finkelstein D">DB Finkelstein</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Erkine, Am" uniqKey="Erkine A">AM Erkine</name></author><author><name sortKey="Adams, Cc" uniqKey="Adams C">CC Adams</name></author><author><name sortKey="Gao, M" uniqKey="Gao M">M Gao</name></author><author><name sortKey="Gross, Ds" uniqKey="Gross D">DS Gross</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Erkine, Am" uniqKey="Erkine A">AM Erkine</name></author><author><name sortKey="Magrogan, Sf" uniqKey="Magrogan S">SF Magrogan</name></author><author><name sortKey="Sekinger, Ea" uniqKey="Sekinger E">EA Sekinger</name></author><author><name sortKey="Gross, Ds" uniqKey="Gross D">DS Gross</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Bergthorsson, U" uniqKey="Bergthorsson U">U Bergthorsson</name></author><author><name sortKey="Andersson, Di" uniqKey="Andersson D">DI Andersson</name></author><author><name sortKey="Roth, Jr" uniqKey="Roth J">JR Roth</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gao, Q" uniqKey="Gao Q">Q Gao</name></author><author><name sortKey="Zhao, J" uniqKey="Zhao J">J Zhao</name></author><author><name sortKey="Song, L" uniqKey="Song L">L Song</name></author><author><name sortKey="Qiu, L" uniqKey="Qiu L">L Qiu</name></author><author><name sortKey="Yu, Y" uniqKey="Yu Y">Y Yu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gao, Q" uniqKey="Gao Q">Q Gao</name></author><author><name sortKey="Song, L" uniqKey="Song L">L Song</name></author><author><name sortKey="Ni, D" uniqKey="Ni D">D Ni</name></author><author><name sortKey="Wu, L" uniqKey="Wu L">L Wu</name></author><author><name sortKey="Zhang, H" uniqKey="Zhang H">H Zhang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wu, Lt" uniqKey="Wu L">LT Wu</name></author><author><name sortKey="Chu, Kh" uniqKey="Chu K">KH Chu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Echeverri A, Pc" uniqKey="Echeverri A P">PC Echeverrí a</name></author><author><name sortKey="Matrajt, M" uniqKey="Matrajt M">M Matrajt</name></author><author><name sortKey="Harb, Os" uniqKey="Harb O">OS Harb</name></author><author><name sortKey="Zappia, Mp" uniqKey="Zappia M">MP Zappia</name></author><author><name sortKey="Costas, Ma" uniqKey="Costas M">MA Costas</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gupta, Rs" uniqKey="Gupta R">RS Gupta</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Stechmann, A" uniqKey="Stechmann A">A Stechmann</name></author><author><name sortKey="Cavalier Smith, T" uniqKey="Cavalier Smith T">T Cavalier-Smith</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Stechmann, A" uniqKey="Stechmann A">A Stechmann</name></author><author><name sortKey="Cavalier Smith, T" uniqKey="Cavalier Smith T">T Cavalier-Smith</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Magrane, M" uniqKey="Magrane M">M Magrane</name></author><author><name sortKey="Consortium, U" uniqKey="Consortium U">U Consortium</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Galperin, My" uniqKey="Galperin M">MY Galperin</name></author><author><name sortKey="Fernandez Suarez, Xm" uniqKey="Fernandez Suarez X">XM Fernández-Suárez</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sigrist, Cja" uniqKey="Sigrist C">CJA Sigrist</name></author><author><name sortKey="Cerutti, L" uniqKey="Cerutti L">L Cerutti</name></author><author><name sortKey="De Castro, E" uniqKey="De Castro E">E de Castro</name></author><author><name sortKey="Langendijk Genevaux, Ps" uniqKey="Langendijk Genevaux P">PS Langendijk-Genevaux</name></author><author><name sortKey="Bulliard, V" uniqKey="Bulliard V">V Bulliard</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Suen, G" uniqKey="Suen G">G Suen</name></author><author><name sortKey="Teiling, C" uniqKey="Teiling C">C Teiling</name></author><author><name sortKey="Li, L" uniqKey="Li L">L Li</name></author><author><name sortKey="Holt, C" uniqKey="Holt C">C Holt</name></author><author><name sortKey="Abouheif, E" uniqKey="Abouheif E">E Abouheif</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gauthier, J" uniqKey="Gauthier J">J Gauthier</name></author><author><name sortKey="Legeai, F" uniqKey="Legeai F">F Legeai</name></author><author><name sortKey="Zasadzinski, A" uniqKey="Zasadzinski