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Tm:YAG laser en bloc mucosectomy for accurate staging of primary bladder cancer: early experience.

Identifieur interne : 000438 ( PubMed/Corpus ); précédent : 000437; suivant : 000439

Tm:YAG laser en bloc mucosectomy for accurate staging of primary bladder cancer: early experience.

Auteurs : Mathias Wolters ; Mario W. Kramer ; Jan U. Becker ; Matthias Christgen ; Udo Nagele ; Florian Imkamp ; Martin Burchardt ; Axel S. Merseburger ; Markus A. Kuczyk ; Thorsten Bach ; Andreas J. Gross ; Thomas R W. Herrmann

Source :

RBID : pubmed:21553277

English descriptors

Abstract

Exact pathological staging of bladder cancer is crucial for determination of further treatment. One limiting factor is the surgical 'incise and scatter' technique that might contribute to tumour recurrence. En bloc resection techniques are en emerging issue. We present initial results with Thulium:YAG (Tm:YAG) en bloc resection of bladder tumours for treatment and accurate staging of solitary transitional cell carcinoma of the bladder.

DOI: 10.1007/s00345-011-0686-z
PubMed: 21553277

Links to Exploration step

pubmed:21553277

Le document en format XML

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<title xml:lang="en">Tm:YAG laser en bloc mucosectomy for accurate staging of primary bladder cancer: early experience.</title>
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<name sortKey="Wolters, Mathias" sort="Wolters, Mathias" uniqKey="Wolters M" first="Mathias" last="Wolters">Mathias Wolters</name>
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<nlm:affiliation>Department of Urology and Urological Oncology, Hannover Medical School (MHH), Carl Neuberg Str. 1, 30625, Hannover, Germany.</nlm:affiliation>
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<name sortKey="Kramer, Mario W" sort="Kramer, Mario W" uniqKey="Kramer M" first="Mario W" last="Kramer">Mario W. Kramer</name>
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<name sortKey="Becker, Jan U" sort="Becker, Jan U" uniqKey="Becker J" first="Jan U" last="Becker">Jan U. Becker</name>
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<name sortKey="Christgen, Matthias" sort="Christgen, Matthias" uniqKey="Christgen M" first="Matthias" last="Christgen">Matthias Christgen</name>
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<name sortKey="Nagele, Udo" sort="Nagele, Udo" uniqKey="Nagele U" first="Udo" last="Nagele">Udo Nagele</name>
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<name sortKey="Imkamp, Florian" sort="Imkamp, Florian" uniqKey="Imkamp F" first="Florian" last="Imkamp">Florian Imkamp</name>
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<name sortKey="Burchardt, Martin" sort="Burchardt, Martin" uniqKey="Burchardt M" first="Martin" last="Burchardt">Martin Burchardt</name>
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<name sortKey="Merseburger, Axel S" sort="Merseburger, Axel S" uniqKey="Merseburger A" first="Axel S" last="Merseburger">Axel S. Merseburger</name>
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<name sortKey="Kuczyk, Markus A" sort="Kuczyk, Markus A" uniqKey="Kuczyk M" first="Markus A" last="Kuczyk">Markus A. Kuczyk</name>
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<name sortKey="Bach, Thorsten" sort="Bach, Thorsten" uniqKey="Bach T" first="Thorsten" last="Bach">Thorsten Bach</name>
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<name sortKey="Gross, Andreas J" sort="Gross, Andreas J" uniqKey="Gross A" first="Andreas J" last="Gross">Andreas J. Gross</name>
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<name sortKey="Herrmann, Thomas R W" sort="Herrmann, Thomas R W" uniqKey="Herrmann T" first="Thomas R W" last="Herrmann">Thomas R W. Herrmann</name>
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<name sortKey="Kramer, Mario W" sort="Kramer, Mario W" uniqKey="Kramer M" first="Mario W" last="Kramer">Mario W. Kramer</name>
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<name sortKey="Christgen, Matthias" sort="Christgen, Matthias" uniqKey="Christgen M" first="Matthias" last="Christgen">Matthias Christgen</name>
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<name sortKey="Nagele, Udo" sort="Nagele, Udo" uniqKey="Nagele U" first="Udo" last="Nagele">Udo Nagele</name>
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<name sortKey="Imkamp, Florian" sort="Imkamp, Florian" uniqKey="Imkamp F" first="Florian" last="Imkamp">Florian Imkamp</name>
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<name sortKey="Burchardt, Martin" sort="Burchardt, Martin" uniqKey="Burchardt M" first="Martin" last="Burchardt">Martin Burchardt</name>
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<name sortKey="Merseburger, Axel S" sort="Merseburger, Axel S" uniqKey="Merseburger A" first="Axel S" last="Merseburger">Axel S. Merseburger</name>
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<name sortKey="Kuczyk, Markus A" sort="Kuczyk, Markus A" uniqKey="Kuczyk M" first="Markus A" last="Kuczyk">Markus A. Kuczyk</name>
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<name sortKey="Bach, Thorsten" sort="Bach, Thorsten" uniqKey="Bach T" first="Thorsten" last="Bach">Thorsten Bach</name>
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<name sortKey="Gross, Andreas J" sort="Gross, Andreas J" uniqKey="Gross A" first="Andreas J" last="Gross">Andreas J. Gross</name>
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<name sortKey="Herrmann, Thomas R W" sort="Herrmann, Thomas R W" uniqKey="Herrmann T" first="Thomas R W" last="Herrmann">Thomas R W. Herrmann</name>
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<series>
<title level="j">World journal of urology</title>
<idno type="eISSN">1433-8726</idno>
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<date when="2011" type="published">2011</date>
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<term>Aged</term>
