The safety and efficacy of aspirin intake in photoselective vaporization laser treatment of benign prostate hyperplasia
Identifieur interne : 000360 ( Pmc/Curation ); précédent : 000359; suivant : 000361The safety and efficacy of aspirin intake in photoselective vaporization laser treatment of benign prostate hyperplasia
Auteurs : I-Hung Shao ; Chen-Pang Hou ; Shao-Ming Chen [République populaire de Chine] ; Chien-Lun Chen ; Yu-Hsiang Lin ; Phei-Lang Chang ; Ke-Hung TsuiSource :
- Clinical Interventions in Aging [ 1176-9092 ] ; 2013.
Abstract
Endoscopic surgical treatment has become an option to treat benign prostate hyperplasia. We
evaluated the safety and effectiveness of photoselective vaporization of the prostate (PVP) in
patients. We evaluated preoperative and perioperative parameters, functional outcomes, and adverse
events up to 12 months postoperatively of patients on oral anticoagulation therapy undergoing PVP,
and compared the results with patients who did not take anticoagulation therapy. A total of 89
patients who received photoselective vaporization laser for benign prostate hyperplasia from May
2006 to February 2011 in our hospital were enrolled in our study. The patients were divided into two
groups based on whether or not they were taking oral aspirin; 23 (25.8%) patients were
taking aspirin derivatives (aspirin group), and 66 (74.2%) were not taking aspirin
derivatives (control group). The mean prostate volume (58.8 mL vs 51 mL;
Url:
DOI: 10.2147/CIA.S41270
PubMed: 23662050
PubMed Central: 3646392
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I-Hung Shao<affiliation><nlm:aff id="af1-cia-8-265">Department of Urology, Chang Gung Memorial Hospital-Linko and Chang Gung University College of Medicine</nlm:aff>
<wicri:noCountry code="subfield">Chang Gung Memorial Hospital-Linko and Chang Gung University College of Medicine</wicri:noCountry>
</affiliation>
<affiliation><nlm:aff id="af1-cia-8-265">Department of Urology, Chang Gung Memorial Hospital-Linko and Chang Gung University College of Medicine</nlm:aff>
<wicri:noCountry code="subfield">Chang Gung Memorial Hospital-Linko and Chang Gung University College of Medicine</wicri:noCountry>
</affiliation>
<affiliation><nlm:aff id="af1-cia-8-265">Department of Urology, Chang Gung Memorial Hospital-Linko and Chang Gung University College of Medicine</nlm:aff>
<wicri:noCountry code="subfield">Chang Gung Memorial Hospital-Linko and Chang Gung University College of Medicine</wicri:noCountry>
</affiliation>
<affiliation><nlm:aff id="af2-cia-8-265">Bioinformation Center, Chang Gung Memorial Hospital-Linko and Chang Gung University College of Medicine</nlm:aff>
<wicri:noCountry code="subfield">Chang Gung Memorial Hospital-Linko and Chang Gung University College of Medicine</wicri:noCountry>
</affiliation>
<affiliation><nlm:aff id="af2-cia-8-265">Bioinformation Center, Chang Gung Memorial Hospital-Linko and Chang Gung University College of Medicine</nlm:aff>
<wicri:noCountry code="subfield">Chang Gung Memorial Hospital-Linko and Chang Gung University College of Medicine</wicri:noCountry>
</affiliation>
<affiliation><nlm:aff id="af1-cia-8-265">Department of Urology, Chang Gung Memorial Hospital-Linko and Chang Gung University College of Medicine</nlm:aff>
<wicri:noCountry code="subfield">Chang Gung Memorial Hospital-Linko and Chang Gung University College of Medicine</wicri:noCountry>
</affiliation>
<affiliation><nlm:aff id="af1-cia-8-265">Department of Urology, Chang Gung Memorial Hospital-Linko and Chang Gung University College of Medicine</nlm:aff>
<wicri:noCountry code="subfield">Chang Gung Memorial Hospital-Linko and Chang Gung University College of Medicine</wicri:noCountry>
</affiliation>
<affiliation><nlm:aff id="af2-cia-8-265">Bioinformation Center, Chang Gung Memorial Hospital-Linko and Chang Gung University College of Medicine</nlm:aff>
