Hydrothermal synthesis of NaLuF4:153Sm,Yb,Tm nanoparticles and their application in dual-modality upconversion luminescence and SPECT bioimaging.
Identifieur interne : 000329 ( PubMed/Corpus ); précédent : 000328; suivant : 000330Hydrothermal synthesis of NaLuF4:153Sm,Yb,Tm nanoparticles and their application in dual-modality upconversion luminescence and SPECT bioimaging.
Auteurs : Yang Yang ; Yun Sun ; Tianye Cao ; Juanjuan Peng ; Ying Liu ; Yongquan Wu ; Wei Feng ; Yingjian Zhang ; Fuyou LiSource :
- Biomaterials [ 1878-5905 ] ; 2013.
English descriptors
- KwdEn :
- Animals, Cell Line, Tumor, Fluorine Compounds (chemistry), Fluorine Compounds (pharmacokinetics), Fluorine Compounds (toxicity), Humans, Luminescence, Luminescent Measurements (methods), Lutetium (chemistry), Lutetium (pharmacokinetics), Lutetium (toxicity), Mice, Nanoparticles (analysis), Nanoparticles (toxicity), Nanoparticles (ultrastructure), Optical Imaging (methods), Radioisotopes (chemistry), Radioisotopes (pharmacokinetics), Radioisotopes (toxicity), Samarium (chemistry), Samarium (pharmacokinetics), Samarium (toxicity), Sodium (chemistry), Sodium (pharmacokinetics), Sodium (toxicity), Thulium (chemistry), Thulium (pharmacokinetics), Thulium (toxicity), Tissue Distribution, Tomography, Emission-Computed, Single-Photon (methods), Ytterbium (chemistry), Ytterbium (pharmacokinetics), Ytterbium (toxicity).
- MESH :
- chemical , chemistry : Fluorine Compounds, Lutetium, Radioisotopes, Samarium, Sodium, Thulium, Ytterbium.
- chemical , pharmacokinetics : Fluorine Compounds, Lutetium, Radioisotopes, Samarium, Sodium, Thulium, Ytterbium.
- chemical , toxicity : Fluorine Compounds, Lutetium, Radioisotopes, Samarium, Sodium, Thulium, Ytterbium.
- analysis : Nanoparticles.
- methods : Luminescent Measurements, Optical Imaging, Tomography, Emission-Computed, Single-Photon.
- toxicity : Nanoparticles.
- ultrastructure : Nanoparticles.
- Animals, Cell Line, Tumor, Humans, Luminescence, Mice, Tissue Distribution.
Abstract
Upconversion luminescence (UCL) properties and radioactivity have been integrated into NaLuF(4):(153)Sm,Yb,Tm nanoparticles by a facile one-step hydrothermal method, making these nanoparticles potential candidates for UCL and single-photon emission computed tomography (SPECT) dual-modal bioimaging in vivo. The introduction of small amount of radioactive (153)Sm(3+) can hardly vary the upconversion luminescence properties of the nanoparticles. The as-designed nanoparticles showed very low cytotoxicity, no obvious tissue damage in 7 days, and excellent in vitro and in vivo performances in dual-modal bioimaging. By means of a combination of UCL and SPECT imaging in vivo, the distribution of the nanoparticles in living animals has been studied, and the results indicated that these particles were mainly accumulated in the liver and spleen. Therefore, the concept of (153)Sm(3+)/Yb(3+)/Tm(3+) co-doped NaLuF(4) nanoparticles for UCL and SPECT dual-modality imaging in vivo of whole-body animals may serve as a platform for next-generation probes for ultra-sensitive molecular imaging from the cellular scale to whole-body evaluation. It also introduces an easy methodology to quantify in vivo biodistribution of nanomaterials which still needs further understanding as a community.