A">A Zasadzinski</name></author><author><name sortKey="Rispe, C" uniqKey="Rispe C">C Rispe</name></author><author><name sortKey="Tagu, D" uniqKey="Tagu D">D Tagu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lawson, D" uniqKey="Lawson D">D Lawson</name></author><author><name sortKey="Arensburger, P" uniqKey="Arensburger P">P Arensburger</name></author><author><name sortKey="Atkinson, P" uniqKey="Atkinson P">P Atkinson</name></author><author><name sortKey="Besansky, Nj" uniqKey="Besansky N">NJ Besansky</name></author><author><name sortKey="Bruggner, Rv" uniqKey="Bruggner R">RV Bruggner</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kersey, Pj" uniqKey="Kersey P">PJ Kersey</name></author><author><name sortKey="Staines, Dm" uniqKey="Staines D">DM Staines</name></author><author><name sortKey="Lawson, D" uniqKey="Lawson D">D Lawson</name></author><author><name sortKey="Kulesha, E" uniqKey="Kulesha E">E Kulesha</name></author><author><name sortKey="Derwent, P" uniqKey="Derwent P">P Derwent</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Benson, Da" uniqKey="Benson D">DA Benson</name></author><author><name sortKey="Karsch Mizrachi, I" uniqKey="Karsch Mizrachi I">I Karsch-Mizrachi</name></author><author><name sortKey="Clark, K" uniqKey="Clark K">K Clark</name></author><author><name sortKey="Lipman, Dj" uniqKey="Lipman D">DJ Lipman</name></author><author><name sortKey="Ostell, J" uniqKey="Ostell J">J Ostell</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Grigoriev, Iv" uniqKey="Grigoriev I">IV Grigoriev</name></author><author><name sortKey="Nordberg, H" uniqKey="Nordberg H">H Nordberg</name></author><author><name sortKey="Shabalov, I" uniqKey="Shabalov I">I Shabalov</name></author><author><name sortKey="Aerts, A" uniqKey="Aerts A">A Aerts</name></author><author><name sortKey="Cantor, M" uniqKey="Cantor M">M Cantor</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Altschul, Sf" uniqKey="Altschul S">SF Altschul</name></author><author><name sortKey="Gish, W" uniqKey="Gish W">W Gish</name></author><author><name sortKey="Miller, W" uniqKey="Miller W">W Miller</name></author><author><name sortKey="Myers, Ew" uniqKey="Myers E">EW Myers</name></author><author><name sortKey="Lipman, Dj" uniqKey="Lipman D">DJ Lipman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Burge, C" uniqKey="Burge C">C Burge</name></author><author><name sortKey="Karlin, S" uniqKey="Karlin S">S Karlin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rogozin, Ib" uniqKey="Rogozin I">IB Rogozin</name></author><author><name sortKey="Milanesi, L" uniqKey="Milanesi L">L Milanesi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Goujon, M" uniqKey="Goujon M">M Goujon</name></author><author><name sortKey="Mcwilliam, H" uniqKey="Mcwilliam H">H McWilliam</name></author><author><name sortKey="Li, W" uniqKey="Li W">W Li</name></author><author><name sortKey="Valentin, F" uniqKey="Valentin F">F Valentin</name></author><author><name sortKey="Squizzato, S" uniqKey="Squizzato S">S Squizzato</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rice, P" uniqKey="Rice P">P Rice</name></author><author><name sortKey="Longden, I" uniqKey="Longden I">I Longden</name></author><author><name sortKey="Bleasby, A" uniqKey="Bleasby A">A Bleasby</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Thompson, Jd" uniqKey="Thompson J">JD Thompson</name></author><author><name sortKey="Higgins, Dg" uniqKey="Higgins D">DG Higgins</name></author><author><name sortKey="Gibson, Tj" uniqKey="Gibson T">TJ Gibson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ronquist, F" uniqKey="Ronquist F">F Ronquist</name></author><author><name sortKey="Huelsenbeck, Jp" uniqKey="Huelsenbeck J">JP Huelsenbeck</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Tamura, K" uniqKey="Tamura K">K Tamura</name></author><author><name sortKey="Peterson, D" uniqKey="Peterson D">D Peterson</name></author><author><name sortKey="Peterson, N" uniqKey="Peterson N">N Peterson</name></author><author><name sortKey="Stecher, G" uniqKey="Stecher G">G Stecher</name></author><author><name sortKey="Nei, M" uniqKey="Nei M">M Nei</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Felsenstein, J" uniqKey="Felsenstein