<wicri:noCountry code="subfield">Chang Gung Memorial Hospital-Linko and Chang Gung University College of Medicine</wicri:noCountry>
</affiliation>
<affiliation><nlm:aff id="af2-cia-8-265">Bioinformation Center, Chang Gung Memorial Hospital-Linko and Chang Gung University College of Medicine</nlm:aff>
<wicri:noCountry code="subfield">Chang Gung Memorial Hospital-Linko and Chang Gung University College of Medicine</wicri:noCountry>
</affiliation>
<affiliation><nlm:aff id="af1-cia-8-265">Department of Urology, Chang Gung Memorial Hospital-Linko and Chang Gung University College of Medicine</nlm:aff>
<wicri:noCountry code="subfield">Chang Gung Memorial Hospital-Linko and Chang Gung University College of Medicine</wicri:noCountry>
</affiliation>
<affiliation><nlm:aff id="af2-cia-8-265">Bioinformation Center, Chang Gung Memorial Hospital-Linko and Chang Gung University College of Medicine</nlm:aff>
<wicri:noCountry code="subfield">Chang Gung Memorial Hospital-Linko and Chang Gung University College of Medicine</wicri:noCountry>
</affiliation>
<affiliation><nlm:aff id="af2-cia-8-265">Bioinformation Center, Chang Gung Memorial Hospital-Linko and Chang Gung University College of Medicine</nlm:aff>
<wicri:noCountry code="subfield">Chang Gung Memorial Hospital-Linko and Chang Gung University College of Medicine</wicri:noCountry>
</affiliation>
Le document en format XML
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treatment of benign prostate hyperplasia</title>
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<affiliation><nlm:aff id="af1-cia-8-265">Department of Urology, Chang Gung Memorial Hospital-Linko and Chang Gung University College of Medicine</nlm:aff>
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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">The safety and efficacy of aspirin intake in photoselective vaporization laser
treatment of benign prostate hyperplasia</title>
<author><name sortKey="Shao, I Hung" sort="Shao, I Hung" uniqKey="Shao I" first="I-Hung" last="Shao">I-Hung Shao</name>
<affiliation><nlm:aff id="af1-cia-8-265">Department of Urology, Chang Gung Memorial Hospital-Linko and Chang Gung University College of Medicine</nlm:aff>
<wicri:noCountry code="subfield">Chang Gung Memorial Hospital-Linko and Chang Gung University College of Medicine</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Hou, Chen Pang" sort="Hou, Chen Pang" uniqKey="Hou C" first="Chen-Pang" last="Hou">Chen-Pang Hou</name>
<affiliation><nlm:aff id="af1-cia-8-265">Department of Urology, Chang Gung Memorial Hospital-Linko and Chang Gung University College of Medicine</nlm:aff>
<wicri:noCountry code="subfield">Chang Gung Memorial Hospital-Linko and Chang Gung University College of Medicine</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Chen, Shao Ming" sort="Chen, Shao Ming" uniqKey="Chen S" first="Shao-Ming" last="Chen">Shao-Ming Chen</name>
<affiliation wicri:level="1"><nlm:aff id="af3-cia-8-265">Department of Urology, Taipei City Hospital, Heping Campus, Taipei, Taiwan, People’s Republic of China</nlm:aff>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Urology, Taipei City Hospital, Heping Campus, Taipei, Taiwan</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Chen, Chien Lun" sort="Chen, Chien Lun" uniqKey="Chen C" first="Chien-Lun" last="Chen">Chien-Lun Chen</name>
<affiliation><nlm:aff id="af1-cia-8-265">Department of Urology, Chang Gung Memorial Hospital-Linko and Chang Gung University College of Medicine</nlm:aff>
<wicri:noCountry code="subfield">Chang Gung Memorial Hospital-Linko and Chang Gung University College of Medicine</wicri:noCountry>
</affiliation>
<affiliation><nlm:aff id="af2-cia-8-265">Bioinformation Center, Chang Gung Memorial Hospital-Linko and Chang Gung University College of Medicine</nlm:aff>
