Efficacy and safety profile of a novel technique, ThuLEP (Thulium laser enucleation of the prostate) for the treatment of benign prostate hypertrophy. Our experience on 148 patients.
Identifieur interne : 000325 ( PubMed/Curation ); précédent : 000324; suivant : 000326Efficacy and safety profile of a novel technique, ThuLEP (Thulium laser enucleation of the prostate) for the treatment of benign prostate hypertrophy. Our experience on 148 patients.
Auteurs : Fabrizio Iacono [Italie] ; Domenico Prezioso ; Giovanni Di Lauro ; Giuseppe Romeo ; Antonio Ruffo ; Ester Illiano ; Bruno AmatoSource :
- BMC surgery [ 1471-2482 ] ; 2012.
Descripteurs français
- KwdFr :
- Adulte d'âge moyen, Complications postopératoires (épidémiologie), Humains, Hyperplasie de la prostate (), Lasers à solide (effets indésirables), Lasers à solide (usage thérapeutique), Mâle, Prostatectomie (), Prostatectomie (effets indésirables), Résultat thérapeutique, Sujet âgé, Sujet âgé de 80 ans ou plus, Thulium, Études de suivi.
- MESH :
- effets indésirables : Lasers à solide, Prostatectomie.
- usage thérapeutique : Lasers à solide.
- épidémiologie : Complications postopératoires.
- Adulte d'âge moyen, Humains, Hyperplasie de la prostate, Mâle, Prostatectomie, Résultat thérapeutique, Sujet âgé, Sujet âgé de 80 ans ou plus, Thulium, Études de suivi.
English descriptors
- KwdEn :
- Aged, Aged, 80 and over, Follow-Up Studies, Humans, Lasers, Solid-State (adverse effects), Lasers, Solid-State (therapeutic use), Male, Middle Aged, Postoperative Complications (epidemiology), Prostatectomy (adverse effects), Prostatectomy (methods), Prostatic Hyperplasia (surgery), Thulium, Treatment Outcome.
- MESH :
- chemical : Thulium.
- adverse effects : Lasers, Solid-State, Prostatectomy.
- epidemiology : Postoperative Complications.
- methods : Prostatectomy.
- surgery : Prostatic Hyperplasia.
- therapeutic use : Lasers, Solid-State.
- Aged, Aged, 80 and over, Follow-Up Studies, Humans, Male, Middle Aged, Treatment Outcome.
Abstract
Over the past years laser technology has played a predominant role in prostate surgery, for the treatment of benign prostate hypertrophy (BPH). Various laser devices have been introduced in clinical practice, showing good results in terms of complications and urodynamic outcomes efficacy compared with TURP and Open Prostatectomy.In this study we describe the efficacy and the safety profile of a novel laser technique, ThuLEP (Thulium Laser Enucleation of Prostate) that permits a complete anatomical endoscopic enucleation of prostatic adenoma independently to prostate size.