DOI: 10.1016/j.biomaterials.2012.10.022
PubMed: 23117216
Links to Exploration step
pubmed:23117216Le document en format XML
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Liu</name></author><author><name sortKey="Wu, Yongquan" sort="Wu, Yongquan" uniqKey="Wu Y" first="Yongquan" last="Wu">Yongquan Wu</name></author><author><name sortKey="Feng, Wei" sort="Feng, Wei" uniqKey="Feng W" first="Wei" last="Feng">Wei Feng</name></author><author><name sortKey="Zhang, Yingjian" sort="Zhang, Yingjian" uniqKey="Zhang Y" first="Yingjian" last="Zhang">Yingjian Zhang</name></author><author><name sortKey="Li, Fuyou" sort="Li, Fuyou" uniqKey="Li F" first="Fuyou" last="Li">Fuyou Li</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2013">2013</date><idno type="doi">10.1016/j.biomaterials.2012.10.022</idno><idno type="RBID">pubmed:23117216</idno><idno type="pmid">23117216</idno><idno type="wicri:Area/PubMed/Corpus">000329</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000329</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Hydrothermal synthesis of NaLuF4:153Sm,Yb,Tm nanoparticles and their application in dual-modality upconversion luminescence and SPECT bioimaging.</title><author><name sortKey="Yang, Yang" sort="Yang, Yang" uniqKey="Yang Y" first="Yang" last="Yang">Yang Yang</name><affiliation><nlm:affiliation>Department of Chemistry & Institute of Biomedical Science, Fudan University, 220 Handan Road, Shanghai, PR China.</nlm:affiliation></affiliation></author><author><name sortKey="Sun, Yun" sort="Sun, Yun" uniqKey="Sun Y" first="Yun" last="Sun">Yun Sun</name></author><author><name sortKey="Cao, Tianye" sort="Cao, Tianye" uniqKey="Cao T" first="Tianye" last="Cao">Tianye Cao</name></author><author><name sortKey="Peng, Juanjuan" sort="Peng, Juanjuan" uniqKey="Peng J" first="Juanjuan" last="Peng">Juanjuan Peng</name></author><author><name sortKey="Liu, Ying" sort="Liu, Ying" uniqKey="Liu Y" first="Ying" last="Liu">Ying Liu</name></author><author><name sortKey="Wu, Yongquan" sort="Wu, Yongquan" uniqKey="Wu Y" first="Yongquan" last="Wu">Yongquan Wu</name></author><author><name sortKey="Feng, Wei" sort="Feng, Wei" uniqKey="Feng W" first="Wei" last="Feng">Wei Feng</name></author><author><name sortKey="Zhang, Yingjian" sort="Zhang, Yingjian" uniqKey="Zhang Y" first="Yingjian" last="Zhang">Yingjian Zhang</name></author><author><name sortKey="Li, Fuyou" sort="Li, Fuyou" uniqKey="Li F" first="Fuyou" last="Li">Fuyou Li</name></author></analytic><series><title level="j">Biomaterials</title><idno type="eISSN">1878-5905</idno><imprint><date when="2013" type="published">2013</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term><term>Cell Line, Tumor</term><term>Fluorine Compounds (chemistry)</term><term>Fluorine Compounds (pharmacokinetics)</term><term>Fluorine Compounds (toxicity)</term><term>Humans</term><term>Luminescence</term><term>Luminescent Measurements (methods)</term><term>Lutetium (chemistry)</term><term>Lutetium (pharmacokinetics)</term><term>Lutetium (toxicity)</term><term>Mice</term><term>Nanoparticles (analysis)</term><term>Nanoparticles (toxicity)</term><term>Nanoparticles (ultrastructure)</term><term>Optical Imaging (methods)</term><term>Radioisotopes (chemistry)</term><term>Radioisotopes (pharmacokinetics)</term><term>Radioisotopes (toxicity)</term><term>Samarium (chemistry)</term><term>Samarium (pharmacokinetics)</term><term>Samarium (toxicity)</term><term>Sodium (chemistry)</term><term>Sodium (pharmacokinetics)</term><term>Sodium (toxicity)</term><term>Thulium (chemistry)</term><term>Thulium (pharmacokinetics)</term><term>Thulium (toxicity)</term><term>Tissue Distribution</term><term>Tomography, Emission-Computed, Single-Photon (methods)</term><term>Ytterbium (chemistry)</term><term>Ytterbium (pharmacokinetics)</term><term>Ytterbium (toxicity)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="chemistry" xml:lang="en"><term>Fluorine Compounds</term><term>Lutetium</term><term>Radioisotopes</term><term>Samarium</term><term>Sodium</term><term>Thulium</term><term>Ytterbium</term></keywords><keywords scheme="MESH" type="chemical" qualifier="pharmacokinetics" xml:lang="en"><term>Fluorine Compounds</term><term>Lutetium</term><term>Radioisotopes</term><term>Samarium</term><term>Sodium</term><term>Thulium</term><term>Ytterbium</term></keywords><keywords scheme="MESH" type="chemical" qualifier="toxicity" xml:lang="en"><term>Fluorine Compounds</term><term>Lutetium</term><term>Radioisotopes</term><term>Samarium</term><term>Sodium</term><term>Thulium</term><term>Ytterbium</term></keywords><keywords scheme="MESH" qualifier="analysis" xml:lang="en"><term>Nanoparticles</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Luminescent Measurements</term><term>Optical Imaging</term><term>Tomography, Emission-Computed, Single-Photon</term></keywords><keywords scheme="MESH" qualifier="toxicity" xml:lang="en"><term>Nanoparticles</term></keywords><keywords scheme="MESH" qualifier="ultrastructure" xml:lang="en"><term>Nanoparticles</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Cell Line, Tumor</term><term>Humans</term><term>Luminescence</term><term>Mice</term><term>Tissue Distribution</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Upconversion luminescence (UCL) properties and radioactivity have been integrated into NaLuF(4):(153)Sm,Yb,Tm nanoparticles by a facile one-step hydrothermal method, making these nanoparticles potential candidates for UCL and single-photon emission computed tomography (SPECT) dual-modal bioimaging in vivo. The introduction of small amount of radioactive (153)Sm(3+) can hardly vary the upconversion luminescence properties of the nanoparticles. The as-designed nanoparticles showed very low cytotoxicity, no obvious tissue damage in 7 days, and excellent in vitro and in vivo performances in dual-modal bioimaging. By means of a combination of UCL and SPECT imaging in vivo, the distribution of the nanoparticles in living animals has been studied, and the results indicated that these particles were mainly accumulated in the liver and spleen. Therefore, the concept of (153)Sm(3+)/Yb(3+)/Tm(3+) co-doped NaLuF(4) nanoparticles for UCL and SPECT dual-modality imaging in vivo of whole-body animals may serve as a platform for next-generation probes for ultra-sensitive molecular imaging from the cellular scale to whole-body evaluation. It also introduces an easy methodology to quantify in vivo biodistribution of nanomaterials which still needs further understanding as a community.</div></front></TEI><pubmed><MedlineCitation Owner="NLM" Status="MEDLINE"><PMID Version="1">23117216</PMID><DateCreated><Year>2012</Year><Month>11</Month><Day>12</Day></DateCreated><DateCompleted><Year>2013</Year><Month>04</Month><Day>17</Day></DateCompleted><DateRevised><Year>2013</Year><Month>11</Month><Day>21</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1878-5905</ISSN><JournalIssue CitedMedium="Internet"><Volume>34</Volume><Issue>3</Issue><PubDate><Year>2013</Year><Month>Jan</Month></PubDate></JournalIssue><Title>Biomaterials</Title><ISOAbbreviation>Biomaterials</ISOAbbreviation></Journal><ArticleTitle>Hydrothermal synthesis of NaLuF4:153Sm,Yb,Tm nanoparticles and their application in dual-modality upconversion luminescence and SPECT bioimaging.</ArticleTitle><Pagination><MedlinePgn>774-83</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.biomaterials.2012.10.022</ELocationID><ELocationID EIdType="pii" ValidYN="Y">S0142-9612(12)01143-X</ELocationID><Abstract><AbstractText>Upconversion luminescence (UCL) properties and radioactivity have been integrated into NaLuF(4):(153)Sm,Yb,Tm nanoparticles by a facile one-step hydrothermal method, making these nanoparticles potential candidates for UCL and single-photon emission computed tomography (SPECT) dual-modal bioimaging in vivo. The introduction of small amount of radioactive (153)Sm(3+) can hardly vary the upconversion luminescence properties of the nanoparticles. The as-designed nanoparticles showed very low cytotoxicity, no obvious tissue damage in 7 days, and excellent in vitro and in vivo performances in dual-modal bioimaging. By means of a combination of UCL and SPECT imaging in vivo, the distribution of the nanoparticles in living animals has been studied, and the results indicated that these particles were mainly accumulated in the liver and spleen. Therefore, the concept of (153)Sm(3+)/Yb(3+)/Tm(3+) co-doped NaLuF(4) nanoparticles for UCL and SPECT dual-modality imaging in vivo of whole-body animals may serve as a platform for next-generation probes for ultra-sensitive molecular imaging from the cellular scale to whole-body evaluation. It also introduces an easy methodology to quantify in vivo biodistribution of nanomaterials which still needs further understanding as a community.</AbstractText><CopyrightInformation>Copyright © 2012 Elsevier Ltd. All rights reserved.