<wicri:noCountry code="subfield">Chang Gung Memorial Hospital-Linko and Chang Gung University College of Medicine</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Lin, Yu Hsiang" sort="Lin, Yu Hsiang" uniqKey="Lin Y" first="Yu-Hsiang" last="Lin">Yu-Hsiang Lin</name>
<affiliation><nlm:aff id="af1-cia-8-265">Department of Urology, Chang Gung Memorial Hospital-Linko and Chang Gung University College of Medicine</nlm:aff>
<wicri:noCountry code="subfield">Chang Gung Memorial Hospital-Linko and Chang Gung University College of Medicine</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Chang, Phei Lang" sort="Chang, Phei Lang" uniqKey="Chang P" first="Phei-Lang" last="Chang">Phei-Lang Chang</name>
<affiliation><nlm:aff id="af1-cia-8-265">Department of Urology, Chang Gung Memorial Hospital-Linko and Chang Gung University College of Medicine</nlm:aff>
<wicri:noCountry code="subfield">Chang Gung Memorial Hospital-Linko and Chang Gung University College of Medicine</wicri:noCountry>
</affiliation>
<affiliation><nlm:aff id="af2-cia-8-265">Bioinformation Center, Chang Gung Memorial Hospital-Linko and Chang Gung University College of Medicine</nlm:aff>
<wicri:noCountry code="subfield">Chang Gung Memorial Hospital-Linko and Chang Gung University College of Medicine</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Tsui, Ke Hung" sort="Tsui, Ke Hung" uniqKey="Tsui K" first="Ke-Hung" last="Tsui">Ke-Hung Tsui</name>
<affiliation><nlm:aff id="af1-cia-8-265">Department of Urology, Chang Gung Memorial Hospital-Linko and Chang Gung University College of Medicine</nlm:aff>
<wicri:noCountry code="subfield">Chang Gung Memorial Hospital-Linko and Chang Gung University College of Medicine</wicri:noCountry>
</affiliation>
<affiliation><nlm:aff id="af2-cia-8-265">Bioinformation Center, Chang Gung Memorial Hospital-Linko and Chang Gung University College of Medicine</nlm:aff>
<wicri:noCountry code="subfield">Chang Gung Memorial Hospital-Linko and Chang Gung University College of Medicine</wicri:noCountry>
</affiliation>
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<series><title level="j">Clinical Interventions in Aging</title>
<idno type="ISSN">1176-9092</idno>
<idno type="eISSN">1178-1998</idno>
<imprint><date when="2013">2013</date>
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<front><div type="abstract" xml:lang="en"><p>Endoscopic surgical treatment has become an option to treat benign prostate hyperplasia. We
evaluated the safety and effectiveness of photoselective vaporization of the prostate (PVP) in
patients. We evaluated preoperative and perioperative parameters, functional outcomes, and adverse
events up to 12 months postoperatively of patients on oral anticoagulation therapy undergoing PVP,
and compared the results with patients who did not take anticoagulation therapy. A total of 89
patients who received photoselective vaporization laser for benign prostate hyperplasia from May
2006 to February 2011 in our hospital were enrolled in our study. The patients were divided into two
groups based on whether or not they were taking oral aspirin; 23 (25.8%) patients were
taking aspirin derivatives (aspirin group), and 66 (74.2%) were not taking aspirin
derivatives (control group). The mean prostate volume (58.8 mL vs 51 mL; <italic>P</italic>
= 0.16) and mean energy consumption (235,268 J vs 289,793 J; <italic>P</italic>
=
0.097) were comparable between the aspirin group and control group. The average postoperative
results of hemoglobin were 13.4 mg/ dL for the aspirin group versus 13.9 mg/dL for the control group
(<italic>P</italic>
= 0.327). A significantly higher maximum flow rates and 80%
improved post-void residual urine were noted during the followup. Postoperatively all variable
showed significant improvement starting at month 1 of followup and remained improved for the 12
month followup. Postoperative complications were low and comparable between groups. PVP was
characterized by excellent hemostatic properties and a very low intraoperative complication rate,
