Systematic evaluation of a recently introduced 2-microm continuous-wave thulium laser for vaporesection of the prostate.
Identifieur interne : 000588 ( PubMed/Corpus ); précédent : 000587; suivant : 000589Systematic evaluation of a recently introduced 2-microm continuous-wave thulium laser for vaporesection of the prostate.
Auteurs : Gunnar Wendt-Nordahl ; Stephanie Huckele ; Patrick Honeck ; Peter Alken ; Thomas Knoll ; Maurice Stephan Michel ; Axel H CkerSource :
- Journal of endourology / Endourological Society [ 0892-7790 ] ; 2008.
English descriptors
- KwdEn :
- MESH :
- chemical : Thulium.
- blood supply : Kidney.
- pathology : Kidney.
- surgery : Kidney.
- Animals, Blood Loss, Surgical, Laser Therapy, Lasers, Solid-State, Models, Animal, Swine, Transurethral Resection of Prostate.
Abstract
A novel 2-microm continuous wave (CW) thulium laser device for interventional treatment of benign prostatic hyperplasia was recently introduced into clinical practice and is postulated to have several advantages over more established laser devices. A systematic ex-vivo evaluation of the thulium laser was undertaken to compare the results to transurethral resection of the prostate (TURP) and the potassium-titanyl-phosphate (KTP) laser as reference standard methods.
DOI: 10.1089/end.2007.0421
PubMed: 18377234
Links to Exploration step
pubmed:18377234Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Systematic evaluation of a recently introduced 2-microm continuous-wave thulium laser for vaporesection of the prostate.</title>
<author><name sortKey="Wendt Nordahl, Gunnar" sort="Wendt Nordahl, Gunnar" uniqKey="Wendt Nordahl G" first="Gunnar" last="Wendt-Nordahl">Gunnar Wendt-Nordahl</name>
<affiliation><nlm:affiliation>Department of Urology, University Hospital Mannheim, Mannheim, Germany. gunnar.wendt-nordahl@uro.ma.uni-heidelberg.de</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Huckele, Stephanie" sort="Huckele, Stephanie" uniqKey="Huckele S" first="Stephanie" last="Huckele">Stephanie Huckele</name>
</author>
<author><name sortKey="Honeck, Patrick" sort="Honeck, Patrick" uniqKey="Honeck P" first="Patrick" last="Honeck">Patrick Honeck</name>
</author>
<author><name sortKey="Alken, Peter" sort="Alken, Peter" uniqKey="Alken P" first="Peter" last="Alken">Peter Alken</name>
</author>
<author><name sortKey="Knoll, Thomas" sort="Knoll, Thomas" uniqKey="Knoll T" first="Thomas" last="Knoll">Thomas Knoll</name>
</author>
<author><name sortKey="Michel, Maurice Stephan" sort="Michel, Maurice Stephan" uniqKey="Michel M" first="Maurice Stephan" last="Michel">Maurice Stephan Michel</name>
</author>
<author><name sortKey="H Cker, Axel" sort="H Cker, Axel" uniqKey="H Cker A" first="Axel" last="H Cker">Axel H Cker</name>
</author>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">Systematic evaluation of a recently introduced 2-microm continuous-wave thulium laser for vaporesection of the prostate.</title>
<author><name sortKey="Wendt Nordahl, Gunnar" sort="Wendt Nordahl, Gunnar" uniqKey="Wendt Nordahl G" first="Gunnar" last="Wendt-Nordahl">Gunnar Wendt-Nordahl</name>
<affiliation><nlm:affiliation>Department of Urology, University Hospital Mannheim, Mannheim, Germany. gunnar.wendt-nordahl@uro.ma.uni-heidelberg.de</nlm:affiliation>
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<author><name sortKey="Huckele, Stephanie" sort="Huckele, Stephanie" uniqKey="Huckele S" first="Stephanie" last="Huckele">Stephanie Huckele</name>
</author>
<author><name sortKey="Honeck, Patrick" sort="Honeck, Patrick" uniqKey="Honeck P" first="Patrick" last="Honeck">Patrick Honeck</name>
</author>
<author><name sortKey="Alken, Peter" sort="Alken, Peter" uniqKey="Alken P" first="Peter" last="Alken">Peter Alken</name>
</author>
<author><name sortKey="Knoll, Thomas" sort="Knoll, Thomas" uniqKey="Knoll T" first="Thomas" last="Knoll">Thomas Knoll</name>
