Transcatheter aortic valve replacement: transapical resection of the aortic valve in vivo
Identifieur interne : 000274 ( Pmc/Curation ); précédent : 000273; suivant : 000275Transcatheter aortic valve replacement: transapical resection of the aortic valve in vivo
Auteurs : René Bombien Quaden [Allemagne] ; Monika Leester-Schaedel [Allemagne] ; Lucian Lozonschi [États-Unis] ; Georg Lutter [Allemagne]Source :
- Interactive Cardiovascular and Thoracic Surgery [ 1569-9293 ] ; 2012.
Abstract
The resection of pulmonary valves has already been demonstrated in an experimental beating-heart model. The aim of this study was to analyse the transapical laser-assisted resection of aortic valves in an
Url:
DOI: 10.1093/icvts/ivs246
PubMed: 22707518
PubMed Central: 3422953
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xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Leester Schaedel, Monika" sort="Leester Schaedel, Monika" uniqKey="Leester Schaedel M" first="Monika" last="Leester-Schaedel">Monika Leester-Schaedel</name><affiliation wicri:level="1"><nlm:aff id="af3"><institution>Institute for Microtechnology</institution>,<institution>University of Braunschweig</institution>,<addr-line>Braunschweig</addr-line>,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Lozonschi, Lucian" sort="Lozonschi, Lucian" uniqKey="Lozonschi L" first="Lucian" last="Lozonschi">Lucian Lozonschi</name><affiliation wicri:level="1"><nlm:aff id="af4"><addr-line>Divison of Cardiothoracic Surgery</addr-line>,<institution>University of Wisconsin School of Medicine</institution>,<addr-line>Madison, WI</addr-line>,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Lutter, Georg" sort="Lutter, Georg" uniqKey="Lutter G" first="Georg" last="Lutter">Georg Lutter</name><affiliation wicri:level="1"><nlm:aff id="af2"><addr-line>Department of Cardiovascular Surgery</addr-line>,<institution>University Hospital Schleswig-Holstein</institution>,<addr-line>Campus Kiel, Kiel</addr-line>,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">22707518</idno><idno type="pmc">3422953</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3422953</idno><idno type="RBID">PMC:3422953</idno><idno type="doi">10.1093/icvts/ivs246</idno><date when="2012">2012</date><idno type="wicri:Area/Pmc/Corpus">000274</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000274</idno><idno type="wicri:Area/Pmc/Curation">000274</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000274</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Transcatheter aortic valve replacement: transapical resection of the aortic valve <italic>in vivo</italic></title><author><name sortKey="Bombien Quaden, Rene" sort="Bombien Quaden, Rene" uniqKey="Bombien Quaden R" first="René" last="Bombien Quaden">René Bombien Quaden</name><affiliation wicri:level="1"><nlm:aff id="af1"><addr-line>Department of Surgery—Vascular and Endovascular Surgery</addr-line>,<institution>University of Munich—Grosshadern</institution>,<addr-line>Munich</addr-line>,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="af2"><addr-line>Department of Cardiovascular Surgery</addr-line>,<institution>University Hospital Schleswig-Holstein</institution>,<addr-line>Campus Kiel, Kiel</addr-line>,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Leester Schaedel, Monika" sort="Leester Schaedel, Monika" uniqKey="Leester Schaedel M" first="Monika" last="Leester-Schaedel">Monika Leester-Schaedel</name><affiliation wicri:level="1"><nlm:aff id="af3"><institution>Institute for Microtechnology</institution>,<institution>University of Braunschweig</institution>,<addr-line>Braunschweig</addr-line>,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Lozonschi, Lucian" sort="Lozonschi, Lucian" uniqKey="Lozonschi L" first="Lucian" last="Lozonschi">Lucian Lozonschi</name><affiliation wicri:level="1"><nlm:aff id="af4"><addr-line>Divison of Cardiothoracic Surgery</addr-line>,<institution>University of Wisconsin School of Medicine</institution>,<addr-line>Madison, WI</addr-line>,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Lutter, Georg" sort="Lutter, Georg" uniqKey="Lutter G" first="Georg" last="Lutter">Georg Lutter</name><affiliation wicri:level="1"><nlm:aff id="af2"><addr-line>Department of Cardiovascular Surgery</addr-line>,<institution>University Hospital Schleswig-Holstein</institution>,<addr-line>Campus Kiel, Kiel</addr-line>,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author></analytic><series><title level="j">Interactive Cardiovascular and Thoracic Surgery</title><idno type="ISSN">1569-9293</idno><idno type="eISSN">1569-9285</idno><imprint><date when="2012">2012</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>The resection of pulmonary valves has already been demonstrated in an experimental beating-heart model. The aim of this study was to analyse the transapical laser-assisted resection of aortic valves in an <italic>in vivo</italic> porcine model in a non-beating heart. The resection was performed in a porcine model (<italic>n</italic> = 10) using a Thullium:YAG laser. After establishing a standard extracorporeal circulatory support, the aortic valve isolation chamber (AVIC) system was inserted transapically. The resection of the aortic leaflets was carried out step-by-step in the arrested heart. The AVIC implantation, the resection process, and the gross anatomy of intracardiac lesions were analysed. The procedure for installing the AVIC took 5.8 ± 1.5 min. A sealed chamber was achieved in 9/10 cases. The resection of the valves was performed in 8/10 and completed in 7/10 cases. The resection took, on average, 7.4 ± 2.7 min/cusp. In 9/10 cases, the sealing was sufficient. Gross anatomy and histological analysis demonstrated only superficial damage to the surrounding tissue. In this study, the <italic>in vivo</italic> on-pump isolation of the left ventricular outflow tract and the laser resection of the native aortic valve could be demonstrated successfully. Nevertheless, this model is the next step towards a beating-heart resection of the aortic valve using the isolation chamber.