DOI: 10.1186/1471-2482-12-S1-S21
PubMed: 23173611
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Our experience on 148 patients.</title><author><name sortKey="Iacono, Fabrizio" sort="Iacono, Fabrizio" uniqKey="Iacono F" first="Fabrizio" last="Iacono">Fabrizio Iacono</name><affiliation wicri:level="1"><nlm:affiliation>Department of Urology, School of Medicine, University Federico II of Naples, Via pasini 5, 80131 Naples, Italy. fiacon@tin.it</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Urology, School of Medicine, University Federico II of Naples, Via pasini 5, 80131 Naples</wicri:regionArea></affiliation></author><author><name sortKey="Prezioso, Domenico" sort="Prezioso, Domenico" uniqKey="Prezioso D" first="Domenico" last="Prezioso">Domenico Prezioso</name></author><author><name sortKey="Di Lauro, Giovanni" sort="Di Lauro, Giovanni" uniqKey="Di Lauro G" first="Giovanni" last="Di Lauro">Giovanni Di Lauro</name></author><author><name sortKey="Romeo, Giuseppe" sort="Romeo, Giuseppe" uniqKey="Romeo G" first="Giuseppe" last="Romeo">Giuseppe Romeo</name></author><author><name sortKey="Ruffo, Antonio" sort="Ruffo, Antonio" uniqKey="Ruffo A" first="Antonio" last="Ruffo">Antonio Ruffo</name></author><author><name sortKey="Illiano, Ester" sort="Illiano, Ester" uniqKey="Illiano E" first="Ester" last="Illiano">Ester Illiano</name></author><author><name sortKey="Amato, Bruno" sort="Amato, Bruno" uniqKey="Amato B" first="Bruno" last="Amato">Bruno Amato</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2012">2012</date><idno type="doi">10.1186/1471-2482-12-S1-S21</idno><idno type="RBID">pubmed:23173611</idno><idno type="pmid">23173611</idno><idno type="wicri:Area/PubMed/Corpus">000325</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000325</idno><idno type="wicri:Area/PubMed/Curation">000325</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000325</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Efficacy and safety profile of a novel technique, ThuLEP (Thulium laser enucleation of the prostate) for the treatment of benign prostate hypertrophy. Our experience on 148 patients.</title><author><name sortKey="Iacono, Fabrizio" sort="Iacono, Fabrizio" uniqKey="Iacono F" first="Fabrizio" last="Iacono">Fabrizio Iacono</name><affiliation wicri:level="1"><nlm:affiliation>Department of Urology, School of Medicine, University Federico II of Naples, Via pasini 5, 80131 Naples, Italy. fiacon@tin.it</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Urology, School of Medicine, University Federico II of Naples, Via pasini 5, 80131 Naples</wicri:regionArea></affiliation></author><author><name sortKey="Prezioso, Domenico" sort="Prezioso, Domenico" uniqKey="Prezioso D" first="Domenico" last="Prezioso">Domenico Prezioso</name></author><author><name sortKey="Di Lauro, Giovanni" sort="Di Lauro, Giovanni" uniqKey="Di Lauro G" first="Giovanni" last="Di Lauro">Giovanni Di Lauro</name></author><author><name sortKey="Romeo, Giuseppe" sort="Romeo, Giuseppe" uniqKey="Romeo G" first="Giuseppe" last="Romeo">Giuseppe Romeo</name></author><author><name sortKey="Ruffo, Antonio" sort="Ruffo, Antonio" uniqKey="Ruffo A" first="Antonio" last="Ruffo">Antonio Ruffo</name></author><author><name sortKey="Illiano, Ester" sort="Illiano, Ester" uniqKey="Illiano E" first="Ester" last="Illiano">Ester Illiano</name></author><author><name sortKey="Amato, Bruno" sort="Amato, Bruno" uniqKey="Amato B" first="Bruno" last="Amato">Bruno Amato</name></author></analytic><series><title level="j">BMC surgery</title><idno type="eISSN">1471-2482</idno><imprint><date when="2012" type="published">2012</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged</term><term>Aged, 80 and over</term><term>Follow-Up Studies</term><term>Humans</term><term>Lasers, Solid-State (adverse effects)</term><term>Lasers, Solid-State (therapeutic use)</term><term>Male</term><term>Middle Aged</term><term>Postoperative Complications (epidemiology)</term><term>Prostatectomy (adverse effects)</term><term>Prostatectomy (methods)</term><term>Prostatic Hyperplasia (surgery)</term><term>Thulium</term><term>Treatment Outcome</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adulte d'âge moyen</term><term>Complications postopératoires (épidémiologie)</term><term>Humains</term><term>Hyperplasie de la prostate ()</term><term>Lasers à solide (effets indésirables)</term><term>Lasers à solide (usage thérapeutique)</term><term>Mâle</term><term>Prostatectomie ()</term><term>Prostatectomie (effets indésirables)</term><term>Résultat thérapeutique</term><term>Sujet âgé</term><term>Sujet âgé de 80 ans ou plus</term><term>Thulium</term><term>Études de suivi</term></keywords><keywords scheme="MESH" type="chemical" xml:lang="en"><term>Thulium</term></keywords><keywords scheme="MESH" qualifier="adverse effects" xml:lang="en"><term>Lasers, Solid-State</term><term>Prostatectomy</term></keywords><keywords