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<author><name sortKey="Michel, Maurice Stephan" sort="Michel, Maurice Stephan" uniqKey="Michel M" first="Maurice Stephan" last="Michel">Maurice Stephan Michel</name>
</author>
<author><name sortKey="H Cker, Axel" sort="H Cker, Axel" uniqKey="H Cker A" first="Axel" last="H Cker">Axel H Cker</name>
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<series><title level="j">Journal of endourology / Endourological Society</title>
<idno type="ISSN">0892-7790</idno>
<imprint><date when="2008" type="published">2008</date>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term>
<term>Blood Loss, Surgical</term>
<term>Kidney (blood supply)</term>
<term>Kidney (pathology)</term>
<term>Kidney (surgery)</term>
<term>Laser Therapy</term>
<term>Lasers, Solid-State</term>
<term>Models, Animal</term>
<term>Swine</term>
<term>Thulium</term>
<term>Transurethral Resection of Prostate</term>
</keywords>
<keywords scheme="MESH" type="chemical" xml:lang="en"><term>Thulium</term>
</keywords>
<keywords scheme="MESH" qualifier="blood supply" xml:lang="en"><term>Kidney</term>
</keywords>
<keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Kidney</term>
</keywords>
<keywords scheme="MESH" qualifier="surgery" xml:lang="en"><term>Kidney</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Animals</term>
<term>Blood Loss, Surgical</term>
<term>Laser Therapy</term>
<term>Lasers, Solid-State</term>
<term>Models, Animal</term>
<term>Swine</term>
<term>Transurethral Resection of Prostate</term>
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<front><div type="abstract" xml:lang="en">A novel 2-microm continuous wave (CW) thulium laser device for interventional treatment of benign prostatic hyperplasia was recently introduced into clinical practice and is postulated to have several advantages over more established laser devices. A systematic ex-vivo evaluation of the thulium laser was undertaken to compare the results to transurethral resection of the prostate (TURP) and the potassium-titanyl-phosphate (KTP) laser as reference standard methods.</div>
</front>
</TEI>
<pubmed><MedlineCitation Owner="NLM" Status="MEDLINE"><PMID Version="1">18377234</PMID>
<DateCreated><Year>2008</Year>
<Month>07</Month>
<Day>22</Day>
</DateCreated>
<DateCompleted><Year>2008</Year>
<Month>08</Month>
<Day>14</Day>
</DateCompleted>
<DateRevised><Year>2013</Year>
<Month>11</Month>
<Day>21</Day>
</DateRevised>
<Article PubModel="Print"><Journal><ISSN IssnType="Print">0892-7790</ISSN>
<JournalIssue CitedMedium="Print"><Volume>22</Volume>
<Issue>5</Issue>
<PubDate><Year>2008</Year>
<Month>May</Month>
</PubDate>
</JournalIssue>
<Title>Journal of endourology / Endourological Society</Title>
<ISOAbbreviation>J. Endourol.</ISOAbbreviation>
</Journal>
<ArticleTitle>Systematic evaluation of a recently introduced 2-microm continuous-wave thulium laser for vaporesection of the prostate.</ArticleTitle>
<Pagination><MedlinePgn>1041-5</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1089/end.2007.0421</ELocationID>
<Abstract><AbstractText Label="BACKGROUND AND PURPOSE" NlmCategory="OBJECTIVE">A novel 2-microm continuous wave (CW) thulium laser device for interventional treatment of benign prostatic hyperplasia was recently introduced into clinical practice and is postulated to have several advantages over more established laser devices. A systematic ex-vivo evaluation of the thulium laser was undertaken to compare the results to transurethral resection of the prostate (TURP) and the potassium-titanyl-phosphate (KTP) laser as reference standard methods.</AbstractText>