J">J Felsenstein</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Felsenstein, J" uniqKey="Felsenstein J">J Felsenstein</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Nakao, Y" uniqKey="Nakao Y">Y Nakao</name></author><author><name sortKey="Kanamori, T" uniqKey="Kanamori T">T Kanamori</name></author><author><name sortKey="Itoh, T" uniqKey="Itoh T">T Itoh</name></author><author><name sortKey="Kodama, Y" uniqKey="Kodama Y">Y Kodama</name></author><author><name sortKey="Rainieri, S" uniqKey="Rainieri S">S Rainieri</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Langkj R, Rb" uniqKey="Langkj R R">RB Langkjær</name></author><author><name sortKey="Cliften, Pf" uniqKey="Cliften P">PF Cliften</name></author><author><name sortKey="Johnston, M" uniqKey="Johnston M">M Johnston</name></author><author><name sortKey="Piskur, J" uniqKey="Piskur J">J Piškur</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kellis, M" uniqKey="Kellis M">M Kellis</name></author><author><name sortKey="Birren, Bw" uniqKey="Birren B">BW Birren</name></author><author><name sortKey="Lander, Es" uniqKey="Lander E">ES Lander</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Van Hoek, Mja" uniqKey="Van Hoek M">MJA Van Hoek</name></author><author><name sortKey="Hogeweg, P" uniqKey="Hogeweg P">P Hogeweg</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wolfe, Kh" uniqKey="Wolfe K">KH Wolfe</name></author><author><name sortKey="Shields, Dc" uniqKey="Shields D">DC Shields</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Nardi, T" uniqKey="Nardi T">T Nardi</name></author><author><name sortKey="Remize, F" uniqKey="Remize F">F Remize</name></author><author><name sortKey="Alexandre, H" uniqKey="Alexandre H">H Alexandre</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wapinski, I" uniqKey="Wapinski I">I Wapinski</name></author><author><name sortKey="Pfeffer, A" uniqKey="Pfeffer A">A Pfeffer</name></author><author><name sortKey="Friedman, N" uniqKey="Friedman N">N Friedman</name></author><author><name sortKey="Regev, A" uniqKey="Regev A">A Regev</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ma, Lj" uniqKey="Ma L">LJ Ma</name></author><author><name sortKey="Ibrahim, As" uniqKey="Ibrahim A">AS Ibrahim</name></author><author><name sortKey="Skory, C" uniqKey="Skory C">C Skory</name></author><author><name sortKey="Grabherr, Mg" uniqKey="Grabherr M">MG Grabherr</name></author><author><name sortKey="Burger, G" uniqKey="Burger G">G Burger</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Xu, Pj" uniqKey="Xu P">PJ Xu</name></author><author><name sortKey="Xiao, Jh" uniqKey="Xiao J">JH Xiao</name></author><author><name sortKey="Xia, Qy" uniqKey="Xia Q">QY Xia</name></author><author><name sortKey="Murphy, B" uniqKey="Murphy B">B Murphy</name></author><author><name sortKey="Huang, Dw" uniqKey="Huang D">DW Huang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zhao, L" uniqKey="Zhao L">L Zhao</name></author><author><name sortKey="Jones, Wa" uniqKey="Jones W">WA Jones</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Benoit, Jb" uniqKey="Benoit J">JB Benoit</name></author><author><name sortKey="Lopez Martinez, G" uniqKey="Lopez Martinez G">G Lopez-Martinez</name></author><author><name sortKey="Phillips, Zp" uniqKey="Phillips Z">ZP Phillips</name></author><author><name sortKey="Patrick, Kr" uniqKey="Patrick K">KR Patrick</name></author><author><name sortKey="Denlinger, Dl" uniqKey="Denlinger D">DL Denlinger</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sinclair, Bj" uniqKey="Sinclair B">BJ Sinclair</name></author><author><name sortKey="Gibbs, Ag" uniqKey="Gibbs A">AG Gibbs</name></author><author><name sortKey="Roberts, Sp" uniqKey="Roberts S">SP Roberts</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Spassky, B" uniqKey="Spassky B">B Spassky</name></author><author><name sortKey="Richmond, Rc" uniqKey="Richmond R">RC Richmond</name></author><author><name sortKey="Perez Salas, S" uniqKey="Perez Salas S">S Pérez-Salas</name></author><author><name sortKey="Pavlovsky, O" uniqKey="Pavlovsky O">O Pavlovsky</name></author><author><name sortKey="Mourao, Ca" uniqKey="Mourao C">CA Mourão</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Parsons, Pa" uniqKey="Parsons