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Yang</LastName><ForeName>Yang</ForeName><Initials>Y</Initials><AffiliationInfo><Affiliation>Department of Chemistry & Institute of Biomedical Science, Fudan University, 220 Handan Road, Shanghai, PR China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sun</LastName><ForeName>Yun</ForeName><Initials>Y</Initials></Author><Author ValidYN="Y"><LastName>Cao</LastName><ForeName>Tianye</ForeName><Initials>T</Initials></Author><Author ValidYN="Y"><LastName>Peng</LastName><ForeName>Juanjuan</ForeName><Initials>J</Initials></Author><Author ValidYN="Y"><LastName>Liu</LastName><ForeName>Ying</ForeName><Initials>Y</Initials></Author><Author ValidYN="Y"><LastName>Wu</LastName><ForeName>Yongquan</ForeName><Initials>Y</Initials></Author><Author ValidYN="Y"><LastName>Feng</LastName><ForeName>Wei</ForeName><Initials>W</Initials></Author><Author ValidYN="Y"><LastName>Zhang</LastName><ForeName>Yingjian</ForeName><Initials>Y</Initials></Author><Author ValidYN="Y"><LastName>Li</LastName><ForeName>Fuyou</ForeName><Initials>F</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2012</Year><Month>10</Month><Day>29</Day></ArticleDate></Article><MedlineJournalInfo><Country>Netherlands</Country><MedlineTA>Biomaterials</MedlineTA><NlmUniqueID>8100316</NlmUniqueID><ISSNLinking>0142-9612</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D017611">Fluorine Compounds</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D011868">Radioisotopes</NameOfSubstance></Chemical><Chemical><RegistryNumber>42OD65L39F</RegistryNumber><NameOfSubstance UI="D012493">Samarium</NameOfSubstance></Chemical><Chemical><RegistryNumber>5H0DOZ21UJ</RegistryNumber><NameOfSubstance UI="D008187">Lutetium</NameOfSubstance></Chemical><Chemical><RegistryNumber>8RKC5ATI4P</RegistryNumber><NameOfSubstance UI="D013932">Thulium</NameOfSubstance></Chemical><Chemical><RegistryNumber>9NEZ333N27</RegistryNumber><NameOfSubstance UI="D012964">Sodium</NameOfSubstance></Chemical><Chemical><RegistryNumber>MNQ4O4WSI1</RegistryNumber><NameOfSubstance UI="D015018">Ytterbium</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName MajorTopicYN="N" UI="D000818">Animals</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D045744">Cell Line, Tumor</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D017611">Fluorine 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UI="Q000737">chemistry</QualifierName><QualifierName MajorTopicYN="N" UI="Q000493">pharmacokinetics</QualifierName><QualifierName MajorTopicYN="N" UI="Q000633">toxicity</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D012964">Sodium</DescriptorName><QualifierName MajorTopicYN="N" UI="Q000737">chemistry</QualifierName><QualifierName MajorTopicYN="N" UI="Q000493">pharmacokinetics</QualifierName><QualifierName MajorTopicYN="N" UI="Q000633">toxicity</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D013932">Thulium</DescriptorName><QualifierName MajorTopicYN="Y" UI="Q000737">chemistry</QualifierName><QualifierName MajorTopicYN="N" UI="Q000493">pharmacokinetics</QualifierName><QualifierName MajorTopicYN="N" UI="Q000633">toxicity</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D014018">Tissue Distribution</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D015899">Tomography, Emission-Computed, Single-Photon</DescriptorName><QualifierName MajorTopicYN="Y" UI="Q000379">methods</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D015018">Ytterbium</DescriptorName><QualifierName MajorTopicYN="Y" UI="Q000737">chemistry</QualifierName><QualifierName MajorTopicYN="N" UI="Q000493">pharmacokinetics</QualifierName><QualifierName MajorTopicYN="N" UI="Q000633">toxicity</QualifierName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2012</Year><Month>8</Month><Day>9</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2012</Year><Month>10</Month><Day>7</Day></PubMedPubDate><PubMedPubDate PubStatus="aheadofprint"><Year>2012</Year><Month>10</Month><Day>29</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2012</Year><Month>11</Month><Day>3</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2012</Year><Month>11</Month><Day>3</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2013</Year><Month>4</Month><Day>18</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pii">S0142-9612(12)01143-X</ArticleId><ArticleId IdType="doi">10.1016/j.biomaterials.2012.10.022</ArticleId><ArticleId IdType="pubmed">23117216</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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