even in the patients who were taking aspirin. On the basis of our perioperative results, we
recommend PVP as a safe and effective procedure for patients with symptomatic benign prostate
hyperplasia when taking an aspirin derivative.</p>
</div>
</front>
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<pmc article-type="research-article"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Clin Interv Aging</journal-id>
<journal-id journal-id-type="iso-abbrev">Clin Interv Aging</journal-id>
<journal-title-group><journal-title>Clinical Interventions in Aging</journal-title>
</journal-title-group>
<issn pub-type="ppub">1176-9092</issn>
<issn pub-type="epub">1178-1998</issn>
<publisher><publisher-name>Dove Medical Press</publisher-name>
</publisher>
</journal-meta>
<article-meta><article-id pub-id-type="pmid">23662050</article-id>
<article-id pub-id-type="pmc">3646392</article-id>
<article-id pub-id-type="doi">10.2147/CIA.S41270</article-id>
<article-id pub-id-type="publisher-id">cia-8-265</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Original Research</subject>
</subj-group>
</article-categories>
<title-group><article-title>The safety and efficacy of aspirin intake in photoselective vaporization laser
treatment of benign prostate hyperplasia</article-title>
</title-group>
<contrib-group><contrib contrib-type="author"><name><surname>Shao</surname>
<given-names>I-Hung</given-names>
</name>
<xref ref-type="aff" rid="af1-cia-8-265"><sup>1</sup>
</xref>
<xref ref-type="author-notes" rid="fn1-cia-8-265"><sup>*</sup>
</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Hou</surname>
<given-names>Chen-Pang</given-names>
</name>
<xref ref-type="aff" rid="af1-cia-8-265"><sup>1</sup>
</xref>
<xref ref-type="author-notes" rid="fn1-cia-8-265"><sup>*</sup>
</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Chen</surname>
<given-names>Shao-Ming</given-names>
</name>
<xref ref-type="aff" rid="af3-cia-8-265"><sup>3</sup>
</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Chen</surname>
<given-names>Chien-Lun</given-names>
</name>
<xref ref-type="aff" rid="af1-cia-8-265"><sup>1</sup>
</xref>
<xref ref-type="aff" rid="af2-cia-8-265"><sup>2</sup>
</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Lin</surname>
<given-names>Yu-Hsiang</given-names>
</name>
<xref ref-type="aff" rid="af1-cia-8-265"><sup>1</sup>
</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Chang</surname>
<given-names>Phei-Lang</given-names>
</name>
<xref ref-type="aff" rid="af1-cia-8-265"><sup>1</sup>
</xref>
<xref ref-type="aff" rid="af2-cia-8-265"><sup>2</sup>
</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Tsui</surname>
<given-names>Ke-Hung</given-names>
</name>
<xref ref-type="corresp" rid="c1-cia-8-265"></xref>
<xref ref-type="aff" rid="af1-cia-8-265"><sup>1</sup>
</xref>
<xref ref-type="aff" rid="af2-cia-8-265"><sup>2</sup>
</xref>
</contrib>
</contrib-group>
<aff id="af1-cia-8-265"><label>1</label>
Department of Urology, Chang Gung Memorial Hospital-Linko and Chang Gung University College of Medicine</aff>
<aff id="af2-cia-8-265"><label>2</label>
Bioinformation Center, Chang Gung Memorial Hospital-Linko and Chang Gung University College of Medicine</aff>
<aff id="af3-cia-8-265"><label>3</label>
Department of Urology, Taipei City Hospital, Heping Campus, Taipei, Taiwan, People’s Republic of China</aff>
<author-notes><fn id="fn1-cia-8-265" fn-type="equal"><label>*</label>
<p>These authors contributed equally to this work</p>
</fn>
<corresp id="c1-cia-8-265">Correspondence: Ke-Hung Tsui, Chang Gung Memorial Hospital, Department of
Urology, Fu-shing Street, Gueishan, Taoyuan 333, Taiwan, People’s Republic of China, Tel
+886 2 2735 9577, Fax +886 2 735 8775, Email
<email>khtsui@yahoo.com</email>
</corresp>
</author-notes>
<pub-date pub-type="collection"><year>2013</year>
</pub-date>
<pmc-comment>Dove Press titles changed from ppub to collections in 2009.
