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Laser treatments of the prostate vs TURP/ open prostatectomy: systematic review of urodynamic data.

Identifieur interne : 000518 ( PubMed/Checkpoint ); précédent : 000517; suivant : 000519

Laser treatments of the prostate vs TURP/ open prostatectomy: systematic review of urodynamic data.

Auteurs : T R W. Herrmann [Allemagne] ; A. Georgiou ; T. Bach ; A J Gross ; M. Oelke

Source :

RBID : pubmed:19773731

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English descriptors

Abstract

Bladder outlet obstruction (BOO) is believed to be the major component of benign prostatic hyperplasia (BPH) that harms the urinary tract. Therefore, BOO relief is the primary treatment objective in patients with obstructive BPH. This systematic review aims to analyze urodynamic data of laser treatment modalities of the prostate in direct comparison with standard treatment (TURP or open prostatectomy). We systematically searched the literature for randomized-controlled trials (RCTs) of prostate laser treatments in which urodynamic results were compared to TURP or open prostatectomy. The literature search included articles that were published between January 1995 and January 2009. Thirty five RCTs were identified encompassing in total 3669 patients. Of all available laser treatments, only one RCT used pressure-flow data to compare the laser treatment of the prostate (holmium laser enucleation, HoLEP) with standard treatment. Improvement of maximum urinary flow rate (Q(max)) of free uroflowmetry was similar for contact laser ablation (CLAP) with Nd:YAG, interstitial laser coagulation with Nd:YAG, potassium potassium-titanyl-phosphate (KTP)/Nd: YAG hybrid treatment, and HoLEP. Qmax improvement was also similar for holmium laser ablation (HoLAP) with 60-80 Watts, holmium laser resection, and thulium laser resection but limited to only one study each. The laser hybrid therapy with CLAP/visual laser ablation of the prostate (VLAP)/Nd:YAG was inferior to TURP. VLAP and KTP showed inhomogeneous

PubMed: 19773731


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<term>Male</term>
<term>Prostatectomy</term>
<term>Prostatic Hyperplasia (complications)</term>
<term>Prostatic Hyperplasia (physiopathology)</term>
<term>Prostatic Hyperplasia (surgery)</term>
<term>Randomized Controlled Trials as Topic</term>
<term>Transurethral Resection of Prostate</term>
<term>Urinary Bladder Neck Obstruction (etiology)</term>
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<term>Coagulation par laser</term>
<term>Essais contrôlés randomisés comme sujet</term>
<term>Humains</term>
<term>Hyperplasie de la prostate ()</term>
<term>Hyperplasie de la prostate (physiopathologie)</term>
<term>Mâle</term>
<term>Obstruction du col de la vessie (physiopathologie)</term>
<term>Obstruction du col de la vessie (étiologie)</term>
<term>Prostatectomie</term>
<term>Résection transuréthrale de prostate</term>
<term>Thérapie laser</term>
<term>Urodynamique</term>
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<term>Prostatic Hyperplasia</term>
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<front>
<div type="abstract" xml:lang="en">Bladder outlet obstruction (BOO) is believed to be the major component of benign prostatic hyperplasia (BPH) that harms the urinary tract. Therefore, BOO relief is the primary treatment objective in patients with obstructive BPH. This systematic review aims to analyze urodynamic data of laser treatment modalities of the prostate in direct comparison with standard treatment (TURP or open prostatectomy). We systematically searched the literature for randomized-controlled trials (RCTs) of prostate laser treatments in which urodynamic results were compared to TURP or open prostatectomy. The literature search included articles that were published between January 1995 and January 2009. Thirty five RCTs were identified encompassing in total 3669 patients. Of all available laser treatments, only one RCT used pressure-flow data to compare the laser treatment of the prostate (holmium laser enucleation, HoLEP) with standard treatment. Improvement of maximum urinary flow rate (Q(max)) of free uroflowmetry was similar for contact laser ablation (CLAP) with Nd:YAG, interstitial laser coagulation with Nd:YAG, potassium potassium-titanyl-phosphate (KTP)/Nd: YAG hybrid treatment, and HoLEP. Qmax improvement was also similar for holmium laser ablation (HoLAP) with 60-80 Watts, holmium laser resection, and thulium laser resection but limited to only one study each. The laser hybrid therapy with CLAP/visual laser ablation of the prostate (VLAP)/Nd:YAG was inferior to TURP. VLAP and KTP showed inhomogeneous</div>
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<Month>05</Month>
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<Title>Minerva urologica e nefrologica = The Italian journal of urology and nephrology</Title>
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<Abstract>
<AbstractText Label="UNLABELLED">Bladder outlet obstruction (BOO) is believed to be the major component of benign prostatic hyperplasia (BPH) that harms the urinary tract. Therefore, BOO relief is the primary treatment objective in patients with obstructive BPH. This systematic review aims to analyze urodynamic data of laser treatment modalities of the prostate in direct comparison with standard treatment (TURP or open prostatectomy). We systematically searched the literature for randomized-controlled trials (RCTs) of prostate laser treatments in which urodynamic results were compared to TURP or open prostatectomy. The literature search included articles that were published between January 1995 and January 2009. Thirty five RCTs were identified encompassing in total 3669 patients. Of all available laser treatments, only one RCT used pressure-flow data to compare the laser treatment of the prostate (holmium laser enucleation, HoLEP) with standard treatment. Improvement of maximum urinary flow rate (Q(max)) of free uroflowmetry was similar for contact laser ablation (CLAP) with Nd:YAG, interstitial laser coagulation with Nd:YAG, potassium potassium-titanyl-phosphate (KTP)/Nd: YAG hybrid treatment, and HoLEP. Qmax improvement was also similar for holmium laser ablation (HoLAP) with 60-80 Watts, holmium laser resection, and thulium laser resection but limited to only one study each. The laser hybrid therapy with CLAP/visual laser ablation of the prostate (VLAP)/Nd:YAG was inferior to TURP. VLAP and KTP showed inhomogeneous</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">Most contemporary laser treatments modalities provide similar Qmax improvement compared to standard treatment. However, precise differences can only be determined by comparative computer urodynamic investigations. Therefore, new laser techniques (such as thulium laser vapoenucleation of the prostate) should be investigated by urodynamic studies in the future.</AbstractText>
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