P">PA Parsons</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Aamodt, Rm" uniqKey="Aamodt R">RM Aamodt</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wheeler, De" uniqKey="Wheeler D">DE Wheeler</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Suarez, Av" uniqKey="Suarez A">AV Suarez</name></author><author><name sortKey="Holway, Da" uniqKey="Holway D">DA Holway</name></author><author><name sortKey="Case, Tj" uniqKey="Case T">TJ Case</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Smith, Cd" uniqKey="Smith C">CD Smith</name></author><author><name sortKey="Zimin, A" uniqKey="Zimin A">A Zimin</name></author><author><name sortKey="Holt, C" uniqKey="Holt C">C Holt</name></author><author><name sortKey="Abouheif, E" uniqKey="Abouheif E">E Abouheif</name></author><author><name sortKey="Benton, R" uniqKey="Benton R">R Benton</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Long, M" uniqKey="Long M">M Long</name></author><author><name sortKey="Betran, E" uniqKey="Betran E">E Betrán</name></author><author><name sortKey="Thornton, K" uniqKey="Thornton K">K Thornton</name></author><author><name sortKey="Wang, W" uniqKey="Wang W">W Wang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kidwell, Mg" uniqKey="Kidwell M">MG Kidwell</name></author><author><name sortKey="Lisch, Dr" uniqKey="Lisch D">DR Lisch</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kidwell, Mg" uniqKey="Kidwell M">MG Kidwell</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Quesneville, H" uniqKey="Quesneville H">H Quesneville</name></author><author><name sortKey="Bergman, Cm" uniqKey="Bergman C">CM Bergman</name></author><author><name sortKey="Andrieu, O" uniqKey="Andrieu O">O Andrieu</name></author><author><name sortKey="Autard, D" uniqKey="Autard D">D Autard</name></author><author><name sortKey="Nouaud, D" uniqKey="Nouaud D">D Nouaud</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sassi, Ak" uniqKey="Sassi A">AK Sassi</name></author><author><name sortKey="Heredia, F" uniqKey="Heredia F">F Herédia</name></author><author><name sortKey="Loreto, El" uniqKey="Loreto E">EL Loreto</name></author><author><name sortKey="Valente, Vl" uniqKey="Valente V">VL Valente</name></author><author><name sortKey="Rohde, C" uniqKey="Rohde C">C Rohde</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Clark, Ag" uniqKey="Clark A">AG Clark</name></author><author><name sortKey="Eisen, Mb" uniqKey="Eisen M">MB Eisen</name></author><author><name sortKey="Smith, Dr" uniqKey="Smith D">DR Smith</name></author><author><name sortKey="Bergman, Cm" uniqKey="Bergman C">CM Bergman</name></author><author><name sortKey="Oliver, B" uniqKey="Oliver B">B Oliver</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zdobnov, Em" uniqKey="Zdobnov E">EM Zdobnov</name></author><author><name sortKey="Von Mering, C" uniqKey="Von Mering C">C Von Mering</name></author><author><name sortKey="Letunic, I" uniqKey="Letunic I">I Letunic</name></author><author><name sortKey="Torrents, D" uniqKey="Torrents D">D Torrents</name></author><author><name sortKey="Suyama, M" uniqKey="Suyama M">M Suyama</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Holt, Ra" uniqKey="Holt R">RA Holt</name></author><author><name sortKey="Subramanian, Mg" uniqKey="Subramanian M">MG Subramanian</name></author><author><name sortKey="Halpern, A" uniqKey="Halpern A">A Halpern</name></author><author><name sortKey="Sutton, Gg" uniqKey="Sutton G">GG Sutton</name></author><author><name sortKey="Charlab, R" uniqKey="Charlab R">R Charlab</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Nene, V" uniqKey="Nene V">V Nene</name></author><author><name sortKey="Wortman, Jr" uniqKey="Wortman J">JR Wortman</name></author><author><name sortKey="Lawson, D" uniqKey="Lawson D">D Lawson</name></author><author><name sortKey="Haas, B" uniqKey="Haas B">B Haas</name></author><author><name sortKey="Kodira, C" uniqKey="Kodira C">C Kodira</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Yoshida, Ma" uniqKey="Yoshida M">MA Yoshida</name></author><author><name sortKey="Ishikura, Y" uniqKey="Ishikura Y">Y Ishikura</name></author><author><name sortKey="Moritaki, T" uniqKey="Moritaki T">T