Fake ppub written to satisfy Coll Date Type=ppub</pmc-comment>
<pub-date pub-type="ppub"><year>2013</year>
</pub-date>
<pub-date pub-type="epub"><day>09</day>
<month>3</month>
<year>2013</year>
</pub-date>
<volume>8</volume>
<fpage>265</fpage>
<lpage>269</lpage>
<history><date date-type="received"><day>08</day>
<month>3</month>
<year>2013</year>
</date>
</history>
<permissions><copyright-statement>© 2013 Shao et al, publisher and licensee Dove Medical Press
Ltd</copyright-statement>
<copyright-year>2013</copyright-year>
<license><license-p>This is an Open Access article which permits unrestricted noncommercial use, provided the
original work is properly cited.</license-p>
</license>
</permissions>
<abstract><p>Endoscopic surgical treatment has become an option to treat benign prostate hyperplasia. We
evaluated the safety and effectiveness of photoselective vaporization of the prostate (PVP) in
patients. We evaluated preoperative and perioperative parameters, functional outcomes, and adverse
events up to 12 months postoperatively of patients on oral anticoagulation therapy undergoing PVP,
and compared the results with patients who did not take anticoagulation therapy. A total of 89
patients who received photoselective vaporization laser for benign prostate hyperplasia from May
2006 to February 2011 in our hospital were enrolled in our study. The patients were divided into two
groups based on whether or not they were taking oral aspirin; 23 (25.8%) patients were
taking aspirin derivatives (aspirin group), and 66 (74.2%) were not taking aspirin
derivatives (control group). The mean prostate volume (58.8 mL vs 51 mL; <italic>P</italic>
= 0.16) and mean energy consumption (235,268 J vs 289,793 J; <italic>P</italic>
=
0.097) were comparable between the aspirin group and control group. The average postoperative
results of hemoglobin were 13.4 mg/ dL for the aspirin group versus 13.9 mg/dL for the control group
(<italic>P</italic>
= 0.327). A significantly higher maximum flow rates and 80%
improved post-void residual urine were noted during the followup. Postoperatively all variable
showed significant improvement starting at month 1 of followup and remained improved for the 12
month followup. Postoperative complications were low and comparable between groups. PVP was
characterized by excellent hemostatic properties and a very low intraoperative complication rate,
even in the patients who were taking aspirin. On the basis of our perioperative results, we
recommend PVP as a safe and effective procedure for patients with symptomatic benign prostate
hyperplasia when taking an aspirin derivative.</p>
</abstract>
<kwd-group><kwd>prostate gland</kwd>
<kwd>benign prostatic hyperplasia</kwd>
<kwd>laser</kwd>
<kwd>elderly</kwd>
<kwd>green light laser</kwd>
</kwd-group>
</article-meta>
</front>
<floats-group><table-wrap id="t1-cia-8-265" position="float"><label>Table 1</label>
<caption><p>Characteristics of the patients and comparison between non-aspirin group and aspirin group</p>
</caption>
<table frame="hsides" rules="groups"><thead><tr><th align="left" valign="top" rowspan="1" colspan="1"></th>
