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Percutaneous aortic valve replacement: endovascular resection of human aortic valves in situ.

Identifieur interne : 000584 ( PubMed/Corpus ); précédent : 000583; suivant : 000585

Percutaneous aortic valve replacement: endovascular resection of human aortic valves in situ.

Auteurs : René Quaden ; Tim Attmann ; Michael Schünke ; Dirk Theisen-Kunde ; Jochen Cremer ; Georg Lutter

Source :

RBID : pubmed:18455588

English descriptors

Abstract

Transluminal in vitro resection of severely calcified human aortic valves has already been successfully carried out by our group. The aim of this study was to analyze endovascular laser-assisted resection of human aortic valves in situ in 10 human cadavers.

DOI: 10.1016/j.jtcvs.2007.11.036
PubMed: 18455588

Links to Exploration step

pubmed:18455588

Le document en format XML

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<title xml:lang="en">Percutaneous aortic valve replacement: endovascular resection of human aortic valves in situ.</title>
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<name sortKey="Quaden, Rene" sort="Quaden, Rene" uniqKey="Quaden R" first="René" last="Quaden">René Quaden</name>
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<nlm:affiliation>Department of Cardiovascular Surgery, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany.</nlm:affiliation>
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<name sortKey="Attmann, Tim" sort="Attmann, Tim" uniqKey="Attmann T" first="Tim" last="Attmann">Tim Attmann</name>
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<name sortKey="Schunke, Michael" sort="Schunke, Michael" uniqKey="Schunke M" first="Michael" last="Schünke">Michael Schünke</name>
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<name sortKey="Theisen Kunde, Dirk" sort="Theisen Kunde, Dirk" uniqKey="Theisen Kunde D" first="Dirk" last="Theisen-Kunde">Dirk Theisen-Kunde</name>
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<name sortKey="Cremer, Jochen" sort="Cremer, Jochen" uniqKey="Cremer J" first="Jochen" last="Cremer">Jochen Cremer</name>
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<name sortKey="Lutter, Georg" sort="Lutter, Georg" uniqKey="Lutter G" first="Georg" last="Lutter">Georg Lutter</name>
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<title xml:lang="en">Percutaneous aortic valve replacement: endovascular resection of human aortic valves in situ.</title>
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<name sortKey="Quaden, Rene" sort="Quaden, Rene" uniqKey="Quaden R" first="René" last="Quaden">René Quaden</name>
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<nlm:affiliation>Department of Cardiovascular Surgery, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany.</nlm:affiliation>
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<name sortKey="Attmann, Tim" sort="Attmann, Tim" uniqKey="Attmann T" first="Tim" last="Attmann">Tim Attmann</name>
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<name sortKey="Schunke, Michael" sort="Schunke, Michael" uniqKey="Schunke M" first="Michael" last="Schünke">Michael Schünke</name>
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<name sortKey="Theisen Kunde, Dirk" sort="Theisen Kunde, Dirk" uniqKey="Theisen Kunde D" first="Dirk" last="Theisen-Kunde">Dirk Theisen-Kunde</name>
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<name sortKey="Cremer, Jochen" sort="Cremer, Jochen" uniqKey="Cremer J" first="Jochen" last="Cremer">Jochen Cremer</name>
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<name sortKey="Lutter, Georg" sort="Lutter, Georg" uniqKey="Lutter G" first="Georg" last="Lutter">Georg Lutter</name>
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<title level="j">The Journal of thoracic and cardiovascular surgery</title>
<idno type="eISSN">1097-685X</idno>
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<date when="2008" type="published">2008</date>
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<term>Aortic Valve (surgery)</term>
<term>Cadaver</term>
<term>Calcinosis (surgery)</term>
<term>Endoscopy</term>
<term>Feasibility Studies</term>
<term>Heart Valve Diseases (surgery)</term>
<term>Humans</term>
<term>Laser Therapy</term>
</keywords>
<keywords scheme="MESH" qualifier="surgery" xml:lang="en">
<term>Aortic Valve</term>
<term>Calcinosis</term>
<term>Heart Valve Diseases</term>
</keywords>
<keywords scheme="MESH" xml:lang="en">
<term>Cadaver</term>
<term>Endoscopy</term>
<term>Feasibility Studies</term>
<term>Humans</term>
<term>Laser Therapy</term>
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<div type="abstract" xml:lang="en">Transluminal in vitro resection of severely calcified human aortic valves has already been successfully carried out by our group. The aim of this study was to analyze endovascular laser-assisted resection of human aortic valves in situ in 10 human cadavers.</div>
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<DateCreated>
<Year>2008</Year>
<Month>05</Month>
<Day>05</Day>
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<DateCompleted>
<Year>2008</Year>
<Month>06</Month>
<Day>03</Day>
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<Article PubModel="Print">
<Journal>
<ISSN IssnType="Electronic">1097-685X</ISSN>
<JournalIssue CitedMedium="Internet">
<Volume>135</Volume>
<Issue>5</Issue>
<PubDate>
<Year>2008</Year>
<Month>May</Month>
</PubDate>
</JournalIssue>
<Title>The Journal of thoracic and cardiovascular surgery</Title>
<ISOAbbreviation>J. Thorac. Cardiovasc. Surg.</ISOAbbreviation>
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<ArticleTitle>Percutaneous aortic valve replacement: endovascular resection of human aortic valves in situ.</ArticleTitle>
<Pagination>
<MedlinePgn>1081-6</MedlinePgn>
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<ELocationID EIdType="doi" ValidYN="Y">10.1016/j.jtcvs.2007.11.036</ELocationID>
<Abstract>
<AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">Transluminal in vitro resection of severely calcified human aortic valves has already been successfully carried out by our group. The aim of this study was to analyze endovascular laser-assisted resection of human aortic valves in situ in 10 human cadavers.</AbstractText>
<AbstractText Label="MATERIAL AND METHODS" NlmCategory="METHODS">After anterolateral minithoracotomy, the aortic valve isolation chamber system was inserted into the descending aorta and pushed forward transluminally into the aortic position to generate a separate operation space between the subvalvular and the proximal ascending aortic area. After deployment and sealing of the chamber, stable function with a continuous chamber lavage of 1.58 L/min saline solution was established (8/10 cases). The endoscopically guided laser fiber was delivered via the right carotid artery. After fixation of a leaflet by a forceps catheter, the native leaflets were resected each by a thulium:YAG laser with 20-W power rating. Macropathology and micropathology of surrounding anatomic structures were analyzed.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">The duration of transluminal positioning and deployment of the aortic valve isolation chamber took 7.3 +/- 5.8 minutes. Fluoroscopy confirmed sealed chambers. The resection was completed in all leaflets and took, on average, 6.0 +/- 3.5 minutes per leaflet. The aortic wall was moderately injured in 4 of 10 cases and the aortic annulus in two cases with one aortic wall perforation. The surrounding tissue, the coronary ostia, the mitral valve, and the left ventricular outflow tract remained unaffected.</AbstractText>
<AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">This study demonstrates the feasibility of endovascular resection of human aortic valves in situ. This is a subsequent step toward complete percutaneous replacement (resection and implantation) of human aortic valves.</AbstractText>
</Abstract>
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<LastName>Quaden</LastName>
<ForeName>René</ForeName>
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<Affiliation>Department of Cardiovascular Surgery, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany.</Affiliation>
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<DescriptorName MajorTopicYN="N" UI="D001021">Aortic Valve</DescriptorName>
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<Month>5</Month>
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<Year>2007</Year>
<Month>8</Month>
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<Year>2007</Year>
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