<AbstractText Label="MATERIALS AND METHODS" NlmCategory="METHODS">The RevoLix CW thulium laser system was evaluated in the well-established model of the isolated blood-perfused porcine kidney to determine its tissue ablation capacity and hemostatic properties at different power settings. Histologic examination of the ablated tissue followed. The results were compared to the reference standards, TURP and 80-W KTP laser.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">At a power setting of 70 W, the CW thulium laser displays a higher tissue ablation rate, reaching 6.56+/-0.69 g after 10 minutes, compared to the 80 W KTP laser (3.99+/-0.48 g; P<0.05). Only 30 seconds were needed to resect tissue with the same surface area using TURP, resulting in 8.28+/-0.38 g of tissue removal. With a bleeding rate of 0.16+/-0.07 g/min, the CW thulium laser offers hemostatic properties equal to those of the KTP laser (0.21+/-0.07 g/min), and a significantly reduced bleeding rate compared to TURP (20.14+/-2.03 g/min; P<0.05). The corresponding depths of the coagulation zones were 264.7+/-41.3 microm for the CW thulium laser, 666.9+/-64.0 microm for the KTP laser (P<0.05), and 287.1+/-27.5 microm for TURP.</AbstractText>
<AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">In this standardized ex-vivo investigation, the 2-microm CW thulium laser offered a higher tissue ablation capacity and similar hemostatic properties as those of the KTP laser, and in comparison to TURP both tissue ablation and the bleeding rate were significantly reduced.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Wendt-Nordahl</LastName>
<ForeName>Gunnar</ForeName>
<Initials>G</Initials>
<AffiliationInfo><Affiliation>Department of Urology, University Hospital Mannheim, Mannheim, Germany. gunnar.wendt-nordahl@uro.ma.uni-heidelberg.de</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Huckele</LastName>
<ForeName>Stephanie</ForeName>
<Initials>S</Initials>
</Author>
<Author ValidYN="Y"><LastName>Honeck</LastName>
<ForeName>Patrick</ForeName>
<Initials>P</Initials>
</Author>
<Author ValidYN="Y"><LastName>Alken</LastName>
<ForeName>Peter</ForeName>
<Initials>P</Initials>
</Author>
<Author ValidYN="Y"><LastName>Knoll</LastName>
<ForeName>Thomas</ForeName>
<Initials>T</Initials>
</Author>
<Author ValidYN="Y"><LastName>Michel</LastName>
<ForeName>Maurice Stephan</ForeName>
<Initials>MS</Initials>
</Author>
<Author ValidYN="Y"><LastName>Häcker</LastName>
<ForeName>Axel</ForeName>
<Initials>A</Initials>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D003160">Comparative Study</PublicationType>
<PublicationType UI="D016428">Journal Article</PublicationType>
</PublicationTypeList>
</Article>
<MedlineJournalInfo><Country>United States</Country>
<MedlineTA>J Endourol</MedlineTA>
<NlmUniqueID>8807503</NlmUniqueID>
<ISSNLinking>0892-7790</ISSNLinking>
</MedlineJournalInfo>
<ChemicalList><Chemical><RegistryNumber>8RKC5ATI4P</RegistryNumber>
<NameOfSubstance UI="D013932">Thulium</NameOfSubstance>
</Chemical>
</ChemicalList>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName MajorTopicYN="N" UI="D000818">Animals</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D016063">Blood Loss, Surgical</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D007668">Kidney</DescriptorName>
<QualifierName MajorTopicYN="N" UI="Q000098">blood supply</QualifierName>
<QualifierName MajorTopicYN="N" UI="Q000473">pathology</QualifierName>
<QualifierName MajorTopicYN="Y" UI="Q000601">surgery</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="Y" UI="D053685">Laser Therapy</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D053844">Lasers, Solid-State</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D023421">Models, Animal</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D013552">Swine</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="Y" UI="D013932">Thulium</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D020728">Transurethral Resection of Prostate</DescriptorName>
</MeshHeading>
</MeshHeadingList>
</MedlineCitation>
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