<th align="left" valign="top" rowspan="1" colspan="1"><bold>Non–aspirin group (mean/range)</bold>
</th>
<th align="left" valign="top" rowspan="1" colspan="1"><bold>Aspirin group (mean/range)</bold>
</th>
<th align="left" valign="top" rowspan="1" colspan="1"><bold><italic>P</italic>
-value</bold>
</th>
</tr>
</thead>
<tbody><tr><td align="left" valign="top" rowspan="1" colspan="1">Age (year-old)</td>
<td align="left" valign="top" rowspan="1" colspan="1"></td>
<td align="left" valign="top" rowspan="1" colspan="1"></td>
<td align="left" valign="top" rowspan="1" colspan="1"></td>
</tr>
<tr><td align="left" valign="top" rowspan="1" colspan="1"> Mean age (range): 72.0 (52–93)</td>
<td align="left" valign="top" rowspan="1" colspan="1">71.7 (52–93)</td>
<td align="left" valign="top" rowspan="1" colspan="1">73.0 (56–86)</td>
<td align="left" valign="top" rowspan="1" colspan="1">0.561</td>
</tr>
<tr><td align="left" valign="top" rowspan="1" colspan="1">Total prostate volume</td>
<td align="left" valign="top" rowspan="1" colspan="1"></td>
<td align="left" valign="top" rowspan="1" colspan="1"></td>
<td align="left" valign="top" rowspan="1" colspan="1"></td>
</tr>
<tr><td align="left" valign="top" rowspan="1" colspan="1"> 53.0 (25.3–122.1) (cm<sup>3</sup>
)</td>
<td align="left" valign="top" rowspan="1" colspan="1">51.0 (28.7–90.0)</td>
<td align="left" valign="top" rowspan="1" colspan="1">58.8 (25.3–122.07)</td>
<td align="left" valign="top" rowspan="1" colspan="1">0.160</td>
</tr>
<tr><td align="left" valign="top" rowspan="1" colspan="1">Serum PSA level</td>
<td align="left" valign="top" rowspan="1" colspan="1"></td>
<td align="left" valign="top" rowspan="1" colspan="1"></td>
<td align="left" valign="top" rowspan="1" colspan="1"></td>
</tr>
<tr><td align="left" valign="top" rowspan="1" colspan="1"> 7.15 (0.30–38.6) (ng/mL)</td>
<td align="left" valign="top" rowspan="1" colspan="1">7.62 (0.42–38.6)</td>
<td align="left" valign="top" rowspan="1" colspan="1">5.79 (0.302–13.32)</td>
<td align="left" valign="top" rowspan="1" colspan="1">0.242</td>
</tr>
<tr><td align="left" valign="top" rowspan="1" colspan="1">Hemoglobin</td>
<td align="left" valign="top" rowspan="1" colspan="1"></td>
<td align="left" valign="top" rowspan="1" colspan="1"></td>
<td align="left" valign="top" rowspan="1" colspan="1"></td>
</tr>
<tr><td align="left" valign="top" rowspan="1" colspan="1"> 13.7 (8.8–17.3) (mg/dL)</td>
<td align="left" valign="top" rowspan="1" colspan="1">13.9 (9.3–17.3)</td>
<td align="left" valign="top" rowspan="1" colspan="1">13.4 (8.8–16.8)</td>
<td align="left" valign="top" rowspan="1" colspan="1">0.327</td>
</tr>
<tr><td align="left" valign="top" rowspan="1" colspan="1">PT seconds</td>
<td align="left" valign="top" rowspan="1" colspan="1"></td>
<td align="left" valign="top" rowspan="1" colspan="1"></td>
<td align="left" valign="top" rowspan="1" colspan="1"></td>
</tr>
<tr><td align="left" valign="top" rowspan="1" colspan="1"> 11.3 (9.9–17.7)</td>
<td align="left" valign="top" rowspan="1" colspan="1">11.2 (9.9–17.7)</td>
<td align="left" valign="top" rowspan="1" colspan="1">11.6 (10.0–13.0)</td>
<td align="left" valign="top" rowspan="1" colspan="1">0.115</td>
</tr>
<tr><td align="left" valign="top" rowspan="1" colspan="1">APTT seconds</td>
<td align="left" valign="top" rowspan="1" colspan="1"></td>
<td align="left" valign="top" rowspan="1" colspan="1"></td>
<td align="left" valign="top" rowspan="1" colspan="1"></td>
</tr>
<tr><td align="left" valign="top" rowspan="1" colspan="1"> 27.3 (20.9–37.2)</td>
<td align="left" valign="top" rowspan="1" colspan="1">27.3 (20.9–37.2)</td>
<td align="left" valign="top" rowspan="1" colspan="1">27.3 (22.9–33.0)</td>
<td align="left" valign="top" rowspan="1" colspan="1">0.979</td>
</tr>
<tr><td align="left" valign="top" rowspan="1" colspan="1">Platelet count</td>
<td align="left" valign="top" rowspan="1" colspan="1"></td>
<td align="left" valign="top" rowspan="1" colspan="1"></td>
<td align="left" valign="top" rowspan="1" colspan="1"></td>
</tr>
<tr><td align="left" valign="top" rowspan="1" colspan="1"> 205056 (114,000–400,000)</td>
<td align="left" valign="top" rowspan="1" colspan="1">202,742 (114,000–400,000)</td>
<td align="left" valign="top" rowspan="1" colspan="1">211,695 (134,000–332,000)</td>
<td align="left" valign="top" rowspan="1" colspan="1">0.493</td>
</tr>
<tr><td align="left" valign="top" rowspan="1" colspan="1">IPSS score</td>
<td align="left" valign="top" rowspan="1" colspan="1"></td>
<td align="left" valign="top" rowspan="1" colspan="1"></td>
<td align="left" valign="top" rowspan="1" colspan="1"></td>
</tr>
<tr><td align="left" valign="top" rowspan="1" colspan="1"> 24.9 (15–35)</td>
<td align="left" valign="top" rowspan="1" colspan="1">24.9 (15–35)</td>
<td align="left" valign="top" rowspan="1" colspan="1">25.0 (19–33)</td>
<td align="left" valign="top" rowspan="1" colspan="1">0.883</td>
</tr>
<tr><td align="left" valign="top" rowspan="1" colspan="1">Lasing time</td>
<td align="left" valign="top" rowspan="1" colspan="1"></td>
<td align="left" valign="top" rowspan="1" colspan="1"></td>
<td align="left" valign="top" rowspan="1" colspan="1"></td>
</tr>
<tr><td align="left" valign="top" rowspan="1" colspan="1"> 54.7 (10.0–135) (minutes)</td>
<td align="left" valign="top" rowspan="1" colspan="1"></td>
<td align="left" valign="top" rowspan="1" colspan="1"></td>
<td align="left" valign="top" rowspan="1" colspan="1"></td>
</tr>
<tr><td align="left" valign="top" rowspan="1" colspan="1">Energy consumption</td>
<td align="left" valign="top" rowspan="1" colspan="1"></td>
<td align="left" valign="top" rowspan="1" colspan="1"></td>
<td align="left" valign="top" rowspan="1" colspan="1"></td>
</tr>
<tr><td align="left" valign="top" rowspan="1" colspan="1"> 275,702 (37,278–597,227) (Joule)</td>
<td align="left" valign="top" rowspan="1" colspan="1">289,793 (37,278–597,227)</td>
<td align="left" valign="top" rowspan="1" colspan="1">235,268 (71,864–557,902)</td>
<td align="left" valign="top" rowspan="1" colspan="1">0.097</td>
</tr>
<tr><td colspan="2" align="left" valign="top" rowspan="1">Energy consumption per prostate volume
(Joule/cm<sup>3</sup>
)</td>
<td align="left" valign="top" rowspan="1" colspan="1"></td>
<td align="left" valign="top" rowspan="1" colspan="1"></td>
</tr>
<tr><td align="left" valign="top" rowspan="1" colspan="1"> 5412 (1165–15,121)</td>
<td align="left" valign="top" rowspan="1" colspan="1">5801 (1165–15,121)</td>
<td align="left" valign="top" rowspan="1" colspan="1">4297 (1311–10,811)</td>
<td align="left" valign="top" rowspan="1" colspan="1">0.017</td>
</tr>
<tr><td align="left" valign="top" rowspan="1" colspan="1">Aspirin prescription</td>
<td align="left" valign="top" rowspan="1" colspan="1"></td>
<td align="left" valign="top" rowspan="1" colspan="1"></td>
<td align="left" valign="top" rowspan="1" colspan="1"></td>
</tr>
<tr><td align="left" valign="top" rowspan="1" colspan="1"> Yes 23</td>
<td align="left" valign="top" rowspan="1" colspan="1"></td>
<td align="left" valign="top" rowspan="1" colspan="1"></td>
<td align="left" valign="top" rowspan="1" colspan="1"></td>
</tr>
<tr><td align="left" valign="top" rowspan="1" colspan="1"> No 66</td>
<td align="left" valign="top" rowspan="1" colspan="1"></td>
<td align="left" valign="top" rowspan="1" colspan="1"></td>
<td align="left" valign="top" rowspan="1" colspan="1"></td>
</tr>
</tbody>
</table>
<table-wrap-foot><fn id="tfn1-cia-8-265"><p><bold>Abbreviations:</bold>
PSA, prostate-specific antigen; PT, prothrombin time; APTT, activated
partial thromboplastin time; IPSS, International Prostate Symptom Score.</p>
</fn>
</table-wrap-foot>
</table-wrap>
<table-wrap id="t2-cia-8-265" position="float"><label>Table 2</label>
<caption><p>Results of uroflow data</p>
</caption>
<table frame="hsides" rules="groups"><thead><tr><th align="left" valign="top" rowspan="1" colspan="1"><bold>(mL/second)</bold>
</th>
<th align="left" valign="top" rowspan="1" colspan="1"><bold>Non-aspirin group (mean)</bold>
</th>
<th align="left" valign="top" rowspan="1" colspan="1"><bold>Aspirin group (mean/range)</bold>
</th>
<th align="left" valign="top" rowspan="1" colspan="1"><bold><italic>P</italic>
-value</bold>
</th>
</tr>
</thead>
<tbody><tr><td align="left" valign="top" rowspan="1" colspan="1">Preoperative peak flow rate</td>
<td align="left" valign="top" rowspan="1" colspan="1">8.71</td>
<td align="left" valign="top" rowspan="1" colspan="1">7.88</td>
<td align="left" valign="top" rowspan="1" colspan="1">0.681</td>
</tr>
<tr><td align="left" valign="top" rowspan="1" colspan="1">Postoperative peak flow rate</td>
<td align="left" valign="top" rowspan="1" colspan="1">13.64</td>
<td align="left" valign="top" rowspan="1" colspan="1">13.54</td>
<td align="left" valign="top" rowspan="1" colspan="1">0.967</td>
</tr>
<tr><td align="left" valign="top" rowspan="1" colspan="1">Preoperative average flow rate</td>
<td align="left" valign="top" rowspan="1" colspan="1">3.76</td>
<td align="left" valign="top" rowspan="1" colspan="1">3.62</td>
<td align="left" valign="top" rowspan="1" colspan="1">0.869</td>
</tr>
<tr><td align="left" valign="top" rowspan="1" colspan="1">Postoperative average flow rate</td>
<td align="left" valign="top" rowspan="1" colspan="1">6.42</td>
<td align="left" valign="top" rowspan="1" colspan="1">6.57</td>
<td align="left" valign="top" rowspan="1" colspan="1">0.896</td>
</tr>
</tbody>
</table>
</table-wrap>
</floats-group>
</pmc>
</record>
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