Somatotopic organization of human somatosensory cortices for pain: a single trial fMRI study.
Identifieur interne : 000676 ( PubMed/Curation ); précédent : 000675; suivant : 000677Somatotopic organization of human somatosensory cortices for pain: a single trial fMRI study.
Auteurs : U. Bingel [Allemagne] ; J. Lorenz ; V. Glauche ; R. Knab ; J. Gl Scher ; C. Weiller ; C. BüchelSource :
- NeuroImage [ 1053-8119 ] ; 2004.
Descripteurs français
- KwdFr :
- Adulte, Cartographie cérébrale, Cortex somatosensoriel (physiologie), Dominance cérébrale (physiologie), Femelle, Humains, Imagerie par résonance magnétique, Imagerie tridimensionnelle, Lasers, Latéralité fonctionnelle (physiologie), Main (innervation), Mâle, Mécanorécepteurs (physiologie), Nocicepteurs (physiologie), Orientation (physiologie), Peau (innervation), Pied (innervation), Seuil nociceptif (physiologie), Température cutanée (physiologie), Toucher (physiologie), Traitement d'image par ordinateur, Valeurs de référence, Voies afférentes (physiologie).
- MESH :
- physiologie : Cortex somatosensoriel, Dominance cérébrale, Latéralité fonctionnelle, Mécanorécepteurs, Nocicepteurs, Orientation, Seuil nociceptif, Température cutanée, Toucher, Voies afférentes.
- innervation : Adulte, Cartographie cérébrale, Femelle, Humains, Imagerie par résonance magnétique, Imagerie tridimensionnelle, Lasers, Main, Mâle, Peau, Pied, Traitement d'image par ordinateur, Valeurs de référence.
English descriptors
- KwdEn :
- Adult, Afferent Pathways (physiology), Brain Mapping, Dominance, Cerebral (physiology), Female, Foot (innervation), Functional Laterality (physiology), Hand (innervation), Humans, Image Processing, Computer-Assisted, Imaging, Three-Dimensional, Lasers, Magnetic Resonance Imaging, Male, Mechanoreceptors (physiology), Nociceptors (physiology), Orientation (physiology), Pain Threshold (physiology), Reference Values, Skin (innervation), Skin Temperature (physiology), Somatosensory Cortex (physiology), Touch (physiology).
- MESH :
- innervation : Foot, Hand, Skin.
- physiology : Afferent Pathways, Dominance, Cerebral, Functional Laterality, Mechanoreceptors, Nociceptors, Orientation, Pain Threshold, Skin Temperature, Somatosensory Cortex, Touch.
- Adult, Brain Mapping, Female, Humans, Image Processing, Computer-Assisted, Imaging, Three-Dimensional, Lasers, Magnetic Resonance Imaging, Male, Reference Values.
Abstract
The ability to locate pain plays a pivotal role in immediate defense and withdrawal behavior. However, how the brain localizes nociceptive information without additional information from somatotopically organized mechano-receptive pathways is not well understood. To investigate the somatotopic organization of the nociceptive system, we applied Thulium-YAG-laser evoked pain stimuli, which have no concomitant tactile component, to the dorsum of the left hand and foot in randomized order. We used single-trial functional magnetic resonance imaging (fMRI) to assess differential hemodynamic responses to hand and foot stimulation for the group and in a single subject approach. The primary somatosensory cortex (SI) shows a clear somatotopic organization ipsi- and contralaterally to painful stimulation. Furthermore, a differential representation of hand and foot stimulation appeared within the contralateral opercular--insular region of the secondary somatosensory cortex (SII). This result provides evidence that both SI and SII encode spatial information of nociceptive stimuli without additional information from the tactile system and highlights the concept of a redundant representation of basic discriminative stimulus features in human somatosensory cortices, which seems adequate in view of the evolutionary importance of pain perception.
DOI: 10.1016/j.neuroimage.2004.05.021
PubMed: 15325369
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Bingel</name><affiliation wicri:level="1"><nlm:affiliation>Cognitive Neuroscience Laboratory, Department of Neurology, Hamburg University Medical School, Germany. bingel@uke.uni-hamburg.de</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Cognitive Neuroscience Laboratory, Department of Neurology, Hamburg University Medical School</wicri:regionArea></affiliation></author><author><name sortKey="Lorenz, J" sort="Lorenz, J" uniqKey="Lorenz J" first="J" last="Lorenz">J. Lorenz</name></author><author><name sortKey="Glauche, V" sort="Glauche, V" uniqKey="Glauche V" first="V" last="Glauche">V. Glauche</name></author><author><name sortKey="Knab, R" sort="Knab, R" uniqKey="Knab R" first="R" last="Knab">R. Knab</name></author><author><name sortKey="Gl Scher, J" sort="Gl Scher, J" uniqKey="Gl Scher J" first="J" last="Gl Scher">J. Gl Scher</name></author><author><name sortKey="Weiller, C" sort="Weiller, C" uniqKey="Weiller C" first="C" last="Weiller">C. 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However, how the brain localizes nociceptive information without additional information from somatotopically organized mechano-receptive pathways is not well understood. To investigate the somatotopic organization of the nociceptive system, we applied Thulium-YAG-laser evoked pain stimuli, which have no concomitant tactile component, to the dorsum of the left hand and foot in randomized order. We used single-trial functional magnetic resonance imaging (fMRI) to assess differential hemodynamic responses to hand and foot stimulation for the group and in a single subject approach. The primary somatosensory cortex (SI) shows a clear somatotopic organization ipsi- and contralaterally to painful stimulation. Furthermore, a differential representation of hand and foot stimulation appeared within the contralateral opercular--insular region of the secondary somatosensory cortex (SII). This result provides evidence that both SI and SII encode spatial information of nociceptive stimuli without additional information from the tactile system and highlights the concept of a redundant representation of basic discriminative stimulus features in human somatosensory cortices, which seems adequate in view of the evolutionary importance of pain perception.