scheme="MESH" qualifier="effets indésirables" xml:lang="fr"><term>Lasers à solide</term><term>Prostatectomie</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Postoperative Complications</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Prostatectomy</term></keywords><keywords scheme="MESH" qualifier="surgery" xml:lang="en"><term>Prostatic Hyperplasia</term></keywords><keywords scheme="MESH" qualifier="therapeutic use" xml:lang="en"><term>Lasers, Solid-State</term></keywords><keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Lasers à solide</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Complications postopératoires</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Aged</term><term>Aged, 80 and over</term><term>Follow-Up Studies</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Treatment Outcome</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adulte d'âge moyen</term><term>Humains</term><term>Hyperplasie de la prostate</term><term>Mâle</term><term>Prostatectomie</term><term>Résultat thérapeutique</term><term>Sujet âgé</term><term>Sujet âgé de 80 ans ou plus</term><term>Thulium</term><term>Études de suivi</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Over the past years laser technology has played a predominant role in prostate surgery, for the treatment of benign prostate hypertrophy (BPH). Various laser devices have been introduced in clinical practice, showing good results in terms of complications and urodynamic outcomes efficacy compared with TURP and Open Prostatectomy.In this study we describe the efficacy and the safety profile of a novel laser technique, ThuLEP (Thulium Laser Enucleation of Prostate) that permits a complete anatomical endoscopic enucleation of prostatic adenoma independently to prostate size.</div></front></TEI><pubmed><MedlineCitation Owner="NLM" Status="MEDLINE"><PMID Version="1">23173611</PMID><DateCreated><Year>2012</Year><Month>11</Month><Day>23</Day></DateCreated><DateCompleted><Year>2013</Year><Month>05</Month><Day>21</Day></DateCompleted><DateRevised><Year>2015</Year><Month>02</Month><Day>22</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1471-2482</ISSN><JournalIssue CitedMedium="Internet"><Volume>12 Suppl 1</Volume><PubDate><Year>2012</Year></PubDate></JournalIssue><Title>BMC surgery</Title><ISOAbbreviation>BMC Surg</ISOAbbreviation></Journal><ArticleTitle>Efficacy and safety profile of a novel technique, ThuLEP (Thulium laser enucleation of the prostate) for the treatment of benign prostate hypertrophy. Our experience on 148 patients.</ArticleTitle><Pagination><MedlinePgn>S21</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1186/1471-2482-12-S1-S21</ELocationID><Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Over the past years laser technology has played a predominant role in prostate surgery, for the treatment of benign prostate hypertrophy (BPH). Various laser devices have been introduced in clinical practice, showing good results in terms of complications and urodynamic outcomes efficacy compared with TURP and Open Prostatectomy.In this study we describe the efficacy and the safety profile of a novel laser technique, ThuLEP (Thulium Laser Enucleation of Prostate) that permits a complete anatomical endoscopic enucleation of prostatic adenoma independently to prostate size.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">148 patients with a mean age of 68.2 years were enrolled between September 2009 and March 2012 (36 months), and treated for BPH with ThuLEP. Every patient was evaluated at base line according to: Digital Rectal Examination (DRE), prostate volume, Post-Voided volume (PVR), International Prostate Symptoms Score (I-PSS), International Index of Erectile Function-5 (IIEF-5), Quality of Life (QoL), PSA values, urine analysis and urine culture, uroflowmetry. The same evaluation was conducted after a 12 month follow-up. ThuLEP was performed by 2 expert surgeons.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">Our data showed a better post-operative outcome in terms of catheter removal, blood loss, TURP syndrome, clot retention and residual tissue compared to large series of TURP and OP. Only 1.3% of patients had bladder wall injury during morcellation. I-PSS, Qmax, Prostate Volume, QoL and PVR showed a highly significant improvement at 12 month follow-up in comparison to preoperative assessment.</AbstractText><AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">ThuLEP represent an innovative option in patients with BPH. It is a size independent surgical endoscopic technique and it can be considered the real alternative, at this time, to TURP and even more to Open Prostatectomy for large prostate, with a complete removal of adenoma and with a low complication rate.