</p></div></front></TEI><pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Interact Cardiovasc Thorac Surg</journal-id><journal-id journal-id-type="iso-abbrev">Interact Cardiovasc Thorac Surg</journal-id><journal-id journal-id-type="publisher-id">icvtsurg</journal-id><journal-id journal-id-type="hwp">icvtsurg</journal-id><journal-title-group><journal-title>Interactive Cardiovascular and Thoracic Surgery</journal-title></journal-title-group><issn pub-type="ppub">1569-9293</issn><issn pub-type="epub">1569-9285</issn><publisher><publisher-name>Oxford University Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">22707518</article-id><article-id pub-id-type="pmc">3422953</article-id><article-id pub-id-type="doi">10.1093/icvts/ivs246</article-id><article-id pub-id-type="publisher-id">ivs246</article-id><article-categories><subj-group subj-group-type="heading"><subject>New Ideas</subject><subj-group subj-group-type="heading"><subject>Adult Cardiac</subject></subj-group></subj-group></article-categories><title-group><article-title>Transcatheter aortic valve replacement: transapical resection of the aortic valve <italic>in vivo</italic></article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Bombien Quaden</surname><given-names>René</given-names></name><xref ref-type="aff" rid="af1">1</xref><xref ref-type="aff" rid="af2">2</xref><xref ref-type="corresp" rid="cor1">*</xref></contrib><contrib contrib-type="author"><name><surname>Leester-Schaedel</surname><given-names>Monika</given-names></name><xref ref-type="aff" rid="af3">3</xref></contrib><contrib contrib-type="author"><name><surname>Lozonschi</surname><given-names>Lucian</given-names></name><xref ref-type="aff" rid="af4">4</xref></contrib><contrib contrib-type="author"><name><surname>Lutter</surname><given-names>Georg</given-names></name><xref ref-type="aff" rid="af2">2</xref></contrib></contrib-group><aff id="af1"><label>1</label><addr-line>Department of Surgery—Vascular and Endovascular Surgery</addr-line>,<institution>University of Munich—Grosshadern</institution>,<addr-line>Munich</addr-line>,<country>Germany</country></aff><aff id="af2"><label>2</label><addr-line>Department of Cardiovascular Surgery</addr-line>,<institution>University Hospital Schleswig-Holstein</institution>,<addr-line>Campus Kiel, Kiel</addr-line>,<country>Germany</country></aff><aff id="af3"><label>3</label><institution>Institute for Microtechnology</institution>,<institution>University of Braunschweig</institution>,<addr-line>Braunschweig</addr-line>,<country>Germany</country></aff><aff id="af4"><label>4</label><addr-line>Divison of Cardiothoracic Surgery</addr-line>,<institution>University of Wisconsin School of Medicine</institution>,<addr-line>Madison, WI</addr-line>,<country>USA</country></aff><author-notes><corresp id="cor1"><label>*</label>Corresponding author: Department of Surgery—Vascular and Endovascular Surgery, University of Munich—Grosshadern, Munich, Germany. Tel: +<phone>49-89-70955059</phone>; fax: +<fax>49-89-70958873</fax>; e-mail: <email>rbombien@quabo.de</email> (R. Bombien Quaden).</corresp></author-notes><pub-date pub-type="ppub"><month>9</month><year>2012</year></pub-date><pub-date pub-type="epub"><day>15</day><month>6</month><year>2012</year></pub-date><volume>15</volume><issue>3</issue><fpage>348</fpage><lpage>351</lpage><history><date date-type="received"><day>13</day><month>11</month><year>2011</year></date><date date-type="rev-recd"><day>29</day><month>2</month><year>2012</year></date><date date-type="accepted"><day>12</day><month>3</month><year>2012</year></date></history><permissions><copyright-statement>© The Author 2012. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery. All rights reserved.</copyright-statement><copyright-year>2012</copyright-year></permissions><self-uri content-type="pdf" xlink:type="simple" xlink:href="ivs246.pdf"></self-uri><abstract><p>The resection of pulmonary valves has already been demonstrated in an experimental beating-heart model. The aim of this study was to analyse the transapical laser-assisted resection of aortic valves in an <italic>in vivo</italic> porcine model in a non-beating heart. The resection was performed in a porcine model (<italic>n</italic> = 10) using a Thullium:YAG laser. After establishing a standard extracorporeal circulatory support, the aortic valve isolation chamber (AVIC) system was inserted transapically. The resection of the aortic leaflets was carried out step-by-step in the arrested heart. The AVIC implantation, the resection process, and the gross anatomy of intracardiac lesions were analysed. The procedure for installing the AVIC took 5.8 ± 1.5 min. A sealed chamber was achieved in 9/10 cases. The resection of the valves was performed in 8/10 and completed in 7/10 cases. The resection took, on average, 7.4 ± 2.7 min/cusp. In 9/10 cases, the sealing was sufficient. Gross anatomy and histological analysis demonstrated only superficial damage to the surrounding tissue. In this study, the <italic>in vivo</italic> on-pump isolation of the left ventricular outflow tract and the laser resection of the native aortic valve could be demonstrated successfully. Nevertheless, this model is the next step towards a beating-heart resection of the aortic valve using the isolation chamber.</p></abstract><kwd-group><kwd>Resection</kwd><kwd>Transapical</kwd><kwd>Aortic valve</kwd><kwd>Endovascular</kwd><kwd><italic>In vivo</italic></kwd></kwd-group><counts><page-count count="4"></page-count></counts></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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