</div></front></TEI><pubmed><MedlineCitation Owner="NLM" Status="MEDLINE"><PMID Version="1">15325369</PMID><DateCreated><Year>2004</Year><Month>08</Month><Day>24</Day></DateCreated><DateCompleted><Year>2004</Year><Month>11</Month><Day>30</Day></DateCompleted><DateRevised><Year>2015</Year><Month>11</Month><Day>19</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">1053-8119</ISSN><JournalIssue CitedMedium="Print"><Volume>23</Volume><Issue>1</Issue><PubDate><Year>2004</Year><Month>Sep</Month></PubDate></JournalIssue><Title>NeuroImage</Title><ISOAbbreviation>Neuroimage</ISOAbbreviation></Journal><ArticleTitle>Somatotopic organization of human somatosensory cortices for pain: a single trial fMRI study.</ArticleTitle><Pagination><MedlinePgn>224-32</MedlinePgn></Pagination><Abstract><AbstractText>The ability to locate pain plays a pivotal role in immediate defense and withdrawal behavior. However, how the brain localizes nociceptive information without additional information from somatotopically organized mechano-receptive pathways is not well understood. To investigate the somatotopic organization of the nociceptive system, we applied Thulium-YAG-laser evoked pain stimuli, which have no concomitant tactile component, to the dorsum of the left hand and foot in randomized order. We used single-trial functional magnetic resonance imaging (fMRI) to assess differential hemodynamic responses to hand and foot stimulation for the group and in a single subject approach. The primary somatosensory cortex (SI) shows a clear somatotopic organization ipsi- and contralaterally to painful stimulation. Furthermore, a differential representation of hand and foot stimulation appeared within the contralateral opercular--insular region of the secondary somatosensory cortex (SII). This result provides evidence that both SI and SII encode spatial information of nociceptive stimuli without additional information from the tactile system and highlights the concept of a redundant representation of basic discriminative stimulus features in human somatosensory cortices, which seems adequate in view of the evolutionary importance of pain perception.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Bingel</LastName><ForeName>U</ForeName><Initials>U</Initials><AffiliationInfo><Affiliation>Cognitive Neuroscience Laboratory, Department of Neurology, Hamburg University Medical School, Germany. bingel@uke.uni-hamburg.de</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lorenz</LastName><ForeName>J</ForeName><Initials>J</Initials></Author><Author ValidYN="Y"><LastName>Glauche</LastName><ForeName>V</ForeName><Initials>V</Initials></Author><Author ValidYN="Y"><LastName>Knab</LastName><ForeName>R</ForeName><Initials>R</Initials></Author><Author ValidYN="Y"><LastName>Gläscher</LastName><ForeName>J</ForeName><Initials>J</Initials></Author><Author ValidYN="Y"><LastName>Weiller</LastName><ForeName>C</ForeName><Initials>C</Initials></Author><Author ValidYN="Y"><LastName>Büchel</LastName><ForeName>C</ForeName><Initials>C</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Neuroimage</MedlineTA><NlmUniqueID>9215515</NlmUniqueID><ISSNLinking>1053-8119</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName MajorTopicYN="N" UI="D000328">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D000344">Afferent Pathways</DescriptorName><QualifierName MajorTopicYN="N" UI="Q000502">physiology</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D001931">Brain Mapping</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D004292">Dominance, Cerebral</DescriptorName><QualifierName MajorTopicYN="N" UI="Q000502">physiology</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D005260">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D005528">Foot</DescriptorName><QualifierName MajorTopicYN="Y" UI="Q000294">innervation</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D007839">Functional Laterality</DescriptorName><QualifierName MajorTopicYN="N" UI="Q000502">physiology</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D006225">Hand</DescriptorName><QualifierName MajorTopicYN="Y" 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UI="Q000502">physiology</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D009949">Orientation</DescriptorName><QualifierName MajorTopicYN="N" UI="Q000502">physiology</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D017288">Pain Threshold</DescriptorName><QualifierName MajorTopicYN="N" UI="Q000502">physiology</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D012016">Reference Values</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D012867">Skin</DescriptorName><QualifierName MajorTopicYN="Y" UI="Q000294">innervation</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D012881">Skin Temperature</DescriptorName><QualifierName MajorTopicYN="N" UI="Q000502">physiology</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D013003">Somatosensory Cortex</DescriptorName><QualifierName MajorTopicYN="Y" UI="Q000502">physiology</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D014110">Touch</DescriptorName><QualifierName MajorTopicYN="N" UI="Q000502">physiology</QualifierName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>2004</Year><Month>8</Month><Day>25</Day><Hour>5</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2004</Year><Month>12</Month><Day>16</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="received"><Year>2004</Year><Month>Jan</Month><Day>29</Day></PubMedPubDate><PubMedPubDate PubStatus="revised"><Year>2004</Year><Month>May</Month><Day>5</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2004</Year><Month>May</Month><Day>13</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2004</Year><Month>8</Month><Day>25</Day><Hour>5</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">15325369</ArticleId><ArticleId IdType="doi">10.1016/j.neuroimage.2004.05.021</ArticleId><ArticleId IdType="pii">S1053811904003003</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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