<term>Aged, 80 and over</term>
<term>Carcinoma, Transitional Cell (pathology)</term>
<term>Carcinoma, Transitional Cell (surgery)</term>
<term>Female</term>
<term>Humans</term>
<term>Lasers, Solid-State (adverse effects)</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Mucous Membrane (pathology)</term>
<term>Mucous Membrane (surgery)</term>
<term>Neoplasm Staging</term>
<term>Retrospective Studies</term>
<term>Sensitivity and Specificity</term>
<term>Thulium (adverse effects)</term>
<term>Urinary Bladder (pathology)</term>
<term>Urinary Bladder (surgery)</term>
<term>Urinary Bladder Neoplasms (pathology)</term>
<term>Urinary Bladder Neoplasms (surgery)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="adverse effects" xml:lang="en">
<term>Thulium</term>
</keywords>
<keywords scheme="MESH" qualifier="adverse effects" xml:lang="en">
<term>Lasers, Solid-State</term>
</keywords>
<keywords scheme="MESH" qualifier="pathology" xml:lang="en">
<term>Carcinoma, Transitional Cell</term>
<term>Mucous Membrane</term>
<term>Urinary Bladder</term>
<term>Urinary Bladder Neoplasms</term>
</keywords>
<keywords scheme="MESH" qualifier="surgery" xml:lang="en">
<term>Carcinoma, Transitional Cell</term>
<term>Mucous Membrane</term>
<term>Urinary Bladder</term>
<term>Urinary Bladder Neoplasms</term>
</keywords>
<keywords scheme="MESH" xml:lang="en">
<term>Aged</term>
<term>Aged, 80 and over</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Neoplasm Staging</term>
<term>Retrospective Studies</term>
<term>Sensitivity and Specificity</term>
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<front>
<div type="abstract" xml:lang="en">Exact pathological staging of bladder cancer is crucial for determination of further treatment. One limiting factor is the surgical 'incise and scatter' technique that might contribute to tumour recurrence. En bloc resection techniques are en emerging issue. We present initial results with Thulium:YAG (Tm:YAG) en bloc resection of bladder tumours for treatment and accurate staging of solitary transitional cell carcinoma of the bladder.</div>
</front>
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<PMID Version="1">21553277</PMID>
<DateCreated>
<Year>2011</Year>
<Month>07</Month>
<Day>26</Day>
</DateCreated>
<DateCompleted>
<Year>2012</Year>
<Month>01</Month>
<Day>03</Day>
</DateCompleted>
<DateRevised>
<Year>2013</Year>
<Month>11</Month>
<Day>21</Day>
</DateRevised>
<Article PubModel="Print-Electronic">
<Journal>
<ISSN IssnType="Electronic">1433-8726</ISSN>
<JournalIssue CitedMedium="Internet">
<Volume>29</Volume>
<Issue>4</Issue>
<PubDate>
<Year>2011</Year>
<Month>Aug</Month>
</PubDate>
</JournalIssue>
<Title>World journal of urology</Title>
<ISOAbbreviation>World J Urol</ISOAbbreviation>
</Journal>
<ArticleTitle>Tm:YAG laser en bloc mucosectomy for accurate staging of primary bladder cancer: early experience.</ArticleTitle>
<Pagination>
<MedlinePgn>429-32</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1007/s00345-011-0686-z</ELocationID>
<Abstract>
<AbstractText Label="INTRODUCTION" NlmCategory="BACKGROUND">Exact pathological staging of bladder cancer is crucial for determination of further treatment. One limiting factor is the surgical 'incise and scatter' technique that might contribute to tumour recurrence. En bloc resection techniques are en emerging issue. We present initial results with Thulium:YAG (Tm:YAG) en bloc resection of bladder tumours for treatment and accurate staging of solitary transitional cell carcinoma of the bladder.</AbstractText>
<AbstractText Label="MATERIALS AND METHODS" NlmCategory="METHODS">From June through October 2010, six patients were treated by TmLRBT (Thulium laser resection of bladder tumour). Inclusion criteria were solitary lesions, treatment naive patients and tumour localisation of the lower bladder wall and trigonum. En bloc resection was applied on all of the tumours. Two cold-cut biopsies from the tumour base were extracted. On five of the six patients, a re-resection was performed after 6 weeks.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">Pathological evaluation revealed 1 patient with pTa G1, 2 patients with pTa G2 and 3 patients with pT1 G3. All of the resected specimens provided detrusor muscle, and all biopsies were positive for muscle cells. No intra-, peri- or post-operative complications were observed. Bladder irrigation was mandatory in only 50% of the patients. All patients were negative for residual TCC in re-resection 6 weeks after initial treatment.</AbstractText>
<AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">TmLRBT has been proven safe and effective for both, treatment and pathological staging of primary TCC of the bladder. Tm:YAG en bloc resection therefore could be an appropriate tool for accurate staging with possibly lower scattering potential for the assessment and treatment of patients with TCC.</AbstractText>
</Abstract>
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<DescriptorName MajorTopicYN="Y" UI="D053844">Lasers, Solid-State</DescriptorName>
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<DescriptorName MajorTopicYN="Y" UI="D013932">Thulium</DescriptorName>
<QualifierName MajorTopicYN="N" UI="Q000009">adverse effects</QualifierName>
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<MeshHeading>
<DescriptorName MajorTopicYN="N" UI="D001743">Urinary Bladder</DescriptorName>
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<QualifierName MajorTopicYN="N" UI="Q000601">surgery</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName MajorTopicYN="N" UI="D001749">Urinary Bladder Neoplasms</DescriptorName>
<QualifierName MajorTopicYN="Y" UI="Q000473">pathology</QualifierName>
<QualifierName MajorTopicYN="N" UI="Q000601">surgery</QualifierName>
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<Year>2011</Year>
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