ThuliumV1, PubMed, Corpus, bibRecord, 000802

THC:YAG laser sclerostomy with mitomycin subconjunctival injection in rabbits.

Identifieur interne : 000802 ( PubMed/Corpus ); précédent : 000801; suivant : 000803

THC:YAG laser sclerostomy with mitomycin subconjunctival injection in rabbits.

Auteurs : T H Wang ; P T Hung ; T C Ho

Source :

Journal of ocular pharmacology [ 8756-3320 ] ; 1992.

RBID : pubmed:1484263

English descriptors

KwdEn :
- Animals, Conjunctiva (drug effects), Conjunctiva (pathology), Fibrosis (prevention & control), Injections, Intraocular Pressure (drug effects), Laser Therapy, Mitomycins (administration & dosage), Mitomycins (therapeutic use), Rabbits, Sclerostomy, Wound Healing (drug effects).
MESH :
- chemical , administration & dosage : Mitomycins.
- drug effects : Conjunctiva, Intraocular Pressure, Wound Healing.
- pathology : Conjunctiva.
- prevention & control : Fibrosis.
- chemical , therapeutic use : Mitomycins.
- Animals, Injections, Laser Therapy, Rabbits, Sclerostomy.

Abstract

We performed sclerostomy using THC:YAG laser (thulium, holmium, chromium doped YAG crystal) and subconjunctival injection of mitomycin soon after the filtering process in rabbits to observe the lowering effect of intraocular pressure(IOP) and filtering bleb formation. A 1-mm conjunctiva wound was made 12 mm away from the sclerostomy site to allow the entry of the optic probe for delivering energy. Forty-eight rabbits were divided into 3 groups. After sclerostomy, Group I received 0.2 ml normal saline subconjunctival injection and Group II and III received 0.2 ml mitomycin injection of 0.1 and 0.2 mg/ml respectively. One eye of each rabbit was randomly selected for the experiment while the fellow eye served as control. The bleb lasted 1.4 +/- 0.5 days (or 1 to 2 days) in Group I, 8.5 +/- 4.5 days (or 4 to 17 days) in Group II and 15.4 +/- 10.9 days (or 4 to 37 days) in Group III. The IOP lowering effect was significantly enhanced in Group III. The postoperative complication was minimal corneal punctate erosion in the mitomycin group, but all of them, however, resolved within one week. The results demonstrated that mitomycin is effective in prolonging the filtering effect produced by the THC:YAG laser.