Moritaki</name></author><author><name sortKey="Shoguchi, E" uniqKey="Shoguchi E">E Shoguchi</name></author><author><name sortKey="Shimizu, Kk" uniqKey="Shimizu K">KK Shimizu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Van De Peer, Y" uniqKey="Van De Peer Y">Y Van de Peer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jaillon, O" uniqKey="Jaillon O">O Jaillon</name></author><author><name sortKey="Aury, Jm" uniqKey="Aury J">JM Aury</name></author><author><name sortKey="Brunet, F" uniqKey="Brunet F">F Brunet</name></author><author><name sortKey="Petit, Jl" uniqKey="Petit J">JL Petit</name></author><author><name sortKey="Stange Thomann, N" uniqKey="Stange Thomann N">N Stange-Thomann</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Putnam, Nh" uniqKey="Putnam N">NH Putnam</name></author><author><name sortKey="Butts, T" uniqKey="Butts T">T Butts</name></author><author><name sortKey="Ferrier, Dek" uniqKey="Ferrier D">DEK Ferrier</name></author><author><name sortKey="Furlong, Rf" uniqKey="Furlong R">RF Furlong</name></author><author><name sortKey="Hellsten, U" uniqKey="Hellsten U">U Hellsten</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Holland, Lz" uniqKey="Holland L">LZ Holland</name></author><author><name sortKey="Albalat, R" uniqKey="Albalat R">R Albalat</name></author><author><name sortKey="Azumi, K" uniqKey="Azumi K">K Azumi</name></author><author><name sortKey="Benito Gutierrez, E" uniqKey="Benito Gutierrez E">È Benito-Gutiérrez</name></author><author><name sortKey="Blow, Mj" uniqKey="Blow M">MJ Blow</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Edger, Pp" uniqKey="Edger P">PP Edger</name></author><author><name sortKey="Pires, Jc" uniqKey="Pires J">JC Pires</name></author></analytic></biblStruct></listBibl></div1></back></TEI><pmc article-type="research-article"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">PLoS One</journal-id><journal-id journal-id-type="iso-abbrev">PLoS ONE</journal-id><journal-id journal-id-type="publisher-id">plos</journal-id><journal-id journal-id-type="pmc">plosone</journal-id><journal-title-group><journal-title>PLoS ONE</journal-title></journal-title-group><issn pub-type="epub">1932-6203</issn><publisher><publisher-name>Public Library of Science</publisher-name><publisher-loc>San Francisco, USA</publisher-loc></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">24066039</article-id><article-id pub-id-type="pmc">3774752</article-id><article-id pub-id-type="publisher-id">PONE-D-13-03124</article-id><article-id pub-id-type="doi">10.1371/journal.pone.0073217</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title>Assessment and Reconstruction of Novel HSP90 Genes: Duplications, Gains and Losses in Fungal and Animal Lineages</article-title><alt-title alt-title-type="running-head">Novel HSP90 Genes in Fungal and Animal Lineages</alt-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Pantzartzi</surname><given-names>Chrysoula N.</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref><xref ref-type="aff" rid="aff2"><sup>2</sup></xref><xref ref-type="corresp" rid="cor1"><sup>*</sup></xref></contrib><contrib contrib-type="author"><name><surname>Drosopoulou</surname><given-names>Elena</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author"><name><surname>Scouras</surname><given-names>Zacharias G.</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib></contrib-group><aff id="aff1"><label>1</label><addr-line>Department of Genetics, Development and Molecular Biology, School of Biology, Faculty of Sciences, Aristotle University of Thessaloniki, Thessaloniki, Greece</addr-line></aff><aff id="aff2"><label>2</label><addr-line>Department of Transcriptional Regulation, Institute of Molecular Genetics, Prague, Czech Republic</addr-line></aff><contrib-group><contrib contrib-type="editor"><name><surname>Brochier-Armanet</surname><given-names>Celine</given-names></name><role>Editor</role><xref ref-type="aff" rid="edit1"></xref></contrib></contrib-group><aff id="edit1"><addr-line>Université Claude Bernard – Lyon 1, France</addr-line></aff><author-notes><corresp id="cor1">* E-mail: <email>chrysap@img.cas.cz</email></corresp><fn fn-type="conflict"><p><bold>Competing Interests: </bold>The authors have declared that no competing interests exist.</p></fn><fn fn-type="con"><p>Conceived and designed the experiments: CNP ED ZGS. Analyzed the data: CNP. Wrote the paper: CNP ED ZGS.</p></fn></author-notes><pub-date pub-type="collection"><year>2013</year></pub-date><pub-date pub-type="epub"><day>16</day><month>9</month><year>2013</year></pub-date><volume>8</volume><issue>9</issue><elocation-id>e73217</elocation-id><history><date date-type="received"><day>18</day><month>1</month><year>2013</year></date><date date-type="accepted"><day>18</day><month>7</month><year>2013</year></date></history><permissions><copyright-year>2013</copyright-year><copyright-holder>Pantzartzi et al</copyright-holder><license><license-p>This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.</license-p></license></permissions><abstract><p>Hsp90s, members of the Heat Shock Protein class, protect the structure and function of proteins and play a significant task in cellular homeostasis and signal transduction. In order to determine the number of <italic>hsp90</italic> gene copies and encoded proteins in fungal and animal lineages and through that key duplication events that this family has undergone, we collected and evaluated Hsp90 protein sequences and corresponding Expressed Sequence Tags and analyzed available genomes from various taxa. We provide evidence for duplication events affecting either single species or wider taxonomic groups. With regard to Fungi, duplicated genes have been detected in several lineages. In invertebrates, we demonstrate key duplication events in certain clades of Arthropoda and Mollusca, and a possible gene loss event in a hymenopteran family. Finally, we infer that the duplication event responsible for the two (a and b) isoforms in vertebrates occurred probably shortly after the split of Hyperoartia and Gnathostomata.</p></abstract><funding-group><funding-statement>This publication was supported by intramural funds of the Aristotle University of Thessaloniki (Greece) to ZGS and ED and by the Academy of Sciences of the Czech Republic (RVO 68378050) and the project “BIOCEV – Biotechnology and Biomedicine Centre of the Academy of Sciences and Charles University” (CZ.1.05/1.1.00/02.0109), from the European Regional Development Fund to CNP. The funders had no role in study design, data collection and analysis, decision to publish or preparation of the manuscript.</funding-statement></funding-group><counts><page-count count="11"></page-count></counts></article-meta></front></pmc><affiliations><list><country><li>Grèce</li><li>République tchèque</li></country><region><li>Bohême centrale</li></region><settlement><li>Prague</li></settlement></list><tree><country name="Grèce"><noRegion><name sortKey="Pantzartzi, Chrysoula N" sort="Pantzartzi, Chrysoula N" uniqKey="Pantzartzi C" first="Chrysoula N." last="Pantzartzi">Chrysoula N. Pantzartzi</name></noRegion><name sortKey="Drosopoulou, Elena" sort="Drosopoulou, Elena" uniqKey="Drosopoulou E" first="Elena" last="Drosopoulou">Elena Drosopoulou</name><name sortKey="Scouras, Zacharias G" sort="Scouras, Zacharias G" uniqKey="Scouras Z" first="Zacharias G." last="Scouras">Zacharias G. Scouras</name></country><country name="République tchèque"><region name="Bohême centrale"><name sortKey="Pantzartzi, Chrysoula N" sort="Pantzartzi, Chrysoula N" uniqKey="Pantzartzi C" first="Chrysoula N." last="Pantzartzi">Chrysoula N. Pantzartzi</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Ticri/CIDE/explor/CyberinfraV1/Data/Pmc/Checkpoint
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000350 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Pmc/Checkpoint/biblio.hfd -nk 000350 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Ticri/CIDE
|area= CyberinfraV1
|flux= Pmc
|étape= Checkpoint
|type= RBID
|clé= PMC:3774752
|texte= Assessment and Reconstruction of Novel HSP90 Genes: Duplications, Gains and Losses in Fungal and Animal Lineages
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Pmc/Checkpoint/RBID.i -Sk "pubmed:24066039" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Pmc/Checkpoint/biblio.hfd \
| NlmPubMed2Wicri -a CyberinfraV1
| This area was generated with Dilib version V0.6.25. |  |