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Iacono</LastName><ForeName>Fabrizio</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>Department of Urology, School of Medicine, University Federico II of Naples, Via pasini 5, 80131 Naples, Italy. fiacon@tin.it</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Prezioso</LastName><ForeName>Domenico</ForeName><Initials>D</Initials></Author><Author ValidYN="Y"><LastName>Di Lauro</LastName><ForeName>Giovanni</ForeName><Initials>G</Initials></Author><Author ValidYN="Y"><LastName>Romeo</LastName><ForeName>Giuseppe</ForeName><Initials>G</Initials></Author><Author ValidYN="Y"><LastName>Ruffo</LastName><ForeName>Antonio</ForeName><Initials>A</Initials></Author><Author ValidYN="Y"><LastName>Illiano</LastName><ForeName>Ester</ForeName><Initials>E</Initials></Author><Author ValidYN="Y"><LastName>Amato</LastName><ForeName>Bruno</ForeName><Initials>B</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D023362">Evaluation Studies</PublicationType><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2012</Year><Month>11</Month><Day>15</Day></ArticleDate></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>BMC Surg</MedlineTA><NlmUniqueID>100968567</NlmUniqueID><ISSNLinking>1471-2482</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>8RKC5ATI4P</RegistryNumber><NameOfSubstance UI="D013932">Thulium</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><CommentsCorrectionsList><CommentsCorrections RefType="Cites"><RefSource>Urology. 2002 Oct;60(4):623-7</RefSource><PMID Version="1">12385922</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Eur Urol. 2010 Sep;58(3):384-97</RefSource><PMID Version="1">20825758</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Scand J Urol Nephrol. 2003;37(6):494-7</RefSource><PMID Version="1">14675923</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Urology. 1994 Apr;43(4):467-71</RefSource><PMID Version="1">7512297</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Eur Urol. 1998 Dec;34(6):480-5</RefSource><PMID Version="1">9831789</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Urol. 2004 Nov;172(5 Pt 1):1926-9</RefSource><PMID 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Sep;39(5):359-68</RefSource><PMID Version="1">18798125</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Urology. 2010 Jan;75(1):194-9</RefSource><PMID Version="1">19819535</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>World J Urol. 2010 Feb;28(1):45-51</RefSource><PMID Version="1">20063164</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>BJU Int. 2010 Aug;106(3):368-72</RefSource><PMID Version="1">19912204</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Urology. 2003 Dec;62(6):1029-34</RefSource><PMID Version="1">14665349</PMID></CommentsCorrections></CommentsCorrectionsList><MeshHeadingList><MeshHeading><DescriptorName MajorTopicYN="N" UI="D000368">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D000369">Aged, 80 and over</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D005500">Follow-Up Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D006801">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D053844">Lasers, Solid-State</DescriptorName><QualifierName MajorTopicYN="N" UI="Q000009">adverse effects</QualifierName><QualifierName MajorTopicYN="Y" UI="Q000627">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D008297">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D008875">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D011183">Postoperative Complications</DescriptorName><QualifierName MajorTopicYN="N" UI="Q000453">epidemiology</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D011468">Prostatectomy</DescriptorName><QualifierName MajorTopicYN="N" UI="Q000009">adverse effects</QualifierName><QualifierName MajorTopicYN="Y" UI="Q000379">methods</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D011470">Prostatic Hyperplasia</DescriptorName><QualifierName MajorTopicYN="Y" UI="Q000601">surgery</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D013932">Thulium</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D016896">Treatment Outcome</DescriptorName></MeshHeading></MeshHeadingList><OtherID Source="NLM">PMC3499280</OtherID></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="aheadofprint"><Year>2012</Year><Month>11</Month><Day>15</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2012</Year><Month>11</Month><Day>24</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2012</Year><Month>11</Month><Day>28</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2013</Year><Month>5</Month><Day>23</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pii">1471-2482-12-S1-S21</ArticleId><ArticleId IdType="doi">10.1186/1471-2482-12-S1-S21</ArticleId><ArticleId IdType="pubmed">23173611</ArticleId><ArticleId IdType="pmc">PMC3499280</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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