PubMed: 1484263

Links to Exploration step

pubmed:1484263

Le document en format XML

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<author><name sortKey="Wang, T H" sort="Wang, T H" uniqKey="Wang T" first="T H" last="Wang">T H Wang</name>
<affiliation><nlm:affiliation>Department of Ophthalmology, National Taiwan University Hospital, Taipei.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Hung, P T" sort="Hung, P T" uniqKey="Hung P" first="P T" last="Hung">P T Hung</name>
</author>
<author><name sortKey="Ho, T C" sort="Ho, T C" uniqKey="Ho T" first="T C" last="Ho">T C Ho</name>
</author>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">THC:YAG laser sclerostomy with mitomycin subconjunctival injection in rabbits.</title>
<author><name sortKey="Wang, T H" sort="Wang, T H" uniqKey="Wang T" first="T H" last="Wang">T H Wang</name>
<affiliation><nlm:affiliation>Department of Ophthalmology, National Taiwan University Hospital, Taipei.</nlm:affiliation>
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<author><name sortKey="Hung, P T" sort="Hung, P T" uniqKey="Hung P" first="P T" last="Hung">P T Hung</name>
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<author><name sortKey="Ho, T C" sort="Ho, T C" uniqKey="Ho T" first="T C" last="Ho">T C Ho</name>
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<series><title level="j">Journal of ocular pharmacology</title>
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<imprint><date when="1992" type="published">1992</date>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term>
<term>Conjunctiva (drug effects)</term>
<term>Conjunctiva (pathology)</term>
<term>Fibrosis (prevention & control)</term>
<term>Injections</term>
<term>Intraocular Pressure (drug effects)</term>
<term>Laser Therapy</term>
<term>Mitomycins (administration & dosage)</term>
<term>Mitomycins (therapeutic use)</term>
<term>Rabbits</term>
<term>Sclerostomy</term>
<term>Wound Healing (drug effects)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="administration & dosage" xml:lang="en"><term>Mitomycins</term>
</keywords>
<keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Conjunctiva</term>
<term>Intraocular Pressure</term>
<term>Wound Healing</term>
</keywords>
<keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Conjunctiva</term>
</keywords>
<keywords scheme="MESH" qualifier="prevention & control" xml:lang="en"><term>Fibrosis</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Mitomycins</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Animals</term>
<term>Injections</term>
<term>Laser Therapy</term>
<term>Rabbits</term>
<term>Sclerostomy</term>
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<front><div type="abstract" xml:lang="en">We performed sclerostomy using THC:YAG laser (thulium, holmium, chromium doped YAG crystal) and subconjunctival injection of mitomycin soon after the filtering process in rabbits to observe the lowering effect of intraocular pressure(IOP) and filtering bleb formation. A 1-mm conjunctiva wound was made 12 mm away from the sclerostomy site to allow the entry of the optic probe for delivering energy. Forty-eight rabbits were divided into 3 groups. After sclerostomy, Group I received 0.2 ml normal saline subconjunctival injection and Group II and III received 0.2 ml mitomycin injection of 0.1 and 0.2 mg/ml respectively. One eye of each rabbit was randomly selected for the experiment while the fellow eye served as control. The bleb lasted 1.4 +/- 0.5 days (or 1 to 2 days) in Group I, 8.5 +/- 4.5 days (or 4 to 17 days) in Group II and 15.4 +/- 10.9 days (or 4 to 37 days) in Group III. The IOP lowering effect was significantly enhanced in Group III. The postoperative complication was minimal corneal punctate erosion in the mitomycin group, but all of them, however, resolved within one week. The results demonstrated that mitomycin is effective in prolonging the filtering effect produced by the THC:YAG laser.</div>
</front>
</TEI>
<pubmed><MedlineCitation Owner="NLM" Status="MEDLINE"><PMID Version="1">1484263</PMID>
<DateCreated><Year>1993</Year>
<Month>02</Month>
<Day>17</Day>
</DateCreated>
<DateCompleted><Year>1993</Year>
<Month>02</Month>
<Day>17</Day>
</DateCompleted>
<DateRevised><Year>2007</Year>
<Month>11</Month>
<Day>15</Day>
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<Article PubModel="Print"><Journal><ISSN IssnType="Print">8756-3320</ISSN>
<JournalIssue CitedMedium="Print"><Volume>8</Volume>
<Issue>4</Issue>
<PubDate><Year>1992</Year>
<Season>Winter</Season>
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<Title>Journal of ocular pharmacology</Title>
<ISOAbbreviation>J Ocul Pharmacol</ISOAbbreviation>
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<ArticleTitle>THC:YAG laser sclerostomy with mitomycin subconjunctival injection in rabbits.</ArticleTitle>
<Pagination><MedlinePgn>325-32</MedlinePgn>
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<Abstract><AbstractText>We performed sclerostomy using THC:YAG laser (thulium, holmium, chromium doped YAG crystal) and subconjunctival injection of mitomycin soon after the filtering process in rabbits to observe the lowering effect of intraocular pressure(IOP) and filtering bleb formation. A 1-mm conjunctiva wound was made 12 mm away from the sclerostomy site to allow the entry of the optic probe for delivering energy. Forty-eight rabbits were divided into 3 groups. After sclerostomy, Group I received 0.2 ml normal saline subconjunctival injection and Group II and III received 0.2 ml mitomycin injection of 0.1 and 0.2 mg/ml respectively. One eye of each rabbit was randomly selected for the experiment while the fellow eye served as control. The bleb lasted 1.4 +/- 0.5 days (or 1 to 2 days) in Group I, 8.5 +/- 4.5 days (or 4 to 17 days) in Group II and 15.4 +/- 10.9 days (or 4 to 37 days) in Group III. The IOP lowering effect was significantly enhanced in Group III. The postoperative complication was minimal corneal punctate erosion in the mitomycin group, but all of them, however, resolved within one week. The results demonstrated that mitomycin is effective in prolonging the filtering effect produced by the THC:YAG laser.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Wang</LastName>
<ForeName>T H</ForeName>
<Initials>TH</Initials>
<AffiliationInfo><Affiliation>Department of Ophthalmology, National Taiwan University Hospital, Taipei.</Affiliation>
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<Author ValidYN="Y"><LastName>Hung</LastName>
<ForeName>P T</ForeName>
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<Author ValidYN="Y"><LastName>Ho</LastName>
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<MedlineJournalInfo><Country>UNITED STATES</Country>
<MedlineTA>J Ocul Pharmacol</MedlineTA>
<NlmUniqueID>8511297</NlmUniqueID>
<ISSNLinking>8756-3320</ISSNLinking>
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<MeshHeadingList><MeshHeading><DescriptorName MajorTopicYN="N" UI="D000818">Animals</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D003228">Conjunctiva</DescriptorName>
<QualifierName MajorTopicYN="N" UI="Q000187">drug effects</QualifierName>
<QualifierName MajorTopicYN="N" UI="Q000473">pathology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D005355">Fibrosis</DescriptorName>
<QualifierName MajorTopicYN="N" UI="Q000517">prevention & control</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D007267">Injections</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D007429">Intraocular Pressure</DescriptorName>
<QualifierName MajorTopicYN="N" UI="Q000187">drug effects</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="Y" UI="D053685">Laser Therapy</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D008937">Mitomycins</DescriptorName>
<QualifierName MajorTopicYN="N" UI="Q000008">administration & dosage</QualifierName>
<QualifierName MajorTopicYN="Y" UI="Q000627">therapeutic use</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D011817">Rabbits</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="Y" UI="D012599">Sclerostomy</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D014945">Wound Healing</DescriptorName>
<QualifierName MajorTopicYN="N" UI="Q000187">drug effects</QualifierName>
</MeshHeading>
</MeshHeadingList>
</MedlineCitation>
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THC:YAG laser sclerostomy with mitomycin subconjunctival injection in rabbits.

THC:YAG laser sclerostomy with mitomycin subconjunctival injection in rabbits.

Source :

English descriptors

Abstract

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki